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Sara R. D. Gamelas is currently a post-doc fellow at Instituto Superior Técnico (IST). She obtained her PhD in Chemistry in 2024 at the University of Aveiro (UA), her Master's degree in chemistry in 2016, and her bachelor's in Biochemistry in 2014 from the same university. Her interest in Organic Chemistry, combined with the biomedical field, was acquired during her bachelor's degree in Biochemistry at the University of Aveiro (Aveiro, Portugal), where she developed her final project regarding immobilized N-confused porphyrins to use as photosensitizers in the photodynamic inactivation (PDI) of microorganisms. During her Master's thesis in Chemistry (2016), she did an Erasmus internship in Belgium to investigate the ability of photoactive molecules (tetracationic porphyrins), which she synthesized in Aveiro, to be used as photosensitizers for the Photodynamic Therapy of cancer. During that internship, she acquired experience in cell culture, immuno-detection techniques, photodynamic therapy (PDT) in cancer cells, RT-PCR, and PAGE detection. In 2017-2018, Sara was a research fellow at QOPNA and LAQV-REQUIMTE (UA), holding a research BI grant from the FCT project PTDC/QEQ-SUP/5355/2014 under the guidance of PI Doctor Leandro M. O. Lourenço, working on "supramolecular functionalization of carbon nanostructures with porphyrin and phthalocyanine derivatives for sustainable photoinduced energy- and electronic-transfer materials." In 2018-2019, Sara was a research fellow at the same institution, holding a research BI grant from the FCT project PTDC/QUI-QOR/31770/2017 under the guidance of PI Doctor Leandro M. O. Lourenço, working on "imidazole pyrene porphyrin- and phthalocyanine-carbon nanostructure materials assembled through supramolecular interactions for energy- and electronic-transference in photovoltaic solar cells integrated in smart devices." In 2019, Sara was awarded by FCT with her PhD scholarship (SFRH/BD/143549/2019) to work on synthesizing Phthalocyanines and porphyrins for energy transfer processes and biomedical applications. In 2023, Sara was awarded a Fulbright and a FLAD scholarship to work in Dr. Pereira's lab at Washington University School of Medicine in the United States. She developed part of her PhD thesis using click chemistry to prepare porphyrin–antibody bioconjugates in vivo and in vitro for dual imaging modality (PET and optical imaging). She acquired experience in cell culture, mice work, modification of antibodies, and preparation of bioconjugates. Her publication output includes 15 peer-reviewed articles (10 in the Q1, 5 in Q2 and 13 as the first author), 19 oral (12 as presenter), and 17 poster communications (8 as presenter) at conferences. Sara was a participant/organizer of 6 dissemination activities to the public. She was also responsible for tutoring/mentoring 3 BSc students (2019, 2021 and 2024) at LAQV-UA. The students focused on developing novel phthalocyanines or porphyrin to be used as photosensitizers for the PDI of microorganisms of bacteria in their planktonic or biofilm form. Sara was involved in the peer-review of 3 research articles in 2023 and 2024. Also, the editors of Molecules awarded her article "N-Confused porphyrin immobilized on solid supports: Synthesis and metal ions sensing efficacy" to appear as a magazine cover (volume 23, issue 4) in 2018. Currently, her main scientific research interests include (1) synthesis and characterization of porphyrins and phthalocyanines for theranostic applications; (2) click chemistry with tetrazines and TCO; (3) Labeling and antibody conjugation (DFO, TCO, and ALEXA); (4) Photodynamic therapy of cancer cells and microorganisms; (5) Immunofluorescence assays using fluorescently conjugated antibodies.
Identification

Personal identification

Full name
Sara Gamelas

Citation names

  • Gamelas, S. R. D.
  • Gamelas, Sara R. D.
  • S. R. D. Gamelas

Author identifiers

Ciência ID
1F1E-506C-4B47
ORCID iD
0000-0003-4688-8570

Email addresses

  • sara.gamelas@tecnico.ulisboa.pt (Professional)

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Microbiology
  • Exact Sciences - Chemical Sciences - Nuclear Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Portuguese (Mother tongue)
Education
Degree Classification
2019/11/01 - 2024/07/15
Concluded
Chemistry (Doctoral Degree, PhD) (Doutoramento)
LAQV-REQUIMTE Aveiro, Portugal

Universidade de Aveiro Departamento de Química, Portugal
"Synthesis of phthalocyanines and porphyrins for energy transfer systems and biomedical applications" (THESIS/DISSERTATION)
Approved
2023/02/10 - 2023/02/10
Concluded
Basic Knowledge of Radiation Safety for Handling Positron-emitting Radioactive Material - Cert. Nº PET-1405 (Outros)
Washington University in St Louis School of Medicine Mallinckrodt Institute of Radiology, United States
Approved
2023/02/10 - 2023/02/10
Concluded
Basic Knowledge of Radiation Safety for Handling Radioactive Material (Cert. Nº RSE-16452) (Outros)
Washington University in St Louis School of Medicine Mallinckrodt Institute of Radiology, United States
Approved
2023/02 - 2023/02
Concluded
Animal Biohazard Safety, Introduction to Animal Care and Use, Mice and Rats, Rodent Anesthesia and Surgery, Rodent Barrier Orientation (Outros)
Division of Comparative Medicine at Washington University in St Louis School of Medicine, United States
Approved
2023/02 - 2023/02
Concluded
Initial Lab Safety Training (Outros)
Environmental Health and Safety at Washington University in St Louis School of Medicine, United States
Approved
2023/02 - 2023/02
Concluded
Medical Surveillance Questionnaire for Personnel with Animal Contact (Outros)
Occupational Health Services at Washington University in St Louis School of Medicine, United States
Approved
2014/09/01 - 2016/11/30
Concluded
Chemistry (Master's Degree, MsC) (Mestrado)
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal

Universidade de Aveiro Departamento de Química, Portugal
"Porphyrin derivatives and mRNA alternative splicing induced by photodynamic therapy" (THESIS/DISSERTATION)
16
2011 - 2014
Concluded
Biochemistry (Bachelor's degree, BsC) (Licenciatura)
Universidade de Aveiro Departamento de Química, Portugal
"New immobilized N-confused porphyrins: Synthesis and biological evaluation" (THESIS/DISSERTATION)
14
Affiliation

Science

Category
Host institution
Employer
2024/11/01 - Current Postdoc (Research) Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
Universidade de Lisboa Centro de Química Estrutural, Portugal
2023/02 - 2023/08 Visiting Researcher (Research) Fundação Luso-Americana para o Desenvolvimento, Portugal
Washington University in St Louis School of Medicine Mallinckrodt Institute of Radiology, United States
2023/02 - 2023/08 Visiting Researcher (Research) Fulbright Portugal and Fundação para a Ciência e Tecnologia, Portugal
Washington University in St Louis School of Medicine Mallinckrodt Institute of Radiology, United States
2016/02/01 - 2016/06/30 Research Trainee (Research) Erasmus Plus, Belgium
GIGA Institute, Université de Liège, Belgium

Teaching in Higher Education

Category
Host institution
Employer
2025/02 - Current Invited Assistant Professor (University Teacher) Universidade de Lisboa Instituto Superior Técnico, Portugal

Others

Category
Host institution
Employer
2019/11/01 - 2024/07/15 PhD Research Fellow Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Aveiro Departamento de Química, Portugal
2018/11/01 - 2019/10/31 Research Fellow (FCT project PTDC/QUI-QOR/31770/2017) Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal
2017/11/01 - 2018/10/31 Research Fellow (FCT project PTDC/QEQ-SUP/5355/2014) Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal
2017/09/01 - 2017/10/31 Volunteer in Analytical Chemistry Lab (N-Confused Porphyrin Immobilized on Solid Supports: Synthesis and Metal Ions Sensing Efficacy) Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2017/01/01 - 2017/10/31 Operadora Ajudante 1º Ano Continente Sonae, Portugal
Continente Sonae, Portugal
2013/07/07 - 2013/12/31 Caixeiro Ajudante 1º Ano Tempo Team, Recursos Humanos, Emp. de trabalho temporário, Portugal
SuperPlus- Gestão e Exploração de Areas Comerciais LDA, Portugal
2012/07 - 2012/08 Caixeiro Ajudante 1º Ano Adecco Portugal, Portugal
Marabuto, Produtos Alimentares SA, Portugal
Projects

Grant

Designation Funders
2019/11/01 - 2023/12/31 Synthesis of Phthalocyanines and Porphyrins for Energy Transfer Systems and Biomedical Applications
SFRH/BD/143549/2019
PhD Student Fellow
Universidade de Aveiro Departamento de Química, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2023/02/01 - 2023/08/31 Advances of PET/CT Imaging with a Radio-labeling Photosensitizers for Orthotopic Cancer Target
Visiting Researcher
Washington University in St Louis School of Medicine Mallinckrodt Institute of Radiology, United States
Fulbright Portugal

Fundação para a Ciência e a Tecnologia
Concluded
2023/02/01 - 2023/08/31 Advances of PET/CT Imaging with a Radio-labeling Photosensitizers for Orthotopic Cancer Target
Visiting Researcher
Washington University in St Louis School of Medicine Mallinckrodt Institute of Radiology, United States
Fundação Luso-Americana para o Desenvolvimento
Concluded
2018/11/01 - 2019/10/31 Imidazole Pyrene Porphyrin- and Phthalocyanine-Carbon Nanostructure Materials Assembled through Supramolecular Interactions for Energy- and Electronic-transference in Photovoltaic Solar Cells Integrated in Smart Devices
PTDC/QUI-QOR/31770/2017
Research Fellow
Universidade de Aveiro Departamento de Química, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2017/11/01 - 2018/10/31 Supramolecular Functionalization of Carbon Nanostructures with Porphyrin and Phthalocyanine Derivatives for Sustainable Photoinduced Energy- and Electronic-transfer Materials
PTDC/QEQ-SUP/5355/2014
Research Fellow
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal

LAQV-REQUIMTE Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/01 - 2016/06 Alternative Splicing of mRNA Induced by Photodynamic Therapy Using Tetracationic Porphyrins
Erasmus Internship Scholarship
Scientific Initiation Fellow
GIGA Institute, Université de Liège, Belgium
Erasmus Plus
Concluded

Other

Designation Funders
2018/07 - 2021/12 Imidazole Pyrene Porphyrin- and Phthalocyanine-Carbon Nanostructure Materials Assembled through Supramolecular Interactions for Energy- and Electronic-transference in Photovoltaic Solar Cells Integrated in Smart Devices
PTDC/QUI-QOR/31770/2017
Participant member
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal

LAQV-REQUIMTE Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2017/11 - 2019/12 Supramolecular Functionalization of Carbon Nanostructures with Porphyrin and Phthalocyanine Derivatives for Sustainable Photoinduced Energy­- and Electronic­-transfer Materials
PTDC/QEQ-SUP/5355/2014
Participant member
Universidade de Aveiro Departamento de Química, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference poster
  1. de Sousa, Beatriz P.; Ana R. Monteiro; Gamelas, S. R. D.; Fateixa, Sara; C. I. V. Ramos; M. G. P. M. S. Neves; Lourenço, L. M. O.; Trindade, Tito. Corresponding author: de Sousa, Beatriz P.. "Bioprobes based on 2D materials interfaces functionalized with fluorescent macrocycles". Paper presented in Jornadas do CICECO 2024, Oliveira de Azeméis (Portugal) 10th of October 2024, 2024.
  2. Gamelas, Sara R. D.; Bartolomeu, Maria; Vieira, Cátia; Faustino, Maria; TOME JOAO P C OR TOME JPC OR TOME J P C ; Tomé, Augusto C.; Almeida, Adelaide; Leandro M. O. Lourenço. Corresponding author: Almeida, Adelaide. "Boosting Bacterial Photodynamic Inactivation via the Synergistic Effect of Potassium Iodide and Cationic Zinc(II) Phthalocyanines (P56, pg. 171)". Paper presented in 29th Congress of the International Society of Heterocyclic Chemistry (ISHC 2024), Aveiro, Portugal, 2024.
  3. Cláudia P. S. Ribeiro; Gamelas, S. R. D.; Leandro M. O. Lourenço; TOME JOAO P C OR TOME JPC OR TOME J P C ; Pereira, Patrícia. Corresponding author: Cláudia P. S. Ribeiro. "Pre-targeting Bioorthogonal Strategy for Tethering Photoactive BODIPY onto the Plasma Membrane of HER2+ Gastric Tumours". Paper presented in 6th edition of CQE Days, Academia de Ciências de Lisboa, Portugal, 2024.
  4. Gamelas, Sara R. D.; Shayla Shmuel; Na-Keysha Berry; TOME JOAO P C OR TOME JPC OR TOME J P C ; Tomé, Augusto C.; Leandro M. O. Lourenço; Patricia M. R. Pereira. Corresponding author: Gamelas, Sara R. D.. "In Vivo Dual Antibody-PET and Optical Imaging through Biorthogonal Diels-Alder Click Chemistry (IGT-35)". Paper presented in 19th European Molecular Imaging Meeting (19th EMIM), Porto, Portugal, 2024.
  5. Cláudia P. S. Ribeiro; Gamelas, S. R. D.; Patricia M. R. Pereira; Leandro M. O. Lourenço; TOME JOAO P C OR TOME JPC OR TOME J P C . Corresponding author: Cláudia P. S. Ribeiro. "The Synthesis of a BODIPY-Tetrazine and Its Potential Application in Gastric Cancer Cells via Click Chemistry (P69, pg. 166)". Paper presented in 15th National Organic Chemistry Meeting (15ENQO) and the 8th National Medicinal Chemistry Meeting (8ENQT), Faro, Portugal, 2024.
  6. Vieira, Cátia; Bartolomeu, Maria; Pedro, Sónia N.; Ana T.P.C. Gomes; Dias, Cristina J.; Gamelas, Sara R. D.; Leandro M. O. Lourenço; et al. Corresponding author: Almeida, Adelaide. "Investigation of the Potential of Deep Eutectic Solvents (DES) as Alternative Solvents in Antimicrobial Photodynamic Therapy (P2, pg. 312)". Paper presented in 20th Congress of the European Society for Photobiology (ESP2023), Lyon, France, 2023.
  7. Gamelas, Sara R. D.; TOME JOAO P C OR TOME JPC OR TOME J P C ; Tomé, Augusto C.; Leandro M. O. Lourenço; Pereira, Patrícia. Corresponding author: Gamelas, Sara R. D.. "Using Click Chemistry to Deliver New Photosensitizers to Gastric Tumors". Paper presented in Oncologic Imaging Program Poster Session,Washington University School of Medicine at Washington University Medical Center, Saint Louis, MO, USA, 2023.
  8. Gamelas, Sara R. D.; TOME JOAO P C OR TOME JPC OR TOME J P C ; Tomé, Augusto C.; Leandro M. O. Lourenço; Pereira, Patrícia. Corresponding author: Gamelas, Sara R. D.. "Biorthogonal Pretargeting for Anchoring Photoactive Porphyrins on the Plasma Membrane of HER2+ Gastric Tumors". Paper presented in MIR symposium, Department of Radiology, Washington University School of Medicine, St Louis, MO, USA, 2023.
  9. Gamelas, Sara R. D.; Vieira, Cátia; Maria Bartolomeu; M. Amparo F. Faustino; TOME JOAO P C OR TOME JPC OR TOME J P C ; Tomé, Augusto C.; Almeida, Adelaide; Leandro M. O. Lourenço. Corresponding author: TOME JOAO P C OR TOME JPC OR TOME J P C. "Antimicrobial Photodynamic Therapy of Gram-negative and Gram-positive Bacteria through the Action of Cationic Si(IV) Phthalocyanines (pg. 467)". Paper presented in 12th International Conference on Porphyrins and Phthalocyanines (ICPP), Madrid, Spain, 2022.
  10. Gamelas, S. R. D.; Santos, Isabela; Vieira, Cátia; Faustino, Maria; TOME JOAO P C OR TOME JPC OR TOME J P C ; Almeida, Adelaide; Ana T.P.C. Gomes; Lourenço, Leandro. Corresponding author: Gamelas, S. R. D.. "Photoinactivation of Planktonic and Biofilm Forms of Escherichia coli through the Action of Pyrazole-Pyridinium Porphyrinoids (SG|PSG 15, pg. 156))". Paper presented in 4th International Caparica Christmas Conference on Translational Chemistry (IC3CT) 2021, Costa da Caparica, Portugal, 2021.
  11. Gamelas, S. R. D.; Calmeiro, J. M. D; Ana T.P.C. Gomes; Maria Amparo F Faustino; M.G.P.M.S Neves; Almeida, Adelaide; TOME JOAO P C OR TOME JPC OR TOME J P C ; Tomé, Augusto C.; Leandro M. O. Lourenço. Corresponding author: Leandro M. O. Lourenço. "Antimicrobial Photodynamic Therapy of Bioluminescent E. coli Bacteria Using Cationic Porphyrins (pg. 145)". Paper presented in 11th International Conference on Porphyrins and Phthalocyanines (ICPP), Virtual Meeting, 2021.
  12. Cláudia P. S. Ribeiro; Gamelas, S. R. D.; Ana T.P.C. Gomes; Maria Amparo F Faustino; Almeida, Adelaide; TOME JOAO P C OR TOME JPC OR TOME J P C ; Leandro M. O. Lourenço. Corresponding author: Leandro M. O. Lourenço. "Unsymmetrical Cationic Porphyrin-Cyclodextrin Dyes for Photoinactivation of Escherichia coli (pg. 414)". Paper presented in 11th International Conference on Porphyrins and Phthalocyanines (ICPP), Virtual Meeting, 2021.
  13. Gamelas, S. R. D.; Santos, Isabela; Vieira, Cátia; Maria Amparo F Faustino; TOME JOAO P C OR TOME JPC OR TOME J P C ; Almeida, Adelaide; Ana T.P.C. Gomes; Lourenço, Leandro. Corresponding author: Gamelas, S. R. D.. "Pyrazole-Pyridinium Porphyrinoids as Powerful Photosensitizers for Photoinactivation of Planktonic and Biofilm Forms of Escherichia coli (PC 119, pg. 208)". Paper presented in 7th Portuguese Young Chemists meeting (PYChem), Virtual Meeting, 2021.
  14. Cláudia P. S. Ribeiro; Gamelas, S. R. D.; Ana T.P.C. Gomes; Maria Amparo F Faustino; Almeida, Adelaide; TOME JOAO P C OR TOME JPC OR TOME J P C ; Leandro M. O. Lourenço. Corresponding author: Cláudia P. S. Ribeiro. "Water Soluble Porphyrin-Cyclodextrin Dyes for Photoinactivation of Escherichia coli (PC119, pg. 200)". Paper presented in 7th Portuguese Young Chemists meeting (PYChem)- Virtual Meeting, 2021.
  15. Gamelas, S. R. D.; Santos, Isabela; Vieira, Cátia; Maria Amparo F Faustino; TOME JOAO P C OR TOME JPC OR TOME J P C ; Almeida, Adelaide; Ana T.P.C. Gomes; Leandro M. O. Lourenço. Corresponding author: Gamelas, S. R. D.. "Porphyrinoids Bearing Pyrazole-Pyridinium Units as Photosensitizers for Photoinactivation of Planktonic and Biofilm Forms of Escherichia coli (P-25)". Paper presented in The 5th Photodynamic Day, Virtual Meeting, 2021.
  16. Cláudia P. S. Ribeiro; Gamelas, Sara R. D.; Ana T.P.C. Gomes; Faustino, Maria; Almeida, Adelaide; TOME JOAO P C OR TOME JPC OR TOME J P C ; Leandro M. O. Lourenço. Corresponding author: Cláudia P. S. Ribeiro. "Unsymmetrical Cationic Porphyrin-Cyclodextrin Dyes for Photoinactivation of Escherichia coli (P-26)". Paper presented in The 5th Photodynamic Day, Virtual Meeting, 2021.
  17. Gamelas, S. R. D.; Rodrigues, João M. M.; Lourenço, Leandro; TOME JOAO P C OR TOME JPC OR TOME J P C . Corresponding author: Gamelas, S. R. D.. "Synthesis and Characterization of Ammonium-photosensitizers (QO14, pg. 10)". Paper presented in XXIV Encontro Luso-Galego de Química, Porto, Portugal, 2018.
  18. Gamelas, Sara; Ana T.P.C. Gomes; Faustino, Maria; Sousa, A.; Almeida, Adelaide; Cunha, Maria Ângela Sousa Dias Alves; Cavaleiro, José; M.G.P.M.S Neves. Corresponding author: Gamelas, Sara. "New Immobilized N-Confused Porphyrins: Synthesis and Biological Evaluation of their Antibacterial Activity (QO16, pg. 410)". Paper presented in XX Encontro Luso-Galego de Química, Porto, Portugal, 2014.
Journal article
  1. Sara R. D. Gamelas; Shayla Shmuel; Cristina Simó; Alex Vanover; João P. C. Tomé; Augusto C. Tomé; Leandro M. O. Lourenço; Patrícia M. R. Pereira. "Positron Emission Tomography and Optical Imaging to Monitor Bioorthogonal Diels–Alder Click Chemistry of Trastuzumab with a Porphyrin". Bioconjugate Chemistry (2025): https://doi.org/10.1021/acs.bioconjchem.5c00056.
    10.1021/acs.bioconjchem.5c00056
  2. Gamelas, S. R. D.; Bartolomeu, Maria; Vieira, Cátia; M. Amparo F. Faustino; TOME JOAO P C OR TOME JPC OR TOME J P C ; Tomé, Augusto C.; Almeida, Adelaide; Leandro M. O. Lourenço. "Bacterial Photodynamic Inactivation: Eradication of Staphylococcus aureus and Escherichia coli Mediated by Pyridinium-Pyrazolyl Zinc(II) Phthalocyanines". ACS Applied Bio Materials (2024): https://doi.org/10.1021/acsabm.4c01368.
    Published • 10.1021/acsabm.4c01368
  3. Sara R.D. Gamelas; Carla Pereira; M. Amparo F. Faustino; Adelaide Almeida; Leandro M.O. Lourenço. "Unveiling the potent Antimicrobial Photodynamic Therapy in Gram-positive and Gram-negative bacteria – Water remediation with monocharged chlorins". Chemosphere (2024): https://doi.org/10.1016/j.chemosphere.2024.143593.
    Published • 10.1016/j.chemosphere.2024.143593
  4. Gamelas, S. R. D.; Rodrigues, João M. M.; TOME JOAO P C OR TOME JPC OR TOME J P C ; Lourenço, Leandro. "Exploring the Spectral Properties and Potential Applications of Dimethylamine-modified Porphyrin and Chlorin Dyes". Journal of Photochemistry and Photobiology A: Chemistry 454 (2024): 115742. http://dx.doi.org/10.1016/j.jphotochem.2024.115742.
    Published • 10.1016/j.jphotochem.2024.115742
  5. Gamelas, S. R. D.; TOME JOAO P C OR TOME JPC OR TOME J P C ; Tomé, Augusto C.; Lourenço, Leandro. "Porphyrin-containing Materials for Photodegradation of Organic Pollutants in Wastewaters: a Review". Catalysis Science & Technology 14 9 (2024): 2352-2389. http://dx.doi.org/10.1039/d4cy00092g.
    Published • 10.1039/d4cy00092g
  6. Gamelas, S. R. D.; Bartolomeu, Maria; Gomes, Thierry J.; Faustino, Maria; TOME JOAO P C OR TOME JPC OR TOME J P C ; Tomé, Augusto C.; Almeida, Adelaide; Ana T.P.C. Gomes; Lourenço, Leandro. "Photodynamic Inactivation of a RNA-virus Model Using Water-soluble ß-octa-Substituted Pyridinium-Pyrazolyl Phthalocyanines". Dyes and Pigments 220 (2023): 111661. http://dx.doi.org/10.1016/j.dyepig.2023.111661.
    Published • 10.1016/j.dyepig.2023.111661
  7. Gamelas, S. R. D.; SIERRA-GARCIA, ISABEL N.; Tomé, Augusto C.; Cunha, Maria Ângela; Lourenço, Leandro. "In Vitro Photoinactivation of Fusarium oxysporum Conidia with Light-Activated Ammonium Phthalocyanines". International Journal of Molecular Sciences 24 4 (2023): 3922. http://dx.doi.org/10.3390/ijms24043922.
    Published • 10.3390/ijms24043922
  8. Gamelas, S. R. D.; TOME JOAO P C OR TOME JPC OR TOME J P C ; Tomé, Augusto C.; Lourenço, Leandro. "Advances in Photocatalytic Degradation of Organic Pollutants in Wastewaters: Harnessing the Power of Phthalocyanines and Phthalocyanine-containing Materials". RSC Advances 13 48 (2023): 33957-33993. http://dx.doi.org/10.1039/d3ra06598g.
    Published • 10.1039/d3ra06598g
  9. Gamelas, S. R. D.; Vieira, Cátia; Bartolomeu, Maria; Faustino, Maria; TOME JOAO P C OR TOME JPC OR TOME J P C ; Tomé, Augusto C.; Almeida, Adelaide; Lourenço, Leandro. "Photodynamic Inactivation of Pathogenic Gram-negative and Gram-positive bacteria Mediated by Si(IV) Phthalocyanines Bearing Axial Ammonium Units". Journal of Photochemistry and Photobiology B: Biology 233 (2022): 112502. http://dx.doi.org/10.1016/j.jphotobiol.2022.112502.
    Published • 10.1016/j.jphotobiol.2022.112502
  10. Gamelas, S. R. D.; Moura, Nuno M. M.; Habraken, Yvette; Piette, Jacques; M.G.P.M.S Neves; Faustino, Maria. "Tetracationic Porphyrin Derivatives Against Human Breast Cancer". Journal of Photochemistry and Photobiology B: Biology 222 (2021): 112258. http://dx.doi.org/10.1016/j.jphotobiol.2021.112258.
    Published • 10.1016/j.jphotobiol.2021.112258
  11. Gamelas, S. R. D.; Santos, Isabela; Vieira, Cátia; Faustino, Maria; TOME JOAO P C OR TOME JPC OR TOME J P C ; Almeida, Adelaide; Ana T.P.C. Gomes; Lourenço, Leandro. "Pyrazole-Pyridinium Porphyrins and Chlorins as Powerful Photosensitizers for Photoinactivation of Planktonic and Biofilm Forms of E. coli". Dyes and Pigments 193 (2021): 109557. http://dx.doi.org/10.1016/j.dyepig.2021.109557.
    Published • 10.1016/j.dyepig.2021.109557
  12. Gamelas, S. R. D.; Calmeiro, Joana M.D.; Ana T.P.C. Gomes; Faustino, Maria; M.G.P.M.S Neves; Almeida, Adelaide; TOME JOAO P C OR TOME JPC OR TOME J P C ; Lourenço, Leandro. "Versatile Thiopyridyl/Pyridinone Porphyrins Combined with Potassium Iodide and Thiopyridinium/Methoxypyridinium Porphyrins on E. coli Photoinactivation". Dyes and Pigments 181 (2020): 108476. http://dx.doi.org/10.1016/j.dyepig.2020.108476.
    Published • 10.1016/j.dyepig.2020.108476
  13. Cláudia P. S. Ribeiro; Gamelas, S. R. D.; Faustino, Maria; Ana T.P.C. Gomes; TOME JOAO P C OR TOME JPC OR TOME J P C ; Almeida, Adelaide; Lourenço, Leandro. "Unsymmetrical Cationic Porphyrin-Cyclodextrin Bioconjugates for Photoinactivation of Escherichia coli". Photodiagnosis and Photodynamic Therapy 31 (2020): 101788. http://dx.doi.org/10.1016/j.pdpdt.2020.101788.
    Published • 10.1016/j.pdpdt.2020.101788
  14. Gamelas, S. R. D.; Ana T.P.C. Gomes; Faustino, Maria; Tomé, Augusto C.; TOME JOAO P C OR TOME JPC OR TOME J P C ; Almeida, Adelaide; Lourenço, Leandro. "Photoinactivation of Escherichia coli with Water-Soluble Ammonium-Substituted Phthalocyanines". ACS Applied Bio Materials 3 7 (2020): 4044-4051. http://dx.doi.org/10.1021/acsabm.0c00128.
    Published • 10.1021/acsabm.0c00128
  15. Gamelas, S. R. D.; Ana T.P.C. Gomes; Moura, Nuno M. M.; Faustino, Maria; Cavaleiro, José; Lodeiro, Carlos; Veríssimo, Marta I.S.; et al. "N-Confused Porphyrin Immobilized on Solid Supports: Synthesis and Metal Ions Sensing Efficacy". Molecules 23 4 (2018): 867. http://dx.doi.org/10.3390/molecules23040867.
    Published • 10.3390/molecules23040867
  16. Mesquita, Mariana; Dias, Cristina J.; Gamelas, S. R. D.; Fardilha, Margarida; M.G.P.M.S Neves; Faustino, Maria. "An Insight on the Role of Photosensitizer Nanocarriers for Photodynamic Therapy". Anais da Academia Brasileira de Ciências 90 1 suppl 2 (2018): 1101-1130. http://dx.doi.org/10.1590/0001-3765201720170800.
    Published • 10.1590/0001-3765201720170800
Thesis / Dissertation
  1. "Synthesis of Phthalocyanines and Porphyrins for Energy Transfer Systems and Biomecial Applications". PhD, Universidade de Aveiro, 2024. https://ria.ua.pt/handle/10773/42312.
  2. "Synthesis of Porphyrin Derivatives to Assess the mRNA Alternative Splicing Induced by Photodynamic Therapy". Master, Universidade de Aveiro, 2016. https://ria.ua.pt/handle/10773/18633.
  3. "Novas Porfirinas N-confusas imobilizadas: Síntese e Avaliação Biológica". Degree, Universidade de Aveiro, 2014.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/07/15 Global Paths: Mobility Opportunities for PhD Students (Invited Speaker) AIM Further/Research Summit
University of Aveiro (Portugal)
2024/01/23 Bioorthogonal Pretargeting for Anchoring Photoactive BODIPY on the Plasma Membrane of HER2+ Gastric Tumours (presenter author, OC23) 15th National Organic Chemistry Meeting (ENQO) and 8th National Medicinal Chemistry Meeting (ENQT)
(Faro, Portugal)
2023/11/24 Enhancing Bacterial Photodynamic Inactivation through Combined Action of Potassium Iodide and Cationic Phthalocyanine (presenter author, QS28) XXVII Encontro Luso-Galego de Química
(Porto, Portugal)
2023/11/24 Synthesis and Delivery to Gastric Cancer Cells of a BODIPY-tetrazine through Click Chemistry (QS27) XXVII Encontro Luso-Galego de Química
(Porto, Portugal)
2023/07/24 Effective Light-Activated Photosensitizers for Photoinactivation of Microorganisms (FC3) XVIII Encontro Nacional da Sociedade Portuguesa de Química
(Aveiro, Portugal)
2022/11/17 Water-Soluble Pyrazole-Pyridinium Phthalocyanines for Photodynamic Inactivation of Phage Phi6 as SARS-CoV-2 Model (presenter author, QS31) XXVI Encontro Galego-Portugués de Química
(Santiago de Compostela, Spain)
2022/07/11 Porphyrin Photosensitizers for Biological Applications (S22) 12th International Conference on Porphyrins and Phthalocyanines (ICPP)
(Madrid, Spain)
2022/05/22 Axially Ammonium-Substituted Si(IV) Phthalocyanines as Efficient Photosensitizers for the Photodynamic Inactivation of Escherichia coli (presenter author, OC66) 14th National Organic Chemistry Meeting (ENQO) and 7th National Medicinal Chemistry Meeting (ENQT)
(Lisboa, Portugal)
2022/05/20 Photodynamic Activity of Porphyrin Derivatives: Synthesis and Applications (KN2) 14th National Organic Chemistry Meeting (ENQO) and 7th National Medicinal Chemistry Meeting (ENQT)
(Lisboa, Portugal)
2021/12/08 Cationic Phthalocyanine Derivatives and their Photodynamic Effect on Bacteria (O.19) 4th International Caparica Christmas Conference on Translational Chemistry (IC3CT)
(Lisboa, Portugal)
2021/12/06 Photoinactivation of Planktonic and Biofilm Forms of Escherichia coli through the Action of Pyrazole-Pyridinium Porphyrinoids (presenter author, SG|PSG15) 4th International Caparica Christmas Conference on Translational Chemistry (IC3CT)
(Lisboa, Portugal)
2021/10/21 Water Soluble Phthalocyanines Combined with Potassium Iodide for Efficient Photoinactivation of Escherichia coli (presenter author, Session 6) Iberian Symposium of Young Photochemists 2021 (ISYP2021) – Virtual Conference
(Alcalá de Henares , Spain)
2021/07/08 Supramolecular Phthalocyanine–Graphene and –Fullerene Hybrid Materials for Dye-sensitized Solar Cells (presenter author) Research Summit - Virtual Meeting
(Aveiro, Portugal)
2020/01/17 Photodynamic Inactivation of Escherichia coli using Neutral and Cationic Porphyrins (presenter author, OC22) 13th National Organic Chemistry Meeting (ENQO) and 6th National Medicinal Chemistry Meeting (ENQT)
(Aveiro, Portugal)
2020/01/17 Versatile Phthalocyanine Dyes as ‘Therapeutic Window’ for Photoinactivation of Microorganisms (OC29) 13th National Organic Chemistry Meeting and 6th National Medicinal Chemistry Meeting
(Aveiro, Portugal)
2019/11/21 Photoinactivation of Escherichia coli through Water-Soluble Ammonium-Phthalocyanines (presenter author, QS16) XXV Encontro Galego-Portugués de Química
(Santiago de Compostela, Spain)
2019/11/20 Photodynamic Inactivation of Antibiotic Resistant Bacteria using Cationic Porphyrins (QS04) XXV Encontro Galego-Portugués de Química, Santiago de Compostela
(Santiago de Compostela, Spain)
2018/11/22 Amphiphilic Porphyrins and Phthalocyanines as Potential Antimicrobial Agents (presenter author, QS6) XXIV Encontro Luso-Galego de Química
(Porto, Portugal)
2017/05/09 Materials Based on N-Confused Porphyrins: Synthesis, Characterization and Antimicrobial Photodynamic Inactivation (presenter author, CO.7) V National Meeting of Chemistry Students
(Coimbra, Portugal)
2016/11/10 Porphyrin Derivatives and mRNA Alternative Splicing Induced by Photodynamic Therapy (presenter author, QO5) XXII Encontro Luso-Galego de Química
(Bragança, Portugal)

Event organisation

Event name
Type of event (Role)
Institution / Organization
2024/05/02 - 2024/05/03 Knowledge Extension and Dissemination Activities: "Xperimenta – Workshops, Visits, Science Shows, and Experiments" (2024/05/02 - 2024/05/03)
Exhibition (Other)
Universidade de Aveiro, Portugal
2021/10/11 - 2021/10/17 Knowledge Extension and Dissemination activities: "Techdays - Exposition for the Scientific/General Community: Desenvolvimento de Moléculas Orgânicas com Caraterísticas Estruturais Adequadas para serem Utilizadas como Corantes em Células Solares" (2021/10/11 - 2021/10/17)
Exhibition (Member of the Organising Committee)
Techdays, Portugal
2020/01/15 - 2020/01/17 13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (2020/01/15 - 2020/01/17)
Conference (Other)
Universidade de Aveiro, Portugal
2019/10/10 - 2019/10/12 Knowledge Extension and Dissemination Activities: "Techdays - Exposition for the Scientific/General Community: Desenvolvimento de Moléculas Orgânicas usadas como Corantes em Células Solares" (2019/10/10 - 2019/10/12)
Exhibition (Member of the Organising Committee)
Techdays, Portugal
2018/10/11 - 2018/10/13 Knowledge Extension and Dissemination Activities: "Techdays - Exposition for the Scientific/General Community: Desenvolvimento de Moléculas Orgânicas usadas como Corantes em Células Solares” (2018/10/11 - 2018/10/13)
Exhibition (Member of the Organising Committee)
Techdays, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2024/11 - Current Dalton Transactions (1477-9234) RSC
2024/05 - 2024/05 Scientific Reports (2045-2322) Nature/Springer Nature
2024/04 - 2024/04 Scientific Reports (2045-2322) Nature/Springer Nature
2023/12 - 2023/12 Journal of Fluorescence (1573-4994) Springer Nature

Association member

Society Organization name Role
2023 - Current European Society for Molecular Imaging
2018 - Current Portuguese Chemical Society

Committee member

Activity description
Role
Institution / Organization
2013 - 2015 Semifinal and Final rounds of the Junior Chemistry Olympiads and Chemistry+ Olympiads (Organizing and staff committee)
Other
Sociedade Portuguesa de Química, Portugal

Mentoring / Tutoring

Topic Student name
2024/01 - 2024/07 Mentoring BsC Student in the Lab: "Inativação de Microrganismos Multi-resistentes: Uma Abordagem com Agentes Ativados pela Luz" Raquel Maria Alves Dias Tavares
2021/02 - 2021/07 Mentoring BsC Student in the Lab: "Fotoinativação de Microrganismos Usando Compostos Fotoativos" Andreia Filipa da Silva Peixoto
2019/02 - 2019/07 Mentoring BsC Student in the Lab: "Síntese de Derivados Porfírinicos e sua Aplicação em Fotoinativação de Microorganismos" Maria Isabela Pinho Santos
Distinctions

Award

2023 FLAD Grant R&D@USA 2023
Fundação Luso-Americana para o Desenvolvimento, Portugal
2023 Fulbright Grant: Bolsa Fulbright para Investigação com o apoio da FCT – 2022/2023
Fulbright Portugal, Portugal

Other distinction

2018 The article "N-Confused Porphyrin Immobilized on Solid Supports: Synthesis and Metal Ions Sensing Efficacy" was selected by the editors to appear on the cover of volume 23, issue 4