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Alexandra Cruz is a PhD student in Neurosciences at the Faculty of Medicine of the University of Porto. She is currently studying the neuronal mechanisms underlying obsessive and compulsive behaviors, under the supervision of Doctor Patrícia Monteiro. In 2020, she obtained the Master in Biomedical Research degree (Faculty of Medicine) and in 2018 she finished the Bachelor degree in Biochemistry (Faculty of Sciences and Technology), both at the University of Coimbra. She has contributed as a co-author to the publication of three original articles and an abstract in specialized journals, but also presented three oral communications and five posters in national and international conferences.
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Identification

Personal identification

Full name
Alexandra Filipa Figueiredo Cruz

Citation names

  • Cruz, Alexandra
  • Alexandra F. Cruz

Author identifiers

Ciência ID
1F1D-D3FA-C6DE
ORCID iD
0000-0002-6027-7285

Email addresses

  • affcruz@hotmail.com (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Behavioural Sciences Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Cell Biology
  • Medical and Health Sciences - Clinical Medicine - Psychiatry
  • Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
German Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Spanish; Castilian Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2022/09/12 - 2027
Ongoing
 PhD in Neuroscience (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
2021/10/09 - 2021/11/20
Concluded
 Statistical analysis of Data with SPSS (Curso de Especialização Tecnológica)
Universidade de Coimbra Faculdade de Economia, Portugal
 18
2021/02 - 2021/06
Concluded
 Spanish Language and Culture (A1) (Outros)
Universidade de Coimbra Faculdade de Letras, Portugal
 18
2018/09 - 2020/12
Concluded
 Master in Biomedical Research (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
"Microglia Morphology and Behavior upon Testosterone Administration of Females Prenatally Exposed to Dexamethasone " (THESIS/DISSERTATION)
 18
2019/11/04 - 2019/11/15
Concluded
 Modular Training in Laboratory Animal Science (Function A) (Outros)
CNC.IBILI, Portugal
 18
2018/09 - 2019/06
Concluded
 German Language and Culture (A1) (Outros)
Universidade de Coimbra Faculdade de Letras, Portugal
 17
2017/09 - 2018/06
Concluded
 English Language and Culture (C1) (Outros)
Universidade de Coimbra Faculdade de Letras, Portugal
 18
2015 - 2018
Concluded
 Bachelor Degree in Biochemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
 15
Affiliation

Science

Category
Host institution 		Employer
2022/03 - 2022/08 Research Trainee (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2021/04/01 - 2021/08/31 Researcher (Research) Universidade de Coimbra Faculdade de Medicina, Portugal
CNC.IBILI, Portugal
Outputs

Publications

Conference abstract
  1. Cruz, A; Simões-Henriques, C; Ferreira, AS (5F17-89EE-7543); Galvão, S; Rodrigues-Neves AC (4F10-888E-7CA9); Gaspar, Rita (DE17-CC9B-3F5F); A.F. Ambrosio (4E11-2573-20FE); Catarina A. Gomes (A019-E82E-442A); Baptista, FI (241E-D1C2-2DF7). "Influence of Prenatal Exposure to Dexamethasone on Neurodevelopmental Behaviour". Paper presented in Health 4.0: Designing Tomorrow's Healthcare, 2020.
    Published • 10.1093/eurpub/ckaa040.034
Conference poster
  1. Alexandra F. Cruz; Rodrigues, Diana; Marques, Fernanda; Monteiro, Patricia. "Deletion of immune protein LCN2 causes impairments in striatal circuits and OCD-like behaviors in mice". Paper presented in FENS Regional Meeting 2023, 2023.
  2. Alexandra F. Cruz; Boia, Raquel; Gaspar, Rita; Nunes, Sara; Baptista, FI (241E-D1C2-2DF7); António Francisco Ambrósio. "Assessment of the impact of an early acute immune challenge on the diabetic retina". Paper presented in XXIII EVER Congress, 2022.
  3. Cruz, Alexandra; Boia, Raquel; Gaspar, Rita; Sara Nunes; Baptista, FI; António Francisco Ambrósio; Hugo Fernandes. "Assessment of the impact of an early acute immune challenge on the diabetic retina". Paper presented in The Biochemistry Global Summit, 2022.
  4. Cindy Bokobza; Alice Jacquens; David Guenoun; Blandine Bianco; Anne Galland; Maxime Pispisa; Alexandra F. Cruz; et al. "Targeting the brain 5-HT7 receptor to prevent hypomyelination in a rodent model of perinatal white matter injuries". Paper presented in FENS, 2022.
  5. António Francisco Ambrósio; Alexandra F. Cruz; Boia, Raquel; Gaspar, Rita; Nunes, Sara; Baptista, FI. "Impact of an Early Immune Challenge on the Retinal Dysfunction upon a Secondary Chronic Diabetic Insult". Paper presented in XVII Reunião da Sociedade Portuguesa de Neurociências, 2021.
Journal article
  1. Rodrigues, Diana; Jacinto, Luis; Falcão, Margarida; Castro, Ana ; Alexandra F. Cruz; Santa, Cátia; 181C-7EE9-1F7E; et al. "Chronic stress causes striatal disinhibition mediated by SOM-interneurons in male mice". Nature Communications 13 1 (2022): http://dx.doi.org/10.1038/s41467-022-35028-4.
    Published • 10.1038/s41467-022-35028-4
  2. Bokobza, Cindy; Jacquens, Alice; Guenoun, David; Bianco, Blandine; Galland, Anne; Pispisa, Maxime; Cruz, Alexandra; et al. "Targeting the brain 5-HT7 receptor to prevent hypomyelination in a rodent model of perinatal white matter injuries". Journal of Neural Transmission (2022): http://dx.doi.org/10.1007/s00702-022-02556-8.
    Open access • Published • 10.1007/s00702-022-02556-8
  3. Sousa, Fábio J.; Correia, Raquel G.; Cruz, Alexandra F.; Martins, Joana M.; Rodrigues, Matilde S.; Gomes, Catarina A.; Ambrósio, António F.; Baptista, Filipa I.. "Sex differences in offspring neurodevelopment, cognitive performance and microglia morphology associated with maternal diabetes: Putative targets for insulin therapy". Brain, Behavior, & Immunity - Health 5 (2020): 100075. http://dx.doi.org/10.1016/j.bbih.2020.100075.
    10.1016/j.bbih.2020.100075
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/02/18 Physiological Sex Differences in Microglia and Behavior: Organizational Effects of Testosterone LI Reunião da Sociedade Portuguesa de Farmacologia, XXXIX Reunião de Farmacologia Clínica e XX Reunião de Toxicologia
Faculdade de Farmácia da Universidade de Lisboa (Lisboa, Portugal)
2020/06/26 Influence of Prenatal Exposure to Dexamethasone on Neurodevelopmental Behavior Annual Meeting 2020: Saúde 4.0: Desenhar a Saúde de Amanhã
Escola Superior de Tecnologia da Saúde de Coimbra (Coimbra, Portugal)
2020/02/07 Prenatal Exposure to Dexamethasone Improves Offspring Development in a Sex-Independent Manner L Reunião da Sociedade Portuguesa de Farmacologia, XXXVIII Reunião de Farmacologia Clínica e XIV Reunião de Toxicologia
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)

Mentoring / Tutoring

Topic Student name
2021/03 - 2021/07 Does an infection early in life modulate the severity of diabetic retinopathy in adulthood? Ângela Soares
2021/03 - 2021/07 Immune Memory: How an Early Infection Can Affect the Severity of Diabetic Retinopathy in Adulthood? Rita Pais
2021/03 - 2021/07 How can an Infection Early in Life Impact the Onset of Diabetic Retinopathy? João Lourenço