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Filomena Adega is Assistant Professor in Genetics at the Department of Genetics and Biotechnology (DGB) of the University of Trás-os-Montes and Alto Douro since 2019, the current Coordinator of the Genetics4U Laboratory at UTAD and an Integrated Researcher member of the Biosystems and Integrative Sciences Institute, BioISI-Pólo UTAD, in the CytoGenomics Lab. Filomena has a graduation in Animal Sciences (1998) and a PhD in Genetics (2006). Her academic activity started in 1997, as monitor/collaborator at DGB, and she has been teaching in several curricular units in Genetics and Molecular cytogenetics, Animal in vitro cell culture, Cell imaging, Cell biology, Human genetics, Molecular Evolution, etc, along the years, where she contributed to the higher education of hundreds of students in her areas of expertise. Between 2013 and 2019 she was an Invited Assistant Professor at DGB. Currently she is the Director of the Master in Biotechnology for Health Sciences, Vice-director of the PhD programme in Comparative Molecular Genetics and Vogal of the 1st cycle in Biomedical Sciences at UTAD. Filomena has supervised or co-supervised undergraduate students (38 completed), master's (17 completed and 4 in progress) and PhD (7 completed, 1 in progress) that are now following their professional/research path, thus greatly contributing to the increase of highly prepared and specialized human resources. It was also around 1998 that she started developing her research activity with a research fellow grant in an I&D project, followed by an FCT PhD grant in her area of choice, Comparative Chromosomics and Genome Evolution. Later she earned a post-doc FCT grant and afterwards she was hired as Assistant Researcher for the Centre for Genomics and Biotechnology, Associated Laboratory Institute of Biotechnology and Bioengineering (CGB-UTAD/IBB), under the FCT National Scientific and Technological System - Science 2007 Programme, in Animal Genomics (2008-2013). Regarding this scientific activity, Filomena has indicators demonstrated since 1999, having already published 51 scientific papers in journals with scientific arbitration and indexed in the Scopus source, 2 book chapters, numerous abstracts in Scopus scientific journals and more than 270 new sequences in GenBank (NCBI). These are mainly in the areas of Comparative Genomics, Chromosome Architectures, Establishment of cellular models for oncogenomics, Satellite DNA, non-coding RNA, the Mobilome and the way it acts on Genome evolution both structurally and functionally but also how it causes disease, using different cell models and organisms, such as the Chiroptera. During the years, she has interacted with more than 150 collaborators in co-authoring scientific papers and research projects; actively participated as researcher in 13 projects and regularly revised manuscripts for different scientific journals. This is clear evidence of her contribution to the advance of knowledge, not only at the scientific community level, but also to the society in general. Filomena is responsible for the laser microdissection station and co-responsible for the in vitro animal cell culture facility and the CytoGenomics Lab confocal microscopy unit. In 2020 she was one of the founders of the UTAD's COVID-19 Testing Centre that voluntarily molecularly diagnosed more than 56K SARS-CoV-2 samples during the pandemics. This team effort was vital in the control of the pandemics in the North of Portugal and the proof that science serves the communities at a multitude of levels. Recently she integrated the group of three Researchers that founded the Genetics4U Lab, a multidisciplinary genetics service unit of UTAD serving the academia and the community in general with fundamental and applied research and specialized diagnosis.
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Identification

Personal identification

Full name
MARIA FILOMENA LOPES ADEGA

Citation names

  • Adega, Filomena

Author identifiers

Ciência ID
2A15-8974-0A75
ORCID iD
0000-0001-5646-5534
Google Scholar ID
dyaLW-QAAAAJ
Researcher Id
J-2875-2013
Scopus Author Id
6508379750

Email addresses

  • filadega@utad.pt (Professional)

Telephones

Telephone
  • 259350906 Ext.: 4906 (Professional)

Addresses

  • Complexo Laboratorial, sala A0.08, A1.11, 5001-801, Vila Real, Vila Real, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Evolutionary Biology
  • Natural sciences - Biological Sciences - Biodiversity Conservation

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Proficiency (C2) Proficiency (C2)
Portuguese (Mother tongue)
Spanish; Castilian Advanced (C1) Advanced (C1) Intermediate (B1) Proficiency (C2) Proficiency (C2)
French Elementary (A2) Elementary (A2) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2006/09/29
Concluded
 Genetics, Biological Sciences (Doutoramento)
Major in Genetics
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
"Physical organization in Cetartiodactyla. Modes of chromosomes and karyotypes evolution" (THESIS/DISSERTATION)
 Approved with distinction and honours
1998/02
Concluded
 Animal Science (Licenciatura)
Major in Não Aplicável
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências Agrárias e Veterinárias, Portugal
"Reação fisiológica e celular de duas estirpes de murganho perante a inflamação" (THESIS/DISSERTATION)
 15/20 values
Affiliation

Science

Category
Host institution 		Employer
2015/11/01 - Current Principal Investigator (Research) Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas Polo UTAD, Portugal
Universidade de Trás-os-Montes e Alto Douro, Portugal
2008 - 2013 Auxiliary Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Trás-os-Montes e Alto Douro, Portugal
2007 - 2008 Postdoc (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Trás-os-Montes e Alto Douro, Portugal
2001 - 2005 Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Trás-os-Montes e Alto Douro, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2019/10/04 - Current Assistant Professor (University Teacher) Universidade de Trás-os-Montes e Alto Douro, Portugal
Universidade de Trás-os-Montes e Alto Douro, Portugal
2013/10/01 - 2019/02/28 Invited Assistant Professor (University Teacher) Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
Universidade de Trás-os-Montes e Alto Douro, Portugal
1997/10 - 2006 Tutor (University Teacher) Universidade de Trás-os-Montes e Alto Douro, Portugal
Universidade de Trás-os-Montes e Alto Douro, Portugal

Positions / Appointments

Category
Host institution 		Employer
2024 - Current Organic Unit President Universidade de Trás-os-Montes e Alto Douro, Portugal
Universidade de Trás-os-Montes e Alto Douro, Portugal

Others

Category
Host institution 		Employer
2021/12/21 - Current Coordinator of the Genetics4U Lab Universidade de Trás-os-Montes e Alto Douro, Portugal
Laboratório Genetics4U, Portugal
Projects

Grant

Designation Funders
2021/01/01 - 2021/12/31 How the mobilome shapes genomes: a journey across bat species from the North of Portugal
2021.07537.BD
Supervisor
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Cancelled
2014 - 2018 What is the impact of the cattle chromosome polymorphism Rb t(1;29) in Bovini genome biodiversity and functionality?
SFRH/BD/98122/2013
Supervisor
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2013 - 2017 How satellite DNA comes into play in genomes? A Rodentia cell model approach
SFRH/BD/80808/2011
Supervisor
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2012 - 2016 Molecular and Functional Characterization of a satellite non-coding RNA -FA-SAT- a key player of cycling cells
SFRH/BD/80446/2011
Supervisor
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2009 - 2013 Molecular microevolution in cat mammary lines: Genomic and Cytogenomics cell models
SFRH/BD/48392/2008
Supervisor
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2008 - 2012 The Rattus norvegicus cell model: an integrated analysis of chromosome architecture, genes and satellite non coding sequences
SFRH/BD/41576/2007
Supervisor
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2008 - 2012 Repetitive DNA Sequences in Rodentia Genomes. Its involvement in chromosome architecture reshuffling and in genome functionality
SFRH/BD/41574/2007
Supervisor
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2006 - 2010 Karyotype restructuring in Rodentia: from Evolution to Cancer
SFRH/BD/25813/2005
Supervisor
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2007/01/01 - 2008/02/29 Chromosome bar-codes for rat/mouse. Application to the resolution of complex karyotypes of tumor cell lines
SFRH/BPD/32661/2006
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2017 - Current LungCARD
H2020-MSCA-RISE-2016
Researcher
Horizon 2020 European Innovation Council Fast Track to Innovation
Concluded
2016 - Current ENOEXEL – From vineyard to wine: targeting grape and wine excellency
NORTE-07-0124-FEDER-000032
Researcher
Universidade de Trás-os-Montes e Alto Douro, Portugal
Concluded
2024 - 2026 North+Health Digital Transition and Innovation in Health Education - More Digital Impulse | Reform and Modernization of Medicine
RE-C06-i07
Researcher
Ongoing
2021/03/29 - 2024/03/28 Trunk-BioCode- Diagnostic platforms applied to Trunk Diseases in Grapevine
PTDC/BAA-DIG/1079/2020
Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal

FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal

Universidade de Lisboa Instituto Superior de Agronomia, Portugal

Consejo Superior de Investigaciones Científicas, Spain

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/09/01 - 2023/06/30 Test, Test, Test: upscalling of SARS-CoV-2 molecular diagnosis at the Testing Center COVID-19 UTAD
72537
Researcher
Centro de Testagem COVID-19, UTAD, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2021/10/04 - 2022/07/31 PulmaGENE: Genetic blood analysis to guide therapy of patients with non-small cell lung cancer (NSCLC)
NORTE-01-0247-FEDER033533
Stab Vida Investigação e Serviços em Ciências Biológicas Lda, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal
European Regional Development Fund
Concluded
2020/08/01 - 2021/01/31 On-chip testing of SARS-CoV-2 (SARSChip)
SARSChip
Researcher
INESC Microsistemas e Nanotecnologias, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2020/05/01 - 2020/07/31 Cdots Biosensing COVID19
041_596518523
Researcher
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/01 - 2019/12 Molecular evaluation of HER2 and Topoisomerases in feline mammary carcinoma - Developing rational stratagies for effective diagnosis and cancer chemoimmunotherapy
grant.Provided by PTCRIS: 142267
FCT-PTDC/CVT-EPI/3638/2014
FCT-PTDC/CVT-EPI/3638/2014
Researcher
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2018/02 - 2018/12 A cell model to study UV-B effect in Vitis vinifera L.
N/A
Researcher
Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
 Biosystems & Integrative Sciences Institute (Lisboa, Portugal)
Concluded
2011 - 2011 Projeto Estratégico LA 23
PEst-OE/EQB/LA0023/2011
Researcher
Instituto de Biotecnologia e Bioengenharia, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2005/03 - 2008/06 Comparative Chromosome Maps for Rodent Species Placental Mammalian Chromosome Evolution, Chromosome Bar-Codes and Genomic Functional aspects
grant.Provided by PTCRIS: 58541
FCT POCI/BIABCM/ 58541/2004
Researcher
Universidade de Trás-os-Montes e Alto Douro, Portugal
 Fundação para a Ciência e a Tecnologia
2005 - 2006 System of Confocal Microscopy and Chromosomes and Cell Sorting
REEQ/1156/BIO/2005
Researcher
National Science Foundation
Concluded
1999 - 2001 Estudos Evolutivos de Citogenética Molecular na família Bovidae
PRAXIS/P/BIA/11285/1998
POCTI/P/BIA/11285/2001
POCTI/P/BIA/11285/2001
Research Fellow
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Filomena Adega. "Atlas of mammalian chromosomes". In Atlas of mammalian chromosomes, edited by Alexander S. Graphodatsky, Polina L. Perelman, Stephen J O’Brien. Hoboken, NJ, United States: John Wiley & Sons, Inc, 2020, 2020.
    Published
  2. Mendes-da-Silva, Ana; Adega, Filomena; Chaves, Raquel. "Importance of Fluorescent In Situ Hybridization in Rodent Tumors". In Technical Aspects of Toxicological Immunohistochemistry, 21-49. Springer New York, 2016.
    10.1007/978-1-4939-1516-3_3
  3. Adega, Filomena. "The Importance of Cancer Cell Lines as in vitro Models in Cancer Methylome Analysis and Anticancer Drugs Testing". {InTech, 2013.
    Published • 10.5772/53110
Conference abstract
  1. Marisa Fonseca-Carvalho; Ferreira, Daniela; Lopes, Mariana; Lucas, Diogo; Gabriela Verissímo; Adega, Filomena; Louzada, Sandra; Chaves, Raquel. "Preliminary data about FA-SAT ncRNA function in Mitosis". Paper presented in III International Meeting of the Portuguese Society of Genetics, Évora, 2022.
    Published
  2. Marisa Fonseca-Carvalho; Ferreira, Daniela; Lopes, Mariana; Lucas, Diogo; Gabriela Verissímo; Adega, Filomena; Louzada, Sandra; Chaves, Raquel. "FA-SAT molecular and cellular characterization in human cancer cells". Paper presented in XIV Jornadas de Genética e Biotecnologia e IV Jornadas Ibéricas de Genética e Biotecnologia, VILA REAL, 2022.
    Published
  3. Ferreira, Daniela; Lucas, Diogo; Adega, Filomena; Chaves, Raquel. "Disclosing how FA-SAT ncRNA promotes the switch between cell proliferation and apoptosis". Paper presented in EMBO | EMBL Symposium: The Non-Coding Genome, 2021.
    Published
  4. Diogo Lucas; Ferreira, Daniela; Adega, Filomena; Raquel Chaves. "FA-SAT ncRNA transcriptional characterization: can its distribution influence cancer features?". Paper presented in II International Meeting of the Portuguese Society of Genetics, Vila Real, 2021.
    Published
  5. Lucas, Diogo; Ferreira, Daniela; Adega, Filomena; Chaves, Raquel. "Disclosing how FA-SAT ncRNA/PKM2 complex interferes with proliferative and apoptotic pathways and their key players". Paper presented in VI Jornadas da Bioquímica, Porto, 2021.
    Published
  6. Lucas, Diogo; Ferreira, Daniela; Adega, Filomena; Chaves, Raquel. "Inducing the FA-SAT knockdown in human cancer cells - can the P53 status dictate different outcomes?". Paper presented in II Jornadas de Biotecnologia para as Ciências da Saúde, Vila Real, 2021.
    Published
  7. Lucas, Diogo; Ferreira, Daniela; Adega, Filomena; Chaves, Raquel. "Comparing the FA-SAT ncRNA profile in different human cell lines: Is the expression of FA-SAT (dys)regulated in the cell cycle of HeLa cells?". Paper presented in XIII Jornadas de Genética e Biotecnologia/III Jornadas Ibéricas de Genética Y Biotecnología, Vila Real, 2021.
    Published
  8. Ferreira, Daniela; Lucas, Diogo; Adega, Filomena; Chaves, Raquel. "Insights on the molecular mechanism underlying the apoptosis phenotype of FA-SAT ncRNA/PKM2 complex disruption". Paper presented in Jornadas da Ciência-UTAD, Vila Real, 2021.
    Published
  9. Lucas, Diogo; Ferreira, Daniela; Adega, Filomena; Chaves, Raquel. "FA-SAT ncRNA depletion induces apoptosis ¿ is it through p53 mediation?". Paper presented in XII Genetics and Biotechnology Conference / II Genetics and Biotechnology Iberian Conference., VILA REAL, 2020.
    Published
  10. Ferreira, Daniela; Escudeiro, Ana; Anjo, Sandra I.; Manadas, Bruno; Adega, Filomena; Chaves, Raquel. "FA-SAT: doomed to repeat and transcribe! But why?". Paper presented in IX Jornadas de Genética e Biotecnologia, Vila Real, 2017.
    Published
  11. Ferreira, Daniela; Escudeiro, Ana; Chaves, Filipa; Adega, Filomena; Chaves, Raquel. "How the ¿major¿ satellite ncRNA of Felis catus is regulated in cancer?". Paper presented in XXXIX Portuguese Genetics Conference, Braga, 2015.
    Published
  12. Escudeiro, Ana; Ferreira, Daniela; Adega, Filomena; Chaves, Raquel. "RNAs não codificantes - perfis de transcrição e modelação de uma sequência de DNA satélite". Paper presented in V Jornadas de Genética e Biotecnologia, Vila Real, 2013.
    Published
  13. Vieira-da-Silva, A.; Louzada, S.; Paco, A.; Adega, F.; Guedes-Pinto, H.; Chaves, R.. "The patchwork pattern of satDNAs in the constitutive heterochromatin of Peromyscus eremicus: advances from fiber-FISH". 2012.
  14. Meles, S.; Castro, J.; Adega, F.; Chaves, R.. "Preliminary cytogenetic characterization of one CLS-ACI-1 clone: Putative involvement of satDNA and telomeric sequences in genomic instability.". 2012.
  15. Paco, A.; Chaves, R.; Adega, F.. "The partnership of telomeres and constitutive heterochromatin in the remodelling of genomes". 2012.
  16. Louzada, S.; Adega, F.; Chaves, R.; Louzada, Sandra; Adega, Filomena; Chaves, Raquel. "Molecular cytogenetic characterization of a cell clone from a rat fibrosarcoma cell line". 2010.
    Louzada, Sandra; Adega, Filomena; Chaves, Raquel. Molecular cytogenetic characterization of a cell clone from a rat fibrosarcoma cell line, Trabalho apresentado em 19th International Colloquium on Animal Cytogenetics and Gene Mapping, In 19th Internationa
  17. Louzada, S.; Vieira-da-Silva, A.; Adega, F.; Guedes-Pinto, H.; Chaves, R.; Louzada, Sandra; Adega, Filomena; Guedes-Pinto, Henrique; Chaves, Raquel. "Mouse and rat genomes uncover the chromosome restructuring in Peromyscus eremicus (Cricetidae, Rodentia)-Chromosomes 1 and 5 in focus". 2009.
  18. Santos, S.; Borges, A.; Adega, F.; Gaertner, F.; Guedes-Pinto, H.; Chaves, R.; Chaves, Raquel; et al. "Analysis of a Cat Mammary Tumour (multinodular tubulopapillary carcinoma) by Comparative Genomic Hybridization: a case report". 2009.
    Borges, A.; Chaves, Raquel; Santos, Sara; Gärtner, Fátima; Guedes-Pinto, Henrique; Adega, Filomena. Candidate genes for cat mammary tumor: a survey from comparative genomic hybridization analysis, Trabalho apresentado em 19th International Colloquium on A
  19. Adega, F.; Louzada, S.; Vieira-da-Silva, A.; Guedes-Pinto, H.; Kofler, A.; Wienberg, J.; Chaves, R.. "The freewill of evolution in the structuring of Rodentia genomes". 2008.
  20. Meles, S.; Paco, A.; Adega, F.; Guedes-Pinto, H.; Chaves, R.; Meles, Susana; Paço, Ana; et al. "A detailed Constitutive Heterochromatin Map for Praomys tullbergi (Rodentia, Muridae) karyotype". 2008.
  21. Paco, Ana; Adega, Filomena; Guedes-Pinto, Henrique; Volobouev, Vitaly; Chaves, Raquel. "Constitutive heterochromatin characterization of the rodents Peromyscus eremicus, Cricetus cricetus and Praomys tullbergi". 2007.
Conference paper
  1. Adega, Filomena. "Robertsonian translocations are not a single event of centric fusion mechanistic insights driven by the Bovinae rob(1;29) model". Paper presented in European Cytogenomics Conference 2019, Salzburg, 2019.
    Published • 10.1186/s13039-019-0439-z
  2. Liberal, Ângela; Pereira, Carla; Calhelha, Ricardo C.; Abreu, Rui M.V.; Adega, Filomena; Ferreira, Isabel C.F.R.. "Antioxidant and anti-inflammatory properties of red, white and pink globe amaranth hydromethanolic extracts". 2015.
  3. Liberal, Ângela; Pereira, Carla; Adega, Filomena; Barros, Lillian; Ferreira, Isabel C.F.R.. "Tocopherols as bioactive compounds in different cultivars of Gomphrena globosa L.". 2015.
  4. Paço, Ana; Adega, Filomena; Mestrovic, N.; Silva, A.; Plohl, M.; Chaves, Raquel. "Construction of repetitive DNA libraries from the genomes of two hamster species, Phodopus sungorus and Phodopus roborovskii (Cricetinae)". 2011.
  5. Abreu, Rui M.V.; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Adega, Filomena; Chaves, Raquel. "New potential anti-hepatocellular carcinoma (HCC) agents: in vitro evaluation of anti-HCC activity and hepatotoxicity of 6-substituted methyl 3-aminothieno[3,2-b]pyridine-2-carboxylates and QSAR studies". 2011.
  6. Borges, A.; Adega, Filomena; Escudeiro, A.; Chaves, Raquel. "Chromosomal instability in a cat mammary cancer cell line". 2011.
  7. Vieira-da-Silva; Adega, Filomena; Soares, M.; Chaves, Raquel; Guedes-Pinto, Henrique. "Physical location of satellite DNA I family in Peromyscus eremicus (Rodentia, Cricetidae)". 2011.
  8. Vieira-da-Silva; Louzada, Sandra; Adega, Filomena; Guedes-Pinto, Henrique; Chaves, Raquel; Vieira-da-Silva, A.; Paço, Ana; et al. "An orthologous satellite DNA family between Muridae and Cricetidae (Rodentia)". 2010.
    Vieira-da-Silva; Louzada, Sandra; Adega, Filomena; Guedes-Pinto, Henrique; Chaves, Raquel. An orthologous satellite DNA family between Muridae and Cricetidae (Rodentia), Trabalho apresentado em 19th International Colloquium on Animal Cytogenetics and Gene
  9. Abreu, Rui M.V.; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R.; Adega, Filomena; Chaves, Raquel. "Anti-proliferative activity of thieno[3,2-b]pyridine derivatives in tumoral and primary hepatic cell lines.". 2010.
  10. Vieira-da-Silva, A.; Louzada, Sandra; Adega, Filomena; Guedes-Pinto, Henrique; Chaves, Raquel; Louzada, S.; Adega, F.; Guedes-Pinto, H.; Chaves, R.. "Comparative analysis of two Cricetus cricetus chromosomes with Mus musculus and Rattus norvegicus using chromosome painting". 2009.
  11. Adega, Filomena; Vieira-da-Silva, A.; Guedes-Pinto, Henrique; Chaves, Raquel; Adega, F.; da Silva, A. Vieira; Guedes-Pinto, H.; Chaves, R.. "Cytogenetic and molecular analysis of LINE-1 sequences in Tatera gambiana and Acomys sp. Rodents". 2009.
  12. Borges, A.; Santos, Sara; Adega, Filomena; Gärtner, Fátima; Guedes-Pinto, Henrique; Chaves, Raquel; Santos, S.; et al. "New advances in Cat Mammary Tumours: Comparative Genomic Hybridization profiles in a case of tubulopapillary carcinoma". 2009.
  13. Paço, Ana; Adega, Filomena; Guedes-Pinto, Henrique; Chaves, Raquel; Paco, A.; Adega, F.; Guedes-Pinto, H.; Chaves, R.. "Repetitive sequences: a possible source of genome Remodelling". 2009.
  14. Meles, Susana; Adega, Filomena; Guedes-Pinto, Henrique; Chaves, Raquel; Meles, S.; Adega, F.; Guedes-Pinto, H.; Chaves, R.. "Telomeric repeats (TTAGGG)n as footprints of evolutionary chromosome rearrangements". 2009.
  15. Adega, Filomena; Meles, Susana; Guedes-Pinto, Henrique; Wienberg, Johannes; Chaves, Raquel. "Praomys tullbergi genome architecture decoded by the related genomes Mus and Rattus". 2007.
  16. Meles, Susana; Adega, Filomena; Volobouev, V.; Guedes-Pinto, Henrique; Chaves, Raquel. "Praomys tullbergi (Muridae, Rodentia): Karyotype and sex chromosomes evolutionary insight". 2007.
  17. Louzada, Sandra; Vieira-da-Silva, A.; Kubickova, Svatava; Adega, Filomena; Guedes-Pinto, Henrique; Chaves, Raquel; Jiri, J.. "Cricetus cricetus and Peromyscus eremicus (Rodentia, Cricetidae) share common repetitive DNA sequences". 2007.
  18. Paço, Ana; Adega, Filomena; Guedes-Pinto, Henrique; Volobouev, V.; Chaves, Raquel; Louzada, S.; Paço, A.; et al. "Constitutive heterochromatin characterization of the rodents Peromyscus eremicus, Cricetus cricetus (Cricetidae) and Praomys tullbergi (Muridae)". 2007.
    10.1016/j.micron.2008.05.008
  19. Vieira-da-Silva, A.; Louzada, Sandra; Adega, Filomena; Kubickova, Svatava; Guedes-Pinto, Henrique; Jiri, J.; Chaves, Raquel. "X chromosome patchwork in the rodents Cricetus cricetus, Peromyscus eremicus (Cricetidae) and Praomys tulbergi (Muridae)". 2007.
  20. Iannuzzi, L.; Rangel-Figueiredo, M. T.; Di Meo, G. P.; Molteni, L; Perucatti, A.; De Giovanni, A. M.; Chaves, Raquel; et al. "Cytogenetic characterization, frequency and distribution of rob t(1;29) in some Italian and Portuguese cattle breeds". 2004.
  21. Adega, Filomena; Chaves, Raquel; Heslop-Harrison, J. S; Guedes-Pinto, Henrique; Wienberg, Johannes. "Chromosomal and Satellite (1.709 family) DNA analysis in Bovini and Tragelaphini tribes: inferences within the Bovidae family". 2004.
  22. Chaves, Raquel; Adega, Filomena; Heslop-Harrison, John S.; Guedes-Pinto, Henrique; Wienberg, Johannes. "Complex DNA reshuffling in the cattle 1;29 translocation: a two-step model of the dynamic evolution of the 1;29 chromosome". 2004.
  23. Adega, Filomena; Chaves, Raquel; Heslop-Harrison, John S.; Wienberg, Johannes; Guedes-Pinto, Henrique. "New insights into Bovidae satellite III evolutionary history". 2004.
  24. Chaves, Raquel; Adega, Filomena; Heslop-Harrison, John S.; Guedes-Pinto, Henrique; Wienberg, Johannes. "1.709 satellite IV DNA sequences evolution in the Bovini and Tragelaphini tribes". 2003.
  25. Chaves, Raquel; Adega, Filomena; Santos, Sara; Heslop-Harrison, John S.; Guedes-Pinto, Henrique. "Physical distribution of the Ovis aries alpha-satellite sequence in the Bovidae family: Evolutionary considerations". 2001.
  26. Chaves, Raquel; Heslop-Harrison, John S.; Adega, Filomena; Guedes-Pinto, Henrique. "Characterization of the cattle rob (1;29) centromeric heterochromatin by restriction endonuclease digestion and in situ hybridization with cattle satellite I probe". 1999.
  27. Adega, Filomena; Chaves, Raquel; Heslop-Harrison, John S.; Guedes-Pinto, Henrique. "Restriction endonuclease banding-HaeIII and HinfI, and subsequent C-banding on cattle metaphase chromosomes". 1999.
Conference poster
  1. Costa, Sara; Castro, Francisca; Mestre, Verónica; Pereira, Jorge; Escudeiro, Ana; Barros, Paulo; Chaves, Raquel; et al. "A physical map of repetitive elements in the genomes of Iberian Peninsula chiropteran species". Paper presented in IV International Meeting of the Portuguese Society of Genetics, 2023.
  2. Patrícia V. Teixeira; Adega, Filomena; Martins-Lopes, Paula; LUCIO, MARLENE; Carla M. Lopes. Corresponding author: Carla M. Lopes. "Design, optimization, and in vitro therapeutic performance of pH triggered doxorubicin from 2D and 3D lipid nanoassemblies". Paper presented in 12th International Colloids Conference 2023, 2023.
  3. Costa, Sara; Vaz-Pires, Ana; Pereira, Jorge; Mestre, Verónica; Barros, Paulo; Chaves, Raquel; Ray, D; Cabral, João; Adega, Filomena. "Karyotypic evolution of two bat species through a comparative ZOO-FISH". Paper presented in XV Genetics and Biotechnology Conference / V Genetics, 2023.
  4. Gaspar, Maria; Chaves R; Hindrison M; Pereira J; Adega, Filomena. "A phylogenetic and evolutionary analysis of transposable elements in the wolf (Canis lupus, Canidae, Carnivora) genome". Paper presented in XV Genetics and Biotechnology Conference / V Iberian Genetics and Biotechnology Conference, 2023.
  5. Patrícia V. Teixeira; Carla M. Lopes; Adega, Filomena; Martins-Lopes, Paula; LUCIO, MARLENE. Corresponding author: LUCIO, MARLENE. "Hybrid nanosystems for cancer therapy". Paper presented in RICI 9 - 9th Iberian Meeting on Colloids and Interfaces, 2022.
  6. Gatinho, Patrícia; Chaves, Raquel; Adega, Filomena; Fernandes, José Ramiro Afonso; Martins-Lopes P.. "Preliminary tests of a piezoelectric biosensor for direct sample detection". Paper presented in III International Meeting of the Portuguese Society of Genetics, 2022.
  7. Ala, Maria Inês; Castro, Francisca; Ribeiro, Diogo; Ferreira, Daniela; Escudeiro, Ana; Adega, Filomena; Adega, Filomena. "Combination of cytogenetics, genomics and bioinformatics methodologies for the detection and study of complex chromosome alterations". Paper presented in XIV Jornadas de Genética e Biotecnologia e IV Jornadas Ibéricas de Genética e Biotecnologia, 2022.
  8. Costa, Sara; Adega, Filomena. "History of the evolution of the human genome". Paper presented in XIV Genetics and Biotechnology Conference / IV Genetics and Biotechnology Iberian Conference, 2022.
  9. Adega, Filomena; Mestre, Verónica F.; Barros P; Cabral dos Santos, Joao; faria S; Chaves r; Ray D. "The karyotype of Myotis daubentonii: A first step towards chromosome evolution of the species". Paper presented in VIII JORNADAS SECEMU, 2021.
  10. Cunha, Catarina; Pinto, Albano; Chaves, Raquel; Adega, Filomena. "Transposable elements dynamics in the human genome". Paper presented in XIII Genetics and Biotechnology Conference / III Genetics and Biotechnology Iberian Conference, 2021.
  11. Gatinho, Patrícia; Chaves, Raquel; Adega, Filomena; Fernandes, José Ramiro Afonso; Martins-Lopes P.. "The Role of Biosensors in Pulmonary Cancer Diagnosis". Paper presented in XIV Genetics and Biotechnology Conference / IV Genetics and Biotechnology Iberian Conference, 2021.
  12. Luís, Diogo P.; Adega, Filomena; Abreu, Rui M.V.. "Tyrosinase as a protein target for dermatological treatment". Paper presented in Natural Products Application: Health, Cosmetic and Food online edition, 2021.
  13. Pinheiral, José P.L; Adega, Filomena; Abreu, Rui M.V.. "In silico study of a library of flavonoids as potential collagenase inhibitors". Paper presented in Natural products application: Health, Cosmetic and Food, 2021.
  14. Sampaio, Luís C.M.; Adega, Filomena; Abreu, Rui M.V.. "Elastase and its potential as target protein for bioactive compounds". Paper presented in Natural Products Application: Health, Cosmetic and Food online edition, 2021.
  15. Lucas, Diogo; Ferreira, Daniela; Adega, Filomena; Chaves, Raquel. "Cellular characterization of FA-SAT ncRNA in cancer cells". Paper presented in XXIII Encontro Nacional de Estudantes de Biologia (ENEB), 2021.
  16. Pinto, Albano; Cunha, Catarina; Chaves, Raquel; Adega, Filomena. "The potential involvement of transposable elements in spinal muscular atrophy, a neuromuscular disease". Paper presented in XII Genetics and Biotechnology Conference / II Genetics and Biotechnology Iberian Conference, 2020.
  17. Miranda, Juliana; Ferreira, Daniela; Clemente, Carla; Martins-Lopes, Paula; Adega, Filomena; Chaves, Raquel. "Screening of EGFR mutations in non-small cell lung cancer patients in liquid biopsies". Paper presented in XII Genetics and Biotechnology Conference/II Genetics and Biotechnology Iberian Conference, 2020.
  18. Ferreira, Daniela; Miranda, Juliana; Martins-Lopes, Paula; Adega, Filomena; Chaves, Raquel. "Preliminary approach for the analysis of EGFR mutations in cell-free DNA from non-small cell lung cancer patients.". Paper presented in International Meeting Of The Portuguese Society Of Genetics, 2020.
  19. Lopes, Mariana; Escudeiro, Ana; Adega, Filomena; Gama-Carvalho, Margarida; Chaves, Raquel. "Mapping Human Satellite I, an intervenient in Robertsonian Translocations". 2020.
  20. Santos, Soraia; Luís, Diogo; Abreu, Rui M.V.; Adega, Filomena. Corresponding author: Santos, Soraia. "Molecular docking: applications in drug discovery". Paper presented in XII Jornadas de Genética e Biotecnologia/ II Jornadas Ibéricas de Genética y Biotecnología, 2020.
  21. Ferreira, Daniela; Barrias, Sara; Adega, Filomena; Fernandes, D; Clemente, Carla; Martins-Lopes, Paula; Chaves, Raquel. "PulmaGENE ¿ Análise de biomarcadores preditivos em biopsias líquidas de pacientes com carcinoma do pulmão de não pequenas células". Paper presented in 1º Encontro Nacional De Jovens Investigadores Em Oncologia, 2019.
  22. Lopes, Mariana; Escudeiro, Ana; Adega, Filomena; Sandra Louzada; Dias, Ricardo; Gama-Carvalho, Margarida; Chaves, Raquel. "Filling the gaps: disclosure of the human centromere in Robertsonian translocated chromosomes using Nanopore sequencing". Paper presented in GenomePT symposium, 2019.
  23. Ferreira, Daniela; Escudeiro, Ana; Adega, Filomena; Anjo, Sandra I.; Manadas, Bruno; Chaves, Raquel. "FA-SAT ncRNA forms a ribonucleoprotein complex with PKM2". Paper presented in VIII National RNA meeting: ptRNA2019, 2019.
  24. Lopes, Mariana; Escudeiro, Ana; Adega, Filomena; Chaves, Raquel. "Characterization of Sus scrofa painting probes obtained by FACS for karyotype analysis". Paper presented in UTAD Biochemestry Conference/ I Week of Science and Citizenship, 2018.
  25. Ferreira, Daniela; Mendes-da-Silva, A.; Meles, Susana; Adega, Filomena; Chaves, Raquel. "Challenges and Perspectives in the Research of Satellite DNA Sequences ¿ Assembling FA-SAT in Carnivora Genomes". Paper presented in Workshop - Innovation in Genomic Technologies, 2018.
  26. Martins, Bárbara; Ferreira, Daniela; Soares, Maria; Adega, Filomena; Ferreira, Fernando; Chaves, Raquel. "Disclosing the PKM2 expression profile in cat mammary tumours". Paper presented in IX Jornadas de Genética e Biotecnologia, 2017.
  27. Ferreira, Daniela; Chaves, Filipa; Borges, Ana; Escudeiro, Ana; Adega, Filomena; Chaves, Raquel. "The major Satellite Non-Coding Sequence of Felis catus: its putative involvement in tumorigenesis". Paper presented in EMBO/EMBL Symposia: The Non-Coding Genome, 2015.
  28. Ferreira, Daniela; Chaves, Filipa; Escudeiro, Ana; Adega, Filomena; Chaves, Raquel. "Satellite DNA transcription dysregulation in a cat tumor cell line: What the implications in tumorigenesis?". Paper presented in VII Jornadas de Genética e Biotecnologia, 2015.
  29. Escudeiro, Ana; Ferreira, Daniela; Adega, Filomena; Chaves, Raquel. "The same sequence in a different chromosomal context: What are the implications?". Paper presented in VI Jornadas nacionais de Genética e Biotecnologia, 2014.
Journal article
  1. Gonçalves, Helena M.R.; Neves, Susana A.F.; Rodriguez, Sabela; Pereira, Rui F.P.; Vilarinho, Rui; Moniz, Tânia; Rangel, Maria; et al. "Biocompatible cdots dual role: Nanophotosensitizers for hypoxic photodynamic therapy and scavenging nanozyme biosensing". Biosensors and Bioelectronics: X 19 (2024): 100499. https://doi.org/10.1016/j.biosx.2024.100499.
    10.1016/j.biosx.2024.100499
  2. Catarina Lino; Sara Barrias; Raquel Chaves; Filomena Adega; José Ramiro Fernandes; Paula Martins-Lopes. "Development of a QCM-based biosensor for the detection of non-small cell lung cancer biomarkers in liquid biopsies". Talanta (2023): https://doi.org/10.1016/j.talanta.2023.124624.
    10.1016/j.talanta.2023.124624
  3. Patrícia Teixeira; Eduarda Barbosa Fernandes (grantee); Soares, Telma B.; Adega, Filomena; Carla M. Lopes; LUCIO, MARLENE. Corresponding author: LUCIO, MARLENE. "Natural Compounds: Co-Delivery Strategies with Chemotherapeutic Agents or Nucleic Acids Using Lipid-Based Nanocarriers". Pharmaceutics 15 4 (2023): 1317. https://doi.org/10.3390/pharmaceutics15041317.
    Published • 10.3390/pharmaceutics15041317
  4. Teixeira, Patrícia V.; Adega, Filomena; Martins-Lopes, Paula; Machado, Raul; Lopes, Carla M.; Lúcio, Marlene. "pH-Responsive Hybrid Nanoassemblies for Cancer Treatment: Formulation Development, Optimization, and In Vitro Therapeutic Performance". Pharmaceutics 15 2 (2023): 326. http://dx.doi.org/10.3390/pharmaceutics15020326.
    10.3390/pharmaceutics15020326
  5. Ferreira, Daniela; Soares, Maria; Correia, Jorge; Adega, Filomena; Ferreira, Fernando; Chaves, Raquel. "Satellite Noncoding RNAs (ncRNA) as Cancer Biomarkers? New Insights from FA-SAT ncRNA Molecular and Clinical Profiles in Feline Mammary Tumors". OMICS: A Journal of Integrative Biology 26 11 (2022): 622-632. http://dx.doi.org/10.1089/omi.2022.0114.
    10.1089/omi.2022.0114
  6. Pinto, Albano; Cunha, Catarina; Chaves, Raquel; Butchbach, Matthew E. R.; Adega, Filomena. "Comprehensive In Silico Analysis of Retrotransposon Insertions within the Survival Motor Neuron Genes Involved in Spinal Muscular Atrophy". Biology 11 6 (2022): 824. http://dx.doi.org/10.3390/biology11060824.
    10.3390/biology11060824
  7. Lino, C.; Barrias, S.; Chaves, R.; Adega, F.; Martins-Lopes, P.; Fernandes, J.R.. "Biosensors as diagnostic tools in clinical applications". Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1877 3 (2022): 188726. http://dx.doi.org/10.1016/j.bbcan.2022.188726.
    10.1016/j.bbcan.2022.188726
  8. A. Escudeiro; F. Adega; T. J. Robinson; J. S. Heslop-Harrison; R. Chaves. "Analysis of the Robertsonian (1;29) fusion in Bovinae reveals a common mechanism: insights into its clinical occurrence and chromosomal evolution". Chromosome Research (2021): https://doi.org/10.1007/s10577-021-09667-0.
    10.1007/s10577-021-09667-0
  9. Ferreira, Daniela; Miranda, Juliana; Martins-Lopes, Paula; Adega, Filomena; Chaves, Raquel. "Future Perspectives in Detecting EGFR and ALK Gene Alterations in Liquid Biopsies of Patients with NSCLC". International Journal of Molecular Sciences 22 8 (2021): 3815. http://dx.doi.org/10.3390/ijms22083815.
    10.3390/ijms22083815
  10. Louzada, Sandra; Lopes, Mariana; Ferreira, Daniela; Adega, Filomena; Escudeiro, Ana; Gama-Carvalho, Margarida; Chaves, Raquel. "Decoding the Role of Satellite DNA in Genome Architecture and Plasticity—An Evolutionary and Clinical Affair". Genes 11 1 (2020): 72. http://dx.doi.org/10.3390/genes11010072.
    10.3390/genes11010072
  11. Ferreira, Daniela; Martins, Bárbara; Soares, Maria; Correia, Jorge; Adega, Filomena; Ferreira, Fernando; Chaves, Raquel. "Gene expression association study in feline mammary carcinomas". PLOS ONE 14 8 (2019): e0221776. http://dx.doi.org/10.1371/journal.pone.0221776.
    10.1371/journal.pone.0221776
  12. Ferreira, Daniela; Escudeiro, Ana; Adega, Filomena; Anjo, Sandra I.; Manadas, Bruno; Chaves, Raquel. "FA-SAT ncRNA interacts with PKM2 protein: depletion of this complex induces a switch from cell proliferation to apoptosis". Cellular and Molecular Life Sciences (2019): http://dx.doi.org/10.1007/s00018-019-03234-x.
    10.1007/s00018-019-03234-x
  13. Adega, Filomena. "Assessment of ERRB2 and TOP2a gene status and expression profile in feline mammary tumors: findings and guidelines.". Aging US (2019): https://doi.org/10.18632/aging.102079.
    10.18632/aging.102079
  14. A. Escudeiro; D. Ferreira; A. Mendes-da-Silva; J. S. Heslop-Harrison; F. Adega; R. Chaves. "Bovine satellite DNAs – a history of the evolution of complexity and its impact in the Bovidae family". The European Zoological Journal 86 1 (2019): 20-37. https://doi.org/10.1080/24750263.2018.1558294.
    10.1080/24750263.2018.1558294
  15. Ferreira, D.; Escudeiro, A.; Adega, F.; Chaves, R.. "DNA methylation patterns of a satellite non-coding sequence – FA-SAT in cancer cells: Its expression cannot be explained solely by DNA methylation". Frontiers in Genetics 10 FEB (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85065837935&partnerID=MN8TOARS.
    10.3389/fgene.2019.00101
  16. Escudeiro, A.; Adega, F.; Robinson, T.J.; Heslop-Harrison, J.S.; Chaves, R.. "Conservation, divergence, and functions of centromeric satellite DNA families in the bovidae". Genome Biology and Evolution 11 4 (2019): 1152-1165. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065052429&partnerID=MN8TOARS.
    10.1093/gbe/evz061
  17. Filomena Adega; Raquel Matoso Silva; Helena J. Kjöllerström; Paul Vercammen; Terje Raudsepp; Maria J. Collares-Pereira; Carlos Fernandes; Maria do Mar Oom; Raquel Chaves. "Comparative Chromosome Painting in Genets (Carnivora, Viverridae, Genetta), the Only Known Feliforms with a Highly Rearranged Karyotype". Cytogenetic and Genome Research (2018): https://doi.org/10.1159%2F000491868.
    10.1159/000491868
  18. Raquel Chaves; Daniela Ferreira; Ana Mendes-da-Silva; Susana Meles; Filomena Adega. "FA-SAT Is an Old Satellite DNA Frozen in Several Bilateria Genomes". Genome Biology and Evolution 9 11 (2017): 3073-3087. https://doi.org/10.1093%2Fgbe%2Fevx212.
    10.1093/gbe/evx212
  19. Filomena Adega; Ana Borges; Raquel Chaves. "Cat Mammary Tumors: Genetic Models for the Human Counterpart". Veterinary Sciences 3 3 (2016): 17-17. https://doi.org/10.3390%2Fvetsci3030017.
    10.3390/vetsci3030017
  20. A. VIEIRA-DA-SILVA; F. ADEGA; H. GUEDES-PINTO; R. CHAVES. "LINE-1 distribution in six rodent genomes follow a species-specific pattern". Journal of Genetics 95 1 (2016): 21-33. https://doi.org/10.1007%2Fs12041-015-0595-9.
    10.1007/s12041-015-0595-9
  21. Ana Borges; Filomena Adega; Raquel Chaves. "Establishment and characterization of a new feline mammary cancer cell line, FkMTp". Cytotechnology 68 4 (2016): 1529-1543. https://doi.org/10.1007%2Fs10616-015-9912-7.
    10.1007/s10616-015-9912-7
  22. Liberal, Ângela; Calhelha, Ricardo C.; Pereira, Carla; Adega, Filomena; Barros, Lillian; Dueñas, Montserrat; Santos-Buelga, Celestino; Abreu, Rui M.V.; Ferreira, Isabel C.F.R.. "A comparison of the bioactivity and phytochemical profile of three different cultivars of globe amaranth: red, white, and pink". The phytochemical profiles and bioactivities of red, white and pink globe amaranth (Gomphrena haageana K., Gomphrena globosa var. albiflora and Gomphrena sp., respectively), much less studied than the purple species (G. globosa L.), were compared. The chemical characterization of the samples included the analysis of macronutrients and individual profiles of sugars, organic acids, fatty acids, toco (2016): http://hdl.handle.net/10198/13347.
    10.1039/c5fo01342a
  23. Adega, Filomena. "Classical and molecular cytogenetics of the panther genet Genetta maculata (Mammalia, Carnivora, Viverridae)". Cytogenetic and Genome Research 149 4 (2016): 274-281. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000390672400007&KeyUID=WOS:000390672400007.
    10.1159/000450627
  24. Sandra Louzada; Ana Vieira-da-Silva; Ana Mendes-da-Silva; Svatava Kubickova; Jiri Rubes; Filomena Adega; Raquel Chaves. "A novel satellite DNA sequence in the Peromyscus genome (PMSat): Evolution via copy number fluctuation". Molecular Phylogenetics and Evolution 92 (2015): 193-203. https://doi.org/10.1016%2Fj.ympev.2015.06.008.
    10.1016/j.ympev.2015.06.008
  25. Daniela Ferreira; Susana Meles; Ana Escudeiro; Ana Mendes-da-Silva; Filomena Adega; Raquel Chaves. "Satellite non-coding RNAs: the emerging players in cells, cellular pathways and cancer". Chromosome Research 23 3 (2015): 479-493. https://doi.org/10.1007%2Fs10577-015-9482-8.
    10.1007/s10577-015-9482-8
  26. Ana Paço; Filomena Adega; Nevenka Meštrovic; Miroslav Plohl; Raquel Chaves. "The puzzling character of repetitive DNA in Phodopus genomes (Cricetidae, Rodentia)". Chromosome Research 23 3 (2015): 427-440. https://doi.org/10.1007%2Fs10577-015-9481-9.
    10.1007/s10577-015-9481-9
  27. Adega, Filomena. "Cytogenetic assessment of the rat cell line CLS-ACI-1. An in vitro cell model for Mycn overexpression". Cytogenetic and Genome Research 146 4 (2015): 285-295. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000368071900005&KeyUID=WOS:000368071900005.
    10.1159/000441374
  28. Ana Vieira-da-Silva; Sandra Louzada; Filomena Adega; Raquel Chaves. "A High-Resolution Comparative Chromosome Map of Cricetus cricetus and Peromyscus eremicus Reveals the Involvement of Constitutive Heterochromatin in Breakpoint Regions". Cytogenetic and Genome Research 145 1 (2015): 59-67. https://doi.org/10.1159%2F000381840.
    10.1159/000381840
  29. Adega, Filomena; A. Paco; F. Adega; N. Me trovi ; M. Plohl; R. Chaves. "Evolutionary story of a satellite DNA from Phodopus sungorus (Rodentia, Cricetidae).". Genome biology and evolution 6 10 (2014): 2944-2955. http://gbe.oxfordjournals.org/content/6/10/2944.long.
    doi: 10.1093/gbe/evu233
  30. Paço, A.; Adega, F.; Chaves, R.. "LINE-1 retrotransposons: from 'parasite' sequences to functional elements". Journal of Applied Genetics (2014): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000348119600015&KeyUID=WOS:000348119600015.
    10.1007/s13353-014-0241-x
  31. Paço, A.; Chaves, R.; Vieira-da-Silva, A.; Adega, F.. "The involvement of repetitive sequences in the remodelling of karyotypes: The Phodopus genomes (Rodentia, Cricetidae)". Micron 46 (2013): 27-34. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875404520&partnerID=MN8TOARS.
    10.1016/j.micron.2012.11.010
  32. Louzada, Sandra; Adega, Filomena; Chaves, Raquel. "Defining the sister rat mammary tumor cell lines HH-16 cl.2/1 and HH-16.cl.4 as an in vitro cell model for Erbb2". Cancer cell lines have been shown to be reliable tools in genetic studies of breast cancer, and the characterization of these lines indicates that they are good models for studying the biological mechanisms underlying this disease. Here, we describe the molecular cytogenetic/genetic characterization of two sister rat mammary tumor cell lines, HH-16 cl.2/1 and HH-16.cl.4, for the first time. Molecu 7 1 (2012): 206-220. http://hdl.handle.net/10348/1598.
    10.1371/journal.pone.0029923
  33. Chaves, Raquel; Louzada, Sandra; Meles, Susana; Wienberg, Johannes; Adega, Filomena. "Praomys tullbergi (Muridae, Rodentia) genome architecture decoded by comparative chromosome painting with Mus and Rattus". Chromosome Research 20 6 (2012): 673-683. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000310318700003&KeyUID=WOS:000310318700003.
    10.1007/s10577-012-9304-1
  34. Badenhorst, Daleen; Dobigny, Gauthier; Adega, Filomena; Chaves, Raquel; O'Brien, Patricia C. M.; Ferguson-Smith, Malcolm A.; Waters, Paul D.; Robinson, Terence J.. "Chromosomal evolution in Rattini (Muridae, Rodentia)". Chromosome Research 19 6 (2011): 709-727. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000300089200002&KeyUID=WOS:000300089200002.
    10.1007/s10577-011-9227-2
  35. Abreu, R.M.V.; Ferreira, I.C.F.R.; Calhelha, R.C.; Lima, R.T.; Vasconcelos, M.H.; Adega, F.; Chaves, R.; Queiroz, M.-J.R.P.. "Anti-hepatocellular carcinoma activity using human HepG2 cells and hepatotoxicity of 6-substituted methyl 3-aminothieno[3,2-b]pyridine-2- carboxylate derivatives: In vitro evaluation, cell cycle analysis and QSAR studies". European Journal of Medicinal Chemistry 46 12 (2011): 5800-5806. http://www.scopus.com/inward/record.url?eid=2-s2.0-80955172000&partnerID=MN8TOARS.
    10.1016/j.ejmech.2011.09.029
  36. Adega, F.; Guedes-Pinto, H.; Chaves, R.; Adega, Filomena; Guedes-Pinto, Henrique; Chaves, Raquel. "Satellite DNA in the Karyotype Evolution of Domestic - Animals Clinical Considerations". Cytogenetic and Genome Research 126 1-2 (2009): 12-20. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000272605100003&KeyUID=WOS:000272605100003.
    10.1159/000245903
  37. Paço, Ana; Adega, Filomena; Guedes-Pinto, Henrique; Chaves, Raquel. "Hidden heterochromatin: characterization in the Rodentia species Cricetus cricetus, Peromyscus eremicus (Cricetidae) and Praomys tullbergi (Muridae)". Genetics and Molecular Biology 32 1 (2009): 56-68. http://dx.doi.org/10.1590/s1415-47572009000100009.
    Published • 10.1590/s1415-47572009000100009
  38. Louzada, Sandra; Paço, Ana; Kubickova, Svatava; Adega, Filomena; Guedes-Pinto, Henrique; Rubes, Jiri; Chaves, Raquel. "Different evolutionary trails in the related genomes Cricetus cricetus and Peromyscus eremicus (Rodentia, Cricetidae) uncovered by orthologous satellite DNA repositioning". Micron 39 8 (2008): 1149-1155. http://dx.doi.org/10.1016/j.micron.2008.05.008.
    Published • 10.1016/j.micron.2008.05.008
  39. Payan-Carreira, R.; Pires, M.A.; Quaresma, M.; Chaves, Raquel; Adega, Filomena; Guedes-Pinto, Henrique; Colaço, B.; et al. "A complex intersex condition in a Holstein calf". Animal Reproduction Science 103 1-2 (2008): 154-163. http://hdl.handle.net/10348/1642.
    10.1016/j.anireprosci.2007.04.013
  40. Adega, Filomena; Chaves, Raquel; Guedes-Pinto, Henrique. "Suiformes orthologous satellite DNAs as a hallmark of Pecari tajacu and Tayassu pecari (Tayassuidae) evolutionary rearrangements". Micron 39 8 (2008): 1281-1287. http://hdl.handle.net/10348/1610.
    10.1016/j.micron.2008.03.004
  41. Meles, Susana; Adega, Filomena; Guedes-Pinto, Henrique; Chaves, Raquel. "The karyotype and sex chromosomes of Praomys tullbergi (Muridae, Rodentia): A detailed characterization". Micron 39 5 (2008): 559-568. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000257532400007&KeyUID=WOS:000257532400007.
    10.1016/j.micron.2007.07.002
  42. Adega, Filomena; Chaves, Raquel; Guedes-Pinto, Henrique; Adega, F.; Chaves, R.; Guedes-Pinto, H.. "Chromosomal evolution and phylogenetic analyses in Tayassu pecari and Pecari tajacu (Tayassuidae): tales from constitutive heterochromatin". Journal of Genetics 86 1 (2007): 19-26. http://hdl.handle.net/10348/1635.
    10.1007/s12041-007-0003-1
  43. Oliveira, P.A.; Adega, F.; Palmeira, C.A.; Chaves, R.M.; Colaço, A.A.; Guedes-Pinto, H.; De La Cruz P, L.F.; et al. "DNA study of bladder papillary tumours chemically induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in Fisher rats". International Journal of Experimental Pathology 88 1 (2007): 39-46. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846460059&partnerID=MN8TOARS.
    10.1111/j.1365-2613.2006.00517.x
  44. Meo, G. P.; Perucatti, A.; Chaves, Raquel; Adega, Filomena; Lorenzi, L.; Molteni, L.; Giovanni, A.; et al. "Cattle rob(1;29) originating from complex chromosome rearrangements as revealed by both banding and FISH-mapping techniques". Chromosome Research 14 6 (2006): 649-655. http://hdl.handle.net/10348/1645.
    10.1007/s10577-006-1074-1
  45. Santos, S.; Chaves, R.; Adega, F.; Bastos, E.; Guedes-Pinto, H.. "Amplification of the major satellite DNA family (FA-SAT) in a cat fibrosarcoma might be related to chromosomal instability". Journal of Heredity 97 2 (2006): 114-118. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644928090&partnerID=MN8TOARS.
    10.1093/jhered/esj016
  46. Adega, F.; Chaves, R.; Kofler, A.; Krausman, P.R.; Masabanda, J.; Wienberg, J.; Guedes-Pinto, H.; et al. "High-resolution comparative chromosome painting in the Arizona collared peccary (Pecari tajacu, Tayassuidae): A comparison with the karyotype of pig and sheep". Chromosome Research 14 3 (2006): 243-251. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646049082&partnerID=MN8TOARS.
    10.1007/s10577-006-1040-y
  47. Adega, F.; Chaves, R.; Guedes-Pinto, H.; Heslop-Harrison, J.S.. "Physical organization of the 1.709 satellite IV DNA family in Bovini and Tragelaphini tribes of the Bovidae: sequence and chromosomal evolution". Cytogenetic and Genome Research 114 2 (2006): 140-146. http://dx.doi.org/10.1159/000093330.
    10.1159/000093330
  48. Adega, F.; Chaves, R.; Guedes-Pinto, H.. "Chromosome restriction enzyme digestion in domestic pig (Sus scrofa) constitutive heterochromatin arrangement". Genes and Genetic Systems 80 1 (2005): 49-56. http://www.scopus.com/inward/record.url?eid=2-s2.0-17644410086&partnerID=MN8TOARS.
    10.1266/ggs.80.49
  49. Cymbron, T.; Chaves, R.; Adega, F.; Guedes-Pinto, H.; Malheiro, M.I.; Chaves, Raquel; Adega, Filomena; Guedes-Pinto, Henrique; I. Malheiro, M.. "Standardization of MspI and HaeIII restriction karyotypes in cattle". Hereditas 140 2 (2004): 154-157. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942421619&partnerID=MN8TOARS.
    10.1111/j.1601-5223.2004.01801.x
  50. Chaves, R.; Adega, F.; Wienberg, J.; Guedes-Pinto, H.; Heslop-Harrison, J.S.; Chaves, Raquel; Adega, Filomena; et al. "Molecular cytogenetic analysis and centromeric satellite organization of a novel 8;11 translocation in sheep: A possible intermediate in biarmed chromosome evolution". Mammalian Genome 14 10 (2003): 706-710. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141450447&partnerID=MN8TOARS.
    10.1007/s00335-003-3004-2
  51. Chaves, R.; Adega, F.; Heslop-Harrison, J.S.; Guedes-Pinto, H.; Wienberg, J.; Chaves, Raquel; Adega, Filomena; Heslop-Harrison, J. S.; Guedes-Pinto, Henrique. "Complex satellite DNA reshuffling in the polymorphic t(1;29) Robertsonian translocation and evolutionary derived chromosomes in cattle". Chromosome Research 11 7 (2003): 641-648. http://www.scopus.com/inward/record.url?eid=2-s2.0-0142249469&partnerID=MN8TOARS.
    10.1023/A:1025952507959
  52. Chaves, R.; Adega, F.; Santos, S.; Guedes-Pinto, H.; Heslop-Harrison, J.S.. "In situ hybridization and chromosome banding in mammalian species". Cytogenetic and Genome Research 96 1-4 (2002): 113-116. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036047170&partnerID=MN8TOARS.
    10.1159/000063020
Online resource
  1. Adega, Filomena. Publicação de 286 sequências de DNA na base de dados GenBank do NCBI (entre 2001 e 2019). 2001. https://www.ncbi.nlm.nih.gov/nuccore/?term=Adega+f.
Thesis / Dissertation
  1. Ferreira, Daniela Perneta. "Molecular and Functional Characterization of a Satellite Non-Coding RNA ¿ FA-SAT, a Key Player of Cycling Cells". PhD, 2018. http://hdl.handle.net/10348/8811.
  2. Borges, Ana Luísa Pereira. "Molecular microevolution in cat mammary tumor lines: genomic and cytogenomic cell models". PhD, 2017. http://hdl.handle.net/10348/8239.
  3. Pereira, Sandra Louzada Gomes. "Karyotype restructuring in Rodentia: from evolution to cancer". PhD, 2015. http://hdl.handle.net/10348/5303.
  4. Escudeiro, Ana Cláudia Brandão Gomes Paulo. "Determinação dos padrões de transcrição da sequência FA-SAT em células proliferativas: modelo celular carnivora". Master, 2015. http://hdl.handle.net/10348/5295.
  5. Liberal, Ângela Leonor Castanheira. "Estudo comparativo de parâmetros químicos e de bioatividades entre diferentes variedades de perpétua (género Gomphrena, Amaranthaceae: Caryophyllales)". Master, 2015. http://hdl.handle.net/10348/6347.
  6. Conceição, Carlota José Fernandes da. "Definição do perfil transcricional da sequência de DNA satélite major de Rattus norvegicus num modelo celular tumoral". Master, 2014. http://hdl.handle.net/10348/5465.
  7. Teixeira, Ana Isabel do Paço. "Repetitive DNA sequences in rodentia genomes: its involvement in chromosome architecture reshuffling and in genome functionality". PhD, 2014. http://hdl.handle.net/10348/4791.
  8. Castro, João Pedro Leite. "Caracterização citogenética e análise da expressão dos genes Mycn e Erbb2 da linha celular tumoral de Rattus norvegicus, CLS-ACI-1". Master, 2014. http://hdl.handle.net/10348/3408.
  9. Borges, Ana Luísa Pereira. "Modelos celulares e genéticos em tumores mamários de gata". Master, 2009. http://hdl.handle.net/10348/2158.
  10. Teixeira, Ana Isabel do Paço. "Organização da fracção repetitiva nos genomas de Cricetus cricetus, Peromyscus eremicus (Família Cricetidae) e Praomys tullbergi (Família Muridae). Considerações sobre a evolução do cromossoma X". Master, 2007. http://hdl.handle.net/10348/151.
  11. Adega, Filomena. "Physical organization in Cetartiodactyla. Modes of chromosomes and karyotypes evolution". PhD, Universidade de Trás-os-Montes e Alto Douro, 2006.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/07/02 A physical map of repetitive elements in the genomes of Iberian Peninsula chiropteran species 14th European Cytogenomics Conference
European Cytogenetics Association (France)
2018/06/15 "From useless to a leading role: the biology of genomes and chromosomes directed by satellite DNAs Encontro Anual da Sociedade Portuguesa de Genética
i3s- Instituto de Investigação e Inovação em Saúde, Porto (Porto, Portugal)
2009 SAT DNA in evolution and phylogenetic studies of wildlife species and their genomes. An overview of three examples XXXIV Jornadas Portuguesas de Genética
Sociedade Portuguesa de Genética (Lisbon, Portugal)
2008/11/21 Arquiteturas Cromossómicas no Genoma de Roedores I Jornadas de Genética e Biotecnologia
Universidade de Trás-os-Montes e Alto Douro (Vila Real, Portugal)
2008/07/04 O uso de pequenos animais como sistemas modelo para o estudo da genética do cancro Ciência 2008-Encontro com a Ciência em Portugal
Fundação Calouste Gulbenkian (Lisboa, Portugal)
2007 Major features in comparative genomic studies on peccaries and pig Microbiotec 2007 AND XXXIII Jornadas Portuguesas de Genética
Sociedade Portuguesa de Genética (Lisbon, Portugal)
2003/11/08 Chromosome evolution in Cetartiodactyla: Comparative Chromosome Painting between the javelina (Pecari tajacu, Tayassuidae) and sheep (Ovis aries, Bovidae) I Congresso Português sobre a Fauna Selvagem
WAVES Portugal, Universidade de Trás-os-Montes e Alto Douro (Vila Real, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2023 - Current Isolation and characterization of transposable elements in chiropteran genomes
Co-supervisor of Francisca Manuela Teixeira Fernandes Castro
Genética Molecular Comparativa e Tecnológica (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023 - Current A cytogenomic analysis of some Portuguese chiropterans: the first approach to characterize this model organism
Co-supervisor of Sara Costa
 Biologia Clínica Laboratorial (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023 - Current Experiência na área de Citogenética convencional e FISH no diagnóstico de Leucemias Mielóides
Co-supervisor of Andreia Pereira
 Biologia Clínica Laboratorial
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023 - Current Experiência na área de Citogenética convencional e FISH no diagnostico de Leucemias Linfoides
Co-supervisor of Mafalda Saianda
 Biologia Clínica Laboratorial (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022 - Current Innovative silk coated cubosomal nanostructures for cancer therapy
Co-supervisor
 GMC (PhD)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022 - Current Análise da dinâmica mutacional do gene da proteína Spike (S) do vírus SARS-CoV-2 e sua influência na eficácia das vacinas para combate à COVID-19
Supervisor
 Mestrado em Biotecnologia para as Ciências da Saúde (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2020/01/21 - Current A web platform of Human Transposable Elements: link to disease
Co-supervisor
 GMC (PhD)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022/01/01 - 2022/12/31 How the mobilome shapes genomes: a journey across bat species from the North of Portugal, FCT grant 2021.07537.BD
Supervisor
 GMC (PhD)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022 - 2022/09 Experiência na área de Citogenética convencional e FISH no diagnóstico Pós-Natal
Co-supervisor
 Mestrado em Biotecnologia para as Ciências da Saúde (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021 - 2022/09 Métodos alternativos e céleres para o “upscaling” do diagnóstico molecular de SARS-CoV-2
Co-supervisor
 Mestrado em Biologia Clínica Laboratorial (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021 - 2022/07 A phylogenetic and evolutionary analysis of transposable elements in the wolf (Canis lupus, Canidae, Carnivora) genome
Co-supervisor
 GMCT (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2019 - 2022/02 Development, validation and implementation of an NGS gene panel approach for the diagnosis of renal amylodoises
Co-supervisor
 Biotecnologia para as Ciências da Saúde (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal

Centro de Genética Médica Doutor Jacinto Magalhães, Portugal
2019 - 2021/04 Dinâmica dos elementos transponíveis em modelos celulares para atrofia muscular espinhal
Supervisor
 Biotecnologia para as Ciências da Saúde (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2019 - 2021 Análise do envolvimento de elementos transponíveis na atrofia muscular espinhal
Supervisor
 Biotecnologia para as Ciências da Saúde (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2013 - 2020/01/06 “How satellite DNA comes into play in genomes? A Rodentia cell model approach”. Bolsa de Doutoramento da FCT ref.ª SFRH/BD/80808/2011
Co-supervisor
 Genética Molecular Comparativa (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2019 - 2020 Chromosomes and fertility in Sus scrofa and Bos taurus: an analysis of progenitors and embryos
Co-supervisor
 Biotecnologia para as Ciências da Saúde (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal

University of Kent School of Biosciences, United Kingdom
2018 - 2020 “Gennetta genneta: análise da arquitectura cromossómica e da fracção repetitiva”
Supervisor
 Genética Molecular Comparativa e Tecnológica (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2014 - 2019/09/27 What is the impact of the cattle chromosome polymorphism Rb t(1;29) in Bovini genome biodiversity and functionality?. Bolsa de Doutoramento da FCT ref.ª SFRH/BD/98122/2013
Co-supervisor
 Genética Molecular Comparativa (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2012 - 2018/01/19 “Molecular and Functional Characterization of a satellite non-coding RNA -FA-SAT- a key player of cycling cells” Bolsa de Doutoramento da FCT ref.ª SFRH/BD/80446/2011
Co-supervisor
 Genética Molecular Comparativa (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2009 - 2017/09/22 “Molecular microevolution in cat mammary lines: Genomic and Cytogenomics cell models”. Bolsa de Doutoramento da FCT ref.ª SFRH/BD/48392/2008
Co-supervisor
 Genética Molecular Comparativa (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2008 - 2015/12/18 “The Rattus norvegicus cell model: an integrated analysis of chromosome architecture, genes and satellite non coding sequences”. Bolsa de Doutoramento da FCT ref.ª SFRH/BD/41576/2007
Co-supervisor
 Genética Molecular Comparativa (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2014 - 2015/10 Estudo comparativo de parâmetros químicos e de bioatividades entre diferentes espécies de perpétua (género Gomphrena, Amaranthaceae: Caryophyllales”
Supervisor
 Genética Molecular Comparativa e Tecnológica (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2008 - 2014/07 Repetitive DNA Sequences in Rodentia Genomes. Its involvement in chromosome architecture reshuffling and in genome functionality.” Bolsa de Doutoramento da FCT ref.ª SFRH/BD/41574/2007
Co-supervisor
 Genética Molecular Comparativa (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2012 - 2014/04 “Defining the patterns of RNO-SAT1 transcription in Cancer Cell lines”
Supervisor
 Biotecnologia para as Ciências da Saúde (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2012 - 2013/11 “Defining the patterns of FA-SAT transcription in proliferative cells: A Carnivora cell model”
Co-supervisor
 Genética Molecular Comparativa e Tecnológica (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2007 - 2013/05 Karyotype restructuring in Rodentia: from Evolution to Cancer Bolsa de Doutoramento da FCT ref.ª SFRH/BD/25813/2005
Co-supervisor
Universidade de Trás-os-Montes e Alto Douro, Portugal
2011 - 2013/02 “Caracterização citogenética e análise de expressão dos genes Mycn e Erbb2 da linha celular tumoral de Rattus norvegicus, CLS-ACI-1”
Supervisor
 Biotecnologia para as Ciências da Saúde
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2007 - 2009/10 “Análise de tumores mamários de gata por técnicas de Citogenética Molecular”
Co-supervisor
 Genética Molecular Comparativa e Tecnológica (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2006 - 2008 “Organização da fracção repetitiva nos genomas de Cricetus cricetus, Peromyscus eremicus (Família Cricetidae) e Praomys tullbergi (Família Muridae)
Co-supervisor
 Genética Molecular Comparativa e Tecnológica (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2021/10/01 - 2021/10/02 Membro da Comissão Organizadora da RUSI WAVES, UTAD, Vila Real, Portugal, 1 a 2 de outubro de 2021. (2021/10/01 - 2021/10/02)
Meeting (Member of the Organising Committee)
 Universidade de Trás-os-Montes e Alto Douro, Portugal
2021/07/01 - 2021/07/02 Membro da Comissão Organizadora do 2nd International Meeting of the Portuguese Society of Genetics– IMPSG 2021, UTAD, Vila Real, Portugal, 1 a 2 de julho de 2021. (2021/07/01 - 2021/07/01)
Congress (Member of the Organising Committee)
 Universidade de Trás-os-Montes e Alto Douro, Portugal
2019/03/13 - 2019/03/13 Membro da Equipa Coordenadora (Ana Escudeiro, Filomena Adega, Raquel Chaves) do Workshop em "Cytogenetics and Bioinformatics in the experimental design of tools for Cancer Biomarkers" (2019/03/13 - 2019/03/17)
Workshop (Co-organisor)
 XI Jornadas de Genética e Biotecnologia/I Jornadas Ibéricas de Genética y Biotecnología", UTAD, Portugal
2017/09/21 - 2017/09/21 Membro da Equipa Coordenadora do Workshop em "Genetics as an essential tool in the Wild fauna conservation and management: Chromosomes", X Simpósio Internacional sobre a Fauna Selvagem (2017/09/21 - 2017/09/23)
Workshop (Co-organisor)
 WAVES Portugal, Universidade de Trás-os-Montes e Alto Douro, Portugal
2016/03/12 - 2016/03/12 Coordenação do Workshop "Microscopia: até onde a vista alcança?", inserido nas VIII Jornadas de Genética e Biotecnologia (2016/03/10 - 2017/03/12)
Workshop
 Universidade de Trás-os-Montes e Alto Douro, Portugal
2006/06/18 - 2006/06/21 Membro da Comissão Organizadora do “17th ECACGM, 17th European Colloquium on Animal Cytogenetics and Gene Mapping (2006/06/18 - 2006/06/21)
Meeting (Member of the Organising Committee)
 Fundação Calouste Gulbenkian, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal
2003/11/05 - 2003/11/08 Membro da Comissão Executiva na organização do I Congresso Português de Fauna Selvagem (2003/11/05 - 2003/11/08)
Congress (Member of the Organising Committee)
 Universidade de Trás-os-Montes e Alto Douro, Portugal
2001/04/18 - 2001/04/21 Membro da Comissão Executiva na organização do II Simpósio Internacional de Fauna Selvagem (2001/01/18 - 2001/04/21)
Conference (Member of the Organising Committee)
1997/03/18 - 1997/03/18 Membro da Comissão Organizadora das Jornadas de Bovinicultura (1997/03/18 - 1997/03/18)
Conference (Member of the Organising Committee)
1996/03/15 - 1996/03/15 Membro da Comissão Organizadora do 1º Encontro de Ovinicultura (1996/03/15 - 1996/03/15)
Conference (Member of the Organising Committee)

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2024/04/05 Application of an improved piezoelectric DNA-based biosensor to the detection of lung cancer
(Thesis) Arguer
 Bruna Beatriz Alves Rodrigues (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023/06 Caracterização de sequências de DNA satélite associadas a translocações Robertsonianas em humanos
(Thesis) Main arguer
 Gabriela Veríssimo Rodrigues (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023/03 Caracterização funcional do FA-SAT ncRNA em células humanas
(Thesis) Main arguer
 Marisa Nascimento Carvalho (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023/03 In vivo toxicity evaluation of Carbon nanoparticles
(Thesis) Main arguer
 Luís Sousa (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023/02/07 Aplicação da técnica de MLPA na pesquisa de alterações cromossómicas numéricas em produtos de abortamento
(Thesis) Main arguer
 Julieta Costa (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023/01/31 Development of piezoelectric DNA based biosensor applied to lung cancer
(Thesis) Main arguer
 Patrícia Gatinho Silva (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2023/01/11 Aplicação da técnica de FISH na pesquisa de mosaicismo cromossómico em amostras de mucosa bucal
(Thesis) Main arguer
 Megan Braga (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022/07/26 Aplicação de Técnicas de Citogenética e Genómica no estudo da Evolução do Cariótipo de Cobras da Península Ibérica.
(Thesis) Main arguer
 José Júlio Pereira Gantes da Costa (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022/07 Laboratory diagnosis of SARS-CoV-2 in the post-vaccination period for COVID-19
Supervisor
 Débora Adelaide Vareiro Marafona (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022/07 A phylogenetic and evolutionary analysis of transposable elements in the wolf (Canis lupus, Canidae, Carnivora) genome
Supervisor
 Maria Confraria Gaspar (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022/04/05 New Fluorescence-Based Biosensor For SARS-CoV-2 Detection
(Thesis) Main arguer
 Alexandra Lino (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2022/02 Development, validation and implementation of an NGS gene panel approach for the diagnosis of renal amylodoises
Supervisor
 Ana Rita Fernandes (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021/05 Análise do envolvimento de elementos transponíveis na atrofia muscular espinhal
Supervisor
 Catarina Cunha (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021/04 Dinâmica dos elementos transponíveis em modelos celulares para atrofia muscular espinhal
Supervisor
 Albano Ribeiro Pinto (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021 Estudo das doenças genéticas humanas na vertente técnica e científica: citogenética convencional e molecular- FISH
(Thesis) Main arguer
 Tiago José Ferreira da Silva (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2020/06 Gennetta genneta: análise da arquitectura cromossómica e da fracção repetitiva
Supervisor
 Valérie Pires de Carvalho (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2020 Pesquisa in silico de variações no número de cópias em painel de genes associados a cancro hereditário
(Thesis) Main arguer
 Vanessa Silveira Carvalho (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2019/07/11 Epidermal Growth Factor Receptor (EGFR): immunoexpression and mutation analysis in canine mammary cancer
(Thesis) Main arguer
 Ana Beatriz Gonçalves (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2019/06/27 Systemic factors and tumour progression
(Thesis) Main arguer
 Catarina Pinheiro (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2018/10 Provas de Doutoramento em Biologia Celular e Molecular, “Cytogenetic and molecular analyses in Palaemon species”
(Thesis) Main arguer
 Zeltia Torrecilla Pérez (PhD)
Universidade da Coruña, Spain
2018/01/31 Estudo de doentes com suspeita clínica de síndrome de microdeleção/microduplicação pela técnica de MLPA: Aplicação do painel P297 (MRC-Holland)
(Thesis) Main arguer
 Ana Marta Rosas (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2018 Alterações epigenéticas no abortamento espontâneo
(Thesis) Main arguer
 Sara Virgínia Fernandes Sampaio de Vasconcelos (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2017/12/20 Consequences of admixture and LGM on current genetic diversity gradients of American humans
(Thesis) Main arguer
 Catarina Branco (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2017/11/15 A Y-chromosome map between the gibbon Nomascus leucogenys and Humans: Evolutionary inferences and biomedical applications
(Thesis) Main arguer
 Liliana Costa (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2016/12/06 Establishing X-chromosome STR profiling for Bos taurus with a multiplex PCR approach
(Thesis) Main arguer
 Rute Gonçalves Ferreira (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2016/03 Provas de Doutoramento em Ciências, Especialidade em Química “Towards antioxidant and antitumor properties of wild medicinal plants traditionally used in Portugal: extracts, isolated flavonoids, and their human metabolites obtained by chemical synthesis”
(Thesis) Main arguer
 Cristina Rafaela dos Santos Albuquerque Guimarães (PhD)
Universidade do Minho, Portugal
2015/10 Estudo comparativo de parâmetros químicos e de bioatividades entre diferentes espécies de perpétua (género Gomphrena, Amaranthaceae: Caryophyllales
Supervisor
 Ângela Leonor Castanheira Liberal (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2015/02/27 p66Sch na toxicidade mitocondrial induzida pelo NEF numa linha hepatocelular
(Thesis) Main arguer
 Ana Marta Silva (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2014/12/15 Papel da adenosina na insuficiência cardíaca num modelo animal de hipertensão pulmonar
(Thesis) Main arguer
 Tânia Rodrigues (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2014/04 Definição do perfil transcricional da sequência de DNA satélite major de Rattus norvegicus num modelo celular tumoral
Supervisor
 Carlota José Fernandes da Conceição (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2013/11 Defining the patterns of FA-SAT transcription in proliferative cells: A Carnivora cell model
Supervisor
 Ana Cláudia Brandão Gomes Paulo Escudeiro (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2013/05 Provas de Doutoramento em Genética Molecular Comparativa e Tecnológica (3º ciclo) “Bar-Codes cromossómicos para os genomas dos organismos modelo Rato/Ratinho - Aplicação a cariótipos complexos de carcinomas de bexiga em rato”
Supervisor
 Sandra Louzada Gomes (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2013/02 Caracterização citogenética e análise de expressão dos genes Mycn e Erbb2 da linha celular tumoral de Rattus norvegicus, CLS-ACI-1
Supervisor
 João Pedro Leite Castro (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2012/05 Detecção de alterações cromossómicas em fetos com malformações ecográficas utilizando MLPA
(Thesis) Main arguer
 Sara Cristina Calejo Campos (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2012/03 Provas de Doutoramento em Medicina Veterinária (3º Ciclo) ”The metastatic process in cat mammary tumours - genomic and functional characterization of candidate genes"
(Thesis) Main arguer
 Cláudia Sofia Narciso Fernandes Baptista (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010/01 O processo de cancerização da mama e ovário: Expressão dos marcadores de células estaminais ALDH1 e CD44 e amplificação do HER2
(Thesis) Main arguer
 Oriana Alexandra de Paixão Praças Marques (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2010/01 Alterações moleculares no carcinoma da mama e ovário: Expressão de MCT1 e MCT4 e amplificação do HER2
(Thesis) Main arguer
 Arnaud Fabian da Cruz Paula (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2009/10 Análise de tumores mamários de gata por técnicas de Citogenética Molecular
Supervisor
 Ana Luísa Pereira Borges (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2009/06 Análise molecular em Suiformes - O gene POUF1
(Thesis) Main arguer
 Vanessa Sofia Lopes Rodrigues (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2008 Comparative Chromosome Painting entre os Genomas das espécies Muridae (Rodentia) Praomys tullbergi, Mus musculus e Rattus norvegicus: Arquitectura Cromossómica
Supervisor
 Susana Manuela Alves Meles (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2008 Organização da fracção repetitiva nos genomas de Cricetus cricetus, Peromyscus eremicus (Família Cricetidae) e Praomys tullbergi (Família Muridae). Considerações sobre a evolução do Cromossoma X
Supervisor
 Ana Isabel do Paço Teixeira (Master)
Universidade de Trás-os-Montes e Alto Douro, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2023 - Current Animals
2023 - Current Genomes
2022 - Current Genes
2021 - Current Cells MDPI
2020 - Current Ciência Rural
2020 - Current Aging
2019/11/22 - Current BMC Genomics (1471-2164) Springer (Biomed Central Ltd.)
2019 - Current Scientific Reports (2045-2322) Springer Science and Business Media LLC
2018 - Current Italian Journal of Zoology
2017 - Current Journal of Molecular Evolution (1432-1432) Springer-Verlag
2015 - Current PLoS ONE (1932-6203) Public Library of Science
2015 - Current Bioorganic & Medicinal Chemistry (0968-0896) Elsevier
2015 - Current European Journal of Medicinal Chemistry (0223-5234) Elsevier
2014 - Current Journal of mammology (0022-2372) JSTOR

Association member

Society Organization name Role
2021 - Current Portuguese Socyety of Genetics/Sociedade Portuguesa de Genética
2018 - Current Sociedade Euromediterrânica de Vigilância de Fauna Selvagem, WAVES-Portugal Secretária da Mesa da Assembleia Geral
2018 - Current European Cytogenetics Association

Committee member

Activity description
Role 		Institution / Organization
2020/05/01 - 2022/02/28 Directora de gestão laboratorial do Centro de testagem COVID-19 da UTAD
Director
 Centro de Testagem COVID-19, UTAD, Portugal
2021/06/01 - 2021/06/01 Membro da Comissão científica do Congresso internacional – One Health
Member
 Universidade de Trás-os-Montes e Alto Douro, Portugal
2003/11/05 - 2003/11/08 Membro da Comissão Executiva na organização do “I Congresso Português de Fauna Selvagem”
Member
 WAVES Portugal, Universidade de Trás-os-Montes e Alto Douro, Portugal
2001/04/18 - 2001/04/21 Membro da Comissão Executiva na organização do “II Simpósio Internacional de Fauna Selvagem”
Member
 WAVES Portugal, Universidade de Trás-os-Montes e Alto Douro, Portugal

Conference scientific committee

Conference name Conference host
2017/03/08 - 2017/03/10 IX Jornadas de Genética e Biotecnologia
2014/03 - 2014/03 VI Jornadas de Genética e Biotecnologia e do II Encontro Nacional de Estudantes de Biotecnologia

Consulting

Activity description Institution / Organization
2022/03/01 - Current Genomics and Cytogenomics advanced Services Universidade de Trás-os-Montes e Alto Douro, Portugal
2020/05 - 2022/02 Molecular Diagnosis of SARS-CoV2 during the pandemics Centro de Testagem COVID-19, UTAD, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2021 - Current Frontiers in Genetics (1664-8021) Frontiers
2019 - Current Ciência Rural (0103-8478) SciELO
2018 - Current Italian Journal of Zoology (1748-5851) Informa UK (Taylor & Francis)
Distinctions

Award

2023 Menção honrosa para comunicação oral nas XV Jornadas de Genética e Biotecnologia e V Jornadas Ibéricas de Genética y Biotecnología: Unveiling the role of transposable elements in bats genome evolution
Universidade de Trás-os-Montes e Alto Douro, Portugal
2021 Social Responsability/Responsabilidade Social
Universidade de Trás-os-Montes e Alto Douro, Portugal
2019 Primeira Menção Honrosa para comunicação Oral "The Bovinae rob(1;29) as a model to study the translocation mechanism underlying Robertsonian Centric Fusions
Organização das XI Jornadas de Genética e Biotecnologia/I Jornadas Ibéricas de Genética y Biotecnologia, Portugal
2019 Primeira Menção Honrosa para comunicação em poster "Cytogenetics as a species identification tool: a particular case of a Viverrinae) (Carnivora, Viverridae) individual""
Organização das XI Jornadas de Genética e Biotecnologia/I Jornadas Ibéricas de Genética y Biotecnologia, Portugal
2019 Segunda Menção Honrosa para comunicação em poster "Breaking down human satellite DNAs and its ncRNAs in proliferative cells
Organização das XI Jornadas de Genética e Biotecnologia/I Jornadas Ibéricas de Genética y Biotecnologia, Portugal
2017 Menção honrosa para comunicação Oral, Melhor Comunicação Oral "FA-SAT: doomed to repeat and transcribe! But why?
Organização das IX Jornadas de Genética e Biotecnologia, Universidade de Trás-os-Montes e Alto Douro, Portugal
2009 Prémio Investigador Tristão Mello-Sampayo para o melhor trabalho oral na área da Citogenética/Genómica Comparativa e Evolutiva
Sociedade Portuguesa de Genética, Organização das XXXIV Jornadas Portuguesas de Genética, Portugal
2007 Prémio de "Melhor comunicação", atribuído pelo trabalho "Major features in comparative genomic studies on peccaries and pig"
Sociedade Portuguesa de Genética, Organização das XXXIII Jornadas Portuguesas de Genética, Portugal

Other distinction

2012 Homenagem da Sociedade Portuguesa de Senologia, ao grupo/equipa pela investigação em cancro da mama, em Portugal
Sociedade Portuguesa de Senologia, Portugal