João Basso graduated in Pharmaceutical Sciences at the University of Coimbra in 2017, receiving the "3% Best Students Award"
in the academic years of 2014/2015 and 2015/2016. JB began his professional activity as a Master's Fellow in the FCT Project
"Dual nanostructured lipid carriers (NLCs) as a multifunctional platform for brain tumor therapy" (PTDC/MHC-CED/2658/2014).
In 2019, he secured a competitive PhD scholarship from FCT (ranked 2nd out of 120 applicants in the "Materials Engineering
and Nanotechnology" panel) to develop lipid carriers for drug and gene delivery in glioblastoma. Other research interests
include the topical and intravenous administration of targeted drug delivery therapies, biomaterials, and nanomedicine pharmacokinetics.
JB has acquired experience in developing novel carrier systems using systematic and risk-based approaches, incorporating Quality
by Design principles, machine learning algorithms, and computational modeling. His technical expertise includes nanoparticle
formulation and characterization (DLS, DSC, ATR-FTIR, XRPD, analytical centrifugation, drug release kinetics), and he has
developed several chromatographic methods for analytical and bioanalytical quantification. He is also skilled in cell culture
(monolayer, transwell, and 3D cancer models, gene material transfection, RT-PCR, and internalization studies with fluorescence
microscopy), proteomics, and in vivo studies (drug and nanomedicine administration, development of orthotopic xenograft brain
cancer models, anticancer efficacy studies with MRI data and survival analyses). During his PhD studies, JB has participated
in other research projects related to nanotechnology, including NANOLIP (01/SAICT/2021-SAICT-181224) and (NANOPEP 10.54499/2022.06174).
JB is a member of the Global Burden of Disease (GBD) Collaborator Network, holds one International Patent for a nanomedicine
and is an Invited Reviewer for several Q1 journals specialized in oncology drug delivery, nanotechnology, and pharmaceutics.
He is a recipient of the "Professor Doutor António Lima de Faria" Scholarship for Scientific Innovation. JB is also actively
involved in several outreach activities for the promotion of science, including the organization of the Pint of Science (Coimbra)
festival, as collaborator and coordinator, technical visits to the Pharmaceutical Technology Laboratories of the Faculty of
Pharmacy of the University of Coimbra, and the participation in the European Researcher's Night 22/23.
PhD outputs: 5 articles in specialized peer-reviewed journals, 4 book chapters, 5 oral communications (3 international), 11
poster presentations (1 award for best oral communication, 2 awards for best poster presentation). 1 publication highlighted
by the editorial team due to the "particular interest to readers/importance to the research field". 1 publication featured
on the journal cover.
Overall metrics: 14 publications in peer-reviewed journals, 7 book chapters (> 375 citations, h-index=11, i10-index=11), 18
oral presentations, 20 poster presentations, 2 publications featured on journal covers. 7 publications in The Lancet and The
Lancet Neurology via the GBD Consortium (> 1800 citations, h-index=14, i10-index=17).