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Identification

Personal identification

Full name
Carmen Agustín-Pavón

Citation names

  • Agustín-Pavón, Carmen

Author identifiers

Ciência ID
2911-8D24-2069
ORCID iD
0000-0002-6725-6954
Education
Degree Classification
2004/01/01 - 2008/06/17
Concluded
 Doctora en Neurociencias (Doctor)
Universitat de València, Spain
"Neurochemistry of pheromone induced reward" (THESIS/DISSERTATION)
1998/09/01 - 2003/09/30
Concluded
 Licenciatura en Biología (Licence)
Universitat de València, Spain
Affiliation

Science

Category
Host institution 		Employer
2014/10/01 - 2015/09/30 Postdoc (Research) Universitat Jaume I, Spain
2014/01/01 - 2014/09/30 Postdoc (Research) Imperial College London Faculty of Natural Sciences, United Kingdom
2010/11/01 - 2013/12/31 Postdoc (Research) Centre for Genomic Regulation, Spain
2009/01/05 - 2010/09/30 Postdoc (Research) University of Cambridge, Department of Physiology, Development and Neuroscience, United Kingdom
2008/05/01 - 2009/12/31 Research Assistant (Research) Universitat de València, Spain
2004/01/01 - 2008/06/17 Research Trainee (Research) Universitat de València, Spain

Teaching in Higher Education

Category
Host institution 		Employer
2019/12/20 - Current Associate Professor (University Teacher) Universitat de València, Spain
2016/10/01 - 2019/12/19 Assistant Professor (University Teacher) Universitat de València, Spain
2015/10/01 - 2016/09/30 Assistant Professor (University Teacher) Universitat Jaume I, Spain
Projects

Grant

Designation Funders
2023/04/01 - Current The Gonadotropin Releasing Hormone (GnRH) neuroendocrine system as a therapeutic target in Rett
FinRett022023
Co-Principal Investigator (Co-PI)
FinRett
Ongoing
2020/06 - 2024/05 Structural plasticiy in the olfactory system: impact of maternity, early life stress and Mecp2 deficiency
PID2019-107322GB-C22
Principal investigator
Gobierno de España
Ongoing
2019/10/07 - 2021/04/30 THE ENDOCANNABINOID SYSTEM AND RETT SYNDROME: NEUROANATOMICAL NEUROCHEMICAL AND BEHAVIOURAL ANALYSES.
Project022019
Principal investigator
FinRett
Concluded
2016 - 2018 Maternal Aggression, Reward and Smell
BFU2016-77691-C2-1-P
 Ministerio de Economía y Competitividad
Outputs

Publications

Journal article
  1. María Abellán-Álvaro; Fernando Martínez-García; Enrique Lanuza; Carmen Agustín-Pavón. "Inhibition of the medial amygdala disrupts escalated aggression in lactating female mice after repeated exposure to male intruders". Communications Biology (2022): https://doi.org/10.1038/s42003-022-03928-2.
    10.1038/s42003-022-03928-2
  2. Navarro-Moreno, C.; Barneo-Muñoz, M.; Ibáñez-Gual, M.V.; Lanuza, E.; Agustín-Pavón, C.; Sánchez-Catalán, M.J.; Martínez-García, F.. "Becoming a mother shifts the activity of the social and motivation brain networks in mice". iScience 25 7 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85132235888&partnerID=MN8TOARS.
    10.1016/j.isci.2022.104525
  3. Torres-Pérez, J.V.; Martínez-Rodríguez, E.; Forte, A.; Blanco-Gómez, C.; Stork, O.; Lanuza, E.; Santos, M.; Agustín-Pavón, C.. "Early life stress exacerbates behavioural and neuronal alterations in adolescent male mice lacking methyl-CpG binding protein 2 (Mecp2)". Frontiers in Behavioral Neuroscience 16 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85137972892&partnerID=MN8TOARS.
    10.3389/fnbeh.2022.974692
  4. Salais-López, H.; Abellán-Álvaro, M.; Bellés, M.; Lanuza, E.; Agustin-Pavon, C.; Martínez-Garciá, F.. "Maternal Motivation: Exploring the Roles of Prolactin and Pup Stimuli". Neuroendocrinology 111 9 (2021): 805-830. http://www.scopus.com/inward/record.url?eid=2-s2.0-85098713104&partnerID=MN8TOARS.
    10.1159/000510038
  5. Martín-Sánchez, A.; Valera-Marín, G.; Hernández-Martínez, A.; Lanuza, E.; Martínez-García, F.; Agustín-Pavón, C.. "Corrigendum: Wired for motherhood: induction of maternal care but not maternal aggression in virgin female CD1 mice (Front. Behav. Neurosci., (2015), 9, (197), 10.3389/fnbeh.2015.00197)". Frontiers in Behavioral Neuroscience 15 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85105942805&partnerID=MN8TOARS.
    10.3389/fnbeh.2021.671259
  6. Abellán-Álvaro, M.; Ayala, G.; Barneo-Muñoz, M.; Martínez-García, F.; Agustín-Pavón, C.; Lanuza, E.. "Motherhood-induced gene expression in the mouse medial amygdala: Changes induced by pregnancy and lactation but not by pup stimuli". FASEB Journal 35 9 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85113541867&partnerID=MN8TOARS.
    10.1096/fj.202100163RR
  7. Abellán-Álvaro, M.; Stork, O.; Agustín-Pavón, C.; Santos, M.. "MeCP2 haplodeficiency and early-life stress interaction on anxiety-like behavior in adolescent female mice". Journal of Neurodevelopmental Disorders 13 1 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85121343382&partnerID=MN8TOARS.
    10.1186/s11689-021-09409-7
  8. Elena Martínez-Rodríguez; Ana Martín-Sánchez; Emre Kul; Aparajita Bose; Francisco José Martínez-Martínez; Oliver Stork; Fernando Martínez-García; et al. "Male-specific features are reduced in Mecp2-null mice: analyses of vasopressinergic innervation, pheromone production and social behaviour". Brain Structure and Function 225 7 (2020): 2219-2238. https://doi.org/10.1007/s00429-020-02122-6.
    10.1007/s00429-020-02122-6
  9. Navarro-Moreno, C.; Sanchez-Catalan, M.J.; Barneo-Muñoz, M.; Goterris-Cerisuelo, R.; Belles, M.; Lanuza, E.; Agustin-Pavon, C.; Martinez-Garcia, F.. "Pregnancy Changes the Response of the Vomeronasal and Olfactory Systems to Pups in Mice". Frontiers in Cellular Neuroscience 14 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85098735562&partnerID=MN8TOARS.
    10.3389/fncel.2020.593309
  10. "Activation of MORs in the VTA induces changes on cFos expression in different projecting regions: Effect of inflammatory pain.". Neurochemistry international (2019): https://doi.org/10.1016/j.neuint.2019.104521.
    10.1016/j.neuint.2019.104521
  11. "Lack of MeCP2 leads to region-specific increase of doublecortin in the olfactory system.". Brain structure & function (2019): https://doi.org/10.1007/s00429-019-01860-6.
    10.1007/s00429-019-01860-6
  12. Salais-López, H.; Agustín-Pavón, C.; Lanuza, E.; Martínez-García, F.; Hugo Salais-Lopez; Carmen Agustin-Pavon; Enrique Lanuza; Fernando Martinez-Garcia. "The maternal hormone in the male brain: Sexually dimorphic distribution of prolactin signalling in the mouse brain". PLoS ONE 13 12 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85058789249&partnerID=MN8TOARS.
    10.1371/journal.pone.0208960
  13. "Glutamate and Opioid Antagonists Modulate Dopamine Levels Evoked by Innately Attractive Male Chemosignals in the Nucleus Accumbens of Female Rats.". Frontiers in neuroanatomy (2017): http://europepmc.org/abstract/med/28280461.
    10.3389/fnana.2017.00008
  14. "Deimmunization for gene therapy: host matching of synthetic zinc finger constructs enables long-term mutant Huntingtin repression in mice.". Molecular neurodegeneration (2016): http://europepmc.org/abstract/med/27600816.
    10.1186/s13024-016-0128-x
  15. Salais-López H; Lanuza E; Agustín-Pavón C; Martínez-García F; Salais-López, H.; Lanuza, E.; Agustín-Pavón, C.; Martínez-García, F.. "Tuning the brain for motherhood: prolactin-like central signalling in virgin, pregnant, and lactating female mice.". Brain Structure and Function 222 2 (2016): 895-921. http://europepmc.org/abstract/med/27344140.
    10.1007/s00429-016-1254-5
  16. Carmen Agustín-Pavón. "Explorant teràpies biotecnològiques contra les malalties neurodegeneratives". Anuari de l'Agrupació Borrianenca de Cultura.Revista de recerca humanística i científica {XXVII (2016): 89-99. https://doi.org/10.6035%2Fanuari.2016.27.9.
    10.6035/anuari.2016.27.9
  17. Otero-García M; Agustín-Pavón C; Lanuza E; Martínez-García F; Otero-García, M.; Agustín-Pavón, C.; Lanuza, E.; Martínez-García, F.. "Distribution of oxytocin and co-localization with arginine vasopressin in the brain of mice.". Brain Structure and Function 221 7 (2015): 3445-3473. http://europepmc.org/abstract/med/26388166.
    10.1007/s00429-015-1111-y
  18. Fortes-Marco L; Lanuza E; Martínez-García F; Agustín-Pavón C. "Avoidance and contextual learning induced by a kairomone, a pheromone and a common odorant in female CD1 mice.". (2015): http://europepmc.org/abstract/med/26500474.
    10.3389/fnins.2015.00336
  19. Martín-Sánchez A; Valera-Marín G; Hernández-Martínez A; Lanuza E; Martínez-García F; Agustín-Pavón C. "Wired for motherhood: induction of maternal care but not maternal aggression in virgin female CD1 mice.". (2015): http://europepmc.org/abstract/med/26257621.
    10.3389/fnbeh.2015.00197
  20. Agustín-Pavón C; Isalan M. "Synthetic biology and therapeutic strategies for the degenerating brain: Synthetic biology approaches can transform classical cell and gene therapies, to provide new cures for neurodegenerative diseases.". (2014): http://europepmc.org/abstract/med/25100403.
    10.1002/bies.201400094
  21. Otero-Garcia M; Martin-Sanchez A; Fortes-Marco L; Martínez-Ricós J; Agustin-Pavón C; Lanuza E; Martínez-García F. "Extending the socio-sexual brain: arginine-vasopressin immunoreactive circuits in the telencephalon of mice.". (2014): http://europepmc.org/abstract/med/23625152.
    10.1007/s00429-013-0553-3
  22. Agustín-Pavón C; Martínez-García F; Lanuza E. "Focal lesions within the ventral striato-pallidum abolish attraction for male chemosignals in female mice.". (2014): http://europepmc.org/abstract/med/24269269.
    10.1016/j.bbr.2013.11.020
  23. Shiba Y; Santangelo AM; Braesicke K; Agustín-Pavón C; Cockcroft G; Haggard M; Roberts AC. "Individual differences in behavioral and cardiovascular reactivity to emotive stimuli and their relationship to cognitive flexibility in a primate model of trait anxiety.". (2014): http://europepmc.org/abstract/med/24795587.
    10.3389/fnbeh.2014.00137
  24. Busquets-Garcia A; Gomis-González M; Guegan T; Agustín-Pavón C; Pastor A; Mato S; Pérez-Samartín A; et al. "Targeting the endocannabinoid system in the treatment of fragile X syndrome.". (2013): http://europepmc.org/abstract/med/23542787.
    10.1038/nm.3127
  25. Garriga-Canut M; Agustín-Pavón C; Herrmann F; Sánchez A; Dierssen M; Fillat C; Isalan M. "Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice.". (2012): http://europepmc.org/abstract/med/23054839.
    10.1073/pnas.1206506109
  26. Agustín-Pavón C; Braesicke K; Shiba Y; Santangelo AM; Mikheenko Y; Cockroft G; Asma F; et al. "Lesions of ventrolateral prefrontal or anterior orbitofrontal cortex in primates heighten negative emotion.". (2012): http://europepmc.org/abstract/med/22502990.
    10.1016/j.biopsych.2012.03.007
  27. Agustín-Pavón C; Parkinson J; Man MS; Roberts AC. "Contribution of the amygdala, but not orbitofrontal or medial prefrontal cortices, to the expression of flavour preferences in marmoset monkeys.". (2011): http://europepmc.org/abstract/med/21848920.
    10.1111/j.1460-9568.2011.07813.x
  28. Rinaldi A; Romeo S; Agustín-Pavón C; Oliverio A; Mele A. "Distinct patterns of Fos immunoreactivity in striatum and hippocampus induced by different kinds of novelty in mice.". (2010): http://europepmc.org/abstract/med/20736076.
    10.1016/j.nlm.2010.08.004
  29. Mikheenko Y; Man MS; Braesicke K; Johns ME; Hill G; Agustín-Pavón C; Roberts AC. "Autonomic, behavioral, and neural analyses of mild conditioned negative affect in marmosets.". (2010): http://europepmc.org/abstract/med/20364879.
    10.1037/a0018868
  30. Agustín-Pavón C; Martínez-Ricós J; Martínez-García F; Lanuza E. "Role of nitric oxide in pheromone-mediated intraspecific communication in mice.". (2009): http://europepmc.org/abstract/med/19799918.
    10.1016/j.physbeh.2009.09.011
  31. Martínez-García F; Martínez-Ricós J; Agustín-Pavón C; Martínez-Hernández J; Novejarque A; Lanuza E. "Refining the dual olfactory hypothesis: pheromone reward and odour experience.". (2009): http://europepmc.org/abstract/med/18977394.
    10.1016/j.bbr.2008.10.002
  32. Martínez-Ricós J; Agustín-Pavón C; Lanuza E; Martínez-García F. "Role of the vomeronasal system in intersexual attraction in female mice.". (2008): http://europepmc.org/abstract/med/18384964.
    10.1016/j.neuroscience.2008.02.002
  33. Agustín-Pavón C; Martínez-Ricós J; Martínez-García F; Lanuza E. "Sex versus sweet: opposite effects of opioid drugs on the reward of sucrose and sexual pheromones.". (2008): http://europepmc.org/abstract/med/18410180.
    10.1037/0735-7044.122.2.416
  34. Lanuza E; Novejarque A; Martínez-Ricós J; Martínez-Hernández J; Agustín-Pavón C; Martínez-García F. "Sexual pheromones and the evolution of the reward system of the brain: the chemosensory function of the amygdala.". (2008): http://europepmc.org/abstract/med/18331915.
    10.1016/j.brainresbull.2007.10.042
  35. Agustín-Pavón C; Martínez-Ricós J; Martínez-García F; Lanuza E. "Effects of dopaminergic drugs on innate pheromone-mediated reward in female mice: a new case of dopamine-independent "liking.".". (2007): http://europepmc.org/abstract/med/17907824.
    10.1037/0735-7044.121.5.920
  36. Martínez-Ricós J; Agustín-Pavón C; Lanuza E; Martínez-García F. "Intraspecific communication through chemical signals in female mice: reinforcing properties of involatile male sexual pheromones.". (2007): http://europepmc.org/abstract/med/17085679.
    10.1093/chemse/bjl039
Preprint
  1. Michele Prina; Rafael Esteve-Pérez; Cinta Navarro-Moreno; María Abellán-Álvaro; Enrique Lanuza; MªJosé Sánchez-Catalán; Fernando Martínez-García; Carmen Agustín-Pavón; Jose Vicente Torres-Pérez. "Doublecortin-immunoreactive immature neurons in the olfactory system across pregnancy and lactation in female mice". 2023. https://doi.org/10.1101/2023.02.08.527694.
    10.1101/2023.02.08.527694
  2. María Abellán-Álvaro; Ferran Martinez-Garcia; Enrique Lanuza; Carmen Agustin-Pavon. "Inhibition of the medial amygdala disrupts escalated aggression in lactating female mice after repeated exposure to male intruders". 2022. https://doi.org/10.21203/rs.3.rs-1490156/v1.
    10.21203/rs.3.rs-1490156/v1

Other

Other output
  1. Inhibition of the medial amygdala disrupts escalated aggression in lactating female mice after repeated exposure to male intruders. 2022. Abellán-Álvaro, M.; Martínez-García, F.; Lanuza, E.; Agustín-Pavón, C.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85134034453&partnerID=MN8TOARS.
    10.21203/rs.3.rs-1490156