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Giacomo Domenici (Rome, Italy, 1985), holds an MSc in Pharmaceutical Biotechnology from the University of Rome "La Sapienza" and a Ph.D. in Molecular Biology and Biomedicine (September 2017) from the University of Basque Country (Spain). His Ph.D. Thesis research work was performed in the research center CICbioGUNE (Derio, Bilbao, Spain). During this time, he was focused on cancer cell biology, with a special focus on breast cancer. His research shed light on the role of SOX transcription factors involved with breast cancer tumorigenesis, cancer stem cells and endocrine resistance, and the results of his research were published in international journals and scientific conferences. In 2018, he joined as PostDoc researcher the Laboratory of Advanced Cell Models led by Dr Catarina Brito (Animal Cell Technology Unit) at the Instituto de Biologia Experimental e Tecnológica (iBET) and, since 2019, as Associate Scientist. Currently, his main research areas are focused on the development and application of advanced 3D in vitro cell models for cancer research and neuroscience. A special focus has been given to breast cancer and more recently on rare tumors such as Ewing's Sarcoma and pediatric gliomas. He has been also involved in industry project management as well as MSc and PhD students' supervision. Other key areas of interest include the innate immune response, the tumor microenvironment, oncoimmunology and the development of novel targeted therapies against cancer.
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Identification

Personal identification

Full name
Giacomo Domenici
Date of birth
1985/12/03
Gender
Male

Citation names

  • Domenici, Giacomo

Author identifiers

Ciência ID
3515-F242-8597
ORCID iD
0000-0002-3947-5930

Email addresses

  • giacomo.domenici@ibet.pt (Professional)

Telephones

Mobile phone
  • 916120146 (Personal)

Addresses

  • Av. da República, 2780-157 Oeiras, Portugal, 2780-157, Oeiras, Oeiras, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism

Languages

Language Speaking Reading Writing Listening Peer-review
Italian (Mother tongue)
English Advanced (C1) Proficiency (C2) Proficiency (C2) Advanced (C1) Proficiency (C2)
Spanish; Castilian Proficiency (C2) Proficiency (C2) Advanced (C1) Proficiency (C2) Proficiency (C2)
Portuguese Advanced (C1) Proficiency (C2) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2017/09/21
Concluded
 Molecular Biology and Biomedicine (Doctor of Philosophy)
Universidad del País Vasco - Campus Bizkaia, Spain

Centro de Investigación Cooperativa en Biociencias, Spain
"ROLE OF SOX9 TRANSCRIPTION FACTOR IN HUMAN BREAST EPITHELIAL CELLS, BREAST CANCER STEM CELLS AND TAMOXIFEN RESISTANCE" (THESIS/DISSERTATION)
 Full Marks with honours
2008/05 - 2010/01/20
Concluded
 Pharmaceutical Biotechnology (Laurea Specialistica)
Università degli Studi di Roma La Sapienza, Italy
 Full Marks with Honours
2004/05/01 - 2007/07/20
Concluded
 Biotechnology (Bachelor)
Università degli Studi di Roma Tor Vergata Dipartimento di Biologia, Italy
 Full Marks with Honours
Affiliation

Science

Category
Host institution 		Employer
2019/01/01 - Current Researcher (Research) Instituto de Biologia Experimental e Tecnológica, Portugal
Instituto de Biologia Experimental e Tecnológica, Portugal
(...)
2018/04/09 - 2018/12/31 Postdoc (Research) Instituto de Biologia Experimental e Tecnológica, Portugal
Instituto de Biologia Experimental e Tecnológica, Portugal
(...)
2014/05 - 2017/09/21 Research Trainee (Research) Centro de Investigación Cooperativa en Biociencias, Spain
2011/05 - 2013/12/31 Research Trainee (Research) Centro de Investigación Cooperativa en Biociencias, Spain
Projects

Grant

Designation Funders
2024/11 - Current MPS NOVA Hub: Advanced Microphysiological Systems and Pluripotent Stem Cell Technologies to Unveil Chronic Disease Mechanisms and Host-Microbe Interactions
101159729
Researcher
European Union
Ongoing
2023/01/01 - Current SinTra: Workflows for single-cell transcriptomics in human cell-based bioprocesses and in vitro models
767
Researcher
Instituto de Biologia Experimental e Tecnológica
Ongoing
2022/01/01 - 2025/08/31 Cracking glycan-lectin interactions to target immunosuppressive macrophages in triple-negative breast cancer
PTDC/BTM-TEC/0432/2021
PTDC/BTM-TEC/0432/2021
Researcher
Instituto de Biologia Experimental e Tecnológica, Portugal

NOVA.ID.FCT - Associação para a Inovação e Desenvolvimento da FCT (NOVA.ID.FCT/FCTUNL/UNL), Portugal

Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/03 - 2025/02/28 Deciphering immunosuppressive events in Diffuse Midline Glioma (DMG) employing a 3D cell model of the tumor microenvironment
2022.02117.PTDC
Principal investigator
Instituto de Biologia Experimental e Tecnológica, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2022/05 - 2024/05 Development of a novel 3D cell model to study immunosuppressive events in Brain Cancer
PI - 752
Principal investigator
Instituto de Biologia Experimental e Tecnológica
Ongoing
2019/09/02 - 2021/05/31 3D-ABC: Long-term breast cancer 3D cell models as tools to study the potential of therapeutic antibodies
PI - 717 - 3d-abc
Principal investigator
Instituto de Biologia Experimental e Tecnológica, Portugal
 Instituto de Biologia Experimental e Tecnológica
Concluded

Contract

Designation Funders
2023/09/01 - Current Life Sciences for a Healthy and Sustainable Future
LA/P/0087/2020
10.54499/LA/P/0087/2020
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal

Universidade Nova de Lisboa Molecular Structural and Cellular Microbiology, Portugal

Universidade Nova de Lisboa, Portugal

Instituto de Biologia Experimental e Tecnológica, Portugal

Instituto Gulbenkian de Ciência, Portugal

Universidade de Lisboa Centro de Estudos Comparatistas, Portugal

BioResources 4 Sustainability, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2024/10/01 - 2026/09/30 Building a road map for Hematopoietic-Progenitor differentiation from human induced pluripotent stem cells (hiPSC): Towards novel cell tools for immunotherapy and immune competent preclinical models
P 785
Instituto de Biologia Experimental e Tecnológica, Portugal
 Instituto de Biologia Experimental e Tecnológica
2024/10 - 2026/09 Building a road map for Hematopoietic-Progenitor differentiation from human induced pluripotent stem cells (hiPSC): Towards novel cell tools for immunotherapy and immune competent preclinical models
P 785
 Instituto de Biologia Experimental e Tecnológica
2019/01/01 - 2021/10/31 Unraveling the role of astrocyte-induced neural microenvironment remodeling in traumatic brain injury pathobiology
PTDC/BTM-ORG/29580/2017
Researcher
Instituto de Biologia Experimental e Tecnológica, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2011/05/09 - 2013/12/31 Study of Breast Cancer stem cells in endocrine resistance
Contract
Research Technician Fellow
Centro de Investigación Cooperativa en Biociencias, Spain
 Centro de Investigación Cooperativa en Biociencias
Concluded
Outputs

Publications

Book chapter
  1. Domenici, Giacomo; Trindade, Gonçalo; Estrada, Marta F.; Cartaxo, Ana Luísa; Alves, Paula M.; André, Saudade; Brito, Catarina. "Patient-Derived Breast Cancer Tissue Cultures for Anti-Endocrine Drug Assays". In Methods in Molecular Biology, 11-31. Springer US, 2022.
    10.1007/978-1-0716-2513-2_2
Conference abstract
  1. Batalha, Sofia; Trindade, Gonçalo; Filipa Moura; Mariana Antunes; Domenici, Giacomo; GOMES-ALVES, Patrícia; Jose Escandell; Catarina Brito ; Inês A Isidro. Corresponding author: Inês A Isidro. "Workflows for SINgle-cell TRAnscriptomics in human cell-based bioprocesses and in vitro models". Paper presented in iBETXplore Day 2024, Oeiras, 2024.
  2. Sá, Inês; Gomes, Catarina; Domenici, Giacomo; Catarina Brito . Corresponding author: Catarina Brito. "A stem cell-derived 3D model to study human microglia dynamics". Paper presented in 2023 ETRS & SPCE-TC Annual Meeting, Coimbra, 2024.
    Published
  3. Domenici, Giacomo; Trindade, Gonçalo; Lopes, Nuno; Cartaxo, Ana L; Miret Minard, Joan; Catarina Brito . Corresponding author: Catarina Brito. "A platform of reconstructed 3D cell models of the Tumor Microenvironment to address antibody-based therapies". Paper presented in Dechema 3D Cell Culture 2023: Models, Applications & Translation, Freiburg, 2023.
Conference paper
  1. Batalha, Sofia; Domenici, Giacomo; Lopes, Nuno; Catarina Brito . Corresponding author: Catarina Brito. "3D heterotypic culture systems to study immune modulation and antibody response in HER2+ breast cancer microenvironment". Paper presented in 15TH ASPIC INTERNATIONAL CONGRESS, Porto, 2022.
Conference poster
  1. Domenici, Giacomo; Lopes, Nuno; Batalha, Sofia; Trindade, Gonçalo; Ramella Gal, Isabella; Freitas, Catarina; Duarte, Nádia; Brito, Catarina. Corresponding author: Brito, Catarina. "A Modular Platform of Reconstructive 3D Cell Models of Tumor Microenvironments to Evaluate Anibody-Based Therapies". Paper presented in iBETXplore Day 2025, 2025.
  2. Batalha, Sofia; Trindade, Gonçalo; Filipa Alves Moura; Antunes, Mariana; Domenici, Giacomo; Jose Escandell; GOMES-ALVES, Patrícia; Catarina Brito ; Inês A Isidro. Corresponding author: Inês A Isidro. "Tailored Single-Cell RNA-Seq Pipelines: From Experimental Design to Gene Targets in rAAV Production and Breast Cancer Response Biomarkers". Paper presented in Festival of Genomics and Biodata, 2025.
  3. Inês Quinteiro de Sá; Domenici, Giacomo; Gomes, Catarina; Jose Escandell Planells; Catarina Brito . Corresponding author: Catarina Brito. "Novel 3D human cell models to decipher the high-grade glioma tumor microenvironment". Paper presented in 6th ASPIC International Congress, 2024.
  4. Domenici, Giacomo. "3D Models of Immunosuppressive Breast Tumor Microenvironment to Evaluate Novel Antibody-Based Therapies". Paper presented in "III ASPIC-ASEICA International Meeting - Cancer Immunology, Tumor Microenvironment and Metastasis, 2023.
  5. Domenici, Giacomo; Lopes, Nuno; Correia, Viviana G.; Trindade, Gonçalo; Palma, Angelina S.; Catarina Brito . Corresponding author: Catarina Brito. "Screening the triple negative breast cancer cell glycome to target immunosuppression mediated by tumour-associated macrophages". Paper presented in III ASPIC-ASEICA International Meeting - Cancer Immunology, Tumor Microenvironment and Metastasis, 2023.
  6. Ramella Gal, Isabella; Arez, Francisca; Siofia Fernandes; Domenici, Giacomo; P. Correia, Inês; Duarte, Nádia; Catarina Freitas; et al. "Towards human innate immune-competent 3D hepatic models to address early tissue response to therapeutic AAV vectors". Paper presented in ESGCT - 30th ANNUAL CONGRESS, 2023.
  7. Domenici, Giacomo. "A 3D Culture Platform to Represent the Immune Microenvironment in Breast Cancer and its Modulation by Advanced Therapies". Paper presented in 27th European Society for Animal Cell technology (ESACT 2022), 2022.
  8. Domenici, Giacomo. "Patient-derived models of the tumor microenvironment for drug response evaluation and biomarker discovery - enabling tools to advance precision medicine". Paper presented in 27th European Society for Animal Cell technology (ESACT 2022), 2022.
  9. Trindade, Gonçalo; Miret Minard, Joan; Domenici, Giacomo; Cairó Badillo, Jordi Joan; Catarina Brito. "Pre-Clinical Evaluation of Antibody-Drug Conjugates In a 3D Breast Cancer Model". Paper presented in 27th Porto Cancer Meeting, 2021.
  10. Trindade, Gonçalo; Domenici, Giacomo; Joan Miret Minard; Jordi Joan Cairó Badillo; Catarina Brito. "Pre-clinical evaluation of HER2-Targeted Antibody-Drug conjugates using an in vitro Breast Cancer 3D cell model". Paper presented in 27th Porto cancer Meeting: Stemness and metastasis, 2020.
  11. Domenici, Giacomo; Gorka Orive; Ángel Montero Carcaboso; Catarina Brito. "A new Ewing's Sarcoma 3D cell model, which preserves long-term cell viability and enables ECM deposition and drug testing". Paper presented in EACR-AACR-ASPIC Conference: Tumor Microenvironment, 2020.
  12. Domenici, Giacomo; Gonçalo Trindade; Joan Miret Minard; Ana Luisa Cartaxo; Marta Estrada; Ruben Roque; Jordi Joan Cairó Badillo; Saudade André; Catarina Brito. "A 3D cell model platform to analyze the potential of novel targeted therapy modalities for Breast Cancer". Paper presented in EACR-AACR-ASPIC Conference: Tumor Microenvironment, 2020.
  13. Batalha, Sofia; Domenici, Giacomo; Lopes, Nuno. "Exploring NK cell engagement in 3D cell models of HER2+ breast cancer microenvironment". Paper presented in EACR-AACR-ASPIC: Tumor Microenvironment, 2020.
  14. Domenici, Giacomo; Marta Estrada; Ana Luisa Cartaxo; Ruben Roque; Saudade André; Catarina Brito. "A Breast Cancer microenvironment ex vivo model that preserves ERa signalling". Paper presented in Champalimaud Research Symposium 2019: Tissue microenvironment in health and disease, 2019.
  15. Lopes, Nuno; Cartaxo, Ana; Pinto, Catarina; Domenici, Giacomo; Rebelo, Sofia; Oliveira, Maria José; Brito, Catarina. "A 3D cell model to depict macrophage modulation in breast cancer microenvironment". Paper presented in 3rd Symposium of Immunomodulation in Cancer and Regeneration - Tcells and immunotherapies, 2019.
  16. Domenici, Giacomo; Marta Estrada; Ana Luisa Cartaxo; Ruben Roque; Saudade André; Catarina Brito. "An ex vivo tumour culture platform for functional drug testing". Paper presented in 26 th European Society for Animal Cell technology (ESACT 2019), 2019.
  17. Lopes, Nuno; Cartaxo, Ana; Pinto, Catarina; Domenici, Giacomo; Rebelo, Sofia; Oliveira, Maria José; Brito, Catarina. "Exploiting 3D cell-based models to recapitulate Breast Cancer-Macrophage crosstalk". Paper presented in Defence is the Best Attack: Immuno-Oncology Breakthroughs, 2019.
  18. Domenici, Giacomo. "Sox9 in normal and breast cancer stem cells". Paper presented in THe 7th EMBO Meeting, 2016.
  19. Domenici, Giacomo; Bruno Simöes; Miriam Rábano; Iskander Aurrekoetxea; Jessica Cellot; Iñaki Zabalza; María del Mar Vivanco. "Sox9 in normal and breast cancer stem cells". Paper presented in 15 th ASEICA INTERNATIONAL CONGRESS, 2015.
Journal article
  1. Domenici, Giacomo; Lopes, Nuno F.; Trindade, Gonçalo; Ramella Gal, Isabella; Miret Minard, Joan; Rebelo, Sofia P.; Freitas, Catarina; Duarte, Nádia; Brito, Catarina. "Assessing Novel Antibody-Based Therapies in Reconstructive 3D Cell Models of the Tumor Microenvironment". Advanced Biology (2024): https://doi.org/10.1002/adbi.202400431.
    10.1002/adbi.202400431
  2. Megan Cox; Rita Mendes; Kathleen N. Halwachs; Giacomo Domenici; Catarina Brito; Erwin R. Boghaert. "Tackling the tumor microenvironment – how can complex tumor models in vitro aid oncology drug development?". Expert Opinion on Drug Discovery 18 7 (2023): 753-768. http://dx.doi.org/10.1080/17460441.2023.2216016.
    10.1080/17460441.2023.2216016
  3. Teresa Franchi-Mendes; Rodrigo Eduardo; Giacomo Domenici; Catarina Brito. "3D Cancer Models: Depicting Cellular Crosstalk within the Tumour Microenvironment". Cancers 13 18 (2021): 4610-4610. https://doi.org/10.3390/cancers13184610.
    Published • 10.3390/cancers13184610
  4. Sales-Dias, Joana; Ferreira, Andreia; Lamy, Márcia; Domenici, Giacomo; Monteiro, Sandra M.S.; Pires, António; Lemos, Ana R.; et al. "Development of antibodies against the notch ligand Delta-Like-1 by phage display with activity against breast cancer cells". New Biotechnology 64 (2021): 17-26. http://dx.doi.org/10.1016/j.nbt.2021.05.003.
    10.1016/j.nbt.2021.05.003
  5. Gabriela Silva; Joana Sales-Dias; Diogo Casal; Sara Alves; Giacomo Domenici; Clara Barreto; Carolina Matos; et al. "Development of Dl1.72, a Novel Anti-DLL1 Antibody with Anti-Tumor Efficacy against Estrogen Receptor-Positive Breast Cancer". Cancers 13 16 (2021): 4074-4074. https://doi.org/10.3390/cancers13164074.
    10.3390/cancers13164074
  6. Domenici, Giacomo; Eduardo, Rodrigo; Castillo-Ecija, Helena; Orive, Gorka; Carcaboso, Ángel Montero; Brito, Catarina. "PDX-Derived Ewing's Sarcoma Cells Retain High Viability and Disease Phenotype in Alginate Encapsulated Spheroid Cultures". Cancers 13 4 (2021): 879. http://dx.doi.org/10.3390/cancers13040879.
    Open access • Published • 10.3390/cancers13040879
  7. Cartaxo, Ana Luísa; Estrada, Marta F.; Domenici, Giacomo; Roque, Ruben; Silva, Fernanda; Gualda, Emilio J.; Loza-Alvarez, Pablo; et al. "A novel culture method that sustains ERa signaling in human breast cancer tissue microstructures". Journal of Experimental & Clinical Cancer Research 39 1 (2020): http://dx.doi.org/10.1186/s13046-020-01653-4.
    10.1186/s13046-020-01653-4
  8. Domenici, Giacomo; Aurrekoetxea-Rodríguez, Iskander; Simões, Bruno M.; Rábano, Miriam; Lee, So Young; Millán, Julia San; Comaills, Valentine; et al. "A Sox2-Sox9 signalling axis maintains human breast luminal progenitor and breast cancer stem cells". Oncogene 38 17 (2019): 3151-3169. http://dx.doi.org/10.1038/s41388-018-0656-7.
    10.1038/s41388-018-0656-7
  9. Al Shareef, Zainab; Kardooni, Hoda; Murillo-Garzón, Virginia; Domenici, Giacomo; Stylianakis, Emmanouil; Steel, Jennifer H.; Rabano, Miriam; et al. "Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1". Oncogene 37 39 (2018): 5305-5324. http://dx.doi.org/10.1038/s41388-018-0294-0.
    10.1038/s41388-018-0294-0
  10. Martín-Martín, Natalia; Piva, Marco; Urosevic, Jelena; Aldaz, Paula; Sutherland, James D.; Fernández-Ruiz, Sonia; Arreal, Leire; et al. "Stratification and therapeutic potential of PML in metastatic breast cancer". Nature Communications 7 1 (2016): http://dx.doi.org/10.1038/ncomms12595.
    10.1038/ncomms12595
  11. Iriondo, Oihana; Rábano, Miriam; Domenici, Giacomo; Carlevaris, Onintza; López-Ruiz, José Antonio; Zabalza, Ignacio; Berra, Edurne; Vivanco, Maria dM. "Distinct breast cancer stem/progenitor cell populations require either HIF1 alpha or loss of PHD3 to expand under hypoxic conditions". Oncotarget 6 31 (2015): http://dx.doi.org/10.18632/oncotarget.5564.
    Open access • 10.18632/oncotarget.5564
  12. Domenici, Giacomo; Rábano, Miriam; Piva, Marco; Iriondo, Oihana; Zabalza, Ignacio; López-Ruiz, José Antonio; Vivanco, María del Mar. "Hormone response of breast stem cells and tamoxifen resistance". Revista de Senología y Patología Mamaria 27 4 (2014): 149-156. http://dx.doi.org/10.1016/j.senol.2014.07.006.
    Published • 10.1016/j.senol.2014.07.006
  13. Buttari, Brigitta; Profumo, Elisabetta; Domenici, Giacomo; Tagliani, Angela; Ippoliti, Flora; Bonini, Sergio; Businaro, Rita; Elenkov, Ilia; Riganò, Rachele. "Neuropeptide Y induces potent migration of human immature dendritic cells and promotes a Th2 polarization". The FASEB Journal 28 7 (2014): 3038-3049. http://dx.doi.org/10.1096/fj.13-243485.
    10.1096/fj.13-243485
  14. Piva, Marco; Domenici, Giacomo; Iriondo, Oihana; Rábano, Miriam; Simões, Bruno M; Comaills, Valentine; Barredo, Inmaculada; et al. "Sox2 promotes tamoxifen resistance in breast cancer cells". EMBO Molecular Medicine 6 1 (2014): 66-79. http://dx.doi.org/10.1002/emmm.201303411.
    10.1002/emmm.201303411
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/06/24 3D cell models of the CNS: a focus on High grade Glioma modelling SelectBIO Organoids & Spheroids Europe 2025 Conference
SelectBIO (Montpellier, France)
2024/06/25 Tumor microenvironment 3D cell models to address therapeutic response Organoids and Spheroids Europe 2024 Conference
SelectBIO (Rotterdam, Netherlands)
2023/06 Cell Microenvironments to Address Disease and Therapeutic Response ORGAN MODELLING & 3D CELL CULTURE 2023 25 - 26 April 2023 | London, UK
Oxford Global (London, United Kingdom)
2023/04 A platform of reconstructed 3D cell models of the tumor microenvironment to address antibody-based therapies 3D Cell Culture 2023: Models, Applications & Translation
Dechema (Friburg, Germany)
2022/01/20 Establishment of PDX-derived Ewing's Sarcoma 3D cell cultures employing spheroid encapsulation EuSARC Online Meeting
EuSARC (Online Event)
2019/05/24 Exploiting 3D cell culture to model cellular microenvironment in disease Modeling normal and pathological organs ex vivo
Institute Gustave Roussy (Paris, France)
2018/12/06 Unravelling the role of CCL24 in NSCLC progression and tumor microenvironment Secretome With]Out[ Borders
University of Minho (Braga, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2025/01/01 - 2028/12/31 GlioIn3D - Engineering a translational human 3D model depicting invasion in immunosuppressive high-grade gliomas
Co-supervisor of Inês Quinteiro de Sá
 PhD Program in Molecular Biosciences (MolBioS) (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal

Instituto de Biologia Experimental e Tecnológica, Portugal
2022/09 - 2023/12 Thesis Title: "Exploring 3D human CNS models to decipher the glioblastoma tumor microenvironment"
Supervisor of Inês Quinteiro de Sá
 Biomedical Engeneering (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/09/09 - 2023/05/30 Thesis Titles: "Development of a 3D cell model to study brain cancer cells-microglia interaction"
Supervisor of Francisco de Castro Sobral
 Biochemistry for Health (Master)
Universidade Nova de Lisboa, Portugal
2019/10/01 - 2021/03/31 Thesis title "Pre-Clinical Evaluation of Targeted Therapies Using Breast Cancer 3D Cell Models"
Supervisor of Gonçalo Trindade
 Biochemistry for Health (Master)
Universidade Nova de Lisboa, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2020/11/23 - 2020/11/23 Participation in the Organoids With]Out[ Borders - Online Symposium, abstract presented: "Development of ex vivo models for cancer research", awarded with the prize for "Best Abstract"
Symposium
 Organoids With]Out[ Borders - Online Symposium
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2024/01/12 Jury of MSc thesis defense of the student Diogo Fernandes, entitled "LAMA2-CMD: establishment of a new gene therapy strategy using and in vitro model".
(Thesis) Main arguer
 Diogo Rodrigues Fernandes (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019/10/21 Jury of PhD Thesis defense of the student Joan Mire Minard, entitled: "Development of antibody based antitumor-therapies based on trastuzumab antibody drug conjugates immunocytokines and fragment conjugates"
(Thesis) Arguer
 Joan Miret Minard (PhD)
Universitat Autònoma de Barcelona, Spain

Ad Hoc journal article review

Journal title (ISSN) Publisher
2024 - Current Advanced Therapeutics (2366-3987) Wiley
2022 - Current Scientific Reports (2045-2322)
2021 - Current Gene Therapy ( 1476-5462) Nature

Association member

Society Organization name Role
2019/12/17 - Current ASPIC - Associação Portuguesa de Investigação em Cancro (Portuguese Association for Cancer Research) Member

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022 - Current Invited Lecturer in Curricular unit on Tools for Discovery and Preclinical Research - Class on Organotypic Tissue Models Biociências Moleculares (Doutoramento) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2022/11/22 - 2022/11/22 Advanced Training Course on New In Vitro Models: Alternatives to Animal Models in Research - Online Class on "3D Models of High-Grade Gliomas" (Especialização pós-licenciatura) NOVA Medical School| Faculty of Medical Sciences University of Lisbon, Portugal
2021/05/13 - 2021/05/13 In vitro models for biomedical research - Online Lesson given to students of the course of Medicine from the NOVA Medical School, Faculty of Medical Sciences, University of Lisbon (Mestrado integrado) NOVA Medical School| Faculty of Medical Sciences University of Lisbon, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2019 - Current Evaluator in poster session and presentations for ITQB PhD student Meeting, at the University NOVA de Lisboa
Evaluator
 Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal

Mentoring / Tutoring

Topic Student name
2019/04/01 - 2019/04/08 Mentoring Lab Rotation MSc course Biochemistry for health- (NOVA University of Lisbon) Gonçalo Trindade

Other jury / evaluation

Activity description Institution / Organization
2021/06/30 - 2021/06/30 Jury of Report of Project in Cell and Molecular Biology of the Student Telma Alexandra Cataluna Abreu, entitled: "Establishing standard procedures to study the inflammation process in THP-1 macrophages and PMM2-CDG fibroblasts" NOVA SCHOOL OF SCIENCE AND TECHNOLOGY | FCT NOVA, Portugal
Distinctions

Award

2020 Best Abstract
Honourable Mention for Best abstract at the symposium "Organoids]Without[Borders, sponsored by the Young Scientist Forum (YSF) of the European Society for Biomaterials (ESB)., Portugal
2019 Travel Grant to participate to the 27th ESACT Meeting
European Society For Animal Cell Technology, Germany