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Identification

Personal identification

Full name
Maria de Fátima Vieira Ventura

Author identifiers

Ciência ID
3A1D-5A1E-F578

Websites

Education
Degree Classification
1998
Concluded
Farmácia (Doutoramento)
Major in Especialidade: Bioquímica
Universidade de Lisboa, Portugal
"Study on the Mechanisms of Interaction Between Mitochondrial Fatty Acid Beta-oxidation and Oxidativa Phosphorylation" (THESIS/DISSERTATION)
1991
Concluded
Licenciatura em Ciências Farmacêuticas - Opção C - Análises Químico-Biológicas (Licenciatura)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"n/a" (THESIS/DISSERTATION)
16
Affiliation

Teaching in Higher Education

Category
Host institution
Employer
2015 - Current Assistant Professor (University Teacher) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2012 - Current Assistant Professor (University Teacher) Universidade de Lisboa, Portugal
2013 - 2016 Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal
2007 - 2013 Assistant Professor (University Teacher) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2007 - 2007 Assistant (University Teacher) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal

Positions / Appointments

Category
Host institution
Employer
2019/05/25 - Current Organic Unit Sub-director Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP, Portugal
Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP, Portugal

Others

Category
Host institution
Employer
2019/06/01 - Current CHMP representative (alternate) at the Patients and Consumers Working Party (PCWP) Agência Europeia de Medicamentos (European Medicines Agency, EMA), Netherlands
2016/06/01 - Current CHMP representative at the Healthcare Professionals Working Party (HCPWP) European Medicines Agency, Netherlands
2016/03/29 - Current Alternate Portuguese member at the Committee for Medicinal Products for Human Use (CHMP) European Medicines Agency, Netherlands
2010/06/28 - Current Member of the Commission for Medicines Evaluation (Comissão de Avaliação de Medicamentos) Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP, Portugal
2010/05/01 - Current Quality assessor for chemical, biological and biotechnological medicinal products and investigational medicinal products Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP, Portugal
2007/07/01 - Current Researcher from Metabolism & Genetics group, iMed.ULisboa Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2017/03/01 - 2019/05/30 Interim Head of the Scientific Evaluation Unit, Medicines Evaluation Department Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP, Portugal
2007/04/01 - 2012/03/31 Assistant Professor and Researcher at UBMBE/CPM - iMed.UL Universidade de Lisboa Faculdade de Farmácia, Portugal
2002/04/01 - 2007/03/31 Teacher Assistant and Researcher at CPM-UBMBE Universidade de Lisboa Faculdade de Farmácia, Portugal
2001/01/01 - 2002/03/31 Internal Assessor in the Biological and Biotechnological Medicines Area Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP, Portugal
2000/01/01 - 2001/12/31 INFARMED Representative in the Commission for Acquisition of Blood Derivative Medicines Ministério da Saúde, Portugal
2001/01/01 - 2001/09/30 Coordinator of the Operational Unit for Technical and Scientific Medicines Evaluation- DOAMUH Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP, Portugal
1998/04/20 - 2001/04/30 Técnica Superior de Saúde: categoria de Assistente – Ramo Farmácia na Divisão de Medicamentos Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP, Portugal
2000/01/01 - 2001/03/30 Alternate Portuguese Member at the Committe for Proprietary Medicinal Products (CPMP)´s Biotechnological Working Party (BWP) European Medicines Agency, Netherlands
2000/01/01 - 2000/12/31 Portuguese Representative at the Committee for Proprietary Medicinal Products (CPMP)'s “Tradenames Ad-Hoc Review Group” European Medicines Agency, Netherlands
1998/11/17 - 1999/03/31 Teacher Assistant of Cellular Biology from the Pharmaceutical Sciences Degree Egas Moniz Cooperativa de Ensino Superior CRL, Portugal
1998/01/01 - 1998/04/19 Collaborator Centro de Patogénese Molecular, Portugal
1997/10/01 - 1998/04/19 Pharmacist SDC Pharma, Lda, Portugal
1993/10/01 - 1997/10/01 Estudante de Doutoramento Amsterdam UMC Locatie AMC, Netherlands
1991/09/01 - 1993/09/30 Estudante de Doutoramento Centro de Metabolismos e Genética, Faculdade de Farmácia, Universidade de Lisboa, Portugal
1990/10/01 - 1991/06/30 Training Position in Clinical Chemistry Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal
1991/01/01 - 1991/04/30 Private Clinical Chemistry Laboratory (S. João da Talha, Lisboa) Laboratório de Análises Clínicas, Portugal
Projects

Grant

Designation Funders
2018/10 - 2021/09 Understand to treat: Combining in vitro and in silico strategies to explore new therapeutic approaches to the most common mitochondrial fatty acid beta-oxidation disorder (mFAOD)
PTDC/BIA-BQM/29570/2017
Fundação para a Ciência e a Tecnologia
2009/01 - 2012/09 Production of a stable form of human phenylalanine hydroxylase: towards the 3D structure determination. Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
1992 - Current Aminoacidopathies: detection and chemical characterization of the Inborn Errors of the Aminoacids’ Metabolism
project 1A from Line of action 1
Researcher
Centro de Metabolismos e Genética, Faculdade de Farmácia, Universidade de Lisboa, Portugal
INIC - Instituto Nacional de Investigação Ciêntifica
Concluded
1992 - Current Aminoacidopathies: detection and chemical characterization of the Inborn Errors of the Aminoacids¿ Metabolism
project 1A from Line of action 1
INIC - Instituto Nacional de Investigação Ciêntifica
Concluded
1992 - Current Inborn Errors of Metabolism: Aminoacidopathies and Organic Acidurias
PMCT/C/SAU/1540/92
Researcher
Centro de Metabolismos e Genética, Faculdade de Farmácia, Universidade de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010 - 2011 Medium-chain Acyl-CoA Dehydrogenase (MCAD) Deficiency: Functional and Structural Characterisation of Mutant Proteins
SPDM 2010/2011
Principal investigator
Centro de Patogénese Molecular, Portugal
Concluded
Outputs

Publications

Book
  1. Houten, S.M.; Violante, S.; Ventura, F.V.; Wanders, R.J.A.. The Biochemistry and Physiology of Mitochondrial Fatty Acid ß-Oxidation and Its Genetic Disorders. 2016.
    10.1146/annurev-physiol-021115-105045
Journal article
  1. Souto, Eliana; Silva, Gabriela F.; Dias-Ferreira, João; Zielinska, Aleksandra; Ventura, Fátima; Durazzo, Alessandra; Lucarini, Massimo; Novellino, Ettore; Santini, Antonello. "Nanopharmaceutics: Part II - Production scales and clinically compliant production methods". (2020): http://hdl.handle.net/1822/64421.
    10.3390/nano10030455
  2. Souto, Eliana; Silva, Gabriela F.; Dias-Ferreira, João; Zielinska, Aleksandra; Ventura, Fátima; Durazzo, Alessandra; Lucarini, Massimo; Novellino, Ettore; Santini, Antonello. "Nanopharmaceutics: Part IClinical trials legislation and Good Manufacturing Practices (GMP) of nanotherapeutics in the EU". (2020): http://hdl.handle.net/1822/64124.
    10.3390/pharmaceutics12020146
  3. Pelfrene, Eric; Harvey Allchurch, Martin; Ntamabyaliro, Nsengi; Nambasa, Victoria; Ventura, Fátima V.; Nagercoil, Nithyanandan; Cavaleri, Marco. "The European Medicines Agency’s scientific opinion on oral fexinidazole for human African trypanosomiasis". PLOS Neglected Tropical Diseases 13 6 (2019): e0007381. http://dx.doi.org/10.1371/journal.pntd.0007381.
    Published • 10.1371/journal.pntd.0007381
  4. Janeiro, P.; Jotta, R.; Ramos, R.; Florindo, C.; Ventura, F.V.; Vilarinho, L.; Tavares de Almeida, I.; Gaspar, A.. "Follow-up of fatty acid ß-oxidation disorders in expanded newborn screening era". European Journal of Pediatrics (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85059643549&partnerID=MN8TOARS.
    10.1007/s00431-018-03315-2
  5. Bonito, C.A.; Leandro, P.; Ventura, F.V.; Guedes, R.C.. "Insights into Medium-chain Acyl-CoA Dehydrogenase Structure by Molecular Dynamics Simulations". Chemical Biology and Drug Design 88 2 (2016): 281-292. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962748843&partnerID=MN8TOARS.
    10.1111/cbdd.12755
  6. Bonito, C.A.; Nunes, J.; Leandro, J.; Louro, F.; Leandro, P.; Ventura, F.V.; Guedes, R.C.. "Unveiling the Pathogenic Molecular Mechanisms of the Most Common Variant (p.K329E) in Medium-Chain Acyl-CoA Dehydrogenase Deficiency by in Vitro and in Silico Approaches". Biochemistry 55 51 (2016): 7086-7098. http://www.scopus.com/inward/record.url?eid=2-s2.0-85008440769&partnerID=MN8TOARS.
    10.1021/acs.biochem.6b00759
  7. Bonito, C. A.; Leandro, P.; Ventura, F. V.; Guedes, R. C.. "New insights on the molecular mechanisms underlying the medium-chain fatty acid acyl-CoA deficiency (MCADD)". Febs Journal 281 (2014): 358-358. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000359666802292&KeyUID=WOS:000359666802292.
  8. Ventura, F.V.; Leandro, P.; Luz, A.; Rivera, I.A.; Silva, M.F.B.; Ramos, R.; Rocha, H.; et al. "Retrospective study of the medium-chain acyl-CoA dehydrogenase deficiency in Portugal". Clinical Genetics 85 6 (2014): 555-561. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899493496&partnerID=MN8TOARS.
    10.1111/cge.12227
  9. Violante, S.; IJlst, L.; Te Brinke, H.; Koster, J.; De Almeida, I.T.; Wanders, R.J.A.; Ventura, F.V.; Houten, S.M.. "Peroxisomes contribute to the acylcarnitine production when the carnitine shuttle is deficient". Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1831 9 (2013): 1467-1474. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884853475&partnerID=MN8TOARS.
    10.1016/j.bbalip.2013.06.007
  10. Violante, S.; IJlst, L.; Te Brinke, H.; De Almeida, I.T.; Wanders, R.J.A.; Ventura, F.V.; Houten, S.M.. "Carnitine palmitoyltransferase 2 and carnitine/acylcarnitine translocase are involved in the mitochondrial synthesis and export of acylcarnitines". FASEB Journal 27 5 (2013): 2039-2044. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877125588&partnerID=MN8TOARS.
    10.1096/fj.12-216689
  11. Violante, S.; Ijlst, L.; Ruiter, J.; Koster, J.; van Lenthe, H.; Duran, M.; de Almeida, I.T.; et al. "Substrate specificity of human carnitine acetyltransferase: Implications for fatty acid and branched-chain amino acid metabolism". Biochimica et Biophysica Acta - Molecular Basis of Disease 1832 6 (2013): 773-779. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875253711&partnerID=MN8TOARS.
    10.1016/j.bbadis.2013.02.012
  12. Ventura, F.V.; Leandro, P.; Luz, A.; Rivera, I.A.; Silva, M.F.; Ramos, R.; Rocha, H.; et al. "Retrospective study of the medium-chain acyl-CoA dehydrogenase deficiency in Portugal". (2013): http://hdl.handle.net/10400.18/2144.
    doi: 10.1111/cge.12227
  13. Violante, S.; Ijlst, L.; te Brinke, H.; de Almeida, Tavares I.; Wanders, R. J. A.; Ventura, F. V.; Houten, S. M.. "STUDIES ON THE TRANSLOCATION OF ACYLCARNITINES ACROSS THE OUTER MITOCHONDRIAL MEMBRANE: ROLE OF CARNITINE PALMITOYLTRANSFERASE 1A". Journal of Inherited Metabolic Disease 35 (2012): S71-S71. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000307513100244&KeyUID=WOS:000307513100244.
  14. Violante, S.; IJlst, L.; te Brinke, H.; Tavares de Almeida, I; Houten, S.; Ventura, F. V.; Wanders, R. J.. "STUDIES ON THE MITOCHONDRIAL SYNTHESIS AND CELLULAR EXPORT OF ACYLCARNITINES IN MITOCHONDRIAL FATTY ACID BETA-OXIDATION DISORDERS". Journal of Inherited Metabolic Disease 34 (2011): S151-S151. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000309837800263&KeyUID=WOS:000309837800263.
  15. Ventura, F. V.; Lopes, F.; Louro, F.; Luz, A.; Ramos, R.; Rocha, H.; Vilarinho, L.; et al. "THE HUMAN MEDIUM-CHAIN ACYL-COA DEHYDROGENASE P.G377V PROTEIN: A NOVEL DISEASE-CAUSING MUTANT AFFECTING MITOCHONDRIAL FATTY ACID BETA-OXIDATION". Journal of Inherited Metabolic Disease 34 (2011): S152-S152. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000309837800268&KeyUID=WOS:000309837800268.
  16. Violante, S.; IJlst, L.; Denis, S.; de Almeida, I. Tavares; Ventura, F. V.; Wanders, R. J.. "No evidence for the involvement of carnitine palmitoyltransferase 1 transmembrane domains in the formation of an acylcarnitine pore". Febs Journal 277 (2010): 73-74. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000278565100266&KeyUID=WOS:000278565100266.
  17. Violante, S.; Ijlst, L.; Denis, S.; de Almeida, I. Tavares; Houten, S. M.; Ventura, F. V.; Wanders, R. J.. "EVIDENCE AGAINST THE INVOLVEMENT OF CARNITINE PALMITOYLTRANSFERASE 1 TRANSMEMBRANE DOMAINS IN ACYLCARNITINE TRANSPORT ACROSS THE OUTER MITOCHONDRIAL MEMBRANE". Journal of Inherited Metabolic Disease 33 (2010): S58-S58. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000281735000148&KeyUID=WOS:000281735000148.
  18. Violante, S.; IJlst, L.; van Lenthe, H.; de Almeida, I.T.; Wanders, R.J.; Ventura, F.V.. "Carnitine palmitoyltransferase 2: New insights on the substrate specificity and implications for acylcarnitine profiling". Biochimica et Biophysica Acta - Molecular Basis of Disease 1802 9 (2010): 728-732. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954952740&partnerID=MN8TOARS.
    10.1016/j.bbadis.2010.06.002
  19. Violante, S.; IJlst, L.; Tavares de Almeida, I.; Wanders, R. J.; Ventura, F. V.. "Involvement of the carnitine cycle in a potential mitochondrial detoxification pathway: the role of carnitine palmitoyltransferase 2". Febs Journal 276 (2009): 227-227. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000267069900672&KeyUID=WOS:000267069900672.
  20. Ventura, F. V.; Violante, S.; Ruiter, J. P. N.; Ijlst, L.; Silva, M. J.; Houten, S. M.; de Almeida, I. Tavares; Wanders, R. J. A.. "LONG-CHAIN FATTY ACYL-COENZYME A ESTERS". (2009): http://hdl.handle.net/10451/21419.
  21. Violante, S.; Ijlst, L.; Tavares, de Almeida, I; Wanders, R. J.; Ventura, F. V.. "Studies on the substrate specificity of carnitine palmitoyltransferase 2: Implications for acylcarnitine profiling". Journal of Inherited Metabolic Disease 31 (2008): 34-34. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000258656400134&KeyUID=WOS:000258656400134.
  22. Leandro, P; Nascimento, C; Leandro, J; Violante, S; Ventura, F; Silva, MJ; Rivera, I; Tavares de Almeida, I. "The Human Phenylalanine Hydroxylase Protein". (2008): http://hdl.handle.net/10451/21988.
  23. Rivera, I; Silva, MJ; Pinheiro, AS; Faustino, I; Leandro, P; Ventura, F; Tavares de Almeida, I. "Human Pyruvate Dehydrogenase Complex Deficiency". (2008): http://hdl.handle.net/10451/21987.
  24. Violante, S.; Ijlst, L.; Tavares, de Almeida,; Wanders, R. J.; Ventura, F. V.. "Studies on the substrate specificity of carnitine palmitoyltransferase 2". (2008): http://hdl.handle.net/10451/21376.
  25. Tavares de Almeida, I; Silva, MB; Silva, MJM; Leandro, PP; Rivera, IA; Castro, R; Ventura, F; Leite, MS; Santos, HM. "Inborn Errors of Metabolism". (2008): http://hdl.handle.net/10451/21986.
  26. Luz, A.; Violante, S.; Gaspar, A.; Lobo, Antunes M.; Rivera, I. A.; Silva, M. F. B.; Ramos, A.; et al. "Molecular analysis of medium-chain acyl-CoA dehydrogenase deficiency in Portugal". Journal of Inherited Metabolic Disease 31 (2008): 34-34. http://hdl.handle.net/10451/20937.
  27. Ventura, F.V.; Tavares de Almeida, I.; Wanders, R.J.A.. "Inhibition of adenine nucleotide transport in rat liver mitochondria by long-chain acyl-coenzyme A ß-oxidation intermediates". Biochemical and Biophysical Research Communications 352 4 (2007): 873-878. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845443630&partnerID=MN8TOARS.
    10.1016/j.bbrc.2006.11.109
  28. Lobo, Antunes M.; Gaspar, A.; Cabral, A.; Silva, M. F. B.; Ventura, F.; Almeida, I. T.; Eusebio, F.. "Medium chain acyl-CoA dehydrogenase deficiency". (2007): http://hdl.handle.net/10451/21623.
  29. Noronha, M; Gaspar, A; Cabral, A; Silva, MFB; Ventura, F; Almeida, IT. "Medium-chain acyl-CoA dehydrogenase". (2006): http://hdl.handle.net/10451/21999.
  30. Ventura, F.V.; Ruiter, J.; Ijlst, L.; Tavares De Almeida, I.; Wanders, R.J.A.. "Differential inhibitory effect of long-chain acyl-CoA esters on succinate and glutamate transport into rat liver mitochondria and its possible implications for long-chain fatty acid oxidation defects". Molecular Genetics and Metabolism 86 3 (2005): 344-352. http://www.scopus.com/inward/record.url?eid=2-s2.0-27644437646&partnerID=MN8TOARS.
    10.1016/j.ymgme.2005.07.030
  31. Mouro, A; Jorge, A; Leandro, P; Ventura, F; Almeida, ITavares de; Leandro, A; Tavares de Almeida, I. "Heterologous Over-expression of a mutant form of the Human Carnitine/Acylcarnitine Translocase (hCACT)". (2005): http://hdl.handle.net/10451/21763.
  32. Ventura, F; Bravo, AS; Soveral, G; Wanders, RJ; Leandro, P; Tavares de Almeida, I. "Bacterial overexpression of human carnitine acylcarnitine translocase (CACT)". (2004): http://hdl.handle.net/10451/21698.
  33. Ventura, F; Leandro, P; Almeida, ITavares de. "Primary systemic carnitine deficiency". (2003): http://hdl.handle.net/10451/21762.
  34. Tavares de Almeida, I; Ventura, F. "Mitochondrial dysfunction in the fatty acids beta-oxidation defects". (2000): http://hdl.handle.net/10451/22000.
  35. Ventura, F.V.; Costa, C.G.; Struys, E.A.; Ruiter, J.; Allers, P.; Ijlst, L.; Tavares De Almeida, I.; et al. "Quantitative acylcarnitine profiling in fibroblasts using [U-13C] palmitic acid: An improved tool for the diagnosis of fatty acid oxidation defects". Clinica Chimica Acta 281 1-2 (1999): 1-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033037321&partnerID=MN8TOARS.
    10.1016/S0009-8981(98)00188-0
  36. Ventura, F.V.; Ruiter, J.P.N.; IJlst, L.; Tavares De Almeida, I.; Wanders, R.J.A.. "Lactic acidosis in long-chain fatty acid ß-oxidation disorders". Journal of Inherited Metabolic Disease 21 6 (1998): 645-654. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031752337&partnerID=MN8TOARS.
    10.1023/A:1005480516801
  37. Ventura, F.V.; Ijlst, L.; Ruiter, J.; Ofman, R.; Costa, C.G.; Jakobs, C.; Duran, M.; et al. "Carnitine palmitoyltransferase II specificity towards ß-oxidation intermediates: Evidence for a reverse carnitine cycle in mitochondria". European Journal of Biochemistry 253 3 (1998): 614-618. http://www.scopus.com/inward/record.url?eid=2-s2.0-15644369240&partnerID=MN8TOARS.
    10.1046/j.1432-1327.1998.2530614.x
  38. Ventura, F.V.; Costa, C.G.; Ijlst, L.; Dorland, L.; Duran, M.; Jakobs, C.; Tavares De Almeida, I.; Wanders, R.J.A.. "Broad specificity of carnitine palmitoyltransferase II towards long-chain acyl-CoA ß-oxidation intermediates and its practical approach to the synthesis of various long-chain acylcarnitines". Journal of Inherited Metabolic Disease 20 3 (1997): 423-426. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030767942&partnerID=MN8TOARS.
    10.1023/A:1005315003913
  39. Ventura, F.V.; Ruiter, J.P.N.; Ijlst, L.; De Almeida, I.T.; Wanders, R.J.A.. "Inhibitory effect of 3-hydroxyacyl-CoAs and other long-chain fatty acid ß-oxidation intermediates on mitochondrial oxidative phosphorylation". Journal of Inherited Metabolic Disease 19 2 (1996): 161-164. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029925716&partnerID=MN8TOARS.
    10.1007/BF01799419
  40. Ventura, F.V.; Ruiter, J.P.N.; IJlst, L.; Almeida, I.T.; Wanders, R.J.A.. "Inhibition of oxidative phosphorylation by palmitoyl-CoA in digitonin permeabilized fibroblasts: implications for long-chain fatty acid ß-oxidation disorders". BBA - Molecular Basis of Disease 1272 1 (1995): 14-20. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029153718&partnerID=MN8TOARS.
    10.1016/0925-4439(95)00064-B
Activities

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2010 - 2011 PPARs agonists and Fatty Acid Beta-oxidation Regulation
Supervisor
Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2010 - 2011 Medium-chain Acyl-CoA Dehydrogenase Deficiency: Molecular and Biochemical Basis
Supervisor
Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Committee member

Activity description
Role
Institution / Organization
2019/06/01 - Current CHMP representative (alternate) at the Patients and Consumers Working Party (PCWP)
Member
Agência Europeia de Medicamentos (European Medicines Agency, EMA), Netherlands
2019/06/01 - Current Reporte das atividades do Comité de Medicamentos de Uso Humano (CHMP, Committee for Medicinal Products for Human Use)
Member
Agência Europeia de Medicamentos (European Medicines Agency, EMA), Netherlands
2016/06/01 - Current Reporte da atividade do Comité dos Medicamentos de Uso Humano (CHMP, Committee for Medicinal Products for Human Use) da Agência Europeia de Medicamentos
Member
Agência Europeia de Medicamentos (European Medicines Agency, EMA), Netherlands

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2020/12/17 Entrevista Expresso

Interview (tv / radio show)

Program Topic
2021/02/09 - Current É ou não É? - O Grande Debate. Ep. 3 Em busca da imunidade
2021/01/19 - Current Podcast: O dinheiro da Europa descomplicado Como foram negociadas as vacinas contra a covid-19?
2020/12/18 - Current Jornal da Noite Vacina contra a covid-19
Distinctions

Other distinction

2014 Melhor E-Poster
2004 SSIEM Symposium Travelling Scholarship
1992 Prémio Sociedade Lusitana
Ordem dos Farmaceuticos, Portugal