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Renata Sofia Araújo da Silva (RS) has completed her MSc in Toxicology, in 2006, at the University of Aveiro, and her PhD in Pharmaceutical Sciences - Specialty of Toxicology, at the Faculty of Pharmacy of the University of Porto (FFUP), in 2013. She is currently Researcher at UCIBIO -Unidade de Ciências Biomoleculares Aplicadas, Laboratory of Toxicology of FFUP. RS published more than 100 articles in Peer Review International Journals (most of the journals Q1 on their respective fields) and two book chapters, presenting an h-index of 35. She works in the area (s) of Medical and Health Sciences, with an emphasis on Basic Medicine, highlighting the Toxicology, Pharmacology and Pharmacy fields. Her work is focused in the elucidation of the toxicological profile of drugs of abuse, as well as in the field of neurodegeneration and drug discovery, aiming at identifying new disease-modifying drugs with clinical potential for the treatment of neurodegenerative diseases. During the PhD and pos-doc research, RS developed advanced skills and competences in in vitro studies (cell culture of different cell lines, cytotoxicity, metabolism, type of induced cell death, among many others) and in analytical techniques (Flow cytometry, HPLC-UV, UPLC-MS/MS and GC-MS). She already supervised or co-supervised 16 master students and several pre-graduate students , which successfully completed their works. At the present, she supervises or co-supervises 7 FCT-funded PhD students, 2 master students and 1 pre-graduate student. In her Curriculum Vitae , the most frequent terms in the context of scientific and technological production are: P-glycoprotein, Neurodegenerative diseases, Drug discovery, Drug delivery systems, in vitro cytotoxicity studies, drugs of abuse. RS actively participated in two international projects, namely in the TOX-OER project [by developing pedagogical material to an international Massive Open Online Course(MOOC) on Toxicology (https://toxoer.com/)] and in the OEMONOM project (https://portal.faf.cuni.cz/OEMONOM/EN/Home/), both co-financed by the European commission through the Erasmus+ program. She has also participated in several funded R&D scientific projects, 2 of them still ongoing.
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Identificação

Identificação pessoal

Nome completo
Renata Sofia Araújo da Silva

Nomes de citação

  • Silva, Renata

Identificadores de autor

Ciência ID
3912-7C5D-561A
ORCID iD
0000-0001-9962-7548
Researcher Id
I-7439-2015
Scopus Author Id
7201604534

Domínios de atuação

  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
English Advanced (C1) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
French Upper intermediate (B2) Advanced (C1) Upper intermediate (B2) Advanced (C1) Upper intermediate (B2)
Spanish; Castilian Upper intermediate (B2) Upper intermediate (B2) Intermediate (B1) Upper intermediate (B2) Intermediate (B1)
Formação
Grau Classificação
2016/06/23 - 2016/06/23
Concluded
 It´s hip to flip! Turning your class upside-down for learning (Outros)
Universidade do Porto, Portugal
2016/01/14 - 2016/01/15
Concluded
 To engage the students in the classroom (Outros)
Universidade do Porto, Portugal
2015/06 - 2015/06
Concluded
 Intensive Workshop of vocal technique for teachers (Outros)
Universidade do Porto, Portugal
2015/05/06 - 2015/05/06
Concluded
 Moodle na UP (Outros)
Universidade do Porto, Portugal
2015/02/24 - 2015/02/26
Concluded
 LC-MS/MS, Acquity UPLC and Quattro Premier XE models (Outros)
Universidade do Porto Faculdade de Farmácia, Portugal
2007/09 - 2013/12/10
Concluded
 Ciências Farmacêuticas (Doutoramento)
Especialização em Especialidade: Toxicologia
Universidade do Porto Faculdade de Farmácia, Portugal
"Screening of P-Glycoprotein Inducers and Activators as Effective Antidotes Against its Toxic Substrates in Caco-2 Cells. The Example of Paraquat" (TESE/DISSERTAÇÃO)
 Aprovado com distinção
2011/02 - 2011/03
Concluded
 Initiation to flow cytometry (Outros)
Enzifarma, Portugal
2010/01 - 2010/01
Concluded
 Culture of Neuronal cells - basic notions and implementation (Especialização pós-licenciatura)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2007
Concluded
 Mestrado em Toxicologia Analítica, Clínica e Forense (Curso de mestrado (conclusão do curso de especialização))
Especialização em Toxicologia
Universidade do Porto Faculdade de Farmácia, Portugal
 17
2003/10/06 - 2006/11/29
Concluded
 Mestrado em Toxicologia (Mestrado)
Especialização em Toxicologia
Universidade de Aveiro, Portugal
"Development of an HPLC method for the detection of adducts of catecholamines with glutathione in biological samples." (TESE/DISSERTAÇÃO)
 Aprovado
2005/07 - 2005/07
Concluded
 Mass Spectrometry (Outros)
Universidade do Porto Faculdade de Farmácia, Portugal
1996/09/01 - 2003/04/15
Concluded
 Ciências Farmacêuticas (Licenciatura)
Universidade do Porto Faculdade de Farmácia, Portugal
 15
Percurso profissional

Science

Categoria Profissional
Instituição de acolhimento 		Empregador
2024/12/01 - Atual Auxiliary Researcher (Research) Universidade do Porto Faculdade de Farmácia, Portugal
2018/11/01 - 2024/10/31 Contracted Researcher (Research) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2016/07/01 - 2018/10/31 Postdoc (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2014/06/01 - 2016/06/30 Postdoc (Research) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2011/11/01 - 2013/07/31 Researcher (Research) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2007/09/01 - 2011/08/31 Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2006/04/01 - 2007/08/31 Researcher (Research) REQUIMTE, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal

Teaching in Higher Education

Categoria Profissional
Instituição de acolhimento 		Empregador
2020/12/01 - Atual Invited Assistant (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
2014/09 - Atual Invited Assistant Professor (University Teacher) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2014/10/10 - 2018/07/31 Invited Assistant (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2012/09 - 2014/08 Invited Assistant (University Teacher) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
Projetos

Grant

Designação Financiadores
2016/07/01 - 2018/10/31 Design of new inducers/activators of ABC transporters: An innovative strategy to fight Alzheimer's disease
SFRH/BPD/110201/2015
Post-doc Fellow
Universidade do Porto Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2007/09/01 - 2011/08/31 Screening of P-glycoprotein inducers and activators as effective antidotes against its toxic substrates in Caco-2 cells. The example of paraquat
SFRH/BD/29559/2006
PhD Student Fellow
Fundação para a Ciência e a Tecnologia, Portugal
Concluded
2007/01 - 2009/09 OXIDATIVE STRESS IN HEART DISEASE: ROLE OF CATECHOLAMINES
Provided by PTCRIS: 82340
82340
 Fundação para a Ciência e a Tecnologia, I.P.

Contract

Designação Financiadores
2021/01/01 - 2025/12/31 Institute for Health and Bioeconomy
LA/P/0140/2020
10.54499/LA/P/0140/2020
Researcher
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade NOVA de Lisboa, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - 2023/12/31 Applied Molecular Biosciences Unit
UIDP/04378/2020
10.54499/UIDP/04378/2020
Researcher
Universidade NOVA de Lisboa, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2020/01/01 - 2023/12/31 Applied Molecular Biosciences Unit
UIDB/04378/2020
10.54499/UIDB/04378/2020
Researcher
Universidade NOVA de Lisboa, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2014/06/01 - 2016/06/30 Biological studies of New Inducers and activators of ABC Transporters
EQB/LA0006/2014
Post-doc Fellow
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011/11/01 - 2013/07/31 Development and application of P-gp inducers for the prophylaxis and therapeutics of xenobiotics toxicity
PTDC/SAU-OSM/101437/2008
PhD Student Fellow
REQUIMTE, Portugal
Concluded
2006/01 - 2007/12 OXIDATIVE STRESS IN HEART DISEASE: ROLE OF CATECHOLAMINES
Provided by PTCRIS: 55849
55849
Research Fellow
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded

Other

Designação Financiadores
2024/10/15 - Atual New Nanotechnology-Based Cosmetic Products obtained through Advanced Extraction Technologies and Valorization of Marine Biomass
COMPETE2030FEDER-01199900
Researcher
Ongoing
2023/03 - Atual Biomarkers for gadolinium renal injury
2022.08400.PTDC
Researcher
Ongoing
2021 - 2025/01/31 MEDCOR - Antimicrobial and halocromic fiber-based wound dressings using novel pyrimidine-derived molecules
PTDC/CTM-TEX/1213/2020
Researcher
Universidade do Minho, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal

Universidade do Minho Centro de Química, Portugal

Centro de Ciência e Tecnologia Têxtil, Portugal
Ongoing
2021/03/01 - 2024/08/31 Enantioselective ecotoxicity and bioaccumulation of psychoactive substances
PTDC/CTA-AMB/6686/2020
Researcher
Concluded
2020 - 2023/08/31 OEMONOM: Open access Educational Materials On Naturally Occurring Molecules - sources, biological activity and use - ERASMUS+
2020-1-CZ01-KA203-078218
Researcher
Ongoing
2022/09/01 - 2023 Consequences of axonal demyelination for mitochondria biology
Mddemy-GI2-CESPU-2022
Researcher
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
Ongoing
2018/07/02 - 2021/07/01 Antimicrobianos do mar: modelos de agentes inovadores para reverter a resistência a múltiplos fármacos
PTDC/SAU-PUB/28736/2017
Researcher
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2015/09/01 - 2018/02/28 TOX-OER - Learning Toxicology through Open Educational Resources
2015-1-ES01-KA203-015957
Researcher
Concluded
2017/01/01 - 2017/12/31 Multifunctional Nanocarries for smart drug delivery: Nanotoxicology assessments and imaging (MultiNANO@Tox)
MultiNANO@Tox
Researcher
REQUIMTE, Portugal
 REQUIMTE
Concluded
Produções

Publications

Book chapter
  1. Silva, Renata; Remiao, Fernando; Dinis-Oliveira, Ricardo Jorge; Carvalho, Félix; Bastos, Maria de Lourdes. "Toxicocinética". In Toxicologia Fundamental, editado por R. Dinis-Oliveira; F. Carvalho; M.L. Bastos, 9-33. Lidel, Edições Técnicas LDA: Lisboa, 2018.
  2. Dinis-Oliveira, R. J.; Silva, Renata; Carvalho, Félix. "Pesticidas". In Toxicologia Forense, editado por R. Dinis-Oliveira; F. Carvalho; M.L. Bastos, 415-440. Portugal, 2015.
Conference abstract
  1. Gil-martins, E.; Cagide, F.; Borer, A.; Barbosa, D.J.; Fernandes, C.; Remião, F.; Borges, F.; Silva, Renata. Corresponding author: Silva, Renata. "P04-08 Insights into the mechanistic pathways underlying the neurotoxic effects of 2C-I and 25I-NBOMe drugs". 2024.
    10.1016/j.toxlet.2024.07.335
  2. Silva, B.; Costa, I.; Silva, Renata; Cerqueira, F.; Ribeiro, A.; Dantas, D.; Rodrigues, R.; et al. "Antifungal Activity of a New Derivative of 5-Aminoimidazole-4-Carbohydrazonamide - Abstracts from 11th Trends in Medical Mycology -". 2023.
    10.1007/s11046-023-00805-2
  3. Correia, A.; Costa, I.; Silva, Renata; Moreira, J.N.; Lobo, J.M. Sousa; Silva, A. C.. "Brain targeting: optimisation and biocompatibility of valproic acid-loaded nanostructured lipid carriers (VPA-NLC) for nose-to-brain delivery". Trabalho apresentado em 9th International Electronic Conference on Medicinal Chemistry, Basel, 2023.
    doi:10.3390/ECMC2023-15632
  4. Oliveira, R.; Alfenim, A.R.; Soares, P.; Borges, F.; Remião, F.; Fernandes, C.; Silva, R.. "P21-25: Targeting iron dysregulation and oxidative stress for the development of innovative therapeutics against neurodegeneration". 2023.
    10.1016/s0378-4274(23)00832-9
  5. Monteiro, A.R.; Maia, M.; Martins, M.; Sousa, E.; Remião, F.; Silva, R.. "P21-21: Insights into the neuroprotective effects of novel synthetic compounds as potential small molecules for the treatment of Alzheimer's disease". 2023.
    10.1016/s0378-4274(23)00828-7
  6. Ribeiro, A.I.; Silva, B.; Vieira, B.; Alves, C.; Pinto, E.; Cerqueira, F.; Silva, R.; et al. "P05-09: In vitro assessment of the biocompatibility of new halochromic fabrics with promising antifungal activities". 2023.
    10.1016/s0378-4274(23)00505-2
  7. J. Veiga-Matos; D. J. V. A. dos Santos; E. Sousa; M. Prieto Vicente; F. Remião; Silva, Renata. "In silico study of (thio)xanthones-mediated P-glycoprotein activation". Trabalho apresentado em II TOXRUN International Congress, Porto, 2023.
    Published • https://doi.org/10.48797/sl.2023.95
  8. R. Marques-Oliveira; Alfenim, A.R.; P. Soares; Borges, F.; F. Remião; C. Fernandes; Silva, Renata. "New 8-hydroxyquinoline derivatives as promising therapeutic approaches targeting neurodegeneration". Trabalho apresentado em II TOXRUN International Congress, Porto, 2023.
    Published • https://doi.org/10.48797/sl.2023.92
  9. Silva, V.; Benfeito, S.; C. Lima ; Chavarria, D.; T. Gonçalves; I. Costa; F. Remião; F. Borges; Silva, Renata. "3-Hydroxypyridin-4-one based derivatives as promising neuroprotective agents for Parkinson's disease.". Trabalho apresentado em II TOXRUN International Congress, Porto, 2023.
    Published • https://doi.org/10.48797/sl.2023.90
  10. I. Costa; S. Benfeito; V. Silva; F. Cagide; F. Borges; F. Remião; Silva, Renata. "Neuroprotective effects of mitochondria-targeted antioxidants in a Parkinson's disease in vitro model". Trabalho apresentado em II TOXRUN International Congress, Porto, 2023.
    Published • https://doi.org/10.48797/sl.2023.89
  11. A. R. Monteiro; M. Maia; M. Martins; E. Sousa; F. Remião; Silva, Renata. "Alzheimer's disease: the neuroprotective potential of novel synthetic compounds targeting P-glycoprotein". Trabalho apresentado em II TOXRUN International Congress, Porto, 2023.
    Published • https://doi.org/10.48797/sl.2023.88
  12. E. Gil-Martins; F. Cagide; A. Borer; D. J. Barbosa; D. Martins; C. Fernandes; F. Remião; F. Borges; Silva, Renata. "Mechanisms behind the neurotoxicity of 2C-I and 25I-NBOMe drugs". Trabalho apresentado em II TOXRUN International Congress, 2023.
    https://doi.org/10.48797/sl.2023.101
  13. Torres, Joana; Pereira, José Miguel; Silva, Renata; Oliveira, Rita Marques; Peixoto, Andreia Filipa; Lobo, José Manuel Sousa; Silva, Ana Catarina. "Potential of Antioxidant-Loaded Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC) for the Management of Neurodegenerative Diseases". 2022.
    10.3390/ecmc2022-13417
  14. Costa, I.; Benfeito, S.; Cagide, F.; Silva, V.; Borges, F.; Remião, F.; Silva, R.. "New mitochondria-targeted antioxidants as promising drug candidates for the treatment of Parkinson's disease". 2022.
    10.1016/j.toxlet.2022.07.803
  15. Pereira, Florbela; Lourenço, Ana; Aires-de-Sousa, João; Ferreira, Luísa M.; Marques, M. Manuel B.; Sousa, Emília; Branco, Paula S.. "Synthesis and neuroprotection studies of new tricyclic compounds". Trabalho apresentado em 14th Edition of the Nacional Organic Chemistry Meeting and 7th Edition of the Nacional Therapeutic Chemistry Meeting, Caparica, 2022.
    Published • 10.3390/chemproc2022011001
  16. Pedro Soares; R. Marques-Oliveira; Ana Alfenim; Débora Mena; Carlos Fernandes; Fernando Cagide; Renata Silva; et al. "Targeting neuroinflammation and modulating iron dysregulation with innovative multitarget therapeutics for amyotrophic lateral sclerosis. 56ASM--0187". 2022.
    10.1111/eci.13796
  17. Silva, Vera; Benfeito, Sofia; Gil-Martins, Eva; Costa, Inês; Remião, Fernando; Borges, Fernanda; Silva, Renata. "In vitro neuroprotective effects of dua-acting antiparkinsonians". 2022.
    10.51126/revsalus.v4isup.396
  18. Gil-Martins, Eva; Martins, Daniel; Fonseca, Catarina; Remião, Fernando; Borges, Fernanda; Silva, Renata. "In vitro neuro- and hepatotoxic profile of new psychoactive phenethylamines". 2022.
    10.51126/revsalus.v4isup.260
  19. Matos, J.V.; Morales, A.; Silva, R.; Remião, F.; Prieto, M.. "Modulation of P-glycoprotein expression/activity in HK2 cells". 2021.
    Published • 10.1016/s0378-4274(21)00467-7
  20. Gil Martins, E.; Martins, D.; Silva, V.; Fernandes, C.; Remião, F.; Borges, F; Silva, R. "Mechanisms underlying new psychoactive phenethylamines cytotoxicity". 2021.
    10.1016/s0378-4274(21)00472-0
  21. Pinto, M.R.V.; Barreiro, S.; Silva, R.; Remiao, F.; Borges, F.; Fernandes, C.. "Rescuing a troubled tolcapone: nanomedicine on hepatotoxicity fight club". 2021.
    10.1016/s0378-4274(21)00632-9
  22. M. Martins; M. Maia; E. Gil-Martins; L. Gales; F. Remião; M. Pinto; Silva, Renata; E. Sousa. "Towards the development of potential dual GSK-3ß/BACE-1 inhibitors: a strategy to fight Alzheimer's disease". Trabalho apresentado em Congress of European Societies of Toxicology (EUROTOX 2021), 2021.
    Published
  23. V. Silva; Silva, Renata; Gil-Martins, Eva; Emília Sousa; D Resende; F. Remião; Carolina Rocha-Pereira. "Xanthones as potential P-glycoprotein modulators at the intestinal barrier: in vitro and ex vivo studies.". Trabalho apresentado em Toxicology Letters - Abstracts of the 55th Congress of the European Societies of Toxicology (EUROTOX 2019) TOXICOLOGY – SCIENCE PROVIDING SOLUTIONS, 2019.
    https://doi.org/10.1016/j.toxlet.2019.09.002
  24. Gil-Martins, Eva; Barbosa,Daniel José; Sousa, Emília; Resende, Diana; Remião, Fernando; Silva, Renata. "P-glycoprotein modulation by xanthonic derivatives: a strategy to fight Alzheimer's disease.". Trabalho apresentado em Toxicology Letters - Abstracts of the 55th Congress of the European Societies of Toxicology (EUROTOX 2019) TOXICOLOGY SCIENCE PROVIDING SOLUTIONS, 2019.
  25. Pinto, Miguel; Fernandes, Carlos; Gil-Martins, Eva; Silva, Renata; Benfeito, Sofia; Cagide, F; Borges, F; Remião, F. "Bioavailability improvement of a monoamine oxidase-B inhibitor using PEGylated PCL-based nanoparticles.". Trabalho apresentado em Toxicology Letters - Abstracts of the 55th Congress of the European Societies of Toxicology (EUROTOX 2019) TOXICOLOGY SCIENCE PROVIDING SOLUTIONS, 2019.
    https://doi.org/10.1016/j.toxlet.2019.09.002
  26. Pereira, CR; C.I. Ghanem; Silva, Renata; M.D. Araújo; S.G. Monteiro; A.G. Casanova; S. Chhann; et al. "The effects of 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) on P-glycoprotein activity and expression in the rat instestinal mucosa: An ex vivo and in vivo approach.". Trabalho apresentado em Toxicology Letters - ABSTRACTS of the 54th Congress of the European Societies of Toxicology (EUROTOX 2018) TOXICOLOGY OUT OF THE BOX Brussels, Belgium, 2nd – 5th of September, 2018, 2018.
    https://doi.org/10.1016/j.toxlet.2018.07.027
  27. Gil-Martins, Eva; A. Palmeira; H. Carmo; E. Sousa; A. Lemos; M. Pinto; M.D.L. Bastos; F. Remião; Silva, Renata. "P-gp induction and activation as a potential therapeutic approach in intoxications and/or neurological diseases–in vitro and in silico studies". Trabalho apresentado em Toxicology Letters - ABSTRACTS of the 54th Congress of the European Societies of Toxicology (EUROTOX 2018) TOXICOLOGY OUT OF THE BOX Brussels, Belgium, 2nd – 5th of September, 2018, 2018.
    https://doi.org/10.1016/j.toxlet.2018.07.032
  28. Silva, Tiago; R.F. Simões; V. Sardão; P.J. Oliveira; M.J. Valente; Silva, Renata; Remiao, Fernando; Borges, Fernanda. "In vitro cellular and mitochondrial toxicity of tolcapone and related nitrocatechols". Trabalho apresentado em Toxicology Letters - Abstracts of the 52nd Congress of the European Societies of Toxicology (EUROTOX) Fibes Congress Center Seville, Spain, 04th-07th September 2016, 2016.
    https://doi.org/10.1016/j.toxlet.2016.06.1517
  29. Ferreira, A; Ponte, F; Silva, Renata; Pereira, CR; Sousa, Emilia; Pinto, Madalena; Bastos, M; Remiao, Fernando. "1-(Propan-2-ylamino)-4-propoxy-9h-thioxanthen-9-one (TX5), a newly synthetized P-glycoprotein activator: In vivo study and method development and validation for biological samples quantification". Trabalho apresentado em Toxicology Letters - Abstracts of the 52nd Congress of the European Societies of Toxicology (EUROTOX) Fibes Congress Center Seville, Spain, 04th-07th September 2016, 2016.
    https://doi.org/10.1016/j.toxlet.2016.06.1681
  30. Gil-Martins, Eva; Silva, Renata; Palmeira, Andreia; Sousa, Emilia; Carmo, Helena; Pinto, Madalena; Bastos, Maria De Lourdes; et al. "Hit optimization of newly synthetized xanthonic derivatives as P-gycoprotein modulators – In silico and in vitro studies". Trabalho apresentado em Toxicology Letters - Abstracts of the 52nd Congress of the European Societies of Toxicology (EUROTOX) Fibes Congress Center Seville, Spain, 04th-07th September 2016, 2016.
    https://doi.org/10.1016/j.toxlet.2016.06.1709
  31. Valente, M. J.; Araujo, A. M.; Silva, R.; Bastos, M. L.; Carvalho, F.; Guedes de Pinho, P.; Carvalho, M.. "Hepatic oxidative stress induced by methylone and MDPV: A comparison to MDMA". 2015.
    10.1016/j.toxlet.2015.08.765
  32. Silva, R.; Carmo, H.; Vilas-Boas, V.; Barbosa, D. J.; Palmeira, A.; Sousa, E.; Bastos, M. L.; Remiao, F.. "Hypericin-mediated P-glycoprotein induction protects caco-2 cells against paraquat toxicity: In vitro and in silico studies". 2015.
    10.1016/j.toxlet.2015.08.905
  33. Chaves, C.; Silva, R.; Palmeira, A.; Sousa, E.; Pinto, M.; Decleves, X.; Remiao, F.. "Effect of newly synthetized thioxantones on the activity of P-glycoprotein in RBE4 cells: A new approach to minimize the cytotoxicity of xenobiotics". 2015.
    10.1016/j.toxlet.2015.08.773
  34. Remiao, F.; Silva, R.; Vilas-Boas, V.; Carmo, H.; Dinis-Oliveira, R. J.; Carvalho, F.; Lourdes Bastos, M.. "Induction and activation of P-glycoprotein efflux pump as a therapeutic strategy". 2015.
    10.1016/j.toxlet.2015.08.134
  35. Valente, M. J.; Araujo, A. M.; Silva, R.; Bastos, M. L.; Carvalho, F.; Guedes de Pinho, P.; Carvalho, M.. "Is hyperthermia the triggering factor for hepatotoxicity induced by 'bath salts'? An in vitro study using primary cultured rat hepatocytes". 2015.
    10.1016/j.toxlet.2015.08.752
  36. Silva, Renata; Gameiro, Mariline; Sousa, Emilia; Carmo, Helena; Paiva, Mafalda; Palmeira, Andreia; Barbosa, Daniel; et al. "New thioxanthones and dihydroxylated xanthones as P-glycoprotein inducers/activators". 2014.
    10.1016/j.toxlet.2014.06.304
  37. Arbo, Marcelo; Silva, Renata; Barbosa, Daniel; da Silva, Diana Dias; Bastos, Maria de Lourdes; Carmo, Helena. "Piperazine designer drugs are cytotoxic to human neuroblastoma SH-SY5Y cells". 2014.
    10.1016/j.toxlet.2014.06.225
  38. Remiao, Fernando; Silva, Renata; Vilas-Boas, Vania; Barbosa, Daniel Jose; Palmeira, Andreia; Sousa, Emilia; Carvalho, Felix; Bastos, Maria de Lourdes; Carmo, Helena. "P-glycoprotein expression and activity are differently modulated by Colchicine in Caco-2 cells: In vitro and in silico studies". 2013.
    10.1016/j.toxlet.2013.05.401
  39. Remiao, Fernando; Rossato, Luciana Grazziotin; Dallegrave, Eliane; Arbo, Marcelo; Silva, Renata; Ferreira, Rita; Amado, Francisco; et al. "Mitochondrial impairment after mitoxantrone multi-administration to male Wistar rats". 2013.
    10.1016/j.toxlet.2013.05.373
  40. Carvalho, Felix; Valente, Maria Joao; Henrique, Rui; Boas, Vania Vilas; Silva, Renata; Bastos, Maria Lourdes; de Pinho, Paula Guedes; Carvalho, Marcia. "Role of metabolism in cocaine-induced proximal tubular cell damage". 2012.
    10.1016/j.toxlet.2012.03.433
  41. Vilas-Boas, Vania; Silva, Renata; Bastos, Maria de Lourdes; Remiao, Fernando. "Immortalized rat brain endothelial cells are highly resistant to paraquat toxic effect". 2012.
    10.1016/j.toxlet.2012.03.792
  42. Vilas-Boas, Vania; Silva, Renata; Remiao, Fernando. "Rifampicin derivative, Red-Rif, protects against paraquat cytotoxicity in RBE4 cells". 2012.
    10.1016/j.toxlet.2012.03.398
  43. Vilas-Boas, Vania; Silva, Renata; Vieira, Catia; Martins, Ines; Ferreira, Luisa; Branco, Paula; Bastos, Maria de Lourdes; Remiao, Fernando. "Evaluation of rifampicin and derivatives cytotoxic profile in RBE4 cells". 2012.
    10.1016/j.toxlet.2012.03.301
  44. Silva, R.; Vilas-Boas, V.; Carmo, H.; Dinis-Oliveira, R. J.; Carvalho, F.; Bastos, M. L.; Remiao, F.. "P-glycoprotein induction by hypericin protects Caco-2 cells against paraquat toxicity". 2011.
    10.1016/j.toxlet.2011.05.342
  45. Vilas-Boas, V.; Silva, R.; Vieira, C.; Martins, I.; Ferreira, L.; Branco, P.; Remiao, F.. "P-glycoprotein activity assessment in rat brain endothelial cells-A search for new rifampicin-derived p-glycoprotein inducers". 2011.
    10.1016/j.toxlet.2011.05.345
  46. Silva, R.; Carmo, H.; Guedes De Pinho, P.; Dinis-Oliveira, R.; Carvalho, F.; De Lourdes Bastos, M.; Remiao, F.. "The paraquat-induced toxicity is reversed with the co-exposure to doxorubicin in Caco-2 cells". 2010.
    10.1016/j.toxlet.2010.03.389
  47. Houdkova, T.; Silva, R.; Cordeiro-Da-Silva, A.; Carmo, H.; Remiao, F.. "Effect of colchicine on P-glycoprotein expression and activity in Caco2 cells". 2010.
    10.1016/j.toxlet.2010.03.385
  48. Boas, V. Vilas; Martins, A. M.; Silva, R.; Lima, S. A.; Medeiros, R.; Cordeiro-Da-Silva, A.; Remiao, F.. "Influence of aging and prostatic disease in the expression and activity of P-glycoprotein in human lymphocytes". 2010.
    10.1016/j.toxlet.2010.03.387
  49. Grazziotin Rossato, L.; Marisa Costa, V.; Guedes De Pinho, P.; Silva, R.; Carvalho, F.; Carmo, H.; Bastos, M. D. L.; Remiao, F.. "Development of a GC/IP-MS method for simultaneous quantification of para and meta-synephrine in Caco-2 cells". 2010.
    10.1016/j.toxlet.2010.03.926
  50. da Silva, Diana Dias; Silva, Renata; Remiao, Fernando; Carvalho, Felix; Bastos, Maria de Lourdes; Silva, Elisabete; Carmo, Helena. "Assessing combination effects of amphetamine designer drugs". 2009.
    10.1016/j.toxlet.2009.06.242
  51. Silva, Renata; Cordeiro-da-Silva, Anabela; Carvalho, Felix; Bastos, Maria de Lourdes; Carmo, Helena; Remiao, Fernando. "P-glycoprotein induction as a cellular protection tool against xenobiotics toxicity". 2009.
    10.1016/j.toxlet.2009.06.553
  52. Costa, Vera Marisa; Silva, Renata; Tavares, Ludgero Canario; Vitorino, Rui; Amado, Francisco; Carvalho, Felix; Bastos, Maria de Lourdes; et al. "Adrenaline and reactive oxygen species elicit proteome and energetic metabolism modifications in freshly isolated rat cardiomyocytes". 2009.
    10.1016/j.toxlet.2009.06.427
  53. Silva, Renata; Cordeiro-da-Silva, Anabela; Lima, Sofia A. C.; Carvalho, Felix; Bastos, Maria Lourdes; Carmo, Helena; Remiao, Fernando. "Effect of P-Glycoprotein inducers on its expression and activity in Caco-2 cells". 2008.
    10.1016/j.toxlet.2008.06.462
  54. Pontes, Helena; Silva, Renata; Fernandes, Eduarda; Carmo, Helena; Remiao, Fernando; Carvalho, Felix; Bastos, Maria Lourdes. "Ethanol increases MDMA toxicity to primary rat hepatocyte cultures". 2008.
    10.1016/j.toxlet.2008.06.318
  55. Costa, Vera; Silva, Renata; Ferreira, Luisa; Branco, Paula; Carvalho, Felix; Bastos, Maria Lourdes; Carvalho, Rui; Carvalho, Marcia; Remiao, Fernando. "Oxidation process of adrenaline in freshly isolated rat cardiomyocytes: Formation of adrenochrome, quinoproteins and Gsh-adduct". 2007.
    10.1016/j.toxlet.2007.05.189
  56. Silva, Renata; Costa, Vera M.; Boldt, Silvia; Carmo, Helena; Carvalho, Felix; Carvalho, Marcia; Bastos, Maria De Lourdes; Remiao, Fernando. "Validation of a HPLC-ECD method for the detection of adrenaline-GSH adducts in biological samples". 2006.
    10.1016/j.toxlet.2006.06.277
  57. Mergen, Gorkem; Silva, Renata; Ferreira, Luisa M.; Branco, Paula S.; Remiao, Fernando; Carvalho, Felix; Bastos, Maria de Lourdes; Soylemezoglu, Tulin; Carmo, Helena. "Validation of a HPLC-ECD method for the quantification of the highly reactive metabolite of ecstasy, N-methyl-alpha-methyldopamine, in human serum". 2006.
    10.1016/j.toxlet.2006.07.301
  58. Carmo, H.; Brulport, M.; Hermes, M.; Oesch, F.; Silva, R.; Ferreira, L. M.; Branco, P.; et al. "Influence of CYP2D6 polymorphism on 3,4-methylenedioxymethamphetamine ("ecstasy") cytotoxicity". 2006.
    10.1016/j.toxlet.2006.07.272
  59. Silva, R.; Costa, V.; Boldt, S.; Carmo, H.; Carvalho, F.; Carvalho, M.; Carvalho, R.; Bastos, M. Lourdes; Remiao, F.. "Detection of GSH adducts of catechoamines in biological samples". 2005.
Conference paper
  1. Torres, Joana; Pereira, José Miguel; Silva, Renata; Oliveira, Rita Marques; Peixoto, Andreia Filipa; Lobo, José Manuel Sousa; Silva, Ana Catarina. "Potential of Antioxidant-Loaded Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC) for the Management of Neurodegenerative Diseases". 2022.
    10.3390/ecmc2022-13417
  2. Ribeiro, A.; Dantas, D.; Carvalho, F.; Padrão, J.; Silva, R.; Remiao, F.; Pinto, E.; et al. "Synergistic activity of a novel class of azoimidazole dyes with polyvinylpyrrolidone-silver nanoparticles for the development of antibacterial textiles". Trabalho apresentado em 3rd International Congress of Innovative Textiles. ICONTEX 2022, Tekirdag, Turkey, 18-19 May 2022, Tekirdag, 2022.
  3. Fernando Remião; Amélia Veiga; A. Miguel Gomes; Helena Carmo; Silva, Renata; Vera M Costa; Félix Carvalho; Maria de Lourdes Bastos. "Video Lecture Capture (VLC) – Impacto nos resultados da avaliação dos estudantes.". Trabalho apresentado em CNaPPES 2019 - Congr. Nac. Práticas Pedagógicas no Ensino Superior, Santarém, 2019.
    Accepted
  4. Remiao, F.; Rocha-pereira, C.; Silva, Renata; Costa, V.M.; Soares, J.; Casanova, A.G.; Carmo, H.. "TOX-OER MOOC¿: uma ferramenta para o ensino e a aprendizagem". Trabalho apresentado em CNaPPES 2018 - Congr. Nac. Práticas Pedagógicas no Ensino Superior, Braga, 2018.
    Accepted
  5. Sousa, Emília; Lopes, Ana; Martins, Eva; Silva, Renata; Fernandes, Carla; Palmeira, Andreia; Remião, Fernando; Pinto, Madalena. "Studying the influence of stereochemistry in P-gp modulation: case-study with thioxantones.". Trabalho apresentado em Sciforum Electronic Conference Series, 2016.
    10.3390/ecmc-2-a014
Conference poster
  1. Torres, J.; Silva, Renata; Farias, G.; Sousa Lobo, J. M.; Carvalho Ferreira, D.; Silva, A. C.. "Preliminary studies on the development of nanostructured lipid carriers (NLC) co-encapsulated with ibuprofen and zolmitriptan for nose-to-brain delivery". Trabalho apresentado em 3rd Symposium on Alzheimer's Disease: An Update on Pathology and Therapeutics, 2025.
  2. Costa, I.; Martins, M. S.; Barbosa, D. J.; Sousa, M. E.; Silva, Renata. "). Fiscalin Derivatives Exhibit Dual Neuroprotective Activity Against Aß Toxicity and Iron Damage in Alzheimer’s Disease". Trabalho apresentado em 3rd Symposium on Alzheimer's Disease: An Update on Pathology and Therapeutics, 2025.
  3. Gil-Martins, E.; Cagide-Fagín, F.; Borer, A.; Barbosa, D. J.; Fernandes, C.; Remião, F.; Borges, F.; Silva, Renata. "Insights into the mechanistic pathways underlying the neurotoxic effects of 2C-I and 25I-NBOMe drugs.". Trabalho apresentado em 58th Congress of European Societies of Toxicology - EUROTOX, 2024.
  4. Correia, A. C.; Costa, I.; Silva, Renata; Moreira, J. N.; Sousa Lobo, J. M.; Silva, A. C.. "Optimization and evaluation of the biocompatibility of mucoadhesive nanostructured lipid carriers (NLC) for nose-to-brain drug delivery.". Trabalho apresentado em CRS 2024 Annual Meeting and Expo, 2024.
  5. da Fonseca, C.; Malheiro, R.; Silva, J. P.; Remião, F.; Silva, Renata. "Comparative neurotoxicity assessment of four structurally similar synthetic cathinones using a cholinergic neuronal model". Trabalho apresentado em 17th Meeting of young researchers from the University of Porto (IJUP 2024), 2024.
  6. da Fonseca, C.; Malheiro, R.; Remião, F.; Silva, J. P.; Silva, R.; Silva, Renata. Corresponding author: Silva, Renata. "Neurotoxicity evaluation of four structurally similar synthetic cathinones in a cholinergic neuronal model: a comparative analysis.". Trabalho apresentado em III 1H-TOXRUN International Congress 2024, 2024.
  7. Veiga-Matos, J.; dos Santos, D. J. V. A.; Sousa, E.; Morales, A.; Prieto, M.; Remião, F.; Silva, Renata. Corresponding author: Silva, Renata. "Unraveling fiscalin derivatives' interactions with P-glycoprotein: a computational study". Trabalho apresentado em III 1H-TOXRUN International Congress 2024, 2024.
  8. Azevedo, R.; Costa, I.; Maia, M.; Martins, M.; Remiao, F.; Sousa. M. E.; Silva, Renata. Corresponding author: Silva, Renata. "Unveiling the neuroprotective potential of new xanthene derivatives in Parkinson’s disease". Trabalho apresentado em III 1H-TOXRUN International Congress 2024, 2024.
  9. Jéssica Veiga-Matos; Emília Sousa; Ana I. Morales; Marta Prieto; Fernando Remião; Silva, Renata. "Unveiling thioxanthones: an in vitro investigation of P-gp modulation at the kidney level.". Trabalho apresentado em X Congresso Iberoamericano de Ciências Farmacêuticas, 2023.
  10. B. Silva; I. Costa; Silva, Renata; F. Remião; F. Cerqueira; A. Ribeiro; D. Dantas; et al. "Antifungal Activity of a New Derivative of 5-Aminoimidazole-4-Carbohydrazonamide.". Trabalho apresentado em 11th Trends in Medical Mycology (TIMM 2023), 2023.
  11. A.¿I.¿Ribeiro; B.¿Silva; B.¿Vieira; C.¿Alves; E.¿Pinto; F.¿Cerqueira; Silva, Renata; et al. "In vitro assessment of the biocompatibility of new halochromic fabrics with promising antifungal activities". Trabalho apresentado em 57th Congress of the European Societies of Toxicology (EUROTOX 2023), 2023.
  12. A.¿R.¿Monteiro; M.¿Maia; M.¿Martins; E.¿Sousa; F.¿Remião; Silva, Renata. "Insights into the neuroprotective effects of novel synthetic compounds as potential small molecules for the treatment of Alzheimer's disease". Trabalho apresentado em 57th Congress of the European Societies of Toxicology (EUROTOX 2023), 2023.
  13. R.¿Oliveira; A.¿R.¿Alfenim; P.¿Soares; F.¿Borges; F.¿Remião; C.¿Fernandes; Silva, Renata. "Targeting iron dysregulation and oxidative stress for the development of innovative therapeutics against neurodegeneration". Trabalho apresentado em 57th Congress of the European Societies of Toxicology (EUROTOX 2023), 2023.
  14. Ana Borer; Eva Gil-Martins; Fernando Cagide; Fernando Remião; Fernanda Borges; Silva, Renata. "Exploring the neurotoxic effects of 2C-I and 25I-NBOMe". Trabalho apresentado em 16 Meeting of young researchers from the University of Porto (IJUP 2023), 2023.
  15. Rita Marques-Oliveira; Ana Rita Alfenim; Pedro Soares; Fernanda Borges; Fernando Remião; Carlos Fernandes; Silva, Renata. "Study of the neuroprotective effect of 8-hydroxyquinoline derivatives on human neuroblastoma SH-SY5Y cells.". Trabalho apresentado em 16 Meeting of young researchers from the University of Porto (IJUP 2023), 2023.
  16. Ana Rita Monteiro; Miguel Maia; Márcia Martins; Emília Sousa; Fernando Remião; Silva, Renata. "New P-glycoprotein activators as potential small molecules for the treatment of Alzheimer's disease". Trabalho apresentado em 16 Meeting of young researchers from the University of Porto (IJUP 2023),, 2023.
  17. E. Gil-Martins; F. Cagide; A. Borer; Barbosa, D. J.; Martins, D.; C. Fernandes; F. Remião; Borges, F.; Silva, Renata. "Mechanisms behind the neurotoxicity of 2C-I and 25I-NBOMe drugs". Trabalho apresentado em II TOXRUN International Congress, 2023.
  18. A. R. Monteiro; M. Maia; M. Martins; E. Sousa; F. Remião; Silva, Renata. "Alzheimer's disease: the neuroprotective potential of novel synthetic compounds targeting P-glycoprotein". Trabalho apresentado em II TOXRUN International Congress, 2023.
  19. I. Costa; S. Benfeito; V. Silva; F. Cagide; F. Borges; F. Remião; Silva, Renata. "Neuroprotective effects of mitochondria-targeted antioxidants in a Parkinson's disease in vitro model.". Trabalho apresentado em II TOXRUN International Congress, 2023.
    https://doi.org/10.48797/sl.2023.89
  20. V. Silva; S. Benfeito; C. Lima; D. Chavarria; T. Gonçalves; I. Costa; F. Remião; F. Borges; Silva, Renata. "3-Hydroxypyridin-4-one based derivatives as promising neuroprotective agents for Parkinson's disease". Trabalho apresentado em II TOXRUN International Congress, 2023.
    https://doi.org/10.48797/sl.2023.90
  21. R. Marques-Oliveira; A. R. Alfenim; P. Soares; F. Borges; F. Remião; C. Fernandes; Silva, Renata. "New 8-hydroxyquinoline derivatives as promising therapeutic approaches targeting neurodegeneration". Trabalho apresentado em II TOXRUN International Congress, 2023.
    https://doi.org/10.48797/sl.2023.92
  22. J. Veiga-Matos; D. J. V. A. dos Santos; E. Sousa; M. Prieto Vicente; F. Remião; Silva, Renata. "In silico study of (thio)xanthones-mediated P-glycoprotein activation". Trabalho apresentado em II TOXRUN International Congress, 2023.
    https://doi.org/10.48797/sl.2023.95
  23. J. Torres; J.M. Pereira; R. Marques-Oliveira; C. Correia; Silva, Renata; A.F. Peixoto; J.M. Sousa Lobo; A.C. Silva. "Astaxanthin-loaded nanostructured lipid carriers (NLC) for nose-to-brain delivery in the management of neurodegenerative diseases". Trabalho apresentado em 4th European Conference on Pharmaceutics, Marselha, France, 20-21 March 2023, 2023.
  24. A.C. Correia; A.R. Monteiro; Silva, Renata; J.N. Moreira; J.M. Sousa Lobo; A.C. Silva. "Lipid nanoparticles as vehicles for nose-to-brain drug delivery: a strategy to modify pharmacokinetics of drugs targeted to the central nervous system". Trabalho apresentado em 4th European Conference on Pharmaceutics, Marselha, France, 20-21 March 2023, 2023.
  25. J. Torres; J.M. Pereira; I. Costa; R. Marques Oliveira; Silva, Renata; A.F. Peixoto; J.M. Sousa Lobo; A.C. Silva. "Astaxanthin-loaded lipid nanoparticles for nose-to-brain delivery: potential in the management of neurodegenerative diseases". Trabalho apresentado em 2nd Symposium on Alzheimer’s Disease: An Update on Pathology and Therapeutics, Porto, Portugal, 10-11 fevereiro 2023,, 2023.
  26. Joana Torres; Andreia Peixoto; Silva, Renata; José Manuel Sousa Lobo; Ana Catarina Silva. "Preliminary studies on scaling up the production of lipid nanoparticles by ultrasonication technique". Trabalho apresentado em 4th SPLC-CRS Young Scientists Meeting, i3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal, 6-7 fevereiro 2023, 2023.
  27. Joana Torres; J.M. Pereira; R. Marques-Oliveira; Renata Silva; A.F. Peixoto; J.M. Sousa Lobo; A.C. Silva. "Potential of antioxidant-loaded solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the management of neurodegenerative diseases". Trabalho apresentado em 8th International Electronic Conference on Medicinal Chemistry, 2022.
  28. S. Benfeito; C. Fernandes; D. Chavarria; S. Barreiro; F. Cagide; C. Silva; J. Teixeira; et al. "Synthesis and in vitro evaluation of versatile cell-penetrating mitochondriotropic antioxidants.". Trabalho apresentado em XXVI Encontro Galego-Portugués de Química, Santiago de Compostela, Spain, 16th-18th November 2022., 2022.
  29. I. Costa; V. Silva; S. Benfeito; F. Borges; F. Remião; R. Silva. Corresponding author: R. Silva. "New mitochondria-targeted antioxidants as promising drug candidates for the treatment of Parkinson's disease.". Trabalho apresentado em XV IthInternational Congress of Toxicology (IUTOX), 18th-21st September, Maastricht, the Netherlands., 2022.
  30. Eva Gil Martins; F. Cagide-Fagín; Barbosa, Daniel José; Daniel Martins; Carlos Fernandes; Fernando Remião; Fernanda Borges; Renata Silva. "Neurotoxic profile of psychedelic phenethylamine derivatives.". Trabalho apresentado em MedChem22 (X Meeting of the Paul Ehrlich Euro-PhD Network), 2022.
  31. Vera Silva; Sofia Benfeito; Inês Costa; Carla Lima; Daniel Chavarria; Fernando Remião; Fernanda Borges; Renata Silva. "Evaluation of cytotoxic and neuroprotective profile of potential dual-acting ligands for the treatment of Parkinson´s disease". Trabalho apresentado em MedChem 2022 | X Paul Ehrlich EuroPhD Network Meeting, 2022.
  32. Ana Isabel Ribeiro; Daniela Dantas; Renata Silva; Fernando Remião; Eugénia Pinto; Fátima Cerqueira; Alice Dias; Andrea Zille. "HALOCHROMIC PROPERTIES OF A 5-AMINOIMIDAZOLE-4-CARBOXAMIDRAZONE AND ITS APPLICATION TO WOOL". Trabalho apresentado em 21st Autex 2022 Conference. Lodz, Poland, 7-10 June 2022, 2022.
  33. Rodrigues, R.; Dantas, D.; Carvalho, F.; Ribeiro, A.; Zille, A.; Silva, Renata; Remiao, F.. "Electrochemical Characterization of Imidazole-based Carboxamidrazones in Aqueous and Organic Solutions and Structure-Activity Relationship". Trabalho apresentado em VI Encontro em Técnicas de Caraterização e Análise Química, 2022. Braga, Portugal, 3 June 2022, 2022.
  34. Gil-Martins, E.; Martins, D.; Fernando Remiao; Fernanda Borges; Renata Silva. "Neurotoxicity of New Psychoactive Phenethylamine Derivatives". Trabalho apresentado em In Encontro com a Ciência e Tecnologia em Portugal, 2022.
  35. J.M. Pereira; I. Lascasas; J. Torres ; R. Marques-Oliveira; A.F. Peixoto; F. Remião; J.M. Sousa Lobo; A.C. Silva; R. Silva. Corresponding author: R. Silva. "Potential neuroprotective effects of astaxanthin-loaded solid lipid nanoparticles (SLN) against oxidative stress". Trabalho apresentado em Investigação Jovem na Universidade do Porto (IJUP 2022), 2022.
  36. Ribeiro, A; Dantas, D; Carvalho, F; Padrão, J; Silva, Renata; Remião, F; Pinto, E. "Synergistic activity of a novel class of azoimidazole dyes with polyvinylpyrrolidone-silver nanoparticles for the development of antibacterial textiles". Trabalho apresentado em 3rd International Congress of Innovative Textiles. ICONTEX 2022, Tekirdag, Turkey, 18-19 May 2022, 2022.
  37. I. Costa; V. Silva; S. Benfeito; F. Borges; F. Remião; R. Silva. "New mitochondria-targeted antioxidants as potential neuroprotective agents". Trabalho apresentado em 15º Meeting of young researchers from the University of Porto (IJUP 2022), Rectory of the University of Porto, 4-6th May, Porto, Portugal., 2022.
  38. A. R. Monteiro; S. Barreiro; M. Maia; E. Sousa; F. Remião; R. Silva. "A cholinergic model for screening potential compounds for the treatment of Alzheimer’s disease.". Trabalho apresentado em 15º Meeting of young researchers from the University of Porto (IJUP 2022), Rectory of the University of Porto, 4-6th May, Porto, Portugal., 2022.
  39. R. Marques-Oliveira; P. Soares; F. Remião; C. Fernandes; R. Silva. Corresponding author: R. Silva. "New insights in drug discovery for the treatment of Amyotrophic lateral sclerosis.". Trabalho apresentado em 15º Meeting of young researchers from the University of Porto (IJUP 2022), Rectory of the University of Porto, 4-6th May, Porto, Portugal., 2022.
  40. Vera Silva; Sofia Benfeito; Eva Gil-Martins; Inês Costa; Fernando Remião; Fernanda Borges; Renata Silva. "In vitro neuroprotective effects of dual-acting antiparkinsonians". Trabalho apresentado em APCF-TOXRUN International Congress 2022, Porto, Portugal, 2022.
  41. "Modulation of P-glycoprotein expression/activity in HK2 cells.". Trabalho apresentado em Congress of European Societies of Toxicology (EUROTOX 2021), Virtual meeting, 2021.
  42. "Mechanisms underlying new psychoactive phenethylamines cytotoxicity.". Trabalho apresentado em Congress of European Societies of Toxicology (EUROTOX 2021), Virtual meeting, 2021.
  43. "Rescuing a troubled tolcapone: nanomedicine on hepatotoxicity fight club". Trabalho apresentado em Congress of European Societies of Toxicology (EUROTOX 2021), Virtual meeting, 2021.
  44. Renata Silva. "Towards the development of potential dual GSK-3ß/BACE-1 inhibitors: a strategy to fight Alzheimer's disease". Trabalho apresentado em Congress of European Societies of Toxicology (EUROTOX 2021), Virtual meeting, 2021.
  45. "Tricyclic compounds as potential dual BACE-1/GSK3ß inhibitors: synthesis and neuroprotection studies". Trabalho apresentado em Blue Think Conference 2021, 2021.
  46. "Lipid nanoparticles for vaginal delivery of progesterone". Trabalho apresentado em 12th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2021.
  47. "Synthesis, structure elucidation, and neuroprotection studies of a library of compounds with potential neuroprotective properties". Trabalho apresentado em Concurso de Posters Científicos das VI Jornadas da Bioquímica, online meeting, 2021.
  48. Teixeira, Cláudia; Silva, Ana C.; Silva, Renata (3912-7C5D-561A); Lobo, José M. S.. "Optimization of carbamazepine-loaded nanoemulsions for nose-to-brain delivery". Trabalho apresentado em IJUP'21, Encontro de Investigação Jovem da Universidade do Porto, 14ª Edição, 2021.
  49. Martins, Márcia; Maia, Miguel; Silva, Renata; M. M. Pinto, Madalena; Sousa, Emília. "Synthesis of compounds with potential neuroprotective properties.". Trabalho apresentado em Concurso de Pósteres das Olimpíadas Universitárias da Bioquímica - Edição Especial COVID-19, 2021.
  50. A. Correia; C.P. Costa; Silva, Renata; V. Silva; J.M. Sousa Lobo; A.C. Silva. "Pessaries with progesterone-loaded nanostructured lipid carriers (NLC) for prolonged release.". Trabalho apresentado em Virtual Vancouver Nanomedicine Day, 2020.
  51. Solida Long; Diana I. S. P. Resende; Andreia Palmeira; Anake Kijjoa; Artur M. S. Silva; Maria Elizabeth Tiritan; Patrícia Pereira-Terra; et al. "New marine-derived indolymethyl pyrazinoquinazoline alkaloids with promising antimicrobial profiles.". Trabalho apresentado em EFMC-ISMC & EFMC-YMCS - Virtual Poster Session, 2020.
  52. Chavarria, Daniel; Fernandes, Carlos; Silva, Vera; Gil-Martins, Eva; Silva, Renata; Remião, Fernando; Oliveira, Paulo Jorge; Borges, Fernanda. "Design and development of piperine derivatives acting as potent MAO-B inhibitors and mild P-gp inhibitors.". Trabalho apresentado em 4th WG meeting – MuTaLig COST Action 2020. Faculty of Pharmacy, Ege University, 5-6 th March 2020, Izmir, Turkey., 2020.
  53. Resende, Diana I. S. P; Cruz, Bárbara A.; Bousbaa, Hassan; Silva, Renata; Remião, Fernando; Pinto , Madalena M. M.; Sousa, Emília. "Xanthone derivatives as inhibitors of P-glycoprotein and of tumor cell growth: synthesis and biological evaluation.". Trabalho apresentado em 13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT), 15th-17th January 2020, Aveiro, Portugal., 2020.
  54. A.C. Silva; S. Vaz; Silva, Renata; M.H. Amaral; E. Martins; J.M. Sousa Lobo. "In vitro and human in vivo evaluation of the skin hydration potential of vitamin E-loaded lipid nanosystems formulations". Trabalho apresentado em Controlled Release Society Annual Meeting & Exposition, 2019.
  55. Martins, D.; Silva, T.; Fernandes, C.; Soares, P.; Silva, C; Silva, Renata; Gil-Martins, E.; Borges, F.. "Toxicological profile of phenethylamine-based psychoactive drugs.". Trabalho apresentado em Paul Ehrlich Euro-PhD Network & MuTaLig COST Action meeting 2019 (MedChem19 Catanzaro), 13th - 15th June 2019, Catanzaro, Italy., 2019.
  56. Barros Silva, Tiago; Fernandes, Carlos; Sequeira, Lisa; Silva, Vera; Silva, Renata; Soares-da-Silva, Patrício; Borges, Fernanda. "Hydroxypyridin-4-ones are a versatile scaffold to develop copper(II)-chelating COMT inhibitors with neuroprotective properties.". Trabalho apresentado em Paul Ehrlich Euro-PhD Network & MuTaLig COST Action meeting 2019 (MedChem19 Catanzaro), 13th - 15th June 2019, Catanzaro, Italy., 2019.
  57. Cruz, B.A.; Gil-Martins, E.; Silva, Renata; Remião, Fernando. "Polimorfismos da Glicoproteína-P: Implicações Clínicas e Forenses.". Trabalho apresentado em XV IUCS Conference Cycle and In IV Congress of the Portuguese Association of Forensic Sciences, 11th - 12th April 2019, Porto, Portugal., 2019.
  58. Monjane, S.; Santos-Silva, Vera; Gil-Martins, E.; Chavarria, D.; Borges, F.; Silva, Renata; Fernandes, C.. "Descoberta de novas entidades químicas como potenciais moduladores de Glicoproteína-P.". Trabalho apresentado em XV IUCS Conference Cycle and In IV Congress of the Portuguese Association of Forensic Sciences, 11th - 12th April 2019, Porto, Portugal., 2019.
  59. Vaz, S.; Silva, Renata; Amaral, M.H.; Gil-Martins, E.; Sousa Lobo, J.M.; Silva, A.C.. "Biocompatibility and skin hydration potential of vitamin E-loaded lipid nanosystems formulations.". Trabalho apresentado em XII Meeting of young researchers from the University of Porto (IJUP), Rectory of the University of Porto, 13th February 2019, Porto, Portugal., 2019.
  60. Cruz, Bárbara A.; Silva, Renata; Remião, Fernando. "P-glycoprotein modulation: clinical and forensic applications.". Trabalho apresentado em 17th National Congress of Forensic Medicine and Forensic Sciences. 22th – 24th November 2018, Coimbra, Portugal., 2018.
  61. Pereira, C.R.; Ghanem, C.I.; Silva, Renata; Araújo, M.D.; Monteiro, S.G.; Casanova, A.G.; Chhann, S.; et al. "The effects of 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) on P-glycoprotein activity and expression in the rat instestinal mucosa: An ex vivo and in vivo approach.". Trabalho apresentado em 54th European Congress of the European Societies of Toxicology (EUROTOX 2018), 2-5 September 2018, Brussels, Belgium., 2018.
  62. Gil-Martins, Eva; Palmeira, A.; Carmo, H.; Sousa, E.; Lemos, A.; Pinto, M.; Bastos, M.d.L.; Remião, Fernando; Silva, Renata. "P-gp induction and activation as a potential therapeutic approach in intoxications and/or neurological diseases–in vitro and in silico studies.". Trabalho apresentado em 54th European Congress of the European Societies of Toxicology (EUROTOX 2018), 2-5 September 2018, Brussels, Belgium., 2018.
  63. Rocha-pereira, C.; Silva, Renata; Soares, Jorge; Casanova, Alfredo G.; Carmo, Helena; Carvalho, Félix; Bastos, Maria de Lourdes; Remião, Fernando. "TOX-OER MOOC: learning toxicokinetics and liver as target organ of xenobiotics.". Trabalho apresentado em IPAP18 – Salamanca. Innovation in Pharmacy: Advances and Perspectives. 24th – 28th September 2018, Salamanca, Spain., 2018.
  64. Gil-Martins, Eva; Palmeira, Andreia; Sousa, Emília; Resende, Diana; Puthongking, Ploenthip; Bastos, Maria de Lourdes; Carmo, Helena; et al. "Newly synthetized xanthonic derivatives as P-glycoprotein Modulators – in silico and in vitro studies.". Trabalho apresentado em IPAP18 – Salamanca. Innovation in Pharmacy: Advances and Perspectives. 24th – 28th September 2018, Salamanca, Spain., 2018.
  65. Santos-Silva, Vera; Silva, Renata; Gil-Martins, Eva; Sousa, Emília; Resende, Diana; Pinto, Madalena; Bastos, Maria de Lourdes; Rocha-Pereira, Carolina. "Screening of newly synthetized xanthones for potential P-glycoprotein modulation at the intestinal barrier- in vitro and ex vivo studies.". Trabalho apresentado em IPAP18 – Salamanca. Innovation in Pharmacy: Advances and Perspectives. 24th – 28th September 2018, Salamanca, Spain., 2018.
  66. Gil-Martins, E.; Palmeira, Andreia; Sousa, Emília; Lemos, Agostinho; Carmo, Helena; Pinto, Madalena; Bastos, Maria de Lourdes; Remião, Fernando; Silva, Renata. "P-gp induction and activation by newly synthesized xanthonic derivatives as a potential therapeutic approach in intoxications and neurological diseases.". Trabalho apresentado em Italian-Spanish-Portuguese Joint Meeting in Medicinal Chemistry - MedChemSicily2018, 17-20 July 2018, Palermo, Italy., 2018.
  67. Pisoeiro, C.; Gil-Martins, E.; Ferreira, M.U.J.; Remião, Fernando; Silva, Renata. "Newly synthetized derivatives as P-glycoprotein modulators.". Trabalho apresentado em XII IUCS Conference Cycle and III Congress of the Portuguese Association of Forensic Sciences, 24 - 25 May 2018, Porto, Portugal., 2018.
  68. Pinto, Miguel; Fernandes, Carlos; Reis, Joana; Gil-Martins, Eva; Silva, Renata; LÚCIO, MARLENE; Remião, Fernando; Garrido, Jorge; Borges, Fernanda. "Enhancing the bioavailability properties of a potent monoamine oxidase-B inhibitor using a nanotechnological approach.". Trabalho apresentado em 2nd WG meeting of the MuTaLig COST Action CA15135, 15-16th March, 2018, Tenerife, Spain., 2018.
  69. Silva, A. C.; Amaral, M.H.; Eiras F.; Cunha, S.; Silva, Renata; Gil-Martins, Eva; Lobo, J.S.. "Biocompatibility of cutaneous formulations containing lipid nanoparticles.". Trabalho apresentado em 6th FIP Pharmaceutical Sciences World Congress 2017, 21-24 May 2017, Stockholm, Sweden., 2017.
  70. Marta, R.F.; Dinis-Oliveira, R.; Carvalho, F.; Silva, Renata. "Acute human poisoning with a glyphosate-based herbicide: clinical and experimental observations.". Trabalho apresentado em II Congresso da Associação Portuguesa de Ciências Forenses and Jornadas Científicas de Ciências do Instituto Universitário de Ciências da Saúde, 30- 31st March 2017, Porto, Portugal., 2017.
  71. Lopes, A.; Gil-Martins, Eva; Silva, Renata; Fernandes, C.; Palmeira, A.; Remião, Fernando; Pinto, M.M.M.; Sousa, E.. "Importance of stereochemistry and P-gp modulation in drug development: in vitro studies with chiral thioxanthones.". Trabalho apresentado em XIX National Congress of Biochemistry, 8 - 10 December 2016, Guimarães, Portugal., 2016.
  72. Silva, T.; Simões, R.F.; Sardão, V.; Oliveira, P.J.; Silva, Renata; Remião, Fernando; Borges, F.. "In vitro cellular and mitochondrial toxicity of tolcapone and related nitrocatechols.". Trabalho apresentado em 52nd Congress of European Societies of Toxicology (EUROTOX 2016), 4-7 September 2016, Seville, Spain., 2016.
  73. Ferreira, A.; Ponte, F.; Silva, Renata; Rocha-pereira, C.; Sousa, E.; Pinto, M.; Bastos, M.L.; Remião, Fernando. "1-(Propan-2-ylamino)-4-propoxy-9h-thioxanthen-9-one (TX5), a newly synthetized P-glycoprotein activator: In vivo study and method development and validation for biological samples quantification.". Trabalho apresentado em 52nd Congress of European Societies of Toxicology (EUROTOX 2016), 4-7 September 2016, Seville, Spain., 2016.
  74. Gil-Martins, E.; Silva, Renata; Palmeira, A.; Sousa, E.; Carmo, H.; Pinto, M.; Bastos, M.L.; et al. "Hit optimization of newly synthetized xanthonic derivatives as P-gycoprotein modulators: In silico and in vitro studies.". Trabalho apresentado em 52nd Congress of European Societies of Toxicology (EUROTOX 2016), 4-7 September 2016, Seville, Spain., 2016.
  75. Silva, Renata; Palmeira, A.; Carmo, H.; Gil-Martins, E.; Brito, T.; Lemos, A.; Puthongking, P.; et al. "Studies with (thio)xanthones as activators of P-glycoprotein to prevent cytotoxicity induced by xenobiotics.". Trabalho apresentado em EFMC-ISMC 2016, XXIV EFMC International Symposium on Medicinal Chemistry, 28 August - 1 September 2016, Manchester, UK., 2016.
  76. Lopes, A.; Silva, Renata; Fernandes, C.; Palmeira, A.; Piskorska, M.; Remião, Fernando; Pinto, M.; Sousa, E.. "Studying the influence of stereochemistry in P-gp modulation: case-study with newly synthetized thioxantones.". Trabalho apresentado em I Annual Meeting of the Department of Biological Sciences, Faculty of Pharmacy University of Porto, 19th July 2016, Porto, Portugal., 2016.
  77. Gil-Martins, E.; Rodrigues, C.; Palmeira, A.; Sousa, E.; Lemos, A.; Puthongking, P.; Carmo, H.; et al. "P-glycoprotein induction/activation by newly synthetized xanthones with potential therapeutic application.". Trabalho apresentado em I Annual Meeting of the Department of Biological Sciences, Faculty of Pharmacy University of Porto, 19th July 2016, Porto, Portugal., 2016.
  78. Rito, T.; Gil-Martins, E.; Rodrigues, C.; Palmeira, A.; Sousa, E.; Lemos, A.; Puthongking, P.; et al. "Study of the cytotoxicity and potential p-gp modulation of newly synthetized xanthones with therapeutic potential.". Trabalho apresentado em I Annual Meeting of the Department of Biological Sciences, Faculty of Pharmacy University of Porto, 19th July 2016, Porto, Portugal., 2016.
  79. Gil-Martins, E.; Rodrigues, C.; Rito, T.; Palmeira, A.; Sousa, E.; Lemos, A.; Puthongking, P.; et al. "P-glycoprotein induction/activation by newly synthetized xanthones with potential therapeutic application.". Trabalho apresentado em Biologia na Parede, Faculty of Sciences University of Porto, 5th July 2016, Porto, Portugal., 2016.
  80. Gil-Martins, E.; Rodrigues, C.; Silva, Renata; Palmeira, A.; Sousa, E.; Lemos, A.; Puthongking, P.; et al. "P-glycoprotein induction/activation by newly synthetized xanthones with potential therapeutic application.". Trabalho apresentado em Encontro CIÊNCIA ’16 (Encontro com a Ciência e Tecnologia em Portugal), 4 - 6 July 2016, Lisboa, Portugal., 2016.
  81. Lopes, A.; Silva, Renata; Fernandes, C.; Remião, Fernando; Pinto, M.; Sousa, E.. "Chiral Thioxanthones as Promising P-Glycoprotein Modulators.". Trabalho apresentado em 5th Portuguese Young Chemists Meeting (5th PYCheM) and 1st European Young Chemists Meeting (1st EYCheM), 26­-29 April 2016, Guimarães, Portugal., 2016.
  82. Silva, Renata; Palmeira, A.; Carmo, H.; Barbosa, DJ; Gameiro, M.; Sousa, E.; Pinto, M.; Bastos, M.L.; Remião, Fernando. "P-glycoprotein induction by newly synthetized (thio)xanthones prevents Paraquat cytotoxicity.". Trabalho apresentado em 55th Annual Meeting and ToxExpo, March 13–17 2016, NewOrleans, Louisiana, USA., 2016.
  83. Silva, Renata; Carmo, H.; Vilas-Boas, V.; Barbosa, DJ; Palmeira, A.; Sousa, E.; Bastos, M.L.; Remião, Fernando. "Hypericin-mediated P-glycoprotein induction protects caco-2 cells against paraquat toxicity: in vitro and in silico studies.". Trabalho apresentado em 51st Congress of European Societies of Toxicology (EUROTOX 2015), 13-16 September 2015, Porto, Portugal., 2015.
  84. Chaves, C.; Silva, Renata; Palmeira, A.; Sousa, E.; Pinto, M.; Declèves, X.; Remião, Fernando. "Effect of newly synthetized thioxantones on the activity of P-glycoprotein in RBE4 cells: A new approach to minimize the cytotoxicity of xenobiotics.". Trabalho apresentado em 51st Congress of European Societies of Toxicology (EUROTOX 2015), 13-16 September 2015, Porto, Portugal., 2015.
  85. Valente, M.J.; Araújo, A.M.; Silva, Renata; Bastos, M.L.; Carvalho, F.; Guedes de Pinho, P.; Carvalho, M.. "Is hyperthermia the triggering factor for hepatotoxicity induced by ‘bath salts’? An in vitro study using primary cultured rat hepatocytes.". Trabalho apresentado em 51st Congress of European Societies of Toxicology (EUROTOX 2015), 13-16 September 2015, Porto, Portugal., 2015.
  86. Valente, M.J.; Araújo, A.M.; Silva, Renata; Bastos, M.L.; Carvalho, F.; Guedes de Pinho, P.; Carvalho, M.. "Hepatic oxidative stress induced by methylone and MDPV: a comparison to MDMA.". Trabalho apresentado em 51st Congress of European Societies of Toxicology (EUROTOX 2015), 13-16 September 2015, Porto, Portugal., 2015.
  87. Chaves, C.; Silva, Renata; Palmeira, A.; Sousa, E.; Declèves, X.; Remião, Fernando. "Activation of P-glycoprotein and prevention of mitoxantrone’s cytotoxicity in RBE4 cells by innovative thioxanthonic compounds.". Trabalho apresentado em 11th International Conference on Cerebral Vascular Biology (CVB 2015), 6-9 July 2015, Paris, France., 2015.
  88. Silva, Renata; Arbo, M.; Barbosa, D.J.; Dias da Silva, D.; Bastos, M.L.; Carmo, H.. "Piperazine designer drugs are cytotoxic to human neuroblastoma SH-SY5Y cells.". Trabalho apresentado em 50th Congress of European Societies of Toxicology (EUROTOX 2014), 7-10 September 2014, Edinburgh, Scotland., 2014.
  89. Silva, Renata; Gameiro, M.; Sousa, E.; Carmo, H.; Paiva, M.; Palmeira, A.; Barbosa, DJ; Bastos, M.L.; Remião, Fernando. "New thioxanthones and dihydroxylated xanthones as P-glycoprotein inducers/activators.". Trabalho apresentado em 50th Congress of European Societies of Toxicology (EUROTOX 2014), 7-10 September 2014, Edinburgh, Scotland., 2014.
  90. Arbo, M.D; Rossato, L.G.; Silva, Renata; Bastos, M.L.; Carmo, H.. "Piperazine designer drugs impair mitochondrial function in H9c2 cells.". Trabalho apresentado em I Latin American Congress of Clinical and Laboratorial Toxicology, 27-30 April, 2014, Porto Alegre, Brazil., 2014.
  91. Remião, Fernando; Silva, Renata; Vilas-Boas, V.; Barbosa, DJ; Palmeira, A.; Sousa, E.; Carvalho, F.; Bastos, M.L.; Carmo, H.. "P-glycoprotein expression and activity are differently modulated by Colchicine in Caco-2 cells: In vitro and in silico studies.". Trabalho apresentado em 49st Congress of European Societies of Toxicology (EUROTOX 2013), 01-04 September 2013, Interlaken, Switzerland., 2013.
  92. Remião, Fernando; Grazziotin Rossato, L.; Dallegrave, E.; Arbo, M.; Silva, Renata; Ferreira, R.; Amado, F.; et al. "Mitochondrial impairment after mitoxantrone multi-administration to male Wistar rats.". Trabalho apresentado em 49st Congress of European Societies of Toxicology (EUROTOX 2013), 01-04 September 2013, Interlaken, Switzerland., 2013.
  93. Silva, Renata; Vitorino, R.; Carmo, H.; Vilas-Boas, V.; Amado, F.; Bastos, M.L.; Remião, Fernando. "Comparative analysis of two-dimensional polyacrylamide gel electrophoresis (2-DE) and Liquid Chromatography/SDS-PAGE electrophoresis (LC/SDS-PAGE) for the separation and identification of proteins from a nuclear-enriched protein fraction.". Trabalho apresentado em Proteomics Workshop 2012, 4-6 June 2012, Aveiro, Portugal., 2012.
  94. Vilas-Boas, V.; Silva, Renata; Remião, Fernando. "Rifampicin derivative, Red-Rif, protects against paraquat cytotoxicity in RBE4 cells.". Trabalho apresentado em 48st Congress of European Societies of Toxicology (EUROTOX 2012), 17-20 June 2012, Stockholm, Sweden., 2012.
  95. Vilas-Boas, V.; Silva, Renata; Bastos, M.L.; Remião, Fernando. "Immortalized rat brain endothelial cells are highly resistant to paraquat toxic effect.". Trabalho apresentado em 48st Congress of European Societies of Toxicology (EUROTOX 2012), 17-20 June 2012, Stockholm, Sweden., 2012.
  96. Vilas-Boas, V.; Silva, Renata; Vieira, C.; Martins, I.; Ferreira, L.; Branco, P.; Bastos, M.L.; Remião, Fernando. "Evaluation of rifampicin and derivatives cytotoxic profile in RBE4 cells.". Trabalho apresentado em 48st Congress of European Societies of Toxicology (EUROTOX 2012), 17-20 June 2012, Stockholm, Sweden., 2012.
  97. Carvalho, F.; Valente, M.J.; Henrique, R.; Vilas-Boas, V.; Silva, Renata; Bastos, M.L.; Guedes-de-Pinho, P.; Carvalho, M.. "Role of metabolism in cocaine-induced proximal tubular cell damage.". Trabalho apresentado em 48st Congress of European Society of Toxicology (EUROTOX 2012), 17-20 June 2012, Stockholm, Sweden., 2012.
  98. Vilas-Boas, V.; Silva, Renata; Vieira, C.; Martins, I.; Ferreira, L.; Branco, P.; Remião, Fernando. "P-glycoprotein activity assessment in rat brain endothelial cells-A search for new rifampicin-derived p-glycoprotein inducers.". Trabalho apresentado em 47st Congress of European Societies of Toxicology (EUROTOX 2011), 28-31 August 2011, Paris, France, 2011.
  99. Silva, Renata; Vilas-Boas, V.; Carmo, H.; Dinis-Oliveira, R.J.; Carvalho, F.; Bastos, M.L.; Remião, Fernando. "P-glycoprotein induction by hypericin protects Caco-2 cells against paraquat toxicity.". Trabalho apresentado em 47st Congress of European Societies of Toxicology (EUROTOX 2011), 28-31 August 2011, Paris, France, 2011.
  100. Vilas-Boas, V.; Martins, A.M.; Silva, Renata; Lima, S.A.; Medeiros, R.; Cordeiro-Da-Silva, A.; Remião, Fernando. "Influence of aging and prostatic disease in the expression and activity of P-glycoprotein in human limphocytes.". Trabalho apresentado em XII International Congress of Toxicology (IUTOX 2010), 19-23 July 2010, Barcelona, Spain., 2010.
  101. Silva, Renata; Carmo, H.; Guedes de Pinho, P.; Dinis-Oliveira, R.; Carvalho, F.; Bastos, M.L.; Remião, Fernando. "The paraquat-induced toxicity is reversed with the co-exposure to doxorubicin in caco-2 cells.". Trabalho apresentado em XII International Congress of Toxicology (IUTOX 2010), 19-23 July 2010, Barcelona, Spain., 2010.
  102. Faria, H.; Silva, Renata; Bastos, M.L.; Carmo, H.. "Cytotoxicity of gold nanoparticles functionalized with citrate and pentapeptides groups on human hepatoma HEP G2 cells.". Trabalho apresentado em XII International Congress of Toxicology (IUTOX 2010), 19-23 July 2010, Barcelona, Spain., 2010.
  103. Houdkova, T.; Silva, Renata; Cordeiro-da-Silva, A.; Carmo, H.; Remião, Fernando. "Effect of colchicine on P-glycoprotein expression and activity in Caco-2 cells.". Trabalho apresentado em XII International Congress of Toxicology (IUTOX 2010), 19-23 July 2010, Barcelona, Spain., 2010.
  104. Grazziotin Rossato, L.; Costa, V.M.; Guedes-de-Pinho, P.; Silva, Renata; Carvalho, F.; Carmo, H.; Bastos, M.d.L.; Remião, Fernando. "Development of a GC/IP-MS method for simultaneous quantification of para and meta-synephrine in Caco-2 cells.". Trabalho apresentado em XII International Congress of Toxicology (IUTOX 2010), 19-23 July 2010, Barcelona, Spain., 2010.
  105. Houdkova, T.; Silva, Renata; Cordeiro, A.; Carmo, H.; Remião, Fernando. "Effect of colchicine on p-glycoprotein expression and activity in Caco–2 cells.". Trabalho apresentado em 3rd Meeting of young researchers at UP (IJUP 2010), 17-19 February 2010, Porto, Portugal., 2010.
  106. Vilas-Boas, V.; Martins, A.M.; Silva, Renata; Medeiros, R.; Cordeiro-da-Silva, A.; Remião, Fernando. "Expression and activity evaluation of P-glycoprotein in human lymphocytes.". Trabalho apresentado em 3rd Meeting of young researchers at UP (IJUP 2010), 17-19 February 2010, Porto, Portugal., 2010.
  107. Costa, V.M.; Silva, Renata; Tavares, L.C.; Vitorino, R.; Amado, F.; Carvalho, F.; Bastos, M.L.; et al. "Adrenaline and reactive oxygen species elicit proteome and energetic metabolism modifications in freshly isolated rat cardiomyocytes.". Trabalho apresentado em 46st Congress of European Societies of Toxicology (EUROTOX 2009), 13-16 September 2009, Dresden, Germany, 2009.
  108. da Silva, D.D.; Silva, Renata; Remião, Fernando; Carvalho F.; Bastos, M.L.; Silva, E.; Carmo, H.. "Assessing combination effects of amphetamine designer drugs.". Trabalho apresentado em 46st Congress of European Societies of Toxicology (EUROTOX 2009), 13-16 September 2009, Dresden, Germany., 2009.
  109. Silva, Renata; Cordeiro-da-Silva, A.; Carvalho, F.; Bastos, M.L.; Carmo, H.; Remião, Fernando. "P-glycoprotein induction as a cellular protection tool against xenobiotics toxicity.". Trabalho apresentado em 46st Congress of European Societies of Toxicology (EUROTOX 2009), 13-16 September 2009, Dresden, Germany., 2009.
  110. Silva, Renata; Cordeiro-da-Silva, A.; Carvalho, F.; Bastos, M.L.; Carmo, H.; Remião, Fernando. "Exploring therapeutical pathways with an in vitro model of P-gp induction.". Trabalho apresentado em 1st National Meeting on Medicinal Chemistry, 13-15 November 2008, Porto, Portugal., 2008.
  111. Silva, Renata; Cordeiro-da-Silva, A.; Lima, S.A.C.; Carvalho, F.; Bastos, M.L.; Carmo, H.; Remião, Fernando. "Effect of P-Glycoprotein inducers on its expression and activity in Caco-2 cells.". Trabalho apresentado em 45th Congress of European Societies of Toxicology (EUROTOX 2008), 5-8 October 2008, Rhodes, Greece., 2008.
  112. Pontes, H.; Silva, Renata; Fernandes, E.; Carmo, H.; Remião, Fernando; Carvalho, F.; Bastos, M.L.. "Ethanol increases MDMA toxicity to primary rat hepatocyte cultures.". Trabalho apresentado em 45th Congress of European Societies of Toxicology (EUROTOX 2008), 5-8 October 2008, Rhodes, Greece., 2008.
  113. Silva, Renata; Costa, V.M.; Vitorino, R.; Amado, F.; Carvalho, F.; Bastos, M.L.; Carvalho, R.A.; Carvalho, M.; Remião, Fernando. "Effect of adrenaline oxidation process in the protein content of freshly isolated cardiomyocytes.". Trabalho apresentado em ProCura-RNEM meeting, 10-11 November 2007, Aveiro, Portugal., 2007.
  114. Costa, V.M.; Silva, Renata; Amado, F.; Carvalho, F.; Bastos, M.L.; Carvalho, R.A.; Carvalho, M.; Remião, Fernando. "Time dependent activation of transcription factors after a challenge with adrenaline and reactive oxygen species in freshly isolated cardiomyocytes.". Trabalho apresentado em ProCura-RNEM meeting, 10-11 November 2007, Aveiro, Portugal., 2007.
  115. Costa, V.; Silva, Renata; Ferreira, L.; Branco, P.; Carvalho, F.; Bastos, M.L.; Carvalho, R.; Carvalho, M.; Remião, Fernando. "Oxidation process of adrenaline in freshly isolated rat cardiomyocytes: Formation of adrenochrome, quinoproteins and Gsh-adduct.". Trabalho apresentado em 44th Congress of European Societies of Toxicology (EUROTOX 2007), 7-10 October 2007, Amsterdam, The Netherlands., 2007.
  116. Carmo, H.; Brulport, M.; Hermes, M.; Oesch, F.; Silva, Renata; Ferreira, L.M.; Branco, P.S.; et al. "CYP2D6 metabolizing genotype as a risk factor for “Ecstasy”- induced toxicity.". Trabalho apresentado em III Mediterranean Academy of Forensic Sciences Congress, V Latin-American Congresso f Medical Law, III Iberian Congress of Legal Medicine, 21-23 June 2007, Porto, Portugal., 2007.
  117. Silva, Renata; Costa, V.; Boldt, S.; Carmo, H.; Carvalho, F.; Carvalho, M.; Carvalho, R.; Bastos, M.L.; Remião, Fernando. "Validation of a HPLC-ECD method for the detection of adrenaline-GSH adducts in biological samples.". Trabalho apresentado em National congress of Pharmacists, 8-10 March 2007, Lisboa, Portugal., 2007.
  118. Silva, Renata; Costa, V.M.; Boldt, S.; Carmo, H.; Carvalho, F.; Carvalho, M.; Bastos, M.L.; Remiao, F.. "Validation of a HPLC-ECD method for the detection of adrenaline-GSH adducts in biological samples.". Trabalho apresentado em 43nd Congress of European Societies of Toxicology (EUROTOX 2006), 20-24 September 2006, Cavtat, Croatia., 2006.
  119. Carmo, H.; Brulport, M.; Hermes, M.; Oesch, F.; Silva, Renata; Ferreira, L.M.; Branco, P.; et al. "Influence of CYP2D6 polymorphism on 3,4-methylenedioxymethamphetamine (“ecstasy”) cytotoxicity.". Trabalho apresentado em 43nd Congress of European Societies of Toxicology (EUROTOX 2006), 20-24 September 2006, Cavtat, Croatia., 2006.
  120. Mergen, G.; Silva, Renata; Ferreira, L.M.; Branco, P.S.; Remião, Fernando; Carvalho, F.; Bastos, M.L.; Söylemezoglu, T.; Carmo, H.. "Validation of a HPLC-ECD method for the quantification of the highly reactive metabolite of ecstasy, N-methyl-a-methyldopamine, in human serum.". Trabalho apresentado em In 43nd Congress of European Societies of Toxicology (EUROTOX 2006), 20-24 September 2006, Cavtat, Croatia., 2006.
  121. Silva, Renata; Costa, V.; Boldt, S.; Carmo, H.; Carvalho, F.; Carvalho, M.; Carvalho, R.; Bastos, M.L.; Remião, Fernando. "Analysis of Catecholamines GSH Adducts in Biological Samples.". Trabalho apresentado em 4º Encontro do Requimte, rede de Química e Tecnologia, March 31 - April 1 2006, Fátima, Portugal., 2006.
  122. Silva, Renata; Costa, V.M.; Boldt, S.; Carmo, H.; Carvalho, F.; Carvalho, M.; Carvalho, R.; Bastos, M.L.; Remião, Fernando. "Detection of GSH adducts of catecholamines in biological samples.". Trabalho apresentado em 42nd Congress of European Societies of Toxicology (EUROTOX 2005), 11-14 September 2005, Cracow, Poland., 2005.
  123. Bastos, M.L.; Carvalho, F.; Remião, Fernando; Carmo, H.; Carvalho, M.; Capela, J.; Costa, V.; et al. "In vitro evaluation of the mechanisms underlying the toxic effects of xenobiotics.". Trabalho apresentado em Symposium “The Pharmacists in the Health system”, 19 - 20 May 2005, Lisboa, Portugal, 2005.
Journal article
  1. Gil-Martins, Eva; Barbosa, Daniel José; Borges, Fernanda; Remião, Fernando; Silva, Renata. "Toxicodynamic insights of 2C and NBOMe drugs – Is there abuse potential?". Toxicology Reports 14 (2025): 101890. https://doi.org/10.1016/j.toxrep.2025.101890.
    10.1016/j.toxrep.2025.101890
  2. Gil-Martins, Eva; Barbosa, Daniel José; Cagide, Fernando; Remião, Fernando; Borges, Fernanda; Silva, Renata. "Sublethal Concentrations of 2C-I and 25I-NBOMe Designer Drugs Impact Caenorhabditis elegans Development and Reproductive Behavior". International Journal of Molecular Sciences 26 7 (2025): 3039. https://doi.org/10.3390/ijms26073039.
    10.3390/ijms26073039
  3. Sobral, Ana Filipa; Costa, Inês; Teixeira, Vanessa; Silva, Renata; Barbosa, Daniel José. "Molecular Motors in Blood–Brain Barrier Maintenance by Astrocytes". Brain Sciences 15 3 (2025): 279. https://doi.org/10.3390/brainsci15030279.
    10.3390/brainsci15030279
  4. Mendes, Cristina; Maia, Daniela; Dinis-Oliveira, Ricardo Jorge; Remião, Fernando; Silva, Renata; Barbosa, Daniel José. "Synthetic Cathinones Induce Developmental Arrest, Reduce Reproductive Capacity, and Shorten Lifespan in the C. elegans Model". Journal of Xenobiotics 15 1 (2025): 33. https://doi.org/10.3390/jox15010033.
    10.3390/jox15010033
  5. Gil-Martins, Eva; Cagide, Fernando; Borer, Ana; Barbosa, Daniel José; Fernandes, Carlos; Chavarria, Daniel; Remião, Fernando; Borges, Fernanda; Silva, Renata. "The Role of Mitochondrial Dysfunction and Calcium Dysregulation in 2C-I and 25I-NBOMe-Induced Neurotoxicity". Chemico-Biological Interactions (2025): 111425. https://doi.org/10.1016/j.cbi.2025.111425.
    10.1016/j.cbi.2025.111425
  6. Silva, Renata; Sobral, Ana Filipa; Dinis-Oliveira, Ricardo Jorge; Barbosa, Daniel José. "The Link Between Paraquat and Demyelination: A Review of Current Evidence". Antioxidants 13 11 (2024): 1354. https://doi.org/10.3390/antiox13111354.
    10.3390/antiox13111354
  7. Barbosa, Daniel José; Carvalho, Cátia; Costa, Inês; Silva, Renata. "Molecular Motors in Myelination and Their Misregulation in Disease". Molecular Neurobiology (2024): https://doi.org/10.1007/s12035-024-04576-9.
    10.1007/s12035-024-04576-9
  8. Torres, Joana; Silva, Renata; Farias, Gonçalo; Sousa Lobo, José Manuel; Ferreira, Domingos Carvalho; Silva, Ana Catarina. "Enhancing Acute Migraine Treatment: Exploring Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for the Nose-to-Brain Route". Pharmaceutics 16 10 (2024): 1297. https://doi.org/10.3390/pharmaceutics16101297.
    10.3390/pharmaceutics16101297
  9. Correia, A.C.; Costa, I.; Silva, R.; Sampaio, P.; Moreira, J.N.; Sousa Lobo, J.M.; Silva, A.C.. "Design of experiment (DoE) of mucoadhesive valproic acid-loaded nanostructured lipid carriers (NLC) for potential nose-to-brain application". International Journal of Pharmaceutics 664 (2024): 124631. https://doi.org/10.1016/j.ijpharm.2024.124631.
    10.1016/j.ijpharm.2024.124631
  10. Ribeiro, João L.P.; Costa, Inês; Silva, Renata; Lopes, Susana M.M.; Saraiva, Lucília; Pinho e Melo, Teresa M.V.D.. "3-Tetrazolyl-ß-carboline derivatives as potential neuroprotective agents". Bioorganic & Medicinal Chemistry 111 (2024): 117841. https://doi.org/10.1016/j.bmc.2024.117841.
    10.1016/j.bmc.2024.117841
  11. Sobral, Ana Filipa; Cunha, Andrea; Silva, Vera; Gil-Martins, Eva; Silva, Renata; Barbosa, Daniel José. "Unveiling the Therapeutic Potential of Folate-Dependent One-Carbon Metabolism in Cancer and Neurodegeneration". International Journal of Molecular Sciences 25 17 (2024): 9339. https://doi.org/10.3390/ijms25179339.
    10.3390/ijms25179339
  12. Coelho, Maria Miguel; Costa, Inês; de Albuquerque, Ana Carolina Ferreira; Santos Junior, Fernando Martins dos; Silva, Bárbara; Silva, Renata; Fernandes, Carla; Remião, Fernando; Tiritan, Maria Elizabeth. "Milligram scale enantioresolution of promethazine and its main metabolites, determination of their absolute configuration and assessment of enantioselective effects on human SY-SY5Y cells". Journal of Pharmaceutical and Biomedical Analysis 245 (2024): 116152. https://doi.org/10.1016/j.jpba.2024.116152.
    10.1016/j.jpba.2024.116152
  13. Gil-Martins, Eva; Cagide-Fagín, Fernando; Martins, Daniel; Borer, Ana; Barbosa, Daniel José; Fernandes, Carlos; Chavarria, Daniel; et al. "Mechanistic Insights into the Neurotoxicity of 2,5-Dimethoxyphenethylamines (2C) and Corresponding N-(2-methoxybenzyl)phenethylamine (NBOMe) Drugs". Journal of Xenobiotics 14 2 (2024): 772-797. https://doi.org/10.3390/jox14020044.
    10.3390/jox14020044
  14. Costa, Inês; Lopes, Inês; Morais, Mariana; Silva, Renata; Remião, Fernando; Medeiros, Rui; Alves, Luís G.; Pinto, Eugénia; Cerqueira, Fátima. "Disclosing the Antifungal Mechanisms of the Cyclam Salt H4[H2(4-CF3PhCH2)2Cyclam]Cl4 against Candida albicans and Candida krusei". International Journal of Molecular Sciences 25 10 (2024): 5209. https://doi.org/10.3390/ijms25105209.
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  15. Monteiro, Ana Rita; Barbosa, Daniel José; Remião, Fernando; Silva, Renata. "Co-Culture Models: Key Players in In Vitro Neurotoxicity, Neurodegeneration and BBB Modeling Studies". Biomedicines 12 3 (2024): 626. https://doi.org/10.3390/biomedicines12030626.
    10.3390/biomedicines12030626
  16. Ribeiro, Ana Isabel; Dantas, Daniela; Carvalho, Luís Filipe; Padrão, Jorge; Silva, Renata; Remião, Fernando; Pinto, Eugénia; et al. "Synergistic anti-bacterial activity of imidazole-based azo dyes with polyvinylpyrrolidone-coated silver nanoparticles". Coloration Technology (2023): http://dx.doi.org/10.1111/cote.12732.
    10.1111/cote.12732
  17. Jéssica Veiga-Matos; Ana I. Morales; Marta Prieto; Fernando Remião; Renata Silva. Corresponding author: Renata Silva. "Study Models of Drug-Drug Interactions Involving P-Glycoprotein: The Potential Benefit of P-Glycoprotein Modulation at the Kidney and Intestinal Levels". Molecules (2023): https://doi.org/10.3390/molecules28227532.
    10.3390/molecules28227532
  18. Pina Costa, Cláudia; Nižic Nodilo, Laura; Silva, Renata; Martins, Eva; Zadravec, Dijana; Kalogjera, Livije; Nuno Moreira, João; et al. "In situ hydrogel containing diazepam-loaded nanostructured lipid carriers (DZP-NLC) for nose-to-brain delivery: development, characterization and deposition studies in a 3D-printed human nasal cavity model". International Journal of Pharmaceutics 644 (2023): 123345. http://dx.doi.org/10.1016/j.ijpharm.2023.123345.
    10.1016/j.ijpharm.2023.123345
  19. Martins, Daniel; Gil-Martins, Eva; Cagide, Fernando; da Fonseca, Catarina; Benfeito, Sofia; Fernandes, Carlos; Chavarria, Daniel; et al. "Unraveling the In Vitro Toxicity Profile of Psychedelic 2C Phenethylamines and Their N-Benzylphenethylamine (NBOMe) Analogues". Pharmaceuticals 16 8 (2023): 1158. http://dx.doi.org/10.3390/ph16081158.
    10.3390/ph16081158
  20. Joana Torres; Andreia Peixoto; Silva, Renata; José Lobo; Ana Catarina Silva. "Uso intranasal de nanopartículas lipídicas contendo compostos antioxidantes provenientes de bio-resíduos marinhos e o seu potencial no tratamento de doenças neurodegenerativas". Acta Farmacêutica Portuguesa 12 1 (2023): 16-50.
  21. Costa, Inês; Barbosa, Daniel José; Silva, Vera; Benfeito, Sofia; Borges, Fernanda; Remião, Fernando; Silva, Renata. Corresponding author: Silva, Renata. "Research Models to Study Ferroptosis's Impact in Neurodegenerative Diseases". Pharmaceutics 15 5 (2023): 1369. http://dx.doi.org/10.3390/pharmaceutics15051369.
    10.3390/pharmaceutics15051369
  22. Costa, Inês; Barbosa, Daniel José; Benfeito, Sofia; Silva, Vera; Chavarria, Daniel; Borges, Fernanda; Remião, Fernando; Silva, Renata. Corresponding author: Silva, Renata. "Molecular mechanisms of ferroptosis and their involvement in brain diseases". Pharmacology & Therapeutics 244 (2023): 108373. http://dx.doi.org/10.1016/j.pharmthera.2023.108373.
    Published • 10.1016/j.pharmthera.2023.108373
  23. Ribeiro, Ana Isabel; Vieira, Bárbara; Alves, Cátia; Silva, Bárbara; Pinto, Eugénia; Cerqueira, Fátima; Silva, Renata; et al. "Halochromic Silk Fabric as a Reversible pH-Sensor Based on a Novel 2-Aminoimidazole Azo Dye". Polymers 15 7 (2023): 1730. http://dx.doi.org/10.3390/polym15071730.
    Published • 10.3390/polym15071730
  24. Torres, Joana; Pereira, José Miguel; Marques-Oliveira, Rita; Costa, Inês; Gil-Martins, Eva; Silva, Renata; Remião, Fernando; et al. Corresponding author: Silva, Renata. "An In Vitro Evaluation of the Potential Neuroprotective Effects of Intranasal Lipid Nanoparticles Containing Astaxanthin Obtained from Different Sources: Comparative Studies". Pharmaceutics 15 4 (2023): 1035. http://dx.doi.org/10.3390/pharmaceutics15041035.
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  25. Ana Isabel Ribeiro; Bárbara Vieira; Daniela Dantas; Bárbara Silva; Eugénia Pinto; Fátima Cerqueira; Renata Silva; et al. "Synergistic Antimicrobial Activity of Silver Nanoparticles with an Emergent Class of Azoimidazoles". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15030926.
    10.3390/pharmaceutics15030926
  26. Monteiro Ana, R.; Daniel José, Barbosa; Fernando, Remião; Renata, Silva. Corresponding author: Renata, Silva. "Alzheimer's disease: insights and new prospects in disease pathophysiology, biomarkers and disease-modifying drugs". Biochemical Pharmacology (2023): 115522. http://dx.doi.org/10.1016/j.bcp.2023.115522.
    Accepted • 10.1016/j.bcp.2023.115522
  27. Joana Torres; Inês Costa; Andreia F. Peixoto; Renata Silva; José Manuel Sousa Lobo; Ana Catarina Silva. "Intranasal Lipid Nanoparticles Containing Bioactive Compounds Obtained from Marine Sources to Manage Neurodegenerative Diseases". Pharmaceuticals (2023): https://doi.org/10.3390/ph16020311.
    10.3390/ph16020311
  28. Sofia Benfeito; Carlos Fernandes; Daniel Chavarria; Sandra Barreiro; Fernando Cagide; Lisa Sequeira; José Teixeira; et al. "Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks". Journal of Medicinal Chemistry (2023): https://doi.org/10.1021/acs.jmedchem.2c01630.
    10.1021/acs.jmedchem.2c01630
  29. Martins, Alexandra; da Silva, Diana Dias; Silva, Renata; Carvalho, Félix; Guilhermino, Lúcia. "Warmer water, high light intensity, lithium and microplastics: Dangerous environmental combinations to zooplankton and Global Health?". Science of The Total Environment 854 (2023): 158649. http://dx.doi.org/10.1016/j.scitotenv.2022.158649.
    10.1016/j.scitotenv.2022.158649
  30. Dantas, Daniela; Ribeiro, Ana I.; Carvalho, Filipe; Gil-Martins, Eva; Silva, Renata; Remião, Fernando; Zille, Andrea; et al. "Red-shifted and pH-responsive imidazole-based azo dyes with potent antimicrobial activity". Chemical Communications 59 19 (2023): 2791-2794. http://dx.doi.org/10.1039/d3cc00372h.
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  31. Neves, Ana Rita; Freitas-Silva, Joana; Durães, Fernando; Silva, Elisabete R.; Rodrigues, Inês C.; Mergulhão, Filipe; Gomes, Marisa; et al. "Insights into the antimicrobial properties of a cationic steroid and antibiofilm performance in PDMS-based coatings to potentially treat urinary infections". Journal of Materials Chemistry B 11 36 (2023): 8697-8716. http://dx.doi.org/10.1039/d3tb01185b.
    10.1039/d3tb01185b
  32. Remião, Fernando; Carmo, Helena; Gomes, Miguel; Silva, Renata; Costa, Vera Marisa; Carvalho, Félix; Bastos, Maria de Lourdes. "The impact of video lecture capture on student attainment and achievement of intended learning outcomes". Pharmacy Education 22 1 (2022): 843-855. http://dx.doi.org/10.46542/pe.2022.221.843855.
    10.46542/pe.2022.221.843855
  33. Correia, A.C.; Monteiro, A.R.; Silva, R.; Moreira, J.N.; Sousa Lobo, J.M.; Silva, A.C.. "Lipid nanoparticles strategies to modify pharmacokinetics of central nervous system targeting drugs: Crossing or circumventing the blood–brain barrier (BBB) to manage neurological disorders". Advanced Drug Delivery Reviews 189 (2022): 114485. http://dx.doi.org/10.1016/j.addr.2022.114485.
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  34. Martins, Alexandra; da Silva, Diana Dias; Silva, Renata; Carvalho, Félix; Guilhermino, Lúcia. "Long-term effects of lithium and lithium-microplastic mixtures on the model species Daphnia magna: Toxicological interactions and implications to "One Health"". Science of The Total Environment 838 (2022): 155934. http://dx.doi.org/10.1016/j.scitotenv.2022.155934.
    10.1016/j.scitotenv.2022.155934
  35. Pinto, Miguel; Silva, Vera; Barreiro, Sandra; Silva, Renata; Remião, Fernando; Borges, Fernanda; Fernandes, Carlos. "Brain drug delivery and neurodegenerative diseases: Polymeric PLGA-based nanoparticles as a forefront platform". Ageing Research Reviews 79 (2022): 101658. http://dx.doi.org/10.1016/j.arr.2022.101658.
    10.1016/j.arr.2022.101658
  36. Sandra Barreiro; Bárbara Silva; Solida Long; Madalena Pinto; Fernando Remião; Emília Sousa; Renata Silva. "Fiscalin Derivatives as Potential Neuroprotective Agents". Pharmaceutics (2022): https://doi.org/10.3390/pharmaceutics14071456.
    10.3390/pharmaceutics14071456
  37. Castelpietra, Giulio; Knudsen, Ann Kristin Skrindo; Agardh, Emilie E.; Armocida, Benedetta; Beghi, Massimiliano; Iburg, Kim Moesgaard; Logroscino, Giancarlo; et al. "The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Disease Study 2019". The Lancet Regional Health - Europe 16 (2022): 100341. http://dx.doi.org/10.1016/j.lanepe.2022.100341.
    10.1016/j.lanepe.2022.100341
  38. Ana Isabel Ribeiro; Vasyl Shvalya; Uroš Cvelbar; Renata Silva; Rita Marques-Oliveira; Fernando Remião; Helena P. Felgueiras; Jorge Padrão; Andrea Zille. "Stabilization of Silver Nanoparticles on Polyester Fabric Using Organo-Matrices for Controlled Antimicrobial Performance". Polymers (2022): https://doi.org/10.3390/polym14061138.
    10.3390/polym14061138
  39. Nichols, Emma; Steinmetz, Jaimie D; Vollset, Stein Emil; Fukutaki, Kai; Chalek, Julian; Abd-Allah, Foad; Abdoli, Amir; et al. "Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019". The Lancet Public Health 7 2 (2022): e105-e125. http://dx.doi.org/10.1016/s2468-2667(21)00249-8.
    10.1016/s2468-2667(21)00249-8
  40. Adriana Pereira; Maria João Ramalho; Renata Silva; Vera Silva; Rita Oliveira; Ana Catarina Silva; Maria do Carmo Pereira; Joana Loureiro. "Vine Cane Compounds to Prevent Skin Cells Aging through Solid Lipid Nanoparticles". Pharmaceutics (2022): https://www.mdpi.com/1999-4923/14/2/240.
    10.3390/pharmaceutics14020240
  41. Catarina Gonçalves; Maria João Ramalho; Renata Silva; Vera Silva; Rita Marques-Oliveira; Ana Catarina Silva; Maria Carmo Pereira; Joana A. Loureiro. "Lipid Nanoparticles Containing Mixtures of Antioxidants to Improve Skin Care and Cancer Prevention". Pharmaceutics (2021): https://doi.org/10.3390/pharmaceutics13122042.
    10.3390/pharmaceutics13122042
  42. C.P. Costa; S. Cunha; J.N. Moreira; R. Silva; E. Gil-Martins; V. Silva; L. Azevedo; et al. "Quality by design (QbD) optimization of diazepam-loaded nanostructured lipid carriers (NLC) for nose-to-brain delivery: Toxicological effect of surface charge on human neuronal cells". International Journal of Pharmaceutics 607 (2021): 120933-120933. https://doi.org/10.1016/j.ijpharm.2021.120933.
    10.1016/j.ijpharm.2021.120933
  43. Martins, M.; Maia, M.; Gil-Martins, E.; Gales, L.; Remião, F.; Pinto, M; Silva, R.; Sousa, E.. "Towards the development of potential dual GSK-ß/BACE-1 inhibitors: a strategy to fight Alzheimer's disease". Toxicology Letters 350 (2021): S110-S111. http://dx.doi.org/10.1016/s0378-4274(21)00507-5.
    10.1016/s0378-4274(21)00507-5
  44. Francesco Mesiti; Alexandra Gaspar; Daniel Chavarria; Annalisa Maruca; Roberta Rocca; Eva Gil Martins; Sandra Barreiro; et al. "Mapping Chromone-3-Phenylcarboxamide Pharmacophore: Quid Est Veritas?". Journal of Medicinal Chemistry (2021): https://doi.org/10.1021/acs.jmedchem.1c00510.
    10.1021/acs.jmedchem.1c00510
  45. Cláudia Pina Costa; Sandra Barreiro; João Nuno Moreira; Renata Silva; Hugo Almeida; José Manuel Sousa Lobo; Ana Catarina Silva. "In Vitro Studies on Nasal Formulations of Nanostructured Lipid Carriers (NLC) and Solid Lipid Nanoparticles (SLN)". Pharmaceuticals (2021): https://doi.org/10.3390/ph14080711.
    10.3390/ph14080711
  46. Fernando Durães; Andreia Palmeira; Bárbara Cruz; Joana Freitas-Silva; Nikoletta Szemerédi; Luís Gales; Paulo Martins da Costa; et al. "Antimicrobial Activity of a Library of Thioxanthones and Their Potential as Efflux Pump Inhibitors". Pharmaceuticals 14 6 (2021): 572-572. https://doi.org/10.3390/ph14060572.
    10.3390/ph14060572
  47. Silva, Vera; Gil-Martins, Eva; Silva, Bárbara; Rocha-Pereira, Carolina; Sousa, Maria Emília; Remião, Fernando; Silva, Renata. "Xanthones as P-glycoprotein modulators and their impact on drug bioavailability". Expert Opinion on Drug Metabolism & Toxicology 17 4 (2021): 441-482. http://dx.doi.org/10.1080/17425255.2021.1861247.
    10.1080/17425255.2021.1861247
  48. Silva, Bárbara; Palmeira, Andreia; Silva, Renata; Fernandes, Carla; Guedes de Pinho, Paula; Remião, Fernando. "S-(+)-Pentedrone and R-(+)-methylone as the most oxidative and cytotoxic enantiomers to dopaminergic SH-SY5Y cells: Role of MRP1 and P-gp in cathinones enantioselectivity". Toxicology and Applied Pharmacology 416 (2021): 115442. http://dx.doi.org/10.1016/j.taap.2021.115442.
    10.1016/j.taap.2021.115442
  49. Krambeck, Karolline; Silva, Vera; Silva, Renata; Fernandes, Carlos; Cagide, Fernando; Borges, Fernanda; Santos, Delfim; et al. "Design and characterization of Nanostructured lipid carriers (NLC) and Nanostructured lipid carrier-based hydrogels containing Passiflora edulis seeds oil". International Journal of Pharmaceutics (2021): 120444. http://dx.doi.org/10.1016/j.ijpharm.2021.120444.
    10.1016/j.ijpharm.2021.120444
  50. Correia, A.; Costa, C.P.; Silva, V.; Silva, R.; Lobo, J.M. Sousa; Silva, A.C.. "Pessaries containing nanostructured lipid carriers (NLC) for prolonged vaginal delivery of progesterone". European Journal of Pharmaceutical Sciences 153 (2020): 105475. http://dx.doi.org/10.1016/j.ejps.2020.105475.
    10.1016/j.ejps.2020.105475
  51. Rocha-Pereira, Carolina; Ghanem, Carolina Inés; Silva, Renata; Casanova, Alfredo G.; Duarte-Araújo, Margarida; Gonçalves-Monteiro, Salomé; Sousa, Emília; de Lourdes Bastos, Maria; Remião, Fernando. "Corrigendum to "P-Glycoprotein activation by 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) in rat distal ileum: Ex vivo and in vivo studies" [Toxicology and Applied Pharmacology 386 (2020) 114832]". Toxicology and Applied Pharmacology 404 (2020): 115168. http://dx.doi.org/10.1016/j.taap.2020.115168.
    10.1016/j.taap.2020.115168
  52. Martins, Márcia; Silva, Renata; M. M. Pinto, Madalena; Sousa, Emília; Márcia Martins; Renata Silva; Madalena M. M. Pinto; Emília Sousa. "Marine Natural Products, Multitarget Therapy and Repurposed Agents in Alzheimer's Disease". Pharmaceuticals 13 9 (2020): 242-242. http://dx.doi.org/10.3390/ph13090242.
    10.3390/ph13090242
  53. Silva, Vera; Gil-Martins, Eva; Rocha-Pereira, Carolina; Lemos, Agostinho; Palmeira, Andreia; Puthongking, Ploenthip; Sousa, Emília; et al. "Oxygenated xanthones as P-glycoprotein modulators at the intestinal barrier: in vitro and docking studies". Medicinal Chemistry Research 29 6 (2020): 1041-1057. http://dx.doi.org/10.1007/s00044-020-02544-1.
    10.1007/s00044-020-02544-1
  54. Gil-Martins, Eva; Barbosa, Daniel José; Silva, Vera; Remião, Fernando; Silva, Renata. "Dysfunction of ABC transporters at the blood-brain barrier: Role in neurological disorders". Pharmacology & Therapeutics (2020): 107554. http://dx.doi.org/10.1016/j.pharmthera.2020.107554.
    10.1016/j.pharmthera.2020.107554
  55. Bárbara Silva; Renata Silva; Carla Fernandes; Paula Guedes de Pinho; Fernando Remião. "Enantioselectivity on the absorption of methylone and pentedrone using Caco-2 cell line: Development and validation of an UHPLC method for cathinones quantification". Toxicology and Applied Pharmacology (2020): https://doi.org/10.1016/j.taap.2020.114970.
    10.1016/j.taap.2020.114970
  56. Rocha-Pereira, Carolina; Ghanem, Carolina I.; Silva, Renata; Casanova, Alfredo G.; Duarte-Araújo, Margarida; Gonçalves-Monteiro, Salomé; Sousa, Emília; Bastos, Maria de Lourdes; Remião, Fernando. "P-glycoprotein activation by 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) in rat distal ileum: ex vivo and in vivo studies". Toxicology and Applied Pharmacology 386 (2020): 114832. http://dx.doi.org/10.1016/j.taap.2019.114832.
    10.1016/j.taap.2019.114832
  57. Chavarria, Daniel; Fernandes, Carlos; Silva, Vera; Silva, Catia; Gil-Martins, Eva; Soares, Pedro; Silva, Tiago; et al. "Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies". European Journal of Medicinal Chemistry 185 (2020): 111770. http://dx.doi.org/10.1016/j.ejmech.2019.111770.
    10.1016/j.ejmech.2019.111770
  58. Vaz, S.; Silva, R.; Amaral, M.H.; Martins, E.; Sousa Lobo, J.M.; Silva, A.C.. "Corrigendum to "Evaluation of the biocompatibility and skin hydration potential of vitamin E-loaded lipid nanosystems formulations: In vitro and human in vivo studies" [Colloid Surfaces B: Biointerfaces 179 (2019) 242¿249]". Colloids and Surfaces B: Biointerfaces 185 (2020): 110593. http://dx.doi.org/10.1016/j.colsurfb.2019.110593.
    10.1016/j.colsurfb.2019.110593
  59. Long, Solida; Resende, Diana I. S. P.; Palmeira, Andreia; Kijjoa, Anake; Silva, Artur M. S.; Tiritan, Maria Elizabeth; Pereira-Terra, Patrícia; et al. "New marine-derived indolymethyl pyrazinoquinazoline alkaloids with promising antimicrobial profiles". RSC Advances 10 52 (2020): 31187-31204. http://dx.doi.org/10.1039/d0ra05319h.
    10.1039/d0ra05319h
  60. Silva, Renata. "Histological and toxicological evaluation, in rat, of a P-glycoprotein inducer and activator: 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5).". EXCLI Journal 18 (2019): 697-722. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785774/.
    Published
  61. Miguel Pinto; Carlos Fernandes; Eva Martins; Renata Silva; Sofia Benfeito; Fernando Cagide; Ricardo F. Mendes; et al. "Boosting Drug Discovery for Parkinson’s: Enhancement of the Delivery of a Monoamine Oxidase-B Inhibitor by Brain-Targeted PEGylated Polycaprolactone-Based Nanoparticles". Pharmaceutics (2019): https://doi.org/10.3390/pharmaceutics11070331.
    10.3390/pharmaceutics11070331
  62. Vaz, S.; Silva, R.; Amaral, M.H.; Martins, E.; Sousa Lobo, J.M.; Silva, A.C.. "Evaluation of the biocompatibility and skin hydration potential of vitamin E-loaded lipid nanosystems formulations: In vitro and human in vivo studies". Colloids and Surfaces B: Biointerfaces 179 (2019): 242-249. http://dx.doi.org/10.1016/j.colsurfb.2019.03.036.
    10.1016/j.colsurfb.2019.03.036
  63. Moreira, Fernando X; Carmo, Helena; Melo, Armindo; André, Maria B; Silva, Renata; Azevedo, Zélia; Bastos, Maria L; de Pinho, Paula G. "The Use of Feathers from Racing Pigeons for Doping Control Purposes". Journal of Analytical Toxicology 43 4 (2019): 307-315. http://dx.doi.org/10.1093/jat/bky088.
    10.1093/jat/bky088
  64. Benfeito, S.; Oliveira, C.; Fernandes, C.; Cagide, F.; Teixeira, J.; Amorim, R.; Garrido, J.; et al. "Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction". European Journal of Medicinal Chemistry 167 (2019): 525-545. http://dx.doi.org/10.1016/j.ejmech.2019.01.055.
    10.1016/j.ejmech.2019.01.055
  65. Eva Alexandra Gil Martins; Vera Silva; Agostinho Lemos; Andreia Palmeira; Ploenthip Puthongking; E Sousa; Carolina Rocha-Pereira; et al. "Newly Synthesized Oxygenated Xanthones as Potential P-Glycoprotein Activators: In Vitro, Ex Vivo, and In Silico Studies". Molecules (2019): http://www.mdpi.com/1420-3049/24/4/707.
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  66. Fernandes C; Martins CAU; Fonseca A; Nunes R; Matos MJ; Silva R; Garrido J; et al. "PEGylated PLGA nanoparticles as a smart carrier to increase the cellular uptake of a coumarin-based monoamine oxidase B inhibitor.". ACS applied materials & interfaces (2018): http://europepmc.org/abstract/med/30352150.
    10.1021/acsami.8b17224
  67. Fernando X. Moreira; Renata Silva; Maria B. André; Paula G. de Pinho; Maria L. Bastos; João Ruivo; Patrícia Ruivo; Helena Carmo. "Quantification of doping compounds in faecal samples from racing pigeons, by liquid chromatography-tandem mass spectrometry". Journal of Chromatography B 1089 (2018): 33-42. https://doi.org/10.1016/j.jchromb.2018.05.004.
    10.1016/j.jchromb.2018.05.004
  68. Lopes A; Martins E; Silva R; Pinto MMM; Remião F; Sousa E; Fernandes C. "Chiral Thioxanthones as Modulators of P-glycoprotein: Synthesis and Enantioselectivity Studies.". Molecules (Basel, Switzerland) (2018): http://europepmc.org/abstract/med/29534440.
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  71. Ana Filipa Ferreira; Filipa Ponte; Renata Silva; Carolina Rocha-Pereira; Emília Sousa; Madalena Pinto; Maria de Lourdes Bastos; Fernando Remião. "Quantification of 1-(propan-2-ylamino)-4-propoxy-9H -thioxanthen-9-one (TX5), a newly synthetized P-glycoprotein inducer/activator, in biological samples: method development and validation". Biomedical Chromatography (2017): https://doi.org/10.1002%2Fbmc.3802.
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    Published
Journal issue
  1. Renata Silva; Daniel J Barbosa. "New Insights on Drug Design, Delivery and Targeting in Neurodegeneration". Pharmaceutics (2023): https://www.mdpi.com/journal/pharmaceutics/special_issues/drug_neurodegeneration.
    Invited editor
  2. Barbosa, Daniel Jose; Renata Silva. "Molecular and Cellular Advances on Drug Discovery, Pharmacology and Toxicology". Medicina (2022): https://www.mdpi.com/journal/medicina/special_issues/drug_discovery_pharmacology_and_toxicology.
    Coeditor
Thesis / Dissertation
  1. Renata Sofia Araújo da Silva. "Screening of P-Glycoprotein Inducers and Activators as Effective Antidotes Against its Toxic Substrates in Caco-2 Cells. The Example of Paraquat". PhD, 2013. https://repositorio-aberto.up.pt/handle/10216/71855.
  2. Silva, Renata Sofia Araújo da. "Desenvolvimento de uma metodologia de HPLC para a detecção de aductos das catecolaminas com a GSH em amostras biológicas". Master, 2006. http://hdl.handle.net/10773/712.

Intellectual property

Provisional application for patent
  1. 2023. "Tricyclic compounds and uses thereof".
    Protected
Atividades

Oral presentation

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2025/02/07 In vitro neurotoxicity of synthetic cathinones in a neuritogenesis model 55th Annual Meeting of the Portuguese Pharmacology Society, 43rd Meeting of Clinical Pharmacology and 24th Meeting of Toxicology
Faculty of Medicine, University of Porto (Porto, Portugal)
2025/02/07 Thioxanthonic derivatives-mediated P-glycoprotein activation/induction: a potential protective strategy against cisplatin-induced nephrotoxicity 55th Annual Meeting of the Portuguese Pharmacology Society, 43rd Meeting of Clinical Pharmacology and 24th Meeting of Toxicology
Faculty of Medicine, University of Porto (Porto, Portugal)
2025/02/06 Innovative edaravone derivatives: a promising therapeutic approach for amyotrophic lateral sclerosis. 55th Annual Meeting of the Portuguese Pharmacology Society, 43rd Meeting of Clinical Pharmacology and 24th Meeting of Toxicology
Faculty of Medicine, University of Porto (Porto, Portugal)
2025/02/05 Adrenergic receptors increase cell viability of glioblastoma cell lines through non-canonical signaling involving adrenoceptor internalization 55th Annual Meeting of the Portuguese Pharmacology Society, 43rd Meeting of Clinical Pharmacology and 24th Meeting of Toxicology
Faculty of Medicine, University of Porto (Porto, Portugal)
2024/02/07 Thioxanthones-mediated P-glycoprotein modulation at the kidney level: a comprehensive analysis through in silico and in vitro studies 54th Annual Meeting of the Portuguese Pharmacology Society, 42nd Meeting of Clinical Pharmacology and 23rd Meeting of Toxicology
NOVA Medical School | Faculdade de Ciências Médicas (Lisbon, Portugal)
2023/06/29 (Thio)xanthones-mediated P-glycoprotein activation: an in silico study Jornadas de Toxicología Españolas e Iberoamericanas 2023
Asociación Española de Toxicología (AETOX) INSTITUTO DE CIENCIAS FORENSES-USC (Santiago de Compostela, Spain)
2023/05/11 New mitochondria-targeted hydroxycinnamic and hydroxybenzoic acids derivatives as innovative agents for the treatment of Parkinson's disease. 16 Meeting of young researchers from the University of Porto (IJUP 2023)
University of Porto (Porto, Portugal)
2022/11 Tricyclic compounds derivatives as new potential neuroprotective agents XXVI Encontro Galego-Portugués de Química
(Santiago de Compostela, Spain)
2022/07/08 Targeting neuroinflammation and modulating iron dysregulation with innovative multitarget therapeutics for amyotrophic lateral sclerosis. European Society of Clinical Investigation - 56th annual scientific meeting
European Society of Clinical Investigation (Bari, Italy)
2022/05/05 Potential of astaxanthin-loaded nanostructured lipid carriers (NLC) for the management of neurological diseases. Investigação Jovem na Universidade do Porto (IJUP 2022)
Universidade do Porto (Porto, Portugal)
2022/04/08 In vitro neuro- and hepatotoxic profile of new psychoactive phenethylamines. APCF-TOXRUN International Congress 2022
TOXRUN (Porto)
2022/04 Synthesis and neuroprotection studies of new tricyclic compounds Flash oral communication presented at the 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting
(Caparica, Portugal)
2021/07 Optimization of diazepam-loaded nanostructured lipid carriers (NLC) for nose-to-brain delivery: toxicological effect of surface charge on human neuronal cells Controlled Release Society, Virtual Annual Meeting & Exposition - On-Demand Talk - 3572015
Virtual Annual Meeting & Exposition
2021/05/19 Towards the discovery of small molecules with potential neuroprotective properties 7th Portuguese Young Chemists Meeting, online meeting
Portuguese Young Chemists group from the Portuguese Society of Chemistry (Bragança, Portugal)
2021/05/06 Interindividual variability in abcb1 expression in human sertoli cells IJUP'21, Encontro de Investigação Jovem da Universidade do Porto, 14ª Edição
University of Porto, online meeting (Porto, Portugal)
2021/05/06 New marine-derived compounds with promising neuroprotective effects IJUP-21, Encontro de Investigação Jovem da Universidade do Porto, 14ª Edição
University of Porto, online meeting (Porto, Portugal)
2021/05/05 Synthesis and in vitro evaluation of compounds with potential against Alzheimer's Disease IJUP’21, Encontro de Investigação Jovem da Universidade do Porto, 14ª Edição
University of Porto, online meeting (Porto, Portugal)
2021/05/05 Evaluation of modulation of P-glycoprotein expression/activity in HK2 cells IJUP-21, Encontro de Investigação Jovem da Universidade do Porto, 14ª Edição
University of Porto, online meeting (Porto, Portugal)
2021/02/19 Evaluation of modulation of p-glycoprotein expression/activity in hk2 cells. LI Anual Meeting of the Portuguese Pharmacology Society, XXXIX Meeting of Clinical Pharmacology and XX Meeting of Toxicology
Portuguese Pharmacological Society - Faculty of Pharmacy, University of Lisbon (Lisbon - Virtual Meeting, Portugal)
2021/02/19 Interindividual variability in ABCB1 expression in human sertoli cells. LI Anual Meeting of the Portuguese Pharmacology Society, XXXIX Meeting of Clinical Pharmacology and XX Meeting of Toxicology
Portuguese Pharmacological Society - Faculty of Pharmacy, University of Lisbon (Lisbon - Virtual Meeting, Portugal)
2021/02/18 Marine-derived compounds as potential neuroprotective agents LI Anual Meeting of the Portuguese Pharmacology Society, XXXIX Meeting of Clinical Pharmacology and XX Meeting of Toxicology
Portuguese Pharmacological Society - Faculty of Pharmacy, University of Lisbon (Lisbon - Virtual Meeting, Portugal)
2021/02/18 Overcoming tolcapone hepatotoxicity: a nanomedicine-based approach. LI Anual Meeting of the Portuguese Pharmacology Society, XXXIX Meeting of Clinical Pharmacology and XX Meeting of Toxicology
Portuguese Pharmacological Society - Faculty of Pharmacy, University of Lisbon (Lisbon - Virtual Meeting, Portugal)
2020/11/24 Synthesis of potential dual BACE-1/GSK-3ß inhibitors to fight Alzheimer's disease SIFFUP, Simpósio de Investigação da Faculdade de Farmácia da Universidade do Porto, 2.ª edição
Faculty of Pharmacy, University of Porto (Porto, Portugal)
2020/03 Mapping the chromone-3-carboxamide pharmacophore: structure-activity-toxicity and efflux transport studies. 4th WG meeting – MuTaLig COST Action 2020
MuTaLig COST Action (Izmir, Turkey)
2020/02/22 The nanomaterial toolkit for neurological disorders treatment. CIQUP II Workshop Meeting 2020
CIQUP - Research Center in Chemistry (Centro de Investigação em Química da Universidade do Porto) (Porto, Portugal)
2020/02/07 Video lecture capture (vlc) - impact on students' academic results. L Anual Meeting of the Portuguese Pharmacology Society, XXXVIII Meeting of Clinical Pharmacology and XIX Meeting of Toxicology
Portuguese Pharmacology Society (Coimbra, Portugal)
2020/02/07 TOX-OER MOOC: a tool for teaching and learning toxicology worldwide. L Anual Meeting of the Portuguese Pharmacology Society, XXXVIII Meeting of Clinical Pharmacology and XIX Meeting of Toxicology
Portuguese Pharmacology Society (Coimbra, Portugal)
2019/06 Design and development of multi-target agents for neurodegenerative diseases. Paul Ehrlich Euro-PhD Network & MuTaLig COST Action meeting 2019 (MedChem19 Catanzaro)
MedChem19 (Catanzaro, Italy)
2019/06 Looking for the Pharmacophore of Benzopyran MAO-B Inhibitors. Paul Ehrlich Euro-PhD Network & MuTaLig COST Action meeting 2019 (MedChem19 Catanzaro)
MuTaLig COST Action meeting (Catanzaro, Italy)
2019/02/15 Newly synthetized xanthonic derivatives as potential P-glycoprotein modulators: a strategy to fight Alzheimer's disease. XII Meeting of young researchers from the University of Porto (IJUP)
University of Porto (Porto, Portugal)
2019/02/15 Newly synthetized xanthones as potential P-glycoprotein modulators at the intestinal barrier: in vitro and ex vivo studies. XII Meeting of young researchers from the University of Porto (IJUP)
University of Porto (Porto, Portugal)
2019/02/07 In vitro modulation of P-glycoprotein by xanthonic derivates: implications on Alzheimer’s disease. XLIX Annual Meeting of the Portuguese Pharmacology Society, XXXVII Meeting of Clinical Pharmacology and XVIII Meeting of Toxicology
Portuguese Pharmacology Society (Porto, Portugal)
2019/02/07 Xanthones as potential P-glycoprotein modulators: in vitro and ex vivo studies. XLIX Annual Meeting of the Portuguese Pharmacology Society (SPF), XXXVII Meeting of Clinical Pharmacology and XVIII Meeting of Toxicology
Portuguese Pharmacology Society (Porto, Portugal)
2018/02 The effects of 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) on p-glycoprotein activity and expression in the rat intestinal mucosa: an ex vivo and in vivo approach. XLVIII Anual Meeting of the Portuguese Pharmacology Society, XXXVI Meeting of Clinical Pharmacology and XVII Meeting of Toxicology
Portuguese Pharmacology Society (Lisboa, Portugal)
2017/02/10 Small Chiral Molecules as potential P-gp Modulators: Synthesis and Studies of Enantioselectivity. 10º Meeting of young researchers from the University of Porto (IJUP)
University of Porto (Porto, Portugal)
2017/02/10 Screening of newly synthetized xanthonic derivatives as P-glycoprotein modulators - in silico and in vitro studies. 10º Meeting of young researchers from the University of Porto (IJUP)
University of Porto (Porto, Portugal)
2017/02 Identification of newly sinthetized xanthonic derivates as potential P-glycoprotein modulators. XLVII Anual Meeting of the Portuguese Pharmacology Society, XXXV Meeting of Clinical Pharmacology and XVI Meeting of Toxicology
Portuguese Pharmacology Society (Coimbra, Portugal)
2016/02 Effect of hyperthermia on the toxicity of the ‘bath salt’ MDPV in primary cultured rat hepatocytes. XLVI Anual Meeting of the Portuguese Pharmacology Society, XXXIV Meeting of Clinical Pharmacology and XV Meeting of Toxicology
Portuguese Pharmacology Society (Porto, Portugal)
2015/09/16 Induction and activation of P-glycoprotein efflux pump as a therapeutic strategy. 51st Congress of European Societies of Toxicology (EUROTOX 2015)
European Societies of Toxicology (Porto, Portugal)
2014/02 In vitro cardiotoxicity of piperazine designer drugs. XLIV Anual Meeting of the Portuguese Pharmacology Society, XXXII Meeting of Clinical Pharmacology and XIII Meeting of Toxicology
Portuguese Pharmacology Society (Coimbra, Portugal)
2014/02 New thioxanthones and dihydroxylated xanthones as P-glycoprotein inducers/activators. XLIV Anual Meeting of the Portuguese Pharmacology Society, XXXII Meeting of Clinical Pharmacology and XIII Meeting of Toxicology
Portuguese Pharmacology Society (Coimbra, Portugal)
2012/02 Modulation of p-gp expression and activity by novel rifampicin derivative, dibenzrif, in RBE4 cells. XLII Anual Meeting of the Portuguese Pharmacology Society, XXX Meeting of Clinical Pharmacology and XI Meeting of Toxicology
Portuguese Pharmacology Society (Lisboa, Portugal)
2011/02 Cocaine-induced nephrotoxicity: an in vitro study using primary cultured human proximal tubular cells. XLI Annual Meeting of the Portuguese Pharmacology Society, XXIX Meeting of Clinical Pharmacology and X Meeting of Toxicology
Portuguese Pharmacology Society (Coimbra, Portugal)
2011/02 Age-related differences in P-gp expression and activity – a comparative analysis between two p-gp expression and activity determination methods. XLI Anual Meeting of the Portuguese Pharmacology Society, XXIX Meeting of Clinical Pharmacology and X Meeting of Toxicology
Portuguese Pharmacology Society (Coimbra, Portugal)
2011/02 Oxidative damage induced by “ecstasy” and its metabolites in mouse brain synaptosomes. XLI Anual Meeting of the Portuguese Pharmacology Society, XXIX Meeting of Clinical Pharmacology and X Meeting of Toxicology
Portuguese Pharmacology Society (Coimbra, Portugal)
2009/12 Induction of p-glycoprotein expression by doxorubicin protects caco-2 cells against paraquat-induced toxicity. XL Annual Meeting of the Portuguese Pharmacology Society, XXVIII Meeting of Clinical Pharmacology and IX Meeting of Toxicology
Portuguese Pharmacology Society (Porto, Portugal)
2009/09/16 Adrenaline and reactive oxygen species elicit proteome and energetic metabolism modifications in freshly isolated rat cardiomyocytes. 46st Congress of European Society of Toxicology (EUROTOX 2009)
European Society of Toxicology (Dresden, Germany)
2009/09/15 P-glycoprotein induction as a cellular protection tool against xenobiotics toxicity. 46st Congress of European Society of Toxicology (EUROTOX 2009)
European Society of Toxicology (Dresden, Germany)
2008/12 Ethanol plus MDMA: synergistic toxicity towards primary cultured rat hepatocytes. XXXIX Annual Meeting of the Portuguese Pharmacology Society, XXV Meeting of Clinical Pharmacology and VIII Meeting of Toxicology
Portuguese Pharmacology Society (Lisboa, Portugal)
2008/12 Effect of P-glycoprotein inducers on its expression and activity in Caco-2 cells. XXXIX Annual Meeting of the Portuguese Pharmacology Society, XXV Meeting of Clinical Pharmacology and VIII Meeting of Toxicology
Portuguese Pharmacology Society (Lisboa, Portugal)
2008/04 Challenging with adrenaline, under a pro-oxidant environment, decreased proteasome activity, and increased activation of HSF-1 and NF-KB and the expression of HSP70 in isolated cardiomyocytes. International Courses on Toxicology 2008 - “Metabolic Toxicology: From Pathway to Organism
Faculdade de Coimbra (Coimbra, Portugal)
2007/12 Time dependent activation of transcription factors in freshly isolated cardiomyocytes under stimulation by adrenaline and reactive oxygen species. XXXVIII Annual Meeting of the Portuguese Pharmacology Society, XXV Meeting of Clinical Pharmacology and VII Meeting of Toxicology
Portuguese Pharmacology Society (Coimbra, Portugal)
2006/12 Oxidation of adrenaline in cardiomyocytes: formation of adrenochrome, quinoproteins, and GSH- adducts. XXXVII Annual Meeting of the Portuguese Pharmacology Society, XXIV Meeting of Clinical Pharmacology
Portuguese Pharmacology Society (Porto, Portugal)
2006/06 The influence of CYP2D6 polymorphic metabolism on the cytotoxicity of “Ecstasy”. 1º Encontro Nacional de Bromatologia, Hidrologia e Toxicologia
(Sesimbra, Portugal)
2005/12 Development of a procedure to analyse GSH adducts of catecholamines in biological samples. In XXXVI Annual Meeting of the Portuguese Pharmacology Society, XXIII Meeting of Clinical Pharmacology
Portuguese Pharmacology Society (Lisbon, Portugal)

Supervision

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2023/12 - Atual Co-encapsulation of drugs in nanostructured lipid carriers (NLC) as a smart approach to improve treatment of acute migraine via the nose-brain route
Co-supervisor
Universidade do Porto Faculdade de Farmácia, Portugal
2023/12 - Atual Biological characterization of synthetic analogous of sea-derived natural compounds as novel drug candidates for Alzheimer's disease
Supervisor
Universidade do Porto Faculdade de Farmácia, Portugal
2022/01 - Atual Improving Edaravone's mitochondrial targeting using cationic smart carriers: a novel therapeutic approach for Amyotrophic Lateral Sclerosis
Supervisor de Sandra Filipa Carvalho Barreiro
 PhD program in Pharmaceutical Sciences (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/01 - Atual Modulation of P-glycoprotein expression/activity at kidney level: a new therapeutic strategy to reduce cisplatin-induced nephrotoxicity
Supervisor de Jéssica Matos
 PhD program in Pharmaceutical Sciences (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/09 - Atual Screening of new multitarget drugs for the treatment of Amyotrophic Lateral Sclerosis by targeting iron dysregulation and oxidative stress.
Supervisor de Rita Marques Oliveira
 MSc in analytical, clinical and forensics Toxicology (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/03/01 - Atual Dual-acting drugs targeting Ferroptosis and COMT: a new potential therapeutic strategy to fight Parkinson's Disease
Co-supervisor de Vera Lúcia Santos Silva
 PhD in Pharmaceutical Sciences (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/01/01 - Atual ROS-sensitive nanoparticles as carriers for Edaravone delivery: an innovative strategy in Amyotrophy Lateral Sclerosis treatment.
Co-supervisor de Brandon Lage Aguiar
 PhD in Pharmaceutical Sciences (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/12/01 - Atual Phenethylamine derivatives: new insights on their pharmacological and toxicological profile.
Supervisor de Eva Alexandra Gil Martins
 PhD in Pharmaceutical Sciences (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/10 - Atual Descoberta de novas entidades Químicas como Moduladores da Glicoproteína-P
Supervisor de Sandra António Monjane
 Mestrado em Ciências e Técnicas Laboratoriais Forenses (Master)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2023 - 2024/12/17 Efeitos das catinonas sintéticas metilona e pentedrona no desenvolvimento, função reprodutora e longevidade do modelo animal C. elegans
Co-supervisor
 MSc in Forensic Sciences (Master)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2023 - 2024/12/13 Neuroprotective potential of natural antioxidants targeting oxidative stress in Alzheimer's disease
Supervisor
 MSc in analytical, clinical and forensics Toxicology (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2023 - 2024/12/09 Unravelling the neurotoxicity of synthetic cathinones in a neuritogenesis model
Supervisor
 MSc in analytical, clinical and forensics Toxicology (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2023 - 2024/10/08 A Deep Dive into the Untapped Potential of Marine Compounds in Counteracting Neurodegeneration
Supervisor
 PhD Seminar of the 3rd Cycle of Studies in Pharmaceutical Sciences on the Specialty of Toxicology (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2023 - 2024/07/24 Efeitos da catinona sintética 4-Metiletilcatinona no desenvolvimento, comportamento reprodutor e longevidade do modelo animal C. elegans
Co-supervisor
 Curricular Unit of Metodology and Project in Forensic Investigation, 1st Cycle of Studies in Forensic Sciences (Other)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2023 - 2024/07/17 Screening of Novel Synthetic Derivatives for Countering Neurodegeneration
Supervisor
 Curricular Unit of Metodology and Project in Forensic Investigation, Degree in Forensic Laboratorial Sciences (Other)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2023/01 - 2024/06/27 Synthetic cathinones: from psychostimulation to the onset of psychiatric disorders
Supervisor de Catarina Teixeira da Fonseca
Seminar of the MSc in analytical, clinical and forensics Toxicology (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2023/01 - 2024/06/27 Unlocking Alzheimer’s Disease: Bridging pathophysiology to the therapeutic potential of Natural Anthocyanins.
Supervisor de Érica Filipa Ferreira Fonseca
Seminar of the MSc in analytical, clinical and forensics Toxicology (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2022 - 2024/03/13 Targeting Mitochondria and Oxidative Stress in Amyotrophic Lateral Sclerosis: Therapeutic Approaches and Challenges
Supervisor
 PhD Seminar of the 3rd Cycle of Studies in Pharmaceutical Sciences on the Specialty of Toxicology (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2023 - 2024/03/08 Using lipid nanoparticles as a smart approach to improve the treatment of acute migraine via the nose-brain route
Co-supervisor
 PhD Seminar of the 3rd Cycle of Studies in Pharmaceutical Sciences on the Specialty of Pharmaceutical technology (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/09 - 2022/12/16 In vitro study of Innovative Antiparkinsonian agents: evaluation of their toxicological profile and neuroprotective potential.
Supervisor de Inês Silva Ferreira da Costa
 MSc in analytical, clinical and forensics Toxicology (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/09 - 2022/12/16 Alzheimer's disease: unraveling the biological activity of novel synthetic compounds targeting tau hyperphosphorylation and the amyloid-beta pathway.
Supervisor de Ana Rita Pinto Monteiro
 MSc in analytical, clinical and forensics Toxicology (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/09 - 2022/12/14 Development of lipid-based nanosystems (SLN and NLC) for nose-to-brain delivery: a potential strategy for the treatment of neurodegenerative diseases.
Supervisor de José Miguel Rodrigues Pereira
 MSc in analytical, clinical and forensics Toxicology, Faculty of Pharmacy, University of Porto (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/09 - 2022/09/14 Dual-Acting 3-Hydroxypyridin-4(1H)-One Derivatives as an Innovative Strategy in the Treatment of Parkinson's Disease
Supervisor de Tiago Alexandre Ferreira Gonçalves
Degree in Biochemistry - Curricular Unit of Project/Internship (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2021/09 - 2022/09/14 Exploring the Neurotoxic Effects of New Psychoactive Phenethylamine Derivatives
Supervisor de Ana Beatriz Borer de Oliveira Rodrigues
Degree in Biochemistry - Curricular Unit of Project/Internship (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2021/12 - 2022/07/26 Study models of drug-drug interactions involving p-glycoprotein: the potential benefit of P-glycoprotein modulation at kidney level
Supervisor de Jéssica Patrícia Veiga Matos
 PhD Seminar of the 3rd Cycle of Studies in Pharmaceutical Sciences on the Specialty of Toxicology (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/10 - 2022/07/26 Lipid-based nanosystems for brain delivery of natural compounds: a potential strategy for the treatment of neurodegenerative diseases.
Supervisor de José Miguel Rodrigues Pereira
 Seminário do Mestrado em Toxicologia Analítica, Clínica e Forense (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/09 - 2022/07/25 The wonderful unknown world of Parkinson's disease: elucidation of the pathophysiological mechanisms unraveling new potential disease-modifying approaches and drug repurposing.
Co-supervisor de Vera Lúcia Santos Silva
 Seminar of the 3rd Cycle of Studies in Pharmaceutical Sciences on the Specialty of Toxicology. (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/10 - 2022/07/22 In vitro and in vivo models as outstanding tools for modeling amyotrophic lateral sclerosis.
Supervisor de Rita Marques Oliveira
 Seminário do Mestrado em Toxicologia Analítica, Clínica e Forense (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/09 - 2022/07/20 ROS–Sensitive Nanoparticles as Drug Delivery Systems
Co-supervisor
 PhD Seminar of the 3rd Cycle of Studies in Pharmaceutical Sciences on the Specialty of Toxicology (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/09 - 2022/07/12 Desenvolvimento e avaliação da biocompatibilidade de uma formulação intranasal de nanopartículas lipídicas contendo um antiepilético
Co-supervisor de Inês Lascasas
Mestrado Integrado em Ciências Farmacêuticas - unidade curricular Projeto I (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/10 - 2021/11/08 Co-culture models: key players in in vitro neuroscience studies.
Supervisor de Ana Rita Pinto Monteiro
 Seminário do Mestrado em Toxicologia Analítica, Clínica e Forense (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/10 - 2021/10/06 Synthesis and neuroprotection studies of new xanthenes and fluorenes.
Co-supervisor de Márcia Sofia Silva Martins
 MSc in Pharmaceutical Chemistry (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/09 - 2021/09/10 New Psychoactive Derivatives of Phenethylamine: Elucidation of their Toxicology Profiles.
Supervisor de Catarina Teixeira da Fonseca
Degree in Biochemistry - Curricular Unit of Project/Internship (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2020/10 - 2021/07/26 Targeting Ferroptosis as a new approach in the treatment of neurodegenerative diseases
Supervisor de Inês Silva Ferreira da Costa
 Seminário do Mestrado em Toxicologia Analítica, Clínica e Forense (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2020 - 2021/07/22 The Toxicology Behind 2C and NBOMe Psychedelic Phenethylamines
Supervisor de Eva Alexandra Gil Martins
PhD Seminar of the 3rd Cycle of Studies in Pharmaceutical Sciences on the Specialty of Toxicology (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/09 - 2021/07/08 Avaliação dos potenciais efeitos neuroprotetores de novos derivados de xantenos.
Co-supervisor de Daniela Patrícia Gomes Arteiro
Degree in Biomedical Sciences - Curricular Unit of Research Internship in Biomedical Sciences (Degree)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2019/07/01 - 2020/12/11 Marine-derived compounds as potential neuroprotective agents.
Supervisor de Sandra Filipa Carvalho Barreiro
 MSc in analytical, clinical and forensics Toxicology (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/07/01 - 2020/10/07 ADME/TOX studies for new pharmacological agents.
Supervisor de Sandra Filipa Carvalho Barreiro
 Seminário do Mestrado em Toxicologia Analítica, Clínica e Forense (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/09 - 2020/09/16 Avaliação do potencial neuroprotetor de novos compostos marinhos na doença Parkinson.
Supervisor de Maria João do Carmo Martins
 Unidade Curricular de Metodologia e Projeto em Investigação Forense, Licenciatura em Ciências Laboratoriais Forenses (Other)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2019/09 - 2020/07/28 Brain Targeted PEGylated nanoparticles containing Riluzole: an innovative strategy to fight amyotrophic lateral sclerosis.
Supervisor de Rita Marques Oliveira
 Unidade Curricular de Metodologia e Projeto em Investigação Forense, Licenciatura em Ciências Laboratoriais Forenses (Other)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2019/10 - 2020/07/03 Marine Natural Products, Multitarget Therapy and Repurposed Agents in Alzheimer's disease.
Co-supervisor de Márcia Sofia Silva Martins
 Seminar of the MSc in Pharmaceutical Chemistry (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/09 - 2020/07 Avaliação da eficácia in vitro e in vivo de nanossistemas lipídicos para administração intranasal de fármacos usados no tratamento da epilepsia
Co-supervisor de Cláudia Teixeira
Mestrado Integrado em Ciências Farmacêuticas - unidade curricular Projeto I (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/07 - 2019/10/30 Screening of new synthetic derivatives as potential P-glycoprotein modulators.
Supervisor de Bárbara Antónia da Silva Cruz
 Mestrado em Ciências Forenses (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2018/09 - 2019/09/19 Discovery of new chemical entities as potential P-glycoprotein modulators.
Supervisor de Sandra António Monjane
 Unidade Curricular de Metodologia e Projeto em Investigação Forense, Licenciatura em Ciências Laboratoriais Forenses (Other)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2018/07 - 2019/05/03 P-glycoprotein: Clinical and Forensic Relevance.
Supervisor de Bárbara Antónia da Silva Cruz
 Seminário do Mestrado em Ciências Forenses (Specialization course)
Universidade do Porto Faculdade de Medicina, Portugal
2017/07 - 2018/11/21 Newly synthetized xanthones as potential P-glycoprotein and BCRP modulators at the intestinal barrier: in vitro and ex vivo studies.
Co-supervisor de Vera Lúcia Santos Silva
 Mestrado em Toxicologia Analítica, Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2017/07 - 2018/11/19 Screening of newly synthetized xanthonic derivatives as potential P-glycoprotein inducers/activators: an innovative strategy to fight Alzheimer's disease.
Supervisor de Eva Alexandra Gil Martins
 Mestrado em Toxicologia Analítica, Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/07 - 2018/07/26 Role of ABC transporters in neurodegenerative diseases.
Supervisor de Eva Alexandra Gil Martins
 Seminário do Mestrado em Toxicologia Analítica Clínica e Forense (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2017/09 - 2018/07/16 Evaluation of potencial activation/inducing activities of newly synthetized compounds.
Supervisor de Carolina Beatriz Cunha Pisoeiro
 Unidade Curricular de Metodologia e Projeto em Investigação Forense, Licenciatura em Ciências Laboratoriais Forenses (Other)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2016/07 - 2017/10/31 Development and optimization of an UPLC-MS/MS method for the simultaneous detection and quantification of 14 antihypertensive drugs in human urine samples.
Supervisor de Maria Bernardes André
 Mestrado em Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/07 - 2017/07/11 ABC Transporters and potential antidotal pathways.
Co-supervisor de Vera Lúcia Santos Silva
 Seminário do Mestrado em Toxicologia Analítica Clínica e Forense (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2017/03 - 2017/07 Screening of new xanthonic derivatives as potential P-gp modulators
Supervisor de Marta Rogowska
 Projeto II do Mestrado em Ciências Farmacêuticas - FFUP (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2015/09 - 2016/11/22 Small chiral molecules as modulators of P-gp: Synthesis and Enantioselectivity Studies
Co-supervisor de Ana Catarina Barros Lopes
 Mestrado em Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2015/09 - 2016/11/16 Identificação de derivados xantónicos como potenciais indutores/ativadores da glicoproteína-P
Co-supervisor de Ana Cecília Coelho Rodrigues
 Mestrado em Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/03 - 2016/07 Evaluation of the cytotoxicity of newly synthetized thioxantones in an in vitro model of the human intestinal epithelium
Supervisor de Martyna Piskorska
 Projeto II do Mestrado em Ciências Farmacêuticas (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/02 - 2016/06/28 Study of the cytotoxicity and potential P-gp modulation of newly synthetized xanthones with therapeutic potential.
Supervisor de Tânia Rito
 Projeto I do Mestrado em Ciências Farmacêuticas (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2015/06 - 2016/06/04 Study of the cytotoxicity and transport of new P-glycoprotein substrates with potential therapeutic application
Supervisor de Eva Alexandra Gil Martins
 Biologia (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2014/09 - 2015/11/19 Estudo da Permeabilidade da TX5 em Caco-2 e RBE4 - um potencial indutor/ativador da Glicoproteína-P
Co-supervisor de André Quelhas
Mestrado em Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2014/07 - 2015/07 The importance of Chirality in Clinical Toxicology
Co-supervisor de Ana Catarina Barros Lopes
 Seminário do Mestrado em Toxicologia Analítica Clínica e Forense (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal
2013/09 - 2014/11 Estudo da Glicoproteína-P em Linfócitos T Humanos e em Plasma de Ratos Charles Rivers usando a TX5 como Potencial Indutor da sua Expressão e Actividade
Co-supervisor de Ana Filipa Pereira Ferreira
 Mestrado em Toxicologia Analítica, Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2013/02 - 2013/09/13 Evaluation of the P-gp expression and activity in Caco-2 cells in presence of thioxanthonic compounds. Role in paraquat cytotoxicity
Supervisor de Ana Patrícia Gomes Gonçalves Moreira
 Projeto I do Mestrado em Ciências Farmacêuticas (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2012/09 - 2013/09/12 Screening and application of P-glycoprotein (P-gp) inducers in the toxicity of xenobiotics.
Supervisor de Mariana Azevedo Soares
 Licenciatura em Ciências Forenses e Criminais (Degree)
Cooperativa de Ensino Superior Politécnico e Universitário, Portugal

Event organisation

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2019/02/06 - 2019/02/08 XLIX Meeting of the Portuguese Pharmacology Society, XXXVII Meeting of Clinical Pharmacology, XVIII Meeting of Toxicology (2019/02/06 - 2019/02/08)
Meeting (Other)
 Universidade do Porto Faculdade de Farmácia, Portugal

Event participation

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2022/02/09 - 2022/02/11 SPF 2022 - Reunião Anual da Sociedade Portuguesa de Farmacologia O Instituto de Ciências Biomédicas de Abel Salazar da Universidade do Porto vai acolher, de 9 a 11 de fevereiro de 2022, a 52ª Reunião da Sociedade Portuguesa de Farmacologia, 40ª Reunião de Farmacologia Clínica e 21ª Reunião de Toxicologia. A Sociedade Portuguesa de Farmacologia (SPF) desempenha um papel singular e fundamental no desenvolvimento científico da Farmacologia Experimental, Farmacologia Clínica e Toxicologia em Portugal. Sendo a principal representante destas áreas a ní
Conference
 SPF 2022 - Reunião Anual da Sociedade Portuguesa de Farmacologia
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Jury of academic degree

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2022/12/16 In vitro study of Innovative Antiparkinsonian agents: evaluation of their toxicological profile and neuroprotective potential
Supervisor
 Inês Silva Ferreira da Costa (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/12/16 Alzheimer's disease: unraveling the biological activity of novel synthetic compounds targeting tau hyperphosphorylation and the amyloid-beta pathway.
Supervisor
 Ana Rita Pinto Monteiro (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/12/14 Development of lipid-based nanosystems (SLN and NLC) for nose-to-brain delivery: a potential strategy for the treatment of neurodegenerative diseases
Supervisor
 José Miguel Rodrigues Pereira (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/12/11 Marine-derived compounds as potential neuroprotective agents.
Supervisor
 Sandra Filipa Carvalho Barreiro (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/01/12 Development of new chemical entities based on natural scaffolds with therapeutic potential towards age-related disorders
Thesis Member
 Daniel Freitas Chavarria (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/11/17 In vivo hepatotoxicity of the new drugs of abuse 3,4-dimethylmethcathinone (3,4-DMMC) and methylone.
(Thesis) Main arguer
 Catarina Tavares Teixeira (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/10/30 Screening of new synthetic derivatives as potential P- glycoprotein modulators
Supervisor
 Bárbara Antónia da Silva Cruz (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2018/11/19 Screening of newly synthetized xanthonic derivatives as potential P-glycoprotein inducers/activators: an innovative strategy to fight Alzheimer's disease.
Supervisor
 Eva Alexandra Gil Martins (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/07/11 Development of PEGylated platforms to overcome blood-brain barrier constraints in neurodegenerative therapy
Thesis Member
 Carlos Eduardo Vinhas Fernandes (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2017/10/31 Development and optimization of an UPLC-MS/MS method for the simultaneous detection and quantification of 14 antihypertensive drugs in human urine samples
Supervisor
 Maria Bernardes André (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/12/06 Comparação da citotoxicidade de fármacos anticancerígenos e da sua mistura em células H9c2 diferenciadas
(Thesis) Main arguer
 Maria do Rosário Pereira Oliveira (Master)
Universidade de Aveiro Departamento de Biologia, Portugal
2016/11/16 Identificação de derivados xantónicos como potenciais indutores/ativadores da glicoproteína P
Supervisor
 Ana Cecília Coelho Rodrigues (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2015/12/10 Implementation and validation of an analytical method for the quantification of opioids in nails - Simultaneous quantitation of morphine, 6- monoacetylmorphine, methadone, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and 2-ethyl-5-methyl-3,3-diphenylpyrroline by gas chromatography coupled to mass spectrometry in nail fragments from individuals undergoing methadone substitution therapy
(Thesis) Main arguer
 Teresa Patrícia Moreira Magalhães (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2015/11/30 Mechanisms of Regulation of P-glycoprotein and Breast Cancer Resistance Protein at the Blood-Brain Barrier: Focus on the Role of Morphine, and P-glycoprotein Activation. Thesis completed in 30th November 2015. The jury attributed the title of Docteur of the University Paris Descartes and University of Porto, with the mention "Très Honorable", by unanimity. Faculty of Pharmacy, Universités Paris Descartes - Paris Diderot.
Thesis Member
 Catarina Alexandra da Silva Chaves (PhD)
Faculty of Pharmacy, Universités Paris Descartes – Paris Diderot., France

Association member

Nome da associação Tipo de participação
2016 - Atual Portuguese Pharmacology Society Member

Committee member

Descrição da atividade
Tipo de participação 		Instituição / Organização
2017/10/23 - 2017/10/27 Intensive Learners Meeting on Pharmaco/Toxicokinetics within the TOX-OER (Learning Toxicology through Open Educational Resources) project, which aims to design and develop an international Massive Open Online Course (MOOC) on Toxicology. This course toke place at the Faculty of Pharmacy, University of Porto, Porto (Portugal), with a total duration of 30 hours.
Member
 Universidade do Porto Faculdade de Farmácia, Portugal

Consulting

Descrição da atividade Instituição / Organização
2021/01 - Atual Responsible, at the laboratory of toxicology of FFUP , for measuring copper and iron by atomic absorption spectrometry in human liver biopsies for the diagnosis of Wilson's disease and Hemachromatosis, respectively. The result of the analyzes carried out is an indispensable tool for a correct diagnosis, being a very important contribution for the medical community and society in general. Universidade do Porto Faculdade de Farmácia, Portugal
2021/01 - 2021/12 Responsible, at the laboratory of toxicology of FFUP , for the determination of metals by atomic absorption spectrometry in raw materials used in the production of medicines. The result of the analyzes carried out has a high impact on the production cycle of the Bial Pharmaceutical Industry.

Evaluation committee

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2025/02/07 - 2025/02/07 Event moderator in the Parallel Oral Communication Session 17 of the 55th Meeting of the Portuguese Society of Pharmacology, 43rd Meeting of Clinical Pharmacology and 24th Meeting of Toxicology. Evaluation committee participation in 2025. 7th February 2025, Faculty of Medicine of University of Porto, Porto, Portugal.
Evaluator
 Universidade do Porto Faculdade de Medicina, Portugal
2021/07/18 - 2021/07/18 Event moderator in the Toxicology I Section of the LI Annual Meeting of the Portuguese Society of Pharmacology, XXXIX Meeting of Clinical Pharmacology and XX Meeting of Toxicology.
Evaluator
 Universidade de Lisboa Faculdade de Farmácia, Portugal

Other jury / evaluation

Descrição da atividade Instituição / Organização
2022/09/14 - 2022/09/14 Juri Participation -Supervisor. Student - Tiago Alexandre Ferreira Gonçalves, with the work "Dual-Acting 3-Hydroxypyridin-4(1H)-One Derivatives as an Innovative Strategy in the Treatment of Parkinson's Disease". Curricular Unit of Project/Internship, Degree in Biochemistry, Faculty of Sciences and Abel Salazar Institute of Biomedical Sciences. Academic year 2021/2022. Supervisor. Qualifying examination in 14th September 2022 with a final grade of 20 values (scale of 1-20). Faculty of Sciences of University of Porto. Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/09/14 - 2022/09/14 Juri Participation - Supervisor. Student - Ana Beatriz Borer de Oliveira Rodrigues, with the work "Exploring the Neurotoxic Effects of New Psychoactive Phenethylamine Derivatives". Curricular Unit of Project/Internship, Degree in Biochemistry, Faculty of Sciences and Abel Salazar Institute of Biomedical Sciences. Academic year 2021/2022. Qualifying examination in 14th September 2022 with a final grade of 19 values (scale of 1-20). Faculty of Sciences of University of Porto. Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/07/27 - 2022/07/27 Juri Participation - Arguer. Master Student - Ana Rita Tavares Henriques. Seminar of the Master in Analytical, Clinical and Forensic Toxicology entitled "Opioids and accelerated aging". Seminar completed in 27th July 2022 (online), with a final grade of 19 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2022/07/26 - 2022/07/26 Juri Participation - Supervisor. Master Student - José Miguel Rodrigues Pereira. Seminar of the Master in Analytical, Clinical and Forensic Toxicology entitled "Lipid-based nanosystems for brain delivery of natural compounds: a potential strategy for the treatment of neurodegenerative diseases". Seminar completed in 26th July 2022 (online), with a final grade of 18 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2022/07/22 - 2022/07/22 Juri Participation - Supervisor. Master Student - Rita Marques Oliveira. Seminar of the Master in Analytical, Clinical and Forensic Toxicology entitled "In vitro and in vivo models as outstanding tools for modeling amyotrophic lateral sclerosis". Seminar completed in 22th July 2022 (online), with a final grade of 19 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2022/07/22 - 2022/07/22 Juri Participation -supervisor. PhD Student - Jéssica Patrícia Veiga Matos. PhD Seminar of the 3rd Cycle of Studies in Pharmaceutical Sciences on the Specialty of Toxicology entitled "Study models of drug-drug interactions involving p-glycoprotein: the potential benefit of P-glycoprotein modulation at kidney level". Seminar completed in 26th July 2022 with a final grade of 19 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2022/07/18 - 2022/07/18 Juri Participation - Arguer. PhD Student - Armanda do Carmo Ferreira Abreu de Sousa Correia. PhD Seminar of the 3rd Cycle of Studies in Pharmaceutical Sciences entitled "Key factors of lipid nanoparticles formulations to optimize nose-to-brain drug delivery". Seminar completed in 18th July 2022 (online), with a final grade of 19 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2021/11/08 - 2021/11/08 Juri Participation - Supervisor. Master Student - Ana Rita Pinto Monteiro. Seminary of the Master in Analytical, Clinical and Forensic Toxicology entitled "Co-culture models: key players in in vitro neuroscience studies". Qualifying examination (Equivalence in Scientific MSc in Analytical, Clinical and Forensic Toxicology). Seminar completed in 8th November 2021 with a final grade of 20 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2021/09/10 - 2021/09/10 Juri Participation - supervisor. Student - Catarina Teixeira da Fonseca. Seminary of the Curricular Unit Project/internship of the Graduation in Biochemistry ICBAS/FCUP, entitled "New Psychoactive Derivatives of Phenethylamine: Elucidation of their Toxicology Profiles ". Qualifying examination. Dissertation completed in 10th September 2021. Instituto de Ciências Biomédicas Abel Salazar (ICBAS), University of Porto. Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/07/29 - 2021/07/29 Juri Participation - Supervisor. Master Student - Inês Silva Ferreira da Costa. Seminary of the Master in Analytical, Clinical and Forensic Toxicology entitled "Targeting Ferroptosis as a new approach in the treatment of neurodegenerative diseases". Qualifying examination (Equivalence in Scientific MSc in Analytical, Clinical and Forensic Toxicology). Seminar completed in 29th July 2021 (online) with a final grade of 20 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2021/07/26 - 2021/07/26 Juri Participation - arguer. Student - Ana Olívia Pires Fernandes. Seminary of the Curricular Unit Project/internship of the Graduation in Biochemistry ICBAS/FCUP, entitled " The Long-term Mechanisms of Chemobrain: Neurotoxicity of Doxorubicin in CD-1 Mice". Qualifying examination. Dissertation completed in 26th July 2021 (online). Instituto de Ciências Biomédicas Abel Salazar (ICBAS), University of Porto. Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/07/22 - 2021/07/22 Juri Participation - Supervisor. PhD Student - Eva Alexandra Gil Martins. PhD Seminar of the 3rd Cycle of Studies in Pharmaceutical Sciences on the Specialty of Toxicology entitled ¿The Toxicology Behind 2C and NBOMe Psychedelic Phenethylamines¿. Qualifying examination. Seminar completed in 22th July 2021 (online) with a final grade of 19 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2020/10/07 - 2020/10/07 Juri Participation - Supervisor. Master Student - Sandra Filipa Carvalho Barreiro. Seminary of the Master in Analytical, Clinical and Forensic Toxicology, entitled "ADME/TOX studies for new pharmacological agents". Qualifying examination (Equivalence in Scientific MSc in Analytical, Clinical and Forensic Toxicology). Seminar completed in 7th October 2020 with a final grade of 19 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2020/09/16 - 2020/09/16 Juri Participation - Supervisor. Student - Maria João do Carmo Martins. Curricular Unit of Metodology and Project in Forensic Investigation, Degree in Forensic Laboratorial Sciences, Instituto Superior de Ciências da Saúde Norte, with the work entitled "Avaliação do potencial neuroprotetor de novos compostos marinhos na doença Parkinson¿. Qualifying examination in 16th September 2020 with a final grade of 17 values (scale of 1-20). Instituto Superior de Ciências da Saúde Norte. Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2020/07/28 - 2020/07/28 Juri Participation - Supervisor. Student - Rita Marques Oliveira. Curricular Unit of Metodology and Project in Forensic Investigation, Degree in Forensic Laboratorial Sciences, Instituto Superior de Ciências da Saúde Norte., with the work entitled " Brain Targeted PEGylated nanoparticles containing Riluzole: an innovative strategy to fight amyotrophic lateral sclerosis¿. Qualifying examination in 28th July 2020 with a final grade of 19 values (scale of 1-20). Instituto Superior de Ciências da Saúde Norte. Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2019/07/22 - 2019/07/22 Juri Participation - Arguer. Master Student - Jéssica Patrícia Veiga Matos. Seminary of the Master in Analytical, Clinical and Forensic Toxicology entitled "Toxicokinetic role of membrane transporters at kidney level". Qualifying examination (Equivalence in Scientific MSc in Analytical, Clinical and Forensic Toxicology). Dissertation completed in 22th July 2019 with a final grade of 19 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2019/07/08 - 2019/07/08 Juri Participation - arguer. Student - Ana Catarina Oliveira Trigo. Curricular Unit - Projecto/Estágio (BIOQ3001) of the degree in Biochemistry ICBAS/FCUP, University of Porto, with the work entitled "Insights on Nitric Oxide in Carcinogenesis". Qualifying examination in 8th July 2019. ICBAS, University of Porto. Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
2018/07/26 - 2018/07/26 Juri Participation - supervisor. Master Student - Eva Alexandra Gil Martins. Seminary of the Master in Analytical, Clinical and Forensic Toxicology entitled "Role of ABC transporters in neurodegenerative diseases". Qualifying examination (Equivalence in Scientific MSc in Analytical, Clinical and Forensic Toxicology). Dissertation completed in 26th July 2018 with a final grade of 20 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2018/07/17 - 2018/07/17 Juri Participation - arguer. Student - Rui Filipe Almeida Da Silva. Project I of the MSc in Pharmaceutical Sciences, Faculty of Pharmacy, University of Porto, with the work entitled "Unravelling the mechanisms behind microglia control of purinergic-mediated astroglial proliferation". Qualifying examination in 17 July 2018 with a final grade of 19 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2018/07/17 - 2018/07/17 Juri Participation - arguer. Student - Soraia Daniela Monteiro Vaz. Project I of the MSc in Pharmaceutical Sciences, Faculty of Pharmacy, University of Porto, with the work entitled "Avaliação da compatibilidade e do potencial de hidratação cutânea de formulações à base de nanossistemas lipídicos contend vitamima E. Qualifying examination in 17th July 2018 with a final grade of 19 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2017/07/11 - 2017/07/11 Juri Participation - Arguer. Master Student - João André da Costa Alexandre. Seminary of the Master in Analytical, Clinical and Forensic Toxicology entitled "Synthetic Cannabinoids and their role in neuronal regulation". Qualifying examination (Equivalence in Scientific MSc in Analytical, Clinical and Forensic Toxicology). Dissertation completed in 11th July 2017 with a final grade of 19 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2017/07/07 - 2017/07/07 Juri Participation - Arguer. Student - Cristina Maria Ferreira Almeida. Seminary of the Curricular Unit Project/internship of the Graduation in Biochemistry ICBAS/FCUP, entitled "The effects of Cannabinoids in Exesmestane/resistant breast cancer cells". Qualifying examination. Dissertation completed in 7th July 2017 with a final grade of 19 values (scale of 1-20). Instituto de Ciências Biomédicas Abel Salazar (ICBAS), University of Porto. Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/06/30 - 2017/06/30 Juri Participation - Arguer. Master Student - Nuno Filipe Santos Magalhães. Seminary of the Master in Analytical, Clinical and Forensic Toxicology entitled "Human and Experimental Toxicology of Diquat". Qualifying examination (Equivalence in Scientific MSc in Analytical, Clinical and Forensic Toxicology). Dissertation completed in 30th June 2017 with a final grade of 18 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2016/03/03 - 2016/03/03 Juri Participation - arguer. Student - Joana Raquel Machado Pedroso. Project I of the MSc in Pharmaceutical Sciences, Faculty of Pharmacy, University of Porto, with the work entitled "Estudo in vitro da captação intracelular e da permeabilidade intestinal de nanopartículas metálicas com potencial interesse para aplicações biomédicas e na indústria alimentar". Qualifying examination in 03 March 2016 with a final grade of 19 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2015/07/28 - 2015/07/28 Juri Participation - Arguer. Master Student - Joana Daniela da Silva Costa. Seminary of the Master in Quality Control entitled "A brief review of in vivo studies for ADME assessment of nanoparticles after oral administration". Qualifying examination (Equivalence in Scientific MSc in Quality Control). Dissertation completed in 28th July 2015 with a final grade of 19 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
2015/07/27 - 2015/07/27 Juri Participation - Arguer. Pre-graduate student - Rui Filipe Libânio Osório Marta. Dissertation for obtaining the Degree of licentiate in Forensic Laboratorial Sciences. Dissertation entitled "Análise diferencial por sexo e idade em cabelo: preparação da amostra para obtenção de um biomarcador (Differential Hair analysis by gender and age: sample preparation to obtain a biomarker)". Dissertation completed in 27th July 2015 with a final grade of 19 values (scale of 1-20). Instituto Superior de Ciências da Saúde Norte. July 27, 2015. Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2014/06/18 - 2014/06/18 Juri Part - Arguer. Master Student - Luís Filipe Braga da Silva Ferreira. Seminary of the Master's in Analytical, Clinical and Forensic Toxicology entitled "Transportadores transmembranares e a sua relevância na Barreira Hematoencefálica (Transmembrane transporters and their relevance in the Blood-Brain Barrier)". Qualifying examination (Equivalence in Scientific MSc in Analytical, Clinical and Forensic Toxicology). Dissertation completed in 18th June 2014 with a final grade of 18 values (scale of 1-20). Faculty of Pharmacy, University of Porto. Universidade do Porto Faculdade de Farmácia, Portugal
Distinções

Award

2023 BEST POSTER COMUNICATION
Instituto Universitário de Ciências da Saúde Unidade de Investigação em Toxicologia, Portugal
2023 BEST POSTER COMUNICATION
Universidade do Porto, Portugal
2023 BEST ORAL COMUNICATION
Universidade do Porto, Portugal
2022 BEST POSTER PRESENTATION
Universidade do Porto, Portugal
2020 BEST POSTER COMUNICATION
4th WG meeting – MuTaLig COST Action, Turkey
2020 BEST ORAL COMUNICATION
4th WG meeting – MuTaLig COST Action, Turkey
2017 BEST POSTER COMUNICATION
Associação Portuguesa de Ciências Forenses, Portugal
2007 MOST VOTED POSTER
Rede Nacional de Espectrometria de Massa, Portugal

Other distinction

2015 FCT Postdoctoral fellowship
Fundação para a Ciência e a Tecnologia, Portugal
2007 FCT Doctoral Fellowship
Fundação para a Ciência e a Tecnologia, Portugal