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Identification

Personal identification

Full name
Maria Alexandra da Silva Paulo

Citation names

  • Paulo, Alexandra

Author identifiers

Ciência ID
2B13-DA6F-229F
ORCID iD
0000-0003-1433-5402

Email addresses

  • mapaulo@ff.ul.pt (Professional)
  • mapaulo@ff.ulisboa.pt (Professional)

Telephones

Telephone
  • 217946473 (Professional)

Addresses

  • Faculdade de Farmácia da Universidade de Lisboa. Av. Prof. Gama Pinto, 1649 003, Lisboa, Lisboa, Portugal (Professional)
  • iMed.ULisboa, Research Institute of Medicines, Faculty of Pharmacy, University of Lisbon, 1649 003, Lisbon, Lisbon, Portugal (Professional)

Websites

  • ORCID ID: 0000-0003-1433-5402 (Professional)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Medicinal Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Advanced (C1) Beginner (A1) Beginner (A1)
Spanish; Castilian Advanced (C1)
Education
Degree Classification
2014
Concluded
 Pharmacy (medicinal chemistry) (Título de Agregado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"n/a" (THESIS/DISSERTATION)
 unanimidade
1998
Concluded
 Pharmacy (Doctor of Philosophy)
University of London, United Kingdom
"Chemical and biological studies on african Cryptolepis species" (THESIS/DISSERTATION)
 Aprovado
1990
Concluded
 Pharmaceutical Sciences (Licenciatura)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"not applicable" (THESIS/DISSERTATION)
 16/20
Affiliation

Science

Category
Host institution 		Employer
2007/01/01 - Current Researcher (Research) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
1998 - 2007 Researcher (Research) Centro de Estudos Ciências Farmacêuticas / FFUL, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2023/07/13 - Current Associate Professor (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal
1998/06/02 - 2023/07/12 Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal

Others

Category
Host institution 		Employer
1991/07/01 - 1998/07/02 Researcher and Teaching Assistant Universidade de Lisboa Faculdade de Farmácia, Portugal
Projects

Grant

Designation Funders
2023/01/02 - Current Inquiring the druggability of DNAG4-helicase interactions with small molecules
2022.06099.PTDC
Principal investigator
Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing

Contract

Designation Funders
2021/03/29 - 2024/03/28 Targeting mutant p53 with tryptophanol-derived small molecules
PTDC/QUI-QOR/1304/2020
Co-Principal Investigator (Co-PI)
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/10 - 2021/09 A new approach to fight tuberculosis: co-drugs activated by mycobacterial esterases
PTDC/SAU-INF/28080/2017
Researcher
Fundação para a Ciência e a Tecnologia
2018/09 - 2021/08 DRUG DISCOVERY FOR p53 PPI-TARGETS
PTDC/QUI-QOR/29664/2017
Co-Principal Investigator (Co-PI)
Fundação para a Ciência e a Tecnologia
Concluded
2017 - 2020 POINT4PAC - Precision Oncology by Innovative Therapies and Technologies
SAICTPAC/0019/2015
Researcher
COMPETE and FCT through PROGRAMAS DE ATIVIDADES CONJUNTAS (PAC)
2013/06 - 2014/12 Exploring a new approach to target KRAS oncogene
EXPL/QEQ-MED/0502/2012
Principal investigator
Fundação para a Ciência e a Tecnologia
Concluded
2011/03 - 2014/08 TARGETING HEMOZOIN CRYSTAL STRUCTURE: A RATIONAL APPROACH TO THE DESIGN OF NOVEL ANTIMALARIALS
PTDC/SAU-FAR/114864/2009
Principal investigator
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Paulo, A.; Castillo, C.C.; Neidle, S.. "Targeting Promoter Quadruplex Nucleic Acids for Cancer Therapy". In Comprehensive Medicinal Chemistry III, edited by Chakalamannil, S; Rotella, DP; Ward, SE., 308-340. United Kingdom: Elsevier, 2017.
    Published • 10.1016/b978-0-12-409547-2.12397-2
  2. Lavrado J, et al; Paulo, Alexandra. "133. Synthesis of indolo(3,2-b)quinolin-11-one by acid-calalysed intramolecular double cyclization". In Comprehensive Organic Chemistry Experiments for the Laboratory Classroom, 585-589. The Royal Society of Chemistry, 2016.
    Published
  3. Lavrado, J. et al; Paulo, Alexandra. "138. Benzotriazole, a useful synthetic auxiliary in heterocyclizations". In Comprehensive Organic Chemistry Experiments for the Laboratory Classroom, 609-612. The Royal Society of Chemistry, 2016.
    Published
  4. Lavrado J, Moreira R; Paulo, Alexandra. "Chapter 5. Synthetic strategies towards bioactive indolo(3,2-b)quinolines". In Heterocyclic Targets in Advanced Organic Synthesis, 109-124. Research Signpost, 2011.
    Published
Conference abstract
  1. Cadoni, E et al.; Paulo, Alexandra. "New V-shape modular ligands: synthesis, biophysical, biochemical and in silico studies.". Paper presented in 6th International Meeting on Quadruplex Nucleic Acids, Prague, 2017.
    Published
  2. Paulo, Alexandra; Lavrado, J. et al. "KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indoloquinolines". Paper presented in 5th International Meeting on Quadruplex Nucleic Acids, Bordeaux, 2015.
    Published
  3. Paulo, Alexandra. "Broad SAR Exploration of 3-Piperidin-4-yl-1H-Indole Scaffold: towards a new antimalarial chemotype". Paper presented in EFMC-XXIII International Symposium on Medicinal Chemistry, ChemMedChem 2014; (special issue): 173, Lisbon, 2014.
    Published
  4. Paulo, Alexandra. "G-quadruplex stabilization by novel indolo(3,2-c)quinolines". Paper presented in EFMC – XXIII-International Symposium in Medicinal Chemistry, Lisbon, 2014.
    Published
  5. Paulo, Alexandra; Lavrado, J. et al. "Anticancer profile and G-quadruplex stabilization of indoloquinoline derivatives". Paper presented in 2º Encontro Nacional de Química Terapêutica, Rev. Port. Farmácia 2010, 52 (4): 13, Coimbra, 2010.
    Published
  6. Lavrado, J. et al; Paulo, Alexandra. "Studies towards the mechanism of antimalarial action of cryptolepine C-11 diamino derivatives.". Paper presented in 2º Encontro Nacional de Química Terapêutica, Rev. Port. Farmácia 2010, 52 (4): 33, Coimbra, 2010.
    Published
  7. Santos, SA et al;; Paulo, Alexandra. "Bis-alkylamine quindolone derivatives as new antimalarial leads". Paper presented in 2º Encontro Nacional de Química Terapêutica, Rev. Port. Farmácia 2010, 52 (4): 107, Coimbra, 2010.
    Published
  8. Dias, T, et al; Paulo, Alexandra. "Coreopsis tinctoria useful in glucose-intolerance therapeutics and diabetes prevention ?". Paper presented in 2nd Iberoamerican Congress on Phytotherapy. Revista de Fitoterapia, 9, (supl.1), Lisbon, 2009.
    Published
  9. Lavrado, J.; Paulo, Alexandra; Douglas, K.T. et al. "Antiplasmodial cryptolepine analogues: Interactions with single and double stranded oligonucleotides". Paper presented in 1º Encontro Nacional de Química Terapêutica. Rev. Port. Farmácia 2008, 52 (3): 97, Porto, 2008.
    Published
  10. Dias, T et al.; Paulo, Alexandra. "Coreopsis tinctoria infusions reverse streptozotocin-induced glucose-intolerance in rats.". Paper presented in 1º Encontro Nacional de Química Terapêutica. Rev. Port. Farmácia 2008, 52 (3): 76, Porto, 2008.
    Published
  11. Vítor, R et al.; Paulo, Alexandra. "Caracterização química do decocto das flores de Carqueja e estudo in vitro do seu efeito protector do endotélio". Paper presented in 1º Congresso da Sociedade Portuguesa de Ciências Farmacêuticas. Rev. Port. Farmácia 2003, 52 (supl.): 106, Lisboa, 2003.
    Published
  12. Teixeira G, Vítor, R;; Paulo, Alexandra. "caracteres morfoanatómicos e químicos da Carqueja.". Paper presented in 1º Congresso da Sociedade Portuguesa de Ciências Farmacêuticas. Rev. Port. Farmácia 2003, 52 (supl.): 107, 2003.
    Published
  13. Dias, C et al;; Paulo, Alexandra. "Estudo fitoquímico dos bolbos de Autonoë madeirensis.". Paper presented in 1º Congresso da Sociedade Portuguesa de Ciências Farmacêuticas. Rev. Port. Farmácia 2003, 52 (supl.): 170, 2003.
    Published
  14. Paulo, Alexandra. "The biological activity of Cryptolepis obtusa roots and their contained novel steroidal alkaloids". Paper presented in The 135th British Pharmaceutical Conference. J. Pharmacy and Pharmacology, 1998, 50 (suppl.):223, Eastbourne, 1998.
  15. Paulo, Alexandra; Houghton, PJ; Gomes ET; Duarte A et al. "Studies on the chemistry and in vitro antiplasmodial and antibacterial activity of cryptolepis sanguinolenta leaves.". Paper presented in The 134th British Pharmaceutical Conference. J. Pharmacy and Pharmacology, 1997, 49 (suppl. 4): 115, Scarborough, 1997.
    Published
  16. Paulo, Alexandra; Cabrita J, Pimentel M et al;. "Anti-campylobacter activity of african traditional medicines.". Paper presented in VII International Workshop on Campylobacter, Helicobacter and Related Organisms. Acta Gastro-Enterologica Belga 1993, 56 (supl): 13, Brussels, 1993.
    Published
Conference paper
  1. Paulo, Alexandra; Diniz MA, Silva O, Gomes ET. "Medicinal uses of plants from Guinea-Bissau". Paper presented in The biodiversity of african plants., 1996.
Journal article
  1. Bahls, Bárbara; Aljnadi, Israa M.; Emídio, Rita; Mendes, Eduarda; Paulo, Alexandra. "G-Quadruplexes in c-MYC Promoter as Targets for Cancer Therapy". Biomedicines 11 3 (2023): 969. http://dx.doi.org/10.3390/biomedicines11030969.
    Published • 10.3390/biomedicines11030969
  2. Mendes, Eduarda; Bahls, Bárbara; Aljnadi, Israa M.; Paulo, Alexandra. "Indoloquinolines as scaffolds for the design of potent G-quadruplex ligands". Bioorganic & Medicinal Chemistry Letters 72 (2022): 128862. http://dx.doi.org/10.1016/j.bmcl.2022.128862.
    10.1016/j.bmcl.2022.128862
  3. Mendes, Eduarda; Aljnadi, Israa M.; Bahls, Bárbara; Victor, Bruno L.; Paulo, Alexandra. "Major Achievements in the Design of Quadruplex-Interactive Small Molecules". Pharmaceuticals 15 3 (2022): 300. http://dx.doi.org/10.3390/ph15030300.
    10.3390/ph15030300
  4. Cadoni, Enrico; Magalhães, Pedro R.; Emídio, Rita M.; Mendes, Eduarda; Vítor, Jorge; Carvalho, Josué; Cruz, Carla; Victor, Bruno L.; Paulo, Alexandra. "New (Iso)quinolinyl-pyridine-2,6-dicarboxamide G-Quadruplex Stabilizers. A Structure-Activity Relationship Study". Pharmaceuticals 14 7 (2021): 669. http://dx.doi.org/10.3390/ph14070669.
    Open access • Published • 10.3390/ph14070669
  5. Ghosh, Rajat; Vitor, Jorge B.; Mendes, Eduarda; Paulo, Alexandra; Acharya, Pratap Chandra. "Stereoselective Synthesis of Spirooxindole Derivatives Using One-Pot Multicomponent Cycloaddition Reaction and Evaluation of Their Antiproliferative Efficacy". ACS Omega 5 42 (2020): 27332-27343. http://dx.doi.org/10.1021/acsomega.0c03675.
    Open access • Published • 10.1021/acsomega.0c03675
  6. Clemens Zwergel; Rossella Fioravanti; Giulia Stazi; Federica Sarno; Cecilia Battistelli; Annalisa Romanelli; Angela Nebbioso; et al. "Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation". Cancers 12 2 (2020): 447-447. https://doi.org/10.3390/cancers12020447.
    Open access • Published • 10.3390/cancers12020447
  7. Mendes, E.; Cadoni, E.; Carneiro, F.; Afonso, M.B.; Brito, H.; Lavrado, J.; dos Santos, D.J.V.A.; et al. "Combining 1,3-Ditriazolylbenzene and Quinoline to Discover a New G-Quadruplex-Interactive Small Molecule Active against Cancer Stem-Like Cells". ChemMedChem 14 14 (2019): 1325-1328.
    Published • 10.1002/cmdc.201900243
  8. Ana Rita Duarte; Enrico Cadoni; Ana S. Ressurreição; Rui Moreira; Alexandra Paulo. "Design of Modular G-quadruplex Ligands". ChemMedChem 13 (2018): 869-893. https://doi.org/10.1002/cmdc.201700747.
    Published • 10.1002/cmdc.201700747
  9. Mariz, I.F.A.; Pinto, S.; Lavrado, J.; Paulo, A.; Martinho, J.M.G.; Maçôas, E.M.S.. "Cryptolepine and quindoline: Understanding their photophysics". Physical Chemistry Chemical Physics 19 16 (2017): 10255-10263.
    10.1039/c7cp00455a
  10. Francisco, A.P.; Paulo, A.. "Oncogene expression modulation in cancer cell lines by DNA G-quadruplex-interactive small molecules". Current Medicinal Chemistry 24 (2017): 4873-4904.
    10.2174/0929867323666160829145055
  11. Santos, S.A.; Lukens, A.K.; Coelho, L.; Nogueira, F.; Wirth, D.F.; Mazitschek, R.; Moreira, R.; Paulo, A.. "Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype". European Journal of Medicinal Chemistry 102 (2015): 320-333.
    10.1016/j.ejmech.2015.07.047
  12. Lavrado, J.; Ohnmacht, S.A.; Correia, I.; Leitão, C.; Pisco, S.; Gunaratnam, M.; Moreira, R.; et al. "Indolo[3,2-c]quinoline G-quadruplex stabilizers: A structural analysis of binding to the human telomeric G-quadruplex". ChemMedChem 10 5 (2015): 836-849.
    10.1002/cmdc.201500067
  13. Figueiras, M.; Coelho, L.; Wicht, K.J.; Santos, S.A.; Lavrado, J.; Gut, J.; Rosenthal, P.J.; et al. "N10,N11-di-alkylamine indolo[3,2-b]quinolines as hemozoin inhibitors: Design, synthesis and antiplasmodial activity". Bioorganic and Medicinal Chemistry 23 7 (2015): 1530-1539.
    Published • 10.1016/j.bmc.2015.02.007
  14. Lavrado, J.; Brito, H.; Borralho, P.M.; Ohnmacht, S.A.; Kim, N.-S.; Leitão, C.; Pisco, S.; et al. "KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines". Scientific Reports 5 (2015): 9696.
    Open access • Published • 10.1038/srep09696
  15. Brito, H.; Martins, A.C.; Lavrado, J.; Mendes, E.; Francisco, A.P.; Santos, S.A.; Ohnmacht, S.A.; et al. "Targeting KRAS oncogene in colon cancer cells with 7-carboxylate Indolo[3,2-b] quinoline tri-alkylamine derivatives". PLoS ONE 10 5 (2015): e0126891.
    Open access • Published • 10.1371/journal.pone.0126891
  16. Paulo, A.; Figueiras, M.; MacHado, M.; Charneira, C.; Lavrado, J.; Santos, S.A.; Lopes, D.; et al. "Bis-alkylamine indolo[3,2- B ]quinolines as hemozoin ligands: Implications for antimalarial cytostatic and cytocidal activities". Journal of Medicinal Chemistry 57 8 (2014): 3295-3313.
    Published • 10.1021/jm500075d
  17. Santos, S.A.; Paulo, A.. "Small molecule inhibitors of multidrug resistance gene (MDR1) expression: Preclinical evaluation and mechanisms of action". Current Cancer Drug Targets 13 8 (2013): 814-828.
    Published • 10.2174/15680096113139990082
  18. Lavrado, J.; Borralho, P.M.; Ohnmacht, S.A.; Castro, R.E.; Rodrigues, C.M.P.; Moreira, R.; Dos Santos, D.J.V.A.; Neidle, S.; Paulo, A.. "Synthesis, G-quadruplex stabilisation, docking studies, and effect on cancer cells of indolo[3,2-b]quinolines with one, two, or three basic side chains". ChemMedChem 8 10 (2013): 1648-1661.
    Published • 10.1002/cmdc.201300288
  19. Rocha E Silva, L.F.; Montoia, A.; Amorim, R.C.N.; Melo, M.R.; Henrique, M.C.; Nunomura, S.M.; Costa, M.R.F.; et al. "Comparative in vitro and in vivo antimalarial activity of the indole alkaloids ellipticine, olivacine, cryptolepine and a synthetic cryptolepine analog". Phytomedicine 20 1 (2012): 71-76.
    Published • 10.1016/j.phymed.2012.09.008
  20. Lavrado, J.; MacKey, Z.; Hansell, E.; McKerrow, J.H.; Paulo, A.; Moreira, R.. "Antitrypanosomal and cysteine protease inhibitory activities of alkyldiamine cryptolepine derivatives". Bioorganic and Medicinal Chemistry Letters 22 19 (2012): 6256-6260.
    Published • 10.1016/j.bmcl.2012.07.104
  21. Lavrado, J.; Paulo, A.; Bichenkova, E.; Douglas, K.T.; Moreira, R.. "1H NMR spectroscopic identification of protonable sites in cryptolepines with C-11 substituents containing two amino functionalities". Magnetic Resonance in Chemistry 50 3 (2012): 216-220.
    Published • 10.1002/mrc.2873
  22. Dias, T.; Liu, B.; Jones, P.; Houghton, P.J.; Mota-Filipe, H.; Paulo, A.. "Cytoprotective effect of Coreopsis tinctoria extracts and flavonoids on tBHP and cytokine-induced cell injury in pancreatic MIN6 cells". Journal of Ethnopharmacology 139 2 (2012): 485-492.
    Published • 10.1016/j.jep.2011.11.038
  23. Lavrado, J.; Cabal, G.G.; Prudêncio, M.; Mota, M.M.; Gut, J.; Rosenthal, P.J.; Díaz, C.; et al. "Incorporation of basic side chains into cryptolepine scaffold: Structure-antimalarial activity relationships and mechanistic studies". Journal of Medicinal Chemistry 54 3 (2011): 734-750.
    10.1021/jm101383f
  24. Lavrado, J.; Reszka, A.P.; Moreira, R.; Neidle, S.; Paulo, A.. "C-11 diamino cryptolepine derivatives NSC748392, NSC748393, and NSC748394: Anticancer profile and G-quadruplex stabilization". Bioorganic and Medicinal Chemistry Letters 20 23 (2010): 7042-7045.
    Published • 10.1016/j.bmcl.2010.09.110
  25. Dias, T.; Bronze, M.R.; Houghton, P.J.; Mota-Filipe, H.; Paulo, A.. "The flavonoid-rich fraction of Coreopsis tinctoria promotes glucose tolerance regain through pancreatic function recovery in streptozotocin-induced glucose-intolerant rats". Journal of Ethnopharmacology 132 2 (2010): 483-490.
    Published • 10.1016/j.jep.2010.08.048
  26. Lavrado, J.; Gani, K.; Nobre, P.A.; Santos, S.A.; Figueiredo, P.; Lopes, D.; Rosário, V.D.; et al. "Bis-alkylamine quindolone derivatives as new antimalarial leads". Bioorganic and Medicinal Chemistry Letters 20 19 (2010): 5634-5637.
    Published • 10.1016/j.bmcl.2010.08.043
  27. Lavrado, J.; Moreira, R.; Paulo, A.. "Indoloquinolines as scaffolds for drug discovery". Current Medicinal Chemistry 17 22 (2010): 2348-2370.
    Published • 10.2174/092986710791698521
  28. Dias, T.; Mota-Filipe, H.; Liu, B.; Jones, P.; Houghton, P.J.; Paulo, A.. "Recovery of oral glucose tolerance by wistar rats after treatment with Coreopsis tinctoria infusion". Phytotherapy Research 24 5 (2010): 699-705.
    Published • 10.1002/ptr.2998
  29. Dias, T; Mota-Filipe, H; Houghton, PJ; Bronze, MR; Paulo, A. "The flavonoid rich fraction of Coreopsis tinctoria promotes glucose tolerance regain in streptozotocin-induced glucose-intolerant rats". Planta Medica 75 09 (2009): 1009. http://dx.doi.org/10.1055/s-0029-1234724.
    Published • 10.1055/s-0029-1234724
  30. Dias, T; Mota-Filipe, H; Houghton, PJ; Paulo, A. "Antihyperglycaemic effect of Coreopsis tinctoria aqueous extract in streptozotocin-induced glucose-intolerant rats". Planta Medica 74 09 (2008): 954. http://dx.doi.org/10.1055/s-0028-1084059.
    Published • 10.1055/s-0028-1084059
  31. Paulo, A.; Martins, S.; Branco, P.; Dias, T.; Borges, C.; Rodrigues, A.I.; Costa, M.D.C.; Teixeira, A.; Mota-Filipe, H.. "The opposing effects of the flavonoids isoquercitrin and sissotrin, isolated from Pterospartum tridentatum, on oral glucose tolerance in rats". Phytotherapy Research 22 4 (2008): 539-543.
    Published • 10.1002/ptr.2403
  32. Lavrado, J.; Paulo, A.; Gut, J.; Rosenthal, P.J.; Moreira, R.. "Cryptolepine analogues containing basic aminoalkyl side-chains at C-11: Synthesis, antiplasmodial activity, and cytotoxicity". Bioorganic and Medicinal Chemistry Letters 18 4 (2008): 1378-1381.
    Published • 10.1016/j.bmcl.2008.01.015
  33. Paulo, A.; Mota-Filipe, H.. "Effects of some natural 5-hydroxy-isoflavones on cultured human endothelial cells in presence and absence of hydrogen peroxide". Journal of Pharmacy and Pharmacology 58 1 (2006): 101-105.
    Published • 10.1211/jpp.58.1.0012
  34. Paulo, A.; Dias, C.; Jimeno, M.L.; Borges, C.; Nascimento, J.. "A new ¿7,22 sterol from the bulbs of Autonoë madeirensis". Fitoterapia 76 7-8 (2005): 765-767.
    Published • 10.1016/j.fitote.2005.06.002
  35. Vitor, R.F.; Mota-Filipe, H.; Teixeira, G.; Borges, C.; Rodrigues, A.I.; Teixeira, A.; Paulo, A.. "Flavonoids of an extract of Pterospartum tridentatum showing endothelial protection against oxidative injury". Journal of Ethnopharmacology 93 2-3 (2004): 363-370.
    Published • 10.1016/j.jep.2004.04.003
  36. Dias, C.; Paulo, A.; Nascimento, J.; Houghton, P.; Hawkes, J.E.; Conçalves, M.L.. "2-(4'-Aminobenzenamine)-pyrimidine, a New a-Antagonist from Autonoë madeirensis". Planta Medica 69 11 (2003): 1060-1062.
    Published • 10.1055/s-2003-45158
  37. Paulo, A.; Houghton, P.J.. "Chemotaxonomic analysis of the genus Cryptolepis". Biochemical Systematics and Ecology 31 2 (2003): 155-166.
    Published • 10.1016/S0305-1978(02)00075-3
  38. Dias, C.; Dias, M.; Borges, C.; Almoster-Ferreira, M.A.; Paulo, A.; Nascimento, J.. "Structural elucidation of natural 2-hydroxy di- and tricarboxylic acids and esters, phenylpropanoid esters and a flavonoid from Autonoë madeirensis using gas chromatographic/electron ionization, electrospray ionization and tandem mass spectrometric techniques". Journal of Mass Spectrometry 38 12 (2003): 1240-1244.
    Published • 10.1002/jms.554
  39. Paulo, A.; Gomes, E.T.; Steele, J.; Warhurst, D.C.; Houghton, P.J.. "Antiplasmodial activity of Cryptolepis sanguinolenta alkaloids from leaves and roots". Planta Medica 66 1 (2000): 30-34.
    Published • 10.1055/s-2000-11106
  40. Paulo, A.; Jimeno, M.L.; Gomes, E.T.; Houghton, P.J.. "Steroidal alkaloids from Cryptolepis obtusa". Phytochemistry 53 3 (2000): 417-422.
    Published • 10.1016/S0031-9422(99)00568-3
  41. Paulo, A.; Gomes, E.T.; Duarte, A.; Perrett, S.; Houghton, P.J.. "Chemical and antimicrobial studies on Cryptolepis obtusa leaves". Fitoterapia 68 6 (1997): 558-559.
    Published
  42. Paulo, A.; Gomes, E.T.; Houghton, P.J.. "New alkaloids from Cryptolepis sanguinolenta". Journal of Natural Products 58 10 (1995): 1485-1491.
    Published • 10.1021/np50124a002
  43. Paulo, A.; Duarte, A.; Gomes, E.T.. "In vitro antibacterial screening of Cryptolepis sanguinolenta alkaloids". Journal of Ethnopharmacology 44 2 (1994): 127-130.
    Published • 10.1016/0378-8741(94)90079-5
  44. Paulo, A.; Pimentel, M.; Viegas, S.; Pires, I.; Duarte, A.; Cabrita, J.; Gomes, E.T.. "Cryptolepis sanguinolenta activity against diarrhoeal bacteria". Journal of Ethnopharmacology 44 2 (1994): 73-77.
    Published • 10.1016/0378-8741(94)90071-X
Thesis / Dissertation
  1. Paulo, Alexandra. "Chemical and biological studies on african Cryptolepis species". PhD, King's College London, 1998.
Distinctions

Award

2014 Best oral communication

Other distinction

1994 PhD scholarship