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Teresa Raquel Tremoço Dias de Abreu. Completed the Mestrado integrado in Integrated master's degree (BSc and MSc) in Pharmaceutical Sciences in 2018/09/13 by University of Coimbra, Faculty of Pharmacy . Attends the Doutoramento in Doctoral Programme in Pharmaceutical Sciences - Major in Pharmaceutical Technology by University of Coimbra, Faculty of Pharmacy since 2021. Is PhD Student in iMed.ULisboa . Published 2 articles in journals. Has 2 section(s) of books. Organized 1 event(s). Participated in 3 event(s). Has received 6 awards and/or honors. Participates and/or participated as Research Fellow in 3 project(s) and Researcher in 1 project(s). Works in the area(s) of Medical and Health Sciences with emphasis on Anticancer Immunotherapy. In her professional activities interacted with 37 collaborator(s) co-authorship of scientific papers. In her curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: CAR-T cells; solid tumors; in vitro testing
Identification

Personal identification

Full name
Teresa Raquel Tremoço Dias de Abreu
Date of birth
1995/03/27
Gender
Female

Citation names

  • Abreu, Teresa

Author identifiers

Ciência ID
2E18-0BF5-6D94
ORCID iD
0000-0002-7462-3257

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Advanced (C1) Upper intermediate (B2) Upper intermediate (B2) Intermediate (B1)
Education
Degree Classification
2021 - 2025
Ongoing
Doctoral Programme in Pharmaceutical Sciences - Major in Pharmaceutical Technology (Doutoramento)
University of Coimbra, Faculty of Pharmacy , Portugal
2020/09 - 2021/01/07
Concluded
Advanced Course in Academic English I (Outros)
Faculty of Letters, University of Coimbra, Portugal
17
2013/09/13 - 2018/09/13
Concluded
Integrated master's degree (BSc and MSc) in Pharmaceutical Sciences (Mestrado integrado)
University of Coimbra, Faculty of Pharmacy , Portugal
"CAR-T cells as an anticancer therapy: current challenges and emerging opportunities" (THESIS/DISSERTATION)
17
2007 - 2015
Concluded
Violin Course, 7th Grade (7/8) (Outros)
Music Conservatory of Coimbra (CMC), Portugal
14
2005 - 2011
Concluded
Cambridge ESOL level 1: First Certificate in English B2 (Outros)
British Council, Portugal
B
Affiliation

Science

Category
Host institution
Employer
2018/12 - 2021/02 Researcher (Research) Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal
2016/11 - 2017/05 Research Trainee (Research) Molecular Biology and Cell Culture Laboratory, FFUC, Portugal
University of Coimbra, Faculty of Pharmacy , Portugal

Teaching in Higher Education

Category
Host institution
Employer
2020/02/19 - 2020/08/31 Invited Assistant (University Teacher) University of Coimbra, Faculty of Pharmacy , Portugal
University of Coimbra, Faculty of Pharmacy , Portugal

Others

Category
Host institution
Employer
2021/03 - Current PhD Student iMed.ULisboa , Portugal
Faculty of Pharmacy, University of Lisbon, Portugal
2023/02 - 2023/09 Visiting PhD Student (Pathology Department) Leids Universitair Medisch Centrum, Netherlands
Universiteit Leiden, Netherlands
2020/04 - 2020/05 Volunteer at COVID-19 UC Lab University of Coimbra, Portugal
Center for Neuroscience and Cell Biology (CNC), Portugal
2018/05 - 2018/08 Curricular Traineeship Program Autoridade Nacional do Medicamento e Produtos de Saúde, I.P, Portugal
University of Coimbra, Faculty of Pharmacy , Portugal
2018/01 - 2018/04 Curricular Traineeship Program Farmácia São José Unipessoal Lda, Portugal
University of Coimbra, Faculty of Pharmacy , Portugal
2017/07/01 - 2017/07/31 Summer Internship (Quality Control Department) Bluepharma, Portugal
University of Coimbra, Portugal
2016/09 - 2016/11 Extracurricular Internship Program Clinical Analysis Laboratory, FFUC, Portugal
University of Coimbra, Faculty of Pharmacy , Portugal
2016/07/01 - 2016/07/31 Summer Internship Farmácia São José Unipessoal Lda, Portugal
University of Coimbra, Portugal
2015/10 - 2016/05 Extracurricular Internship Program Observatory of Herb-Drug Interactions (OIPM), FFUC, Portugal
University of Coimbra, Faculty of Pharmacy , Portugal
Projects

Grant

Designation Funders
2022/01 - 2023/12 EXPL/MED-FAR/1512/2021_nuCAR/Anti-PDL1
EXPL/MED-FAR/1512/2021
Researcher
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2020/04/01 - 2021/06/30 HEALTHYAGING 2020 (BIM 7.1.4)
HEALTHYAGING 2020 (BIM 7.1.4)
Research Fellow
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2020/05/11 - 2021/03/31 BIM-PAC CANCEL_STEM/2020/04
BIM-PAC CANCEL_STEM/2020/04
Research Fellow
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal
Concluded
2018/12/16 - 2020/02/09 HEALTHYAGING 2020 (BIM 7.1.2)
Research Fellow
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal
University of Coimbra
Concluded
Outputs

Publications

Book chapter
  1. Abreu, Teresa; Biscaia, Mariana; Gonçalves, N.; Fonseca, Nuno A.; Moreira, João Nuno. "In vitro and in vivo tumor models for the evaluation of anticancer nanoparticles". In Biomedicine for Cancer Therapy, edited by Hélder Santos; Flavia Fontana. Springer Nature, 2020.
    Published
  2. Ribeiro, Rita; Abreu, Teresa; Silva, Ana Catarina; Gonçalves, João; Moreira, João Nuno. "Insights on the Formulation of Recombinant Proteins". In Current Applications of Pharmaceutical Biotechnology, 23-54. Springer International Publishing, 2019.
    Published • 10.1007/10_2019_119
Conference abstract
  1. Abreu, Teresa; Godinho-Santos, A; Moreira, JN; Gonçalves, J. "P06.02 Anti-nucleolin CAR (chimeric antigen receptor)-T cell targeting triple-negative breast cancer - critical parameters in CAR-T cells generation". Paper presented in 9th Immunotherapy of Cancer Conference, Munique, 2022.
    Published • 10.1136/jitc-2022-itoc9.42
Conference poster
  1. Abreu, Teresa; Godinho-Santos A.; Moreira J.N; Gonçalves J.. "Poster nº 24: Nucleolin as a CAR-T cell target for solid tumors - brief notions into anti-nucleolin CAR-T cells manufacturing and in vitro testing". Paper presented in III ASPIC-ASEICA International Meeting – Cancer Immunology, Tumor Microenvironment and Metastasis, 2023.
  2. Abreu, Teresa; Godinho-Santos A.; Moreira J.N; Gonçalves J. "First steps on producing and testing anti-nucleolin CAR-T cells in vitro". Paper presented in Scientific Symposium "O Futuro Hoje: Novas Terapêuticas Moleculares e Biológicas", 2023.
  3. Abreu, Teresa; Godinho-Santos A.; Moreira J.N; Gonçalves J.. "Anti-nucleolin CAR (chimeric antigen receptor)-T cells against Triple-Negative Breast Cancer - optimizing CAR-T cells production". Paper presented in ESGCT 29th Congress in collaboration with BSGCT, 2022.
  4. Abreu, Teresa; Fonseca, Nuno A.; Moreira, João Nuno. "The role of N-glycosylation on the specific binding of the tumor homing F3 peptide to nucleolin". Paper presented in BEBday 2019, 2019.
  5. Abreu, Teresa; Lopes, Rui; Fonseca, Nuno A.; Moreira, João Nuno. "Specific recognition of the onco-target nucleolin by the tumor homing F3 peptide". Paper presented in 1st Annual Meeting in Pharmaceutical Sciences, 2019.
  6. Abreu, Teresa; Moreira, João Nuno. "CAR-T cells as an Anticancer Therapy: current challenges and emerging opportunities". Paper presented in IPAP18 - Innovation in Pharmacy: Advances and Perspectives, 2018.
Journal article
  1. Fonseca, Nuno A.; Gregório, Ana C.; Mendes, Vera M.; Lopes, Rui; Abreu, Teresa; Gonçalves, Nélio; Manadas, Bruno; et al. "GMP-grade nanoparticle targeted to nucleolin downregulates tumor molecular signature, blocking growth and invasion, at low systemic exposure". Nano Today 37 (2021): 101095. http://dx.doi.org/10.1016/j.nantod.2021.101095.
    10.1016/j.nantod.2021.101095
  2. Abreu, Teresa R.; Fonseca, Nuno A.; Gonçalves, Nélio; Moreira, João Nuno. "Current challenges and emerging opportunities of CAR-T cell therapies". Journal of Controlled Release 319 (2020): 246-261. http://dx.doi.org/10.1016/j.jconrel.2019.12.047.
    10.1016/j.jconrel.2019.12.047
Thesis / Dissertation
  1. Abreu, Teresa. "CAR-T cells as an anticancer therapy: current challenges and emerging opportunities". Master, Universidade de Coimbra Faculdade de Farmácia, 2018. http://hdl.handle.net/10316/84667.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/03/04 "Potential and limitations of CAR-T cell therapies" (Academic Lecture) Master's Degree in Pharmaceutical Biotechnology
Faculty of Pharmacy, University of Coimbra (Coimbra, Portugal)
2023/01/24 "Generating CAR-T cells - brief comparison between research and clinical settings" (Laboratorial Course) Laboratorial Course in Advanced Therapy Medicinal Products (ATMPs)
Research Institute for Medicines ( imed.ULisboa ), Faculty of Pharmacy, University of Lisbon (Lisbon, Portugal)
2022/05/11 "Basic steps on CAR-T cells generation" (Academic Lecture) Master's Degree in Biopharmaceutical Sciences
Faculty of Pharmacy, University of Lisbon (Lisbon, Portugal)
2022/04/30 "CAR-T cell therapies: from the bench to the clinic" (Invited Oral Communication) 30ª Sabatina de Hematologia , Fórum Hematológico
University Hospital of Coimbra (CHUC) (Coimbra, Portugal)
2022/02/19 "CAR-T cell therapies - a brief introduction to their potential and limitations" (Academic Lecture) Master's Degree in Pharmaceutical Biotechnology
Faculty of Pharmacy, University of Coimbra (Coimbra, Portugal)
2021/11/23 "CAR-T cell therapies in solid tumors - limitations, clinical overview and monitoring" (Invited Oral Communication) Advanced Course entitled Novos avanços da citometria de fluxo nas neoplasias sólidas
University Hospital of Coimbra (CHUC) (Coimbra , Portugal)
2021/01/13 "Current challenges and emerging opportunities of CAR-T cells" (Academic Lecture) Master's Degree in Pharmaceutical Biotechnology
Faculty of Pharmacy, University of Coimbra (Coimbra, Portugal)

Event organisation

Event name
Type of event (Role)
Institution / Organization
2019/09/27 - 2019/09/27 European Researchers' Night 2019 (2019/09/27 - 2019/09/27)
Other (Member of the Organising Committee)
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2021/10/12 - 2021/10/14 Representing researcher of the "Tumor microenvironment and targeted therapies" lab from the Center of Neuroscinece and Cell Biology of the University of Coimbra (CNC)
Festival
International Festival of Science (FICA)
Camara Municipal Oeiras, Portugal
2019/10/04 - 2019/10/04 Workshop session on how to write successful scientific papers
Workshop
How to get Published
Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal
2018/04/19 - 2018/04/20 Summit on World Health concerns and future outcomes (Participant)
Congress
World Health Summit Regional Meeting 2018
WHS Foundation GmbH c/o Charité – Universitätsmedizin Berlin, Germany
Distinctions

Award

2023 EACR Travel Fellowship
European Association For Cancer Research, United Kingdom
2023 Best Poster of the Scientific Symposium "O Futuro Hoje: Novas Terapêuticas Moleculares e Biológicas"
Ordem dos Farmaceuticos, Portugal
2018 The 3% Best UC Students Award
University of Coimbra, Faculty of Pharmacy , Portugal
2017 The 3% Best UC Students Award
University of Coimbra, Faculty of Pharmacy , Portugal
2016 The 3% Best UC Students Award
University of Coimbra, Faculty of Pharmacy , Portugal
2015 The 3% Best UC Students Award
University of Coimbra, Faculty of Pharmacy , Portugal