Identification
Personal identification
- Full name
- Ana Rita Cabral Martins Carlos
Citation names
- Carlos, Ana Rita
Author identifiers
- Ciência ID
- 2E10-CE9E-ECE4
- ORCID iD
- 0000-0002-6953-1163
- Researcher Id
- K-6014-2019
Email addresses
- arcarlos@ciencias.ulisboa.pt (Professional)
Telephones
- Telephone
-
- 217500000 Ext.: 522347 (Professional)
Addresses
- Departamento de Biologia Animal Faculdade de Ciências, Universidade de Lisboa, Campo Grande , 1749-016 , Lisboa, Lisboa, Portugal (Professional)
Websites
- www.linkedin.com/in/ana-rita-carlos-68445942 (Social media)
- https://scholar.google.pt/citations?user=dhD0TKMAAAAJ&hl=en (Scholar)
- https://ce3c.ciencias.ulisboa.pt/member/anaritacarlos (Professional)
- https://www.scopus.com/authid/detail.uri?authorId=35236375300 (Scholar)
Knowledge fields
- Medical and Health Sciences - Basic Medicine - Pathology
- Medical and Health Sciences - Basic Medicine - Physiology
- Natural sciences - Biological Sciences - Cell Biology
- Medical and Health Sciences - Basic Medicine - Physiology
- Medical and Health Sciences - Basic Medicine - Pathology
- Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
- Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
- Medical and Health Sciences - Basic Medicine - Immunology
- Medical and Health Sciences - Health Sciences - Infectious Diseases
- Natural sciences - Biological Sciences - Molecular Biology
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
Portuguese (Mother tongue) | |||||
English | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) |
Spanish; Castilian | Proficiency (C2) | Proficiency (C2) | Advanced (C1) | Proficiency (C2) |
Education
Degree | Classification | |
---|---|---|
2009/01/01 - 2013/01/18
Concluded
|
DPhil in Radiobiology (Doctor of Philosophy)
University of Oxford, United Kingdom
"DNA damage responses to loss of telomere integrity" (THESIS/DISSERTATION)
|
N/A |
2008/11/08
Concluded
|
Mestrado em Biologia Molecular e Genética (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Análise da expressão génica em estirpes de Enterococcus como resposta a diferentes condições ambientais" (THESIS/DISSERTATION)
|
19 |
2007
Concluded
|
Biologia Microbiana e Genética (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"(Não aplicável)" (THESIS/DISSERTATION)
|
17 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2022/11/14 - Current | Principal Investigator (Research) | Universidade de Lisboa Faculdade de Ciências, Portugal |
2019/06/01 - 2022/11/13 | Auxiliary Researcher (Research) | Universidade de Lisboa Faculdade de Ciências, Portugal |
Centro de Ecologia Evolução e Alterações Ambientais, Portugal | ||
2013/03/01 - 2019/05/31 | Postdoc (Research) | Fundação Calouste Gulbenkian, Portugal |
Instituto Gulbenkian de Ciência, Portugal |
Teaching in Higher Education
Category Host institution |
Employer | |
---|---|---|
2022/11/14 - Current | Assistant Professor (University Teacher) | Universidade de Lisboa Faculdade de Ciências, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2022/03/01 - Current | Extracellular matrix in health and disease
CE3C#1036
Researcher
FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal
Centro de Ecologia Evolução e Alterações Ambientais, Portugal |
Ongoing
|
2022/01/15 - Current | Overcoming the challenges of recombinant adenoassociated virus production to treat Muscular dystrophy
PTDC/BTM-ORG/1383/2020
Researcher
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
|
Fundação para a Ciência e a Tecnologia |
2020/09/11 - 2023/09/10 | Understanding the responses of fetal muscle stem cells and myoblasts to their niche in a mouse model for LAMA2-CMD
23049
Researcher
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
|
AFM-Téléthon
Ongoing
|
2020/03/01 - 2022/12/31 | Role of senescence on the onset of muscle dystrophy
0846-Prémio L'Oreal
Principal investigator
Centro de Ecologia Evolução e Alterações Ambientais, Portugal
|
L'Oréal Portugal, Unipessoal, Lda
Ongoing
|
2018/06/01 - 2019/05/31 | Metabolic adaptation to infectious diseases
LISBOA-01-145-FEDER-029411
Post-doc Fellow
|
Fundação para a Ciência e a Tecnologia |
2013/06 - 2016/05 | TREAT LIVER DISEASES BY TARGETING HEPATOCYTE NECROPTOSIS | Fundação para a Ciência e a Tecnologia |
Contract
Designation | Funders | |
---|---|---|
2025/01/01 - 2026/06/30 | Targeting LAMA2-MD with CRISPR-Cas9 based gene therapy
2023.11177.PEX
Principal investigator
FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal
Goldsmiths University of London, United Kingdom Sorbonne Université, France |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2025/01/01 - 2026/06/30 | A novel role for LAMA2, an extracellular matrix component, in melanoma progression
2023.15036.PEX
Co-Principal Investigator (Co-PI)
FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal
Goldsmiths University of London, United Kingdom Fundação Champalimaud, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2021/01/01 - 2025/12/31 | CHANGE - Instituto para as Alterações Globais e Sustentabilidade
LA/P/0121/2020
Universidade do Algarve, Portugal
Fundação Gaspar Frutuoso, Portugal FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal Associação para a Inovação e Desenvolvimento da FCT, Portugal Universidade de Lisboa Faculdade de Ciências, Portugal Universidade de Lisboa Centro de Ecologia Evolução e Alterações Ambientais, Portugal Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo, Portugal Universidade de Évora, Portugal Universidade Nova de Lisboa Centro de Investigação em Ambiente e Sustentabilidade, Portugal Universidade NOVA de Lisboa, Portugal |
Fundação para a Ciência e a Tecnologia
Ongoing
|
2019/06/01 - 2022/11/13 | Mechanisms underlying JAK-STAT overactivation in Lama2-deficient congenital muscular dystrophy
CEECIND/01589/2017
Researcher
Centro de Ecologia Evolução e Alterações Ambientais, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2018/06/01 - 2022/05/31 | Metabolic adaptation to infectious diseases
PTDC/SAU-INF/29411/2017
Fundação Calouste Gulbenkian, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2019/01/01 - 2019/12/31 | Instituto Gulbenkian de Ciência
UID/Multi/04555/2019
Fundação Calouste Gulbenkian, Portugal
Instituto Gulbenkian de Ciência, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2015/06/01 - 2018/09/30 | DNA Damage and Disease Tolerance
SFRH/BPD/101608/2014
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2009/01/01 - 2012/12/31 | ROLES OF HUMAN RAP1 PROTEIN IN TELOMERE MAINTENANCE AND GENOMIC INTEGRITY
SFRH/BD/47326/2008
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Other
Designation | Funders | |
---|---|---|
2021/12 - Current | Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases
CA20121
Work Group Member
European Cooperation in Science and Technology, Belgium
|
Ongoing
|
2009/10/01 - 2009/10/31 | STSM BM0703: European Cooperation in Science and Technology (COST)-Cancer and Genomic Control of Integrity (CANGENIN)
PhD Student Fellow
Danish Cancer Society Research Center, Denmark
|
Concluded
|
Outputs
Publications
Book chapter |
|
Conference poster |
|
Journal article |
|
Preprint |
|
Other
Other output |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2024/12/12 | Mouse and human models to test LAMA2-MD therapeutic approaches | CE3C: the 10th Frontiers in E3
CE3C (Lisbon, Portugal)
|
2024/10/10 | Laminin-a2 chain deficiency leads to multi-organ oxidative stress | 8th BenBedPhar Scientific Meeting, Lisbon, Portugal
COST Action - BenBedPhar (Lisbon, Portugal)
|
2024/03/05 | Qual a importância da matriz extracelular para a célula?! | NEBFCUL - XII Jornadas de Investigação em Biologia
Faculty of Sciences, University of Lisbon (Lisbon, Portugal)
|
2023/09/07 | Using p53 deletion to revert LAMA2-congenital muscular dystrophy | Frontiers in E3 - 9th cE3c annual meeting
(Lisbon, Portugal)
|
2023/09/07 | Lama2-deficiency impacts myoblast differentiation in a mouse model for LAMA2- congenital muscular dystrophy | Frontiers in E3 - 9th cE3c annual meeting
(Lisbon, Portugal)
|
2023/09/07 | Impact of environmental pollutants in the skin: cell physiology and genetic changes | cE3c 9th Annual Meeting - Frontiers in E3
(Lisbon, Portugal)
|
2021/10/01 | LAMA2-CMD: disease mechanisms in skeletal muscle and heart | Frontiers in E3 7th Annual Meeting
cE3c (Lisboa, Portugal)
|
2021/03/05 | Mecanismos de doença: o percurso de uma bióloga | IX Jornadas de Investigação em Biologia
NEB-FCUL (Lisboa, Portugal)
|
2020/10/28 | Studying the mechanisms that trigger congenital muscular dystrophy | Ciências Research Day 2020 |
2020/10/01 | Disease mechanisms in LAMA2-CMD: mitochondrial dysfunction | 6th cE3c Annual Meeting |
2018/06/04 | Heme regulation of glucose metabolism in bloodstream infections. SFRRI 2018, Lisbon, Portugal. | 19th SFRRI Biennial Meeting |
2018/03/15 | Metabolic adaptation as a protective strategy against infectious diseases; 14th International SPDM Symposium | 14th International SPDM Symposium
(Porto, Portugal)
|
2017/09/11 | Weis S, Carlos AR, et al (2017). Ferritin heavy chain controls glucose metabolism and affords disease tolerance in sepsis. International Sepsis Forum, Paris, France. | International Sepsis Forum |
2017/05/19 | Oral Presentation: Soares MP (2017) Metabolic Adaptation establishes disease tolerance to sepsis. American Thoracic Society 2017 International Conference, Washington, USA. | American Thoracic Society 2017 International Conference |
2011/05/03 | Roles of BRCA1 and CtIP in processing uncapped telomeres; Cold Spring Harbor Laboratory (CSHL) | Telomeres and Telomerase
Cold Spring Harbor Laboratory (CSHL) (Cold Spring Harbor, United States)
|
2008/09/01 | Protein Differential-Display Analysis in Enterococci from Portuguese Ewe's Artisanal Cheeses. Food Micro 2008 | Food Micro 2008, Dairy Microbiology
(Aberdeen, Scotland, United Kingdom)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2024/11/20 - Current | Establishment of a new gene therapy strategy for LAMA2-MD using mice and patient-derived 3D in vitro models.
Supervisor
|
PhD in Biology (PhD)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2024/09/16 - Current | Unravelling the first defects o f LAMA2 congenital muscular dystrophy: muscle stem
cells versus myofibers
Co-supervisor
|
Master in Molecular Biology and Genetics (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2024/09/16 - Current | LAMA2 MD: establishment of a new gene therapy strategy using patient
derived cell lines
Supervisor
|
Masters in Molecular Biology and Genetics (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2024/09/16 - Current | Dissecting how LAMA2 modulation impact melanoma progression in a 3D in vitro
model
Supervisor
|
Masters in Organismal and Evolutionary Biology (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2024/09/16 - Current | Analysis of the effect of hydrodynamism on the regulation of sea urchin
adhesive strength: a molecular and biomechanical approach
Co-supervisor
|
Masters in Molecular Biology and Genetics (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2024/01 - Current | Dissecting the impact of LAMA2-deficiency in melanoma onset and progression
Supervisor
|
PhD in Biology (PhD)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2021/03/01 - Current | The role of the extracellular environment in cancer
Supervisor of Ana Sofia Lopes
|
Centro de Ecologia Evolução e Alterações Ambientais, Portugal
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal |
2020/12/01 - Current | Disease mechanisms in LAMA2-deficiency: skeletal muscle and heart
Supervisor of Susana Martins
|
Centro de Ecologia Evolução e Alterações Ambientais, Portugal
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal |
2023/09/18 - 2024/11/26 | Establishing 3D models to dissect the role of basement membrane-cell communication in cancer
Supervisor
|
Master Degree in Organismal and Evolutionary Biology (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2023/09/18 - 2024/10/14 | Understanding how LAMA2 deficiency impacts organ homeostasis
Supervisor
|
Master in Organismal and Evolutionary Biology (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2022/09/19 - 2024/02/20 | Understanding the mechanisms at the onset of LAMA2-congenital muscular dystrophy
Co-supervisor
|
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2022/09/19 - 2024/01/16 | Impact of environmental pollutants in the skin: cell physiology and genetic changes
Supervisor
|
|
2022/09/19 - 2024/01/12 | LAMA2-CMD: establishment of a new gene therapy strategy using an in vitro model
Supervisor
|
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2022/09/19 - 2023/11 | Understanding the impact of alterations in the expression of LAMA2 in melanoma
Supervisor
|
|
2021/09/01 - 2022/10/18 | How Lama2-deficiency impacts myoblast differentiation in a mouse model for LAMA2-congenital muscular dystrophy
Co-supervisor
|
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2021/09/13 - 2022 | Characterizing the impact of LAMA2-deficiency in cancer cell lines
Supervisor of Inês Fonseca
|
Centro de Ecologia Evolução e Alterações Ambientais, Portugal
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal |
2020/09/07 - 2021/03/08 | The impact of Lama2-deficiency on cell cycle regulation and survival
Supervisor of Catarina Melo
|
Centro de Ecologia Evolução e Alterações Ambientais, Portugal
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal |
2018/09/01 - 2019/11/30 | A protective role for ATM in hemolytic conditions.
Supervisor
|
Instituto Gulbenkian de Ciência, Portugal
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2015/11/04 - 2015/11/06 | Organization of the Second Annual Joint Postdoctoral Meeting involving the IGC, ITQB, iBET, iMM and Champalimaud, Setubal,
Portugal (2015/11/04 - 2015/11/06)
Meeting (Co-organisor)
|
Instituto Gulbenkian de Ciência, Portugal |
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2020/06/03 - Current | Dia Aberto FCUL 2020, 2021
Other
|
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
|
2021/05/20 - 2021/05/21 | 27th Porto Cancer Meeting
Conference
|
27th Porto Cancer Meeting |
2017/04 - 2018/04 | Science Outreach Activities: Day of Immunology; practical presentation to the general public.
Other
|
Instituto Gulbenkian de Ciência, Portugal
|
2018 - 2018 | Science Outreach Activities: Open day of the Instituto Gulbenkian Ciência (IGC), Oeiras, Portugal.
Other
|
Instituto Gulbenkian de Ciência, Portugal
|
2010/06 - 2010/06 | Science Outreach Activities: Cancer Research UK's Race, Oxford, United Kingdom.
Other
|
University of Oxford Wolfson College, United Kingdom
|
Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
---|---|---|
2023/10/06 | Intersectional genetics system for stem cell selection
(Thesis) Main arguer
|
João Nabo (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2022/03/30 | The role of key post-translational modifications in the nuclear translocation of STAT3 dimers upon cytokine stimulation
(Thesis) Main arguer
|
Daniela Martins Alves (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
2019/05/08 | Estudo da presença de polimosfismo associados à resistência da P. falciparum aos ACTs em Timor Leste.
(Thesis) Main arguer
|
Patrícia Duarte (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
|
2019/04/03 | Caracterização da miogénese fetal em ratinhos modelo da distrofia muscular laminina 211-deficiente.
(Thesis) Main arguer
|
Ricardo Andrade (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
Association member
Society Organization name | Role | |
---|---|---|
2022/01/01 - Current | European Association for Cancer Research (EACR) | Member and Ambassador |
2022/01/01 - Current | Associação Portuguesa de Investigação em Cancro (ASPIC) | Member |
2021/12/29 - Current | COST Action CA20121 | Member and co-WG5 leader |
2014 - 2016 | Science Outreach Activities: Author on the website Mapping Ignorance (http://mappingignorance.org/), promoting scientific writing. | Author |
Committee member
Activity description Role |
Institution / Organization | |
---|---|---|
2021/06/01 - 2021/07/31 | 32nd International Biology Olympiad, Scientific Committee
Member
|
|
2014/10/01 - 2015/11/01 | Member of the postdoc committee at Instituto Gulbenkian Ciência (IGC); Organization of soft skills workshops’ with national
and international speakers and the Second Annual Joint Postdoctoral Meeting involving the IGC, ITQB, iBET, iMM and Champalimaud.
Member
|
Instituto Gulbenkian de Ciência, Portugal |
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2024/01/08 - Current | Invited seminar: Using gene therapy to cure muscle dystrophies | (Mestrado) | Universidade de Aveiro Instituto de Biomedicina, Portugal |
2022/09/05 - Current | Animal Physiology | (Licenciatura) | Universidade de Lisboa Faculdade de Ciências, Portugal |
2020/09/07 - Current | Physiology - lectures and practical courses https://fenix.ciencias.ulisboa.pt/degrees/bioquimica-564500436615216/disciplina-curricular/564680825249472 | Physiology (Bacharelato) | Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal |
2020/09/07 - Current | Seminars in Evolutionary and Developmental Biology - discussion classes https://fenix.ciencias.ulisboa.pt/courses/sbed-2254879305238640/pagina-inicial | Seminars in Evolutionary and Developmental Biology (Mestrado) | Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal |
2020/03/04 - Current | Genes and Molecules in Development. Lectures and Practical Course. https://fenix.ciencias.ulisboa.pt/courses/gmd-2254879305237611 | Genes and Molecules in Development (Mestrado) | Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal |
2020/02/27 - Current | Animal Development Biology. Lecturer. https://fenix.ciencias.ulisboa.pt/courses/bdani-566029444973860 | (Licenciatura) | Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal |
2016/02/22 - Current | Molecular and Cell Biology of Cancer - Genomic Instability and Cancer; Master Degree in Molecular Biology and Genetics, FCUL, Portugal. Invited lecturer. Two hour lecture per year. | Molecular and Cell Biology of Cancer (Mestrado) | Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal |
2013/11/08 - Current | Biomolecular Methods - Immunocytochemistry and Immunohistochemistry; Master Degree in Molecular Biology and Genetics. Invited lecturer. Two hour lecture per year. | Biomolecular Methods (Mestrado) | Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal |
Interview (newspaper / magazine)
Activity description | Newspaper / Forum | |
---|---|---|
2021/03/08 | Women in Science Book 2021 | Ciência Viva |
Interview (tv / radio show)
Program | Topic | |
---|---|---|
2020/10/27 - Current | 90 segundos Ciência | |
2020/02/25 - 2020/02/25 | Muito Barulho para Nada |
Journal scientific committee
Journal title (ISSN) | Publisher | |
---|---|---|
2022/02/01 - Current | International Journal of Molecular Sciences | MDPI |
2021/02/16 - 2021/11/16 | Frontiers in Genetics ( 1664-8021) | Frontiers |
Distinctions
Award
2019 | L'Oréal Portugal Medals of Honor for Women in Science 2019 |
2018 | Best poster award: A protective role for ATM in hemolytic conditions |
2017 | Hugo-Schottmöller Award of the German Sepsis Society, Weimar, Germany |
2017 | Best Abstract Award International Sepsis Forum, Paris, France |
2005 | Honorary Degree conferred by the “Fundação da Faculdade de Ciências da Universidade de Lisboa” distinguishing the freshmen
with the highest grades of the academic year 2003/2004.
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
|