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Miguel Lino (ML) is a researcher at the University of Coimbra and affiliated with the Centre for Innovative Biomedicine and Biotechnology (CIBB). He has an MSc in Biomedical Engineering (IST, University of Lisbon) and a PhD in Biosciences (University of Coimbra, 2017). ML has acquired strong expertise in different fields of knowledge: biomedical engineering, biology, biomaterials and nanotechnology. In his PhD and in the following years, ML made a significant contribution to the development of a cutting-edge research field in the lab of Dr Lino Ferreira, related to the creation of light-triggerable formulations for the intracellular delivery of biomolecules. The work gave origin to one international patent (PCT/IB2016/056229) and publications in prestigious nanotechnology journals (ACS Nano, Nanoscale), which have been highlighted by the national press. In his postdoctoral career, ML has worked on the development of sEV therapeutics for the treatment of cardiovascular/brain disorders, mainly focused on ischemic diseases and sEV targeting strategies. Several articles in high-impact journals (J. of Controlled Release, J. of Extracellular Vesicles, ACS Nano, Nanoscale) have already resulted from his contribution to this field. Overall, he published 19 articles in peer-reviewed journals (all in Q1; average IF>9.4). In the last 4 years, ML was able to increase his scientific independence. From 2020 until 2021, ML was an invited auxiliary researcher at the Faculty of Medicine of the University of Coimbra. Since 2021 he was able to secure: (i) a contract of junior researcher in the national call for Scientific Employment Stimulus (top 8%); (ii) funding as PI and co-PI for FCT exploratory projects (100k €) on sEV-based therapeutics; (iii) funding for two research stays at Imperial College London. Over the years, he has supervised 2 PhD students, a team of 4 researchers (1 postdoc and 3 MSc fellows) dedicated to sEV therapies, 3 researchers (1 postdoc and 2 MSc fellows) working on sEVs to reverse cell senescence and he has mentored 6 visiting students/researchers. In the last years, he has built a network of contacts with international experts from top institutions: Dr Costanza Emanueli and Dr Césare Terracciano (Imperial College London), Dr Tomas Sobrino (University of Santiago de Compostela), Dr Ana Teixeira (Karolinska Institute), Dr Diana Nascimento (i3S) and Dr Chiara Brovarone (Polytechnic University of Turin). Besides his research activities, he is an invited professor of the syllabus “Regenerative Medicine” of the MSc program in Biomedical Engineering (Univ. Coimbra) and has contributed with lectures for the PhD programme in Biomedicine and Experimental Biology (CNC-UC). From 2019 until 2023, he was the coordinator of the section “Cell Therapies and Tissue Engineering” of the Portuguese Society for Stem Cells and Cell Therapies and since 2023 he is a member of the scientific council of the Multidisciplinary Institute of Ageing. His scientific contributions have been recognized at national and international levels: he has been invited to be a jury member in 4 MSc defences and 4 PhD defences; he gave talks at conferences/symposiums (6 by invitation, 1 keynote lecture); He received 5 poster awards at international conferences. He was invited to be an abstract reviewer for the 7th TERMIS World Congress and to become a review editor of Frontiers in Medical Engineering. He has acted as a reviewer for different journals (ACS Biomaterials Science & Engineering; Cells).
Identification

Personal identification

Full name
Miguel Maria da Fonseca Miranda Ferreira Lino

Citation names

  • Lino, Miguel

Author identifiers

Ciência ID
1C1F-4287-AF90
ORCID iD
0000-0001-6011-0058

Knowledge fields

  • Engineering and Technology - Nano-technology - Nano-materials
  • Medical and Health Sciences - Medical Biotechnology - Biomaterials
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Portuguese (Mother tongue)
Education
Degree Classification
2017
Concluded
PhD in Biosciences, Specialization in biotechnology (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Light-triggerable Nanomaterials for the Delivery of Biomolecules" (THESIS/DISSERTATION)
Approved with praise and distinction
2007
Concluded
Integrated Masters in Biomedical Engineering (Mestrado)
Universidade de Lisboa, Portugal
"Análise ecográfica, estrutural e biomecânica de tendões" (THESIS/DISSERTATION)
17
Affiliation

Science

Category
Host institution
Employer
2022/06/01 - Current Researcher (Research) Universidade de Coimbra, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
2021/06/01 - 2022/05/31 Invited Auxiliary Researcher (Research) Faculty of Medicine of the University of Coimbra, Portugal
2022/02 - 2022/04 Visiting Researcher (Research) Faculty of Medicine of the University of Coimbra, Portugal
Imperial College London, United Kingdom
2021/08/01 - 2021/09/25 Visiting Researcher (Research) Faculty of Medicine of the University of Coimbra, Portugal
Imperial College London - Hammersmith Campus, United Kingdom
2018/10/01 - 2021/03/31 Contracted Researcher (Research) Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal

Others

Category
Host institution
Employer
2021/03/01 - 2021/05/31 Scientific report writer (responsible for the elaboration of the periodic and final technical reports of the ERA@UC project) Faculty of Medicine of the University of Coimbra, Portugal
Faculty of Medicine of the University of Coimbra, Portugal
2017/11/01 - 2018/09/30 Post-doctoral researcher (project ERA@UC) CNC.IBILI, Portugal
2016/02/01 - 2017/10/31 Research assistant (project Nanotrigger ERC Grant Agreement nº 307384) CNC.IBILI, Portugal
2012/01/01 - 2017/06/20 PhD student (Doctoral program in Biosciences, Specialization in biotechnology) Universidade de Coimbra, Portugal
2009/09/01 - 2011/12/31 Research assistant. Development of antimicrobial nanomaterials and coatings for biomedical application Matera Lda, Portugal
Projects

Grant

Designation Funders
2021/05 - Current Synaptic regulation by chronic stress-induced microRNA-186-5p in the prefrontal cortex
HR21-01077
Researcher
Obra Social La Caixa
Ongoing
2017/11/01 - 2018/09/30 ERA@UC. Ref 669088. ERA Chair in Cellular and Molecular Biology of Ageing
Post-doc Fellow
European Commission
Ongoing

Contract

Designation Funders
2023/01/01 - Current Design and development of polymer brush functionalized exosomes for brain targeted delivery of miRNA
2022.02803.PTDC
Co-Principal Investigator (Co-PI)
2022/01/01 - Current A gene-editing nanoparticle formulation for retinal degeneration diseases
EXPL/BIA-CEL/0989/2021
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - Current Engineered extracellular vesicles for neuroprotection
EXPL/BTM-ORG/1348/2021
Principal investigator
Fundação para a Ciência e a Tecnologia
Ongoing
2018/10/01 - Current EXO-HEART: Protecção e regeneração cardíaca mediada pela administração sistémica e direcionada de exosomas.
PTDC/BTM-SAL/29919/2017
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/06 - Current A light-activatable nanoparticle library for the delivery of RNA-based therapies
PTDC/EQU-EQU/29414/2017
Post-doc
CNC.IBILI, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2016 - 2019 Plataformas terapêuticas para acidentes vasculares cerebrais
SII&DT 3386 StrokeTherapy
Researcher
Concluded

Other

Designation Funders
2012/11/01 - 2017/06/20 Triggerable nanomaterials to modulate cell activity
307384
PhD Student Fellow
CNC.IBILI, Portugal
European Research Council
Concluded
2010 - 2012 Antimicrobial coatings and materials based in polycationic polymers
0000
Researcher
IAPMEI
Outputs

Publications

Conference abstract
  1. Lino, Miguel; Rondão, Tiago; Banerjee, A; Aires, I; Rodrigues, M; Fernandes, Dominique; Freitas, J; et al. "Extracellular Vesicles Secreted by Mononuclear Cells from Umbilical Cord Blood Induce Neuroprotection and Angiogenesis and Attenuate Microglia Reactivity in a Mouse Model of Brain Ischemia". Paper presented in European Journal of Clinical Investigation, 2022.
    Published
Conference paper
  1. Henriques-Antunes H; Renato Cardoso; Alessandra Zonari; Joana Correia; Leal, Ermelindo C; Adrien Jimenez-Balsa; Lino, Miguel; Gomes, Célia. "Oral Talks - Orchestrating the release of small extracellular vesicles with a light-triggerable hydrogel". 2020.
    10.1111/eci.13108
Conference poster
  1. Cláudia M. Deus; Soares, Susana; Ferreira-Rodrigues, M; Rai, Akhilesh; Lino, Miguel; Ferreira, Lino. Corresponding author: Cláudia M. Deus. "To reset the senescence program in senescent stem/progenitor cells by extracellular vesicles". Paper presented in 33rd Annual Conference of the European Society for Biomaterials, 2023.
  2. Miguel Lino. "Small extracellular vesicles for increased neuroprotection and modulation of microglia reactivity in stroke". Paper presented in 2nd Meeting of the Portuguese Network on Extracellular Vesicles, 2023.
  3. Miguel Lino. "Extracellular vesicles for neuroprotection and modulation of microglia reactivity in stroke". Paper presented in Joint Meeting ETRS & SPCE-TC, 2023.
  4. Magda Ferreira Rodrigues; Ana Carolina Mendes; Susana Soares; Eduardo Pires; Akhilesh Rai; Miguel Lino; Lino Ferreira. Corresponding author: Miguel Lino. "Freeze-dried small extracellular vesicles (sEVs): the next step for sEV clinical applications". Paper presented in Biosystems in Toxicology and Pharmacology meeting., 2022.
  5. Inês Albino; Miguel Lino; Francesco Catapano; Costanza Emanueli; Lino Ferreira. Corresponding author: Miguel Lino. "Engineered extracellular vesicles targeting ischemic endothelial cells". Paper presented in 12th International Meeting of the ¿Portuguese Society for Stem Cells ¿and Cell Therapies, 2022.
  6. Inês Albino; Miguel Lino; Lino Ferreira. Corresponding author: Miguel Lino. "Engineered Extracellular Vesicles for Brain Targeting and Modulation". Paper presented in ESB-NANOSTEM Joint Sympoium, 2021.
  7. Lino, Miguel. "Lignt-controlled systems for the delivery of microRNAs". Paper presented in 4th COST Action CardioRNA MC and WG Meeting, 2020.
  8. Lino, Miguel. "Orchestrating the release of small extracellular vesicles with a light-triggerable hydrogel". Paper presented in ESCI 2019, 2019.
  9. Lino, Miguel; Susana Simões; Andreia Vilaça; Helena Antunes; Lino Ferreira. "Near-infrared triggered release of miRNAs for modulation of cell activity". Paper presented in XII Spanish-Portuguese Conference on Controlled Drug Delivery, 2018.
  10. Lino, Miguel; Susana Simões; Andreia Vilaça; Helena Henriques-Antunes; Alessandra Zonari; Lino Ferreira. "Spatio-temporal controlled delivery of miRNAs for modulation of angiogenic activity". Paper presented in 10th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, 2017.
  11. Lino, Miguel; Susana Simões; Andreia Vilaça; Helena Antunes; Alessandra Zonari; Lino Ferreira. "Modulation of cell activity by light-controlled delivery of miRNAS". Paper presented in 6th China-Europe Symposium on Biomaterials and Regenerative Medicine, 2017.
  12. Miguel Lino. "Light-controlled release of proteins from gold nanorods". Paper presented in 3rd Symposium in Nanoscience and Biomedical Nanotechnology, 2016.
Journal article
  1. Susana Simões; Lino, Miguel; Angela Barrera; Catarina Rebelo; Francesca Tomatis; Andreia Vilaça; Christopher Breunig; et al. "Near infrared light-activated formulation for the spatial controlled release of CRISPR-Cas9 ribonucleoprotein for brain gene editing". Angewandte (2024):
    In press
  2. Andreia Vilaça; Miguel Lino; Hugo Fernandes; Leon de Windt; Lino Ferreira. "Extracellular vesicle transfer of lncRNA H19 splice variants to cardiac cells". Molecular Therapy - Nucleic Acids (2024):
    Under revision
  3. Arnab Banerjee; Lino, Miguel; Carlos Jesus; Quélia Ribeiro; Antero Abrunhosa; Lino Ferreira. "Imaging platforms to dissect the in vivo communication, biodistribution and controlled release of extracellular vesicles". Journal of Controlled Release 360 (2023): 549-563. https://www.sciencedirect.com/science/article/abs/pii/S0168365923004224.
    Published
  4. João André Sousa; Catarina Bernardes; Sara Bernardo-Castro; Miguel Lino; Inês Albino; Lino Ferreira; José Brás; et al. "Reconsidering the role of blood-brain barrier in Alzheimer’s disease: From delivery to target". Frontiers in Aging Neuroscience 15 (2023): https://doi.org/10.3389/fnagi.2023.1102809.
    Published
  5. Lino, Miguel; Rondão, Tiago; Arnab Banerjee; Inês Aires; Magda Rodrigues; Tiago Reis; António Santinha; et al. "Small extracellular vesicles administered directly in the brain promote neuroprotection and decrease microglia reactivity in a stroke mouse model". Nanoscale (2023): https://pubs.rsc.org/en/content/articlelanding/2023/nr/d3nr03861k.
    Published
  6. Fernandes, Hugo; Alessandra Zonari; Ricardo Abreu; Sezin Aday; Barão, Marta; Inês Albino; Miguel Lino; et al. "Extracellular vesicles enriched with an endothelial cell pro-survival microRNA impacts skin tissue regeneration". Molecular Therapy - Nucleic Acids (2022): https://doi.org/10.1016/j.omtn.2022.03.018.
    Published
  7. Akhilesh Rai; Rafaela Ferrão; Denise Marta; Andreia Vilaça; Lino, Miguel; Tiago Rondão; Artur Paiva; Lino Ferreira. "Antimicrobial peptide-tether dressing able to enhance wound healing by tissue contact". ACS Applied Materials & Interfaces (2022): https://doi.org/10.1021/acsami.2c06601.
    Published
  8. Lino, Miguel; Susana Simões; Francesca Tomatis; Inês Albino; Angela Barrera; Denis Vivien; Tomas Sobrino; Lino Ferreira. "Engineered extracellular vesicles as brain therapeutics". Journal of Controlled Release (2021): https://doi.org/10.1016/j.jconrel.2021.08.037.
    Published
  9. Ricardo C. Abreu; Cristiana V. Ramos; Clarissa Becher; Miguel Lino; Carlos Jesus; Paula A. Costa Martins; Patrícia A. T. Martins; et al. "Exogenous loading of miRNAs into small extracellular vesicles". Journal of Extracellular Vesicles 10 10 (2021): https://doi.org/10.1002%2Fjev2.12111.
    Published • 10.1002/jev2.12111
  10. Sara Bernardo-Castro; Inês Albino; Ángela María Barrera-Sandoval; Francesca Tomatis; João André Sousa; Emanuel Martins; Susana Simões; et al. "Therapeutic Nanoparticles for the Different Phases of Ischemic Stroke". Life 11 6 (2021): 482-482. https://doi.org/10.3390%2Flife11060482.
    10.3390/life11060482
  11. Francisco, Vitor; Lino, Miguel; Ferreira, Lino. "A near infrared light-triggerable modular formulation for the delivery of small biomolecules". Journal of Nanobiotechnology 17 1 (2019): http://dx.doi.org/10.1186/s12951-019-0530-y.
    10.1186/s12951-019-0530-y
  12. Helena Henriques-Antunes; Renato M. S. Cardoso; Alessandra Zonari; Joana Correia; Ermelindo C. Leal; Adrián Jiménez-Balsa; Miguel M. Lino; et al. "The Kinetics of Small Extracellular Vesicle Delivery Impacts Skin Tissue Regeneration". ACS Nano (2019): https://doi.org/10.1021/acsnano.9b00376.
    10.1021/acsnano.9b00376
  13. Arnab Banerjee; Vitor Alves; Tiago Rondão; José Sereno; Ângela Neves; Miguel Lino; Andreia Ribeiro; Antero J. Abrunhosa; Lino S. Ferreira. "A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles". Nanoscale 11 28 (2019): 13243-13248. https://doi.org/10.1039/C9NR02512J.
    10.1039/C9NR02512J
  14. Banerjee, Arnab; Rondao, Tiago; Sereno, Jose; Alves, Vitor; Lino, Miguel; Ribeiro, Andreia; Abrunhosa, Antero; Ferreira, Lino. "PET imaging and in vivo bio-distribution of small extracellular vesicles". European Journal of Clinical Investigation (2019): https://publons.com/wos-op/publon/53879095/.
  15. Miguel M. Lino; Susana Simões; Andreia Vilaça; Helena Antunes; Alessandra Zonari; Lino Ferreira. "Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers". ACS Nano (2018): https://doi.org/10.1021/acsnano.7b07538.
    10.1021/acsnano.7b07538
  16. Adrián Jiménez-Balsa; Sandra Pinto; Emanuel Quartin; Miguel M. Lino; Vitor Francisco; Lino Ferreira. "Nanoparticles Conjugated with Photocleavable Linkers for the Intracellular Delivery of Biomolecules". Bioconjugate Chemistry (2018): https://doi.org/10.1021%2Facs.bioconjchem.7b00820.
    10.1021/acs.bioconjchem.7b00820
  17. Miguel M. Lino; Lino Ferreira. "Light-triggerable formulations for the intracellular controlled release of biomolecules". Drug Discovery Today (2018): https://doi.org/10.1016%2Fj.drudis.2018.01.019.
    10.1016/j.drudis.2018.01.019
  18. Miguel M. Lino; Susana Simões; Sónia Pinho; Lino Ferreira. "Intracellular delivery of more than one protein with spatio-temporal control". Nanoscale (2017): https://doi.org/10.1039/C7NR02414B.
    10.1039/C7NR02414B
  19. Miguel M. Lino; Cristiana S.O. Paulo; Ana C. Vale; M. Fátima Vaz; Lino S. Ferreira. "Antifungal activity of dental resins containing amphotericin B-conjugated nanoparticles". Dental Materials 29 10 (2013): e252-e262. https://doi.org/10.1016%2Fj.dental.2013.07.023.
    10.1016/j.dental.2013.07.023
  20. Lino, Miguel. "Differential internalization of amphotericin B – Conjugated nanoparticles in human cells and the expression of heat shock protein 70". Biomaterials 34 21 (2013): 5281-5293. http://www.sciencedirect.com/science/article/pii/S014296121300358X.
    https://doi.org/10.1016/j.biomaterials.2013.03.048
  21. D. Botequim; J. Maia; M. M. F. Lino; L. M. F. Lopes; P. N. Simões; L. M. Ilharco; L. Ferreira. "Nanoparticles and Surfaces Presenting Antifungal, Antibacterial and Antiviral Properties". Langmuir 28 20 (2012): 7646-7656. https://doi.org/10.1021%2Fla300948n.
    10.1021/la300948n
Thesis / Dissertation
  1. Lino, Miguel. "Light-triggerable nanomaterials for the delivery of biomolecules". PhD, Universidade de Coimbra, 2017.

Intellectual property

Patent
  1. Lino, Miguel. 2017. "composition for controlled release of a biomolecule, method of preparation and uses thereof". Portugal.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/09 Engineering of extracellular vesicles for tissue engineering 33rd Annual Conference of the European Society for Biomaterials
(Davos)
2023/05/12 Engineered extracellular vesicles for the treatment of ischemic diseases (Invited Speaker) Workshop - ICNAS Pharma
ICNAS (Coimbra, Portugal)
2022/06/10 Extracellular vesicles secreted by mononuclear cells from umbilical cord blood induce neuroprotection and angiogenesis and attenuate microglia reactivity in a mouse model of brain ischemia ESCI 2022
European Society for Clinical Investigation (Bari, Italy)
2022/05/27 Engineered extracellular vesicles targeting the ischemic myocardium (Invited speaker) 8th COST Action CardioRNA MC and WG Meeting
COST Action CardioRNA (Pavia, Italy)
2022/03/11 Engineering strategies to boost the therapeutic potential of extracellular vesicles (Invited speaker) XII International Meeting of the Portuguese Society for Stem Cells and Cell Therapies
Portuguese Society for Stem Cells and Cell Therapies (Braga)
2021/03/04 Light-controlled delivery of biomolecules (Invited speaker) XVI ENEEB - National Biomedical Engineering Student Symposium
(Portugal)
2020/07/15 Advanced formulations for the delivery of biomolecules (Invited speaker) 2nd NanoStem Summer School
University of Coimbra (Coimbra, Portugal)
2019/12/19 Modulation of microRNA Delivery with Light (Invited speaker) CiBB meeting 2019
CiBB (Coimbra, Portugal)
2019/07 Controlled release of small extracellular vesicles by a light-triggerable hydrogel improves diabetic wound healing Controlled Release Society, Annual Meeting and Exposition
CRS (Valência, Spain)
2019/05 Orchestrating the release of small extracellular vesicles with a light-triggerable hydrogel 53rd Annual Scientific Meeting of the European Society for Clinical Investigation
ESCI (Coimbra, Portugal)
2019/05 What is needed from preclinical research to set up a clinical trial (Invited speaker) 53rd Annual Scientific Meeting of the European Society for Clinical Investigation
ESCI (Coimbra, Portugal)
2019/05 PET imaging and in vivo biodistribution of small extracellular vesicles 53rd Annual Scientific Meeting of the European Society for Clinical Investigation
ESCI (Coimbra, Portugal)
2019/01/19 Controlled drug release systems Advanced workshop on biotechnology
Instituto de Educação e Cidadania (Portugal)
2018/12 Improved wound healing activity of small extracellular vesicles loaded in a light-triggerable hydrogel Secretome Without Borders
(Braga, Portugal)
2018 Controlling drug delivery with light (Invited speaker) IV Symposium of the Doctoral Program on Molecular and Environmental Biology,
(Braga, Portugal)
2016/07 Light controlled protein delivery German-Portuguese Student Workshop within the DAAD-Programme “Dialogue with Institutions of Higher Education in Southern Europe”
Biomaterials and Stem Cell based therapeutics Lab (Cantanhede, Portugal)
2016/05 Modulating protein delivery by opto-nanomedicine 10th World Biomaterials Congress,
(Montreal, Canada)
2015/10 Modulating cell activity by opto-nanomedicine 9th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies
(Oeiras, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2022/09 - Current Combinatorial intervention to treat myocardial infarction
Co-supervisor of Ana Carolina Mendes
2018/09/01 - Current New platforms for brain targeting by extracellular vesicles
Co-supervisor of Inês Maria Cunha Albino
Universidade de Coimbra, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2023/09/08 - Current Symposium "Extracellular Vesicle Bioengineering", 33rd Annual Conference of the European Society for Biomaterials, Davos, 2023 (Keynote speaker) (2023/09/08)
Symposium (Co-organisor)
2016/06/27 - Current Stem cell workshop: from basic research to clinical applications, Centro Hospitalar da Universidade de Coimbra, Portugal, June 27 th 2016. (2016/06/27)
Workshop (Member of the Organising Committee)
2014/03 - Current Workshop on Stem cells: from basic research to therapeutic applications, Centro do Sangue e Transplantação de Coimbra, Coimbra, Portugal, March 24 th , 2014. (2014/03/24)
Workshop (Co-organisor)
2013/12 - Current German-Portuguese student Workshop on “Matrix Engineering meets Stem Cell Therapy”, Biocant, Cantanhede, Portugal, December 2013. (2013/12)
Workshop (Co-organisor)
2013/07/19 - Current First International Conference on Stem Cells for Drug Screening and Regenerative Medicine, Biocant, Cantanhede, Portugal, July 19 th , 2013. The meeting had the contribution of renowned speakers including Jeffrey Karp (Harvard University), Molly Stevens (Imperial College of London), Pedro Granja (INEB, University of Porto, Portugal), Stephen Minger (GE Healthcare, UK), Tim Allsop (Pfizer), Joaquim Cabral (IST, Portugal), Constanza Emanueli (University of Bristol), Marc Peschanski (I-STEM) and Ihor Lemischka (Mount Sinai School of Medicine). (2013/07/19)
2021/06/30 - 2021/06/30 1st RESETageing conference (2021/06/30)
Conference (Member of the Organising Committee)
2019/06/28 - 2019/06/29 Conference: Ageing, models mechanisms and therapies. Responsible for the dissemination of the event in the media. (2019/06/28 - 2019/06/29)
Conference (Member of the Organising Committee)
Universidade de Coimbra, Portugal
2018/07/27 - 2018/07/27 Workshop on “Ageing: models and therapies”, Faculty of Medicine, University of Coimbra, Polo III, June 27 th , 2018. (2018/07/27)
Workshop (Member of the Organising Committee)
Universidade de Coimbra, Portugal
2016/07/07 - 2016/07/08 German-Portuguese student Workshop on “Translation in Biomaterials and Stem Cell Research”, Biocant, Cantanhede, Portugal, July 7-8 2016. The event was organized in collaboration with Dr. Tilo Pompe from the University of Leipzig, Germany, and funded by the DAAD program “Dialogue with Institutions of Higher Education in Southern Europe”. (2016/07/07 - 2016/07/08)
Workshop
Universidade de Coimbra, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2016/07/18 - 2016/07/22 Building Global innovators (Innovation accelerator) – Entrepreneurship course
Other
Building Global Innovators
ISCTE Business School, Portugal
2015/10/05 - 2015/10/09 Quantitative Fluorescence Microscopy Course
Workshop
Quantitative Fluorescence Microscopy Course
CNC.IBILI, Portugal
2009/11/02 - 2009/11/07 7th International Stem Cell School in Regenerative Medicine
Workshop

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2023/07/05 MicroRNAs-enriched exosomes as a new therapy for Parkinson’s disease.
(Thesis) Main arguer
Marta Carrola Esteves (PhD)
Universidade da Beira Interior, Portugal
2023/04/06 Synaptic regulation by chronic stress-induced microRNAs
(Thesis) Arguer
Beatriz Figueired Rodrigues (PhD)
Universidade de Coimbra, Portugal
2022/09/30 Radiolabelling of Small Extracellular Vesicles for Diagnostics and Therapeutic Applications
(Thesis) Main arguer
Francisco Tejo (Master)
Universidade de Coimbra, Portugal
2022/09/23 Nanoformulations for the treatment of vascular ageing
(Thesis) Main arguer
Joana Padrão (Master)
Universidade de Coimbra, Portugal
2022/03/30 Vascular cell senescence: Triggers and therapeutic strategies
(Thesis) Arguer
Rita Sá Ferreira (PhD)
Universidade Nova de Lisboa, Portugal
2021/01/11 Biocompatible Nanoparticles to Modulate Cell Activity
(Thesis) Arguer
Josephine Blersch (PhD)
Universidade de Coimbra, Portugal
2018/12 Funcionalização de filmes finos plasmónicos de Au-TiO2 com elementos de bioreconhecimento para deteção de biomoléculas
(Thesis) Main arguer
Diana Isabela Faria Meira (Master)
Universidade do Minho, Portugal
2018/12 Development of ZnO thin films for antimicrobial applications
(Thesis) Main arguer
Patrícia Alexandra Pereira da Silva (Master)
Universidade do Minho, Portugal

Association member

Society Organization name Role
2017/10 - Current Controlled Release Society

Committee member

Activity description
Role
Institution / Organization
2019/07 - Current Coordinator of the section Stem Cells and Tissue Engineering
Coordinator

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018/09/01 - Current Regenerative Medicine Ciências de Engenharia Biomédica (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/01/12 - 2019/03/16 Biotechnology and Regenerative Medicine (Outros) Instituto de Educação e Cidadania, Portugal

Interview (tv / radio show)

Program Topic
2019/01/29 - 2019/01/29 Rádio França Internacional - Magazine de Ciência

Mentoring / Tutoring

Topic Student name
2022/12/01 - Current Extracellular vesicles to reverse cell senescence Cláudia Deus (Postdoctoral researcher)
2022/03 - Current Study of anti-senescence properties of extracellular vesicles Susana Soares (MSc fellow)
2022/02/01 - Current Neuroregeneration mechanisms of extracellular vesicles Magda Rodrigues (MSc felllow)
2022/07/01 - 2022/08/31 Extracellular vesicles targeting ischemic endothelial cells Juliana Floriano (Visiting postdoctoral researcher)
2022/06 - 2022/08 Interaction of nanogels with the blood brain barrier Roberta Bilardo (Visiting PhD student from Queen Mary University of London)
2020/11 - 2021/11 Inês Aires
2021/01 - 2021/04 Production and characterization of extracellular vesicles João Novo (MSc fellow)
2018/01/01 - 2021/03/31 Extracellular vesicles to treat brain ischemia Tiago Rondão (MSc fellow)
2020/07/01 - 2020/09/30 Functionalization of gold nanorods Natália Ferrari (Visiting MSc student)
2020/05/01 - 2020/09/30 Production of extracellular vesicles Clarissa Becher (MSc fellow)
2019/09/01 - 2020/03/31 Extracellular vesicles for the treatment of ischemic stroke Inês Morais (MSc fellow)
2020/01 - 2020/02 Cell culture; extracellular vesicle isolation and characterization Diana Pereira Gonçalves (Visiting undergraduate student)
2019/09/01 - 2019/10/01 Modification of extracellular vesicles with targeting peptides Francesco Catapano (visiting postdoctoral researcher)
2018/05/01 - 2018/05/31 Exosome isolation, characterization and modification strategies Luís Oliveira (MSc student)
Distinctions

Award

2023 Best poster - Joint Meeting of the ETRS & SPCE-TC, Coimbra, 2023
2023 Best poster - 2nd PNEV meeting, Lisbon, 2023
2022 Best poster award
Meeting on Biosystems in Toxicology and Pharmacology , Portugal
2017 Best Poster Prize
CESB, Portugal
2017 Best Poster Prize
Sociedade Portuguesa de Células Estaminais e Terapias Celulares, Portugal

Other distinction

2022 Short Term Scientific Mission
COST, European Cooperation in Science and Technology, Belgium
2021 Short term scientific mission
COST, European Cooperation in Science and Technology, Belgium
2021 FCT Scientific Employment Stimulus Awardee
Fundação para a Ciência e a Tecnologia, Portugal
2011 PhD scholarship (sfrh/bd/81705/2011)
Fundação para a Ciência e a Tecnologia, Portugal
2009 Travel grant - 7th International Stem Cell School in Regenerative Medicine
European Union Marie Curie Conferences and Training Courses, Belgium