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Graça Soveral graduated in Pharmacy from the University of Lisbon and received her PhD in Pharmacy-Biochemistry from the same University, with all the experimental work conducted at Instituto de Tecnologia Química e Biológica (ITQB), NOVA University of Lisbon. She is Full Professor of Biochemistry and Vice-Dean of the Faculty of Pharmacy, University of Lisbon. She is Head of the Membrane Transporters in Health and Disease laboratory at the Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon. Her scientific interests are centered on the study of membrane transport in biological systems, investigating mechanisms underlying transporter defects that may lead to disease. Her group is focused on membrane water channels (aquaporins) as targets for drug action, identifying mechanisms of aquaporin regulation, and discovering modulators for diagnostic and therapeutic applications. She has contributed to unveiling the crucial role of aquaporins in obesity, inflammation, and cancer, paving the way for the development of novel pharmacological approaches. Soveral has published more than 100 indexed peer-reviewed publications, which received more than 3000 citations (Scopus: h-index 33). In addition, she (co)authored 5 articles in Portuguese scientific journals, 5 book chapters, 2 books as editor (published by CRC and Frontiers), and filled 1 international patent. She is Past-President of the Portuguese Biochemical Society (SPB), treasurer of the Portuguese Biophysical Society (SPBf), and is currently Chair of FEBS (Federation of European Biochemical Societies). Soveral has supervised nearly 30 PhD/MSc students and postdoctoral fellows. She has been an invited speaker at top-tier international conferences and served as a reviewer and panel chair on national and international grant review boards.
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Identification

Personal identification

Full name
Maria da GRAÇA Tavares Rebelo de SOVERAL Rodrigues

Citation names

  • Soveral, Graça
  • Soveral, G.

Author identifiers

Ciência ID
2114-D43A-FDD9
ORCID iD
0000-0001-8487-110X
Google Scholar ID
https://scholar.google.com/citations?user=sxaKHUwAAAAJ&hl=en
Researcher Id
L-1550-2013
Scopus Author Id
6602417900

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Medical and Health Sciences - Health Sciences - Nutrition, Dietetics
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Biophysics
  • Natural sciences - Biological Sciences - Cell Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Advanced (C1) Advanced (C1) Upper intermediate (B2) Advanced (C1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1)
Education
Degree Classification
2011
Concluded
 Pharmacy (Título de Agregado)
Major in Speciality Biochemistry
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Transporte Membranar e Regulação: O Papel das Aquaporinas na Regulação do Volume Celular" (THESIS/DISSERTATION)
 Summa Cum Laude
1995
Concluded
 Pharmacy (Doutoramento)
Major in Especialidade: Biochemistry
Universidade de Lisboa, Portugal
"Comportamento Osmótico de Vesículas da Membrana Apical do Tubulo Proximal do Rim de Coelho" (THESIS/DISSERTATION)
 Summa Cum Laude
1982
Concluded
 Pharmacy (Licenciatura)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"n/a" (THESIS/DISSERTATION)
 14 Valores
Affiliation

Science

Category
Host institution 		Employer
2012/01/01 - Current Principal Investigator (Research) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
1995 - 2011 Invited Principal Investigator (Research) Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2022/01/03 - Current Full Professor (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2012/06/01 - 2021/12/31 Associate Professor (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal
1995 - 2011 Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal
1987/07/01 - 1995/06/06 Assistant (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal
1983 - 1987 Trainee Assistant (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal

Positions / Appointments

Category
Host institution 		Employer
2010/10/01 - Current Vice-Dean Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/07/01 - 2020/12/31 Head of Department Biochemistry and Human Biology Universidade de Lisboa, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014 - 2018 Member - Scientific Council Universidade de Lisboa, Portugal
2004 - 2010 Vice-President of the Pedagogical Council Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal

Others

Category
Host institution 		Employer
1982/08/01 - 1986/07/31 Técnica Superior de Análises Clínicas Centro de Urgência Laboratorial, Urgilab, Lisboa, Portugal
Projects

Grant

Designation Funders
2023 - 2026 Aquaporin-9 Immuno-Therapy: a new strategy for reducing inflammation
2022.06601.PTDC
 Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2018/10 - 2021/09 AQUA3-4MEL - Targeting aquaporin-3 as a novel therapeutic approach for melanoma
PTDC/BTM-SAL/28977/2017
Principal investigator
Fundação para a Ciência e a Tecnologia
Ongoing
2018 - 2021 PAINSpot - Deal with PAINS: strategies to spot membrane modulators
PTBC/BIA-BFS/28419/2017
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2013/06 - 2016/12 Oocyte membrane properties and calcium homeostasis: opening new doors for improving cryopreservation
PTDC/CVT REP/2863/2012
Principal investigator
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2012 - 2014 AQUAGLY - FRA C-line as aquaglyceroporin inhibitors
AQUAGLY
Principal investigator
FRAMELCO, BV.
Concluded
2012 - 2014 AQUAGLY - FRA C-line as aquaglyceroporin inhibitors
AQUAGLY
 FRAMELCO, BV.
2009/01 - 2013/03 AQUAVITIS - Understanding water transport in Vitis vinifera: biochemical characterization of aquaporins upon their heterologous expression in yeast
PTDC/AGR-AAM/099154/2008
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005 - 2010 Freezing and dehydration of yeasts and grape berries: a role for mediated water fluxes
POCTI/AGR/57403/2004
Principal investigator
Fundação para a Ciência e a Tecnologia
Concluded
2002 - 2006 Biologic Effects of conjugated linoleic acid isomers (CLA) in the Portuguese population
POCTI/2002/44750
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
1999 - 2003 Biogenesis and function of CFTR protein with different mutations: molecular basis for cystic fibrosis clinical and therapeutic heterogeneity?
POCTI/1999/M.G.I./35737
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
1997 - 1999 Trans-epithelial Ion Transport in the gastrointestinal tract – correlation between function and channel electrophysiology"
PRAXIS PCNA/C/BIA/183/96
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
1997 - 1999 Valproic Acid Toxicity: mechanisms of cellular oxidation inhibition
PRAXIS/PSAU/CSAU/27/96
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
1997 - 1999 Valproic Acid Toxicity: mechanisms of cellular oxidation inhibition
PRAXIS/PSAU/CSAU/27/96
 N/A
1995 - 1999 Using epithelia as toxicity sensors
PRAXIS/2/2.1/BIO/1159/95
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book
  1. Soveral, Graça; Indiveri, Cesare. Membrane Transporters and Channels as Targets for Drugs. Frontiers Media SA. 2020.
    Published • 10.3389/978-2-88963-357-9
  2. Soveral, Graça; Casini, Angela. Aquaporins in health and disease: New molecular targets for drug discovery. 2016.
    10.1201/b19017
Book chapter
  1. da Silva, Inês Vieira; Soveral, Graça. "Aquaporins in Obesity". In Advances in Experimental Medicine and Biology, 227-238. Springer Netherlands, 2017.
    Published • 10.1007/978-94-024-1057-0_15
  2. Madeira, Ana; Moura, Teresa; Soveral, Graça. "Aquaporin Functional Detection: Basic Concepts on Water and Solute Permeation". In Aquaporins in Health and Disease, 3-17. United States: CRC Press, 2016.
    Published • 10.1201/b19017-3
  3. Sabir, Farzana; Prista, Catarina; Madeira, Ana; Moura, Teresa; Loureiro-Dias, Maria C.; Soveral, Graça. "Water Transport in Yeasts". In Advances in Experimental Medicine and Biology, 107-124. Springer International Publishing, 2016.
    Published • 10.1007/978-3-319-25304-6_5
  4. Soveral, Graça. "Mecanismos Bioquímicos". In NUTRACÊUTICOS E ALIMENTOS FUNCIONAIS. Portugal: Lidel – Edições Técnicas, Lda, 2010.
    Published
Conference abstract
  1. Da Silva, I.V.; Matos, A.; Pereira Da Silva, A.; Santos, A.; Portelinha, A.; José Areias, M.; Soveral, G.; Rebelo, I.; Bicho, M.. "CARDIOVASCULAR RISK MAY BE PREDICTED BY P22PHOX AND NITRIC OXIDE SYNTHASE POLYMORPHISMS IN WOMEN WITH PREVIOUS PREGNANCY HYPERTENSION". 2019.
    10.1097/01.hjh.0000573056.97903.4d
  2. Bernal-Marti´nez, Juan. "CFTR modulates aquaporin-mediated glycerol permeability in mouse sertoli cells". Paper presented in XX Congreso de la Sociedad Española de Histología e Ingeniería Tisular, VIII International Congress of Histology and Tissue Engineering, VI Congreso Iberoamericano de Histología, Murcia, 2019.
    Published • 10.1063/1.1811852
  3. Soveral, Graça. "Is there a role for P2Y2 receptors in bovine oocyte cryopreservation?". Paper presented in REPRODUCTION IN DOMESTIC ANIMALS, 2019.
  4. Soveral, Graça. "Screening polyoxometalates as aquaporin inhibitors for cancer therapeutics". Paper presented in FEBS OPEN BIO, 2019.
    Published
  5. Abas, R; Wozniak, M; Herbert, K. "Aquaporin-3 is involved in NLRP3-inflammasome priming and activation". Paper presented in EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2019.
    Published • 10.1136/heartjnl-2016-310696.23
  6. Soveral, Graça. "Aquaporins as sensors for turgor and cell volume regulation". Paper presented in FEBS OPEN BIO, 2018.
    Published
  7. Soveral, Graça. "Aquaporins and hypomethylation in endothelia: implications in cardiovascular disease". Paper presented in FEBS OPEN BIO, 2018.
    Published
  8. Soveral, Graça. "AQP5-mediated hydrogen peroxide permeation is altered by nutritional compounds and induces cell resistance". Paper presented in FEBS OPEN BIO, 2018.
    Published
  9. Soveral, Graça. "Role of ghrelin and glucagon-like peptide-1 in aquaporin-7-induced insulin secretion and triacylglycerol accumulation in rat beta-cells". Paper presented in EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2018.
    Published
  10. Soveral, Graça. "Insights on aquaporins involvement in obesity-induced inflammation in pancreatic beta-cells". Paper presented in FREE RADICAL BIOLOGY AND MEDICINE, 2018.
    Published • 10.1016/j.freeradbiomed.2018.04.203
  11. Soveral, Graça. "Short-term regulation of Aquaporin-5 by combined phosphorylation and pH". Paper presented in FREE RADICAL BIOLOGY AND MEDICINE, 2018.
    Published • 10.1016/j.freeradbiomed.2018.04.446
  12. Soveral, Graça. "Human AQP5 facilitates hydrogen peroxide permeation and improves cell resistance to oxidative stress". Paper presented in FREE RADICAL BIOLOGY AND MEDICINE, 2018.
    Published • 10.1016/j.freeradbiomed.2018.04.233
  13. Soveral, Graça. "Aquaporins are novel targets for obesity and cancer". Paper presented in ANNALS OF MEDICINE, 2018.
    Published
  14. Soveral, Graça. "Nutritional profile of green seeds from different species of legumes". Paper presented in ANNALS OF MEDICINE, 2018.
    Published
  15. Soveral, Graça. "Biophysical assessment of endothelial aquaporins as water and glycerol channels". Paper presented in EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2017.
    Published
  16. Soveral, Graça. "Role of aquaporins in hydrogen peroxide permeation and oxidative stress". Paper presented in EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2017.
    Published
  17. Soveral, Graça. "Rat aquaporin-5 is pH-gated induced by phosphorylation". Paper presented in EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2017.
    Published
  18. Soveral, Graça. "Roles of Aquaporins in health and disease: promising targets for drug discovery". Paper presented in EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2017.
    Published
  19. Rodriguez, A.; Moreno, N. R.; Balaguer, I.; Mendez-Gimenez, L.; Becerril, S.; Catalan, V.; Gomez-Ambrosi, J.; et al. "Leptin replacement improves the non-alcoholic fatty liver of ob/ob mice partly through the restoration of the altered adipose and hepatic expression of aquaglyceroporins". Paper presented in EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2016.
    Published
  20. Soveral, Graça. "Effect of different cocktails of cryoprotectants and calcium on bovine oocyte membrane permeability and cryosurvival.". Paper presented in REPRODUCTION IN DOMESTIC ANIMALS, 2016.
    Published
  21. Soveral, Graça. "Effect of P2Y2 receptors modulation on bovine oocyte cryosurvival". Paper presented in REPRODUCTION IN DOMESTIC ANIMALS, 2016.
    Published
  22. Soveral, Graça. "Aquaporin inhibition by gold compounds: new insights.". Paper presented in J. Biol. Inorg. Chem., 2014.
    Published
  23. Soveral, Graça. "Detection of pancreatic cancer by ATR-FTIR spectroscopy.". Paper presented in HPB, 2014.
    Published
  24. Soveral, Graça. "Functional characterization of PIP and TIP grapevine aquaporins by heterologous expression in Saccharomyces cerevisiae.". Paper presented in YEAST, 2013.
    Published
  25. Soveral, Graça. "Effect of a gold-based compound on AQP3 permeability and cell proliferation of tumor cells.". Paper presented in Eur. Biophys. J., 2013.
    Published
  26. Soveral, Graça. "Screening aquaporin modulators by heterologous expression in yeast.". Paper presented in Eur. Biophys. J., 2013.
    Published
  27. Soveral, Graça. "Functional characterization of mammalian aquaporin-7 and aquaporin-3 by heterologous expression in yeast.". Paper presented in Eur. Biophys. J., 2013.
    Published
  28. Soveral, Graça. "Biophysical characterization of AQP7 in adipocytes.". Paper presented in Eur. Biophys. J., 2013.
    Published
  29. Soveral, Graça. "Mammals aquaporin modulators: screening by heterologous expression in Saccharomyces cerevisiae.". Paper presented in FEBS J., 2013.
    Published
  30. Soveral, Graça. "Aquaporin inhibition by a gold-based compound.". Paper presented in FEBS J., 2012.
    Published
  31. Soveral, Graça. "The gold-based compound Auphen affects proliferation rate of AQP3 expressing cells.". Paper presented in FEBS J., 2012.
    Published
  32. Soveral, Graça. "Biopharmaceutics Drug Disposition Classification System (BDDCS) and the role of P-gp in intestinal transport of Class 1 drug verapamil.". Paper presented in Drug Information Journal, 2010.
    Published
  33. Dias, Catarina; Testa, Bernard; Soveral, Graça; Constantino, Luís; Dias, Mário. "The effect of xenobiotics on rat liver alcohol dehydrogenase activity or how medicines can affect the metabolism of alcohol". 2009.
  34. Soveral, Graça. "Aquaporins as cell volume regulators: how membrane tension affects water permeability.". Paper presented in Eur. Biophys. J., 2009.
    Published
  35. Soveral, Graça. "Characterization of a Vitis vinifera CV Touriga Nacional TIP aquaporin using Saccharomyces cerevisiae heterologous expression system.". Paper presented in Australian Journal of Grape and Wine Research, 2008.
    Published
  36. Soveral, Graça. "The human carnitine acylcarnitine translocase (hCACT): Strategies for its heterologous expression, purification and crystallization.". Paper presented in J. Inherited Metabolic Disease, 2007.
    Published
  37. Soveral, Graça. "Antiobesity drugs and diet products use pattern in a Portuguese sample.". Paper presented in Pharm. World Science, 2005.
    Published
  38. Soveral, Graça. "Bacterial overexpression of human carnitine acylcarnitine translocase (CACT): Solubilization and purification by NI2+-affinity chromatography.". Paper presented in J. Inherited Metabolic Disease, 2004.
    Published
  39. Soveral, Graça. "Pyruvate uptake is inhibited by valproic acid and 3-keto-valproic acid in inverted submitochondrial vesicles.". Paper presented in J. Inherited Metabolic Disease, 2004.
    Published
  40. Soveral, Graça. "Studies on Water Transport and CFTR channel in membrane vesicles from two different cell lines.". Paper presented in . Eur. Biophys. J. Biophy., 2003.
    Published
  41. Soveral, Graça. "Different pathways for water permeation through two volume transporter epithelia.". Paper presented in Biophysical Journal, 2000.
    Published
  42. Soveral, Graça. "Volume transport epithelia: different pathways for water permeation.". Paper presented in J. Physiology – London, 2000.
    Published
Journal article
  1. da Silva, Inês V.; Pimpão, Catarina; Paccetti-Alves, Inês; Thomas, Sophie R.; Barateiro, Andreia; Casini, Angela; Soveral, Graça. "Blockage of aquaporin-3 peroxiporin activity by organogold compounds affects melanoma cell adhesion, proliferation and migration". The Journal of Physiology (2024): http://dx.doi.org/10.1113/jp284155.
    10.1113/jp284155
  2. Paccetti-Alves, Inês; Batista, Marta S. P.; Pimpão, Catarina; Victor, Bruno L.; Soveral, Graça. "Unraveling the Aquaporin-3 Inhibitory Effect of Rottlerin by Experimental and Computational Approaches". International Journal of Molecular Sciences 24 6 (2023): 6004. http://dx.doi.org/10.3390/ijms24066004.
    10.3390/ijms24066004
  3. da Silva, I.V.; Soveral, G.. "Aquaporins in Obesity". Advances in experimental medicine and biology 1398 (2023): 289-302. http://www.scopus.com/inward/record.url?eid=2-s2.0-85147168393&partnerID=MN8TOARS.
    10.1007/978-981-19-7415-1_20
  4. Frühbeck, G.; Méndez-Giménez, L.; Becerril, S.; Ramírez, B.; Hernández-Pardos, A.W.; Cienfuegos, J.A.; Valentí, V.; et al. "Increased Aquaporin-7 Expression Is Associated with Changes in Rat Brown Adipose Tissue Whitening in Obesity: Impact of Cold Exposure and Bariatric Surgery". International Journal of Molecular Sciences 24 4 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85149012232&partnerID=MN8TOARS.
    10.3390/ijms24043412
  5. Da Silva, I.V.; Coelho, D.; Prates, J.A.M.; Soveral, G.; Lopes, P.A.. "Tissue-Specific Variation in Aquaporins and Cytokines Transcriptional Profiles in Piglets being LPS Challenged". Frontiers in Bioscience - Landmark 28 6 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85163618180&partnerID=MN8TOARS.
    10.31083/j.fbl2806126
  6. Mlinaric, M.; Lucic, I.; Milkovic, L.; da Silva, I.V.; Tartaro Bujak, I.; Musani, V.; Soveral, G.; Cipak Gašparovic, A.. "AQP3-Dependent PI3K/Akt Modulation in Breast Cancer Cells". International Journal of Molecular Sciences 24 9 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85159353909&partnerID=MN8TOARS.
    10.3390/ijms24098133
  7. Lopes, P.A.; Fonseca, E.; da Silva, I.V.; Vigia, E.; Paulino, J.; Soveral, G.. "Aquaporins Transcripts with Potential Prognostic Value in Pancreatic Cancer". Genes 14 9 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85172797108&partnerID=MN8TOARS.
    10.3390/genes14091694
  8. Pimpão, C.; Wragg, D.; da Silva, I.V.; Casini, A.; Soveral, G.. "Aquaglyceroporin Modulators as Emergent Pharmacological Molecules for Human Diseases". Frontiers in Molecular Biosciences 9 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85124894543&partnerID=MN8TOARS.
    10.3389/fmolb.2022.845237
  9. Ribeiro, J.C.; Bernardino, R.L.; Carrageta, D.F.; Soveral, G.; Calamita, G.; Alves, M.G.; Oliveira, P.F.. "CFTR modulates aquaporin-mediated glycerol permeability in mouse Sertoli cells". Cellular and Molecular Life Sciences 79 12 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85141860389&partnerID=MN8TOARS.
    10.1007/s00018-022-04619-1
  10. Silva, P.M.; da Silva, I.V.; Sarmento, M.J.; Silva, Í.C.; Carvalho, F.A.; Soveral, G.; Santos, N.C.. "Aquaporin-3 and Aquaporin-5 Facilitate Migration and Cell-Cell Adhesion in Pancreatic Cancer by Modulating Cell Biomechanical Properties". Cells 11 8 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85128190004&partnerID=MN8TOARS.
    10.3390/cells11081308
  11. da Silva, I.V.; Gullette, S.; Florindo, C.; Huang, N.K.; Neuberger, T.; Ross, A.C.; Soveral, G.; Castro, R.. "The Effect of Nutritional Ketosis on Aquaporin Expression in Apolipoprotein E-Deficient Mice: Potential Implications for Energy Homeostasis". Biomedicines 10 5 (2022): 1159-1159. http://www.scopus.com/inward/record.url?eid=2-s2.0-85131006042&partnerID=MN8TOARS.
    10.3390/biomedicines10051159
  12. da Silva, I.V.; Garra, S.; Calamita, G.; Soveral, G.. "The Multifaceted Role of Aquaporin-9 in Health and Its Potential as a Clinical Biomarker". Biomolecules 12 7 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85132821069&partnerID=MN8TOARS.
    10.3390/biom12070897
  13. da Silva, Inês Vieira; Santos, Ana Carolina; Matos, Andreia; Pereira da Silva, Alda; Soveral, Graça; Rebelo, Irene; Bicho, Manuel. "Association of Aquaporin-3, Aquaporin-7, NOS3 and CYBA polymorphisms with hypertensive disorders in women". Pregnancy Hypertension 24 (2021): 44-49. http://dx.doi.org/10.1016/j.preghy.2021.02.008.
    10.1016/j.preghy.2021.02.008
  14. Sabir, Farzana; Zarrouk, Olfa; Noronha, Henrique; Loureiro-Dias, Maria C.; Soveral, Graça; Gerós, Hernâni; Prista, Catarina. "Grapevine aquaporins: Diversity, cellular functions, and ecophysiological perspectives". Biochimie (2021): http://dx.doi.org/10.1016/j.biochi.2021.06.004.
    10.1016/j.biochi.2021.06.004
  15. da Silva, Inês V.; Silva, Andreia G.; Pimpão, Catarina; Soveral, Graça. "Skin aquaporins as druggable targets: Promoting health by addressing the disease". Biochimie (2021): http://dx.doi.org/10.1016/j.biochi.2021.05.019.
    10.1016/j.biochi.2021.05.019
  16. Agata Wawrzkiewicz-Jalowiecka; Anna Lalik; Graça Soveral. "Recent Update on the Molecular Mechanisms of Gonadal Steroids Action in Adipose Tissue". International Journal of Molecular Sciences 22 10 (2021): 5226-5226. https://doi.org/10.3390/ijms22105226.
    10.3390/ijms22105226
  17. Jacinta O. Pinho; Inês V. da Silva; Joana D. Amaral; Cecília M.P. Rodrigues; Angela Casini; Graça Soveral; Maria Manuela Gaspar. "Therapeutic potential of a copper complex loaded in pH-sensitive long circulating liposomes for colon cancer management". International Journal of Pharmaceutics (2021): https://doi.org/10.1016/j.ijpharm.2021.120463.
    10.1016/j.ijpharm.2021.120463
  18. Inês V. da Silva; Graça Soveral. "Aquaporins in Immune Cells and Inflammation: New Targets for Drug Development". International Journal of Molecular Sciences 22 4 (2021): 1845-1845. https://doi.org/10.3390/ijms22041845.
    10.3390/ijms22041845
  19. Inês V. da Silva; Courtney A. Whalen; Floyd J. Mattie; Cristina Florindo; Neil K. Huang; Sandra G. Heil; Thomas Neuberger; et al. "An Atherogenic Diet Disturbs Aquaporin 5 Expression in Liver and Adipocyte Tissues of Apolipoprotein E-Deficient Mice: New Insights into an Old Model of Experimental Atherosclerosis". Biomedicines 9 2 (2021): 150-150. https://doi.org/10.3390/biomedicines9020150.
    10.3390/biomedicines9020150
  20. Inês Vieira da Silva; Bárbara P. Soares; Catarina Pimpão; Rui M. A. Pinto; Teresa Costa; João P. B. Freire; Etienne Corrent; et al. "Glutamine and cystine-enriched diets modulate aquaporins gene expression in the small intestine of piglets". PLOS ONE 16 1 (2021): e0245739-e0245739. https://doi.org/10.1371%2Fjournal.pone.0245739.
    10.1371/journal.pone.0245739
  21. Pimpão, C.; Wragg, D.; Bonsignore, R.; Aikman, B.; Pedersen, P.A.; Leoni, S.; Soveral, G.; Casini, A.. "Mechanisms of irreversible aquaporin-10 inhibition by organogold compounds studied by combined biophysical methods and atomistic simulations". Metallomics : integrated biometal science 13 9 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85116172061&partnerID=MN8TOARS.
    10.1093/mtomcs/mfab053
  22. Gašparovic, A.C.; Milkovic, L.; Rodrigues, C.; Mlinaric, M.; Soveral, G.. "Peroxiporins are induced upon oxidative stress insult and are associated with oxidative stress resistance in colon cancer cell lines". Antioxidants 10 11 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85119585534&partnerID=MN8TOARS.
    10.3390/antiox10111856
  23. Soveral, G.. "The key role of aquaporins in animals and plants". Biochimie (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85111264655&partnerID=MN8TOARS.
    10.1016/j.biochi.2021.07.007
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  83. Estudante, M.; Morais, J.G.; Soveral, G.; Benet, L.Z.. "Intestinal drug transporters: An overview". Advanced Drug Delivery Reviews 65 10 (2013): 1340-1356. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885390032&partnerID=MN8TOARS.
    10.1016/j.addr.2012.09.042
  84. De Almeida, A.; Oliveira, B.L.; Correia, J.D.G.; Soveral, G.; Casini, A.. "Emerging protein targets for metal-based pharmaceutical agents: An update". Coordination Chemistry Reviews 257 19-20 (2013): 2689-2704. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882843820&partnerID=MN8TOARS.
    10.1016/j.ccr.2013.01.031
  85. Dias, C.; Testa, B.; Soveral, G.; Dias, M.; Constantino, L.. "Screening of the inhibitory effect of xenobiotics on alcohol metabolism using S9 rat liver fractions". Toxicology in Vitro 26 7 (2012): 1177-1180. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866048147&partnerID=MN8TOARS.
    10.1016/j.tiv.2012.06.011
  86. Leitão, L.; Prista, C.; Moura, T.F.; Loureiro-Dias, M.C.; Soveral, G.. "Grapevine aquaporins: Gating of a tonoplast intrinsic protein (TIP2;1) by cytosolic pH". PLoS ONE 7 3 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84858063921&partnerID=MN8TOARS.
    10.1371/journal.pone.0033219
  87. Martins, A.P.; Marrone, A.; Ciancetta, A.; Cobo, A.G.; Echevarría, M.; Moura, T.F.; Re, N.; Casini, A.; Soveral, G.. "Targeting aquaporin function: Potent inhibition of aquaglyceroporin-3 by a gold-based compound". PLoS ONE 7 5 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84862094229&partnerID=MN8TOARS.
    10.1371/journal.pone.0037435
  88. Martins, A.P.; Lopes, P.A.; Madeira, M.S.; Martins, S.V.; Santos, N.C.; Moura, T.F.; Prates, J.A.M.; Soveral, G.. "Differences in lipid deposition and adipose membrane biophysical properties from lean and obese pigs under dietary protein restriction". Biochemical and Biophysical Research Communications 423 1 (2012): 170-175. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862693223&partnerID=MN8TOARS.
    10.1016/j.bbrc.2012.05.108
  89. Martins, A.P.; Lopes, P.A.; Costa, A.S.H.; Martins, S.V.; Santos, N.C.; Prates, J.A.M.; Moura, T.F.; Soveral, G.. "Differential mesenteric fat deposition in bovines fed on silage or concentrate is independent of glycerol membrane permeability". Animal 5 12 (2011): 1949-1956. http://www.scopus.com/inward/record.url?eid=2-s2.0-80955160624&partnerID=MN8TOARS.
    10.1017/S1751731111001091
  90. Campos, E.; Moura, T.F.; Oliva, A.; Leandro, P.; Soveral, G.. "Lack of Aquaporin 3 in bovine erythrocyte membranes correlates with low glycerol permeation". Biochemical and Biophysical Research Communications 408 3 (2011): 477-481. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955766444&partnerID=MN8TOARS.
    10.1016/j.bbrc.2011.04.057
  91. Abreu-Rodríguez, I.; Sánchez Silva, R.; Martins, A.P.; Soveral, G.; Toledo-Aral, J.J.; López-Barneo, J.; Echevarría, M.. "Functional and transcriptional induction of aquaporin-1 gene by hypoxia; analysis of promoter and role of HIF-1a". PLoS ONE 6 12 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-82955194935&partnerID=MN8TOARS.
    10.1371/journal.pone.0028385
  92. Soveral, G.; Prista, C.; Moura, T.F.; Loureiro-Dias, M.C.. "Yeast water channels: An overview of orthodox aquaporins". Biology of the Cell 103 1 (2011): 35-54. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650785077&partnerID=MN8TOARS.
    10.1042/BC20100102
  93. Soveral, Graça; Trincão, J.; Moura, Teresa F.. "Aquaporins: membrane channels for water transport.". Canal BQ (Revista online da Sociedade Portuguesa de Bioquímica) 7 (2011): 36-43.
  94. Martins, A.P.; Lopes, P.A.; Martins, S.V.; Madeira, A.; Santos, N.C.; Prates, J.A.M.; Moura, T.F.; Soveral, G.. "Conjugated linoleic acid reduces permeability and fluidity of adipose plasma membranes from obese Zucker rats". Biochemical and Biophysical Research Communications 398 2 (2010): 199-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955057876&partnerID=MN8TOARS.
    10.1016/j.bbrc.2010.06.059
  95. Madeira, A.; Leitão, L.; Soveral, G.; Dias, P.; Prista, C.; Moura, T.; Loureiro-Dias, M.C.. "Effect of ethanol on fluxes of water and protons across the plasma membrane of Saccharomyces cerevisiae". FEMS Yeast Research 10 3 (2010): 252-258. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950873912&partnerID=MN8TOARS.
    10.1111/j.1567-1364.2010.00607.x
  96. Soveral, G.; Martins, A.P.; Martins, S.V.; Lopes, P.A.; Alfaia, C.M.; Prates, J.A.M.; Moura, T.F.. "Effect of dietary conjugated linoleic acid isomers on water and glycerol permeability of kidney membranes". Biochemical and Biophysical Research Communications 383 1 (2009): 108-112. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349163234&partnerID=MN8TOARS.
    10.1016/j.bbrc.2009.03.136
  97. Aires, C.C.P.; Soveral, G.; Luís, P.B.M.; ten Brink, H.J.; de Almeida, I.T.; Duran, M.; Wanders, R.J.A.; Silva, M.F.B.. "Pyruvate uptake is inhibited by valproic acid and metabolites in mitochondrial membranes". FEBS Letters 582 23-24 (2008): 3359-3366. http://www.scopus.com/inward/record.url?eid=2-s2.0-53049098697&partnerID=MN8TOARS.
    10.1016/j.febslet.2008.08.028
  98. Soveral, G.; Madeira, A.; Loureiro-Dias, M.C.; Moura, T.F.. "Membrane tension regulates water transport in yeast". Biochimica et Biophysica Acta - Biomembranes 1778 11 (2008): 2573-2579. http://www.scopus.com/inward/record.url?eid=2-s2.0-54049090340&partnerID=MN8TOARS.
    10.1016/j.bbamem.2008.07.018
  99. Mendes, L.; Castro, Matilde; Soveral, Graça. "A nutrição da mãe influencia a composição do leite materno?". Revista da APNEP 2 (2008): 73.
    Published
  100. Martins, S.V.; Lopes, P.A.; Alfaia, C.M.; Ribeiro, V.S.; Guerreiro, T.V.; Fontes, C.M.G.A.; Castro, M.F.; Soveral, G.; Prates, J.A.M.. "Contents of conjugated linoleic acid isomers in ruminant-derived foods and estimation of their contribution to daily intake in Portugal". British Journal of Nutrition 98 6 (2007): 1206-1213. http://www.scopus.com/inward/record.url?eid=2-s2.0-36649008513&partnerID=MN8TOARS.
    10.1017/S0007114507781448
  101. Soveral, G.; Madeira, A.; Loureiro-Dias, M.C.; Moura, T.F.. "Water transport in intact yeast cells as assessed by fluorescence self-quenching". Applied and Environmental Microbiology 73 7 (2007): 2341-2343. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247520064&partnerID=MN8TOARS.
    10.1128/AEM.02519-06
  102. Luís, P.B.M.; Ruiter, J.P.N.; Aires, C.C.P.; Soveral, G.; Tavares de Almeida, I.; Duran, M.; Wanders, R.J.A.; Silva, M.F.B.. "Valproic acid metabolites inhibit dihydrolipoyl dehydrogenase activity leading to impaired 2-oxoglutarate-driven oxidative phosphorylation". Biochimica et Biophysica Acta - Bioenergetics 1767 9 (2007): 1126-1133. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548187167&partnerID=MN8TOARS.
    10.1016/j.bbabio.2007.06.007
  103. Soveral, G.; Veiga, A.; Loureiro-Dias, M.C.; Tanghe, A.; Van Dijck, P.; Moura, T.F.. "Water channels are important for osmotic adjustments of yeast cells at low temperature". Microbiology 152 5 (2006): 1515-1521. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646832951&partnerID=MN8TOARS.
    10.1099/mic.0.28679-0
  104. Mendes, Lino; Castro, Matilde; Soveral, Graça. "Leite materno e o mercúrio". Boletim da APNEP 9 (2006): 35-40.
    Published
  105. Mendes, Lino; Rodrigues, Carla; Castro, Matilde; Soveral, Graça. "Essential mineral and toxic elements present in the tea soft drink.". Electron. J. Environ. Agric. Food Chem. 5 (2006): 1624-1628.
    Published
  106. Soveral, Graça; Lopes, F.; Ferreira, C.; Cabrita, José. "Estilo de vida e obesidade em adolescentes da região de Lisboa". Rev. Lusófona de Ciências e Tecnologias da Saúde 2 (2005): 109-115.
    Published
  107. Conceição, T.; Faria, N.; Pimentel, M.; Soveral, G.; Duarte, A.; Lito, L.M.; Melo Cristino, J.; Salgado, M.J.. "New Chromosomal AmpC ß-Lactamase in Enterobacter cloacae [3]". Antimicrobial Agents and Chemotherapy 48 4 (2004): 1437-1437. http://www.scopus.com/inward/record.url?eid=2-s2.0-18244426114&partnerID=MN8TOARS.
    10.1128/AAC.48.4.1437.2004
  108. Barroso, H.; Freitas-Vieira, A.; Lito, L.M.; Melo Cristino, J.; Salgado, M.J.; Ferreira Neto, H.; Sousa, J.C.; et al. "Survey of Klebsiella pneumoniae producing extended-spectrum ß-lactamases at a Portuguese hospital: TEM-10 as the endemic enzyme". Journal of Antimicrobial Chemotherapy 45 5 (2000): 611-616. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034015848&partnerID=MN8TOARS.
  109. Alves, P.; Soveral, G.; Macey, R.I.; Moura, T.F.. "Osmotic equilibrium and elastic properties of eel intestinal vesicles". Journal of Membrane Biology 171 2 (1999): 171-176. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033568268&partnerID=MN8TOARS.
    10.1007/s002329900568
  110. Alves, P.; Soveral, G.; Macey, R.I.; Moura, T.F.. "Kinetics of water transport in eel intestinal vesicles". Journal of Membrane Biology 171 2 (1999): 177-182. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033568269&partnerID=MN8TOARS.
    10.1007/s002329900569
  111. Soveral, G.; Macey, R.I.; Moura, T.F.. "Water permeability of brush border membrane vesicles from kidney proximal tubule". Journal of Membrane Biology 158 3 (1997): 219-228. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030740837&partnerID=MN8TOARS.
    10.1007/s002329900259
  112. Soveral, G.; Macey, R.I.; Moura, T.F.. "Membrane stress causes inhibition of water channels in brush border membrane vesicles from kidney proximal tubule". Biology of the Cell 89 5-6 (1997): 275-282. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031457959&partnerID=MN8TOARS.
    10.1016/S0248-4900(97)83379-5
  113. Soveral, G.; Macey, R.I.; Moura, T.F.. "Mechanical properties of brush border membrane vesicles from kidney proximal tubule". Journal of Membrane Biology 158 3 (1997): 209-217. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030840650&partnerID=MN8TOARS.
    10.1007/s002329900258
  114. Soveral, Graça; Santos, M. H.. "Teores de Ácido N-acetilneuramínico em crianças e adultos normais". Rev. Port. Farm. 36 3-4 (1985): 43-45.
    Published
Thesis / Dissertation
  1. Soveral, Graça. "Comportamento osmótico de vesículas da membrana apical do túbulo proximal do rim de coelho". PhD, Universidade de Lisboa Faculdade de Farmácia, 1995.
  2. Soveral, Graça. "Síntese e utilização de uma galactosilceramida fluorescente para o diagnóstico da doença de Krabbe". Master, Universidade de Lisboa Faculdade de Farmácia, 1987.
  3. Soveral, Graça. "Purificação da ¿-galactosidase – Relatório para uma aula teórico-prática". Master, Universidade de Lisboa Faculdade de Farmácia, 1987.

Intellectual property

Patent
  1. Soveral, Graça; Casini, Angela. 2013. "INHIBITORS OF AQUAGLYCEROPORINS, METHODS AND USES THEREOF, WO 2013/005170".
  2. Soveral, Graça; Casini, Angela. 2012. "INHIBITORS OF AQUAGLYCEROPORINS, METHODS AND USES THEREOF, PCT/IB2012/05341". Portugal.

Other

Other output
  1. Epilogue. in the book "Aquaporins in Health and Disease: New molecular targets for drug discovery". 2016. Angela Casini; Graça Soveral. https://doi.org/10.1201%2Fb19017-20.
    10.1201/b19017-20
  2. FEBS 50th Anniversary Virtual Issue: Portugal. This celebratory Virtual Issue for the 50th anniversary of FEBS (2014) highlights the high quality and diversity of biochemistry research carried out in Portugal. Up to 2013, 303 articles were published in FEBS Letters and The FEBS Journal / European Journal of Biochemistry with at least one author having Portugal as an address.. 2014. Aureliano, M.; Antunes, Fernando; Castanho, Miguel; Marcos, João Carlos; Soveral, Graça. http://hdl.handle.net/10400.1/8342.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/03/17 Aquaporins as emergent drug targets for obesity and cancer Symposium Metals and Beyond
Technical University of Munich TUM, Germany (Munich, Germany)
2023/03/03 Aquaporins as emergent drug targets for obesity and cancer Symposium
Department of Clinical Medicine Aarhus University, Denmark (Aahrus, Denmark)
2022/06/22 Aquaporins as emergent drug targets for obesity and cancer Symposium 6-Membrane Transporters and Channels: Translating Basic Research to Drug Discovery and Preclinical Development. 54th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI)
the European Society for Clinical Investigation (ESCI) (Bari, Italy)
2019/04/11 Biology of membrane Transport FCUL Biochemistry Masterclass Seminars
Universidade de Lisboa Faculdade de Ciências (Lisboa, Portugal)
2018/07/08 Aquaporins as sensors for turgor and cell volume regulation The 43rd FEBS Congress, Prague, Check Republic, July 7-12 2018. The 43rd FEBS Congress
FEBS (Prague, Czech Republic)
2018/04/20 Transporters and channels in cell membranes: promising drug targets for old diseases. XXV Aniversário do Curso de Bioquímica. Campus de Gambelas, Universidade do Algarve, 20 de Abril 2018 XXV Aniversário do Curso de Bioquímica
Universidade do Algarve (Faro, Portugal)
2017/10/25 Aquaporins in human diseases - promising targets for drug development¿ The 1st FEBS3+ Joint Meeting of the French-Portuguese-Spanish Biochemical and Molecular Biology Societies. Barcelona, Spain, October 23-26, 2017 FEBS3+ Joint Meeting of the French-Portuguese-Spanish Biochemical and Molecular Biology Societies
FEBS (Barcelone, Spain)
2017/09/08 Aquaporin channels in obesity and cancer: discovery of new pharmacological blockers” CNC Seminars, Universidade de Coimbra, 8 de Setembro 2017 CNC Seminars
CNC Universidade de Coimbra (Coimbra, Portugal)
2017/07/18 Roles of Aquaporins in health and disease: promising targets for drug discovery¿. 19th International Union for Pure and Applied Biophysics Congress 11th European Biophysics Congress EBSA, Edinburgh, UK, July 16th–20th 2017. 19th International Union for Pure and Applied Biophysics Congress 11th European Biophysics Congress EBSA
EBSA and IUPAB (Edinburgh, United Kingdom)
2017/06/12 Aquaporins are novel targets for obesity and cancer. Translational Research and Innovation in Human and Health Sciences, CiiEM, Monte da Caparica, Portugal, 11-13 Junho 2017. Translational Research and Innovation in Human and Health Sciences
(Caparica, Portugal)
2017/02/03 Aquaporinas na Saúde e na Doença VII Simpósio do núcleo de estudos de doenças raras (NEDR), Sociedade Portuguesa de Medicina Interna Hotel Villa Galé, Coimbra, 3-4 Fevereiro 2017 VII Simpósio do núcleo de estudos de doenças raras (NEDR)
Sociedade Portuguesa de Medicina Interna (Coimbra, Portugal)
2016/05/20 Aquaporins in membranes: novel targets for drug discovery. CNC.IBILI Seminars, Universidade de Coimbra, 20 de Maio 2016. CNC.IBILI Seminars
CNC.IBILI (Coimbra, Portugal)
2016/03/12 Aquaporin therapeutic modulation: emerging targets for drug discovery ECOST-MEETING-BM1406 Ion Channels and Immune Response toward a global understanding of immune cell physiology and for new therapeutic approaches (IONCHAN-IMMUNRESPON) Lisbon, Portugal, 9th - 12th March 2016 ECOST-MEETING-BM1406 Ion Channels and Immune Response toward a global understanding of immune cell physiology and for new therapeutic approaches (IONCHAN-IMMUNRESPON)
(Lisboa, Portugal)
2015/12/14 Aquaporin channels in membranes: novel therapeutic targets for old diseases. iMed Seminars, 14 de Dezembro 2015. iMed Seminars
Universidade de Lisboa Faculdade de Farmácia (Lisboa, Portugal)
2015/08/25 Aquaporin channels in membranes: therapeutic targets for chronic diseases. 44th Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology (SBBq) and 23rd International Congress of International Union for Biochemistry and Molecular Biology, Foz do Iguaçu, Paraná, Brazil, 24-28th August 2015 44th Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology (SBBq) and 23rd International Congress of International Union for Biochemistry and Molecular Biology. SYMPOSIUM PORTUGAL-BRAZIL: BIOMEMBRANES AND TRANSPORTERS: NEW TARGETS FOR OLD DISEASES
SBBq (Foz do Iguaçu, Brazil)
2014/06/11 Aquaporin channels regulation: targeting new players in old diseases. XIVth Congress of the Spanish Biophysical Society, Alcalá de Henares (Madrid), Spain, 11-13 June 2014 XIVth Congress of the Spanish Biophysical Society
(Alcalá de Henares, Spain)
2012/09/09 Novel metal-based scaffolds for aquaporin regulation. Joint FEPS and Spanish Physiological Society Scientific Congress 2012, Santiago de Compostela, 8 - 11 Sept 2012. Joint FEPS and Spanish Physiological Society Scientific Congress 2012
(Santiago de Compostela, Spain)
2012/07/04 Aquaporin gating in cell homeostasis and drug discovery. International Congress of the Spanish Biophysical Society, Barcelone, Spain, 3 - 6 July 2012 International Congress of the Spanish Biophysical Society
(Barcelone, Spain)
2012/01/23 Aquaporin regulation: pH sensing and inhibition by metal compounds. COST Action CM0902 – Molecular machines for ion translocation across biomembranes, 2nd annual meeting, Bari, Italy, 23 Jan 2012. COST Action CM0902 – Molecular machines for ion translocation across biomembranes
(Bari, Italy)
2011/07/10 Aquaporin water channels: function and regulation by membrane stress. 3rd Italian-Hipano-Portuguese Workshop on the Molecular Biology and Biophysics of Ion Channels and Transporters, Imola, Italy, 10th July 2011. 3rd Italian-Hipano-Portuguese Workshop on the Molecular Biology and Biophysics of Ion Channels and Transporters
(Imola, Italy)
2011/05/10 Aquaporin water channels: cell valves for volume regulation. WORKSHOP - Chemical Biology and Bioengineering, Requimte, DQ/FCT-UNL, 10 de Maio 2011 WORKSHOP - Chemical Biology and Bioengineering
DQ/FCT-UNL (Caparica, Portugal)
2010/03/20 Aquaporins regulating cell volume. COST Action CM0902 – Molecular machines for ion translocation across biomembranes, 1st annual meeting, Frankfurt, Germany, 20th March 2010. COST Action CM0902 – Molecular machines for ion translocation across biomembranes, 1st annual meeting
(Frankfurt, Germany)
2010/01/27 Membrane transport and regulation: How aquaporins regulate cell volume. Institute for Research in Biomedicine (IRB) - Seminars, Barcelone, Spain, 27 Jan 2010 Institute for Research in Biomedicine (IRB) - Seminars
(Barcelone, Spain)
2009/10/01 A volume regulatory role of aquaporins triggered by membrane stress. VII Iberoamerican Congress of Biophysics, Búzios, Rio de Janeiro, Brazil, 30 Sept - 3 Oct 2009 VII Iberoamerican Congress of Biophysics
SBBq (Buzios, Brazil)
2009/06/16 Membrane transport and regulation: How aquaporins regulate cell volume. Ciclo de Seminários CBAA, Instituto Superior de Agronomia, 16 de Junho 2009 Ciclo de Seminários CBAA
Instituto Superior de Agronomia (Lisboa, Portugal)
2009/04/24 Looking into Membrane Transport and Regulation: from nanovesicles to tubular organs. Seminários do iMed, FFUL, 24 de Abril 2009 Seminários do iMed
Universidade de Lisboa Faculdade de Farmácia (Lisboa, Portugal)
2008/03 Conceitos teóricos sobre alimentação e puericultura. Workshop “Nutrição e Puericultura” organizado pela Associação de Estudantes da Faculdade de Farmácia de Lisboa, FFUL, Março 2008. Workshop “Nutrição e Puericultura”
AEFFUL (Lisboa, Portugal)
2007/02/03 Aquaporins in Health and Disease: from Structure to Function. Workshop “Proteins in Health and Disease: from Structure to Function”, Faculdade de Farmácia, Universidade de Lisboa, 3 de Fevereiro 2007. Proteins in Health and Disease: from Structure to Function
FFUL (Lisboa, Portugal)
2005/12/14 Nutrição e metabolismo. “Conferências de Bioquímica”, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 14 de Dezembro 2005. Conferências de Bioquímica
Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa (Caparica, Portugal)
2005/10/02 Biological Transport: an overview. 6th Short Course of the Portuguese Biophysical Society – From Membrane Transport to Neurosciences, Santarém, Portugal, Oct 2005 6th Short Course of the Portuguese Biophysical Society – From Membrane Transport to Neurosciences
SPBf (Santarém, Portugal)
2004/12/14 Equilíbrio de Cores e Sabores. “Conferências de Bioquímica”, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 14 de Dezembro 2004. Conferências de Bioquímica
Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa (Caparica, Portugal)
2003/07/01 A soja na alimentação e na prevenção de doenças crónicas. Simpósio “Soja, Alimentação e Saúde”, Faculdade de Farmácia, Universidade de Lisboa, 1 de Julho 2003 Soja, Alimentação e Saúde
FFUL (Lisboa, Portugal)
1999/11/11 Alimentação Equilibrada. Simpósio “Alimentação e Distúrbios Alimentares”, Faculdade de Farmácia, Universidade de Lisboa, 11 de Novembro 1999. Simpósio “Alimentação e Distúrbios Alimentares”
Faculdade de Farmácia, Universidade de Lisboa (Lisboa, Portugal)
1999/01/13 Membranas biológicas - transporte de água em tecidos. “V Ciclo de Conferências do Departamento de Química”, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 13 de Janeiro 1999. V Ciclo de Conferências do Departamento de Química
Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa (Caparica, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024/01/01 - Current Unveiling the impact of aquaporins on immunotherapy efficacy against pancreatic cancer
Supervisor
 Biochemistry (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - Current Involvement of aquaporins in melanoma
Supervisor
 Post-doc
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 - 2022 Discovering new aquaporin Inhibitors with anti-cancer properties
Supervisor
 Bioquímica para a Saúde (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021 - 2022 Aquaporins as drug-targets for pancreatic cancer therapeutics
Supervisor
 Bioquímica para a Saúde (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021 - 2022 Assessment of the expression of AQP3 and AQP7 in human and murine liver and evaluation of the role of AQP7 in hepatocytes
Co-supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 - 2022 Peroxiporins involvement in oxidative stress and their potential for drug targeting
Supervisor
 Biochemistry in Health (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020 - 2021 Aquaporin inhibitors with anticancer properties - computational screening and functional validation
Supervisor
 Bioquímica (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2020 - 2021 Involvement of aquaporin-3 in Melanoma
Co-supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - 2021 Aquaporins involvement in hepatic ischemia-reperfusion injury
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017 - 2021 Aquaporin inhibitors as cancer chemotherapeutic agents using a nanotechnological approach
Co-supervisor
 Pharmacy (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - 2020 Effect of dietary amino acids on glycerol absorption via intestinal aquaporins: a mechanism for fat accumulation?
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - 2020 Aquaporin modulators with anti-cancer properties
Supervisor
 Bioquímica (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2018 - 2019 Involvement of Aquaporins in pancreatic cancer and melanoma: effect of metallodrugs on cell migration
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 - 2019 Screening and Validation of Aquaporin Inhibitors for Cancer Therapeutics
Supervisor
 Bioquímica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015 - 2019 Aquaporins in metabolic syndrome: new targets for drug discovery
Supervisor
 Pharmacy, Biochemistry (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015 - 2019 Membrane permeability and aquaporin involvement in oxidative stress and cancer
Supervisor
 Pharmacy (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017 - 2018 Modulation of aquaporin 7 in adipocytes by miRNAs
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017 - 2018 Evaluation of aquaporins in cancer as potential biomarkers or drug targets
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016 - 2018 Modulation of aquaporins gene expression by n-3 polyunsaturated fatty acids (PUFA) lipid structures in white and brown adipose tissue from hamsters
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016 - 2018 Effect of nutritional supplements on the aquaporin-mediated oxidative stress
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014 - 2018 Targeting human aquaporin function: physiological and chemical approaches
Supervisor
 Farmácia (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2013 - 2018 Characterization of nine Vitis vinifera aquaporins upon heterologous expression in yeast - Transport activity and regulation.
Co-supervisor
 Bolsa de pós-doutoramento financiada pela Fundação para a Ciência e Tecnologia, SFRH/BPD/89427/2012 (Other)
2016 - 2017 Valor nutricional de leguminosas: comparação de sementes in natura, secas e germinadas
Co-supervisor
 Controlo de Qualidade e Toxicologia dos Alimentos (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2013 - 2016 Towards understanding the origin of ammonium sensitivity and an improved tolerance through the study of natural nitrogen isotopic signature: isotopic fractionation during ammonium/ammonia uptake in ammonium-fed plants.
Co-supervisor
 Post-doc Fellow SFRH/BPD/90436/2012 (Other)
2014 - 2015 Expression of Aquaporins in pancreatic tumors: new targets for cancer therapy?
Supervisor
 Biologia Molecular e Genética (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2013 - 2015 Involvement of Aquaporins in Hydrogen Peroxide Permeation
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2013 - 2014 Screening for aquaporin 1 and 3 inhibitors in human red blood cells with stopped-flow light scattering method
Supervisor
 Erasmus Program (Master)
Univerza v Ljubljani, Slovenia
2010 - 2014 Biological membranes – biophysical properties and aquaporin function
Supervisor
 Pharmacy - Biochemistry (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2009 - 2014 Aquaporins in adipocytes: insights into the pathophysiology of human obesity
Supervisor
 Pharmacy - Biochemistry (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2012 - 2013 Efeito de um composto organometálico de Au (III) na actividade sa aquagliceroporina-3
Supervisor
 Bioquímica Estrutural e Funcional (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012 - 2013 Caracterização funcional das aquaporinas - 3 a 7 de mamifero por expressão heteróloga em leveduras
Supervisor
 Bioquímica Estrutural e Funcional (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2012 - 2013 Nanoformulations of a potent aquaporin-3 inhibitor with cytotoxic effect against cancer cell lines
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2011 - 2013 Transporters and Pharmacokinetics
Co-supervisor
 Post-doc training (Other)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2010 - 2012 Assistant Researcher
Co-supervisor
 Supervision of researcher (Other)
REQUIMTE, Portugal
2010 - 2011 Alterações de pH após adição de pulsos de glucose a Saccharomyces cerevisiae: Estimativa de parâmetros a partir da modelação matemática do comportamento cinético-metabólico
Co-supervisor
 Bioquímica Estrutural e Funcional (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2008 - 2011 Predicting Transporter Effects on the Pharmacokinetics of Metabolized Drugs
Co-supervisor
 Pharmacy (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2008 - 2010 Biomolecular characterization of the erythrocyte modifications provoked by Babesia bovis-infection
Co-supervisor
 Biochemistry (PhD)
Universidade Nova de Lisboa, Portugal
2008 - 2009 Permeabilidade do tecido adiposo à água e ao glicerol: efeito da suplementação alimentar em isómeros do ácido linoleico conjugado (CLA)
Supervisor
 Biotecnologia (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2006 - 2008 Transporte mediado de água em leveduras – aspectos com relevância industrial
Co-supervisor
 Tecnologia Alimentar/Qualidade (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2003 - 2005 Do Leite Materno às bebidas de maior consumo em Portugal – sua contribuição para a exposição humana a elementos minerais essenciais e tóxicos
Supervisor
 Controlo de Qualidade e Segurança Alimentar (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
1996 - 2000 Transporte de água e electrólitos em membranas de epitélios
Co-supervisor
 Biochemistry (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2022 - 2022 The Biochemistry Global Summit - 25th IUBMB Congress, 46th FEBS Congress and 15th PABMB Congress, 9 to 14 July 2022. https://2022congress.febs-iubmb-pabmb.org (2022/07/09 - 2022/07/14)
2019 - 2019 7th SFICT Workshop, Siestre Levante, Genova, Italy (2019/10/02 - 2019/10/05)
Conference (Member of the Organising Committee)
 Sociedade Portuguesa de Biofísica, Portugal
2018 - 2018 Congresso Nacional de Bioquímica (CNB) and World Meeting of the International Society for Free Radical Research (SFRRI). Lisbon, Portugal. (2018/06/04 - 2018/06/07)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Bioquímica, Portugal
2018 - 2018 XX Congress of the Portuguese Biochemical Society, Lisbon, Portugal. (2018/06/04 - 2018/06/07)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Bioquímica, Portugal
2017 - 2017 28th Ion Channel Meeting, 6th SFICT Workshop, Sète, Montpellier, France. (2017/09/13 - 2017/09/17)
Conference (Member of the Organising Committee)
 Sociedade Portuguesa de Biofísica, Portugal
2017 - 2017 FEBS3+, The 1st Meeting of the French-Portuguese-Spanish Biochemical Societies. Barcelona, Spain. (2017/10/23 - 2017/10/26)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Bioquímica, Portugal
2016 - 2016 5th International Iberian Biophysics Congress, Porto, Portugal. (2016/06/14 - 2016/06/17)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Biofísica, Portugal
2016 - 2016 COST Action BM1406 MC/WG Meeting, Ion Channels and Immune Response toward a global understanding of immune cell physiology and for new therapeutic approaches (IONCHAN-IMMUNRESPON). Faculdade de Farmácia, Universidade de Lisboa, Portugal. (2016/03/09 - 2016/03/11)
Conference (Co-organisor)
 European Cooperation in Science and Technology, Belgium
2016 - 2016 XIX Congress of the Portuguese Biochemical Society, Guimarães, Portugal. (2016/12/08 - 2016/12/10)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Bioquímica, Portugal
2015 - 2015 5th Workshop – Structure and function of ion channels and transporters. Lisboa, Portugal. (2015/11/12 - 2015/11/14)
Conference (President of the Organising Committee)
 Sociedade Portuguesa de Biofísica, Portugal
2015 - 2015 COST Action CM1106 Training School, Chemical Approaches to Targeting Drug Resistance in Cancer Stem Cells. Faculdade de Farmácia, Universidade de Lisboa, Portugal. (2015/11/23 - 2015/11/25)
Conference (Co-organisor)
 European Cooperation in Science and Technology, Belgium
2014 - 2014 XVIII Congress of the Portuguese Biochemical Society, Porto, Portugal. (2014/12/07 - 2014/12/10)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Bioquímica, Portugal
2013 - 2013 4th Italian-Hispano-Portuguese Workshop – Molecular Biology and Biophysics of Ion Channels and Transporters, Mallorca, Spain. (2013/10/17 - 2013/10/19)
Conference (Member of the Organising Committee)
 Sociedade Portuguesa de Biofísica, Portugal
2013 - 2013 9th European Biophysics Congress EBSA 2013, Lisboa, Portugal. (2013/07/13 - 2013/07/17)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Biofísica, Portugal
2013 - 2013 COST Action CM0902 Training School, Molecular Machineries in Membranes. Faculdade de Farmácia, Universidade de Lisboa, Portugal. (2013/05/15 - 2013/05/18)
Conference (Co-organisor)
 European Cooperation in Science and Technology, Belgium
2012 - 2012 Pharmacokinetics and the Pharmaceutical Sciences – A tribute to the career of Professor José Morais. Faculdade de Farmácia de Lisboa, Portugal. (2012/06/22 - 2012/06/22)
Conference (Co-organisor)
 Universidade de Lisboa Faculdade de Farmácia, Portugal
2012 - 2012 22nd IUBMB and 37th FEBS Congress – From single molecules to systems biology, Seville, Spain. Co-Organization SPB- SEBBM. (2012/09/04 - 2012/09/08)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Bioquímica, Portugal
2011 - 2011 10th Short Course of the Portuguese Biophysical Society – Nanosciences for Life, Santarém, Portugal. (2011/11/17 - 2011/11/19)
Conference (Co-organisor)
 Sociedade Portuguesa de Biofísica, Portugal
2010 - 2010 9th Short Course of the Portuguese Biophysical Society – Protein folding, misfolding and disease, Santarém, Portugal. (2010/10/30 - 2010/11/01)
Conference (Member of the Organising Committee)
 Sociedade Portuguesa de Biofísica, Portugal
2009 - 2009 8th Short Course of the Portuguese Biophysical Society – Systems Biology, Santarém, Portugal. (2009/10/30 - 2009/11/01)
Conference (Member of the Organising Committee)
 Sociedade Portuguesa de Biofísica, Portugal
2008 - 2008 1st Portuguese-Spanish-British Joint Biophysics Congress, Lisboa, Portugal. (2008/07/10 - 2008/07/13)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Biofísica, Portugal
2007 - 2007 7th Short Course of the Portuguese Biophysical Society – Biospectroscopy and Imaging, Santarém, Portugal. Outubro de 2007. (2007/10/01 - 2007/10/04)
Conference (Member of the Organising Committee)
 Sociedade Portuguesa de Biofísica, Portugal
2007 - 2007 Workshop “Proteins in Health and Disease: from Structure to Function”, Faculdade de Farmácia de Lisboa, Portugal. (2007/02/02 - 2007/02/03)
Conference (Co-organisor)
 Universidade de Lisboa Faculdade de Farmácia, Portugal
2005 - 2005 6th Short Course of the Portuguese Biophysical Society – From Membrane Transport to Neurosciences, Santarém, Portugal. (2005/10/02 - 2005/10/05)
Conference (Co-organisor)
 Sociedade Portuguesa de Biofísica, Portugal
2005 - 2005 Workshop “Aquaporinas: Relevância no transporte de água”, Instituto Superior de Agronomia, Universidade Técnica de Lisboa, Portugal. (2005/05/08 - 2005/05/08)
Conference (Co-organisor)
 Universidade de Lisboa Instituto Superior de Agronomia, Portugal
2004 - 2004 3rd Portuguese-Spanish Biophysics Congress, Lisboa, Portugal. (2004/10/29 - 2004/11/01)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Biofísica, Portugal
2003 - 2003 Simpósio – “Soja, Alimentação e Saúde”, Faculdade de Farmácia de Lisboa, Portugal. (2003/06/22 - 2003/06/22)
Conference (Co-organisor)
 Universidade de Lisboa Faculdade de Farmácia, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023 Novel functions of aquaporin water channels in breast cancer: regulators of cellular polarity and response to anticancer therapies
(Thesis) Main arguer
 Sarannya Edamana (PhD)
Aarhus Universitet Faculty of Health, Denmark
2022 The role of nutrient transport by cancer cells in the interaction between type 2 Diabetes Mellitus and breast cancer
(Thesis) Main arguer
 Cláudia Raquel Santos Silva (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2021 The effect of cholesterol on the function of eukaryotic membrane transporters for amino acids
(Thesis) Main arguer
 Jessica Cosco (PhD)
Università della Calabria Dipartimento di Biologia Ecologia e Scienze della Terra, Italy
2021 Regulation of the KtrAB cation channel
(Thesis) Main arguer
 Celso Moura Teixeira Duarte (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 Targeting the G Protein coupled receptors CaSR and V2R in renal pathophysiology
(Thesis) Main arguer
 Maria Venneri (PhD)
Università degli Studi di Bari Aldo Moro, Italy
2021 Targeting the carotid bodies to treat obesity
(Thesis) Main arguer
 Bernardete Sofia Freitas de Melo (PhD)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019 Disentangling the function and structural modularity of the membrane arm from respiratory complex I
(Thesis) Main arguer
 Paulo Jorge Gomes de Castro (PhD)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019 Insights into fluoroquinolones uptake: a biophysical and biochemical approach Insights into fluoroquinolones uptake: a biophysical and biochemical approach.
Thesis Member
 Mariana Santos Ferreira de Sá (PhD)
Universidade do Porto Faculdade de Ciências, Portugal
2019 Synaptic zinc changes in hippocampal CA3 area
(Thesis) Main arguer
 Fátima Maria Castelo Bastos da Silva Neves (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019 Hormonal control of membrane transporters in male reproductive tract
(Thesis) Main arguer
 Raquel Alexandra Lages Bernardino (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 Recombinant production and purification of ion channels for biomimetic membranes and cryo-EM studies
(Thesis) Main arguer
 Sarah Spruce Preisler (PhD)
Københavns Universitet, Denmark
2018 Anoctamin I - A member of a novel family of ion channels with extended functions and significance in disease
(Thesis) Main arguer
 Joana Ramos Rapaz Lérias (PhD)
Universidade de Lisboa Faculdade de Ciências, Portugal
2017 Aquaporin in Cancer Cell Migration: Discovery of New Pharmacological Blockers and a Novel Lithium Sensor
(Thesis) Main arguer
 Jinxin Pei (PhD)
The University of Adelaide Adelaide Medical School, Australia
2016 The role of nitrite-derived nitric oxide in gastric physiology: biochemical mechanisms, molecular targets and the modulatory effect of red wine
(Thesis) Main arguer
 Cassilda Maria Lopes Pereira (PhD)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2015 Efeito de diferentes métodos de confeção no valor nutricional da carne de bovino – estudo experimental nas carnes Barrosã e Mertolenga
(Thesis) Main arguer
 Anabela Ferreira Lopes (PhD)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2015 Study of grapevine solute transporters involved in berry quality. A biochemical and molecular approach
(Thesis) Main arguer
 Henrique Luís Silva de Noronha (PhD)
Universidade do Minho Escola de Ciências, Portugal
2014 Biological Membranes – biophysical properties and aquaporin function
Supervisor
 Ana Paula Cavaco da Silva Martins (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014 Segurança e biodisponibilidade de suplementos alimentares
(Thesis) Main arguer
 Ivone Mariana da Costa Almeida (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 Estudio sobre el papel de las acuaporinas en procesos de proliferación celular
(Thesis) Main arguer
 Ana Galan Cobo (PhD)
Universidad de Sevilla, Spain

Instituto de Biomedicina de Sevilla, Spain
2014 Aquaporins in adipocytes: insights into the pathophysiology of human obesity
Supervisor
 Ana Paula da Silva Madeira (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2013 Impact of Gestational Diabetes Mellitus in the maternal-to-fetal transport of nutrients and on placental development
(Thesis) Main arguer
 João Ricardo Diniz de Araújo (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2013 Estudo, caracterização e desenvolvimento de sistemas de libertação controlada para as quinolonas e seus derivados
(Thesis) Main arguer
 Isabel Cristina de Sá Correia de Sousa (PhD)
Universidade do Porto Faculdade de Ciências, Portugal
2012 Re and 99mTc organometallic complexes for targeting nitric oxide synthase
Thesis Member
 Bruno Luís Jesus Pinto de Oliveira (PhD)
Universidade de Lisboa Faculdade de Ciências, Portugal
2010 Avaliação de vitaminas lipossolúveis e seus precursores em leite – aplicação ao leite de Minhota, raça autóctone portuguesa declarada em vias de extinção em 2002
(Thesis) Main arguer
 Heryka Myrna Maia Ramalho (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2010 Regulación por hipoxia del gen de AQP1. Estudios moleculares y funcionales
(Thesis) Main arguer
 Irene Abreu Rodriguez (PhD)
Universidad de Sevilla, Spain
2010 Energy transduction by respiratory complex I
Thesis Member
 Ana Paula Gonçalves Batista (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2009 Análise molecular de lectinas em sementes de leguminosas
Thesis Member
 Ana Cristina Ferreira da Conceição Ribeiro (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2001 Transporte de água e electrólitos em membranas de epitélios
Thesis Member
 Paula de Fátima Domingos Alves (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Association member

Society Organization name Role
2019 - Current Sociedade Portuguesa de Bioquímica (SPB) Portuguese Biochemical Society President
2018 - Current Federation of European Biochemical Societies (FEBS) Member of Council
2015 - Current Portuguese Biophysical Society (SPBf) Treasurer
2015 - 2018 Sociedade Portuguesa de Bioquímica Vice-President
2012 - 2014 Portuguese Biochemical Society General Secretary

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019 - Current Bioquimica Clínica Ciências da Nutrição (Licenciatura) Universidade de Lisboa Faculdade de Medicina, Portugal
2011 - Current Membrane Transport Ciências Biofarmacêuticas (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2008 - Current Bioquímica Clínica Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2007 - Current Nutracêuticos Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2006 - Current Nutrição e Dietética Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2009 - 2013 Elementos de Fisiologia, Nutrição e Dietética Ciências Gastronómicas (Mestrado) Universidade de Lisboa Instituto Superior de Agronomia, Portugal
2006 - 2008 Bioquímica dos Alimentos Dietética e Nutrição (Licenciatura) Universidade de Lisboa Faculdade de Medicina, Portugal
1983 - 2007 Bioquímica I Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2019 - Current FEBS Fellowships Committee
Evaluator
 Federation of European Biochemical Societies, United Kingdom Federation of European Biochemical Societies
2023 - 2023 FCT - Evaluation of PhD fellowships, Coordinator panel Non-academic fellowships Coordenadora do painel Painel de Avaliação Candidaturas em Ambiente Não Académico (CNA) 2023
Coordinator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2016 - 2023 H2020-MSCA-IF-2016 (Expert / Rapporteur) H2020-MSCA-IF-2018 (Expert / Rapporteur) H2020-MSCA-IF-2019 (Expert / Rapporteur) / H2020-MSCA-IF-2023 (Expert / Rapporteur)
Evaluator
 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions, Belgium Horizon 2020
2021 - 2022 Vice-Chair for the 2021 Call for Marie Sklodowska-Curie Postdoctoral Fellowships (HE-MSCA-PF-2021)
Coordinator
 Horizon 2020, Belgium
2021 - 2021 Evaluator and Deputy Chair of the Research and Professional Activities of the Institutes of the Czech Academy of Sciences (CAS) for 2015–2020 (panel member, phase 1 and Deputy Chair, phase 2).
Evaluator
2019 - 2021 FCT - Evaluation of PhD and Post-doc fellowships, Coordinator panel Experimental Biology and Biochemistry (avaliação de bolsas de doutoramento e pós-doutoramento, Coordenadora do painel Biologia Experimental e Bioquímica)
Coordinator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2020 - 2020 Project evaluator, Università degli Studi della Campania Luigi Vanvitelli, Italian Ministry of Education, Italian Scientific Evaluation
Evaluator
 Università degli Studi della Campania Luigi Vanvitelli, Italy Università degli Studi della Campania Luigi Vanvitelli
2018 - 2018 Project evaluator, Italian Ministry of Education, Universities and Research (MIUR)
Evaluator
 Ministero dell'Istruzione dell'Università e della Ricerca, Italy Ministero dell'Istruzione dell'Università e della Ricerca
2016 - 2018 Avaliação de Bolsas de Doutoramento da Universidade de Lisboa
Evaluator
 Universidade de Lisboa Faculdade de Farmácia, Portugal Universidade de Lisboa (ULisboa)
2014 - 2018 Avaliação de candidaturas Programa Doutoral i3DU
Evaluator
 Universidade de Lisboa Faculdade de Farmácia, Portugal Fundação para a Ciência e a Tecnologia
2016 - 2017 FCT avaliação de bolsas de doutoramento e pós-doutoramento (painel Biologia Experimental e Bioquímica)
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal
2013 - 2017 Avaliação de candidaturas Programa Doutoral M2B-PhD
Evaluator
 Universidade de Lisboa Faculdade de Medicina, Portugal Fundação para a Ciência e a Tecnologia
2016 - 2016 Swedish Research Council, Research Environment Grants 2016, external evaluator
Evaluator
 Vetenskapsradet, Sweden Vetenskapsradet
2016 - 2016 European Research Council: ERC Starting, Consolidator and Advanced Grant Calls
Evaluator
 European Research Council, Belgium Horizon 2020
2015 - 2015 Evaluation of the Research and Professional Activities of the Institutes of the Czech Academy of Sciences (CAS) for 2010–2014 (panel member, phase 1 and phase 2)
Evaluator
 Akademie ved Ceske republiky, Czech Republic Akademie ved Ceske republiky
2015 - 2015 Czech Health Research Council, Ministry of Health of the Czech Republic
Evaluator
 Akademie ved Ceske republiky, Czech Republic Akademie ved Ceske republiky
2015 - 2015 External Expert Remote Evaluation COST, Open Call OC-2015-1, Independent External Expert
Evaluator
 European Cooperation in Science and Technology, Belgium European Cooperation in Science and Technology
2014 - 2015 H2020, Avaliador no Programa Europeu Career Development Award (CDA), Human Frontier Science Program (HFSP) Human Frontier Science Program, France Horizon 2020
2012 - 2013 Avaliador de projeto de cooperação transnacional (ações integradas FCT-CAPES; FCT- Índia) (2012 e 2013)
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
Distinctions

Other distinction

2021 Women in Science
Federation of European Biochemical Societies, United Kingdom