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Flávio Reis holds a PhD in Biomedical Sciences (2006) from the Faculty of Medicine of the University of Coimbra (FMUC), where he is Principal Investigator and Leader of the Group "Therapeutics and nutraceuticals for chronic inflammatory disorders" at the Coimbra Institute for Clinical and Biomedical Research (iCBR). He is also group leader at the Center for Innovative Biomedicine and Biotechnology (CIBB), a UC biomedical research consortium formed by iCBR and Center for Neuroscience and Cell Biology (CNC). Flávio Reis is currently the coordinator of the Research Management Office at FMUC and held several other functions and positions, including in the UC General Council, UC Senate, in the FMUC Directive Council, in the Scientific Council of the Interdisciplinary Research Institute and in the Scientific Council of CIBB, both from UC. His scientific interests lie mainly in the field of therapeutic and nutraceutical interventions targeting cardiometabolic and renal diseases, including prediabetes, diabetes and its vascular complications (namely nephropathy), among other parallel interests. He has been working with animal models for more than 25 years and, considering the vast experience in this area, he is linked in various ways to Laboratory Animal Sciences (LAS). Actually, he: i) was president of the iCBR Animal Welfare Body (AWB) and is member of two other AWBs; ii) was chair of the organizing committee of the “3rd Nacional Symposium of AWBs: 3Rs in action”, held in Coimbra in 2018; iii) was the coordinator of the animal facility of iCBR; iv) is the coordinator of the Advanced Course on Animal Experimentation of the Doctoral Program in Health Sciences from FMUC; v) is member of the Executive Board of the Portuguese Society of Laboratory Animals Sciences (SPCAL) since 2021; vi) was chair of the organizing committee of the “5th SPCAL Congress: LAS for all”, held in Coimbra in 2024. Beyond preclinical research mainly involving animal models of disease, Flávio Reis has also been involved in multidisciplinary societal projects, developed in a perspective of co-creation with and for the community, involving different stakeholders, including patients, caregivers, entrepreneurs, among others. These projects aim to promote, integrate and support health literacy, namely toward healthy lifestyles. He coordinated and/or participated in about 60 projects, the majority of them with competitive funding and many supported by international agencies (EIT-Health, Erasmus Plus, Excellence Hubs, as examples), with a global amount for his Lab. work of more than 2 million euros. He was/is supervisor of about 130 students, including 4 postdocs, 20 PhD, 55 Master and 17 Degree, and participated in many PhD (47) and Masters (85) theses’ juris. He is (co)author of 175 full-papers published in international peer-reviewed journals, with more than 7,000 citations and an H index of 44, as well as editor of 2 international books and (co)author of 20 book chapters. He is also (co)author of other almost 220 publications (full-papers, proceedings and abstracts) published in international and national journals, as well as (co)author of more than 600 communications (as oral or poster presentation) in scientific meetings and was more than 30 times invited as speaker. He received 61 scientific merit awards. Flávio Reis is member of several national and international scientific societies and is President of the Portuguese Society of Pharmacology, was Vice-President of the Portuguese Society of Atherosclerosis and of the Portuguese Society of Hemorrheology and Microcirculation. He is a regular reviewer on evaluation panels for competitive funding in international research agencies (from UK, France, Italy, Switzerland, Austria and Chile), was reviewer of about 240 full-papers for more than 150 journals and is member of the Editorial Board of some. Flávio Reis is frequently involved in activities of dissemination and science communication to different target audiences
Identification

Personal identification

Full name
Flávio Nelson Fernandes Reis

Citation names

  • Reis, F

Author identifiers

Ciência ID
1C1D-1326-C311
ORCID iD
0000-0003-3401-9554

Email addresses

  • freis@fmed.uc.pt (Professional)

Addresses

  • Faculdade Medicina - Universidade de Coimbra. Sub-Unidade 1 - Polo 3 - Azinhaga de Santa Comba - Celas , 3000-548, Coimbra, Coimbra, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Advanced (C1) Intermediate (B1) Beginner (A1) Advanced (C1)
Education
Degree Classification
2021 - 2021
Concluded
Biomedical Sciences (Título de Agregado)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
Maximal classification by unanimity
2006
Concluded
Biomedical Sciences (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
"Vascular and platelet mechanisms in cyclosporin A-induced hypertension - Prevention using an NO donor - Isossorbide 5-Mononitrate" (THESIS/DISSERTATION)
Approved by Distinction and Honour by Unanimity (A
2000
Concluded
Cellular and Molecular Biology (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
"Cyclosporin A effects on platelet reactivity in an experimental animal model (Efeitos da ciclosporina A na reactividade plaquetar num modelo animal experimental)" (THESIS/DISSERTATION)
Excelent - unanimity (Muito Bom por Unanimidade)
1995
Concluded
Biochemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Affiliation

Science

Category
Host institution
Employer
2016/11/11 - Current Principal Investigator (Research) Universidade de Coimbra Faculdade de Medicina, Portugal
2010/09/14 - 2016/11/10 Auxiliary Researcher (Research) Universidade de Coimbra Faculdade de Medicina, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal

Teaching in Higher Education

Category
Host institution
Employer
2005/12/01 - 2010/09/13 Assistant (University Teacher) Universidade de Coimbra Faculdade de Medicina, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal

Other Careers

Category
Host institution
Employer
1998 - 2006 Técnico Superior (Técnico Superior) Universidade de Coimbra Faculdade de Medicina, Portugal

Positions / Appointments

Category
Host institution
Employer
2022/02/09 - Current Vice-President Sociedade Portuguesa de Farmacologia, Portugal
2021/04/01 - Current Member of Directive Board Sociedade Portuguesa de Ciências em Animais de Laboratório, Portugal
2020/01/01 - Current Member of the Scientific Council CIBB - Center for Innovative Biomedicine and Biotechnology, Portugal
2020 - Current Leader of the Group "Insulin resistance and diabetic angiopathy" at iCBR|FMUC and at CIBB Universidade de Coimbra Faculdade de Medicina, Portugal
2020 - Current Vice-President Sociedade Portuguesa de Hemorreologia e Microcirculação, Portugal
2016/01/02 - Current Coordinator of the Research Management Office - FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
2021 - 2023 Vice-President Sociedade Portuguesa de Aterosclerose, Portugal
2018/03/01 - 2020 President of the Animal Welfare Body (ORBEA) of iCBR/FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
2018/01/01 - 2020 Coordinator of the Animal Facility of iCBR/FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
2011/01/01 - 2018 Coordinator of the Laboratory of Animal Behavior and Research - ICBR/FMUC Universidade de Coimbra Faculdade de Medicina, Portugal

Others

Category
Host institution
Employer
2017/07/01 - Current Member (and Secretary) of the Assembly of FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
2013/01/01 - Current Member of Animal Welfare Body (ORBEA) of CNC/FMUC Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014/01/01 - 2020/01/27 Member of the Scientific Council - Institute of Interdisciplinary Research (UC) Institute of Interdisciplinary Research (Instituto Interdisciplinar de Investigação: 3Is-UC) University of Coimbra, Portugal
2018/01/01 - 2020 Member of the Coordination Group for the Preparation of the Strategic Planning of FMUC 2019/2024. Universidade de Coimbra Faculdade de Medicina, Portugal
2017/03/01 - 2018 Management Commission of Animal Facility of IBILI (now iCBR) - FMUC Instituto Biomédico de Investigação Luz e Imagem (IBILI) - Faculdade de Medicina de Coimbra, Portugal
2004 - 2015 Evaluation Council (SIADAP) for FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
2005 - 2007 Member of the Directive Council - FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
2005 - 2006 Member of Coimbra University Senade Universidade de Coimbra, Portugal
2004 - 2006 Member of the Assembly of Representatives - FMUC Universidade de Coimbra Faculdade de Medicina, Portugal
1996 - 1998 Monitor in a European Pharmacovigilance Research Group - Pancreatitis Study European Pharmacovigilance Research Group , United Kingdom
Projects

Grant

Designation Funders
2023/03/01 - 2025/02/28 Biomarkers for gadolinium renal injury
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade de Coimbra, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019 - 2020 INOV C 2020 – IGNITION GRANT - The therapeutic potential of senescent leaves of Vaccinium corymbosum L. (blueberry) in Multiple Sclerosis: enhancement of a regional agricultural by-product
SAAC - CENTRO-46-2016-01 - #5625
Principal investigator
Ongoing
2018 - 2019 Functional assessment of the immune system in the tumor microenvironment and at the peripheral level in patients with bladder cancer
Jaba Recordati 2018
Researcher
Concluded
2017 - 2018 Follow-up of patients undergoing laparoscopic gastric band surgery: Characterization of traditional and emerging lipid profile biomarkers
FULAGB/LPB_CESPU_2017
Researcher
CESPU - Cooperativa de Ensino Superior Politécnico e Universitário CRL
Concluded
2017 - 2018 Regulation of renal and extra-renal erythropoietin gene expression in anemia induced by chronic renal failure and by acute hypoxia
165
Researcher
Banco Santander Totta - FMUC
Concluded
2017 - 2018 Interaction between intestinal microbiota and metabolic dysregulation in prediabetes - Impact of blueberries as a nutraceutical intervention
Emílio Peres 2017
Principal investigator
Concluded
2016 - 2017 Association of dysfunction HDL with PCSK9 mutations and protein levels in myocardial infarction patients
167
Principal investigator
Banco Santander Totta - FMUC
Concluded
2016 - 2017 Unraveling biomarkers of early and asymptomatic cardiac and hepatic changes in prediabetes
GIFT 2016
Principal investigator
Concluded
2015 - 2016 Neuropeptide Y, Y1 receptor and dipeptidyl-peptidase 4: study of the interactions promoting remyelination in an animal model of multiple sclerosis
Biogen Idec Portugal
Principal investigator
Concluded
2014 - 2015 NK cell-based adoptive therapy targeting human bladder cancer stem cells: impact on tumor progression using an humanized orthotopic animal model
Uro-Oncology Grant 2013
Researcher
Astellas European Foundation, United Kingdom
Concluded
2013 - 2014 Natural Killer-cell based immunotherapy targeting human bladder cancer stem cells
GAI-FMUC-2013
Researcher
Concluded
2013 - 2013 Cytoprotective action of insulin on heart and hippocampus from type 1 versus type 2 diabetes animal models
Principal investigator
Sociedade Portuguesa de Diabetologia
Concluded
2012 - 2013 Strategies for ischemic conditioning in renal transplantation - usefulness in marginal grafts
Bolsa Astellas SPOT/APU 2012
Researcher
Sociedade Portuguesa de Transplantação / Associação Portuguesa de Urologia
Concluded
2012 - 2013 ROLE OF NK CELLS IN TUMORIGENESIS AND THERAPY RESPONSE OF BLADDER CANCER USING A HUMANIZED CSC-BASED ANIMAL MODEL
APU 2011
Researcher
Concluded
2012 - 2013 Role of NK Cells in tumorigenesis and therapy response of bladder cancer using a humanized CSC-based animal model
APU 2012
Associação Portuguesa de Urologia
2012 - 2012 Characterization of the early cardiometabolic risk of patients with multiple sclerosis and of patients with systemic lupus erythematosus - correlation with staging, therapeutics and lifestyle habits
Bolsa Esperança, Vida e Solidariedade Merck Serono
Grupo de Estudos de Esclerose Múltipla | Merck Serono
2012 - 2012 Characterization of the early cardiometabolic risk of patients with multiple sclerosis and of patients with systemic lupus erythematosus - correlation with staging, therapeutics and lifestyle habits
Bolsa “Esperança, Vida e Solidariedade – Merck Serono
Grupo de Estudos de Esclerose Múltipla | Merck Serono
2012 - 2012 Characterization of the early cardiometabolic risk of patients with multiple sclerosis and of patients with systemic lupus erythematosus - correlation with staging, therapeutics and lifestyle habits
Bolsa “Esperança, Vida e Solidariedade – Merck Serono
Grupo de Estudos de Esclerose Múltipla | Merck Serono
2012 - 2012 Characterization of the early cardiometabolic risk of patients with multiple sclerosis and of patients with systemic lupus erythematosus - correlation with staging, therapeutics and lifestyle habits
Bolsa “Esperança, Vida e Solidariedade – Merck Serono
Grupo de Estudos de Esclerose Múltipla | Merck Serono
2009 - 2010 Bladder tumors - cytogenetic characterization and pharmacological investigation in cell cultures
Jaba Recordati 2009
Researcher
Associação Portuguesa de Urologia | Jaba Recordati
Concluded
2008 - 2009 Bladder tumors - clinical study of prognostic factors and prevention and experimental pharmacological treatment
APU 2018
Researcher
Concluded
2008 - 2009 Bladder tumors - clinical study of prognostic factors and prevention and experimental pharmacological treatment
APU 2008
Associação Portuguesa de Urologia
2007 - 2008 Study of the effectiveness of gliptins in prevention of pancreatic injury in an experimental model of diabetes mellitus type 2 - ZDF rat
Merk Sharp & Dohme
Researcher
Concluded
2004 - 2005 Experimental model of bladder carcinoma and evaluation of pharmacological efficacy preventive and curative
APU | JABA 2004
Researcher
Associação Portuguesa de Urologia - Jaba Recordati
Concluded

Contract

Designation Funders
2022/01/01 - Current CoLab HEALTHYAGEING@LAB
HEALTHYAGEING@LAB
Researcher
Universidade de Coimbra, Portugal
FCT - Fundação para a Ciência e Teconologia | COMPETE
Ongoing
2018/07 - Current DIAL4LIFE - Dialysis membranes by design: targeting neutrophil elastase to reduce inflammation/oxidative stress in end-stage renal disease
PT2020-SAICT-PTDC/ICDT-031322
PTDC/MEC-CAR/31322/2017
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07 - Current PHENOLIVA - Contribution of olive and olive oil polyphenolic compounds to the prevention of cardiovascular diseases.
PT2020-SAICT-PTDC/ICDT-032492
POCI-01-0145-FEDER-032492
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07 - Current CAPEOSBAC - Tailored microenCAPsulation technology for Extreme Oxygen-Sensitive BACteria with beneficial effects on gut microbiota: Production, stability and functionality enhancements in various carriers
PT2020-SAICT-PTDC/ICDT-031400
PTDC/BAA-AGR/31400/2017
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07 - Current FRUITIFY - Use of blueberry juice as a nutraceutical strategy targeting gut dysbiosis to prevent the progression from prediabetes to diabetes.
POCI-01-0145-FEDER-031712
Principal investigator
Fundação para a Ciência e a Tecnologia
Ongoing
2023 - 2028 PAS GRAS - De-risking metabolic, environmental and behavioral determinants of obesity in children, adolescents and young adults
101080329
Researcher
Universidade de Coimbra, Portugal
Horizon Europe
Ongoing
2023 - 2026 CHAngeing - Connected Hubs in Ageing: Healthy Living to Protect Cerebrovascular Function
101087071
Researcher
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
Horizon Europe Excellent Science
Ongoing
2023 - 2026 PRR - Cogumelos do Prado ao Prato: do tratamento de doenças do metabolismo a dieta saudável sustentável a partir da valorização de recursos agro-florestais
PRR-C05-i03-I-000160
Researcher
Universidade de Coimbra, Portugal
European Union
Ongoing
2021/01/01 - 2025/12/31 Centro de Inovação em Biomedicina e Biotecnologia - Laboratório Associado
LA/P/0058/2020
Universidade de Coimbra, Portugal

Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/01/01 - 2024 LOLit - Low Literacy at Play
2021-1-NL01-KA220-ADU-000033664
Principal investigator
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
Erasmus Plus
Ongoing
2023 - 2024 HIVE - HEI Innovation for Knowledge Intensive Entrepreneurship
220818
Researcher
Universidade de Coimbra, Portugal
EIT Health
Ongoing
2023 - 2024 GadoNephroRisk - Biomarcadores de lesão renal induzida pelo gadolínio
2022.08400.PTDC
Researcher
Universidade do Porto, Portugal
FCT - Fundação para a Ciência e Tecnologia
Ongoing
2022 - 2023 MitoBOOST 2.0 – A proof of concept for the use of mitochondria-targeted polyphenols to treat non-alcoholic fatty liver disease
CENTRO-01-0145-FEDER-181226
Researcher
Universidade de Coimbra, Portugal
FCT and European Regional Development Fund (ERDF)
Concluded
2020 - 2023 ALCHEMY – Capturing high value from industrial fermentation bioproduts
POCI-01-0247-FEDER-02757
Researcher
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
FCT and European Regional Development Fund (ERDF)
Concluded
2018/07/07 - 2022/07/06 Contribuição dos polifenóis da oliveira e do azeite para a prevenção das doenças cardiovasculares.
PTDC/OCE-ETA/32492/2017
Universidade de Coimbra, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2021/01/01 - 2022 Healthy Loneliness
1653337
Researcher
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
Erasmus Plus
Concluded
2021/01/01 - 2021/12/31 GluVac-COVID19 – Explorar o potencial de ß-glucanas como adjuvantes imunológicos no desenvolvimento de vacinas para a Covid-19
59949
Researcher
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
FCT - Fundação para a Ciência e Teconologia | COMPETE
Concluded
2020/05 - 2021/10 Tailored microenCAPsulation technology for Extreme Oxygen-Sensitive BACteria with beneficial effects in the gut microbiota: Production, stability and functionality enhancements in various carriers
PTDC/BAA-AGR/31400/2017
Universidade Católica Portuguesa, Portugal

Universidade de Coimbra, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/06/01 - 2021/05/31 CapEosBac: Tailored microencapsulation technology for beneficial gut extreme oxygen-sensitive bacteria: production, stability and functionality enhancements.
PTDC/BAA-AGR/31400/2017
Universidade Católica Portuguesa, Portugal

Universidade de Coimbra, Portugal

Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/06/01 - 2021/05/31 Use of blueberry juice as a nutraceutical strategy aimed at intestinal dysbiosis to prevent the evolution of pre-diabetes to diabetes
PTDC/SAU-NUT/31712/2017
Universidade Católica Portuguesa, Portugal

Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2017 - 2021 HEALTHY AGING 2020
CENTRO-01-0145-FEDER-000012
Researcher
FCT and European Regional Development Fund (ERDF)
Ongoing
2020/01/01 - 2020/12/31 Solidão no idoso e pandemia de Covid-19
20515
Researcher
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
European Institute of Innovation & Technology (EIT) - HEALTH
Concluded
2017 - 2020 MOBFOOD - Mobilization of scientific and technological knowledge in response to the challenges of the agrifood market
POCI-01-0247-FEDER-024524
Researcher
ERDF - European Regional Development Fund
Ongoing
2017 - 2020 NephroCardio Risk - Reliable biomarkers of chronic kidney disease and of the associated cardiovascular risk. Construction of (bio)sensors for the selected biomarkers
Norte-01-0145-FEDER-000024
Researcher
Ongoing
2019/01/01 - 2019/12/31 CRISH 2 – Co-cReating Innovative Solutions for Health 2.0
18053
Researcher
European Institute of Innovation & Technology (EIT) - HEALTH, Germany
Concluded
2019/01/01 - 2019/12/31 HEALIQS 4 CITIES – Healthy Lifestyle Innovation Quarters for Cities and Citizens (2019)
19142
Researcher
European Institute of Innovation & Technology (EIT) - HEALTH, Germany
Concluded
2019/01/01 - 2019/12/31 Engage Local Players 2019 - EIT RIS (Regional Innovation Scheme)
19513
Researcher
European Institute of Innovation & Technology (EIT) - HEALTH, Germany
Concluded
2016/04/01 - 2019/04/01 Targeting p53 family proteins: on the route to new anticancer agents
PTDC/DTP-FTO/1981/2014
Universidade do Minho, Portugal

Universidade de Coimbra, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/01 - 2018/12 Healthy Lifestyle Innovation Quarters for Cities and Citizens - 2018
18036
EIT Health
2016 - 2018 Targeting p53 family proteins: on the route to new anticancer agentes
PTDC/DTP-FTO/1981/2014
Researcher
FCT - Fundação para a Ciência e Tecnologia
Concluded
2013 - 2015 NANODAIRY - NANOparticles as Delivery systems of bioactive polyphenolic compounds to DAIRY matrices: evaluation of stability, bioavailability and toxicity
PTDC/AGR-ALI/117808/2010
Researcher
FCT - Fundação para a Ciência e Teconologia | COMPETE
Concluded
2012 - 2015 Cross-talk between chronic renal failure, inflammation and erythropoiesis in resistance to recombinant human erythropoietin therapy
PTDC/SAU-TOX/114253/2009
Principal investigator
FCT - Fundação para a Ciência e Tecnologia
Concluded
2012 - 2013 Regulation of erythropoietin gene expression in non-renal tissues
REISF2
Principal investigator
FMUC - Faculdade de Medicina da Universidade de Coimbra
Concluded
2012 - 2013 Drug-induced cardiorenal toxicity post-kidney transplantation - biomolecular bases for the choice of protocols of early or late CsA to SRL conversion and of better anti-hypertensive/renoprotective therapeutics
REISF1
Principal investigator
FMUC - Faculdade de Medicina da Universidade de Coimbra
Concluded
2012 - 2013 DPP-IV inhibitors and GLP-1 as potential therapeutic options for the treatment of diabetic retinopathy: novel insights into the mechanisms of action
EFSD-GSK-2012
Researcher
European Foundation for the Study of Diabetes, Germany
Concluded
2011 - 2013 From molecules to man: novel diagnostic imaging tools in neurological and psychiatric disorders
Projeto Centro-07-ST24-FEDER-002005
Researcher
FEDER - Programa Regional do Centro - QREN
Concluded
2011/01/01 - 2012/12/31 Projecto Estratégico - LA 2 - 2011-2012
PEst-C/SAU/LA0002/2011
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2012/12/31 Projecto Estratégico - UI 3282 - 2011-2012
PEst-C/SAU/UI3282/2011
Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2008 - 2010 Risk for cardiovascular events in chronic kidney disease patients under haemodialysis. Lipid profile, anemia, vascular access and inflammation
PIC/IC/83221/2007
Researcher
FCT - Fundação para a Ciência e Tecnologia
Concluded
2007 - 2010 Mechanisms of resistance to recombinant human erythropoietin in patients with chronic renal failure and hemodialysis
PTDC/SAU-FCF/64815/2006
Researcher
FCT - Fundação para a Ciência e Tecnologia
Concluded
2005 - 2007 Prognostic value of inflammatory and oxidative stress markers in psoriasis
POCI/SAU-OBS/58600/2004
Researcher
FCT - Fundação para a Ciência e Tecnologia
Concluded
1998 - 2000 Cyclosporin effects in smooth muscle stimulation and proliferation: propose of preventive drugs
PRAXIS/PSAU/C/SAU/57/96
Researcher
FCT - Fundação para a Ciência e Tecnologia
Concluded
1996 - 1998 Drug-induced acute pancreatitis - European Pharmacological Research Group
BIOMED 2 project (BMH4-CT95-0467)
Research Technician Fellow
European Community - BIOMED 2
Concluded
Outputs

Publications

Book
  1. Palavra, F.; Reis, F.; Marado, D.; Sena, A.. Preface. 2015.
  2. Teixeira-Lemos, E.; Teixeira, H.M.; Piloto, N.; Teixeira, M.; Parada, B.; Rodrigues-Santos, P.; Carvalho, L.; et al. Cardiometabolic injury due to recombinant human erythropoietin doping for improvement of sports performance: Chronic (training) versus acute (extenuating) aerobic exercise. 2012.
  3. Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Figueiredo, A.; Teixeira, F.; Castro, E.; Rocha-Pereira, P.; Santos-Silva, A.. Psoriasis Comorbidities and the Incidence of Risk Factors for Cardiovascular Disease Events in Psoriasis. 2011.
  4. Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Figueiredo, A.; Teixeira, F.; Castro, E.; Rocha-Pereira, P.; Santos-Silva, A.. Psoriasis comorbidities and the incidence of risk factors for cardiovascular disease events in psoriasis. 2011.
Book chapter
  1. Flávio Reis. "Microbiota intestinal (Cap. 4)". In Manual de lípidos. Portugal: Cultura Editora, 2021.
    Published
  2. Reis, Flávio. "TUBEROUS SCLEROSIS COMPLEX (Chapter 99)". In Handbook of Tumor Syndromes. Taylor and Francis CRC Press, 2020.
    In press
  3. Santos-Silva A; Ribeiro S; Reis F; Belo L. "Hepcidin in chronic kidney disease anemia (Chapter 12)". In Vitamins and hormones. Elsevier Inc., 2019.
    Published • 10.1016/bs.vh.2019.01.012
  4. Reis, Flávio. "O RIM COMO ÓRGÃO-ALVO DA TOXICIDADE DE XENOBIÓTICOS (Capítulo 6)". In Toxicologia Fundamental. Lidel, 2018.
    Published
  5. Patel, Bhoomika M.. "DIABETIC CARDIOMYOPATHY: FOCUS ON OXIDATIVE STRESS, MITOCHONDRIAL DYSFUNCTION AND INFLAMMATION (Chapter 12)". In Cardiomyopathies - Types and Treatments, 413-425. InTech, 2017.
    Published • 10.1007/978-981-13-8273-4_18
  6. Reis, Flávio. "THE HIF SYSTEM RESPONSE TO ESA THERAPY IN CKD-ANEMIA (Chapter 14)". In Hypoxia and Human Diseases. InTech, 2017.
    Published
  7. Reis, Flávio. "DIABETIC CARDIOMYOPATHY: FOCUS ON OXIDATIVE STRESS, MITOCHONDRIAL DYSFUNCTION AND INFLAMMATION (Chapter 12) - Authors: Sara Nunes, Anabela Pinto Rolo, Carlos Manuel Palmeira and Flávio Reis". 2017.
  8. Reis, Flávio. "mTOR and Neuroinflammation (Chapter 19)". In Molecules to Medicine with mTOR, 317-329. Elsevier, 2016.
    Published • 10.1016/B978-0-12-802733-2.00002-5
  9. Reis, Flávio. "mTOR in Diabetic Nephropathy and Retinopathy (Chapter 23)". In Molecules to Medicine with mTOR, 379-393. Elsevier, 2016.
    Published • 10.1016/B978-0-12-802733-2.00001-3
  10. Reis, Flávio. "INFLAMMATION BIOMARKERS AND CARDIOMETABOLIC RISK (Chapter 1)". In Biomarkers of Cardiometabolic Risk, Inflammation and Disease, 1-24. Springer International Publishing, 2015.
    Published • 10.1007/978-3-319-16018-4_1
  11. Reis, Flávio. "CARDIOVASCULAR DISEASE (Chapter 2)". In Biomarkers of Cardiometabolic Risk, Inflammation and Disease. Springer International Publishing, 2015.
    Published • 10.1007/978-3-319-16018-4_2
  12. Fernandes, A; Providência, R; Reis, F; Gonçalves, Lino. "Cardiovascular Diseases". In Biomarkers of Cardiometabolic Risk, Inflammation and Disease. Springer, 2015.
  13. Reis, Flávio. "RHEPO FOR THE TREATMENT OF ERYTHROPOIETIN RESISTANT ANEMIA IN HEMODIALYSIS PATIENTS – RISKS AND BENEFITS (Chapter 16)". In Hemodialysis. InTech, 2013.
    Published • 10.5772/52061
  14. Reis, Flávio. "REGULATION OF ERYTHROPOIETIN GENE EXPRESSION (Chapter 2)". In Frontiers in Drug Discovery: Erythropoietic Stimulating Agents. BENTHAM SCIENCE PUBLISHERS, 2013.
    Published
  15. Reis, Flávio. "ANIMAL MODELS OF KIDNEY DISEASE-ASSOCIATED ANEMIA (Chapter 4)". In Frontiers in Drug Discovery: Erythropoietic Stimulating Agents. BENTHAM SCIENCE PUBLISHERS, 2013.
    Published
  16. Reis, Flávio. "RISKS AND BENEFITS ASSOCIATED WITH HIGH THERAPEUTIC DOSES OF ERYTHROPOIESIS STIMULATING AGENTS (Chapter 5)". In Frontiers in Drug Discovery: Erythropoietic Stimulating Agents. BENTHAM SCIENCE PUBLISHERS, 2013.
    Published
  17. Ribeiro, S; Costa, E; Belo, L; Reis, F; Santos-Silva, A. "rhEPO for the Treatment of Erythropoietin Resistant Anemia in Hemodialysis Patients – Risks and Benefits". In Hemodialysis, 291-314. Croatia: InTech, 2013.
    Published
  18. Garrido, P; Costa, E; Reis, F; Santos-Silva, A. "Animal Models of Kidney Disease-Associated Anemia". In Frontiers in Drug Discovery: Erythropoietic Stimulating Agents, 61-80. U.A.E.: Bentham Science Publisher, 2013.
    Published
  19. Ribeiro, S; Costa, E; Reis, F; Santos-Silva, A. "Risks and Benefits Associated with High Therapeutic Doses of Erythropoiesis Stimulating Agents". In Frontiers in Drug Discovery: Erythropoietic Stimulating Agents, 81-97. U.A.E.: Bentham Science Publisher, 2013.
    Published • 10.2174/9781608057474113010008
  20. Reis, Flávio. "PHYSICAL ACTIVITY AND INFLAMMATION – AN OVERVIEW (Chapter 21)". In Chronic inflammation: molecular pathophysiology, nutritional and therapeutic interventions. CRC Press, 2012.
    Published
  21. Reis, Flávio. "CANNABINOIDS: FORENSIC TOXICOLOGY AND THERAPEUTICS (Chapter 10)". In Forensic Medicine - From Old Problems to New Challenges. InTech, 2011.
    Published
  22. Reis, Flávio. "PSORIASIS COMORBIDITIES AND THE INCIDENCE OF RISK FACTORS FOR CARDIOVASCULAR DISEASE EVENTS IN PSORIASIS (Chapter 5)". In Psoriasis: causes, diagnosis and treatment. Nova Science Publishers, 2011.
    Published
  23. Reis, Flávio. "CARDIOMETABOLIC INJURY DUE TO RECOMBINANT HUMAN ERYTHROPOIETIN DOPING FOR IMPROVEMENT OF SPORTS PERFORMANCE (Chapter 4)". In Athlete Performance and Injuries. Nova Science Publishers, 2011.
    Published
  24. Teixeira de Lemos, E; Teixeira, HM; Piloto, N; Teixeira, M; Parada, B; Santos, P; Carvalho, L; et al. "Cardiometabolic Injure due to Recombinant Human Erythropoietin Doping for Improvement of Sports Performance – Chronic (Training) versus Acute (Extenuating) Aerobic Exercise". In Performance and Injuries, 0-0. NY: Nova Science Publishers, 2011.
    Published
  25. Piloto, N; Teixeira, HM; Teixeira de Lemos, E; Parada, B; Garrido, P; Sereno, J; Ferreira, I; et al. "Toxicological effects of recombinant human erythropoietin doping - chonic versus acute aerobic exercice". In Acta Medicinae Legalis et Socialis, 275-282. Coimbra: Imprensa da Universidade de Coimbra - International Academy of Legal Medicine, 2010.
    Published
  26. Piloto, N; Teixeira, HM; Teixeira de Lemos, E; Parada, B; Garrido, P; Sereno, J; Pinto, AF; et al. "Erythropoietin doping as cause of sudden death in athletes - an experimental study". In Acta Medicinae Legalis et Socialis, 267-273. Coimbra: Imprensa da Universidade de Coimbra - International Academy of Legal Medicine, 2010.
    Published
Conference abstract
  1. Nunes, S; Viana, S; Preguiça, I; Alves, A; Fernandes, R; Jarak, I; Carvalho, R; et al. "Unraveling the hepatoprotective effects of blueberries in a hypercaloric diet-induced rat model of prediabetes by metabolomic and transcriptomic approaches". Paper presented in AnnualMeeting 2021 Coimbra Heath School - Global Health: New Trends, 2021.
    10.1093/eurpub/ckab120.106
  2. Alves, A; Preguiça, I; Barbosa, A; Vieira, P; Martins, D; Nunes, S; Viana, S; Reis, F. "Blueberries effects in experimental diet-induced prediabetes: a focus on renal impairment, European Journal of Public Health, Volume 30, Issue Supplement_2, June 2020". 2020.
    Published • 10.1093/eurpub/ckaa040.055
  3. Nunes, Sara; Viana, SD; Rolo, Anabela Pinto; Palmeira, Carlos; André, MA; Cavadas, Claudia; Pintado, Maria Manuela; Reis, Flávio. "Effects of blueberry juice intake on liver injury progression in a hypercaloric diet-induced prediabetic rat model". Paper presented in 12th MiP/MitoEAGLE Training School 2019; University of Coimbra, Coimbra, 2019.
    Published
  4. Nunes, S; Viana, S; Rolo, A; Palmeira, C; André, A; Cavadas, C; Pintado, M; Reis, F. "Blueberry juice as a nutraceutical approach to prevent prediabetes progression in an animal model: focus on hepatic steatosis". Paper presented in Annual meeting ESTeSC 2019. “Primary health care: Challenges and Oportunities", Coimbra, 2019.
    10.1093/eurpub/ckz034.011
  5. Nunes, Sara; Viana, SD; Castela, Ana; Rolo, Anabela Pinto; Palmeira, Carlos; André, MA; Cavadas, Claudia; Pintado, MM; Reis, Flávio. "Blueberry juice attenuates liver injury progression in a rat model of diet-induced prediabetes.". Paper presented in 1st Meeting in Translational Pharmacology, 38th Spanish Society of Pharmacology meeting/9th Spanish Society of Pharmacogenetics and Pharmacogenomics meeting; 19–20 June 2018,, Santiago de Compostela, 2018.
    Published • 10.1111/bcpt.13084
  6. Coimbra, Susana; Reis, Flávio; Nunes, Sara; Viana, Sofia D.; Rocha, Susana; Santos-Silva., Alice. "Atherogenic properties of ldl particles in ESRD patients on hemodialysis.". Paper presented in 55th ERA-EDTA congress, May 24-27, 2018; Copenhagen, 2018.
    Published
  7. alves, MP; Boia, Raquel; Campos, Elisa J.; Martins, João; Nunes, Sara; madeira, mh; Reis, Flávio; et al. "Early retinal changes in a rat model of prediabetes: assessment of blood-retinal barrier permeability, neural markers and inflammatory mediators". Paper presented in 7th Annual Meeting of IBILI, Coimbra, 2015.
    Published
  8. Ribeiro, Sandra; Nunes, Sara; Garripo, Patricia; Fernandes, João; Rocha, S; Reis, Flávio; Santos-Silva, Alice. "Liver iron regulates hepcidin expression. Studies in a rat model of chronic renal failure under recombinant human erythropoietin therapy". Paper presented in 40th Congress of the Federation-Of-EuropeanBiochemical-Societies (Febs), 2015.
    Published
  9. Ribeiro, S; Fernandes, J; Garrido, P; Sereno, J; Vala, H; Bronze-da-Rocha, E; Belo, L; et al. "RhuEPO induced-hypertension leads to early renal damage". Paper presented in ERA-EDTA 51st congress, Amesterdão, 2014.
    Published • 10.1093/ndt/gfu142
  10. Garrido, P; Fernandes, J; Ribeiro, S; Belo, L; Costa, E; Reis, F; Santos-Silva, A. "THE CRUCIAL ROLE OF IRON METABOLISM IN ERYHTROID HYPOPLASIA/PURE RED CELL APLASIA DUE TO THE DEVELOPMENT OF ANTI-EPO ANTIBODIES". Paper presented in ERA-EDTA 51st congress, Amesterdão, 2014.
    Published • 10.1093/ndt/gfu162
  11. Fernandes, J; Ribeiro, S; Garrido, P; Sereno, J; Costa, E; Reis, F; Santos-Silva, A. "TRANSCRIPTOR FACTORS RESPONSIBLE FOR EPO GENE REGULATION, TRIGGERED BY ADMINISTRATION OF RHUEPO HIGH DOSES". Paper presented in ERA-EDTA 51st congress, Amesterdão, 2014.
    Published
  12. Catarino, C; Cunha, P; Ribeiro, S; Rocha-Pereira, P; Reis, F; Sameiro-Faria, M; Miranda, V; et al. "STWEAK AND PTX3 AS MARKERS OF ENDOTHELIAL (DYS)FUNCTION AND INFLAMMATION IN END-STAGE RENAL DISEASE PATIENTS UNDER HEMODIALYSIS". Paper presented in ERA-EDTA 51st congress, Amesterdão, 2014.
    Published
  13. Fernandes, J; Ribeiro, S; Garrido, P; Sereno, J; Costa, E; Reis, F; Santos-Silva, A. "REGULATION OF LIVER AND KIDNEY ERYTHROPOIETIN GENE EXPRESSION IN A RAT MODEL OF ANEMIA ASSOCIATED WITH CHRONIC RENAL FAILURE". Paper presented in ERA-EDTA 51st congress, Amesterdao, 2014.
    Published • 10.1093/ndt/gfu147
  14. Garrido, P; Fernandes, J; Ribeiro, S; Vala, H; Belo, L; Costa, E; Santos-Silva, A; Reis, F. "HISTOLOGICAL KIDNEY CHANGES ASSOCIATED WITH LOW AND HIGH RECOMBINANT HUMAN ERYTHROPOIETIN DOSES IN A RAT MODEL OF CHRONIC KIDNEY DISEASE". Paper presented in ERA-EDTA 51st congress, Amesterdão, 2014.
    Published
  15. Kohlova, M; Ribeiro, S; do Sameiro Faria, M; Rocha Pereira, P; Fernandes, J; Reis, F; Miranda, V; et al. "HEMODIALYSIS TO ONLINE-HEMODIAFILTRATION CHANGE IS ASSOCIATED TO A DECREASE IN CIRCULATING CELL-FREE DNA LEVELS". 2013.
  16. Garrido, P; Fernandes, J; Ribeiro, S; Vala, H; Parada, B; Alves, R; Belo, L; et al. "THE 5/6 NEPHRECTOMIZED RAT AS A GOOD MODEL TO STUDY CHRONIC KIDNEY DISEASE". 2013.
  17. Ribeiro, S; Follador, B; Nascimento, H; Fernandes, J; Garrido, P; Vala, H; Sereno, J; et al. "Aging is associated with a decreased in renal function and in iron availability, and with an increased in inflammation status". Paper presented in Encontro Renal 2013, Vila Moura, 2013.
    Published
  18. Ribeiro, S; Kohlova, M; Srbová, L; Fernandes, J; Rocha, S; Borges, M; Reis, F; et al. "Erythrocyte haemolysis and lymphocyte apoptosis: effect of urea and recombinant human erythropoietin". Paper presented in Encontro Renal 2013, Vila Moura, 2013.
    Published
  19. Ribeiro, S; Costa, E; Sameiro-Faria, M; Rocha-Pereira, P; Kohlova, M; Fernandes, J; Reis, F; et al. "Cross-talk between circulating cell-free DNA levels, inflammation, iron metabolism disturbances and rhEPO doses in hemodialysis patients". Paper presented in Encontro Renal 2013, Vila Moura, 2013.
    Published
  20. Ribeiro, S; Sameiro-Faria, M; Rodrigues, S; Nascimento, H; Fernandes, J; Rocha, S; Rocha-Pereira, P; et al. "On-line hemodiafiltration is associated with improved dialysis adequacy, iron availability, lipidic profile and nutritional statu". Paper presented in Encontro Renal 2013, Vila Moura, 2013.
    Published
  21. Ribeiro, S; Kohlova, M; Sameiro-Faria, M; Rocha-Pereira, P; Fernandes, J; Nascimento, H; Reis, F; et al. "Bilirubin levels are associated with beneficial effects in patients under hemodialysis". Paper presented in Encontro Renal 2013, Vila Moura, 2013.
    Published
  22. Reis, F; Garrido, P; Fernandes, J; Ribeiro, S; Vala, H; Alves, R; Parada, B; et al. "Resistance to rhepo therapy due to production of anti-Epo antibodies in a rat model of chronic renal failure". Paper presented in Encontro Renal 2013, Vila Moura, 2013.
    Published
  23. Vala, H; Garrido, P; Ribeiro, S; Fernandes, J; Prada, B; Alves, R; Belo, L; et al. "The 5/6 nephrectomized rat as a good model for the study of anaemia associated with functional and structural kidney damage". 2013.
  24. Vala, H; Garrido, P; Ribeiro, S; Fernandes, J; Parada, B; Alves, R; Belo, L; et al. "Histological kidney changes associated with high rhEPO doses in a rat model of chronic renal failure". 2013.
  25. Garrido, P; Teixeira, M; Costa, E; Rodrigues Santos, P; Parada, B; Belo, L; Alves, R; et al. "EARLY RECOMBINANT HUMAN ERYTHROPOIETIN TREATMENT PROMOTES CARDIORENAL CYTOPROTECTION IN A RAT MODEL OF CHRONIC RENAL FAILURE". 2012.
  26. Sameiro-Faria, M; Ribeiro, S; Costa, E; Mendonça, D; Teixeira, L; Rocha-Pereira, P; Fernandes, J; et al. "Factores de risco cardiovasculares em doentes renais crónicos em hemodiálise. Perfil lipidico, anemia e resistencia à rhEPO - "follow-up" de dois anos". Paper presented in X Congresso de Análises Clínicas e Saúde Pública, Porto, 2012.
    Published
  27. Garrido, Patrícia; Fernandes, J; Costa, E; Ribeiro, S; Sereno, J; Mascarenhas-Melo, Filipa; Parada, B; et al. "Erythropoietic response to rhEPO therapy is dependent on the stage of renal failure ¿ an experimental study in nephrectomized rats". Paper presented in Encontro Renal 2012, Vilamoura, 2012.
    Published
  28. Sameiro-Faria, M; Costa, E; Rocha-Pereira, P; Borges, A; Mendona, D; Amado, L; Reis, F; et al. "Predictive factors for mortality in portuguese hemodialysis patients: a prospective 12 months follow-up study". Paper presented in 25º Congresso da Sociedade Portuguesa de nefrologia, Vila Moura, 2011.
    Published
  29. Sereno, J; Romão, AM; Parada, B; Garrido, P; Alves, R; Costa, E; Santos-Silva, A; Teixeira, F; Reis, F. "Early versus late cyclosporin to sirolimus conversion in an animal model: focus on cardiorenal benefits". Paper presented in 25º Congresso da Sociedade Portuguesa de Nefrologia, Vila Moura, 2011.
    Published
  30. Costa, E; Pereira, R; Rocha, S; Borges, A; Nascimento, H; Reis, F; Miranda, V; et al. "Elastase release during haemodilysis procedure seem to induce changes in red blood cells membrane proteins". Paper presented in 25º Congresso da Sociedade Portuguesa de Nefrologia, Vila Moura, 2011.
    Published
  31. Garrido, P; Teixeira, M; Costa, E; Rodrigues-Santos, P; Parada, B; Alves, R; Teixeira, F; Santos-Silva, A; Reis, F. "Anti-apoptotic and pro-proliferative action of early erythropoietin therapy in an animal model of moderate chronic renal failure". Paper presented in 25º Congresso da Sociedade Portuguesa de Nefrologia, Vila Moura, 2011.
    Published
  32. Sameiro-Faria, M; Costa, E; Rocha-Pereira, P; Borges, A; Nascimento, H; Mendonça, D; Amado, L; et al. "Inflammation, erythropoietic disturbances and the type of vascular access are the principal risk factors for mortality in haemodialysis patients". Paper presented in XLVIII ERA-EDTA Congress 2011, Praga, 2011.
    Published
  33. Pereira, R; Rocha, S; Borges, A; Nascimento, H; Reis, F; Miranda, V; Sameiro-Faria, M; et al. "The effect of elastase upon membrane proteins of red cells from haemodialysis patients under rhEPO therapy". Paper presented in VIII Congresso de Análises Clínicas e Saúde Pública da sociedade Portuguesa de Bioanalistas Clínicos, Coimbra, 2010.
    Published
  34. Coimbra, S; Oliveira, H; Reis, F; Belo, L; Rocha, S; Figueiredo, A; Teixeira, F; et al. "Evaluation of erythrocyte changes in Portuguese psoriatic patients - relation with treatment". 2010.
  35. Parada, Belmiro Ataíde da Costa; Figueiredo, A.; Reis, F; Nunes, P; Sereno, J; Eufrasio, P.; Garrido, P.; Xavier-Cunha, Maria; Mota, A.. "Antitumoral Properties of a Cyclooxigenase-2 Inhibitor and Immunosuppression Agents on Rat Urinary Bladder Carcinogenesis". Paper presented in Congres de la Société Internationale de Urologie, Shangai, China, 2009.
    Published • 10.1016/j.urology.2009.07.874
  36. Elisio, C; Rocha, S; Rocha Pereira, P; Castro, E; Reis, F; Teixeira, F; Miranda, V; et al. "CROSS-TALK BETWEEN INFLAMMATION AND IRON STATUS, AND ITS ASSOCIATION WITH RESISTANCE TO RECOMBINANT HUMAN ERYTHROPOIETIN THERAPY IN HAEMODIALYSIS PATIENTS". 2009.
  37. Teixeira de Lemos, ET; Reis, F; Baptista, S; Pinto, R; Sepodes, B; Vala, H; Rocha Pereira, PR; Santos Silva, AS; Teixeira, F. "PHYSICAL ACTIVITY AS ANTI-INFLAMMATORY THERAPY IN AN ANIMAL MODEL OF TYPE 2 DIABETES". 2008.
    10.1016/s1567-5688(08)70398-2
  38. Moreiras, A; Coimbra, S; Rocha Pereira, P; Oliveira, H; Belo, L; Reis, F; Figueiredo, A; et al. "Cytogenotoxicity of therapeutic models used in psoriasis vulgaris". 2007.
  39. Coimbra, S; Castro, E; Rocha Pereira, P; Oliveira, H; Belo, L; Reis, F; Rocha, S; et al. "C-reactive protein in mild to severe psoriasis vulgaris". 2007.
  40. Teixeira, F; de Lemos, ET; Reis, F; Baptista, S; Pinto, R; Sepodes, B; Vala, H; Rocha Pereira, P; Santos Silva, A. "Exercise training and the inflammatory response in ZDF (type 2) diabetic rats". 2007.
    10.1016/s1567-5688(07)71253-9
  41. Coimbra, S; Castro, E; Rocha Pereira, P; Oliveira, H; Belo, L; Reis, F; Rocha, S; et al. "Neutrophil activation associated to psoriasis vulgaris severity". 2007.
Conference paper
  1. Belo, Luís Filipe Barbosa Amado; Coimbra, Susana; Rocha, Susana; D. Viana, Sofia; Rebelo, Rute; Petronila Rocha-Pereira; Valente, Maria João; et al. Corresponding author: Santos-Silva, Alice. "Gadolinium and gadoteric acid's short-term impact on kidney function and lipid profile". Paper presented in Gadolinium and gadoteric acid's short-term impact on kidney function and lipid profile, Stockholm, 2024.
    Accepted
  2. Coimbra, Susana; Rocha, Susana; D. Viana, Sofia; Rebelo, Rute; Valente, Maria João; Petronila Rocha-Pereira; Catarino, Cristina; et al. Corresponding author: Santos-Silva, Alice. "Short-term effects of gadolinium and gadoteric acid on kidney – impact on inflammation". Paper presented in 61st ERA-EDTA Congress, Stockholm, 2024.
    Accepted
  3. Coimbra, Susana; Rocha, Susana; D. Viana, Sofia; Rebelo, Rute; Petronila Rocha-Pereira; Valente, Maria João; Catarino, Cristina; et al. Corresponding author: Coimbra, Susana. "Short-term and long-term effects of gadolinium and gadoteric acid exposure on rat kidney and liver functions". Paper presented in III 1H-TOXRUN International Congress 2024, Porto, 2024.
    Accepted
  4. Coimbra, Susana; Rocha, Susana; D. Viana, Sofia; Rebelo, Rute; Petronila Rocha-Pereira; Valente, Maria João; Catarino, Cristina; et al. Corresponding author: Coimbra, Susana. "Gadolinium and gadoteric acid exposure induce long-term down-regulation in erythroid-related genes". Paper presented in III 1H-TOXRUN International Congress 2024, Porto, 2024.
    Accepted
  5. Valente, Maria João; Rocha, Susana; Lousa, Irina; Reis, Flávio; Nunes, Sara; Viana, Sofia; Preguiça, Inês; et al. "Panel of sensitive biomarkers of the primary response to renal injury for an early diagnosis of chronic kidney disease". 2020.
    10.1093/ndt/gfaa142.P0739
  6. Coimbra, S; Reis, F; Nunes, S; Viana, S; Valente, MJ; Rocha, S; Catarino, C; et al. "EFFECTS OF STATINS THERAPY ON LDL SUBFRACTIONS AND INFLAMMATION, IN END-STAGE RENAL DISEASE PATIENTS ON DIALYSIS". 2019.
    Published • 10.1093/ndt/gfz106.fp730
  7. Garrido, P; Costa, E; Parada, B; Teixeira, M; Rodrigues, P; Sereno, J; Teixeira de Lemos, E; et al. "Efeitos não hematológicos da eritropoietina num modelo de insudficiência renal induzida por nefrectomia". Paper presented in VIII Congresso de Análises Clínicas e Saúde Pública da sociedade Portuguesa de Bianalistas clínicos, Coimbra, 2010.
    Published
  8. Garrido, P; Reis, F; Teixeira Lemos, E; Costa, E; Parada, B; Piloto, N; Sereno, J; et al. "Recombinant human erythropoietin therapy has beneficial cardio-renal effects on moderate stages of chronic renal failure in the rat". 2009.
  9. Piloto, N; Reis, F; Teixeira, HM; Teixeira Lemos, E; Parada, B; Garrido, P; Sereno, J; et al. "Recombinant human erythropoietin doping in sports - cardiovascular effects in chronic and acute aerobic exercise in an animal model". 2009.
Conference poster
  1. Pedro Vieira; Preguiça, Inês; Alves, André; Jesus, Ângela; Costa, Vânia; Viana SD; Reis, F; Paiva-Martins, Fátima. "Protective effect of oleacein in the apoE-KO Mice Model of Atherosclerosis". Paper presented in 4th International Symposium on Lipid Oxidation and Antioxidants 2022, 2022.
  2. Ramôa, J; Lousa, Irina; Viana, S; Reis, F; Belo, Luís Filipe Barbosa Amado; Alice Santos-Silva; Coimbra, Susana. "Estadiamento da doença renal crónica - alterações histológicas num modelo animal". Paper presented in APCF-TOXRUN International Congress 2022, 2022.
  3. Nunes, Sara; Viana, Sofia D.; Preguiça, Inês; Alves, André; Fernandes, Rosa; Jarak, Ivana; Carvalho, Rui A.; et al. "Blueberry juice prevents prediabetes progression in a hypercaloric diet-induced rat model through the modulation of hepatic mitochondrial bioenergetics and metabolic pathways.". Paper presented in 1º Congresso da Rede de Instituições do Ensino Superior para a Salvaguarda da Dieta Mediterrânica, 2021.
  4. Nunes, Sara; Viana, Sofia D.; Alves, André; Preguiça, Inês; Fernandes, Rosa; Rolo, Anabela Pinto; Palmeira, Carlos; et al. "Impacto de uma estratégia não-farmacológica na disfunção hepática pré-diabética - estudo do sumo de mirtilos em ratos alimentados com dieta hipercalórica.". Paper presented in 16.º Congresso Português de Diabetes, Vilamoura, Portugal, 2020.
  5. Alves, André; Preguiça, Inês; Barbosa, Adelaide; Vieira, Pedro; Martins, Diana; Nunes, Sara; Viana, Sofia D.; Reis, Flávio. "Efeitos renais do sumo de mirtilo num modelo de rato pré-diabético induzido por dieta hipercalórica.". Paper presented in 16º Congresso Português de Diabetes, Viamoura, Portugal, 2020.
  6. Espadinha, Margarida; Valentina Barcherini; Lopes, Elizabeth A.; Raimundo, Liliana; Gomes, Sara; Loureiro, Joana; Reis, Flávio. "New small-molecule dual inhibitors of the p53-MDM2/X interactions to reactivate the p53 pathway". Paper presented in VIII EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry, 2019.
  7. Nunes, Sara; Viana, Sofia D.; Reis, Flávio. "Uma abordagem nutracêutica dirigida à pré-diabetes baseada no sumo de mirtilo ¿ Impacto no perfil metabólico e na integridade da barreira intestinal num modelo animal induzido por dieta hipercalórica". Paper presented in 15º Congresso Português de Diabetes. Vilamoura, Portugal 8-10 de Março, 2019., 2019.
  8. Nunes, Sara; Viana, SD; Alves, André; Preguiça, Inês; Reis, Flávio. "Long-term effects of blueberry juice supplementation on hepatic mitochondrial function in healthy rats.". Paper presented in Centre for Innovative Biomedicine and Biotechnology (CIBB) Congress, Coimbra, 2019.
  9. Barbosa, Adelaide; Alves, André; Nunes, Sara; Preguiça, Inês; Viana, Sofia D.; Reis, Flávio; Viana SD; Reis, Flávio. "Effects of blueberry juice in a rat model of early diabetic nephropathy induced by high-fat diet.". Paper presented in Centre for Innovative Biomedicine and Biotechnology (CIBB) Congress, Coimbra, 2019.
  10. Preguiça, Inês; Martins, Beatriz; Nunes, Sara; Alves, André; Palavra, Filipe; Fernandes, Rosa; Santos, Sónia; et al. ""A novel semi-solid pill for voluntary oral drug administration in experimental rodents"". Paper presented in Centre for Innovative Biomedicine and Biotechnology (CIBB) Congress., 2019.
    10.1177/0023677219839199
  11. Reis, Flávio; Nunes, Sara; Sofia D. Viana; Burgeiro, Ana; Carvalho, Eugenia; Pereira, Frederico C; André, Maria Alexandra; Castanheira, Joaquim. "Alterações cardíacas precoces num modelo de pré-diabetes induzida por dieta hipercalórica - estudo molecular e de imagem funcional.". Paper presented in 14º Congresso Português de Diabetes. Algarve, Portugal 9-11 de Março, 2018, 2018.
  12. Ribeiro, S; Sameiro-Faria, M; Rodrigues, S; Nascimento, H; Fernandes, J; Rocha, S; Rocha-Pereira, P; et al. "On-line hemodiafiltration is associated with improved dialysis adequacy, iron availability, lipidic profile and nutritional status". Paper presented in Encontro Renal 2013, 2013.
  13. Garrido, P; Fernandes, J; Ribeiro, S; Vala, H; Parada, B; Alves, R; Belo, L; et al. "Iron metabolism in resistance to rhEPO due to the development of anti-EPO antibodies in a rat model of chronic renal failure". Paper presented in 50th ERA-EDTA Congress, 2013.
  14. Kohlova, M; Ribeiro, S; Sameiro-Faria, M; Rocha-Pereira, P; Fernandes, J; Reis, F; Miranda, V; et al. "Hemodialysis to onli-hemodiafiltration change is associated to a decrease in circulating cell-free DNA levels". Paper presented in 50th ERA-EDTA Congress, 2013.
  15. Costa, E; Ribeiro, S; Sameiro-Faria, M; Rocha-Pereira, P; Kohlova, M; Fernandes, J; Reis, F; et al. "Circulating cell-free DNA levels in hemodialysis patients and its association with iron metabolism, inflammation and rhEPO therapy". Paper presented in 50th ERA-EDTA Congress, 2013.
  16. Sameiro-Faria, M; Kohlova, M; Ribeiro, S; Rocha-Pereira, P; Fernandes, J; Nascimento, H; Reis, F; et al. "Potential beneficial effects of bilirubin in hemodialysis patients". Paper presented in 50th ERA-EDTA Congress, 2013.
  17. Sameiro-Faria, M; Ribeiro, S; Kohlova, M; Rocha-Pereira, P; Fernandes, J; Nascimento, H; Reis, F; et al. "Body mass index and resistance to rhEPO therapy in maintenance hemodialysis patients". Paper presented in 50th ERA-EDTA Congress, 2013.
  18. Garrido, P; Fernandes, J; Ribeiro, S; Vala, H; Parada, B; Alves, R; Belo, L; et al. "The 5/6 nephrectomized rat as a good model to study chronic kidney disease". Paper presented in 50th ERA-EDTA Congress, 2013.
  19. Ribeiro, S; Sameiro-Faria, M; Melo, F; Sereno, J; Freitas, I; Mendonça, M; Nascimento, H; et al. "PON1 activity in hemodialysis patients: genetic and non-genetic factors". Paper presented in 49th ERA-EDTA Congress, 2012.
  20. Ribeiro, S; Sameiro-Faria, M; Rocha, S; Rodrigues, S; Catarino, C; Reis, F; Nascimento, H; et al. "Erythrocyte membrane protein composition and band 3 profile in chronic kidney disease patients under on-line hemodiafiltration". Paper presented in 49th ERA-EDTA Congress, 2012.
  21. Garrido, P; Teixeira, M; Costa, E; Rodrigues-Santos, P; Parada, B; Belo, L; Alves, R; et al. "Early recombinat human erythropoietin treatment promotes cardiorenal cytoprotection in a rat model of chronic renal failure". Paper presented in 49th ERA-EDTA Congress, 2012.
  22. Coimbra, Susana; Oliveira, H; Reis, F; Belo, Luís Filipe Barbosa Amado; Quintanilha, A; Figueiredo, A; Petronila Rocha-Pereira; Alice Santos-Silva. "Cytokines and growth factors in Portuguese psoriatic patients: Relation with Body Mass Index". Paper presented in 20th EADV Congress, 2011.
  23. Sameiro-Faria, M; Costa, E; Rocha-Pereira, P; Borges, A; Nascimento, H; Mendonça, D; Amado, L; et al. "Inflammation, erythropoietic disturbances and the type of vascular access are the principal risk factors for mortality in HD patients: a prospective follow-up study of 12 months". Paper presented in XLVIII ERA-EDTA Congress, 2011.
  24. Sameiro-Faria, M; Ribeiro, S; Marques, C; Nascimento, H; Fernandes, J; Miranda, V; Mendonça, D; et al. "Prevalence of some hereditary thrombotic risk factors in a Portuguese population of haemodialyzed patients". Paper presented in XIX Congresso Nacional de Aterosclerose, 2011.
  25. Coimbra, Susana; Oliveira, H; Reis, F; Belo, Luís Filipe Barbosa Amado; Rocha, S; Quintanilha, A; Figueiredo, A; et al. "Erythocyte alterations in psoriasis vulgaris - relation with different types of therapy". Paper presented in XVII National Congress of Biochemistry, 2010.
  26. Coimbra, Susana; Oliveira, H; Reis, F; Belo, Luís Filipe Barbosa Amado; Rocha, S; Figueiredo, A; Teixeira, F; et al. "Associations between adipokines and other cardiovascular risk factors in patients with psoriasis vulgaris". Paper presented in XVII National Congress of Biochemistry, 2010.
  27. Coimbra, Susana; Oliveira, H; Reis, F; Belo, Luís Filipe Barbosa Amado; Rocha, S; Quintanilha, A; Figueiredo, A; et al. "Health-related quality of life in Portuguese psoriasis patients: relation with therapy and PASI". Paper presented in XI Congresso Nacional de Dermatologia e Venereologia, 2010.
  28. Coimbra, Susana; Oliveira, H; Reis, F; Belo, Luís Filipe Barbosa Amado; Rocha, S; Quintanilha, A; Figueiredo, A; et al. "Inflammatory markers in psoriasis vulgaris according to therapy and severity". Paper presented in XI Congresso Nacional de Dermatologia e Venereologia, 2010.
  29. Coimbra, Susana; Oliveira, H; Reis, F; Belo, Luís Filipe Barbosa Amado; Rocha, S; Quintanilha, A; Figueiredo, A; et al. "Cytokines and growth factors in Portuguese psoriatic patients - relation with PUVA and NBUVB therapy". Paper presented in XI Congresso Nacional de Dermatologia e Venereologia, 2010.
  30. Coimbra, Susana; Oliveira, H; Reis, F; Belo, Luís Filipe Barbosa Amado; Rocha, S; Figueiredo, A; Teixeira, F; et al. "Adipokine and CRP levels in Portuguese patients with psoriasis vulgaris". Paper presented in IV Workshop de Bioquímica Clínica, 2010.
  31. Mascarenhas-Melo, Filipa; Sereno, José Vitor Oliveira; Teixeira-Lemos, E.; Mega C; Vala, H; Fernandes R; Oliveira, Jorge; et al. "Rationale for dpp-4 inhibition by sitagliptin in the management of type 2 diabetes". Paper presented in 2nd National Meeting on Medicinal Chemistry /2enqt – SPQ, 2010.
  32. Sereno, José Vitor Oliveira; Cerejo, Raquel; Reis, F; Parada, Belmiro Ataíde da Costa; Teixeira de Lemos, E; Sereno, J; Garrido, P; et al. "Omega-3 fatty acids therapy for prevention of nitrosamine-induced bladder cancer in a rat model.". Paper presented in 2nd National Meeting on Medicinal Chemistry /2enqt, 2010.
  33. Costa, E; Swinkels, DW; Laarakkers, CM; Rocha-Pereira, P; Rocha, S; Reis, F; Teixeira, F; et al. "Hepcidin serum levels and its relationship with haematological data, iron status, inflammatory markers and rhEPO doses in haemodialysis patients". Paper presented in XLVII ERA-EDTA Congress 2010, 2010.
  34. Borges, A; Borges, M; Costa, Elísio; Nascimento, H; Sameiro-Faria, M; Miranda, V; Reis, F; et al. "Apoptosis of peripheral CD4+ T-lymphocytes is induced by the Hemodialysis procedure". Paper presented in 8th International conference on MECHANISMS OF CELL DEATH AND DISEASE: DRUG DEVELOPMENT, 2010.
  35. Sereno, J; Romão, AM; Costa, Elísio; Garrido, P; Teixeira de Lemos, E; Rocha-Pereira, P; Melo, F; et al. "Early versus late cyclosporin to sirolimus conversion in an animal model: potential cardiorenal benefits". Paper presented in XVII Congresso Nacional de Bioquímica, 2010.
  36. Teixeira, M; Rodrigues-Santos, P; Garrido, P; Costa, E; Parada, B; Sereno, J; Belo, L; et al. "Effect of recombinant human erythropoietin therapy on kidney and heart gene expression profile in a model of moderate chronic renal failure". Paper presented in XVII Congresso Nacional de Bioquímica, 2010.
  37. Sereno, José Vitor Oliveira; Garrido, P.; Costa, E.; Parada, Belmiro Ataíde da Costa; Rodrigues-Santos, P; Sereno, J.; Teixeira de Lemos, E.; et al. "Efeitos não hematológicos da eritropoietina num modelo de insuficiência renal induzida por nefrectomia". Paper presented in VIII Congresso de Análise Clínicas e Saúde Pública, 2010.
  38. Coimbra, Susana; Oliveira, H; Reis, F; Belo, Luís Filipe Barbosa Amado; Rocha, S; Figueiredo, A; Teixeira, F; et al. "Incidence of several cardiovascular risk factors in Portuguese psoriasis patients". Paper presented in 10º congresso Nacional de Dermatologia e Venereologia, 2008.
  39. Coimbra, Susana; Oliveira, H; Reis, F; Belo, Luís Filipe Barbosa Amado; Rocha, S; Figueiredo, A; Teixeira, F; et al. "Inflammatory response - association with psoriasis severity". Paper presented in 10º congresso Nacional de Dermatologia e Venereologia, 2008.
  40. Coimbra, Susana; Oliveira, H; Reis, F; Belo, Luís Filipe Barbosa Amado; Rocha, S; Figueiredo, A; Teixeira, F; et al. "Cardiovascular risk factors in psoriatic patients: a follow-up study". Paper presented in XVIth National Congress of Biochemistry, 2008.
  41. Coimbra, Susana; Castro, E; Petronila Rocha-Pereira; Oliveira, H; Belo, Luís Filipe Barbosa Amado; Reis, F; Rocha, S; et al. "Cardiovascular risk factors in association with psoriasis vulgaris". Paper presented in 17th European Academy of Dermatology Venereology Congress, 2008.
  42. Coimbra, Susana; Castro, E; Petronila Rocha-Pereira; Oliveira, H; Belo, Luís Filipe Barbosa Amado; Reis, F; Rocha, S; et al. "Risk for cardiovascular events in patients with psoriasis vulgaris". Paper presented in 3º Workshop em Bioquímica Clínica, 2008.
  43. Coimbra, Susana; Castro, E; Petronila Rocha-Pereira; Oliveira, H; Belo, Luís Filipe Barbosa Amado; Reis, F; Rocha, S; et al. "Inflammatory markers in psoriatic patients - a preliminary study". Paper presented in XVth National Congress of Biochemistry, 2006.
Edited book
  1. Reis, Flávio. BIOMARKERS OF CARDIOMETABOLIC RISK, INFLAMMATION AND DISEASE - Springer International Publishing. Springer International Publishing. 2015.
    Published • 10.1007/978-3-319-16018-4 • Editor
  2. Reis, Flávio. Frontiers in Drug Discovery: Erythropoietic Stimulating Agents. BENTHAM SCIENCE PUBLISHERS. 2013.
    Published • 10.2174/97816080574741130101 • Editor
Journal article
  1. Lagoa R; Rajan L; Violante C; Babiaka SB; Marques-da-Silva D; Kapoor B; Reis F; Atanasov AG. "Application of curcuminoids in inflammatory, neurodegenerative and aging conditions - Pharmacological potential and bioengineering approaches to improve efficiency.". Biotechnology advances (2025): http://europepmc.org/abstract/med/40157560.
    10.1016/j.biotechadv.2025.108568
  2. Susana Coimbra; S. Rocha; Sofia Viana; Rute Rebelo; Petronila Rocha-Pereira; Irina Lousa; Maria João Valente; et al. "Gadoteric Acid and Gadolinium: Exploring Short- and Long-Term Effects on Healthy Animals". Journal of Xenobiotics (2025): https://www.mdpi.com/2039-4713/15/2/34.
    10.3390/jox15020034
  3. Costa CM; Pedrosa SS; Kirkland JL; Reis F; Madureira AR. "The senotherapeutic potential of phytochemicals for age-related intestinal disease.". Ageing research reviews (2024): http://europepmc.org/abstract/med/39638096.
    10.1016/j.arr.2024.102619
  4. Sousa A; Amaro A; Costa VM; Azevedo R; Oliveira S; Viana S; Reis F; et al. "Exploring quercetin's protective potential against the pro-inflammatory effects of silver nanoparticles in C57BL/6J mice.". Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association (2024): http://europepmc.org/abstract/med/39510241.
    10.1016/j.fct.2024.115081
  5. Azevedo-Silva J; Amorim M; Tavares-Valente D; Sousa P; Mohamath R; Voigt EA; Guderian JA; et al. "Exploring yeast glucans for vaccine enhancement: Sustainable strategies for overcoming adjuvant challenges in a SARS-CoV-2 model.". European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V (2024): http://europepmc.org/abstract/med/39461571.
    10.1016/j.ejpb.2024.114538
  6. Rosendo-Silva D; Lopes E; Monteiro-Alfredo T; Falcão-Pires I; Eickhoff H; Viana S; Reis F; et al. "The adipose tissue melanocortin 3 receptor is targeted by ghrelin and leptin and may be a therapeutic target in obesity.". Molecular and cellular endocrinology (2024): http://europepmc.org/abstract/med/39293775.
    10.1016/j.mce.2024.112367
  7. Rosendo-Silva, Daniela; Gomes, Pedro Bastos; Rodrigues, Tiago; Viana, Sofia; da Costa, André Nogueira; Scherer, Philipp E.; Reis, Flávio; et al. "Clinical and molecular profiling of human visceral adipose tissue reveals impairment of vascular architecture and remodeling as an early hallmark of dysfunction". Metabolism 153 (2024): 155788. http://dx.doi.org/10.1016/j.metabol.2024.155788.
    Open access • Published • 10.1016/j.metabol.2024.155788
  8. Reis, Flávio; Fernandes, Rosa. "Molecular Pharmacology in Diabetes". International Journal of Molecular Sciences 25 5 (2024): 3051. http://dx.doi.org/10.3390/ijms25053051.
    10.3390/ijms25053051
  9. Ferreira, Gonçalo; Vieira, Pedro; Alves, André; Nunes, Sara; Preguiça, Inês; Martins-Marques, Tânia; Ribeiro, Tânia; et al. "Effect of Blueberry Supplementation on a Diet-Induced Rat Model of Prediabetes—Focus on Hepatic Lipid Deposition, Endoplasmic Stress Response and Autophagy". Nutrients 16 4 (2024): 513. http://dx.doi.org/10.3390/nu16040513.
    10.3390/nu16040513
  10. Das, Anindita; Reis, Flávio. "mTOR Signaling: New Insights into Cancer, Cardiovascular Diseases, Diabetes and Aging". International Journal of Molecular Sciences 24 17 (2023): 13628. http://dx.doi.org/10.3390/ijms241713628.
    Open access • Published • 10.3390/ijms241713628
  11. Sousa, Adelaide; Azevedo, Rui; Costa, Vera Marisa; Oliveira, Sara; Preguiça, Inês; Viana, Sofia; Reis, Flávio; et al. "Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice". Archives of Toxicology 97 10 (2023): 2643-2657. http://dx.doi.org/10.1007/s00204-023-03558-5.
    Open access • Published • 10.1007/s00204-023-03558-5
  12. Garcia, Karina; Alves, André; Ribeiro-Rodrigues, Teresa M.; Reis, Flávio; Viana, Sofia. "Analysis of Fluorescent-Stained Lipid Droplets with 3D Reconstruction for Hepatic Steatosis Assessment". Journal of Visualized Experiments 196 (2023): http://dx.doi.org/10.3791/65206.
    Open access • Published • 10.3791/65206
  13. Reis, Flávio. "Gut microbiota dysbiosis and cardiovascular disease – The chicken and the egg". Revista Portuguesa de Cardiologia 42 6 (2023): 553-555. http://dx.doi.org/10.1016/j.repc.2023.03.004.
    Open access • Published • 10.1016/j.repc.2023.03.004
  14. Alves-Silva, Jorge M.; Zuzarte, Mónica; Marques, Carla; Viana, Sofia; Preguiça, Inês; Baptista, Rui; Ferreira, Cátia; et al. "Reply to the Comment on “1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis”". Pharmacological Research 191 (2023): 106623. http://dx.doi.org/10.1016/j.phrs.2022.106623.
    Published • 10.1016/j.phrs.2022.106623
  15. Rosendo-Silva, Daniela; Viana, Sofia; Carvalho, Eugénia; Reis, Flávio; Matafome, Paulo. "Are gut dysbiosis, barrier disruption, and endotoxemia related to adipose tissue dysfunction in metabolic disorders? Overview of the mechanisms involved". Internal and Emergency Medicine 18 5 (2023): 1287-1302. http://dx.doi.org/10.1007/s11739-023-03262-3.
    Open access • Published • 10.1007/s11739-023-03262-3
  16. Lousa, Irina; Reis, Flávio; Viana, Sofia; Vieira, Pedro; Vala, Helena; Belo, Luís; Santos-Silva, Alice. "TNFR2 as a Potential Biomarker for Early Detection and Progression of CKD". Biomolecules 13 3 (2023): 534. http://dx.doi.org/10.3390/biom13030534.
    Open access • Published • 10.3390/biom13030534
  17. Garcia, Karina; Ferreira, Gonçalo; Reis, Flávio; Viana, Sofia. "Impact of Dietary Sugars on Gut Microbiota and Metabolic Health". Diabetology 3 4 (2022): 549-560. http://dx.doi.org/10.3390/diabetology3040042.
    Open access • Published • 10.3390/diabetology3040042
  18. Palavra, Filipe; Viana, Sofia D.; Henriques, Sara; Dinis, João; Martins, João; Madeira, Maria H.; Santiago, Raquel; et al. "Defining milestones for the study of remyelination using the cuprizone mouse model: How early is early?". Multiple Sclerosis and Related Disorders 63 (2022): 103886. http://dx.doi.org/10.1016/j.msard.2022.103886.
    Open access • Published • 10.1016/j.msard.2022.103886
  19. Alves-Silva, Jorge M.; Zuzarte, Mónica; Marques, Carla; Viana, Sofia; Preguiça, Inês; Baptista, Rui; Ferreira, Cátia; et al. "1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis". Pharmacological Research 180 (2022): 106151. http://dx.doi.org/10.1016/j.phrs.2022.106151.
    Open access • Published • 10.1016/j.phrs.2022.106151
  20. Amorim, Madania; Martins, Beatriz; Caramelo, Francisco; Gonçalves, Conceição; Trindade, Grimalde; Simão, Jorge; Barreto, Patrícia; et al. "Putative Biomarkers in Tears for Diabetic Retinopathy Diagnosis". Frontiers in Medicine 9 (2022): http://dx.doi.org/10.3389/fmed.2022.873483.
    Open access • Published • 10.3389/fmed.2022.873483
  21. Lousa, Irina; Belo, Luís; Valente, Maria João; Rocha, Susana; Preguiça, Inês; Rocha-Pereira, Petronila; Beirão, Idalina; et al. "Inflammatory biomarkers in staging of chronic kidney disease: elevated TNFR2 levels accompanies renal function decline". Inflammation Research 71 5-6 (2022): 591-602. http://dx.doi.org/10.1007/s00011-022-01574-2.
    Open access • Published • 10.1007/s00011-022-01574-2
  22. Lousa, Irina; Reis, Flávio; Santos-Silva, Alice; Belo, Luís. "The Signaling Pathway of TNF Receptors: Linking Animal Models of Renal Disease to Human CKD". International Journal of Molecular Sciences 23 6 (2022): 3284. http://dx.doi.org/10.3390/ijms23063284.
    Published • 10.3390/ijms23063284
  23. Sara Nunes; Sofia D. Viana; Inês Preguiça; André Alves; R. Fernandes; Teodoro, J.S.; Patrícia Matos; et al. "Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics". Nutrients (2021): https://www.mdpi.com/2072-6643/13/12/4192.
    10.3390/nu13124192
  24. Sara Nunes; Pedro Vieira; Pedro Gomes; Sofia Domingues Viana; Reis F. "Blueberry as An Attractive Functional Fruit to Prevent (Pre)Diabetes Progression". Antioxidants (2021): https://www.mdpi.com/2076-3921/10/8/1162.
    10.3390/antiox10081162
  25. Susana Coimbra; Reis F; Maria João Valente; S. Rocha; Cristina Catarino; Petronila Rocha-Pereira; Maria Sameiro-Faria; et al. "Subpopulations of High-Density Lipoprotein: Friends or Foes in Cardiovascular Disease Risk in Chronic Kidney Disease?". Biomedicines (2021): https://www.mdpi.com/2227-9059/9/5/554.
    10.3390/biomedicines9050554
  26. Nuno Henrique Franco; Sónia Miranda; Nóra Kovács; Attila Nagy; Bùi Qu¿c Thi¿n; Reis F; Orsolya Varga. "Assessing Scientific Soundness and Translational Value of Animal Studies on DPP4 Inhibitors for Treating Type 2 Diabetes Mellitus". Biology (2021): https://www.mdpi.com/2079-7737/10/2/155.
    10.3390/biology10020155
  27. Ramos, H.; Soares, M.I.L.; Silva, J.; Raimundo, L.; Calheiros, J.; Gomes, C.; Reis, F.; et al. "A selective p53 activator and anticancer agent to improve colorectal cancer therapy". Cell Reports 35 2 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85104050337&partnerID=MN8TOARS.
    10.1016/j.celrep.2021.108982
  28. Pandey, A.K.; Kumar, S.; Reis, F.. "Editorial: Combating Redox Imbalance-Associated Complications With Natural Products". Frontiers in Pharmacology 12 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85121004209&partnerID=MN8TOARS.
    10.3389/fphar.2021.802750
  29. Azul, A.M.; Almendra, R.; Quatorze, M.; Loureiro, A.; Reis, F.; Tavares, R.; Mota-Pinto, A.; et al. "Unhealthy lifestyles, environment, well-being and health capability in rural neighbourhoods: a community-based cross-sectional study". BMC public health 21 1 (2021): 1628-1628. http://www.scopus.com/inward/record.url?eid=2-s2.0-85115819445&partnerID=MN8TOARS.
    10.1186/s12889-021-11661-4
  30. Irina Lousa; Reis F; Idalina Beirão; Rui Alves; Luís Belo; Alice Santos-Silva. "New Potential Biomarkers for Chronic Kidney Disease Management—A Review of the Literature". International Journal of Molecular Sciences (2020): https://www.mdpi.com/1422-0067/22/1/43.
    10.3390/ijms22010043
  31. Carolina Ferreira; Sofia D. Viana; Reis F. "Is Gut Microbiota Dysbiosis a Predictor of Increased Susceptibility to Poor Outcome of COVID-19 Patients? An Update". Microorganisms (2020): https://www.mdpi.com/2076-2607/9/1/53.
    10.3390/microorganisms9010053
  32. Picó C; Reis F; Egas C; Mathias P; Matafome P. "Lactation as a programming window for metabolic syndrome.". European journal of clinical investigation (2020): http://europepmc.org/abstract/med/33350459.
    10.1111/eci.13482
  33. Sara Nunes; Sofia D. Viana; Inês Preguiça; André Alves; R. Fernandes; Teodoro, J.S.; Artur Figueirinha; et al. "Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats". Pharmaceutics (2020): https://www.mdpi.com/1999-4923/12/11/1094.
    10.3390/pharmaceutics12111094
  34. Carolina Ferreira; Sofia D. Viana; Reis F. "Gut Microbiota Dysbiosis–Immune Hyperresponse–Inflammation Triad in Coronavirus Disease 2019 (COVID-19): Impact of Pharmacological and Nutraceutical Approaches". Microorganisms (2020): https://www.mdpi.com/2076-2607/8/10/1514.
    10.3390/microorganisms8101514
  35. Beatriz Martins; Madania Amorim; Reis F; António F Ambrósio; R. Fernandes. "Extracellular Vesicles and MicroRNA: Putative Role in Diagnosis and Treatment of Diabetic Retinopathy". Antioxidants (2020): https://www.mdpi.com/2076-3921/9/8/705.
    10.3390/antiox9080705
  36. Viana SD; Nunes S; Reis F. "ACE2 imbalance as a key player for the poor outcomes in COVID-19 patients with age-related comorbidities - Role of gut microbiota dysbiosis.". Ageing research reviews (2020): http://europepmc.org/abstract/med/32683039.
    10.1016/j.arr.2020.101123
  37. Preguiça I; Alves A; Nunes S; Fernandes R; Gomes P; Viana SD; Reis F. "Diet-induced rodent models of obesity-related metabolic disorders-A guide to a translational perspective.". Obesity reviews : an official journal of the International Association for the Study of Obesity (2020): http://europepmc.org/abstract/med/32691524.
    10.1111/obr.13081
  38. Sara Nunes; André Alves; Inês Preguiça; Adelaide Barbosa; Pedro Vieira; Fernando Mendes; Diana Martins; Sofia D. Viana; Reis F. "Crescent-Like Lesions as an Early Signature of Nephropathy in a Rat Model of Prediabetes Induced by a Hypercaloric Diet". Nutrients (2020): https://www.mdpi.com/2072-6643/12/4/881.
    10.3390/nu12040881
  39. Reis, Flávio. "Diet-Induced Rodent Models of Diabetic Peripheral Neuropathy, Retinopathy and Nephropathy". Nutrients (2020): http://dx.doi.org/10.3390/nu12010250.
    10.3390/nu12010250
  40. Gomes P; Leal H; Mendes AF; Reis F; Cavadas C. "Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic Diseases.". Trends in pharmacological sciences (2019): http://europepmc.org/abstract/med/31704173.
    10.1016/j.tips.2019.09.003
  41. Gomes P; Viana SD; Nunes S; Rolo AP; Palmeira CM; Reis F. "The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders.". Ageing research reviews (2019): http://europepmc.org/abstract/med/31740222.
    10.1016/j.arr.2019.100983
  42. Amit Kumar Singh; Célia Cabral; Ramesh Kumar; Risha Ganguly; Harvesh Kumar Rana; ASHUTOSH GUPTA; Maria Rosaria Lauro; et al. "Beneficial Effects of Dietary Polyphenols on Gut Microbiota and Strategies to Improve Delivery Efficiency". Nutrients (2019): https://www.mdpi.com/2072-6643/11/9/2216.
    10.3390/nu11092216
  43. Marques C; Gonçalves A; Pereira PMR; Almeida D; Martins B; Fontes-Ribeiro C; Reis F; Fernandes R. "The dipeptidyl peptidase 4 inhibitor sitagliptin improves oxidative stress and ameliorates glomerular lesions in a rat model of type 1 diabetes.". Life sciences (2019): http://europepmc.org/abstract/med/31398418.
    10.1016/j.lfs.2019.116738
  44. Gomes S; Bosco B; Loureiro JB; Ramos H; Raimundo L; Soares J; Nazareth N; et al. "SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma.". Cancers (2019): http://europepmc.org/abstract/med/31405179.
    10.3390/cancers11081151
  45. Reis F; Sá-Moura B; Guardado D; Couceiro P; Catarino L; Mota-Pinto A; Veríssimo MT; et al. "Development of a Healthy Lifestyle Assessment Toolkit for the General Public.". Frontiers in medicine (2019): http://europepmc.org/abstract/med/31316985.
    10.3389/fmed.2019.00134
  46. Das A; Reis F; Mishra PK. "mTOR Signaling in Cardiometabolic Disease, Cancer, and Aging 2018.". Oxidative medicine and cellular longevity (2019): http://europepmc.org/abstract/med/30863483.
    10.1155/2019/9692528
  47. Coimbra S; Reis F; Nunes S; Viana S; Valente MJ; Rocha S; Catarino C; et al. "The Protective Role of Adiponectin for Lipoproteins in End-Stage Renal Disease Patients: Relationship with Diabetes and Body Mass Index.". Oxidative medicine and cellular longevity (2019): http://europepmc.org/abstract/med/30911344.
    10.1155/2019/3021785
  48. Coimbra S; Reis F; Ferreira C; Nunes S; Viana S; Catarino A; Rocha-Pereira P; et al. "Weight loss achieved by bariatric surgery modifies high-density lipoprotein subfractions and low-density lipoprotein oxidation towards atheroprotection.". Clinical biochemistry (2018): http://europepmc.org/abstract/med/30342017.
    10.1016/j.clinbiochem.2018.10.007
  49. Fernandes R; Viana SD; Nunes S; Reis F. "Diabetic gut microbiota dysbiosis as an inflammaging and immunosenescence condition that fosters progression of retinopathy and nephropathy.". Biochimica et biophysica acta. Molecular basis of disease (2018): http://europepmc.org/abstract/med/30287404.
    10.1016/j.bbadis.2018.09.032
  50. Viana SD; Reis F; Alves R. "Therapeutic Use of mTOR Inhibitors in Renal Diseases: Advances, Drawbacks, and Challenges.". Oxidative medicine and cellular longevity (2018): http://europepmc.org/abstract/med/30510618.
    10.1155/2018/3693625
  51. Alves MRP; Boia R; Campos EJ; Martins J; Nunes S; Madeira MH; Santiago AR; et al. "Subtle thinning of retinal layers without overt vascular and inflammatory alterations in a rat model of prediabetes.". Molecular vision (2018): http://europepmc.org/abstract/med/29853770.
  52. Lousa I; Nascimento H; Rocha S; Catarino C; Reis F; Rêgo C; Santos-Silva A; et al. "Influence of the 6-month physical activity programs on renal function in obese boys.". Pediatric research (2018): http://europepmc.org/abstract/med/29638229.
    10.1038/pr.2018.15
  53. Teodoro JS; Nunes S; Rolo AP; Reis F; Palmeira CM. "Therapeutic Options Targeting Oxidative Stress, Mitochondrial Dysfunction and Inflammation to Hinder the Progression of Vascular Complications of Diabetes.". Frontiers in physiology (2018): http://europepmc.org/abstract/med/30705633.
    10.3389/fphys.2018.01857
  54. Reis, Flávio. "Bridging health and social care with the citizens – the case of eit health project “HeaLIQs4Cities” and “praça vida+”, in Portugal". Care Weekly 2 (2018): 21-24.
    Open access • Published
  55. Alves, M.R.P.; Boia, R.; Campos, E.J.; Martins, J.; Nunes, S.; Madeira, M.H.; Santiago, A.R.; et al. "Subtle thinning of retinal layers without overt vascular and inflammatory alterations in a rat model of prediabetes". Molecular Vision 24 (2018): 353-366. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050808197&partnerID=MN8TOARS.
  56. Sá-Moura, Bebiana; Couceiro, Patrícia; Catarino, Luis; Guardado, Diana; de Brito, Maja; Gomes, Bárbara; Tavares, Rui; et al. "BRIDGING HEALTH AND SOCIAL CARE WITH THE CITIZENS- THE CASE OF EIT HEALTH PROJECT HEALIQS4CITIES AND PRAÇA VIDA+, IN PORTUGAL". Care Weekly 2 (2018): 21-24. https://www.care-weekly.com/2642-bridging-health-and-social-care-with-the-citizens-the-case-of-eit-health-project-healiqs4cities-and-praca-vida-in-portugal.html.
  57. Reis, Flávio. "Discovery of a small-molecule protein kinase Cd-selective activator with promising application in colon cancer therapy". Cell Death & Disease (2017):
    10.1038/s41419-017-0154-9
  58. Reis, Flávio. "Therapeutic strategies targeting oxidative stress to improve dyslipidemia and left ventricular hypertrophy.". Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology (2017): http://europepmc.org/abstract/med/28826936.
    10.1016/j.repc.2017.07.003
  59. Reis, Flávio. "Glucose and Lipid Dysmetabolism in a Rat Model of Prediabetes Induced by a High-Sucrose Diet.". Nutrients (2017): http://europepmc.org/abstract/med/28635632.
    10.3390/nu9060638
  60. Soares J; Espadinha M; Raimundo L; Ramos H; Gomes AS; Gomes S; Loureiro JB; et al. "DIMP53-1: A novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties.". (2017): http://europepmc.org/abstract/med/28296148.
    10.1002/1878-0261.12051
  61. Nunes, S.; Madureira, A.R.; Campos, D.; Sarmento, B.; Gomes, A.M.; Pintado, M.; Reis, F.. "Solid lipid nanoparticles as oral delivery systems of phenolic compounds: Overcoming pharmacokinetic limitations for nutraceutical applications". Critical Reviews in Food Science and Nutrition 57 9 (2017): 1863-1873. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014884555&partnerID=MN8TOARS.
    10.1080/10408398.2015.1031337
  62. Nunes, S.; Madureira, A.R.; Campos, D.; Sarmento, B.; Gomes, A.M.; Pintado, M.; Reis, F.. "Therapeutic and nutraceutical potential of rosmarinic acid—Cytoprotective properties and pharmacokinetic profile". Critical Reviews in Food Science and Nutrition 57 9 (2017): 1799-1806. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014885468&partnerID=MN8TOARS.
    10.1080/10408398.2015.1006768
  63. Reis, Flávio. "mTOR Signaling in Cardiometabolic Disease, Cancer, and Aging.". Oxidative medicine and cellular longevity (2017): http://europepmc.org/abstract/med/28770023.
    10.1155/2017/6018675
  64. Reis, Flávio. "Renoprotective Effects of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin: A Review in Type 2 Diabetes.". Journal of diabetes research (2017): http://europepmc.org/abstract/med/29098166.
    10.1155/2017/5164292
  65. Palavra F; Robalo C; Reis F. "Recent Advances and Challenges of mTOR Inhibitors Use in the Treatment of Patients with Tuberous Sclerosis Complex.". (2017): http://europepmc.org/abstract/med/28386314.
    10.1155/2017/9820181
  66. Fernandes, João; Ribeiro, Sandra; Nunes, Sara; Garrido, Patricia; Sereno, José Vitor Oliveira; Costa, Elísio; Reis, Flávio; Santos-Silva, Alice. "Hypoxia inducible factors play a major role in renal and hepatic erythropoietin regulation in an animal model of anemia associated with chronic kidney disease.". Bol Soc Port Hemorreol Microcir 32 2 (2017): 5-19.
    Published
  67. García-Casarrubios E; de Moura C; Arroba AI; Pescador N; Calderon-Dominguez M; Garcia L; Herrero L; et al. "Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes.". (2016): http://europepmc.org/abstract/med/27686967.
    10.1016/j.bbalip.2016.09.016
  68. Ferreira-Teixeira M; Paiva-Oliveira D; Parada B; Alves V; Sousa V; Chijioke O; Münz C; et al. "Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells.". (2016): http://europepmc.org/abstract/med/27769244.
  69. Ribeiro S; Garrido P; Fernandes J; Rocha S; Rocha-Pereira P; Costa E; Belo L; Reis F; Santos-Silva A. "Recombinant human erythropoietin-induced erythropoiesis regulates hepcidin expression over iron status in the rat.". (2016): http://europepmc.org/abstract/med/27282570.
    10.1016/j.bcmd.2016.04.008
  70. João AL; Reis F; Fernandes R. "The incretin system ABCs in obesity and diabetes - novel therapeutic strategies for weight loss and beyond.". (2016): http://europepmc.org/abstract/med/27125902.
    10.1111/obr.12421
  71. Palavra F; Almeida L; Ambrósio AF; Reis F. "Obesity and brain inflammation: a focus on multiple sclerosis.". (2016): http://europepmc.org/abstract/med/26783119.
    10.1111/obr.12363
  72. Ribeiro S; Garrido P; Fernandes J; Rocha-Pereira P; Costa E; Belo L; Reis F; Santos-Silva A. "Liver iron is a major regulator of hepcidin gene expression via BMP/SMAD pathway in a rat model of chronic renal failure under treatment with high rHuEPO doses.". (2016): http://europepmc.org/abstract/med/26990350.
    10.1002/biof.1275
  73. Ribeiro S; Garrido P; Fernandes J; Vala H; Rocha-Pereira P; Costa E; Belo L; Reis F; Santos-Silva A. "Pathological and molecular mechanisms underlying resistance to recombinant human erythropoietin therapy in the remnant kidney rat model of chronic kidney disease associated anemia.". (2016): http://europepmc.org/abstract/med/27039028.
  74. Castro AL; Tarelho S; Dias M; Reis F; Teixeira HM. "Comparison of endogenous GHB concentrations in blood and hair in death cases with emphasis on the post mortem interval.". (2016): http://europepmc.org/abstract/med/26846768.
  75. Lemos C; Rial D; Gonçalves FQ; Pires J; Silva HB; Matheus FC; da Silva AC; et al. "High sucrose consumption induces memory impairment in rats associated with electrophysiological modifications but not with metabolic changes in the hippocampus.". (2016): http://europepmc.org/abstract/med/26704636.
    10.1016/j.neuroscience.2015.12.018
  76. Castro AL; Tarelho S; Dias M; Reis F; Teixeira HM. "A fast and reliable method for GHB quantitation in whole blood by GC-MS/MS (TQD) for forensic purposes.". (2016): http://europepmc.org/abstract/med/26678181.
    10.1016/j.jpba.2015.11.038
  77. Ribeiro S; Garrido P; Fernandes J; Vala H; Rocha-Pereira P; Costa E; Belo L; Reis F; Santos-Silva A. "Impaired renal endothelial nitric oxide synthase and reticulocyte production as modulators of hypertension induced by rHuEPO in the rat.". (2016): http://europepmc.org/abstract/med/26924494.
    10.1016/j.lfs.2016.02.088
  78. Madureira AR; Nunes S; Campos DA; Fernandes JC; Marques C; Zuzarte M; Gullón B; et al. "Safety profile of solid lipid nanoparticles loaded with rosmarinic acid for oral use: in vitro and animal approaches.". (2016): http://europepmc.org/abstract/med/27536103.
    10.2147/ijn.s104623
  79. Reis, Flávio. "Renal risk-benefits determinants of recombinant human erythropoietin therapy in the remnant kidney rat model – hypertension, anaemia, infammation and drug dose". Clin Exp Pharmacol and Physiol (2016):
    10.1111/1440-1681.12541
  80. Ferreira-Teixeira, M.; Paiva-Oliveira, D.; Parada, B.; Alves, V.; Sousa, V.; Chijioke, O.; Münz, C.; et al. "Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells". BMC Medicine 14 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84992153376&partnerID=MN8TOARS.
    10.1186/s12916-016-0715-2
  81. Castro, A.L.; Tarelho, S.; Dias, M.; Reis, F.; Teixeira, H.M.. "Comparison of endogenous GHB concentrations in blood and hair in death cases with emphasis on the post mortem interval". International Journal of Legal Medicine 130 4 (2016): 959-965. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957591999&partnerID=MN8TOARS.
    10.1007/s00414-016-1321-8
  82. Ribeiro, S.; Belo, L.; Reis, F.; Santos-Silva, A.. "Iron therapy in chronic kidney disease: Recent changes, benefits and risks". Blood Reviews 30 1 (2016): 65-72. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960312577&partnerID=MN8TOARS.
    10.1016/j.blre.2015.07.006
  83. Ribeiro, S.; Garrido, P.; Fernandes, J.; Vala, H.; Rocha-Pereira, P.; Costa, E.; Belo, L.; Reis, F.; Santos-Silva, A.. "Pathological and molecular mechanisms underlying resistance to recombinant human erythropoietin therapy in the remnant kidney rat model of chronic kidney disease associated anemia". Biochimie 125 (2016): 150-162. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964388884&partnerID=MN8TOARS.
    10.1016/j.biochi.2016.03.012
  84. Soares J; Raimundo L; Pereira NA; Monteiro Â; Gomes S; Bessa C; Pereira C; et al. "Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule.". (2015): http://europepmc.org/abstract/med/26735173.
    10.18632/oncotarget.6775
  85. Ribeiro S; Belo L; Reis F; Santos-Silva A. "Iron therapy in chronic kidney disease: Recent changes, benefits and risks.". (2015): http://europepmc.org/abstract/med/26342303.
  86. Sereno J; Vala H; Nunes S; Rocha-Pereira P; Carvalho E; Alves R; Teixeira F; Reis F. "Cyclosporine A-induced nephrotoxicity is ameliorated by dose reduction and conversion to sirolimus in the rat.". (2015): http://europepmc.org/abstract/med/25903959.
  87. Garrido P; Ribeiro S; Fernandes J; Vala H; Rocha-Pereira P; Bronze-da-Rocha E; Belo L; et al. "Resistance to Recombinant Human Erythropoietin Therapy in a Rat Model of Chronic Kidney Disease Associated Anemia.". (2015): http://europepmc.org/abstract/med/26712750.
    10.3390/ijms17010028
  88. Reis, Flávio. "Functional and molecular characterization of cancer stem-like cells in bladder cancer: a potential signature for muscle-invasive tumors.". Oncotarget (2015):
    10.18632/oncotarget.5517
  89. Garrido P; Ribeiro S; Fernandes J; Vala H; Bronze-da-Rocha E; Rocha-Pereira P; Belo L; et al. "Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model.". (2015): http://europepmc.org/abstract/med/25867633.
    10.1371/journal.pone.0124048
  90. Godinho R; Mega C; Teixeira-de-Lemos E; Carvalho E; Teixeira F; Fernandes R; Reis F. "The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A "Me Too" or "the Special One" Antidiabetic Class?". (2015): http://europepmc.org/abstract/med/26075286.
    10.1155/2015/806979
  91. Madureira, Ana Raquel; Campos, Débora A.; Fonte, Pedro; Nunes, Sara; Reis, Flávio; Gomes, Ana Maria; Sarmento, Bruno; Pintado, Maria Manuela. "Characterization of solid lipid nanoparticles produced with carnauba wax for rosmarinic acid oral delivery". RSC Advances 5 29 (2015): 22665-22673. http://dx.doi.org/10.1039/c4ra15802d.
    Published • 10.1039/c4ra15802d
  92. Sereno, J.; Vala, H.; Nunes, S.; Rocha-Pereira, P.; Carvalho, E.; Alves, R.; Teixeira, F.; Reis, F.. "Cyclosporine a-induced nephrotoxicity is ameliorated by dose reduction and conversion to sirolimus in the rat". Journal of Physiology and Pharmacology 66 2 (2015): 285-299. http://www.scopus.com/inward/record.url?eid=2-s2.0-84927565139&partnerID=MN8TOARS.
  93. Santos-Martins, M; Sameiro-Faria, M; Ribeiro, S; Nascimento, H; Reis, F; Miranda, V; Quintanilha, A; et al. "TLR4 and TLR9 polymorphisms effect on inflammation response in end-stage renal disease patients". European Journal of Inflammation 12 3 (2015): 521-529.
    Published
  94. Costa E; Fernandes J; Ribeiro S; Sereno J; Garrido P; Rocha-Pereira P; Coimbra S; et al. "Aging is Associated with Impaired Renal Function, INF-gamma Induced Inflammation and with Alterations in Iron Regulatory Proteins Gene Expression.". (2014): http://europepmc.org/abstract/med/25489488.
    10.14366/AD.2014.0500356
  95. Castro AL; Dias M; Reis F; Teixeira HM. "Gamma-hydroxybutyric acid endogenous production and post-mortem behaviour - the importance of different biological matrices, cut-off reference values, sample collection and storage conditions.". (2014): http://europepmc.org/abstract/med/25287794.
    10.1016/j.jflm.2014.07.008
  96. Gonçalves A; Marques C; Leal E; Ribeiro CF; Reis F; Ambrósio AF; Fernandes R. "Dipeptidyl peptidase-IV inhibition prevents blood-retinal barrier breakdown, inflammation and neuronal cell death in the retina of type 1 diabetic rats.". (2014): http://europepmc.org/abstract/med/24769045.
    10.1016/j.bbadis.2014.04.013
  97. Lopes PC; Fuhrmann A; Carvalho F; Sereno J; Santos MR; Pereira MJ; Eriksson JW; Reis F; Carvalho E. "Cyclosporine A enhances gluconeogenesis while sirolimus impairs insulin signaling in peripheral tissues after 3 weeks of treatment.". (2014): http://europepmc.org/abstract/med/24960264.
    10.1016/j.bcp.2014.06.014
  98. Lopes PC; Fuhrmann A; Sereno J; Espinoza DO; Pereira MJ; Eriksson JW; Reis F; Carvalho E. "Short and long term in vivo effects of Cyclosporine A and Sirolimus on genes and proteins involved in lipid metabolism in Wistar rats.". (2014): http://europepmc.org/abstract/med/24656168.
    10.1016/j.metabol.2014.02.004
  99. Fuhrmann A; Lopes P; Sereno J; Pedro J; Espinoza DO; Pereira MJ; Reis F; Eriksson JW; Carvalho E. "Molecular mechanisms underlying the effects of cyclosporin A and sirolimus on glucose and lipid metabolism in liver, skeletal muscle and adipose tissue in an in vivo rat model.". (2014): http://europepmc.org/abstract/med/24462915.
    10.1016/j.bcp.2014.01.020
  100. Reis, Flávio. "Remyelination in multiple sclerosis – how close are we?". (2014): https://www.omicsonline.org/open-access/remyelination-in-multiple-sclerosis-how-close-are-we-2155-9562-5-192.php?aid=24044.
    10.4172/2155-9562.1000192
  101. Martins F; Catarino C; Rocha-Pereira P; Reis F; Sameiro-Faria M; Miranda V; Belo L; et al. "Haptoglobin 2-2 phenotype is associated with decreased serum iron levels in endstage renal disease patients resistant to rhEPO therapy.". (2014): http://europepmc.org/abstract/med/24974683.
  102. Mega C; Vala H; Rodrigues-Santos P; Oliveira J; Teixeira F; Fernandes R; Reis F; de Lemos ET. "Sitagliptin prevents aggravation of endocrine and exocrine pancreatic damage in the Zucker Diabetic Fatty rat - focus on amelioration of metabolic profile and tissue cytoprotective properties.". (2014): http://europepmc.org/abstract/med/24650557.
    10.1186/1758-5996-6-42
  103. Marques C; Mega C; Gonçalves A; Rodrigues-Santos P; Teixeira-Lemos E; Teixeira F; Fontes-Ribeiro C; Reis F; Fernandes R. "Sitagliptin prevents inflammation and apoptotic cell death in the kidney of type 2 diabetic animals.". (2014): http://europepmc.org/abstract/med/24817793.
    10.1155/2014/538737
  104. Sereno J; Nunes S; Rodrigues-Santos P; Vala H; Rocha-Pereira P; Fernandes J; Santos-Silva A; Teixeira F; Reis F. "Conversion to sirolimus ameliorates cyclosporine-induced nephropathy in the rat: focus on serum, urine, gene, and protein renal expression biomarkers.". (2014): http://europepmc.org/abstract/med/24971338.
    10.1155/2014/576929
  105. Sereno J; Rodrigues-Santos P; Vala H; Rocha-Pereira P; Alves R; Fernandes J; Santos-Silva A; et al. "Transition from cyclosporine-induced renal dysfunction to nephrotoxicity in an in vivo rat model.". (2014): http://europepmc.org/abstract/med/24853130.
    10.3390/ijms15058979
  106. do Sameiro-Faria M; Kohlova M; Ribeiro S; Rocha-Pereira P; Teixeira L; Nascimento H; Reis F; et al. "Potential cardiovascular risk protection of bilirubin in end-stage renal disease patients under hemodialysis.". (2014): http://europepmc.org/abstract/med/25276769.
    10.1155/2014/175286
  107. Fernandes JC; Garrido P; Ribeiro S; Rocha-Pereira P; Bronze-da-Rocha E; Belo L; Costa E; Reis F; Santos-Silva A. "Iron as the key modulator of hepcidin expression in erythroid antibody-mediated hypoplasia.". (2014): http://europepmc.org/abstract/med/25580431.
    10.1155/2014/421304
  108. Martins, F.; Catarino, C.; Rocha-Pereira, P.; Reis, F.; Sameiro-Faria, M.; Miranda, V.; Belo, L.; et al. "Haptoglobin 2-2 phenotype is associated with decreased serum iron levels in endstage renal disease patients resistant to rhEPO therapy". British Journal of Biomedical Science 71 2 (2014): 79-85. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906561873&partnerID=MN8TOARS.
    10.1080/09674845.2014.11669969
  109. Kohlova M; Ribeiro S; do Sameiro-Faria M; Rocha-Pereira P; Fernandes J; Reis F; Miranda V; et al. "Circulating cell-free DNA levels in hemodialysis patients and its association with inflammation, iron metabolism, and rhEPO doses.". (2013): http://europepmc.org/abstract/med/23679088.
    10.1111/hdi.12055
  110. do Sameiro Faria M; Ribeiro S; Rocha-Pereira P; Miranda V; Quintanilha A; Reis F; Costa E; Belo L; Santos-Silva A. "Vascular access versus the effect of statins on inflammation and fibrinolysis in renal dialysis patients.". (2013): http://europepmc.org/abstract/med/23661140.
    10.5301/jva.5000132
  111. Reis, Flávio. "Different pathways and biomarkers of acute and chronic cyclosporine-induced nephrotoxicity in a rat model – focus on overexpression of mTOR and Mki67.". Port J Nephrol Hypert (2013):
  112. Sereno, J.; Parada, B.; Rodrigues-Santos, P.; Lopes, P.C.; Carvalho, E.; Vala, H.; Teixeira-Lemos, E.; et al. "Serum and renal tissue markers of nephropathy in rats under immunosuppressive therapy: Cyclosporine versus sirolimus". Transplantation Proceedings 45 3 (2013): 1149-1156. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876882818&partnerID=MN8TOARS.
    10.1016/j.transproceed.2013.02.085
  113. Nunes, S.; Soares, E.; Fernandes, J.; Viana, S.; Carvalho, E.; Pereira, F.C.; Reis, F.. "Early cardiac changes in a rat model of prediabetes: Brain natriuretic peptide overexpression seems to be the best marker". Cardiovascular Diabetology 12 1 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84874618884&partnerID=MN8TOARS.
    10.1186/1475-2840-12-44
  114. Lopes, P.; Fuhrmann, A.; Sereno, J.; Pereira, M.J.; Nunes, P.; Pedro, J.; Melão, A.; Reis, F.; Carvalho, E.. "Effects of cyclosporine and sirolimus on insulin-stimulated glucose transport and glucose tolerance in a rat model". Transplantation Proceedings 45 3 (2013): 1142-1148. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876870991&partnerID=MN8TOARS.
    10.1016/j.transproceed.2013.02.009
  115. Mascarenhas-Melo, F.; Sereno, J.; Teixeira-Lemos, E.; Marado, D.; Palavra, F.; Pinto, R.; Rocha-Pereira, P.; Teixeira, F.; Reis, F.. "Implication of low HDL-c levels in patients with average LDL-c levels: A focus on oxidized LDL, large HDL subpopulation, and adiponectin". Mediators of Inflammation 2013 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84887385092&partnerID=MN8TOARS.
    10.1155/2013/612038
  116. Mascarenhas-Melo, F.; Palavra, F.; Marado, D.; Sereno, J.; Teixeira-Lemos, E.; Freitas, I.; Isabel-Mendonça, M.; et al. "Emergent biomarkers of residual cardiovascular risk in patients with low HDL-c and/or high triglycerides and average LDL-c concentrations: Focus on HDL subpopulations, oxidized LDL, adiponectin, and uric acid". The Scientific World Journal 2013 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84888877710&partnerID=MN8TOARS.
    10.1155/2013/387849
  117. Parada, B.; Reis, F.; Cerejo, R.; Garrido, P.; Sereno, J.; Xavier-Cunha, M.; Neto, P.; et al. "Omega-3 fatty acids inhibit tumor growth in a rat model of bladder cancer". BioMed Research International 2013 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84880164934&partnerID=MN8TOARS.
    10.1155/2013/368178
  118. Mascarenhas-Melo, F.; Sereno, J.; Teixeira-Lemos, E.; Ribeiro, S.; Rocha-Pereira, P.; Cotterill, E.; Teixeira, F.; Reis, F.. "Markers of increased cardiovascular risk in postmenopausal women: Focus on oxidized-LDL and HDL subpopulations". Disease Markers 35 2 (2013): 19-30. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882302842&partnerID=MN8TOARS.
    10.1155/2013/724706
  119. Mascarenhas-Melo, F.; Marado, D.; Palavra, F.; Sereno, J.; Coelho, T.; Pinto, R.; Teixeira-Lemos, E.; Teixeira, F.; Reis, F.. "Diabetes abrogates sex differences and aggravates cardiometabolic risk in postmenopausal women". Cardiovascular Diabetology 12 1 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84875878475&partnerID=MN8TOARS.
    10.1186/1475-2840-12-61
  120. Palavra, F.; Marado, D.; Mascarenhas-Melo, F.; Sereno, J.; Teixeira-Lemos, E.; Nunes, C.C.; Gonçalves, G.; Teixeira, F.; Reis, F.. "New markers of early cardiovascular risk in multiple sclerosis patients: Oxidized-LDL correlates with clinical staging". Disease Markers 34 5 (2013): 341-348. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878866094&partnerID=MN8TOARS.
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  180. Reis, F.; Campos, M.V.; Bastos, M.; Almeida, L.; Lourenço, M.; Ferrer-Antunes, C.A.; Palmeiro, A.; et al. "Platelet hyperactivation in maintained growth hormone-deficient childhood patients after therapy withdrawal as a putative earlier marker of increased cardiovascular risk". Journal of Clinical Endocrinology and Metabolism 90 1 (2005): 98-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-19944427824&partnerID=MN8TOARS.
    10.1210/jc.2004-0477
  181. Teixeira HM; Reis F; Proença P; Ramos P; Quintela O; López-Rivadulla M; Marques E; Vieira DN. "Vitreous humour as a complementary sample to blood for the detection/confirmation of diazepam: ante-mortem and post-mortem studies in an animal model.". (2004): http://europepmc.org/abstract/med/15688985.
    10.1191/0960327104ht490oa
  182. Santiago, M.; Reis, F.; Almeida, L.; Alcobia, T.; Dionísio, J.; Teixeira, F.. "Impairment of vascular and platelet levels of nitric oxide and cyclic guanosine-',5'-monophosphate in cyclosporin A-induced hypertensive rats". Fundamental and Clinical Pharmacology 17 1 (2003): 43-50. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037326672&partnerID=MN8TOARS.
    10.1046/j.1472-8206.2003.00116.x
  183. Reis, F.; Almeida, L.; Alcobia, T.; Santos-Dias, J.D.; Lourenço, M.; Palmeiro, A.; Ferrer-Antunes, C.A.; et al. "Isosorbide-5-mononitrate treatment prevents cyclosporin A-induced platelet hyperactivation and the underlying nitric oxide-cyclic guanosine-3', 5'-monophosphate disturbances". Thrombosis Research 110 2-3 (2003): 107-115. http://www.scopus.com/inward/record.url?eid=2-s2.0-10744223826&partnerID=MN8TOARS.
    10.1016/S0049-3848(03)00311-6
  184. Reis, F.; Hermida, R.C.; Souza, I.; Maldonado, J.; Tavares, P.; Fontes-Ribeiro, C.A.; Teixeira, H.M.; et al. "Circadian and seasonal variation of endogenous ubiquinone plasma level". Chronobiology International 19 3 (2002): 599-614. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035989775&partnerID=MN8TOARS.
    10.1081/CBI-120004544
  185. Tavares, P.; Reis, F.; Fontes Ribeiro, C.A.; Teixeira, F.. "Cardiovascular effects of cyclosporin treatment in an experimental model | Efeitos cardiovasculares da ciclosporina num modelo experimental". Revista Portuguesa de Cardiologia 21 2 (2002): 141-155. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036129786&partnerID=MN8TOARS.
  186. Reis, F.; Tavares, P.; Rito, L.C.; Teixeira, H.M.; Santos Dias, J.D.; Ferrer-Antunes, C.; Mesquita, J.F.; Teixeira, F.. "Platelet activation is increased in cyclosporin A-induced hypertensive rats". Journal of Cardiovascular Pharmacology 36 1 (2000): 56-64. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033937676&partnerID=MN8TOARS.
  187. Reis, F.; Tavares, P.; Teixeira, F.. "The distribution of catecholamines between plasma and platelets in cyclosporin A-induced hypertensive rats". Pharmacological Research 41 2 (2000): 129-135. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033839925&partnerID=MN8TOARS.
    10.1006/phrs.1999.0572
  188. Reis, F.; Tavares, P.; Ribeiro, C.A.F.; Antunes, F.; Teixeira, F.. "The peripheral serotonergic system and platelet aggregation in cyclosporin A-induced hypertensive rats". Thrombosis Research 96 5 (1999): 365-372. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032762622&partnerID=MN8TOARS.
    10.1016/S0049-3848(99)00115-2
Preface / Postscript
  1. Costa, E; Reis, F; Santos-Silva, A. "Erythropoietic Stimulating Agents". U.A.E.: Bentham Science Publisher. 2013.
    Published
Thesis / Dissertation
  1. Reis, Flávio. "VASCULAR AND PLATELETARY MECHANISMS IN ARTERIAL HYPERTENSION INDUCED BY CYCLOSPORIN A: PREVENTION WITH A NO DONOR - ISOSSORBIDE 5-MONONITRATE". PhD, 2006.
  2. Reis, Flávio. "EFFECTS OF CYCLOSPORIN A ON PLATELET REACTIVITY IN AN EXPERIMENTAL ANIMAL MODEL". Master, 2000.

Intellectual property

Patent
  1. Reis, Flávio; Sofia Domingues Viana. 2024. "SEMI-SOLID FORMULATION FOR VOLUNTARY ORAL ADMINISTRATION OF BIOACTIVE COMPOUNDS TO RODENTS (116301)".
    Granted/Issued

Other

Annotation
  1. Rosendo-Silva, D; Lopes, E; Monteiro-Alfredo, T; Falcao-Pires, I; Eickhoff, H; Viana, S; Reis, F; et al. 2025. "The adipose tissue melanocortin 3 receptor is targeted by ghrelin and leptin and may be a therapeutic target in obesity (vol 594, 112367, 2024)".
    10.1016/j.mce.2024.112410
Other output
  1. TLR4 AND TLR9 POLYMORPHISMS EFFECT ON INFLAMMATORY RESPONSE IN END-STAGE RENAL DISEASE PATIENTS. 2014. Santos Martins, M; Sameiro Faria, M; Ribeiro, S; Rocha Pereira, P; Nascimento, H; Reis, F; Miranda, V; et al.
Spin-off company
  1. 2023. RDefine. Investigação e Desenvolvimento dirigida à melhoria da área preclinica com animais e ao green.
Activities

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2023 - Current Inflammatory biomarkers in diabetic and non-diabetic renal patients on hemodialysis
Co-supervisor
Mestrado Integrado em Medicina (Master)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2022 - Current The role of gut microbiome in the senolytic activity of natural compounds explored for prevention of age-related intestinal inflammation. FCT Grant: 2021.08431.BD
Co-supervisor of Célia Maria da Silva Freitas Costa
Universidade Católica Portuguesa Centro de Investigação em Ciência e Tecnologia das Artes, Portugal
2022 - Current A deep insight in obesity-associated human adipose tissue dysfunction: identifying new microbial and molecular markers for novel therapeutic approaches. FCT Grant: 2021.08160.BD.
Co-supervisor of Daniela Rosendo da Silva
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas (PhD)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2022 - Current Blueberry leaf biomass: a nutraceutical for Multiple Sclerosis¿ relief by targeting the gut-immune-CNS axis. FCT Grant: 2021.05312.BD
Supervisor of Ana Carolina Marques Ferreira
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas (PhD)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2021 - Current The influence of renin-angiotensin system (ras) in pets diabetic dysmotility. FCT Grant : FCT: SFRH/BD/06502/2020
Co-supervisor of Marisa Manuela Esteves Monteiro
Doutoramento em Ciências Veterinárias (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 - Current Beneficial effects of Faecalibacterium prausnitzii and Akkermansia muciniphila delivery systems in inflammatory bowel disease and prediabetes rodent models FCT Grant: SFRH/BD/09481/2020
Supervisor of André Filipe Baltazar Alves
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas (PhD)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2021 - Current A voluntary semi-solid PILL approach for rodent drug dosing - 3R's in motion. FCT Grant: SFRH/BD/08560/2020
Supervisor of Inês Mendes Preguiça
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas (PhD)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2019 - Current New biomarkers for chronic kidney disease management
Co-supervisor of Irina Filipa Lima Lousa
Doutoramento em Ciências Farmacêuticas, ramo de especialização em Bioquímica (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2019 - Current Modeling of pulmonary metastases from osteosarcoma in mice
Co-supervisor of Nuno Renato Amorim de Lima
Master in Experimental Pathology (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2018 - Current Impact of a multidisciplinary approach in clinical research on the cardiovascular prognosis and quality of life of patients
Co-supervisor of Carla Daniela Soares Pais
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2017 - Current Sirtuin 2 as a new target to revert metabolic dysfunction. FCT Grant: SFRH/BD/121923/2016
Co-supervisor of Helena Maria da Silva Leal
Doutoramento em Ciências Farmacêuticas (PhD)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2015 - Current Crosstalk between gut microbiota and metabolic dysregulation in prediabetes – Impact of nutraceutical and therapeutic approaches
Supervisor of Sara Raquel Ramalho Pereira Nunes
Doutoramento em Ciências Farmacêuticas (PhD)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2011 - Current Neuropeptide Y, Y1 receptor and dipeptidyl-peptidase 4: study of the interactions promoting remyelination in an animal model of multiple sclerosis
Supervisor of Filipe Manuel Farto Palavra
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2023 - 2026 Bioconversion of blueberry-based agrowastes into functional ingredients with improved immunonutritional value in Chronic Kidney Disease
Co-supervisor
Programa de doutoramento em ciencias biomédicas (PhD)
Universidade de Coimbra, Portugal
2023 - 2024 Preclinical evaluation of the nutraceutical potential of blueberry-based antioxidant fiber in experimental multiple sclerosis
Co-supervisor
Mestrado em Farmácia, especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023 - 2024 Flavonoids-AhR pharmacodynamics in the gut-immune-kidney axis: therapeutic insights in chronic kidney disease
Co-supervisor
Mestrado em Farmácia, especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023 - 2024 Polyphenols duplibiotic role in Intestinal Inflammatory Disease: focus on next-generation Akkermansia muciniphila
Supervisor
Mestrado em Farmácia, especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023 - 2024 Remyelination potential of sitagliptin, a DPP-4 inhibitor, in Multiple Sclerosis: a preclinical approach
Co-supervisor
Mestrado em Farmácia, especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023 - 2024 Literacia em saúde na área da polimedicação no idoso – Cocriação de conteúdos no âmbito de um projeto europeu
Supervisor
Mestrado em Farmácia, especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2023 - 2024 -food interactions of cholesterol-lowering Statins and Mediterranean-based dietary supplements: friends or foes?
Co-supervisor
Mestrado em Farmácia, especialização em Farmacoterapia Aplicada (Master)
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2021 - 2021 Propriedades antiaterogénicas de polifenóis de oliveira e do azeite - Estudo experimental em modelo animal
Supervisor of Beatriz Maria Lemos Ormonde
Mestrado em Bioquímica (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021 - 2021 Preclinical evaluation of the therapeutic potential of Vaccinium corymbosum L. (blueberry) leaf biomass in experimental Multiple Sclerosis
Co-supervisor of Ana Carolina Marques Ferreira
Mestrado em Investigação Biomédica (Master)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2019 - 2020 Renal effects of blueberry juice in a prediabetic rat model induced by hypercaloric diet
Supervisor of Adelaide Catarina Campos Barbosa
Master in Biomedical Research (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2019 - 2020 Blueberries effects on diet-induced prediabetic nephropathy – an in vivo experimental approach
Co-supervisor
Mestrado em Química Medicinal (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018 - 2019 Effect of doxorubicin in the treatment of osteosarcoma in mice
Co-supervisor of Francisca De Brito Ferreira Pinho Pinheiro
Degree in Veterinary Nursing (Degree)
Instituto Politécnico de Portalegre, Portugal
2017 - 2019 Post-doc Supervision - Projecto HEALTHYAGING 2020 (CENTRO-01-0145-FEDER-000012)
Co-supervisor of Steve Mendes Catarino
Universidade de Coimbra Faculdade de Medicina, Portugal
2018 - 2018 Effects of incretin-based therapies on the gastrointestinal motility of an animal model of Multiple Sclerosis
Co-supervisor of Beatriz de Oliveira Martins
Master in Applied Pharmacology (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018 - 2018 Effects of blueberry juice on the evolution of liver dysfunction in an animal model of pre-diabetes
Supervisor of Ana Catarina Oliveira Castela
Master in Biochemistry (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017 - 2018 Post-doc Supervision - Projecto HEALTHYAGING 2020 (CENTRO-01-0145-FEDER-000012)
Supervisor of Sofia Andreia Domingues Viana
Universidade de Coimbra Faculdade de Medicina, Portugal
2017 - 2017 Early remyelination in the murine model exposed to cuprizone: are there any behavioral alterations?
Co-supervisor of João Paulo Pires Dinis
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015 - 2016 Characterization of an animal model of multiple sclerosis - behavioral and biochemical aspects of cuprizone poisoning
Supervisor of Sara Carolina Henriques
Master in Biochemistry (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015 - 2016 The incretin system ABC’s in health and disease – Novel approaches for obesity and diabetes treatment
Co-supervisor of Ana Luísa Vieira da Natividade Faria João
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2016 Determination of gamma-hydroxybutyric acid (GHB) in blood, urine and hair by GC/MS/MS - Assessment of endogenous and exogenous levels and their application in the areas of Forensic Clinic and Pathology
Co-supervisor of André Alexandre Lobo Lopes de Castro
Doutoramento em Ciências Forenses (PhD)
Faculdade de Medicina da Universidade do Porto , Portugal
2011 - 2016 Natural Killer cell-based immunotherapy: a new approach for targeting CSCs in bladder cancer
Co-supervisor of Ana Margarida Ferreira Teixeira
Doutoramento em Ciências da Saúde, ramo de Ciências Biomédicas
Universidade de Coimbra Faculdade de Medicina, Portugal
2011 - 2016 Anemia and high therapeutic doses of recombinant human erythropoietin in chronic kidney disease – a linkage of risk?
Co-supervisor of Sandra Patrícia Nunes Ribeiro
Doutoramento em Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2015 Post-doc Supervision - Regulation of erythropoietin gene expression in non-renal tissues
Co-supervisor of João Carlos Azevedo Cruz Gonçalves Fernandes
Universidade de Coimbra Faculdade de Medicina, Portugal
2014 - 2015 Characterization of an animal model of prediabetes
Supervisor of Ana Catarina Oliveira Castela
Degree in Biotechnology (Degree)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2014 - 2015 Effects of regular and moderate exercise in a prediabetes model
Supervisor of Sofia Alexandra Gomes Anastácio
Degree in Biotechnology (Degree)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2014 - 2014 Effects of sitagliptin therapy on the evolution of pancreatic and renal lesions in type 2 diabetes - experimental study in the Zucker Diabetic Fatty rat
Supervisor of Ana Cristina Pais Mega de Andrade
Ciências da Saúde (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Post-doc Supervision - Relationship between chronic renal failure, inflammation and erythropoiesis in resistance to human recombinant erythropoietin therapy
Supervisor of João Carlos Azevedo Cruz Gonçalves Fernandes
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Study of the regulation of the inflammatory response and endoplasmic reticulum stress by sitagliptin in the kidney of animals with type 2 diabetes
Co-supervisor of Catarina Isabel Rodrigues Marques
Master in Biochemistry (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012 - 2013 Characterization of risk factors for cardiovascular disease, in pre-diabetics and diabetics, in a population sample from Cova da Beira
Supervisor of Diana Inês Mota Gaspar
Master in Biochemistry (Master)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2012 - 2013 Conversion from cyclosporine to sirolimus in kidney transplantation - Is there renoprotection?
Supervisor of Tiago João Neves Carvalho
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Role of hepcidin impairment in chronic kidney disease - implication for new therapeutics opportunities
Supervisor of António Miguel Ferrão Silveira
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Renoprotective effects of direct renin inhibitors
Supervisor of Joana Marques Martins Cardoso Silva
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2012 - 2013 Response to rhEPO therapy in situations of chronic versus severe renal failure in an experimental animal model
Supervisor of Joana Sanches Pires
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2011 - 2012 Study of the prevalence of pre-diabetes and diabetes in a population sample from Cova da Beira. Characterization of risk factors
Supervisor of Mariana Sofia Lambelho Elvas
Master in Biochemistry (Master)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2011 - 2012 Effects of Ciclosporin-A and Sirolimus on rat aorta vascular smooth muscle cells (A7R5)
Co-supervisor of Diogo António Gonçalves Candeias da Guerra Maio
Master in Biochemistry (Master)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2011 - 2012 Evaluation of the effect of ketamine and isoflurane in the long and medium term in animal models
Supervisor of Laíse Figueiredo de Oliveira
Master in Public Health (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2011 - 2012 Early cardiac effects of a high-sucrose diet in a rat model of prediabetes
Supervisor of Sara Raquel Nunes
Master in Biochemistry (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011 - 2012 Sucrose-induced memory deficits
Co-supervisor of Edna Filipa Pais Soares
Master in Biochemistry (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011 - 2012 Cardiorenal anemia syndrome in the elderly - cytoprotective effects of erythropoietin
Supervisor of Paula Cristina Cruz Correia
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2011 Preventive effect of omega-3 in the treatment of bladder carcinoma
Supervisor of Raquel Sacramento Rosa Cerejo
Master in Biochemistry (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010 - 2011 Cardio-renal effects of immunomodulatory therapy
Supervisor of Ana Marta Romão
Master in Biochemistry (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010 - 2011 Influence of genotype vs. paraoxonase 1 phenotype at risk of cardiovascular disease
Supervisor of José Luis Lemos de Sá
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2011 Pleiotropic effects of statistics and their interactions with anticoagulants and platelet antiaggregants
Supervisor of Filipe Miguel Pereira Viera
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2011 Recombinant human erythropoietin - therapeutic applications and illegal use in sport
Supervisor of Maria João Lobato Cortesão Nobre
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2011 New and old vitamin D analogs as renoprotective therapy
Supervisor of Rui Manuel Andrade Maia Tavares Moreira
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2010 Resistance to recombinant human erythropoietin therapy - studies in experimental models of anemia and chronic kidney disease.
Supervisor of Ana Patrícia Amieiro Garrido
Ciências da Saúde (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2010 - 2010 Minimization of cyclosporine A-induced nephrotoxicity through sirolimus conversion protocols - Mechanisms and biomarkers in an animal model in rat
Supervisor of José Vítor de Oliveira Sereno
Ciências da Saúde (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2010 The role of dexmedetomidine in anesthesia and intensive care
Supervisor of Joana Isabel Afonso Coelho de Oliveira
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2010 Cardio-renal effects of recombinant human erythropoietin (rhEPO) therapy in an animal model of chronic renal failure induced by nephrectomy
Supervisor of Ana Margarida Teixeira
Master in Biochemistry (Master)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2010 Pleiotropic effects of statins - Why the use of high doses of statins in post-myocardial infarction
Supervisor of Filipe Torres Bento Sousa
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2010 Role of inflammation in tumor development: therapeutic potential of COX2 inhibitors
Supervisor of Daniel Luis Sebastião Costa
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2010 Epidemiological study of a sample of the Portuguese population (municipality of Manteigas) - risk factors and non-pharmacological and drug therapy
Supervisor of Luís Filipe Vicente Saraiva
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2010 The use of statins in antineoplastic therapy - current context and future perspectives
Supervisor of Hugo Miguel Moreira Aleixo
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2010 The role of non-pharmacological therapy in the treatment of type 2 diabetes mellitus
Supervisor of Luís Miguel Dos Santos Vieira
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009 - 2009 High density lipoprotein dysfunction and cardiometabolic risk - Relationship with other biomarkers
Supervisor of Filipa Alexandra Mascarenhas Melo
Ciências Biomédicas (PhD)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 Cardiovascular effects of intravenous anesthetics - current concerns and future perspectives
Supervisor of Cláudia Raquel Marques Carreira
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 Endocannabinoid system and cardiovascular therapy: new perspectives
Supervisor of Pedro Miguel Oliveira Pinto Da Cunha
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 Bladder carcinoma in an experimental animal model - Preventive / curative effect of a statin
Supervisor of Ângela Filipa Fonseca Pinto
Master in Biochemistry (Master)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2008 - 2009 Effect of sitagliptin in an animal model of type 2 diabetes mellitus - dysmetabolism, oxidative stress and inflammation
Supervisor of Liliana Figueiredo Ferreira
Master in Biochemistry (Master)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2008 - 2009 Bladder carcinoma - new pharmacological therapies for prevention and treatment
Supervisor of Romeu Joel Fernandes Pinho
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 Type 2 diabetes therapy with incretins
Supervisor of Ricardo Godinho de Andrade
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 The cardio-renal anemia syndrome - pathophysiological bases and therapeutic perspectives of human recombinant erythropoietin
Supervisor of Bruno Miguel dos Santos Pedro
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 Cardiovascular effects of immunosuppressive therapy
Supervisor of Luís Filipe Pedro Moisão França
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 HDL as a target for therapeutic action in dyslipidemia
Supervisor of Ricardo da Silva Vicente
Integrated Master in Medicine (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2008 - 2009 Cardiometabolic effects of using rhEPO in an experimental doping model in sport.
Supervisor of Nuno Miguel Torres Piloto de Albuquerque
Master in Forensic Medicine and Forensic Sciences (Master)
Universidade de Coimbra Faculdade de Medicina, Portugal
2007 - 2008 Characterization of an animal model of renal failure - Evaluation of the effects of rhEPO treatment
Supervisor of Ana Patrícia Amieiro Garrido
Master in Biochemistry (Master)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2007 - 2008 Characterization of an animal model (wistar rat) of bladder carcinoma - Study of Celecoxib (Celebrex)
Supervisor of José Vitor Oliveira Sereno
Degree in Biochemistry (Degree)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2006 - 2007 Characterization of an Animal Model (Wistar rat) of bladder carcinoma - Sirolimus Study
Supervisor of André Tiago Ribeiro Dias
Degree in Biochemistry (Degree)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2005 - 2006 Study of the influence of aerobic exercise in Zucker Diabetty Fatty rats
Supervisor of Ana Patrícia Amieiro Garrido
Degree in Biochemistry (Degree)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2004 - 2005 Physical exercise and cardiovascular risk - comparative study of the effects of running and swimming
Supervisor of Nuno Miguel Torres Piloto de Albuquerque
Degree in Biochemistry (Degree)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2004 - 2005 Effect of physical exercise on an animal model of type 2 diabetes
Supervisor of Ana Sofia Simões Bento Baptista
Degree in Biochemistry (Degree)
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2002 - 2003 The peripheral serotonergic system and the thromboxane A2 / prostacyclin pathway in rats submitted to isosorbide 5-mononitrate to treat cyclosporine A-induced hypertension
Supervisor of Luísa Margarida da Silva Ponte
Degree in Biochemistry (Degree)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2002 - 2003 Effect of Isosorbide 5-mononitrate on plasma and platelet contents of catecholamines in rats with cyclosporine A-induced hypertension
Supervisor of Luís Gabriel Borges Rocha
Degree in Biochemistry (Degree)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2021 - Current Week of round table related to the theme "World Food Day" (2021)
Other (Co-organisor)
2024/01/25 - 2024/01/26 V SPCAL Congress (Sociedade Portuguesa de Ciências em Animais de Laboratório | Portuguese Society of Laboratory Animal Sciences) (2024/01/25 - 2024/01/26)
Congress (President of the Organising Committee)
Sociedade Portuguesa de Ciências em Animais de Laboratório, Portugal
2023/02/01 - 2023/02/03 53rd Annual Meeting of the Portuguese Society of Pharmacology, 41st Clinical Pharmacology Meeting and 22nd Toxicology Meeting (2023/02/01 - 2023/02/03)
Congress (President of the Organising Committee)
Sociedade Portuguesa de Farmacologia, Portugal
2021/12/10 - 2021/12/10 1st SPCAL Scientific Day – Responsible Research and Innovation in Laboratory Animal Sciences (2021/12/10 - 2021/12/10)
Congress (Member of the Organising Committee)
Sociedade Portuguesa de Ciências em Animais de Laboratório, Portugal
2019/10/03 - 2019/10/04 Curso CRISH – Cocriação de soluções inovadoras para a saúde (2019/10/03 - 2019/10/04)
Other (President of the Organising Committee)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2018/11/15 - 2018/11/15 3rd National Symposium on Animal Welfare Bodies (AWBs)– “3Rs in action” (2018/11/15 - 2018/11/15)
Symposium (President of the Organising Committee)
FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2017/02/02 - 2017/02/04 XLVII Annual Meeting of the Portuguese Society of Pharmacology, XXVI Clinical Pharmacology Meeting and XVII Toxicology Meeting (2017/02/02 - 2017/02/04)
Congress (Member of the Organising Committee)
Sociedade Portuguesa de Farmacologia, Portugal
2012/03/31 - 2012/03/31 Joint Meeting of the Portuguese Society of Hemorheology and Microcirculation and the Vascular Biology Center of the Portuguese Society of Angiology and Vascular Surgery (2012/03/31 - 2012/03/31)
Meeting (President of the Organising Committee)
Sociedade Portuguesa de Hemorreologia e Microcirculação, Portugal
2011/02/02 - 2011/02/04 XLI Annual Meeting of the Portuguese Pharmacology Society XXIX Clinical Pharmacology Meeting and X Toxicology Meeting (2011/02/02 - 2011/02/04)
Congress (Member of the Organising Committee)
Sociedade Portuguesa de Farmacologia, Portugal
2005/11/26 - 2005/11/26 XVI Annual Meeting of the Portuguese Society of Hemorheology and Microcirculation (2005/11/26 - 2005/11/26)
Meeting (Member of the Organising Committee)
Sociedade Portuguesa de Hemorreologia e Microcirculação, Portugal
2003/12/04 - 2003/12/06 XXXIV Annual Meeting of the Portuguese Pharmacology Society (2003/12/04 - 2003/12/06)
Congress (Member of the Organising Committee)
Sociedade Portuguesa de Farmacologia, Portugal

Association member

Society Organization name Role
2022 - Current VICE-PRESIDENT of EXECUTIVE BOARD of Portuguese Society of Pharmacology
2021 - Current MEMBER OF EXECUTIVE BOARD - Portuguese Society of Laboratory Animal Sciences (SPCAL)
2020 - Current VICE-PRESIDENT OF EXECUTIVE BOARD - Portuguese Society of Atherosclerosis
2020 - Current VICE-PRESIDENT of EXECUTIVE BOARD of Portuguese Society of Hemorrheology and Microcirculation
2019 - Current SECRETARY OF GENERAL ASSEMBLY - Portuguese Society of Pharmacology General Assembly (Secretary)
2012 - Current European Federation for the Study Diabetes (EFSD)
2012 - Current European Society of Atherosclerosis (EAS)
2012 - Current European Renal Association - European Dialysis and Transplant Association (ERA-EDTA)
2010 - Current Sociedade Portuguesa de Diabetologia
2008 - Current Sociedade Portuguesa de Ciências em Animais de Laboratório
2000 - Current Sociedade Portuguesa de Hemorreologia e Microcirculação (SPHM) Membro (desde 2000), Direção (desde 2006) e Vice-Presidente (desde 2020)
1998 - Current Sociedade Portuguesa de Farmacologia Membro (desde 1998), Secretário da AG (2019-2022) e Vice-Presidente (2022-2024)
2005 - 2023 Sociedade Portuguesa de Aterosclerose Membro (desde 2005), Direção (2017-2020) e Vice-Presidente (2020-2023)
2006 - 2018 SECRETARY OF EXECUTIVE BOARD of Portuguese Society of Hemorrheology and Microcirculation 2006-2008 | 2012-2014 | 2014-2016 | 2016-2018
2011 - 2013 MEMBER OF FISCAL COUNCIL - Portuguese Society of Atherosclerosis Conselho Fiscal (Vogal)
2008 - 2010 TRESOURER of EXECUTIVE BOARD of Portuguese Society of Hemorrheology and Microcirculation

Committee member

Activity description
Role
Institution / Organization
2019 - Current Doctoral Thesis Monitoring Committee - INTERUNIVERSITY DOCTORAL PROGRAM IN AGING AND CHRONIC DISEASES, a partnership between UC, Universidade Nova de Lisboa and Universidade do Minho.
Member
Universidade do Minho Escola de Medicina, Portugal
2016 - Current Doctoral Monitoring Committee - DOCTORAL PROGRAM IN HEALTH SCIENCES - Faculty of Medicine from University of Coimbra
Member
Universidade de Coimbra Faculdade de Medicina, Portugal
2016 - Current Editorial Board of PORTUGUESE JOURNAL OF NEPHROLOGY AND HYPERTENSION
Member
2011 - Current Editorial Board of ACTA UROLÓGICA PORTUGUESA
Member
2010 - Current Editorial Board of CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
Member
2020 - 2020 Workgroup for the EUROPEAN CERTIFIED PHARMACOLOGIST PROGRAM on behalf of Portuguese Society of Pharmacology
Member
Sociedade Portuguesa de Farmacologia, Portugal
2015 - 2018 Editorial Board of SPRINGER PLUS
Member

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2024 - Current Advanced Course in Tissue Barriers in Health and Disease Doctoral Programme in Health Sciences (Doutoramento) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2023 - Current Advanced Courses "One Health" Doctoral Program in Experimental Biology and Biomedicine (BEB) (Doutoramento) Universidade de Coimbra, Portugal
2022 - Current Hot Topics in Medicine Mestrado em Química Medicinal (Mestrado) Universidade de Coimbra, Portugal
2022 - Current Clinical and Forensic Toxicology Integrated Master's Degree in Medicine (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2022 - Current Toxicity and Disease Master's degree in Cellular and Molecular Biology (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022 - Current Natural Bioactive Compounds Master Degree in Applied Pharmacotherapy (Mestrado) Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2022 - Current “Participatory praxis in healthy aging research: Why and how should we get involved?" European Doctoral School of Aging Eit Health (Doctorat) EIT Health, Germany
2021 - Current Societal Challenges Degree in Biology (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020 - Current Efficacy and Safety of Natural Products Integrated Master's Degree in Medicine (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2020 - Current Biology of Nutrition Integrated Master's Degree in Medicine (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2020 - Current Laboratory Rotations Master degree in Biochemistry (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020 - Current Pharmacology II Master degree in Medicinal Chemistry (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019 - Current Seminars Doctoral Program in Experimental Biology and Biomedicine (BEB) (Doutoramento) Universidade de Coimbra, Portugal
2018 - Current Animal Experimentation Advanced Course Doctoral Program in Health Sciences (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal
2018 - Current Cardiovascular Sciences Advanced Course Doctoral Program in Health Sciences (Doutoramento) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2018 - Current Pharmacology II Degree in Medicinal Chemistry (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017 - Current Research Seminars Integrated Master's Degree in Medicine (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2017 - Current Research Methodologies and Techniques Master in Biomedical Research (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2017 - Current Thematic Seminars Master in Applied Pharmacology (Mestrado) FFUC - Faculdade de Farmácia da Universidade Coimbra, Portugal
2017 - Current Biotoxicology Master Degree in Food Quality and Technology (Mestrado) Instituto Politécnico de Viseu Escola Superior Agrária de Viseu, Portugal
2017 - Current Research Methods and Techniques Advanced Course Doctoral Program in Health Sciences (Doutoramento) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2016 - Current Applied Research Integrated Master's Degree in Medicine (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2016 - Current Laboratory Rotations Master in Biomedical Research (Mestrado integrado) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2007 - 2011 Therapeutics (I and II) Degree in Medicine (Licenciatura) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2007 - 2011 Clinical Pharmacology and Toxicology Degree in Medicine (Licenciatura) FMUC - Faculdade de Medicina da Universidade de Coimbra, Portugal
2007 - 2010 Pharmacology Degree in Health Technologies (Licenciatura) Universidade Católica Portuguesa Escola Superior Politécnica de Saúde Porto, Portugal
2007 - 2010 Quality Control and Pharmacovigilance Degree in Health Technologies (Licenciatura) Universidade Católica Portuguesa Escola Superior Politécnica de Saúde Porto, Portugal

Evaluation committee

Activity description
Role
Institution / Organization Funding entity
2023 - 2023 Invited reviewer to evaluate PhD proposals in 2023 for FCT in the panel of Clinical Medicine and Health Sciences
Member
FCT - Fundação para a Ciência e Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2022 - 2022 Invited Reviewer for Evaluation of proposals for Competitive Funding - Programme NRP 79 (2022) - Swiss National Science Foundation (SNSF) (SWITZERLAND)
Evaluator
Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung, Switzerland Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung
2021 - 2021 Invited Reviewer for Evaluation of proposals for Competitive Funding - Programme Appel à Projets Résilience COVID-19 (2021)- Agence Nationale de la Recherche (ANR) ¿ (FRANCE) Agence nationale de la recherche, France
2020 - 2020 Invited Reviewer for Evaluation of Proposals for Competitive Funding - Programme Clinical Research (KLIF) 2020 - Austrian Science Fund (FWF)
Evaluator
Fonds zur Förderung der wissenschaftlichen Forschung, Austria Fonds zur Förderung der wissenschaftlichen Forschung
2020 - 2020 Invited Reviewer to evaluate reserch proposals of proposals for Competitive Funding - PRIN: Progetti di ricerca di rilevante interesse nazionale ¿ Bando 2020 - Italian Ministry of University and Research (MUR) - (ITALY)
Evaluator
Italian Ministry of University and Research, Italy Italian Ministry of University and Research
2016 - 2016 Invited Reviewer for Evaluation of proposals for Competitive Funding - RD Lawrence Fellowship full application 2016 - Diabetes UK
Evaluator
Diabetes UK
2004 - 2016 Evaluation Committee of the FMUC for the Integrated Performance Evaluation System of Public Administration (SIADAP)
Member
Universidade de Coimbra Faculdade de Medicina, Portugal
2015 - 2015 Invited Reviewer for Evaluation of proposals for Competitive Funding - Programme CE17 2015 - Recherche translationnelle en Santé - Agence Nationale de la Recherche (ANR) – (FRANCE)
Evaluator
Agence nationale de la recherche
2013 - 2013 Invited Reviewer for Evaluation of Proposals for Competitive Funding - Grant Proposal for the 2013 National Research Funding Competition - Superior Council of the National Fund for Scientific & Technological Development – (CHILE)
Evaluator
Superior Council of the National Fund for Scientific & Technological Development – (Chile)
2009 - 2009 Invited Reviewer for Evaluation of Proposals for Competitive Funding - Grant Proposal in Bio-Medical SPA Research 2009 Fondazione per la Ricerca Scientifica Termale (FoRST) (ITALY)
Evaluator
Fondazione per la Ricerca Scientifica Termale (FoRST) – (Italy)

Journal scientific committee

Journal title (ISSN) Publisher
2020 - 2020 Food & Function (2042-650X) The Royal Society of Chemistry
2020 - 2020 EBioMedicine (2352-3964) Elsevier
2017 - 2020 Nutrients (2072-6643) MDPI AG
2019 - 2019 Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (0925-4439) Elsevier
2019 - 2019 Frontiers in Pharmacology (1663-9812) Frontiers Media SA
2019 - 2019 Frontiers in Physiology (1664-042X) Frontiers Media SA
2019 - 2019 Obesity Medicine (2451-8476) Elsevier
2019 - 2019 Oxidative Medicine and Cellular Longevity (1942-0994) Hindawi Limited
2018 - 2019 Oxidative Medicine and Cellular Longevity (1942-0994) Hindawi Limited
2017 - 2019 Brain Behavior and Immunity (1090-2139) Elsevier
2016 - 2019 Revista Portuguesa de Cardiologia (0870-2551) Elsevier
2018 - 2018 Disease Models & Mechanisms (1754-8411) The Company of Biologists
2018 - 2018 Journal of Biological Regulators and Homeostatic Agents
2018 - 2018 Journal of Diabetes Research (2314-6753) Hindawi Limited
2018 - 2018 Life Sciences (0024-3205) Elsevier
2018 - 2018 Neuroscience Letters (0304-3940) Elsevier
2018 - 2018 Phytotherapy Research (1099-1573) Wiley (John Wiley & Sons)
2017 - 2018 Oxidative Medicine and Cellular Longevity (1942-0994) Hindawi Limited
2016 - 2018 Kidney and Blood Pressure Research (1423-0143) S. Karger AG
2015 - 2018 International Journal of Biological Sciences (1449-2288) Ivyspring International Publisher
2014 - 2018 British Journal of Pharmacology (1476-5381) Wiley (Blackwell Publishing)
2017 - 2017 Antioxidants
2017 - 2017 Bioscience Reports (1573-4935) Portland Press
2017 - 2017 Brain Research (0006-8993) Elsevier
2017 - 2017 Brazilian Journal of Pharmaceutical Sciences (1984-8250) SciELO
2017 - 2017 Cellular Physiology and Biochemistry (1421-9778) Cell Physiol Biochem Press GmbH and Co KG
2017 - 2017 Evidence-based Complementary and Alternative Medicine (1741-4288) Hindawi Limited
2017 - 2017 Food and Chemical Toxicology (0278-6915) Elsevier
2017 - 2017 Food Research International (0963-9969) Elsevier
2017 - 2017 Fundamental and Clinical Pharmacology (1472-8206) Wiley (Blackwell Publishing)
2017 - 2017 Heart and Vessels (1615-2573) Springer-Verlag
2017 - 2017 Journal of International Medical Research (1473-2300) SAGE Publications
2017 - 2017 Marine Drugs (1660-3397) MDPI AG
2017 - 2017 Mediators of Inflammation (1466-1861) Hindawi Limited
2017 - 2017 Medicines (2305-6320) MDPI AG
2017 - 2017 Pharmacology
2017 - 2017 Toxicology and Applied Pharmacology (1096-0333) Elsevier
2016 - 2017 Biomedicine & Pharmacotherapy (0753-3322) Elsevier
2016 - 2017 Current Medicinal Chemistry (0929-8673) Bentham Science
2016 - 2017 Scientific Reports (2045-2322) Springer Science and Business Media LLC
2013 - 2017 Obesity Reviews (1467-789X) Wiley (Blackwell Publishing)
2012 - 2017 PLoS ONE (1932-6203) Public Library of Science
2011 - 2017 Cardiovascular Diabetology (1475-2840) Springer (Biomed Central Ltd.)
2010 - 2017 Acta Urológica Portuguesa (2387-0419) Associacao Portuguesa de Urologia
2016 - 2016 Acta Diabetologica (1432-5233) Springer-Verlag
2016 - 2016 Basic & Clinical Pharmacology & Toxicology (1742-7843) Wiley (Blackwell Publishing)
2016 - 2016 Canadian Journal of Physiology and Pharmacology (1205-7541) Canadian Science Publishing
2016 - 2016 Cell Proliferation (1365-2184) Wiley (Blackwell Publishing)
2016 - 2016 Ciência & Saúde Coletiva (1413-8123) SciELO
2016 - 2016 Current Drug Safety (1574-8863) Bentham Science
2016 - 2016 Drug Delivery (1521-0464) Informa UK (Taylor & Francis)
2016 - 2016 European Journal of Inflammation (1721-727X) SAGE Publications
2016 - 2016 Human Psychopharmacology Clinical and Experimental (1099-1077) Wiley (John Wiley & Sons)
2016 - 2016 Journal of Cardiovascular Pharmacology and Therapeutics (1940-4034) SAGE Publications
2016 - 2016 Journal of Science and Medicine in Sport (1440-2440) Elsevier
2016 - 2016 Journal of Vascular Research (1423-0135) S. Karger AG
2016 - 2016 Medical Science Monitor (1643-3750) "International Scientific Information, Inc."
2016 - 2016 Pediatric Research (1530-0447) Springer Science and Business Media LLC
2016 - 2016 Pharmacological Reports (2299-5684) Springer-Verlag
2016 - 2016 Reproductive Biology (1642-431X) Elsevier
2015 - 2016 Journal of Diabetes and its Complications (1056-8727) Elsevier
2015 - 2016 Toxicology
2015 - 2015 African Health Sciences
2015 - 2015 Biomarkers (1366-5804) Informa UK (Taylor & Francis)
2015 - 2015 Boletim da Sociedade Portuguesa de Hemorreologia e Microcirculação
2015 - 2015 Cancer Biomarkers (1875-8592) IOS Press
2015 - 2015 Cell Biology International (1095-8355) Wiley (John Wiley & Sons)
2015 - 2015 Diabetes (0012-1797) American Diabetes Association
2015 - 2015 Drug Development and Industrial Pharmacy (1520-5762) Informa UK (Taylor & Francis)
2015 - 2015 Food Chemistry (0308-8146) Elsevier
2015 - 2015 International Journal of Environmental Research and Public Health (1660-4601) MDPI AG
2015 - 2015 International Journal of Immunopathology and Pharmacology (0394-6320) SAGE Publications
2015 - 2015 Journal of Cellular and Molecular Medicine (1582-4934) Wiley (Blackwell Publishing)
2015 - 2015 Journal of Clinical Medicine
2015 - 2015 Journal of Hematology & Thromboembolic Diseases (2329-8790) OMICS Publishing Group
2015 - 2015 Journal of Physiology and Biochemistry (1877-8755) Springer-Verlag
2015 - 2015 Journal of Applied Toxicology (1099-1263) Wiley (John Wiley & Sons)
2015 - 2015 Journal of Transplantation Technologies & Research (2161-0991) OMICS Publishing Group
2015 - 2015 Leukemia (1476-5551) Springer Science and Business Media LLC
2015 - 2015 Molecular Nutrition & Food Research (1613-4133) Wiley (John Wiley & Sons)
2015 - 2015 Ophthalmic Research (1423-0259) S. Karger AG
2015 - 2015 Pediatric Exercise Science (1543-2920) Human Kinetics
2015 - 2015 Redox Report (1351-0002) Maney Publishing
2015 - 2015 SpringerPlus (2193-1801) Springer (Biomed Central Ltd.)
2014 - 2015 Millenium - Journal of Education Technologies and Health (1647-662X) Instituto Politecnico de Viseu
2013 - 2015 Diabetology & Metabolic Syndrome (1758-5996) Springer (Biomed Central Ltd.)
2012 - 2015 International Journal of Molecular Sciences (1422-0067) MDPI AG
2009 - 2015 Kidney International (1523-1755) Elsevier
2014 - 2014 Aging and Disease (2152-5250) Aging and Disease
2014 - 2014 BioMed Research International (2314-6141) Hindawi Limited
2014 - 2014 Biomedical & Pharmacology Journal (2456-2610) Oriental Scientific Publishing Company
2014 - 2014 Endocrine Metabolic & Immune Disorders - Drug Targets (1871-5303) Bentham Science
2014 - 2014 Expert Review of Endocrinology & Metabolism (1744-8417) Informa UK (Taylor & Francis)
2014 - 2014 Inflammation (1573-2576) Springer-Verlag
2014 - 2014 JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH (0973-709X) JCDR Research and Publications
2014 - 2014 Journal of Separation Science (1615-9314) Wiley (John Wiley & Sons)
2014 - 2014 Korea-Australia Rheology Journal (2093-7660) Springer-Verlag
2014 - 2014 Quality of Life Research (1573-2649) Springer-Verlag
2013 - 2013 Anais da Academia Brasileira de Ciências (0001-3765) SciELO
2013 - 2013 British Journal of Medicine and Medical Research (2231-0614) Sciencedomain International
2013 - 2013 European Journal of Sport Science (1746-1391) Informa UK (Taylor & Francis)
2013 - 2013 Journal of Diabetes & Metabolic Disorders (2251-6581) Springer (Biomed Central Ltd.)
2013 - 2013 Journal of Drug Metabolism & Toxicology (2157-7609) OMICS Publishing Group
2013 - 2013 SAGE Open Medicine (2050-3121) SAGE Publications
2012 - 2013 BMC Nephrology (1471-2369) Springer (Biomed Central Ltd.)
2011 - 2013 Forensic Science International (0379-0738) Elsevier
2010 - 2013 American Journal of Nephrology
2010 - 2013 Clinical and Experimental Pharmacology and Physiology (1440-1681) Wiley (Blackwell Publishing)
2012 - 2012 Annals of Nutrition and Metabolism (1421-9697) S. Karger AG
2012 - 2012 Blood Cells Molecules and Diseases (1096-0961) Elsevier
2012 - 2012 Diabetes and Vascular Disease Research (1752-8984) SAGE Publications
2012 - 2012 Disease Markers (1875-8630) Hindawi Limited
2012 - 2012 Endocrine (1559-0100) Springer-Verlag
2012 - 2012 iConcept Press
2012 - 2012 Journal of Endocrinology (1479-6805) Bioscientifica
2012 - 2012 Journal of Pharmacology and Pharmacotherapeutics (0976-500X) Medknow Publications
2012 - 2012 Molecular and Cellular Biochemistry (1573-4919) Springer-Verlag
2012 - 2012 Molecular and Cellular Endocrinology (0303-7207) Elsevier
2012 - 2012 QJM (1460-2393) Oxford University Press
2012 - 2012 Resuscitation (0300-9572) Elsevier
2012 - 2012 Scandinavian Journal of Urology and Nephrology (1651-2065) Informa UK (Taylor & Francis)
2010 - 2012 Journal of Pharmacy And Bioallied Sciences (0975-7406) Medknow Publications
2008 - 2012 Renal Failure (1525-6049) Informa UK (Taylor & Francis)
2011 - 2011 Blood Purification (1421-9735) S. Karger AG
2011 - 2011 Chronicles of Young Scientists (2229-5186) Medknow Publications
2011 - 2011 Experimental Biology and Medicine (1535-3699) SAGE Publications
2011 - 2011 Journal of Forensic and Legal Medicine (1752-928X) Elsevier
2011 - 2011 Neuropharmacology (0028-3908) Elsevier
2011 - 2011 Obesity Facts (1662-4033) S. Karger AG
2010 - 2011 American Journal of Hypertension (1941-7225) Oxford University Press
2010 - 2011 Hemodialysis International (1542-4758) Wiley (Blackwell Publishing)
2009 - 2011 Nephrology (1440-1797) Wiley (Blackwell Publishing)
2010 - 2010 African Journal of Pharmacy and Pharmacology (1996-0816) Academic Journals
2010 - 2010 British Journal of Cancer (1532-1827) Springer Science and Business Media LLC
2010 - 2010 Journal of Cancer Biology and Therapeutics (2379-5972) Gratis Open Access Publishers LLC
2010 - 2010 International Immunopharmacology (1567-5769) Elsevier
2010 - 2010 Nefrología (0211-6995) Elsevier
2010 - 2010 Pharmacological Research (1096-1186) Elsevier
2010 - 2010 The Tohoku Journal of Experimental Medicine (1349-3329) Tohoku University Medical Press
2009 - 2010 Toxins (2072-6651) MDPI AG
2009 - 2009 Archives of Medical Research (0188-4409) Elsevier
2009 - 2009 Journal of Pancreas
2009 - 2009 Nephrology Dialysis Transplantation (1460-2385) Oxford University Press
2009 - 2009 The Open Drug Discovery Journal (1877-3818) Bentham Science
2008 - 2008 The Open Clinical Chemistry Journal (1874-2416) Bentham Science
2007 - 2008 Transplantation (0041-1337) Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins

Other jury / evaluation

Activity description Institution / Organization
2017 - 2017 Discussion of Seminar I on the Doctoral Thesis Project in Pharmaceutical Sciences, Faculty of Pharmacy, University of Coimbra PhD Student: Helena Maria da Silva Leal Thesis: Sirtuin 2 as a new target to revert metabolic dysfunction Universidade de Coimbra Faculdade de Farmácia, Portugal
2017 - 2017 Discussion of the PhD Thesis Project in Pharmaceutical Sciences, Faculty of Pharmacy, University of Coimbra PhD student: Jorge M. Alves Silva Thesis: An innovative approach to the treatment of pulmonary arterial hypertension using plant extracts encapsulated in extracellular vesicles Universidade de Coimbra Faculdade de Farmácia, Portugal
2013 - 2013 External Evaluator of the Seminar on Doctorate in Medicine and Life Sciences at the Faculty of Medical Sciences - Universidade Nova de Lisboa PhD student: Inês Raquel Claro Aires Thesis: Development of a cellular model for familial renal glucosuria: evaluation of mutants and implications for the treatment of type 2 diabetes mellitus Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Distinctions

Award

2023 Prémio Orlando Leitao - Best oral communication
Sociedade Portuguesa de Neurologia, Portugal
2023 Menção Honrosa do Prémio Pedro Eurico Lisboa - Best paper in diabetes in 2022
Sociedade Portuguesa de Diabetologia, Portugal
2023 Melhor poster em investigação fundamental
Sociedade Portuguesa de Diabetologia, Portugal
2023 Melhor comunicação oral em investigação fundamental
Sociedade Portuguesa de Diabetologia, Portugal
2021 Refinement Prize 2021 - European Partnership for Alternatives to Animal testing (EPAA)
European Partnership for Alternatives to animal testing (EPAA), Belgium
2021 Bolsa Pereira Monteiro de Apoio à Investigação Translacional em Neurologia
Sociedade Portuguesa de Neurologia, Portugal

Other distinction

2022 Travel Grant for participation in the 15th FELASA Congress (2022)
FELASA - Federation of European Laboratory Animal Sciences Associations, Belgium
2022 Projetos de Ignição e Provas de Conceito INOVC+
Comissão de Coordenação e Desenvolvimento Regional do Centro, Portugal

Universidade de Coimbra, Portugal
2020 Travel Grant for participation in the 88th EAS Meeting
European Atherosclerosis Society, Sweden
2019 Travel Grant for participation in the 87th EAS Meeting
European Atherosclerosis Society, Sweden
2018 Bolsa de Investigação - Melhor projecto de investigação na área da Urologia
Associação Portuguesa de Urologia | Jaba Recordati , Portugal
2018 Prémio de Boas Práticas de Envelhecimento Ativo e Saudável - Categoria Conhecimento+ (Edição 2018)
Comissão de Coordenação e Desenvolvimento Regional do Centro, Portugal

Ageing@Coimbra, Portugal
2017 Bolsa Emílio Peres da Sociedade Portuguesa de Diabetologia 2017 – ao melhor projecto de investigação na área da nutrição
Sociedade Portuguesa de Diabetologia, Portugal
2017 Menção Honrosa para comunicação oral apresentada no XXV Congresso Português de Aterosclerose
Sociedade Portuguesa de Aterosclerose, Portugal
2017 Bolsa de Ignição do projeto INOV C 2020
Universidade de Coimbra, Portugal
2017 Top 1% Peer Review Award - Multidisciplinary
PUBLONS, United States
2016 Prémio para melhor projecto de investigação na área da diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2016 Prémio Orlando Leitão/Biogen 2016 - melhor comunicação orais do congresso
Sociedade Portuguesa de Neurologia, Portugal
2015 Travel Grant para participação no FEBS Young Scientists Forum
Federation of European Biochemical Societies, United Kingdom
2015 Prémio Bayer - Melhor comunicação oral apresentada na Reunião de Primavera-Verão do Grupo de Estudos de Esclerose Múltipla
2015 Travel Grant para participação no 4th European Congress of Immunology
European Federation of Immunological Societies, Netherlands
2015 Prémio para melhor comunicação oral na área de Neurosciences and autoimmunity apresentada no UMIB SUMMIT 2015
2015 Menção honrosa para trabalho de investigação no âmbito do Prémio de Investigação Científica Professora Doutora Maria Odette Santos-Ferreira
Ordem dos Farmaceuticos, Portugal
2015 Prémio para melhor apresentação oral “Rapid-fire posters” na área “New techniques in Bioimaging” no VII Meeting Anual do IBILI
2014 One of the Best Abstracts for Young Scientists in the ERa-EDTA Congress 2014 (Amsterdam)
European Renal Association European Dialysis and Transplant Association, Italy
2014 Best poster presentation - XVIII Congress da Sociedade Portuguesa de Bioquímica
Sociedade Portuguesa de Bioquímica, Portugal
2014 Prémio Ana Maria Correia - Melhor projecto de investigação científica na área da transplantação
Sociedade Portuguesa de Transplantação / Associação Portuguesa de Urologia, Portugal
2013 Menção Honrosa para comunicação oral na área da diabetes experimental apresentada na Reunião Anual da Sociedade Portuguesa de Diabetologia 2013
Sociedade Portuguesa de Diabetologia, Portugal
2013 Prémio para projecto de investigação na área da diabetes no âmbito do Grupo de Investigação Fundamental e Translacional (GIFT)
Sociedade Portuguesa de Diabetologia, Portugal
2013 Bolsa para trabalho de investigação - GAI da FMUC
Universidade de Coimbra Faculdade de Medicina, Portugal
2013 Uro-Oncology Grant 2013 - Melhor trabalho na área da uro-oncologia
Astellas European Foundation, United Kingdom
2013 Melhor trabalho de investigação - Congresso Anual da Associação Portuguesa de Urologia
Associação Portuguesa de Urologia, Portugal
2013 Melhor trabalho de investigação - Congresso da Sociedade Portuguesa de Diabetologia
Sociedade Portuguesa de Diabetologia, Portugal
2013 Travel Grant for the 15th International Congress of Immunology
European Federation of Immunological Societies, Netherlands
2012 Best Scientific Oral Presentation - Basic Science
Sociedade Portuguesa de Nefrologia, Portugal
2012 Melhor trabalho em Investigação Básica - Encontro Renal 2012
Sociedade Portuguesa de Nefrologia, Portugal
2012 One of the Best Abstracts presented by young authors at the 49th Congress of ERA-EDTA
European Renal Association European Dialysis and Transplant Association, Italy
2012 Oral presentation Travel Award for the 20th Meeting of the EAU Section of Urological Research, Strasbourg
European Association of Urology, Netherlands
2012 Melhor comunicação oral de “Health Surveillance” apresentada na Conferência CEF 2012
2012 Melhor projecto de investigação na área da Urologia
Associação Portuguesa de Urologia, Portugal
2011 Best Scientific presentation - 5º Congresso Português de Hipertensão
Sociedade Portuguesa de Hipertensão, Portugal
2011 Best research project in diabetes - Congresso Português de Diabetes
Sociedade Portuguesa de Diabetologia, Portugal
2011 Best Scientific Oral Presentation - Basic Science - XII Congresso Português de Endocrinologia
Sociedade Portuguesa de Diabetes, Endocrinologia e Metabolismo, Portugal
2011 Best Original Study in Nephrology - Prémio ROCHE
Sociedade Portuguesa de Nefrologia, Portugal
2011 Best research project in Urology - Congresso da Associação Portuguesa de Urologia
Associação Portuguesa de Urologia, Portugal
2011 Best Scientific presentation - XIX Congresso Nacional de Aterosclerose
Sociedade Portuguesa de Aterosclerose, Portugal
2010 Best Poster with oral presentation - Prémio EDOL
Sociedade Portuguesa de Dermatologia e Venereologia, Portugal
2010 Best Scientific Oral Presentation - XII Congresso Português de Endocrinologia
Sociedade Portuguesa de Diabetes, Endocrinologia e Metabolismo, Portugal
2010 Honorable Mention on Clinical investigation
2010 Best research project in Urology - Reunião Anual da Sociedade Portuguesa de Transplantação
Sociedade Portuguesa de Transplantação / Associação Portuguesa de Urologia, Portugal
2010 Best research project in Multiple Sclerosis
Grupo de Estudos de Esclerose Múltipla | Merck Serono, Portugal
2009 Best scientific work - Pfizer Price in Oncologic Urology
European Organisation for Research and Treatment of Cancer, Belgium
2009 Best Scientific Oral Comunication - 17º Congresso Português de Aterosclerose
Sociedade Portuguesa de Aterosclerose, Portugal
2009 Best research project in Urology - Congresso da Associação Portuguesa de Urologia
Associação Portuguesa de Urologia, Portugal
2008 Best Scientific Oral Comunication - 16º Congresso Português de Aterosclerose
Sociedade Portuguesa de Aterosclerose, Portugal
2008 Honorable Mention for best research project in Urology
Associação Portuguesa de Urologia, Portugal
2006 Best scientific oral presentation - XIV Congresso Português de Aterosclerose
Sociedade Portuguesa de Aterosclerose, Portugal
2004 Best Scientific Research Communication - 6º Congresso Português de Diabetes
Sociedade Portuguesa de Diabetes, Endocrinologia e Metabolismo, Portugal
2004 Best oral presentation - XXIV Congresso da SPOT
Sociedade Portuguesa de Ortopedia e Traumatologia, Portugal
2004 Best research project in Urology - Prémio Jaba Recordati
Associação Portuguesa de Urologia, Portugal
2001 Best Scientific Comunication - Prémio Merk Farma & Química
Sociedade Portuguesa de Aterosclerose, Portugal