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Marco Fernandes. Completed the Doutoramento in Genetics, Genomics and Systems Medicine in 2018 by University of Glasgow. Is Researcher in University of St Andrews. Published 24 articles in journals. Has 4 section(s) of books. Works in the area(s) of Exact Sciences with emphasis on Computer and Information Sciences with emphasis on Bioinformatics. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Oxidative stress ; Alzheimer's Disease; Family History of Alzheimer's Disease; Blood Pressure; mendelian randomization; genetic variants; .
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Identification

Personal identification

Full name
Marco Fernandes

Citation names

  • Fernandes, Marco

Author identifiers

Ciência ID
3D14-AF55-C3A3
ORCID iD
0000-0002-4768-0934

Telephones

Telephone
  • (+44) (0)1334 Ext.: 46 (Professional)

Addresses

  • School of Medicine, N Haugh, KY16 9TF, St Andrews, Angus, United Kingdom (Professional)

Websites

  • https://research-portal.st-andrews.ac.uk/en/persons/marco-ferreira-fernandes (Scholar)

Knowledge fields

  • Exact Sciences - Computer and Information Sciences - Bioinformatics

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Portuguese (Mother tongue)
Education
Degree Classification
2018
Concluded
 Genetics, Genomics and Systems Medicine (Doutoramento)
University of Glasgow, United Kingdom
Affiliation

Science

Category
Host institution 		Employer
2023/08/01 - Current Researcher (Research) University of St Andrews, United Kingdom
University of St Andrews Bute Medical School, United Kingdom
2019/03/11 - 2023/07/31 Researcher (Research) Dep. Psychiatry - ARUK Oxford Drug Discovery Institute, University of Oxford, United Kingdom
Projects

Grant

Designation Funders
2014/09 - 2017/08 Clinical and system –omics for the identification of the MOlecular DEterminants of established Chronic Kidney Disease
grant.608332
 European Commission
2011/04 - 2013/03 ASSAY - Assessment of fate and effects of Silver nanoparticleS in Aquatic ecosYstems
grant.Provided by PTCRIS: 113649
 Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
Outputs

Publications

Book chapter
  1. Fernandes, Marco. "Integrative Systems Biology Resources and Approaches in Disease Analytics". 2019.
    10.5772/intechopen.84834
  2. Fernandes, Marco. "Cheminformatics and Computational Approaches in Metabolomics". 2019.
    10.15586/computationalbiology.2019
  3. "Cardiovascular Disease and Oxidative Stress". In Fundamentals, Enzyme Inhibitors, and Enzymes in Health and Diseases, edited by Peter Grunwald. Jenny Stanford Publishing, 2019.
    10.1201/9780429295034
  4. Fernandes, Marco. "Molecular Model for CKD". 2018.
Conference abstract
  1. "Teaching old drugs new tricks: Do cardiovascular medications effect cognitive decline?". 2020.
    10.1002/alz.040554
Journal article
  1. Najaf Amin; Jun Liu; Bruno Bonnechere; Siamak MahmoudianDehkordi; Matthias Arnold; Richa Batra; Yu-Jie Chiou; et al. "Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals". JAMA Psychiatry 80 6 (2023): 597-597. http://dx.doi.org/10.1001/jamapsychiatry.2023.0685.
    10.1001/jamapsychiatry.2023.0685
  2. Cornelia M van Duijn; Najaf Amin; Jun Liu; Bruno Bonnechere; Siamak MahmoudianDehkordi; Matthias Arnold; Richa Batra; et al. "Interplay of the human exposome, metabolome and gut microbiome in dementia and major depression". Alzheimer's & Dementia 18 S4 (2022): http://dx.doi.org/10.1002/alz.067261.
    10.1002/alz.067261
  3. Marco Fernandes; Evangeline M. Foster; Adria Dangla-Valls; Philip Hublitz; Menelaos Pangalos; Simon Lovestone; Elena M. Ribe; Noel J. Buckley. "Glycosylated clusterin species facilitate Aß toxicity in human neurons". Scientific Reports 12 1 (2022): http://dx.doi.org/10.1038/s41598-022-23167-z.
    10.1038/s41598-022-23167-z
  4. Danielle Newby; Andrew Brent Linden; Marco Fernandes; Yasmina Molero; Laura Winchester; William Sproviero; Upamanyu Ghose; et al. "Comparative effect of metformin versus sulfonylureas with dementia and Parkinson’s disease risk in US patients over 50 with type 2 diabetes mellitus". BMJ Open Diabetes Research & Care 10 5 (2022): e003036-e003036. http://dx.doi.org/10.1136/bmjdrc-2022-003036.
    10.1136/bmjdrc-2022-003036
  5. Angelique Stalmach; Ines Boehm; Marco Fernandes; Alison Rutter; Richard J. E. Skipworth; Holger Husi. "Gene Ontology (GO)-Driven Inference of Candidate Proteomic Markers Associated with Muscle Atrophy Conditions". Molecules (2022): https://doi.org/10.3390/molecules27175514.
    10.3390/molecules27175514
  6. Danielle Newby; Laura Winchester; William Sproviero; Marco Fernandes; Upamanyu Ghose; Donald Lyall; Lenore J. Launer; Alejo J. Nevado-Holgado. "The relationship between isolated hypertension with brain volumes in UK Biobank". Brain and Behavior 12 5 (2022): http://dx.doi.org/10.1002/brb3.2525.
    10.1002/brb3.2525
  7. Zhenpeng Li; Andrey Kormilitzin; Marco Fernandes; Nemanja Vaci; Qiang Liu; Danielle Newby; Sarah Goodday; et al. "Validation of UK Biobank data for mental health outcomes: A pilot study using secondary care electronic health records". International Journal of Medical Informatics 160 (2022): 104704-104704. https://doi.org/10.1016/j.ijmedinf.2022.104704.
    10.1016/j.ijmedinf.2022.104704
  8. Fernandes M; Husi H. "ORA , FCS , and PT Strategies in Functional Enrichment Analysis.". Methods in molecular biology (Clifton, N.J.) (2021): http://europepmc.org/abstract/med/34236661.
    10.1007/978-1-0716-1641-3_10
  9. Fernandes, Marco. "High Blood Pressure and Risk of Dementia: a Two-Sample Mendelian Randomization study in the UK Biobank". Biological Psychiatry (2020): https://www.sciencedirect.com/science/article/pii/S0006322320321466.
    https://doi.org/10.1016/j.biopsych.2020.12.015
  10. Fernandes, Marco. "Identification of diagnostic upper gastrointestinal cancer tissue type-specific urinary biomarkers". (2019): http://dx.doi.org/10.3892/br.2019.1190.
    10.3892/br.2019.1190
  11. "The Many Facets of Fabry Disease in the Kidney- Heart Axis". Journal of Nephrology & Kidney Diseases. 2018;1(2):120 (2018):
  12. Marco Fernandes; Alisha Patel; Holger Husi; Aldrin V. Gomes. "C/VDdb: A multi-omics expression profiling database for a knowledge-driven approach in cardiovascular disease (CVD)". PLOS ONE 13 11 (2018): e0207371-e0207371. https://doi.org/10.1371%2Fjournal.pone.0207371.
    10.1371/journal.pone.0207371
  13. Marco Fernandes; Holger Husi. "Establishment of a integrative multi-omics expression database CKDdb in the context of chronic kidney disease (CKD)". Scientific Reports 7 (2017): 40367-40367. https://doi.org/10.1038%2Fsrep40367.
    10.1038/srep40367
  14. Fernandes, Marco. "Phytotoxicity of silver nanoparticles to Lemna minor: Surface coating and exposure period-related effects". Science of The Total Environment (2017): https://www.sciencedirect.com/science/article/pii/S004896971732627X.
    https://doi.org/10.1016/j.scitotenv.2017.09.275
  15. Marco Fernandes; Holger Husi. "Integrative Systems Biology Investigation of Fabry Disease". Diseases 4 4 (2016): 35-35. https://doi.org/10.3390%2Fdiseases4040035.
    10.3390/diseases4040035
  16. Magdalena Krochmal; Marco Fernandes; Szymon Filip; Claudia Pontillo; Joachim Jankowski; Holger Husi; Jerome Zoidakis; Harald Mischak; Antonia Vlahou. "SP281PEPTICKDDB - PEPTIDE-CENTRIC DATABASE FOR THE INVESTIGATION OF CHRONIC KIDNEY DISEASE DEVELOPMENT AND PROGRESSION". Nephrology Dialysis Transplantation 31 suppl{\_ (2016): i181-i181. https://doi.org/10.1093%2Fndt%2Fgfw164.25.
    10.1093/ndt/gfw164.25
  17. Marco Fernandes; Christian Delles; Holger Husi. "SP236MULTI-OMICS DATA INTEGRATION IN THE CONTEXT OF PRIMARY GLOMERULONEPHRITIS". Nephrology Dialysis Transplantation 31 suppl{\_ (2016): i165-i165. https://doi.org/10.1093%2Fndt%2Fgfw163.17.
    10.1093/ndt/gfw163.17
  18. Theofilos Papadopoulos; Magdalena Krochmal; Katryna Cisek; Marco Fernandes; Holger Husi; Robert Stevens; Jean-Loup Bascands; Joost P. Schanstra; Julie Klein. "Omics databases on kidney disease: where they can be found and how to benefit from them". Clinical Kidney Journal 9 3 (2016): 343-352. https://doi.org/10.1093%2Fckj%2Fsfv155.
    10.1093/ckj/sfv155
  19. Magdalena Krochmal; Marco Fernandes; Szymon Filip; Claudia Pontillo; Holger Husi; Jerome Zoidakis; Harald Mischak; Antonia Vlahou; Joachim Jankowski. "PeptiCKDdb—peptide- and protein-centric database for the investigation of genesis and progression of chronic kidney disease". Database 2016 (2016): baw128-baw128. https://doi.org/10.1093%2Fdatabase%2Fbaw128.
    10.1093/database/baw128
  20. Krochmal, Magdalena; Cisek, Katryna; Fernandes, Marco; Husi, Holger; Jankowski, Joachim; Zoidakis, Jerome; Vlahou, Antonia; Mischak, Harald. "MP266DEVELOPMENT OF IGA NEPHROPATHY MOLECULAR MODEL BASED ON AN INTEGRATIVE ANALYSIS OF -OMICS DATA". Nephrology Dialysis Transplantation 31 suppl_1 (2016): i428-i429. http://dx.doi.org/10.1093/ndt/gfw188.22.
    10.1093/ndt/gfw188.22
  21. Marco Fernandes; Holger Husi. "FP222THE CHRONIC KIDNEY DISEASE DATABASE (CKDdb)". Nephrology Dialysis Transplantation 30 suppl{\_ (2015): iii141-iii141. https://doi.org/10.1093%2Fndt%2Fgfv173.04.
    10.1093/ndt/gfv173.04
  22. Scott W. Robinson; Marco Fernandes; Holger Husi. "Current advances in systems and integrative biology". Computational and Structural Biotechnology Journal 11 18 (2014): 35-46. https://doi.org/10.1016%2Fj.csbj.2014.08.007.
    10.1016/j.csbj.2014.08.007
  23. Marco Fernandes; Rhaul Oliveira; Maria Jesus; Sara Aguiar; Susana Pereira; Rui Vitorino; António AJ Nogueira; Francisco Amado. "Ecotoxicoproteomics as an early tool for molecular events: exposure to silver nanoparticles". Current Opinion in Biotechnology 24 (2013): S66-S66. https://doi.org/10.1016%2Fj.copbio.2013.05.178.
    10.1016/j.copbio.2013.05.178
  24. Andreia C. M. Rodrigues; Fátima T. Jesus; Marco A. F. Fernandes; Fernando Morgado; Amadeu M. V. M. Soares; Sizenando N. Abreu. "Mercury Toxicity to Freshwater Organisms: Extrapolation Using Species Sensitivity Distribution". Bulletin of Environmental Contamination and Toxicology 91 2 (2013): 191-196. https://doi.org/10.1007%2Fs00128-013-1029-0.
    10.1007/s00128-013-1029-0
Preprint
  1. William Sproviero; Upamanyu Ghose; Laura Winchester; Marco Fernandes; Danielle Newby; Daisy Sproviero; Najaf Amin; et al. "The impact of Short Tandem Repeats on grey matter brain imaging derived phenotypes in UK Biobank". 2023. http://dx.doi.org/10.1101/2023.02.27.23286496.
    10.1101/2023.02.27.23286496
  2. Upamanyu Ghose; William Sproviero; Laura Winchester; Marco Fernandes; Danielle Newby; Brittany S. Ulm; Liu Shi; et al. "Genome wide association neural networks (GWANN) identify novel genes linked to family history of Alzheimer’s disease in the UK Biobank". 2022. http://dx.doi.org/10.1101/2022.06.10.22276251.
    10.1101/2022.06.10.22276251
  3. "Longitudinal analysis of UK Biobank participants suggests age and APOE-dependent alterations of energy metabolism in development of dementia". 2022. http://dx.doi.org/10.1101/2022.02.25.22271530.
    10.1101/2022.02.25.22271530

Other

Other output
  1. C/VDdb: a multi-omics expression profiling database for a knowledge-driven approach in cardiovascular disease (CVD). 2018. Marco Fernandes; Alisha Patel; Holger Husi. https://doi.org/10.1101%2F430660.
    10.1101/430660