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I graduated in Chemistry from Faculdade de Ciências da Universidade de Lisboa in 2003 and I received a PhD in Organic Chemistry in 2009 doing a joint PhD at the Universidade de Lisboa and Université Pierre et Marie Currie Paris VI in the field of carbohydrate chemistry. My PhD work was awarded with the prize for the best thesis in carbohydrate chemistry (Bernard Fournet - André Verbert Prix 2010) from the “Groupe Français des Glucides” (GFG). After my PhD and to improve my scientific knowledge and diverse my background, I decided to move to Dr. J. Jiménez-Barbero’s group at Centro Investigaciones Biológicas (CSIC/Madrid) for a post-doctoral experience (2009-2011). During that period, I became fascinated with NMR and how to exploit this technique to unveil molecular recognition events in distinct biological contexts, including in Glycosciences. In 2012 I returned to Portugal with an FCT Post-doctoral grant to initiate a new research line in the field of Glycosciences in the NMR research group led by E. Cabrita (UCIBIO FCT/NOVA). In 2013, I have obtained my first Principal Investigator project funding by Portuguese FCT to investigate interaction of glycan cancer antigens with selected antibodies and lectins. Our models provide structural insights to improve the rational-based design of glycan-based anticancer vaccines. The results were published in high impact scientific journals and further disseminated in several international conferences. This work marked my first steps towards independence and expertize in structural Glycosciences and I began to be directly approached for collaborations by research labs in EU and overseas. As a consequence, in Dec 2016, I was awarded the highly competitive and prestigious Investigator FCT contract scoring the highest mark in all evaluation steps and criterions. Since January 2017, I have been established an independent line of research applied to structural glycosciences, where I synergistically combine high-resolution NMR-based approaches with molecular modelling protocols, sustained by molecular biology and carbohydrate/chemoenzymatic synthesis to uncover key molecular mechanisms of glycan recognition and protein glycosylation in cancer-related systems. Recent highlights of my research team rely on the determination of the structural features behind the recognition of tumour-associated glycans and mimetics by immune-related lectins, as well as on the elucidation of the mechanism of mucins glycosylation by GalNAc-transferases enzymes. Over the last 3 years, I was also able to attract national and international funding as main coordinator of research projects (PTDC/BIA-MIB/31028/2017 and IF/00780/2015 in a total of 288K€) and as scientific representative of Grant Holder of a COST research network CA18132-GlycoNanoProbes (135K€/year), in the glycosciences field. I am currently supervise, 1 Post Doc, 3 PhD students and 1 MSc student and I have completed the supervision of 1 PhD (Best thesis Award 2020), 4 MSc students, 4 Research Fellow (under the scope of national projects) and 6 Research trainees. Finally, I have been also engaged in distinct commissions of trust, namely in the Individual Fellowships, Marie Sklodowska-Curie actions (MSCA). I interrupted my scientific activity twice (2013 and 2018) due to maternity leave. Finally, during my scientific career, I published 47 original research articles, reviews and book chapters with a total of more than 860 citations (h-index 17, scopus), besides 30 invited lectures and oral communications in international conferences.
Identification

Personal identification

Full name
Filipa Marcelo

Citation names

  • Marcelo, Filipa

Author identifiers

Ciência ID
2B1E-5587-3DF2
ORCID iD
0000-0001-5049-8511
Google Scholar ID
A1aKCckAAAAJ&hl
Researcher Id
C-9588-2013
Scopus Author Id
25635843200

Email addresses

  • filipa.marcelo@fct.unl.pt (Professional)

Telephones

Telephone
  • 212948300 Ext.: 11401 (Professional)

Addresses

  • Gab 303, Lab 302, Departamento de Química, Faculdade de Ciências e Tecnologia Universidade NOVA de Lisboa, 2829-516, Caparica, Almada, Portugal (Professional)

Websites

  • https://www.requimte.pt/ucibio/people/filipa-marcelo (Professional)

Knowledge fields

  • Exact Sciences - Chemical Sciences
  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Biochemical Research Methods

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Advanced (C1) Advanced (C1) Upper intermediate (B2) Advanced (C1) Advanced (C1)
French Elementary (A2) Intermediate (B1) Elementary (A2) Intermediate (B1) Elementary (A2)
Education
Degree Classification
2005/01/01 - 2009/12/30
Concluded
Chemistry - Organic Chemistry (Doutoramento)
Universidade de Lisboa Faculdade de Ciências, Portugal

Université Pierre et Marie Curie - Paris VI, France
"Total Synthesis and Stereochemical Assignment of Miharamycins" (THESIS/DISSERTATION)
Cum Laude
1999/10/01 - 2003/10/31
Concluded
Chemistry (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Synthesis of New Oxime Carbamates" (THESIS/DISSERTATION)
20 out of 20
Affiliation

Science

2016/12/01 - 2021/11/30 Auxiliary Researcher (Research)
Associação para a Inovação e Desenvolvimento da FCT, Portugal
2012/01/01 - 2016/11/30 Postdoc (Research)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2009/01/01 - 2011/12/31 Postdoc (Research)
Centro de Investigaciones Biológicas, Spain
Projects

Grant

Designation Funders
2019 - 2023/02/28 Functional Glycoananomaterials for the Development of Diagnosis and Targeted Therapeutic Probes; MC member, Scientific representative of the Grant Holder. Funding ca. 135K€/year
COST CA18132
Researcher
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
European Commission
2016 - 2021/11/30 Advances into the Glycome: From a Structural viewpoint to Function in human Health and Disease. Funding 50K€
IF/00780/2015
Principal investigator
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Ministério da Ciência, Tecnologia e Inovação

Fundação para a Ciência e a Tecnologia
2018 - 2021/09/30 Advances in MUC1 Glycan Cancer Antigens: From structure to function in the fight against cancer; Funding 238K€
PTDC/BIA-MIB/31028/2017
Principal investigator
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia
2020 - 2021/08/31 Glycan-human microbiome interaction: glycan diversity and recognition in the human gut with impact on health and nutrition; Leader of the NMR Task. Funding 234K€
PTDC/BIA-MIB/31730/2017
Researcher
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia
2017 - 2021/05/31 Infrastructure Project No 22161 - National NMR Network (PTNMR):
Project No 22161, LISBOA-01-0145-FEDER-022161 - PINFRA/22161/2016
Researcher
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Fundação para a Ciência e a Tecnologia
2015 - 2019/03/31 Challenging organic synthesis inspired by nature - from natural products chemistry to drug discovery: MC member
COST CM1407
Researcher
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
European Commission
2013 - 2016/05/31 NMR Net - National Facility for Nuclear Magnetic Resonance: from Molecular Structure and Dynamics to Protein Function, Cell Physiology, and Metabolomics
RECI/BBB-BQB/0230/2012
Researcher
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação para a Ciência e a Tecnologia
2013 - 2015/05 Specific interaction of tumour-associated MUC1 peptides and antibodies: 3D view by NMR and Modelling; Funding 50K€
EXPL/QEQ-MED/0799/2012
Principal investigator
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Fundação Ciência e Tecnologia, Ministério da Educação e Ciência
Outputs

Publications

Book chapter
  1. Maria João Romão; Teresa Sacadura Santos-Silva; Ana Luísa Carvalho; Eurico J Cabrita; Filipa Marcelo. 2018. "Structural elucidation of macromolecules". 30-91. Bentham Science Publishers Ltd.. https://novaresearch.unl.pt/en/publications/c3fd1472-fd9e-47c1-bfaf-e46062a3771e.
    10.2174/97816810870921180101
  2. Videira, Paula Alexandra; Marcelo, Filipa; Grewal, Ravneet Kaur. 2017. "Glycosyltransferase inhibitors: a promising strategy to pave a path from laboratory to therapy". In Carbohydrate Chemistry, 135-158. Royal Society of Chemistry. http://dx.doi.org/10.1039/9781788010641-00135.
    10.1039/9781788010641-00135
  3. Marcelo, F.; Cañada, F.J.; Jiménez-Barbero, J.. 2012. "The interaction of saccharides with antibodies. A 3D view by using NMR". 385-402. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892662575&partnerID=MN8TOARS.
    Published
  4. Ardá, Ana; Berbís, M. Álvaro; Blasco, Pilar; Canales, Angeles; Javier Cañada, F.; Carmen Fernández-Alonso, Ma; Marcelo, Filipa; Jiménez-Barbero, Jesús. 2012. "Recent advances on the application of NMR methods to study the conformation and recognition properties of carbohydrates". In Carbohydrate Chemistry, 192-214. Royal Society of Chemistry. http://dx.doi.org/10.1039/9781849734769-00192.
    Published • 10.1039/9781849734769-00192
Conference poster
  1. Marcelo, Filipa. 2020. "More than 20 posters as corresponding author and 12 as first author. From those posters as corresponding author two of them were selected for best poster award.".
  2. Marcelo, Filipa; Coelho, Helena. 2019. "The exquisite mechanism of binding of human macrophage galactose-type lectin - Best Poster Award". Paper presented in 1st Meeting COST ACTION 18132 (GLYCOnanoPROBES), Caparica, Portugal.
  3. Marcelo, Filipa; Coelho, Helena. 2018. "19F-NMR Spectroscopy shows that GalNAc-Ts glycosylation mechanism follows an induced-fit mechanism -Best Poster Award". Paper presented in VIII Ibero-American NMR Meeting (Lisbon, Portugal)..
Journal article
  1. de las Rivas, Matilde; Paul Daniel, Earnest James; Narimatsu, Yoshiki; Compañón, Ismael; Kato, Kentaro; Hermosilla, Pablo; Thureau, Aurélien; et al. 2020. "Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3". Nature Chemical Biology 16 (3): 351-360. http://dx.doi.org/10.1038/s41589-019-0444-x.
    10.1038/s41589-019-0444-x
  2. Gomes, A.S.; Ramos, H.; Gomes, S.; Loureiro, J.B.; Soares, J.; Barcherini, V.; Monti, P.; et al. 2020. "SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations". Biochimica et Biophysica Acta - General Subjects 1864 (1). http://www.scopus.com/inward/record.url?eid=2-s2.0-85073833530&partnerID=MN8TOARS.
    Published • 10.1016/j.bbagen.2019.129440
  3. Ribeiro, Diana O.; Viegas, Aldino; Pires, Virgínia M. R.; Medeiros-Silva, João; Bule, Pedro; Chai, Wengang; Marcelo, Filipa; et al. 2019. "Molecular basis for the preferential recognition of ß1,3-1,4-glucans by the family 11 carbohydrate-binding module from Clostridium thermocellum". The FEBS Journal. http://dx.doi.org/10.1111/febs.15162.
    10.1111/febs.15162
  4. Ana Diniz; Helena Coelho; Jorge S. Dias; Sandra J. Vliet; Jesús Jiménez-Barbero; Francisco Corzana; Eurico J. Cabrita; Filipa Marcelo. 2019. "The Plasticity of the Carbohydrate Recognition Domain Dictates the Exquisite Mechanism of Binding of Human Macrophage Galactose-Type Lectin". Chemistry – A European Journal 25 (61): 13945-13955. https://doi.org/10.1002/chem.201902780.
    Published • 10.1002/chem.201902780
  5. Marcelo, Filipa; Supekar, Nitin; Corzana, Francisco; van der Horst, Joost C.; Vuist, Ilona M.; Live, David; Boons, Geert-Jan P. H.; Smith, David F.; van Vliet, Sandra J.. 2019. "Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands". Journal of Biological Chemistry 294 (4): 1300-1311. http://dx.doi.org/10.1074/jbc.ra118.004957.
    10.1074/jbc.ra118.004957
  6. Siopa, Filipa; Frade, Raquel F. M.; Diniz, Ana; Andrade, Joana M.; Nicolai, Marisa; Meirinhos, Ana; Lucas, Susana D.; et al. 2018. "Acetylcholinesterase Choline-Based Ionic Liquid Inhibitors: In Vitro and in Silico Molecular Docking Studies". ACS Omega 3 (12): 17145-17154. http://dx.doi.org/10.1021/acsomega.8b02347.
    10.1021/acsomega.8b02347
  7. de las Rivas, Matilde; Paul Daniel, Earnest James; Coelho, Helena; Lira-Navarrete, Erandi; Raich, Lluis; Compañón, Ismael; Diniz, Ana; et al. 2018. "Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4". ACS Central Science 4 (9): 1274-1290. http://dx.doi.org/10.1021/acscentsci.8b00488.
    Open access • 10.1021/acscentsci.8b00488
  8. Santarsia, Sabrina; Grosso, Ana Sofia; Trovão, Filipa; Jiménez-Barbero, Jesús; Carvalho, Ana Luísa; Nativi, Cristina; Marcelo, Filipa. 2018. "Molecular Recognition of a Thomsen-Friedenreich Antigen Mimetic Targeting Human Galectin-3". ChemMedChem 13 (19): 2030-2036. http://dx.doi.org/10.1002/cmdc.201800525.
    10.1002/cmdc.201800525
  9. de las Rivas, Matilde; Coelho, Helena; Diniz, Ana; Lira-Navarrete, Erandi; Compañón, Ismael; Jiménez-Barbero, Jesús; Schjoldager, Katrine T.; et al. 2018. "Structural Analysis of a GalNAc-T2 Mutant Reveals an Induced-Fit Catalytic Mechanism for GalNAc-Ts". Chemistry - A European Journal 24 (33): 8382-8392. http://dx.doi.org/10.1002/chem.201800701.
    Published • 10.1002/chem.201800701
  10. de las Rivas, Matilde; Lira-Navarrete, Erandi; Daniel, Earnest James Paul; Compañón, Ismael; Coelho, Helena; Diniz, Ana; Jiménez-Barbero, Jesús; et al. 2017. "The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences". Nature Communications 8 (1). http://dx.doi.org/10.1038/s41467-017-02006-0.
    Open access • Published • 10.1038/s41467-017-02006-0
  11. Ana Diniz; Jorge S. Dias; Jesús Jiménez-Barbero; Filipa Marcelo; Eurico J. Cabrita. 2017. "Protein-Glycan Quinary Interactions in Crowding Environment Unveiled by NMR Spectroscopy". Chemistry - A European Journal 23 (53): 13213-13220. https://doi.org/10.1002/chem.201702800.
    10.1002/chem.201702800
  12. Rosa, Mònica; Gonzalez-Nunez, Verónica; Barreto-Valer, Katherine; Marcelo, Filipa; Sánchez-Sánchez, Julia; Calle, Luis P.; Arévalo, Juan C.; et al. 2017. "Role of the sugar moiety on the opioid receptor binding and conformation of a series of enkephalin neoglycopeptides". Bioorganic & Medicinal Chemistry 25 (7): 2260-2265. http://dx.doi.org/10.1016/j.bmc.2017.02.052.
    Published • 10.1016/j.bmc.2017.02.052
  13. Rosa, Mònica; Marcelo, Filipa; Calle, Luis P.; Rougeot, Catherine; Jiménez-Barbero, Jesús; Arsequell, Gemma; Valencia, Gregorio. 2015. "Influence of polar side chains modifications on the dual enkephalinase inhibitory activity and conformation of human opiorphin, a pain perception related peptide". Bioorganic & Medicinal Chemistry Letters 25 (22): 5190-5193. http://dx.doi.org/10.1016/j.bmcl.2015.09.071.
    Published • 10.1016/j.bmcl.2015.09.071
  14. Coelho, Helena; Matsushita, Takahiko; Artigas, Gerard; Hinou, Hiroshi; Cañada, F. Javier; Lo-Man, Richard; Leclerc, Claude; et al. 2015. "The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR". Journal of the American Chemical Society 137 (39): 12438-12441. http://dx.doi.org/10.1021/jacs.5b06787.
    Published • 10.1021/jacs.5b06787
  15. Blázquez-Sánchez, M. Teresa; Marcelo, Filipa; Fernández-Alonso, María del Carmen; del Villar-Guerra, Rafael; Samadi, Abdelouahid; Cañada, F. Javier; Jiménez-Barbero, Jesús; Vicent, Cristina. 2015. "D- andL-Mannose-Containing glyco-­Oligoamides Show Distinct Recognition Properties When Interacting with DNA". European Journal of Organic Chemistry 2015 (28): 6180-6193. http://dx.doi.org/10.1002/ejoc.201500740.
    Published • 10.1002/ejoc.201500740
  16. Madariaga, David; Martínez-Sáez, Nuria; Somovilla, Víctor J.; Coelho, Helena; Valero-González, Jessika; Castro-López, Jorge; Asensio, Juan L.; et al. 2015. "Detection of Tumor-Associated Glycopeptides by Lectins: The Peptide Context Modulates Carbohydrate Recognition". ACS Chemical Biology 10 (3): 747-756. http://dx.doi.org/10.1021/cb500855x.
    10.1021/cb500855x
  17. Huecas, S.; Marcelo, F.; Perona, A.; Ruiz-Ávila, L.B.; Morreale, A.; Canada, F.J.; Jiménez-Barbero, J.; Andreu, J.M.. 2015. "Beyond a Fluorescent Probe: Inhibition of Cell Division Protein FtsZ by mant-GTP Elucidated by NMR and Biochemical Approaches". ACS Chemical Biology 10 (10): 2382-2392. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944810084&partnerID=MN8TOARS.
    Published • 10.1021/acschembio.5b00444
  18. Jesus, Ana R.; Dias, Catarina; Matos, Ana M.; de Almeida, Rodrigo F. M.; Viana, Ana S.; Marcelo, Filipa; Ribeiro, Rogério T.; et al. 2014. "Exploiting the Therapeutic Potential of 8-ß-d-Glucopyranosylgenistein: Synthesis, Antidiabetic Activity, and Molecular Interaction with Islet Amyloid Polypeptide and Amyloid ß-Peptide (1–42)". Journal of Medicinal Chemistry 57 (22): 9463-9472. http://dx.doi.org/10.1021/jm501069h.
    Published • 10.1021/jm501069h
  19. Blázquez-Sánchez, M. Teresa; Marcelo, Filipa; Fernández-Alonso, M. Carmen; Poveda, Ana; Jiménez-Barbero, Jesús; Vicent, Cristina. 2014. "Cooperative Hydrogen Bonding in Glyco-Oligoamides: DNA Minor Groove Binders in Aqueous Media". Chemistry - A European Journal 20 (52): 17640-17652. http://dx.doi.org/10.1002/chem.201403911.
    10.1002/chem.201403911
  20. Marcelo, Filipa; Garcia-Martin, Fayna; Matsushita, Takahiko; Sardinha, João; Coelho, Helena; Oude-Vrielink, Anneloes; Koller, Christiane; et al. 2014. "Delineating Binding Modes of Gal/GalNAc and Structural Elements of the Molecular Recognition of Tumor-Associated Mucin Glycopeptides by the Human Macrophage Galactose-Type Lectin". Chemistry - A European Journal 20 (49): 16147-16155. http://dx.doi.org/10.1002/chem.201404566.
    Published • 10.1002/chem.201404566
  21. Marcelo, Filipa; Huecas, Sonia; Ruiz-Ávila, Laura B.; Cañada, F. Javier; Perona, Almudena; Poveda, Ana; Martín-Santamaría, Sonsoles; et al. 2013. "Interactions of Bacterial Cell Division Protein FtsZ with C8-Substituted Guanine Nucleotide Inhibitors. A Combined NMR, Biochemical and Molecular Modeling Perspective". Journal of the American Chemical Society 135 (44): 16418-16428. http://dx.doi.org/10.1021/ja405515r.
    10.1021/ja405515r
  22. Guitet, Maxime; Zhang, Pinglu; Marcelo, Filipa; Tugny, Coralie; Jiménez-Barbero, Jesús; Buriez, Olivier; Amatore, Christian; et al. 2013. "NHC-Capped Cyclodextrins (ICyDs): Insulated Metal Complexes, Commutable Multicoordination Sphere, and Cavity-Dependent Catalysis". Angewandte Chemie International Edition 52 (28): 7213-7218. http://dx.doi.org/10.1002/anie.201301225.
    Published • 10.1002/anie.201301225
  23. Guitet, Maxime; Marcelo, Filipa; de Beaumais, Ségolène Adam; Zhang, Yongmin; Jiménez-Barbero, Jesús; Tilloy, Sébastien; Monflier, Eric; Ménand, Mickaël; Sollogoub, Matthieu. 2013. "Diametrically Opposed Carbenes on an a-Cyclodextrin: Synthesis, Characterization of Organometallic Complexes and Suzuki-Miyaura Coupling in Ethanol and in Water". European Journal of Organic Chemistry 2013 (18): 3691-3699. http://dx.doi.org/10.1002/ejoc.201300190.
    10.1002/ejoc.201300190
  24. Marcelo, Filipa; Dias, Catarina; Martins, Alice; Madeira, Paulo J.; Jorge, Tiago; Florêncio, M. Helena; Cañada, F. Javier; et al. 2013. "Molecular Recognition of Rosmarinic Acid fromSalvia sclareoidesExtracts by Acetylcholinesterase: A New Binding Site Detected by NMR Spectroscopy". Chemistry - A European Journal 19 (21): 6641-6649. http://dx.doi.org/10.1002/chem.201203966.
    Published • 10.1002/chem.201203966
  25. Airoldi, Cristina; Sironi, Erika; Dias, Catarina; Marcelo, Filipa; Martins, Alice; Rauter, Amélia Pilar; Nicotra, Francesco; Jimenez-Barbero, Jesus. 2013. "Natural Compounds against Alzheimer’s Disease: Molecular Recognition of Aß1-42 Peptide bySalvia sclareoidesExtract and its Major Component, Rosmarinic Acid, as Investigated by NMR". Chemistry - An Asian Journal 8 (3): 596-602. http://dx.doi.org/10.1002/asia.201201063.
    10.1002/asia.201201063
  26. del Carmen Fernandez-Alonso, Maria; Diaz, Dolores; Alvaro Berbis, Manuel; Marcelo, Filipa; Canada, Javier; Jimenez-Barbero, Jesus. 2012. "Protein-Carbohydrate Interactions Studied by NMR: From Molecular Recognition to Drug Design". Current Protein and Peptide Science 13 (8): 816-830. http://dx.doi.org/10.2174/138920312804871175.
    Published • 10.2174/138920312804871175
  27. Amorim, Luis; Marcelo, Filipa; Désiré, Jérôme; Sollogoub, Matthieu; Jiménez-Barbero, Jesús; Blériot, Yves. 2012. "Synthesis and conformational analysis of bicyclic mimics of a- and ß-d-glucopyranosides adopting the biologically relevant 2,5B conformation". Carbohydrate Research 361: 219-224. http://dx.doi.org/10.1016/j.carres.2012.07.005.
    Published • 10.1016/j.carres.2012.07.005
  28. Rosa, Mònica; Arsequell, Gemma; Rougeot, Catherine; Calle, Luis P.; Marcelo, Filipa; Pinto, Marta; Centeno, Nuria B.; Jiménez-Barbero, Jesús; Valencia, Gregorio. 2012. "Structure–Activity Relationship Study of Opiorphin, a Human Dual Ectopeptidase Inhibitor with Antinociceptive Properties". Journal of Medicinal Chemistry 55 (3): 1181-1188. http://dx.doi.org/10.1021/jm2012112.
    10.1021/jm2012112
  29. Marcelo, Filipa; Cañada, Francisco Javier; André, Sabine; Colombo, Cinzia; Doro, Fabio; Gabius, Hans-Joachim; Bernardi, Anna; Jiménez-Barbero, Jesús. 2012. "a-N-Linked glycopeptides: conformational analysis and bioactivity as lectin ligands". Organic & Biomolecular Chemistry 10 (30): 5916. http://dx.doi.org/10.1039/c2ob07135e.
    Published • 10.1039/c2ob07135e
  30. Luo, Bo; Marcelo, Filipa; Désiré, Jérôme; Zhang, Yongmin; Sollogoub, Matthieu; Kato, Atsushi; Adachi, Isao; et al. 2011. "Synthesis, Conformational Analysis, and Evaluation as Glycosidase Inhibitors of Two Ether-Bridged Iminosugars". Journal of Carbohydrate Chemistry 30 (7-9): 641-654. http://dx.doi.org/10.1080/07328303.2011.630547.
    Published • 10.1080/07328303.2011.630547
  31. Amorim, Luis; Marcelo, Filipa; Rousseau, Cyril; Nieto, Lidia; Jiménez-Barbero, Jesús; Marrot, Jérôme; Rauter, Amélia P.; et al. 2011. "Direct Experimental Evidence for the High Chemical Reactivity of a- and ß-Xylopyranosides Adopting a 2,5 B Conformation in Glycosyl Transfer". Chemistry – A European Journal 17 (26): 7345-7356. http://dx.doi.org/10.1002/chem.201003251.
    Published • 10.1002/chem.201003251
  32. Corzana, Francisco; Busto, Jesús H.; Marcelo, Filipa; García de Luis, Marisa; Asensio, Juan Luis; Martín-Santamaría, Sonsoles; Jiménez-Barbero, Jesús; Avenoza, Alberto; Peregrina, Jesús M.. 2011. "Engineering O -Glycosylation Points in Non-extended Peptides: Implications for the Molecular Recognition of Short Tumor-Associated Glycopeptides". Chemistry – A European Journal 17 (11): 3105-3110. http://dx.doi.org/10.1002/chem.201003124.
    Published • 10.1002/chem.201003124
  33. Peñalver, Pablo; Marcelo, Filipa; Jiménez-Barbero, Jesús; Vicent, Cristina. 2011. "Carbohydrate Recognition at the Minor-Groove of the Self-Complementary Duplex d(CGCGAATTCGCG) 2 by a Synthetic Glyco-oligoamide". Chemistry – A European Journal 17 (16): 4561-4570. http://dx.doi.org/10.1002/chem.201003027.
    10.1002/chem.201003027
  34. Arsequell, Gemma; Rosa, Mònica; Mayato, Carlos; Dorta, Rosa L.; Gonzalez-Nunez, Verónica; Barreto-Valer, Katherine; Marcelo, Filipa; et al. 2011. "Synthesis, biological evaluation and structural characterization of novel glycopeptide analogues of nociceptin N/OFQ". Organic & Biomolecular Chemistry 9 (17): 6133. http://dx.doi.org/10.1039/c1ob05197k.
    10.1039/c1ob05197k
  35. Corzana, Francisco; Busto, Jesús H.; Marcelo, Filipa; García de Luis, Marisa; Asensio, Juan L.; Martín-Santamaría, Sonsoles; Sáenz, Yolanda; et al. 2011. "Rational design of a Tn antigen mimic". Chemical Communications 47 (18): 5319. http://dx.doi.org/10.1039/c1cc10192g.
    Published • 10.1039/c1cc10192g
  36. Cipolla, Laura; Airoldi, Cristina; Bini, Davide; Gregori, Maria; Marcelo, Filipa; Jiménez-Barbero, Jesús; Nicotra, Francesco. 2010. "Fructose-Based Proline Analogues: Exploring the Prolyl trans/cis-Amide Rotamer Population in Model Peptides". European Journal of Organic Chemistry 2011 (1): 128-136. http://dx.doi.org/10.1002/ejoc.201000983.
    Published • 10.1002/ejoc.201000983
  37. Li, Hongqing; Marcelo, Filipa; Bello, Claudia; Vogel, Pierre; Butters, Terry D.; Rauter, Amélia P.; Zhang, Yongmin; Sollogoub, Matthieu; Blériot, Yves. 2009. "Design and synthesis of acetamido tri- and tetra-hydroxyazepanes: Potent and selective ß-N-acetylhexosaminidase inhibitors". Bioorganic & Medicinal Chemistry 17 (15): 5598-5604. http://dx.doi.org/10.1016/j.bmc.2009.06.022.
    Published • 10.1016/j.bmc.2009.06.022
  38. Marcelo, Filipa; Silva, Filipa V.M.; Goulart, Margarida; Justino, Jorge; Sinaÿ, Pierre; Blériot, Yves; Rauter, Amélia P.. 2009. "Synthesis of novel purine nucleosides towards a selective inhibition of human butyrylcholinesterase". Bioorganic & Medicinal Chemistry 17 (14): 5106-5116. http://dx.doi.org/10.1016/j.bmc.2009.05.057.
    Published • 10.1016/j.bmc.2009.05.057
  39. Marcelo, Filipa; He, Yuan; Yuzwa, Scott A.; Nieto, Lidia; Jime´nez-Barbero, Jesu´s; Sollogoub, Matthieu; Vocadlo, David J.; Davies, Gideon D.; Ble´riot, Yves. 2009. "Molecular Basis for Inhibition of GH84 Glycoside Hydrolases by Substituted Azepanes: Conformational Flexibility Enables Probing of Substrate Distortion". Journal of the American Chemical Society 131 (15): 5390-5392. http://dx.doi.org/10.1021/ja809776r.
    10.1021/ja809776r
  40. Rauter, Amélia; Blériot, Yves; Marcelo, Filipa; Abou-Jneid, Robert; Sollogoub, Matthieu; Marrot, Jérôme. 2009. "Total Synthesis of the Epimer at C-6' of the Miharamycin B Framework". Synlett 2009 (08): 1269-1272. http://dx.doi.org/10.1055/s-0029-1216733.
    10.1055/s-0029-1216733
  41. Marcelo, Filipa; Jiménez-Barbero, Jesús; Marrot, Jérôme; Rauter, Amélia P.; Sinaÿ, Pierre; Blériot, Yves. 2008. "Stereochemical Assignment and First Synthesis of the Core of Miharamycin Antibiotics". Chemistry - A European Journal 14 (32): 10066-10073. http://dx.doi.org/10.1002/chem.200801826.
    Published • 10.1002/chem.200801826
  42. Gouveia, L.; Nobre, B.P.; Marcelo, F.M.; Mrejen, S.; Cardoso, M.T.; Palavra, A.F.; Mendes, R.L.. 2007. "Functional food oil coloured by pigments extracted from microalgae with supercritical CO2". Food Chemistry 101 (2): 717-723. http://dx.doi.org/10.1016/j.foodchem.2006.02.027.
    Published • 10.1016/j.foodchem.2006.02.027
  43. Nobre, Beatriz; Marcelo, Filipa; Passos, Renata; Beirão, Luis; Palavra, António; Gouveia, Luísa; Mendes, Rui. 2006. "Supercritical carbon dioxide extraction of astaxanthin and other carotenoids from the microalga Haematococcus pluvialis". European Food Research and Technology 223 (6): 787-790. http://dx.doi.org/10.1007/s00217-006-0270-8.
    Published • 10.1007/s00217-006-0270-8
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/09/03 Advances into Mucin Glycosylation and Recognition 13th International Meeting of the Portuguese Carbohydrate Group
(Porto, Portugal)
2019/07/27 Decoding Glycan-Lectin Interactions in Cancer XXVI SPQ meeting
(Porto, Portugal)
2018/09/20 NMR Guide to Unravel Molecular Recognition Events Training School COST ACTION 1407
(Lisboa, Portugal)
2018/07/16 Structural Insights into mucin glycosylation and recognition 29th International Carhohydrate Symposium
(Lisboa, Portugal)
2017/07/06 Decoding Mucin Glycosylation and Recognition 19th European Carbohydrate Symposium – EUROCARB2017
(Barcelona, Spain)
2017/03/24 Deciphering mucin-based glycan specificity for cancer-related antibodies and lectins Glycovax Training event II
(Lisboa, Portugal)
2016/11/15 A NMR guide into molecular recognition events Invited Seminar at Chemistry and Biochemistry Department of Faculdade de Ciências da UL
(Lisboa, Portugal)
2016/10/06 My life as young women researcher - from PhD student to group leader, from daughter to mother Invited Seminar at Hokkaido University
(Sapporo, Japan)
2016/10/05 NMR guide to disentangle molecular recognition events Invited Seminar at Hokkaido University
(Sapporo)
2016/04/19 A NMR Guide into Molecular Recognition 1st Joint French-Portuguese NMR Conference
(Lisboa, Portugal)
2016/03/16 Mimicking cell-environment: Galectin-3 recognition studies under macromolecular crowding XII Biennial Carbohydrate meeting // III Biennial Chemical Biology meeting
(Madrid)
2015/12/17 Advances into the Glycome: From a structural viewpoint to function in human health and disease Invited Seminar at IRB Barcelona-Chemistry and Molecular Pharmacology Program
(Barcelona)
2015/09/24 A NMR guided approach to decipher carbohydrate-protein interactions GLYCOPHARM Glycobiology summer school
(Braga, Portugal)
2015/09/07 Unraveling the structural details of carbohydrate-protein interactions: A NMR and Molecular Modeling perspective 11th International Meeting of the Portuguese Carbohydrate Chemistry Group/ 6th Iberian Carbohydrate Meeting
(Viseu, Portugal)
2015/06/10 Molecular Recognition of tumor-associated MUC1 peptides by their specific receptors: lectins and antibodies 6th EuChemS Chemistry for Life Sciences
(Lisboa, Portugal)
2015/01/27 Unraveling ligand-protein interactions: 3D view by NMR and Molecular Modelling Invited seminar at Departamento de Química Universidad de la Rioja
(Logroño)
2015 NMR Molecular Recognition of tumor-associated MUC1 peptides by lectins and antibodies 1st Scientific Meeting COST Action CM1407
(Rome, Italy)
2014/09/22 Deciphering the structural details of carbohydrate-protein interactions: 3D view by NMR and Molecular Modeling VII GERMN Biennial Meeting / IV Iberian NMR Meeting / VI Iberoamerican NMR Meeting
(Alcalá de Henares, Spain)
2014/05/29 Molecular Recognition of tumor-associated mucin glycopeptides by the human macrophage galactose-type lectin Glycobiology and glycochemistry: Applications to human health and disease” organized by the European Molecular Biology Organization (EMBO)
(Lisboa, Portugal)
2012/09/27 Targeting the bacterial cell-division protein FtsZ. 3D view by NMR IV Ibero-American NMR Meeting
(Aveiro, Portugal)
2011/07/06 Molecular Recognition and Conformation Analysis of O- and N-Linked Glycopeptides 16th European Carbohydrate Symposium – Eurocarb 16
(Sorrento, Italy)
2011/04/15 Molecular Recognition and Conformation Analysis of O- and N-Linked Glycopeptides European Young Investigator Workshop on Carbohydrate Chemistry
(Lyon)
2010/10/17 Targeting the bacterial cell-division protein FtsZ COST Action D34 – Final Meeting
(Florence, Italy)
2010/06/17 Serum Albumin Interactions- The case of Flurbiprofen and its Acyl Glucuronide derivative XXIII Reunión Bienal de Química Orgánica
(Múrcia)
2010/04/23 NMR and Molecular Modeling insights on the Interactions of PC190723, a Cell Division Inhibitor, with FtsZ Chemical Tools for Molecular Recognition Studies: Synthesis and NMR characterization of bioactive molecules
(Milan)
2010/04/23 The interactions of Guanine Nucleotides with FtsZ studied by NMR and Molecular Modelling Targeting bacterial cell-division Estrutura y Función de Proteinas, VI Reunión de la Red Temática Nacional
(Madrid, Spain)
2008/09/12 Total Synthesis and Stereochemical Assignment of Miharamycin Antibiotics IV Iberian Carbohydrate Meeting - IX Jornadas De Carbohidratos
(Santiago de Compostela, Spain)
2008/05/27 Total Synthesis and Stereochemical Elucidation at C-6’ of Miharamycins Invited Seminar at CQB Faculdade de Ciências da Universidade de Lisboa
(Lisboa, Portugal)
2007/09/14 Synthetic Studies Towards the Miharamycins VII International Portuguese Meeting of Carbohydrates
(Oeiras, Portugal)
2005/06/12 Approaches Towards the Synthesis of Miharamycins Sugar Moiety European Meeting of Carbohydrates
(Cracow, Poland)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2019/09/01 - Current Deciphering the structural features of glycan-lectin interactions in the immune system
Supervisor of Carlos Lima
Biochemistry (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/07/01 - Current Post-doctoral supervision under the scope of project Advances in MUC1 Glycan Cancer Antigens: From structure to function in the fight against cancer (PTDC/BIA-MIB/31028/2017)
Supervisor of Helena Maria Nobre Coelho
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/11/01 - Current Targeting glycan-binding proteins towards the rational development of novel cancer immunomodulation therapies.
Supervisor of Ana Sofia Campos Grosso
Chemistry (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/05/01 - Current Structural insights into recognition and signalling of the MGL immunomodulatory receptor
Supervisor of Ana Catarina Ferreira Diniz
Chemistry (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/01/01 - Current A rational ligand design towards glycan-protein interactions: From chemical synthesis to NMR molecular recognition studies
Co-supervisor of João Manuel Barros
Chemistry (PhD)
Universidade de Lisboa Faculdade de Ciências, Portugal
2020/02/10 - 2020/03/31 Molecular recognition mechanism of MUC1-based mimetics glycopeptides by antibodies and MGL: 3D view by NMR
Supervisor of Pablo Adrian Guillen Poza
Scientific internship - collaboration with Hokaido University, Japan (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/09/01 - 2019/11/27 Molecular recognition of human macrophage galactose-type lectin by NMR
Supervisor of Rui Miguel Alegria Borralho
Bioorganic Chemistry (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/01/15 - 2019/06/19 Chemoenzymatic synthesis and structural analysis of MUC1 glycosylated fragments aberrantly expressed in cancer
Supervisor of Cátia Alexandra Oliveira Soares
Biochemistry (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/06/01 - 2019/03/24 NMR and Molecular Recognition of Compounds Related to the Immune System
Supervisor of Helena Maria Nobre Coelho
Biochemistry / Synthetic Chemistry (PhD)
Universidad del País Vasco - Campus Bizkaia, Spain

Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/09/01 - 2018/10/31 Molecular recognition of tumor-associated antigens by lectins and antibodies
Supervisor of Ana Sofia Campos Grosso
Bioorganic Chemistry (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/01/20 - 2018/06/15 Characterization of effects by the medium environment on protein functionality and structure
Co-supervisor of Philip Guilherme Capelo O’Toole
Biochemistry (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/01/20 - 2018/05/27 Molecular recognition of Tn- and STn-antigens by human macrophage C-type lectin
Supervisor of Sara Pinheiro
Biochemistry (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/01/20 - 2018/05/27 Descrimination of lectin domain function of GalNAc-T2/T3 enzymes during glycosylation of Mucin-1
Supervisor of Rodrigo Almeida Francisco
Biochemistry (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/10/19 - 2017/12/30 NMR molecular recognition of tumor-associated TF antigen and corresponding mimetics by the tissue lectin Galectin-3 - STSM funded by COST CA1407
Supervisor of Sabrina Santarsia
short-term scientific mission (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016/09/01 - 2017/12/11 Development of in-cell NMR methodologies
Co-supervisor of Claúdia Filipa Martins Afonso
Bioorganic Chemistry (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/01/15 - 2017/06/20 Molecular Recognition tumoral Thomsen-Friedenreich (TF) by human Galectin-3
Supervisor of Rui Miguel Alegria Borralho
Biochemistry (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/01/01 - 2016/05/03 Mimicking cell environment: carbohydrate-protein interactions under macromolecular crowding
Co-supervisor of Ana Catarina Ferreira Diniz
Biochemistry (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/01/20 - 2015/06/15 NMR Molecular recognition of MUC1 tumor-associated glycopeptides and the human macrophage galactose-type lectin
Supervisor of Chloé Richard
Biochemistry (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2019/06/01 - 2019/11/20 Organization of the 1st Meeting (Scientific meeting, MC meeting and Working Group meeting) of COST CA18132 GlycoNanoProbes (2019/11/18 - 2019/11/20)
Meeting (President of the Organising Committee)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2020/07/02 Protein-carbohydrate recognition in the biodegradation of the plant cell wall: Functional and structural studies using carbohydrate microarrays and X-ray crystallography
(Thesis) Arguer
Diana de Oliveira Ribeiro (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/04/28 NEW METHODOLOGIES FOR STUDYING CARBOHYDRATE-PROTEIN INTERACTIONS BY NUCLEAR MAGNETIC RESONANCE
(Thesis) Main arguer
BEATRIZ FERNÁNDEZ DE TORO RONDA (PhD)
Universidad Complutense de Madrid, Spain
2020/04/27 Nuclear Magnectic Resonance applied to the molecular recognition of fucose-derived ligands by DC-SIGN receptor
(Thesis) Main arguer
Pablo Valverde Sanchéz (PhD)
Universidad Complutense de Madrid, Spain
2019/12/20 Chitin and chitosan as reliable templates towards the carbohydrate backbone of bacterial peptidoglycan
(Thesis) Arguer
Fausto Daniel dos Santos Queda (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/03/25 NMR and molecular recognition of compounds related to the immune system
Supervisor
Helena Maria Nobre Coelho (PhD)
Universidade Nova de Lisboa, Portugal

Universidad del País Vasco, Spain
2018/12 Development of new antibiotics against Bacillus anthracis
(Thesis) Main arguer
João Pedro Almeida Pais (PhD)
Universidade de Lisboa Faculdade de Ciências, Portugal
2016/12 Cyclic peptides and small proteins in molecular recognition
(Thesis) Main arguer
Sónia Ciudad (PhD)
Universitat de Barcelona Facultat de Química, Spain
2016/10/17 Ligand discovery and structural-functional analysis of proteins involved in plant cell wall degradation
(Thesis) Main arguer
Raquel Lopes Costa (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/12 Synthesis of new antibiotic glycosides and computational studies on their interaction with model lipid bilayers
(Thesis) Main arguer
Rafael de Santana Nunes (Master)
Universidade de Lisboa Departamento de Química e Bioquímica, Portugal
2015/01/28 New Insights into Molecular Recognition of Epitopes Related to MUC1 Human Mucin by Lectins
(Thesis) Main arguer
David Madariaga Merino (PhD)
Universidad de la Rioja, Spain
2014/11/27 Synthesis of bacterial muropeptides for interaction studies with glycopeptide antibiotics
(Thesis) Main arguer
Cátia Vanessa de Almeida Santos (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Association member

Society Organization name Role
2019 - Current Portuguese Society of Chemistry Member
2011 - Current Portuguese NMR Network (PTNMR) Member
2009 - Current Spanish Royal Society of Chemistry Member
2009 - Current Member of the Nuclear Magnetic Resonance group of Spanish Royal Society of Chemistry Member

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019/01 - Current Advanced Topics in Medicinal Chemistry’ of the PhD programme i3DU Lectures: NMR toolbox to decipher protein-ligand interactions. Case studies applied to Glycosciences Medicinal Chemistry (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Lisboa Faculdade de Farmácia, Portugal
2017 - Current Co-cordinator of Glycobiology and Disease discipline in MSc programs of Biochemistry and Biochemistry in Health Glycochemistry and Glycobiology (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016 - Current Doctoral Program of NMR Applied to Chemistry, Materials and Biosciences of the FCT/NOVA Lectures: NMR-based experiments to investigate ligand-protein interactions Case studies applied to glycosciences NMR methodologies (Doutoramento) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/03 - Current Processes in Nutrition, Enviroment and health Lectures NMR tools to decipher glycan-protein interactions in human health and disease Processes in Nutrition, Environment and health (Mestrado integrado) Universidade de Lisboa Faculdade de Ciências, Portugal
2013 - 2013 Hands on course : NMR in Ligand-protein interactions studies Basics of NMR in structural elucidation of molecular and interactions (Curso médio) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Evaluation committee

Activity description
Role
Institution / Organization Funding entity
2017/10/07 - Current 2017, 2018, 2019 Evaluation of scientific proposals: Individual Fellowships, Marie Sklodowska-Curie actions (MSCA), H2020
Evaluator
2015 - Current Evaluation of National Funding Projects: Stand-Alone Projects from Austrian Science Fund (FWF)
Evaluator
Distinctions

Award

2020 Best Thesis Prize in Carbohydrate field to the PhD dissertation of Helena Maria Nobre Coelho
Spanish Royal Society of Chemistry, Spain
2019 Best Poster Award in 1st Meeting COST ACTION 18132 (GLYCOnanoPROBES)
2018 Best Poster Award VIII Ibero-American NMR Meeting
2010 Bernard Fournet - André Verbert Prix 2010 for the best PhD thesis
Groupe Français des Glucides (GFG), France
2008 Best Poster Award in IV Iberian Carbohydrate Meeting - IX Jornadas De Carbohidratos Santiago de Compostela
2007 Best Poster Award for the Best Poster in the EuroCarb XIV

Other distinction

2016 Competitive Contract Grant - FCT Investigator
Fundação para a Ciência e a Tecnologia, Portugal
2015 FCT Post-doctoral Fellowship SFRH/BPD/110734/2015
Fundação para a Ciência e a Tecnologia, Portugal
2010 FCT Post-doctoral Fellowship SFRH/BPD/65462/2009
Fundação para a Ciência e a Tecnologia, Portugal
2005 FCT Doctoral Fellowship SFRH/BD/17775/2004
Fundação para a Ciência e a Tecnologia, Portugal