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I graduated in Pharmacy in 2015 from the High School of Health, Polytechnic of Porto and two years later I earned my MSc degree in Pharmaceutical Chemistry (2017) from the Faculty of Pharmacy, University of Porto (FFUP) titled "Development of a Proliposome Formulation as a Drug Carrier for a Novel Antitumor Drug". My interest in science began during my master's degree, it immediately became clear that this was an area I wanted to pursue. In 2019, I had a 6 moths fellowship under the project “Design of Fluorinated Ionic Liquids as novel task-specific fluids” (PTDC/QEQ-EPR/5841/2014), founded by FCT, at the Faculty of Science and Technology, University of Lisbon, Portugal. In 2019, I was granted by FCT with a PhD grant (SFRH/BD/144607/2019) and five years later I successfully concluded my PhD in Pharmaceutical Sciences with a specialization in Pharmaceutical Technology, at the Faculty of Pharmacy, University of Porto (FFUP), titled "Synthesis, preparation, and characterization of polymersome systems loaded with anti-glioblastoma small Molecules”. During my PhD, I went on an international experience at the Institute of Bioengineering of Catalonia, Barcelona, where I gained expertise in functionalization and characterization of PMs by working for 6 months in Professor Giuseppe Battaglia group. Since my PhD, I have been working as a Junior Researcher at UCIBIO-FFUP-MedTech, and I was nominated as the communication ambassador of UCIBIO-FFUP-MedTech. I have been supervising the experimental work of undergraduate students as well as master’s students. In the last 5 years, the results of my research work have been disseminated through 12 posters, 4 oral communications, and 8 original articles. My original research work was honored by 1 award for best poster communication obtained at the 17th Young Research Meeting of the University of Porto, IJUP, 2024 (co-author), and two honorable paper selections for the cover of 2 international journals, Molecules (author) and Pharmaceuticals (co-author).
Identification

Personal identification

Full name
Ana Daniela Coutinho Alves

Citation names

  • Ana Alves
  • Alves, A.

Author identifiers

Ciência ID
2F1C-5703-7C2F
ORCID iD
0000-0002-8746-4291

Email addresses

  • adcoutinhoalves@gmail.com (Professional)
  • anadaniela92@hotmail.com (Personal)

Telephones

Mobile phone
  • 914143962 (Personal)

Addresses

  • Rua D.Dinis lote 40 edifício Património 1ºesquerdo , 4610-162, Felgueiras, Porto, Portugal (Personal)

Websites

Knowledge fields

  • Engineering and Technology - Nano-technology - Nano-materials
  • Exact Sciences - Chemical Sciences - Polymer Science
  • Exact Sciences - Chemical Sciences - Analytical Chemistry
  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2019/11/01 - 2024/05/29
Concluded
Ph.D. in Pharmaceutical Sciences (Doutoramento)
Major in Pharmaceutical Technology
Universidade do Porto Faculdade de Farmácia, Portugal
"Synthesis, preparation and characterization of polymersome systems loaded with anti-glioblastoma small molecules" (THESIS/DISSERTATION)
2015/09/14 - 2017/09/29
Concluded
Pharmaceutical Chemistry (Mestrado)
Major in Pharmaceutical Technology
Universidade do Porto Faculdade de Farmácia, Portugal
"Development of a Proliposome Formulation as a Drug Carrier for a Novel Antitumor Drug" (THESIS/DISSERTATION)
2011/09/18 - 2015/07/31
Concluded
Pharmacy (Licenciatura)
Major in Pharmacy
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
"Development of new drugs Topoisomerase II synthesis and inhibition in cancer" (THESIS/DISSERTATION)
Affiliation

Science

Category
Host institution
Employer
2024/10/01 - Current Researcher (Research) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2022/06 - 2022/12 Visiting Researcher (Research) Institut de Bioenginyeria de Catalunya, Spain
Institut de Bioenginyeria de Catalunya, Spain
2019/05 - 2019/11 Researcher (Research) Universidade Nova de Lisboa, Portugal
Universidade Nova de Lisboa, Portugal
2015/01/05 - 2015/04/10 Research Trainee (Research) Laboratório de pesquisa da Universidade de Bolonha, Italy
Laboratório de pesquisa da Universidade de Bolonha, Italy

Positions / Appointments

Category
Host institution
Employer
2025/01/01 - Current Communication Ambassador Unidade de Ciências Biomoleculares Aplicadas, Portugal
Universidade do Porto, Portugal

Others

Category
Host institution
Employer
2018/07/02 - 2019/04/10 Laboratório de manipulação Laboratório de manipulação da Farmácia Gaia Jardim, Portugal
2017/11/01 - 2018/07/01 Laboratório de manipulação Laboratório de manipulação da Farmácia Barreiros, Portugal
2016/04/15 - 2017/01/15 Estágio profissional em Farmácia comunitária Farmácia Areosa , Portugal
Farmácia Areosa , Portugal
2015/05/04 - 2015/05/29 Estágio curricular em Farmácia hospitalar Hospital de S. João, Portugal
Hospital de S. João, Portugal
2014/09/15 - 2014/12/19 Estágio curricular em Farmácia comunitária Farmácia Areosa , Portugal
Farmácia Areosa , Portugal
Projects

Grant

Designation Funders
2019/11/01 - 2024/05/29 Synthesis, preparation and characterization of polymersome systems loaded with anti-glioblastoma small molecules
SFRH/BD/144607/2019
PhD Student Fellow
Universidade do Porto Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2019/05/01 - 2019/10/31 Development of Fluorinated Ionic Liquids as Solvents for Drug Delivery
NOVA.ID.FCT, FCT (PTDC/QEQ-EPR/5841/2014), financed by national funds through the FCT/MCTES (PIDDAC)
Research Fellow
Universidade Nova de Lisboa Departamento de Química, Portugal
Associação para a Inovação e Desenvolvimento da FCT
Ongoing
Outputs

Publications

Journal article
  1. Sias-Fonseca, Letícia; Costa, Paulo C.; Saraiva, Lucília; Alves, Ana; Amaral, Maria Helena. "Promising Nanotechnology-Based Strategies for Melanoma Treatment". Colloids and Interfaces 9 4 (2025): 53. https://doi.org/10.3390/colloids9040053.
    10.3390/colloids9040053
  2. Saraiva, Nuno M.; Alves, Ana; Barbosa, Ana Isabel; Marinho, Andreia; Reis, Salette; Correia-da-Silva, Marta; Costa, Paulo C.. "Click on Click: Click-Flavone Glycosides Encapsulated in Click-Functionalised Polymersomes for Glioblastoma Therapy". Pharmaceutics 17 6 (2025): 771. https://doi.org/10.3390/pharmaceutics17060771.
    10.3390/pharmaceutics17060771
  3. Alves, Ana; Pfeifer, Peter; Marinho, Andreia; Nunes, Cláudia; Reis, Salette; Ferreira, Domingos; Correia-da-Silva, Marta; et al. "Sometimes less is more: Avidity-dependent transport of targeted polymersomes across the blood-brain-barrier". RSC Pharmaceutics (2025): https://doi.org/10.1039/d4pm00338a.
    Published • 10.1039/d4pm00338a
  4. Saraiva, Nuno M.; Alves, Ana; Costa, Paulo C.; Correia-da-Silva, Marta. "Click Chemistry in Polymersome Technology". Pharmaceuticals 17 6 (2024): 747. http://dx.doi.org/10.3390/ph17060747.
    10.3390/ph17060747
  5. Alves, Ana; Silva, Ana Margarida; Nunes, Claúdia; Cravo, Sara; Reis, Salette; Pinto, Madalena; Sousa, Emília; et al. "The Synthesis and Characterization of a Delivery System Based on Polymersomes and a Xanthone with Inhibitory Activity in Glioblastoma". Life 14 1 (2024): 132. http://dx.doi.org/10.3390/life14010132.
    Published • 10.3390/life14010132
  6. Alves, Ana; Silva, Ana M.; Moreira, Joana; Nunes, Claúdia; Reis, Salette; Pinto, Madalena; Cidade, Honorina; et al. "Polymersomes for Sustained Delivery of a Chalcone Derivative Targeting Glioblastoma Cells". Brain Sciences 14 1 (2024): 82. http://dx.doi.org/10.3390/brainsci14010082.
    Published • 10.3390/brainsci14010082
  7. Alves, Ana; Costa, Paulo; Pinto, Madalena; Ferreira, Domingos; Correia-da-Silva, Marta. "Small Molecules of Marine Origin as Potential Anti-Glioma Agents". Molecules 26 9 (2021): 2707. http://dx.doi.org/10.3390/molecules26092707.
    Published • 10.3390/molecules26092707
  8. Alves, Ana; Correia-da-Silva, Marta; Nunes, Claúdia; Campos, João; Sousa, Emília; Silva, Patrícia; Bousbaa, Hassan; et al. "Discovery of a New Xanthone against Glioma: Synthesis and Development of (Pro)liposome Formulations". Molecules 24 3 (2019): 409. http://dx.doi.org/10.3390/molecules24030409.
    10.3390/molecules24030409
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/04/28 Synthesis, preparation and characterization of polymersome systems loaded with anti-glioblastoma small molecules. Portuguese Young Chemists Meeting,
(Faro, Portugal)
2024/11/28 Synthesis, preparation and characterization of polymersome system loaded with anti-glioblastoma small molecules New Drug Delivery Systems
Faculty of Pharmacy University of Porto (Porto, Portugal)
2024/11/13 Click on click: Unlocking the potential of click chemistry in drug delivery and small molecules XXVIII Encontro Luso-Galego de Química
(Vigo, Spain)
2024/07/03 Click on click: Development of functionalised nanoparticles for drug delivery of small molecules Encontro Ciência 2024
(Porto, Portugal)
2024/05/08 Click on click: Development of functionalized polymersomes encapsulating promising anti-cancer small molecules Investigação Jovem da Universidade do Porto
(Porto, Portugal)
2023/11/22 Functionalization and Characterization of Hyaluronic Acid with Polymersomes for Glioblastoma. XXVII Encontro Luso-Galego de Química
(Porto, Portugal)
2023/10/26 Synthesis, Functionalization and Characterization of Polymersomes for the Treatment of Glioblastoma. Congresso Iberoamericano de Ciências Farmacêuticas
COIFFA (Portugal)
2023/07/24 Polymersomes targeting glioblastoma cells for chalcone delivery XXVIII Encontro Nacional da SPQ
(Aveiro, Portugal)
2023/05/11 Polymersomes as a new vector for the treatment of glioblastoma 29th Porto Cancer Meeting
(Porto, Portugal)
2022/10/24 Synergic approach to the treatment of glioblastoma through a novel xanthone-polymersome system. 15th IBEC Symposium
(Catalonia, Spain)
2022/04/20 Synthesis, and characterization of polymersomes with a glycosylated xanthone for glioma. 14th National Organic Chemistry Meeting and 7th National Medicinal Chemistry Meeting
(Lisboa, Portugal)
2022/01/24 Synthesis, and characterization of a promising polymersome with a chalcone derivative for glioma. 1st Advances in Polymeric Micelles for Therapeutic Applications
(Coimbra, Portugal)
2021/11/26 Drug delivery system based on polymersomes for a new compound with potential application in glioblastoma treatment. IX Congreso Iberoamericano de Ciências Farmacêuticas em Líne 2021 - COIFFA
(Guatemala)
2021/05/20 Development of a dual target delivery system based on polymersomes and a glycosylated xanthone with inhibitory activity in glioma. 27th Porto Cancer Meeting
(Porto, Portugal)
2019/05/17 Discovery of a new xanthone against glioma: synthesis and development of (pro)liposome formulations. 4th Meeting of Medicinal Biotechnology
(Porto, Portugal)
2017/02/08 Development of an HPLC method for the quantification of a new glycosylated xanthone with cell growth inhibitory activity. IJUP'17 – 10th Meeting of Young Researchers of University of Porto
(Porto, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2024/09/01 - Current Innovative Drug Delivery Systems for the Treatment of Glioblastoma
Supervisor
Pharmaceutical Technology (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2024/09/01 - Current Innovative Drug Delivery Systems for the Topical Treatment of Psoriasis
Supervisor
Pharmaceutical Technology (Master)
Universidade do Porto Faculdade de Farmácia, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2025/10/22 - 2025/10/22 BioSeminar chair
Conference
BioSeminar UCIBIO
Universidade do Porto Faculdade de Farmácia, Portugal
2022/10/19 - 2022/10/19 European Training Network: Theracat
Conference
European Training Network: Theracat
Institut de Bioenginyeria de Catalunya, Spain
2022/07/15 - 2022/07/15 Novel Nuclear Magnetic Resonance (NMR) applications in the clinical field and Versatile gelatine-based biomaterials compatible with neuronal differentiation
Conference
Novel Nuclear Magnetic Resonance (NMR) applications in the clinical field and Versatile gelatine-based biomaterials compatible with neuronal differentiation
Institut de Bioenginyeria de Catalunya, Spain
2022/06/06 - 2022/06/06 Safety and hygiene at work
Conference
Safety and hygiene at work
Universidade do Porto Faculdade de Farmácia, Portugal
2021/11/04 - 2021/11/04 Synthesis Methods and N,N-Disubstituted Thiomide Derivatives and Their Characterization by Spectroscopic Techniques (IR, NMR and Mass)
Conference
Synthesis Methods and N,N-Disubstituted Thiomide Derivatives and Their Characterization by Spectroscopic Techniques (IR, NMR and Mass)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/03/04 - 2021/03/04 Ocean Planning in the Age of Climate Change, Sciaena’s coordination
Conference
Ocean Planning in the Age of Climate Change, Sciaena’s coordination
2021/02/24 - 2021/02/24 An overview of super resolution microscopy: 1 part, Andor Technology
Conference
An overview of super resolution microscopy: 1 part, Andor Technology
2021/02/18 - 2021/02/19 4th International Conference on biological and Biomimetic Adhesives
Conference
4th International Conference on biological and Biomimetic Adhesives
Universidade de Aveiro, Portugal
2020/02/18 - 2020/02/18 Web of Science e Scopus
Conference
Web of Science e Scopus
Universidade do Porto Faculdade de Farmácia, Portugal
2020/02/11 - 2020/02/11 PubMed: search by word and subject, limiting results, obtaining the full text of articles
Conference
PubMed: search by word and subject, limiting results, obtaining the full text of articles
Universidade do Porto Faculdade de Farmácia, Portugal
2020/01/08 - 2020/01/08 Introduction to EndeNote X9: from creating a library to writing a document
Conference
Introduction to EndeNote X9: from creating a library to writing a document
Universidade do Porto Faculdade de Farmácia, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2025/09/23 Cosmetic Properties of Garcinia Species
(Thesis) Main arguer
Husam N Burhanuldeen (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2025/09/04 Gilteritinib no tratamento da Leucemia Mieloide Aguda (LMA) Recidivante ou Refratáriacom uma Mutação FLT3 : uma Scoping Review
(Thesis) Arguer
Igor Abel Branco Pereira (Other)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2025/07/18 Nanoparticle-Based Strategies for the Treatment of Neurodegenerative Diseases
(Thesis) Main arguer
Maria João de Araújo Machado (Master)
Universidade do Porto Faculdade de Farmácia, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2024/11/12 - 2024/11/12 Biotechnology, and Advanced Pharmaceutical Technology: Preparation of Injectables Pharmaceutical Sciences (Mestrado integrado) Universidade do Porto Faculdade de Farmácia, Portugal
2024/10/26 - 2024/10/26 Semisolid Systems: Skin Biometrics Pharmaceutical Technology (Mestrado) Universidade do Porto Faculdade de Farmácia, Portugal
2024/09/28 - 2024/09/28 Semisolid Systems: Validation of Analytical Methods, Pharmaceutical Technology (Mestrado) Universidade do Porto Faculdade de Farmácia, Portugal

Mentoring / Tutoring

Topic Student name
2025/06/01 - 2025/07/31 Encapsulation of Rutin in Lipid Nanoparticles for Glioblastoma Theodoros Vogiatzis
2025/05/30 - 2025/07/31 Rutin incorporated into lipid nanoparticles for the treatment of glioblastoma Theodoros Vogiatzis
2025/04/14 - 2025/04/30 Formulation and physicochemical characterization of nanostructured lipid carriers loaded with ibuprofen Mihail Aleksandrov
2025/01/01 - 2025/04/01 Development of Nanolipid Carriers with Valproic acid Robert-Alexandru VLAD
2024/10/01 - 2024/12/31 Lipid Nanoparticles Loaded with Dithranol: Optimizing Formulations for Psoriasis Ylenia Russo

Other jury / evaluation

Activity description Institution / Organization
2020/12/10 - 2020/12/17 Evaluator - Scientific Pedagogical Journeys (Madalena Pinto 2020) Universidade do Porto Faculdade de Farmácia, Portugal
Distinctions

Award

2024 17th Young Research Meeting
2019 Individual PhD Fellowship
2019 Individual Master Fellowship