Fernando Henrique Borges (2210-347F-E860)

Curriculum Vitae

Fernando Henrique Borges

Graduated in Pharmacy, PhD and Master’s degree in health sciences, postgraduate degree in Clinical Oncology, ministered disciplines of pharmaceutical chemistry, human genetics, clinical biochemistry and supervised training. Currently a member of Brazilian Society of Pharmacists in Oncology. Contemplated with full scholarship for study and research in master and PhD degree, including an integral scholarship for international mobility, which was held at Faculty of Sports at University of Porto. With experience in oncology clinical pharmacy area, oxidative stress, cancer cachexia, cardiac cachexia and muscular adaptations.

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Identification

Personal identification

Full name: Fernando Henrique Borges

Citation names

Borges, Fernando
Borges, FH
Borges, F

Author identifiers

Ciência ID: 2210-347F-E860
ORCID iD: 0000-0002-7602-4119

Addresses

Rua Ernani Lacerda de Athayde, 1260, 86055630, Londrina, Paraná, Brazil (Personal)

Websites

http://lattes.cnpq.br/7060125942334400 (Scholar)
https://www.linkedin.com/in/fernando-borges-b33832135/ (Professional)

Knowledge fields

Medical and Health Sciences - Basic Medicine - Pathology
Medical and Health Sciences - Basic Medicine - Physiology
Natural sciences - Biological Sciences - Molecular Biology

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Intermediate (B1)	Upper intermediate (B2)	Intermediate (B1)	Intermediate (B1)	Upper intermediate (B2)
Spanish; Castilian	Intermediate (B1)	Intermediate (B1)	Intermediate (B1)	Intermediate (B1)	Intermediate (B1)

Education

	Degree	Classification
2020/08/15 - 2021/08/10 Concluded	MBA in Financial Management, Auditing and Controlling (Postgraduate Certificate) Faculdade Estratego, Brazil
2020/07/20 - 2021/07/20 Concluded	MBA in People and Leadership Management (Postgraduate Certificate) Major in Gestão Faculdade Polis Civita, Brazil
2014/03/03 - 2018/03/23 Concluded	Health Science (Doctor) Universidade Estadual de Londrina, Brazil "Creatine supplementation in Walker-256 tumor-bearing rats" (THESIS/DISSERTATION)
2016/07/09 - 2017/10/17 Concluded	Clínical Oncology (Postgraduate Certificate) Major in Oncology Centro Goiano de Pesquisa e Pós-Graduação, Brazil "Muscle complications during tumor development in laboratory animals" (THESIS/DISSERTATION)
2016/04/04 - 2017/03/29 Concluded	PhD mobility (Doutoramento) Universidade do Porto, Portugal
2011/03/07 - 2013/10/04 Concluded	Health Science (Master) Major in pathology Universidade Estadual de Londrina, Brazil "Relation between oxidative stress and cardiac cachexia in Wistar rats bearing Walker-256 tumor solid form" (THESIS/DISSERTATION)
2005/07/18 - 2009/08/21 Concluded	Pharmacy (Graduado) Instituto de Ensino Superior de Londrina, Brazil "Analysis of Individual or Standardized Treatment in Parenteral Nutrition Therapy" (THESIS/DISSERTATION)

Affiliation

Science

	Category Host institution	Employer
2022/02/10 - Current	Postdoc (Research)	Universidade Estadual de Londrina, Brazil

Teaching in Higher Education

	Category Host institution	Employer
2013/04 - Current	Associate Professor (University Teacher)	Faculdade de Ensino Superior Dom Bosco, Brazil

2022/07/15 - 2023/02/20	Visiting Professor (University Teacher)	Fundação Regional do Ensino Superior em Araras, Brazil
	Fundação Regional do Ensino Superior em Araras, Brazil
2017/04/10 - 2019/12/18	Invited Assistant Professor (University Teacher)	Centro Universitário Filadélfia, Brazil
	Centro Universitário Filadélfia, Brazil

Other Careers

	Category Host institution	Employer
2021/08/05 - 2022/09/08	Assessor Superior (Técnico Superior de Saúde - Farmácia)	Droga Raia, Brazil

2020/01/13 - 2021/01/19	Técnico Farmacêutico Especialista (Técnico Farmacêutico)	Grupo Oncoclin, Brazil

2017/12/18 - 2019/06/10	Técnico Farmacêutico Especialista Principal (Técnico Farmacêutico)	Hospital Evangélico de Londrina, Brazil

Projects

Grant

	Designation	Funders
2014/03/03 - 2018/03/23	Hematological disorders, oxidative and functional of the cardiac muscle in Walker-256 tumor-bearing rats and supplemented with creatine 09434 PhD Student Fellow Universidade Estadual de Londrina, Brazil	Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Concluded
2011/03/07 - 2013/10/04	Relation between oxidative stress and cardiac cachexia in Wistar rats bearing Walker-256 tumor solid form 08426 Master Student Fellow Universidade Estadual de Londrina, Brazil	Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Concluded

Contract

	Designation	Funders
2022/09/01 - Current	Discovery of antiviral lead compounds for combating COVID-19 from a chemically diverse compound library (Capes Pharmaceuticals) 12/2022 Post-doc Fellow Universidade Estadual de Londrina, Brazil	Ongoing
2022/02/10 - Current	Evaluation of possible estrogen protection and its interaction with NO-synthase isoforms on cardiovascular, autonomic and oxidative parameters in rats with 6-hydroxydopamine-induced parkinsonism 019/2021 Post-doc	Ongoing
2017/05/04 - 2017/08/24	Topics in Neuroscience 12974/2012 PhD Student Fellow	Concluded

Outputs

Publications

Journal article

Poliana Camila Marinelo; Paola S Cella; Mayra T J Testa; Philippe B Guirro; Wallison A S Brito; Borges, Fernando; Rubens Cecchini; et al. "Creatine supplementation exacerbates ethanol-induced hepatic damage in mice". Nutrition (2019): http://dx.doi.org/10.1016/j.nut.2019.05.004.
10.1016/j.nut.2019.05.004
Paola S Cella; Poliana Camila Marinelo; Borges, Fernando; Diogo F Ribeiro; Patricia Chimin; Mayra T J Testa; Philippe B Guirro; et al. "Creatine supplementation in Walker-256 tumor-bearing rats prevents skeletal muscle atrophy by attenuating systemic inflammation and protein degradation signaling". European Journal of Nutrition (2019): http://dx.doi.org/10.1007/s00394-019-01933-6.
10.1007/s00394-019-01933-6
Padilha, C.S.; Borges, F.H.; Costa Mendes da Silva, L.E.; Frajacomo, F.T.T.; Jordao, A.A.; Duarte, J.A.; Cecchini, R.; Guarnier, F.A.; Deminice, R.. "Resistance exercise attenuates skeletal muscle oxidative stress, systemic pro-inflammatory state, and cachexia in Walker-256 tumor-bearing rats". Applied Physiology, Nutrition and Metabolism 42 9 (2017): 916-923. http://www.scopus.com/inward/record.url?eid=2-s2.0-85030719305&partnerID=MN8TOARS.
10.1139/apnm-2016-0436
Marinello, P.C.; Bernardes, S.S.; Guarnier, F.A.; Da Silva, T.N.X.; Borges, F.H.; Lopes, N.M.D.; Simão, A.N.C.; et al. "Isoflavin-ß modifies muscle oxidative stress and prevents a thyrotoxicosis-induced loss of muscle mass in rats". Muscle and Nerve 56 5 (2017): 975-981. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017364722&partnerID=MN8TOARS.
10.1002/mus.25546
Padilha, C.S.; Marinello, P.C.; Galvão, D.A.; Newton, R.U.; Borges, F.H.; Frajacomo, F.; Deminice, R.. "Evaluation of resistance training to improve muscular strength and body composition in cancer patients undergoing neoadjuvant and adjuvant therapy: a meta-analysis". Journal of Cancer Survivorship 11 3 (2017): 339-349. http://www.scopus.com/inward/record.url?eid=2-s2.0-85008224690&partnerID=MN8TOARS.
10.1007/s11764-016-0592-x
Marinello, P.C.; da Silva, T.N.X.; Panis, C.; Neves, A.F.; Machado, K.L.; Borges, F.H.; Guarnier, F.A.; et al. "Mechanism of metformin action in MCF-7 and MDA-MB-231 human breast cancer cells involves oxidative stress generation, DNA damage, and transforming growth factor ß1 induction". Tumor Biology 37 4 (2016): 5337-5346. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946761772&partnerID=MN8TOARS.
10.1007/s13277-015-4395-x
Deminice, R.; Padilha, C.D.S.; Borges, F.; da Silva, L.E.C.M.; Rosa, F.T.; Robinson, J.L.; Cecchini, R.; Guarnier, F.A.; Frajacomo, F.T.. "Resistance exercise prevents impaired homocysteine metabolism and hepatic redox capacity in Walker-256 tumor-bearing male Wistar rats". Nutrition 32 10 (2016): 1153-1158. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973534393&partnerID=MN8TOARS.
10.1016/j.nut.2016.03.008
Deminice, R.; Cella, P.S.; Padilha, C.S.; Borges, F.H.; da Silva, L.E.C.M.; Campos-Ferraz, P.L.; Jordao, A.A.; et al. "Creatine supplementation prevents hyperhomocysteinemia, oxidative stress and cancer-induced cachexia progression in Walker-256 tumor-bearing rats". Amino Acids 48 8 (2016): 2015-2024. http://www.scopus.com/inward/record.url?eid=2-s2.0-84954485472&partnerID=MN8TOARS.
10.1007/s00726-016-2172-9
Borges, F.H.; Marinello, P.C.; Cecchini, A.L.; Blegniski, F.P.; Guarnier, F.A.; Cecchini, R.. "Oxidative and proteolytic profiles of the right and left heart in a model of cancer-induced cardiac cachexia". Pathophysiology 21 4 (2014): 257-265. http://www.scopus.com/inward/record.url?eid=2-s2.0-84912522747&partnerID=MN8TOARS.
10.1016/j.pathophys.2014.05.003

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2023/05/05	The role of oxidative stress in cardiac and skeletal function in ovariectomized rats with 6-hydroxydopamine-induced Parkinsonism and treated with estradiol	11º Congresso Paranaense de Ciências Biológicas Universidade Estadual de Londrina (Londrina, Brazil)
2023/05/05	Childhood-induced obesity causes endothelial dysfunction and arterial hypertension throughout life in Wistar rats	11º Congresso Paranaense de Ciências Biológicas Universidade Estadual de Londrina (Londrina, Brazil)
2023/05/04	The treatment with juçara pulp improves glucose uptake in pregnant rats of advanced age	11º Congresso Paranaense de Ciências Biológicas Universidade Estadual de Londrina (Londrina, Brazil)
2023/03/03	Cardiovascular parameters and electrocardiogram in ovariectomized rats induced to Parkinsonism and treated with estradiol	XXVII Simpósio Brasileiro de Fisiologia Cardiovascular Universidade Federal de Santa Catarina (Florianópolis, Brazil)
2023/03/02	Oxidative profile of the left ventricle in rats with 6-OHDA-induced parkinsonism treated with estradiol	XXVII Simpósio Brasileiro de Fisiologia Cardiovascular Universidade Federal de Santa Catarina (Florianópolis, Brazil)
2023/01/20	Parkinson and its advancements	I Curso de Verão em Ciências Fisiológicas Universidade Estadual de Londrina (Londrina, Brazil)
2019/05/22	Creatine supplementation exacerbates ethanol-induced hepatic damage in mice	III ISEP - International Symposium of Experimental Pathology (Londrina, Brazil)
2019/05/22	Free radical scavenger potential of Hylocereus undatus, Hylocereus costaricensis and Selenicereus megalanthus	III ISEP - International Symposium of Experimental Pathology (Londrina, Brazil)
2019/05/22	Hylocereus undatus seeds protects cell membrane from lipoperoxidation independently of iron chelation	III ISEP - International Symposium of Experimental Pathology (Londrina, Brazil)
2018/10/24	Clinical Oncology	Semana da Farmácia Universidade Filadélfia (Londrina, Brazil)
2018	O desenvolvimento tumoral leva a alterações na condução elétrica e edema pulmonar em ratos Wistar implantados com células de Walker-256	XIX Simpósio Internacional de Fisioterapia Cardiorrespiratória e Fisioterapia em Terapia Intensiva (Manaus, Brazil)
2018	Creatine supplementation exacerbates ethanol-induced hepatic steatosis and liver damage in mice	World Toxicologic Pathology Congress (São Paulo, Brazil)
2017	Alterações cardiopulmonares durante o desenvolvimento tumoral de células de Walker-256 em ratos Wistar	IX Congresso Sulbrasileiro de Fisioterapia Respiratória, Cardiovascular e em Terapia Intensiva (Curitiba, Brazil)
2016/04/26	Performance of pharmacist in clinical oncological activity	Simpósio de Farmácia Universidade Norte do Paraná (Arapongas, Brazil)
2016	Creatina previne a perda de massa muscular cardíaca e esquelética em ratos caquéticos induzidos por tumor de Walker-256	XVI Congresso de Ciências do Desporto e Educação Física dos Países de Língua Portuguesa (Porto, Portugal)
2016	Creatine supplementation increases liver oxidative stress and lipids accumulation in a model of murine alcoholic steatosis	I Internacional Symposium of Experimental Pathology (Londrina, Brazil)
2016	Creatine treatment modulates oxidative damage on left ventricle in Walker-256 tumor-bearing Rats	17th Internacional conference on Oxidative stress reduction, redox homeostasis and antioxidants (Paris, France)
2016	Creatine treatment modulates protein oxidative damage on left ventricle during neoplastic cachexia developed by Walker-256 tumor-bearing rats	17th Internacional conference on Oxidative stress reduction, redox homeostasis and antioxidants (Paris, France)
2016	Estresse oxidativo e sinalização na resistência à doxorrubicina em células de câncer de mama humano MCF-7 e MDA-MB-231	IX Congresso Franco Brasileiro de Oncologia (Rio de Janeiro, Brazil)
2016	O treinamento com exercício resistido previne a perda de peso, o aumento do estresse oxidativo muscular e o aumento da inflamação sistêmica em ratos com tumor de Walker-256	XVI Congresso de Ciências do Desporto e Educação Física dos Países de Língua Portuguesa (Porto, Portugal)
2016	Positive effects of resistance exercise training on cachexia-associated muscle waste, inflammation and oxidative stress in Walker-256 tumor-bearing rats	17th Internacional Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants (Paris, France)
2016	Resistente exercise training prevents cachexia-associated muscle wasting, attenuating systemic inflammation and muscle oxidative stress in Walker-256 tumor-bearing rats	17th Internacional Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants (Berlim, Germany)
2016	Right ventricle loss of function, modulated by oxidative stress and calpaan activity, is prevented by creatine supplementation in rats bearing Walker-256 tumor	9th Internacional Conference on Cachexia, Sarcopenia and Muscle Wasting (Berlim, Germany)
2016	O treinamento resistido atenua a caquexia do câncer em dois modelos experimentais de tumor sólidos	VI Congresso Brasileiro de Metabolismo, Nutrição e Exercício (Londrina, Brazil)
2016	Suplementação de creatina protege a perda de massa muscular em ratos com tumor de Walker-256 pela redução da inflamação sistêmica e estresse oxidativo muscular	VI Congresso Brasileiro de Metabolismo, Nutrição e Exercício Galoa (Londrina, Brazil)
2014	Efeito do treinamento resistido sobre a caquexia em ratos inoculados com tumor Walker-256	V Congresso Brasileiro de Metabolismo, Nutrição e Exercício (Londrina, Brazil)
2014	Envolvimento do estresse oxidativo na adaptação do músculo cardíaco em ratos portadores da forma sólida do tumor de Walker-256	II Bienal Internacional de Oncologia (Sao Paulo, Brazil)
2014	Metformina induz apontoes em células de adenocarcinoma mamário humano através do aumento de P53, TGF-B1 e da indução de estresse oxidativo celular	4o Congresso Paranaense de Ciências Biomédicas (Londrina, Brazil)
2014	Relação entre a carbonização de proteínas e a ativação da protelasse em ratos com tumor de Walker-256	XVII Simposio Brasileiro de Fisiologia Cardiovascular (Londrina, Brazil)

Event organisation

	Event name Type of event (Role)	Institution / Organization
2015/01/19 - 2015/01/23	Curso de Patologia Básica (2015/01/19 - 2015/01/19) Workshop (Co-organisor)	Universidade Estadual de Londrina, Brazil

Event participation

	Activity description Type of event	Event name Institution / Organization
2023/05/03 - 2033/05/05	Conference paper reviewer Congress	11º Congresso Paranaense de Ciências Biológicas Universidade Estadual de Londrina, Brazil
2023/02/03 - 2023/02/03	Conference paper reviewer Symposium	XII Simpósio de Patologia Experimental Universidade Estadual de Londrina, Brazil
2019/05/22 - 2019/05/24	Conference paper reviewer Symposium	III ISEP - International Symposium of Experimental Pathology Universidade Estadual de Londrina, Brazil
2017/10/25 - 2017/10/27	Conference paper reviewer Meeting	XXVI Encontro Anual de Iniciação Científica da UEL Universidade Estadual de Londrina, Brazil
2016 - 2016	I Internacional Symposium of Experimental Pathology Symposium
2016 - 2016	XVI Congresso de Ciências do Desporto e Educação Física dos Países de Língua Portuguesa Congress
2016 - 2016	17th Internacional conference on Oxidative stress reduction, redox homeostasis and antioxidants Congress
2016 - 2016	IX Congresso Franco Brasileiro de Oncologia Congress
2016 - 2016	9th Internacional Conference on Cachexia, Sarcopenia and Muscle Wasting Congress
2016 - 2016	VI Congresso Brasileiro de Metabolismo, Nutrição e Exercício Congress
2014 - 2014	V Congresso Brasileiro de Metabolismo, Nutrição e Exercício Congress
2014 - 2014	II Bienal Internacional de Oncologia Congress
2014 - 2014	4o Congresso Paranaense de Ciências Biomédicas Congress
2014 - 2014	XVII Simposio Brasileiro de Fisiologia Cardiovascular Symposium
2013 - 2013	VIII International Congress of Society for Free Radical Biology and Medicine Congress	Society for Free Radical Biology and Medicine
2013 - 2013	3o Congresso Paranaense de Ciências Biomédicas Congress
2013 - 2013	9th International conference on homocysteine and one-carbon metabolism Conference

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2022/10/20	Transgenerational evaluation of the effect of maternal exposure to phthalate mixtures on testicular and epididymal parameters of prepubertal and adult male rats (Thesis) Arguer	Ana Paula Franco Punhagui (PhD) Universidade Estadual de Londrina, Brazil
2018/01/09	Análise da capacidade antioxidante da Pitaya branca (Hylocereus undatus) (Thesis) Main arguer	Hannah Hamada Mendonça Lens (Other) Universidade Estadual de Londrina Centro de Ciências Biológicas, Brazil

Association member

	Society Organization name	Role
2014 - Current	Brazilian Society of Pharmacists in Oncology

Consulting

	Activity description	Institution / Organization
2017 - Current	Journal of Clinical & Experimental Oncology
2016 - Current	Internacional Journal of Sports Medicine

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2017/04/10 - Current	Oncology Pharmacology	Clinical Pharmacy (Postgraduate Certificate)	Centro Universitário Filadélfia, Brazil
2013 - Current	Pharmaceutical Chemistry	Pharmacy (Graduado)	Faculdade de Ensino Superior Dom Bosco, Brazil
2013 - Current	Clinical Biochemistry	Pharmacy (Graduado)	Faculdade de Ensino Superior Dom Bosco, Brazil
2013 - Current	Human Genetics	Pharmacy (Graduado)	Faculdade de Ensino Superior Dom Bosco, Brazil
2012/10/20 - 2012/10/20	Methodology of Higher Education	Criminalistics - Criminal Forensics (Postgraduate Certificate)	Insituto Keynes, Brazil

Journal scientific committee

	Journal title (ISSN)	Publisher
2020/05/20 - Current	British Journal of Nutrition
2017/04/09 - Current	Journal of Athletic Enhancement
2016/08/15 - Current	Internacional Journal of Sports Medicine

Other jury / evaluation

	Activity description	Institution / Organization
2014/05/08 - 2014/05/10	33o Concurso Público de Provas e Títulos para Provimento de Cargo de Professor de Ensino Superior na Unioeste	Universidade Estadual do Oeste do Paraná, Brazil

Distinctions

Award

2023	Honorable mention for best work and oral presentation in 11º Congresso Paranaense de Ciências Biomédicas
2018	3rd place in “Moderate Poster” category, in the “Animal Model Studies” area
2015	Honorable mention in the Experimental Nutrition Category, Brazilian Food Society and Nutrition