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Teresa Esteves finished her PhD in Inorganic Chemistry, by the University of Lisbon (UL), in 2011 and concluded her Degree in Technological Chemistry, at the Faculty of Sciences from UL (FCUL), in 2004. Presently, she is a Contracted Researcher and Invited Assistant Professor at the Department of Bioengineering in IST. During her PhD she gained knowledge in the fields of Inorganic and Radiopharmaceutical Chemistry focusing on the development of targeted radioprobes for cancer diagnostic and therapy. Her current work is focused on the development of highly specific materials for novel materials discovery and applications, spanning from challenging separations to targeted drug release relying on molecularly imprinted polymers (MIPs), high affinity adsorbers and functionalized PEDOT nanoparticles. After completing her PhD, she continued expanding her knowledge and skills in different fields: development of small molecules as transmembrane transporters and cytotoxicity studies at FCUL and, since the beginning of 2014, at IST, she develops her research in the field of process separation, where she was the leader of a research project, funded by FCT (PTDC/QEQ-PRS/4157/2014, SelectHost: Innovative and efficient platforms for the removal of genotoxic impurities) under the scope of active pharmaceutical ingredient (API) purification, targeting genotoxic impurity removal with MIPs and polybenzimidazole (PBI) modified polymers, which work was well received by the scientific community, in several oral presentations in national and international conferences. Teresa Esteves also engaged in new challenges, addressing water resources recycling in food industry, and waste valorisation with isolation of molecules of interest to the pharmaceutical industry, with emphasis on new separation processes using nanofiltration membranes, commercial adsorbers and MIP development. The research work developed so far has resulted in several published scientific papers and two national and one international patent applications. She has also engaged in the co-supervision of PhD students, in Chemical Engineering and in Bioengineering, and in the supervision of several MSc students (Bioengineering and Nanosystems, Biological Engineering, Pharmaceutical Engineering, Biotechnology). Overall, her research is focused on the development of novel materials (adsorbers, MIPs, organic solvent nanofiltration membranes) and separation processes to meet challenging separations in the Pharma and Food industries and for targeted drug release using some of these platforms.
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Identification

Personal identification

Full name
Teresa Sofia Araújo Esteves

Citation names

  • Esteves, Teresa

Author identifiers

Ciência ID
341C-8B25-64EF
ORCID iD
0000-0003-0440-3619
Researcher Id
I-4696-2015
Scopus Author Id
6507729218

Email addresses

  • teresa.esteves@tecnico.ulisboa.pt (Professional)

Telephones

Telephone
  • 218419167 Ext.: 3167 (Professional)

Addresses

  • iBB-Institute for Bioengineering and Biosciences / Department of Bioengineering / Instituto Superior Técnico. Av. Rovisco Pais, 1, 1049-001, Lisboa, Lisboa, Portugal (Professional)

Websites

Knowledge fields

  • Engineering and Technology - Chemical Engineering - Chemical Engineering
  • Engineering and Technology - Materials Engineering
  • Engineering and Technology - Nano-technology - Nano-materials
  • Exact Sciences - Chemical Sciences - Polymer Science
  • Exact Sciences - Chemical Sciences - Organic Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Portuguese (Mother tongue)
Education
Degree Classification
2011/07/26
Concluded
 Doutoramento (Doutoramento)
Major in Química Inorgânica
Universidade de Lisboa Faculdade de Ciências, Portugal
"Complexos de elementos emissores de radiação gama e de electrões Auger para diagnóstico e/ou terapia do cancro." (THESIS/DISSERTATION)
 Distinção e Louvor.
2004/07/29
Concluded
 Química Tecnológica (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Optimização do Funcionamento de uma ETAR Industrial." (THESIS/DISSERTATION)
 16
Affiliation

Science

Category
Host institution 		Employer
2018/10/01 - Current Contracted Researcher (Research) Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2017/09/01 - 2018/09/30 Postdoc (Research) Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2014/03/10 - 2015/12/31 Postdoc (Research) Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Others

Category
Host institution 		Employer
2018/09/01 - 2023/08/31 Invited Assistant professor Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016/05/01 - 2017/08/31 Visiting Scientist Fellow Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2012/01/01 - 2013/12/31 Research Fellowship Universidade de Lisboa Centro de Química e Bioquímica, Portugal
2011/05/02 - 2011/10/31 Research Fellowship Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
2007/01/01 - 2010/12/31 PhD student Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
2009/05/04 - 2009/07/28 Visiting Scholar Harry S. Truman Memorial Veterans' Hospital, United States
2005/10/03 - 2006/12/29 Research Fellowship Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
2005/04/01 - 2005/06/30 Research Fellowship Universidade de Lisboa Instituto Superior Técnico, Portugal
2005/02/01 - 2005/03/31 Trainee Laboratório Militar de Produtos Químicos e Farmacêuticos, Portugal
2003/10/01 - 2004/07/30 Trainee Salvador Caetano IMVT, SA, Portugal
Projects

Grant

Designation Funders
2014/03/10 - 2015/12/31 GenoSep: Removal of Genotoxic Impurities from Active Pharmaceutical Ingredients
PTDC/QEQ-PRS/2757/2012
Post-doc Fellow
Universidade de Lisboa Instituto Superior Técnico, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2012/01/01 - 2013/12/31 Development of azacalix(hetero)arene transporters for mediated anionic flux across membranes: a novel approach for studying ionic passive difusion
PTDC/QUI-QUI/101022/2008
Research Fellow
Universidade de Lisboa Centro de Química e Bioquímica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011/05/02 - 2011/11/30 Targeting telomerase inhibition with new anti-tumural Cu(II) complexes
PTDC/QUI-QUI/114139/2009
Research Fellow
Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/10/03 - 2006/12/29 Novel metal fragments potentially useful for labeling with Tc and/or Re biologically relevant molecules
POCI/QUI/58245/2004
Research Fellow
Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2016/05/01 - 2018/10/31 SelectHost: Innovative and efficient platforms for the removal of genotoxic impurities
PTDC/QEQ-PRS/4157/2014
Principal investigator
Universidade de Lisboa Instituto Superior Técnico, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Stella Parmaki; Frederico C. Ferreira; Esteves, Teresa; Carlos A.M. Afonso; Koutinas, Michalis. "Sustainable chemical and biological technologies for the production of enantiopure added-value molecules in biorefineries". In Circular Bioeconomy: Technologies for Biofuels and Biochemicals, edited by Sunita Varjani; Ashok Pandey,; Thallada Bhaskar; S.Venkata Mohan; Daniel C.W. Tsang, 295-335. Elsevier, 2021.
    Published
Conference abstract
  1. Esteves, Teresa; F. Marques; J. Rino; A. Paulo; C. J. Smith; I. Santos. "Trifunctional Tricarbonyl Complexes for Cell-Specific and Nuclear Targeting". Paper presented in International Symposium on Technetium and Other Radiometals in Chemistry and Medicine (TERACHEM 2010), Nuclear Medicine and Biology, Bressanone, 2010.
    Published
Conference paper
  1. Esteves, Teresa; F. Marques; J. Rino; A. Paulo; C. J. Smith; I. Santos. "Trifunctional Tricarbonyl Complexes for Cell-Specific and Nuclear Targeting". Paper presented in Technetium and Other Radiometals in Chemistry and Medicine (TERACHEM 2010), Bressanone, 2010.
  2. P. Antunes; Esteves, Teresa; P. Raposinho; I. Santos. "Radiolabelled Short Neuropeptide Y Derivatives with Bifunctional Chelators for Breast Cancer". Paper presented in Technetium and Other Radiometals in Chemistry and Medicine (TERACHEM 2010), Bressanone, 2010.
Conference poster
  1. Filipe Miguel; Leonor Resina; Alberte, Paola; Esteves, Teresa; Ferreira, Frederico Castelo; João silva. Corresponding author: Filipe Miguel. "Biomimetic conductive hydrogel loaded with kartogenin-PEDOT nanoparticles for cartilage tissue engineering". Paper presented in European Orthopaedic Research Society (EORS) 2023 Meeting, 2023.
  2. Leonor Resina; K. El Hauadi; J. Sans; Esteves, Teresa; Ferreira, Frederico Castelo; M.M. Pérez-Madrigal; Alemán, Carlos. "Multiresponsive hydrogel as carrier for controlled chloramphenicol release". Paper presented in ACS Fall 2023, 2023.
  3. Leonor Resina; K. El Hauadi; Esteves, Teresa; Ferreira, Frederico Castelo; M.M. Pérez-Madrigal; Alemán, Carlos. "Dendritic self-assembled structures from anticancer pentapeptides". Paper presented in ACS Fall 2023, 2023.
  4. Catarina Franco Jones; A. Jain; Rawson, Frankie; Ferreira, Frederico Castelo; Esteves, Teresa; Sanjuan Alberte, Paola. "Multifunctional nanoparticles to enable novel wireless nanobioelectronics for cancer therapeutics". Paper presented in Cambridge Bioelectronics Symposium, 2023.
  5. Leonor Resina; Fábio F. F. Garrudo; Alemán, Carlos; Esteves, Teresa; Ferreira, Frederico Castelo. "Nanomaterial-based wireless electrostimulation platform for cancer treatment". Paper presented in Advanced Functional Polymers for Medicine (AFPM) 2023, 2023.
  6. Leonor Resina; El Hauadi, Karima; J. Sans; Esteves, Teresa; Ferreira, Frederico Castelo. "Electro-Responsive and pH-Sensitive Hydrogel as Carrier for Controlled Drug Release". Paper presented in Advanced Functional Polymers for Medicine (AFPM) 2023, 2023.
  7. Filipe Miguel; Leonor Resina; Sanjuan Alberte, Paola; Esteves, Teresa; Ferreira, Frederico Castelo; João C. Silva. Corresponding author: João C. Silva. "Electrically conductive hydrogel loaded with Kartogenin-PEDOT nanoparticles for articular cartilage regeneration.". Paper presented in TERMIS-EU 2023, 2023.
  8. Resina, Leonor; Fábio F. F. Garrudo; Alemán, Carlos; Esteves, Teresa; Ferreira, Frederico Castelo. Corresponding author: Resina, Leonor. "Wireless electrostimulation for cancer treatment using an integrated nanoparticle/coaxial fiber mesh platform". Paper presented in 2nd iBB Workshop, 2022.
  9. Esteves, Teresa; Flávio A. Ferreira; Ana T. Mota; Barbeitos, Catarina; Andrade, Késsia; Carlos A.M. Afonso; Frederico C. Ferreira. Corresponding author: Esteves, Teresa. "A molecular imprinting polymer (MIP) for the isolation of lupanine coupled to nanofiltration and solvent extraction". Paper presented in Affinity 2021, 2021.
  10. Esteves, Teresa; S. Battello; A. Mota; C. A. M. Afonso; F. Malpei; D. Scaglione; F. C. Ferreira. "Membrane Process for Water Recycle and Lupanine Recovery on Lupin Bean Processing: Preliminary Results". Paper presented in Euromembrane 2018, 2018.
  11. C. B. M. Barbeitos; A. T. A. P. Mota; Esteves, Teresa; R. Teixeira; C. A. M. Afonso; F. C: Ferreira. "Lupanine Removal from Lupin Beans Detoxification Wastewater". Paper presented in XXV Encontro Nacional da SPQ, 2017.
  12. Esteves, Teresa; A. Parente; C. A. M. Afonso; F. C. Ferreira. "Biorg4WasteWaterVal+: Chiral Molecularly Imprinted Polymers for Enantioseparation of Lupanine". Paper presented in Workshop: "Closing the loop on valorization of food processing wastewater containing alkaloids: the lupanine case", 2017.
  13. F. A. Ferreira; Esteves, Teresa; F. C. Ferreira. "Hybrid Process for Genotoxics Removal from Active Pharmaceutical Ingredients Combining Organic Solvent Nanofiltration with Polybenzimidazole Adsorbents". Paper presented in Separations Technology IX: New Frontiers in Media, Techniques, and Technologies, 2017.
  14. F. A. Ferreira; Esteves, Teresa; F. C. Ferreira. "Polybenzimidazole Polymer Conditioning for Genotoxic Impurities Removal from Active Pharmaceutical Ingredients Post Reaction Streams". Paper presented in II Jornadas de Caracterização de Materiais, 2017.
  15. A. I. Vicente; Esteves, Teresa; F. C. Ferreira; C. A. M. Afonso. "Functionalization of PBI with an Adenine Derivative for API Purification". Paper presented in 19th European Symposium on Organic Chemistry (ESOC 2015), 2015.
  16. Esteves, Teresa; F. C. Ferreira. "New Porous Materials for the Selective Removal of Genotoxic Impurities from Active Pharmaceutical Ingredients". Paper presented in XXIV Encontro Nacional da SPQ, 2015.
  17. J. M. Caio; Esteves, Teresa; V. Félix; C. Moiteiro. "Design of Small-molecules for Transmembrane Anion Transport". Paper presented in CQB-day 2014, 2014.
  18. J. M. Caio; A. I. Vicente; M. M. Santos; Esteves, Teresa; S. Carvalho; C. Moiteiro; V. Félix. "Synthesis, Characterization and Binding Studies of Functionalized Azacalix[2]arene[2]triazine Receptors for Biological Applications". Paper presented in CQB-day 2013, 2013.
  19. Esteves, Teresa; J. M. Caio; M. M. Santos; A. I. Vicente; C. Moiteiro; S. Carvalho; V. Félix. "Functionalized Azacalix[2]arene[2]triazine for the Recognition of Relevant Biological Anions". Paper presented in XXIII Encontro Nacional da SPQ, 2013.
  20. C. Moiteiro; Esteves, Teresa; R. Rojas; S. L. Alvarez; S. A. Zacchino; H. Bragança. "Bio-valorization of Azorean Cryptomeria Japonica Essential Oils". Paper presented in 43rd International Symposium on Essential Oils (ISEO 2012), 2012.
  21. J. M. Caio; Esteves, Teresa; S. Carvalho; C. Moiteiro; V. Félix. "New Azacalix[2]arene[2]triazine Derivatives and Complexation Studies with Cu (II)". Paper presented in 13th Belgian Organic Synthesis Symposium (BOSS XIII), 2012.
  22. J. M. Caio; Esteves, Teresa; S. Carvalho; C. Moiteiro; V. Félix. "Novel Azacalix[2]arene[2]triazine Receptors Functionalized on the Nitrogen Bridging Atoms: Coordination Studies Towards Cu (II)". Paper presented in 6th Spanish-Portuguese-Japanese Organic Chemistry Symposium, 2012.
  23. Esteves, Teresa; F. Marques; J. Rino; A. Paulo; C. J. Smith; I. Santos. "Specific Multifunctional fac-[M(CO)3]+ (M = Re, 99mTc) Complexes Directed to the Nucleus of Targeted Cells". Paper presented in COST D38 Final Conference, Final MC and Evaluation Meeting, 2011.
  24. Esteves, Teresa; F. Marques; J. Rino; A. Paulo; C. J. Smith; I. Santos. "Complexos Específicos Trifuncionais de [99mTc(CO)3]+ Direccionados ao Núcleo de Células Alvo". Paper presented in Ciência QB - 1º Encontro dos Alunos de Doutoramento do DQB - FCUL, 2011.
  25. Esteves, Teresa; F. Marques; J. Rino; A. Paulo; C. J. Smith; I. Santos. "Trifunctional Tricarbonyl Complexes for Cell-Specific and Nuclear Targeting". Paper presented in Technetium and Other Radiometals in Chemistry and Medicine (TERACHEM 2010), 2010.
  26. Esteves, Teresa; F. Marques; J. Rino; A. Paulo; C. J. Smith; I. Santos. "Trifunctional Tricarbonyl Complexes for Cell-Specific and Nuclear Targeting". Paper presented in COST D38 WG3-5 joint meeting “Metal-based Systems for Molecular Imaging Applications”, 2010.
  27. Esteves, Teresa; S. Gama; F. Mendes; F. Marques; A. Paulo; J. Pessoa; J. Rino; I. Santos. "Rhenium Tricarbonyl Complexes Bearing an Acridine Orange Moiety: Synthesis and DNA Interaction Studies". Paper presented in Encontro com a Ciência e Tecnologia em Portugal, 2010.
  28. Esteves, Teresa; S. Gama; F. Mendes; F. Marques; A. Paulo; J. Pessoa; J. Rino; I. Santos. "Rhenium Tricarbonyl Complexes Bearing an Acridine Orange Moiety: Synthesis and DNA Interaction Studies". Paper presented in 10th International Symposium on Applied Bioinorganic Chemistry (ISABC 10), 2009.
  29. Esteves, Teresa; C. Xavier; S. Gama; F. Marques; A. Paulo; G. G. Martins; J. C. Pessoa; G. Viola; I. Santos. "Tricarbonyl Complexes Containing Acridine Fluorophores for Multimodal Imaging". Paper presented in World Molecular Imaging Congress (WMIC 2008), 2008.
  30. Esteves, Teresa; C. Xavier; F. Marques; A. Paulo; G. G. Martins; I. Santos. "Rhenium (I) Tricarbonyl Complexes Bearing Acridine Moieties: Synthesis, Characterization and Fluorescence Imaging Studies". Paper presented in 7ª Conferências de Química Inorgânica, 2007.
  31. Esteves, Teresa; M. P. C. Campelo; A. Paulo; I. Santos. "Rhenium (V) Complexes Anchored on Cyclen Ligands". Paper presented in 8th European Biological Inorganic Chemistry Conference (EUROBIC 8), 2006.
Journal article
  1. Resina, Leonor; Garrudo, Fábio F.F.; Alemán, Carlos; Esteves, Teresa; Ferreira, Frederico Castelo. Corresponding author: Esteves, Teresa. "Wireless electrostimulation for cancer treatment: An integrated nanoparticle/coaxial fiber mesh platform". Biomaterials Advances 160 (2024): 213830. http://dx.doi.org/10.1016/j.bioadv.2024.213830.
    Published • 10.1016/j.bioadv.2024.213830
  2. Resina, Leonor; Alemán, Carlos; Ferreira, Frederico Castelo; Esteves, Teresa. Corresponding author: Esteves, Teresa. "Protein-imprinted polymers: How far have “plastic antibodies” come?". Biotechnology Advances 68 (2023): 108220. http://dx.doi.org/10.1016/j.biotechadv.2023.108220.
    Published • 10.1016/j.biotechadv.2023.108220
  3. Garrudo, Fábio F. F.; Filippone, Giulia; Resina, Leonor; Silva, João C.; Barbosa, Frederico; Ferreira, Luís F. V.; Esteves, Teresa; et al. Corresponding author: Ferreira, Frederico Castelo. "Production of Blended Poly(acrylonitrile): Poly(ethylenedioxythiophene):Poly(styrene sulfonate) Electrospun Fibers for Neural Applications". Polymers 15 13 (2023): 2760. http://dx.doi.org/10.3390/polym15132760.
    Open access • Published • 10.3390/polym15132760
  4. Resina, Leonor; El Hauadi, Karima; Sans, Jordi; Esteves, Teresa; Ferreira, Frederico Castelo; Pérez-Madrigal, Maria M.; Alemán, Carlos. "Electroresponsive and pH-Sensitive Hydrogel as Carrier for Controlled Chloramphenicol Release". Biomacromolecules (2023): http://dx.doi.org/10.1021/acs.biomac.2c01442.
    Published • 10.1021/acs.biomac.2c01442
  5. Faria, Nuno Torres; Nascimento, Miguel Figueiredo; Ferreira, Flávio Alves; Esteves, Teresa; Santos, Marisa Viegas; Ferreira, Frederico Castelo. "Substrates of Opposite Polarities and Downstream Processing for Efficient Production of the Biosurfactant Mannosylerythritol Lipids from Moesziomyces spp.". Applied Biochemistry and Biotechnology (2023): http://dx.doi.org/10.1007/s12010-023-04317-z.
    Published • 10.1007/s12010-023-04317-z
  6. Parmaki, Stella; Esteves, Teresa; Gonçalves, João M. J.; Catenacci, Arianna; Malpei, Franscesca; Ferreira, Frederico C.; Afonso, Carlos A. M.; Koutinas, Michalis. "Selective microbial resolution of lupanine racemate: Bioprocess development and the impact of carbon catabolite repression on industrial wastewater valorisation". Biomass Conversion and Biorefinery (2022): http://dx.doi.org/10.1007/s13399-022-03383-3.
    Published • 10.1007/s13399-022-03383-3
  7. El Hauadi, Karima; Resina, Leonor; Zanuy, David; Esteves, Teresa; Ferreira, Frederico Castelo; Pérez-Madrigal, Maria M.; Alemán, Carlos. "Dendritic Self-assembled Structures from Therapeutic Charged Pentapeptides". Langmuir 38 42 (2022): 12905-12914. http://dx.doi.org/10.1021/acs.langmuir.2c02010.
    Published • 10.1021/acs.langmuir.2c02010
  8. Esteves, Teresa; Ferreira, Flávio A.; Mota, Ana Teresa; Sánchez-González, Ángel; Gil, Adrià; Andrade, Késsia H. S.; Afonso, Carlos A. M.; Ferreira, Frederico Castelo. "Greener Strategy for Lupanine Purification from Lupin Bean Wastewaters Using a Molecularly Imprinted Polymer". ACS Applied Materials & Interfaces 14 16 (2022): 18910-18921. http://dx.doi.org/10.1021/acsami.2c02053.
    Open access • Published • 10.1021/acsami.2c02053
  9. Brás, Eduardo J. S.; Fortes, Ana Margarida; Esteves, Teresa; Chu, Virginia; Fernandes, Pedro; Conde, João Pedro. "Microfluidic device for multiplexed detection of fungal infection biomarkers in grape cultivars". The Analyst (2020): http://dx.doi.org/10.1039/d0an01753a.
    Published • 10.1039/d0an01753a
  10. Esteves, Teresa; Mota, Ana Teresa; Barbeitos, Catarina; Andrade, Késsia; Afonso, Carlos A.M.; Ferreira, Frederico Castelo. "A study on lupin beans process wastewater nanofiltration treatment and lupanine recovery". Journal of Cleaner Production 277 (2020): 123349. http://dx.doi.org/10.1016/j.jclepro.2020.123349.
    Published • 10.1016/j.jclepro.2020.123349
  11. Ferreira, Flávio; Resina, Leonor; Esteves, Teresa; Ferreira, Frederico Castelo. "Comparison and Combination of Organic Solvent Nanofiltration and Adsorption Processes: A Mathematical Approach for Mitigation of Active Pharmaceutical Ingredient Losses during Genotoxin Removal". Membranes 10 4 (2020): 73. http://dx.doi.org/10.3390/membranes10040073.
    Open access • Published • 10.3390/membranes10040073
  12. Flávio A. Ferreira; Esteves, Teresa; Marta P. Carrasco; João Bandarra; Carlos A. M. Afonso; Frederico C. Ferreira. "Polybenzimidazole for Active Pharmaceutical Ingredient Purification: The Mometasone Furoate Case Study". Industrial & Engineering Chemistry Research 58 (2019): 10524-10532. https://pubs.acs.org/doi/10.1021/acs.iecr.9b01285.
  13. Esteves, Teresa; Esteves, Teresa; Ferreira, Flávio A.; Pina, Mariana; Bandarra, João; Ferreira, Frederico Castelo. "Screening commercial available resins for simultaneous removal of two potential genotoxins from API methanolic streams". Separation Science and Technology 54 (2019): 3005-3018. http://dx.doi.org/10.1080/01496395.2018.1556304.
    Published • 10.1080/01496395.2018.1556304
  14. Teresa Esteves; Ana I. Vicente; Flávio A. Ferreira; Carlos A.M. Afonso; Frederico Castelo Ferreira. "Mimicking DNA alkylation: Removing genotoxin impurities from API streams with a solvent stable polybenzimidazole-adenine polymer". Reactive and Functional Polymers 131 (2018): 258-265. https://doi.org/10.1016/j.reactfunctpolym.2018.07.019.
    10.1016/j.reactfunctpolym.2018.07.019
  15. Ana I. Vicente; Esteves, Teresa; Carlos A. M. Afonso; Ferreira, Frederico Castelo. "Solvent compatible polymer functionalization with adenine, a DNA base, for API degenotoxification: Preparation and characterization". Separation and Purification Technology 179 (2017): 438-448. http://www.sciencedirect.com/science/article/pii/S1383586616326806.
    10.1016/j.seppur.2017.02.011
  16. Sara realista; Susana Quintal; Paulo N. Martinho; Ana I. Melato; Adriá Gil; Esteves, Teresa; Maria de Deus Carvalho; et al. "Electrochemical studies and potential anticancer activity in ferrocene derivatives". Journal of Coordination Chemistry 70 2 (2017): 314-327. http://www.tandfonline.com/doi/full/10.1080/00958972.2016.1257125.
    10.1080/00958972.2016.1257125
  17. Esteves, Teresa; Raquel Viveiros; João Bandarra; William Heggie; Teresa Casimiro; Frederico Castelo Ferreira. "Molecularly imprinted polymer strategies for removal of a genotoxic impurity, 4-dimethylaminopyridine, from an active pharmaceutical ingredient post-reaction stream". Separation Purification Technology 163 (2016): 206-214. http://ac.els-cdn.com/S138358661630048X/1-s2.0-S138358661630048X-main.pdf?_tid=94e07696-e515-11e5-867a-00000aacb35d&acdnat=1457431836_725e17fa5ceab0a48e92c4b3f109aa2a.
    10.1016/j.seppur.2016.01.053
  18. João M. Caio; Esteves, Teresa; Silvia Carvalho; Cristina Moiteiro; Vítor Félix. "Azacalix[2]arene[2]triazine-based receptors bearing carboxymethyl pendant arms on nitrogen bridges: synthesis and evaluation of their coordination ability towards copper (II)". Organic & Biomolecular Chemistry 12 (2013): 589-599. http://pubs.rsc.org/en/Content/ArticleLanding/2014/OB/c3ob42047g#!divAbstract.
    10.1039/c3ob42047g
  19. Cristina Moiteiro; Esteves, Teresa; Luís Ramalho; Rosario Rojas; Sandra Alvarez; Susana Zacchino; Helena Bragança. "Essential Oil Characterization of Two Azorean Cryptomeria japonica Populations and Their Biological Evaluations". Natural Product Communications 8 12 (2013): 1785-1790. https://journals.sagepub.com/doi/pdf/10.1177/1934578X1300801233.
    Published
  20. Gama, S.; Mendes, F.; Esteves, T.; Marques, F.; Matos, A.; Rino, J.; Coimbra, J.; et al. "Synthesis and Biological Studies of Pyrazolyl-Diamine PtII Complexes Containing Polyaromatic DNA-Binding Groups". ChemBioChem 13 16 (2012): 2352-2362. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868093608&partnerID=MN8TOARS.
    10.1002/cbic.201200472
  21. Esteves, T.; Marques, F.; Paulo, A.; Rino, J.; Nanda, P.; Smith, C.J.; Santos, I.. "Nuclear targeting with cell-specific multifunctional tricarbonyl M(I) (M is Re, 99mTc) complexes: Synthesis, characterization, and cell studies". Journal of Biological Inorganic Chemistry 16 8 (2011): 1141-1153. http://www.scopus.com/inward/record.url?eid=2-s2.0-84655169705&partnerID=MN8TOARS.
    10.1007/s00775-011-0803-x
  22. Moura, C.; Esteves, T.; Gano, L.; Raposinho, P.D.; Paulo, A.; Santos, I.. "Synthesis, characterization and biological evaluation of tricarbonyl M(i) (M = Re, 99mTc) complexes functionalized with melanin-binding pharmacophores". New Journal of Chemistry 34 11 (2010): 2564-2578. http://www.scopus.com/inward/record.url?eid=2-s2.0-78049263952&partnerID=MN8TOARS.
    10.1039/c0nj00256a
  23. Esteves, T.; Xavier, C.; Gama, S.; Mendes, F.; Raposinho, P.D.; Marques, F.; Paulo, A.; et al. "Tricarbonyl M(I) (M = Re, 99mTc) complexes bearing acridine fluorophores: Synthesis, characterization, DNA interaction studies and nuclear targeting". Organic and Biomolecular Chemistry 8 18 (2010): 4104-4116. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955948795&partnerID=MN8TOARS.
    10.1039/c0ob00073f
  24. Vitor, R.F.; Esteves, T.; Marques, F.; Raposinho, P.; Paulo, A.; Rodrigues, S.; Rueff, J.; et al. "99mTc-Tricarbonyl Complexes Functionalized with Anthracenyl Fragments: Synthesis, Characterization, and Evaluation of Their Radiotoxic Effects in Murine Melanoma Cells". Cancer Biotherapy and Radiopharmaceuticals 24 5 (2009): 551-563. http://www.scopus.com/inward/record.url?eid=2-s2.0-70449113426&partnerID=MN8TOARS.
    10.1089/cbr.2009.0647
Thesis / Dissertation
  1. Esteves, Teresa Sofia Araújo, 1981-. "Complexos de elementos emissores de radiação gama e de electrões Auger para diagnóstico e/ou terapia do cancro". PhD, 2011. http://hdl.handle.net/10451/3917.

Intellectual property

Patent
  1. Leonor Resina; Fábio F. F. Garrudo; Esteves, Teresa; Ferreira, Frederico Castelo. 2023. "Hidrogel eletrocondutor autoregenerável, suas composições, usos e métodos de obtenção".
    Pending
  2. Esteves, Teresa; Ferreira, Frederico Castelo; Vicente, Ana I.; Afonso, Carlos A. M.. 2017. "Polybenzimidazole polymer with functionalized spacer chain and its method of preparation for removal of genotoxic impurities".
  3. Esteves, Teresa; Ferreira, Frederico Castelo; Vicente, Ana I.; Afonso, Carlos A. M.. 2016. "Polímero de polibenzimidazolo com cadeia espaçadora funcionalizada e seu método de obtenção para remoção de impurezas genotóxicas".
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/10/27 Controlled therapeutic peptide release using nanoparticles and hydrogels Peptide Materials
(Sorrento, Italy)
2023/09/15 Material development contribution to improve biorefinery sustainability ChemPor 2023
(Bragança, Portugal)
2023/08/13 Using nanomaterials for cancer treatment: a wireless electrostimulation platform ACS Fall 2023
American Chemical Society (San Francisco, United States)
2023/04/25 Wireless electrostimulation nanomaterials platform for cancer treatment NanoSpain Conf 2023
Phantoms Foundation (Tarragona, Spain)
2023/03/28 Wireless electrostimulation for cancer treatment: an integrated nanoparticle/coaxial fiber mesh platform TERMIS-EU 2023
University of Manchester (Manchester, United Kingdom)
2022/09/23 Lupanine isolation from industrial wastewaters and purification with a functional molecularly imprinted polymer 2nd iBB Workshop
iBB (Lisbon, Portugal)
2022/07/23 Lupanine purification from lupin beans wastewaters using a functional molecularly imprinted polymer ANM 2022
University of Aveiro (Aveiro, Portugal)
2021/11/15 Lupanine recovery from industrial wastewaters 5th International Caparica Christmas Conference on Sample Treatment 2021
Proteomass Scientific Society (Almada)
2020/11/30 New PBI-adenine adsorber for API post-reaction stream purification 4 th International Caparica Christmas Conference on Sample treatment
Proteomass Scientific Society (Lisbon, Portugal)
2020/02/27 Biomimetic inspired materials for purification in pharmaceutical industry Polymer Connect 2020
polytechnic of Leiria (Lisbon, Portugal)
2019/10/14 Biomimetic adsorbers: adenine functionalised and imprinted polymers iBB Seminars
Institute of Bioengineering and Biosciences (Lisbon, Portugal)
2019/04/08 Membrane Process for Water Recycle and Lupanine Recovery on Lupin Bean Processing Engineering with Membranes
(Bastad, Sweden)
2018/07/09 Hybrid Process Diafiltration-Adsorption for Genotoxic Removal from Active Pharmaceutical Ingredient Post Reaction Streams Euromembrane 2018
European Membrane Society (Valencia, Spain)
2018/07 Hybrid Process OSN-Adsorption to Remove Genotoxic Impurities with Minimal Pharmaceutical Losses 16th NYM (Network Young Membrains) 2018
European Membrane Society (Valencia, Spain)
2017/07/19 Mimicking DNA Alkylation in Organic Solvent with an Adenine Functional Polymer for Genotoxins Removal from Pharmaceuticals International Conference on Advanced Polymer Materials and Nanocomposites
Universidade de Aveiro (Aveiro, Portugal)
2017/06/25 Mimicking DNA Alkylation to Develop a Scavenger Platform for API Degenotoxification in Organic Solvent Matrices Affinity 2017
International Society for Molecular Recognition (Paris, France)
2017/06/05 New Adsorbers for the Removal of Genotoxic Impurities from Active Pharmaceutical Ingredients iBB Spring Seminars
iBB (Lisboa, Portugal)
2017/03/05 New Adsorbers for the Removal of Genotoxic Impurities from Active Pharmaceutical Ingredients Separations Technology IX: New Frontiers in Media, Techniques, and Technologies
Engineering Conferences International (Albufeira, Portugal)
2015/09/27 New High Affinity Materials for the Selective Removal of Genotoxic Impurities from Active Pharmaceutical Ingredients Affinity 2015
International Society for Molecular Recognition (Puerto Vallarta, Mexico)
2010/02/10 New [99mTc(CO)3]+-Labeled Bombesin Conjugates Bearing an Acridine Orange Moiety for Diagnosis and/or Therapy of Cancer Iberian Peptide Meeting (EPI XII)
SPQ (Lisboa, Portugal)
2007/12/01 Multifunctional Organometallic Complexes for Fluorescence and Nuclear Imaging 7ª Conferências de Química Inorgânica - SPQ
SPQ (Fátima, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023/02/01 - Current In vitro studies of novel nanobioelectronics for cancer therapy
Co-supervisor of Diogo Dias
 Biomedical Engineering (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2023/02/01 - Current Development of novel nanobioelectronic systems for cancer therapy
Co-supervisor of Catarina Jones
 Biomedical Engineering (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/09/01 - Current Electroconductive polymeric nanoparticles for smart drug delivery: Tailoring drug-polymer interactions
Co-supervisor of Bernardo Pinho
 Bioengineering and nanosystems (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/01/02 - Current Molecular imprinting polymers as artificial antibodies.
Co-supervisor of José Pedro Sousa Oliveira
 Bioengenharia e Nanossistemas (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/01/01 - Current New electro-responsive materials platforms for cancer treatment: Smart self-growing nanoparticles and transdermal devices.
Co-supervisor of Leonor Resina
 Bioengineering (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/02/01 - 2023/07/03 Biostimulation as a strategy to valorize the effluent from the lupin bean industry
Co-supervisor of Filipa Rebelo
 Biological Engineering (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/09/01 - 2023/02/03 In vitro studies ofnovel nanobioelectronics for cancertherapy
Co-supervisor of Diogo Dias
 PIC2 - 2nd Cycle Integrated Project in Biomedical Engineering (Scientific initiation)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/09/01 - 2023/02/03 Development of novel nanobioelectronic systems for cancer therapy.
Co-supervisor of Catarina Jones
 PIC2 - 2nd Cycle Integrated Project in Biomedical Engineering (Scientific initiation)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/09/01 - 2022/11/22 Development of process and polymers for synephrine removal from sour orange juice.
Co-supervisor of Sofia Teles Gomes Raposo Bettencourt
Engenharia Química (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/01/01 - 2021/12/02 Studies on removal of genotoxic impurities from pharmaceuticals streams using polybenzimidazole membrane adsorbers
Co-supervisor of José Alexandre Monteiro Friande
 Master Degree in Pharmaceutical Engineering (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/01/01 - 2021/12/02 An Orange Biorefinery: process and economic assessment
Co-supervisor of Bruno Alexandre Oliveira Lobo
 Integrated Master Degree in Biological Engineering (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/09/01 - 2021/11/24 Removal of Added Value Alkaloids from Food Aqueous Streams
Co-supervisor of Ana Quintino
 Integrated Master Degree in Biotechnology (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/02/03 - 2020/04/30 Downstream separations using molecular imprinted polymers / membrane technology.
Co-supervisor of Evgeny Sankin
 Biomedical Laboratorium Technology and Chemistry (Degree)
Karel de Grote Hogeschool Antwerpen, Belgium
2015/03/01 - 2019/07/22 Remoção de Impurezas Genotóxicas de Princípios Activos Farmacêuticos
Co-supervisor of Flávio Alves Ferreira
 PhD Chemical Engineering (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/01/01 - 2017/12/15 Assessing Separation Processes for an Aromatic and a Chiral Amine Using Polybenzimidazole (PBI) Membranes
Co-supervisor of Sara Lopes
 MSc Bioengineering and Nanosystems (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/01/01 - 2017/12/15 Membrane/adsorption Hybrid Processes for Water Purification and Lupanine Isolation from Lupin Beans Debittering Wastewater
Co-supervisor of Ana Mota
 MSc Bioengineering and Nanosystems (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016/01/01 - 2016/12/15 Towards the Development of a Process for Lupin Beans Detoxification Wastewater with Lupanine Recovery
Co-supervisor of Catarina Barbeitos
 MSc Biological Engineering (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/07/07 - Current Enhancing professional skills for effective communication and conflict management
Workshop
 Enhancing professional skills for effective communication and conflict management
Kungliga Tekniska Högskolan Avdelningen för robotik perception och lärande, Sweden
2023/06/14 - Current Propriedade Intelectual
Workshop
 Propriedade Intelectual
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/07/20 - Current Desenvolvimento de competências pessoais e académicas
Seminar
 Desenvolvimento de competências pessoais e académicas
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/07/19 - Current Gestão do stress na carreira docente e programas de autocuidado
Workshop
 Gestão do stress na carreira docente e programas de autocuidado
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/07/13 - Current Redes sociais e comunicação de ciência para professores e investigadores
Workshop
 Redes sociais e comunicação de ciência para professores e investigadores
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/07/12 - Current Saúde mental no ensino superior - aquilo a que devemos estar atentos
Workshop
 Saúde mental no ensino superior - aquilo a que devemos estar atentos
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015/06/26 - Current II Analytical Chemistry Symposium: “Environmental Occurrence, Effects and Removal of Pharmaceuticals”
Symposium
 II Analytical Chemistry Symposium: “Environmental Occurrence, Effects and Removal of Pharmaceuticals”
Universidade de Aveiro, Portugal
2022/07/07 - 2022/07/08 Princípios de coaching aplicados à orientação de dissertações
Workshop
 Princípios de coaching aplicados à orientação de dissertações
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/02/26 - 2021/04/07 Ciclo de Formação – Laboratórios em Tempos de Pandemia, Ensino Experimental em Tempos de Pandemia Sessão 1 (26 February 2021), Sessão 2 (15 March 2021), Sessão 3 (7 Abril 2021)
Seminar
 Ciclo de Formação – Laboratórios em Tempos de Pandemia, Ensino Experimental em Tempos de Pandemia
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/09/14 - 2020/09/18 Course on Molecular Biomarkers and Technologies
Workshop
 Course on Molecular Biomarkers and Technologies
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/02/19 - 2020/02/20 Pedagogical skills for teaching assistants.
Workshop
 Pedagogical skills for teaching assistants.
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/02/14 - 2020/02/14 Primeira aula do semestre: dos e don'ts.
Workshop
 Primeira aula do semestre: dos e don'ts.
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/02/11 - 2020/02/11 O powerpoint não é mau, mas teve uma infância difícil.
Workshop
 O powerpoint não é mau, mas teve uma infância difícil.
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015/03/16 - 2015/03/24 How to design powerful experiments
Workshop
 How to design powerful experiments
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014/10/15 - 2014/10/17 Solid State NMR
Workshop
 Solid State NMR
Universidade de Lisboa Instituto Superior Técnico, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2021/12/07 Dual-Targeted Radiocomplexes for Prostate Cancer Theranostics.
(Thesis) Arguer
 Ana Rita Mosquito Julião (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018/07/12 Síntese de Estruturas Supramoleculares Baseadas em Unidades Aceitadoras/dadoras
(Thesis) Main arguer
 Marcos Bento (Other)
Universidade de Lisboa Faculdade de Ciências, Portugal
2017/09/22 Novel ceramic membranes for cell microfiltration: towards a new research and diagnostic tool
(Thesis) Main arguer
 Cátia Martins dos Santos (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016/11/16 Development of polydopamine coated membranes (fabrication, characterization and morphology)
(Thesis) Main arguer
 Rafaela dos Santos Tomé (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Association member

Society Organization name Role
2016/06/01 - Current Royal Society of Chemistry MRSC member

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022/03/01 - 2023/08/31 Biorefineries and Bioprocesses. Biorefineries and Bioprocesses (Licenciatura) Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/11/29 - 2023/08/31 Enzymatic Engineering Engenharia Enzimática (Licenciatura) Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/03/01 - 2021/06/30 Biochemical Engineering Biotecnologia (Engenharia Bioquímica) (Mestrado) Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/09/01 - 2019/12/31 Biological Engineering Laboratory II Integrated Master Degree in Biological Engineering (Mestrado integrado) Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/01/01 - 2017/06/30 Green Technologies and Strategic Management Integrated Master Degree in Biological Engineering and in Chemical Engineering (Mestrado integrado) Universidade de Lisboa Instituto Superior Técnico, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2022/09/01 - Current Journal of Food Composition and Analysis Elsevier
2022/04/01 - Current Nanomaterials MDPI
2022/03/01 - Current Molecules MDPI
2022/01/10 - Current Frontiers in Chemistry Frontiers
2021/09/24 - Current Separations MDPI
2020/12/01 - Current Toxins MDPI
2020/11/01 - Current Microchemical Journal Elsevier
2020/07/08 - Current ACS Biomaterials Science and Engineering ACS Publications
2017/02/26 - Current Journal of Chromatography A (0021-9673) Elsevier
2015/05/01 - Current Industrial and Engineering Chemistry Research ACS Publications

Mentoring / Tutoring

Topic Student name
2022/09/05 - Current HPLC for validation of sample treatment Cristiana Domingues
2020/03/09 - 2020/05/29 Biomimetic adsorbers for purification in pharma industry - OSN membranes with DNA bases Inês Carvalho
2020/03/09 - 2020/05/29 Biomimetic adsorbers for purification in pharma industry - molecular imprinted polymers Filipa Carmona
2019/11/02 - 2020/02/10 Benchmarking of a portable biosensing platform for plant health through high performance liquid chromatography Eduardo J. S. Brás

Other jury / evaluation

Activity description Institution / Organization
2022/11/24 - Current Main evaluator of a 2nd Cycle Integrated Project in Biomedical Engineering Universidade de Lisboa Instituto Superior Técnico, Portugal
Distinctions

Other distinction

2017 Individual Post-doc grant
Fundação para a Ciência e a Tecnologia, Portugal
2010 TERACHEM 2010 conference bursary
Society of Radiopharmaceutical Sciences, United States
2009 Harry S. Truman Memorial Veterans' Hospital visiting scholar bursary
Missouri Foundation for Medical Research, United States
2006 Individual PhD Scholarship
Fundação para a Ciência e a Tecnologia, Portugal
2004 Final year internship grant
Programa Operacional de Desenvolvimento Educativo para Portugal (PRODEP), Portugal