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I took my BSc degree in Biochemistry and Food Chemistry at University of Aveiro (UA) in 2008, soon after, I done my MSc in Organic Chemistry and Natural Products at UA (2009), been my master thesis title -Studies of Heck reaction of 3-bromoflavones with styrenes-. In 2010, I was awarded with a research grant that allow me to continue my investigation on synthesis and preparation of new flavonoids derivatives at the Professor Artur Silva group. Later, I was awarded a PhD fellowship in chemistry by FCT (SFRH/BD/68991/2010) where I worked on -Synthesis and transformation of chromones and 4-quinolones-. In September 2016, I started a research fellow for three months, that consisted in synthesis and chemical characterization of pyrazoles, bis-pyrazoles and 1,2-di-hydropyridines. Posteriorly, I worked on DRUGORGINORG project (PT-DZ/0005/2015) where my investigation focus on evaluation of anticancer and anti-tumour effects of organic chemotypes. Between December 2018-Jule 2022, I was junior researcher in the Team of Prof. João Mano on the SUPRASORT and COP2P projects . I worked on chemical functionalization of polymers (natural polysaccharides and proteins) and DNA nucleobases to be used in production biomaterials for biomedical applications. Since February 2023, I am the research member of G-Cork project where I development my investigation on quartz crystal microbalance (QCM) sensors for volatile compounds detection in cork. During my scientific career I had two period of scientific interruption due to maternity (2015 and 2020). I did not develop any laboratory activity, mentoring/ tutoring/ supervision student. Both interruptions had great impact in scientific and pedagogic career (number, planning and quality). I have been synthesized around 170 nitrogen and oxigen derivatives and structurally characterized mainly by Proton and Carbon Nuclear Magnetic Resonance (1H and 13C NMR) and Mass spectroscopy (MS). My PhD thesis was distinguished by the honourable mention in Portuguese Award for best PhD Thesis in Organic Chemistry 2017. The investigation developed during my PhD and years before allowed me to deepen in a further robust way my taste and knowledge in chemical modification and structural characterization of polyphenolics compounds, as well as developing my skills as organic chemist. In 2017, the project DRUGORGINORG allowed me to work in biology science, more precisely in anticancer evaluation of synthetic compounds. I worked at the Institute of Biomedicine (iBiMED) in cell culture and was responsible for the in vitro testing of many compounds (around 70) in 2 breast cancer cell lines (MDA-MB-231) and 1 prostate cancer cell line (PC3). I acquired skills and knowledge in cytotoxicity assays, cycle analysis, flow cytometry and immunohistochemistry. This period was very rich and fascinating for me. As Junior researcher I work in chemical functionalization and structural characterization of laminarin, chitosan, hyaluronic acid, peptides, collagen and DNA nucleobases. Once structurally modified these molecules are used in production biomaterials (hydrogels, membranes) using light (photo-crosslinking), temperature or pH for biomedical applications. Different techniques are used for structural characterization such as RMN, FTIR, UV-Vis, SEM as well as their mechanical and chemical properties using equipment like Instron and Rheometer (viscosity, young's modulus) and swealing behaviour. I do also develop some management work as CO-PI of Suprasort project. In terms of academic work, I am mentoring students and researchers, I supervise 1 BSc and 1 MSc students as co-advisor, I lectured on experimental classes of organic/bioorganic chemistry in Department of Chemistry at UA and was jury of academic degree (Master thesis, seminar and BSc project). Since 2015, I published 14 scientific papers, 1 Portuguese patent (nº 118039), another one submitted, 2 book chapter, 10 oral/poster communications and I am reviewer of journal papers.
Identification

Personal identification

Full name
Djenisa Helene Ascenção Rocha

Citation names

  • Rocha, Djenisa H. A.

Author identifiers

Ciência ID
1B1F-0F26-5BF4
ORCID iD
0000-0002-3508-9135
Researcher Id
7746-2015
Scopus Author Id
55026027700

Email addresses

  • djenisa@ua.pt (Professional)
  • djenisarocha@gmail.com (Personal)

Addresses

  • Universidade de Aveiro - Departamento de Química - Campus Universitário de Santiago, 3810-193, Aveiro, Aveiro, Portugal (Professional)

Knowledge fields

  • Exact Sciences - Chemical Sciences
  • Exact Sciences
  • Engineering and Technology
  • Medical and Health Sciences - Medical Biotechnology - Biomaterials
  • Engineering and Technology - Environmental Engineering - Remote Sensing

Languages

Language Speaking Reading Writing Listening Peer-review
Creole and Pidgin, Portuguese-based (Other) (Mother tongue)
Portuguese Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2015/03/26
Concluded
Doctoral program in Chemistry (Doutoramento)
Universidade de Aveiro, Portugal
""Estudos de síntese e transformação de cromonas e 4-quinolonas" Studies of the synthesis and transformation of chromones and 4-quinolones" (THESIS/DISSERTATION)
Aprovaded
2009
Concluded
Master in Organic Chemistry and Natural Products (Mestrado)
Universidade de Aveiro, Portugal
""Estudos da reação de Heck de 3-bromoflavonas com estirenos" Studies of Heck reaction of 3-bromoflavones with styrenes" (THESIS/DISSERTATION)
15
2008
Concluded
Biochemistry and Food Chemistry (Licenciatura)
Universidade de Aveiro, Portugal
""Síntese de novos compostos com potencial antioxidante" Synthesis of new compounds as potential antioxidant" (THESIS/DISSERTATION)
14
Affiliation

Science

Category
Host institution
Employer
2023/02/20 - 2023/06/30 Contracted Researcher (Research) Universidade de Aveiro CICECO, Portugal
Universidade de Aveiro, Portugal
2018/12/01 - 2022/07/25 Contracted Researcher (Research) Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
Universidade de Aveiro, Portugal
2017/01/01 - 2018/11/30 Researcher (Research) Universidade de Aveiro Departamento de Química, Portugal
2016/09/16 - 2016/12/31 Researcher (Research) Universidade de Aveiro Departamento de Química, Portugal
2011/04/01 - 2015/03/31 Researcher (Research) Universidade de Aveiro Departamento de Química, Portugal
2010/02/02 - 2011/03/31 Researcher (Research) Universidade de Aveiro Departamento de Química, Portugal
Projects

Grant

Designation Funders
2017/01/01 - 2018/11/30 DRUGORGINORG "Organic-Inorganic Chemotypes as Anticancer and Anti-tumor Drugs"
PT-DZ/0005/2015 - DRUGORGINORG
Research Fellow
Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/09/16 - 2016/12/31 Synthesis of pyrazoles, bis-pyrazoles 1,2-di-hydropyridines
UID/QUI/00062/2013
Research Fellow
Universidade de Aveiro Departamento de Química, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/04/01 - 2015/03/31 Synthesis studies and transformation of chromones and 4-quinolones
-
PhD Student Fellow
Universidade de Aveiro Departamento de Química, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/02/02 - 2011/03/31 Studies of synthesis and processing of new type of flavonoids compounds
-
Research Fellow
Universidade de Aveiro Departamento de Química, Portugal
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares
Concluded

Contract

Designation Funders
2023/02/20 - Current Development of monitoring tools for cork volatile compounds (GCork). Co-promotion I&D Amorim
POCl-01-0247-FEDER-070302
Researcher
Universidade de Aveiro CICECO, Portugal
Ongoing
2021/10/01 - 2022/07/25 Efficient methodologies for the conjugation of natural polysaccharides with peptides to obtain multifunctional membranes for periodontal regeneration.
COP2P (projeto nº 030771)
Researcher
Universidade de Aveiro, Portugal

Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/12/01 - 2021/09/30 DNA Base Pairing-based Supramolecular Self-Sorting Devices: A Molecular Recognition and Biomimetic Technology to Screen Target Cells for Biomedical and Healthcare Applications (Suprasort)
PTDC/QUI-OUT/30658/2017
Researcher
Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing

Other

Designation Funders
2021/01/01 - 2022/07/25 DNA Base Pairing-based Supramolecular Self-Sorting Devices: A Molecular Recognition and Biomimetic Technology to Screen Target Cells for Biomedical and Healthcare Applications (Suprasort)
PTDC/QUI-OUT/30658/2017
Co- Principal investigator (Co-PI)
Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Book chapter
  1. Silva, V. L. M.; Pinto, D. C. G. A.; dos Santos, C. M. M.; Rocha, D. H. A.. "15.4.5 Quinolinones and Related Systems (Update 2022)". In Knowledge Updates 2022/3, 182-442. Georg Thieme Verlag KG, 2022.
    Published • 10.1055/sos-sd-115-01218
  2. Rodrigues, J. M. M.; Castanheira, E. J.; Costa, D. C. S.; Rocha, D. H. A.; Borges, J.; Mano, J. F.. "Chapter 8. Extending the Functionality of Marine-origin Polysaccharides Through Chemical Modification for Biomedical Applications". In Soft Matter for Biomedical Applications, 180-204. Royal Society of Chemistry, 2021.
    Published • 10.1039/9781839161124-00180
Conference paper
  1. Rocha, Djenisa H. A.; Leal, Stephanie B.; Seca, Ana M. L.; Pinto, Diana C. G. A.; Silva, Artur M. S.. "New syntheses of potential biologically active xanthones and benzoxanthones". 2013.
Conference poster
  1. Vera Sousa; C.M. Machado; Cristiana F.V. Sousa; Djenisa H. A. Rocha; Vera L.M. Silva; Artur M. S. Silva; João Borges; João F. Mano. "Regioselective functionalization of DNA nucleobases towards a library of nucleobase derivatives for biomedicine". Paper presented in Jornadas CICECO, 2021.
  2. Rocha, Djenisa H. A.; Saher, Liza; Talhi, Oualid; Djemoui, Amar; Naouri, Abdelkader; Quahrani, M. R.; Djemoui, Djamila; et al. "Synthesis and anticancer activity of triazole-benzimidazolechalcone hybrids (PC90)". Paper presented in 13th National Organic Chemistry Meeting 6th National Medicinal Chemistry Meeting, 2020.
  3. Rocha, Djenisa H. A.; Machado, C. M; Silva, Vera L. M.; Silva, Artur M. S.; Borges, João; Mano, João F.. "Extending the functionality of nucleobases through regioselective N-derivatization". Paper presented in XXVI SPQ National Meeting, 2019.
  4. Rocha, Djenisa H.A.; Balsa, Emanuel J. F.; Pinto, Diana C.G.A.. "Synthesis of benzopyran-indole dyads with potential cannabinoid activity (HC31)". Paper presented in 15th National Meeting of Portuguese Society of Chemistry, 2017.
  5. Rocha, Djenisa H. A.; Saidi, Lydia; Talhi, Oualid; Nedjar-Kolli, B.; Bentarzi, Y.; Mendes, Ricardo F.; Paz, Filipe A.A.; et al. "Synthesis of benzophenone derivatives by the reaction of nitromethane with (E)-3-[3-(2-hydroxyphenyl)-3-oxoprop-1-en-1-yl]-4H-chromen-4-ones (HC65)". Paper presented in 15th National Meeting of Portuguese Society of Chemistry, 2017.
  6. Rocha, Djenisa H. A.; Pinto, Diana C.G.A; Silva, Artur M.S.. "Strategies towards the synthesis of new (E)-2-aryl-3-styryl-4H-chromen-4-ones and (E)-1-methyl-2-aryl-3-styrylquinolin-4(1H)-ones (P1.77)". Paper presented in 15th Tetrahedron Symposium – Challenges in Bioorganic and Organic Medicinal Chemistry, 2014.
  7. Rocha, Djenisa H. A.; Pinto, Diana C.G.A.; Silva, Artur M.S.. "Wittig and Heck reaction: two diferent strategies towards the synthesis of (E)-3-styrylflavones (P 1.54)". Paper presented in 13th National Meeting of Portuguese Society of Chemistry, 2013.
  8. Rocha, Djenisa H. A.; Pinto, Diana C.G.A.; Silva, Artur M.S.; Cavaleiro, José A.S.. "3-Styrylflavones synthesis: Heck versus Wittig reactions (P-0279)". Paper presented in 4th EuCheMS Chemistry Congress, 2012.
  9. Rocha, Djenisa H. A.; Pinto, Diana C.G.A.;; Silva, Artur M.S.; Cavaleiro, José A.S.; Patonay, T.. "Synthesis of 3-styrylflavones and their transformation into 2-arylbenzo[c]xanthones (QO-CP 026)". Paper presented in 12th National Meeting of Chemistry, 2011.
  10. Rocha, Djenisa H.A.; Pinto, Diana C.G.A.; Silva, Artur M.S.; Cavaleiro, José A.S.. "Polyhydroxy 3-aroylflavones as potential antioxidant agentes (P47)". Paper presented in North West Organic Chemistry, 2010.
  11. Rocha, Djenisa H. A.; Pinto, Diana C.G.A.; Silva, Artur M.S.; Cavaleiro, José A.S.; Patonay, T.. "New synthesis of 3-styrylflavones (P38)". Paper presented in 2nd Portuguese Young Chemists Meeting – 2PYCheM, 2010.
  12. Rocha, Djenisa H. A.; Pinto, Diana C.G.A.; Silva, Artur M.S.; Cavaleiro, José A.S.; Patonay, T.. "Studies on the Heck reaction of 3-bromoflavones with styrenes (CP59)". Paper presented in 8th National Meeting of Organic Chemistry, 2009.
Journal article
  1. Rocha, Djenisa H. A.; Pinto, Diana C. G. A.; Silva, Artur M. S.. "Macroalgae Specialized Metabolites: Evidence for Their Anti-Inflammatory Health Benefits". Marine Drugs 20 12 (2022): 789. http://dx.doi.org/10.3390/md20120789.
    Published • 10.3390/md20120789
  2. Rocha, Djenisa H. A.; Carmen M. Machado; Vera Sousa; Cristiana F. V. Sousa; Vera L. M. Silva; Artur M. S. Silva; João Borges; João F. Mano. "Customizable and Regioselective One-Pot N-H Functionalization of DNA Nucleobases to Create a Library of Nucleobase Derivatives for Biomedical Applications". European Journal of Organic Chemistry 2021 31 (2021): 4423-4433. https://doi.org/10.1002/ejoc.202100786.
    10.1002/ejoc.202100786
  3. Naouri, Abdelkader; Djemoui, Amar; Ouahrani, Mouhamad Ridha; Lahrech, Mokhtar Boualem; Lemouari, Najet; Rocha, Djenisa H.A.; Albuquerque, Hélio; et al. "Multicomponent and 1,3-dipolar cycloaddition synthesis of triazole- and isoxazole-acridinedione/xanthenedione heterocyclic hybrids: Cytotoxic effects on human cancer cells". Journal of Molecular Structure 1217 (2020): 128325. http://dx.doi.org/10.1016/j.molstruc.2020.128325.
    10.1016/j.molstruc.2020.128325
  4. Rocha, Djenisa H. A.; Batista, Vasco F.; Balsa, Emanuel J. F.; Pinto, Diana C. G. A.; Silva, Artur M. S.. "Chromene- and Quinoline-3-Carbaldehydes: Useful Intermediates in the Synthesis of Heterocyclic Scaffolds". Molecules 25 17 (2020): 3791. http://dx.doi.org/10.3390/molecules25173791.
    10.3390/molecules25173791
  5. Djemoui, Amar; Naouri, Abdelkader; Ouahrani, Mohammed Ridha; Djemoui, Djamila; Lahcene, Souli; Lahrech, Mokhtar Boualem; Boukenna, Leila; et al. "A step-by-step synthesis of triazole-benzimidazole-chalcone hybrids: Anticancer activity in human cells+". Journal of Molecular Structure 1204 (2020): 127487. http://dx.doi.org/10.1016/j.molstruc.2019.127487.
    10.1016/j.molstruc.2019.127487
  6. Rocha, Djenisa H. A.; Vaz, Patrícia A. A. M.; Pinto, Diana C. G. A.; Silva, Artur M. S.. "Synthesis Chalones and Their Isomerization into Flavanones and Azaflavanones". Methods and Protocols 2 3 (2019): 70. http://dx.doi.org/10.3390/mps2030070.
    10.3390/mps2030070
  7. Rocha, Djenisa H. A.; Pinto, Diana C. G. A.; Silva, Artur M. S.. "Synthesis of 4,5-disubstituted-1H-1,2,3-triazoles". Monatshefte für Chemie - Chemical Monthly (2019): http://dx.doi.org/10.1007/s00706-019-02463-x.
    10.1007/s00706-019-02463-x
  8. Saidi, Lydia; Rocha, Djenisa H. A.; Talhi, Oualid; Bentarzi, Yamina; Nedjar-Kolli, Bellara; Bachari, Khaldoun; Almeida Paz, Filipe A.; Helguero, Luisa A.; Silva, Artur M. S.. "Synthesis of Benzophenones and in vitro Evaluation of Their Anticancer Potential in Breast and Prostate Cancer Cells". ChemMedChem 14 10 (2019): 1041-1048. http://dx.doi.org/10.1002/cmdc.201900127.
    10.1002/cmdc.201900127
  9. Rocha, Djenisa H.A.; Pinto, Diana C. G. A.; Seca, Ana M. L.. "Seaweed Secondary Metabolites In Vitro and In Vivo Anticancer Activity". Marine Drugs 16 11 (2018): 410. http://dx.doi.org/10.3390/md16110410.
    10.3390/md16110410
  10. Rocha, Djenisa H. A.; Pinto, Diana C. G. A.; Silva, Artur M. S.. "Applications of the Wittig Reaction on the Synthesis of Natural and Natural-Analogue Heterocyclic Compounds". European Journal of Organic Chemistry 2018 20-21 (2018): 2443-2457. http://dx.doi.org/10.1002/ejoc.201800523.
    10.1002/ejoc.201800523
  11. Silva, Eduarda; Rocha, Djenisa; Silva, Artur. "Diels–Alder Reactions of 1,2-Dihydropyridines: An Efficient Tool for the Synthesis of Isoquinuclidines". Synthesis 50 12 (2018): 2432-2432. http://dx.doi.org/10.1055/s-0036-1589536.
    10.1055/s-0036-1589536
  12. Varandas, Pedro; Rocha, Djenisa H. A.; Silva, Eduarda M. P.; Silva, Artur M.S.; Paz, Filipe. "One-Pot Synthesis of Isoquinuclidines via 2,6-Diaryl-1,2-dihydropyridines using (E,E)-Cinnamylideneacetophenones as Templates". Synthesis 50 10 (2018): 1965-1972. http://dx.doi.org/10.1055/s-0036-1591767.
    10.1055/s-0036-1591767
  13. Silva, E.M.P.; Silva, A.M.S.; Rocha, Djenisa H. A.. "Diels-Alder Reactions of 1,2-Dihydropyridines: An Efficient Tool for the Synthesis of Isoquinuclidines". Synthesis (Germany) 50 9 (2018): 1773-1782. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045152753&partnerID=MN8TOARS.
    10.1055/s-0037-1609418
  14. Talhi, Oualid; Silva, Artur M.S.; Sousa, Joana L. C.; Rocha, Djenisa H.A.; Pinto, Diana C.G.A; Almeida Paz, Filipe; Bachari, Khaldoun; Kirsch, Gilbert. "One-Pot Synthesis of Novel Highly Functionalized Furan-Based Polyphenolics". Synlett 26 19 (2015): 2724-2729. http://dx.doi.org/10.1055/s-0035-1560580.
    10.1055/s-0035-1560580
  15. Rocha, Djenisa H.A.; Pinto, Diana C.G.A.; Silva, Artur M.S.. "Synthesis and cyclisation studies of ( E )-2-aryl-1-methyl-3-styrylquinolin-4(1 H )-ones". Tetrahedron 71 40 (2015): 7717-7721. http://dx.doi.org/10.1016/j.tet.2015.07.058.
    10.1016/j.tet.2015.07.058
  16. Rocha, Djenisa H. A.; Pinto, Diana C. G. A.; Seixas, Raquel S. G. R.; Silva, Artur M. S.. "3-Methylflavones characterization revisited: complete assignment of1H and13C NMR data". Magnetic Resonance in Chemistry 52 1-2 (2013): 47-50. http://dx.doi.org/10.1002/mrc.4026.
    10.1002/mrc.4026
  17. Rocha, Djenisa H.A.; Pinto, Diana C.G.A; Silva, Artur M.S.. "One-Pot Synthesis of 3-Methylflavones and Their Transformation into (E)-3-Styrylflavones via Wittig Reactions". Synlett 24 20 (2013): 2683-2686. http://dx.doi.org/10.1055/s-0033-1340013.
    10.1055/s-0033-1340013
  18. Rocha, Djenisa; Pinto, Diana C.G.A.; Silva, Artur M.S.; Patonay, Tamás; Cavaleiro, José. "A New Synthesis of 5-Arylbenzo[c]xanthones from Photoinduced Electrocyclisation and Oxidation of (E)-3-Styrylflavones". Synlett 23 04 (2012): 559-564. http://dx.doi.org/10.1055/s-0031-1290355.
    10.1055/s-0031-1290355
  19. Rocha, Djenisa H.A.; Pinto, Diana C.G.A; Silva, Artur M. S.; Cavaleiro, Jose A. S.; Vaz, Patrícia A. A. M.. "New Syntheses of 3-Aroylflavone Derivatives; Knoevenagel Condensation and Oxidation versus One-Pot Synthesis". Synlett 16 (2012): 2353-2356. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000309164100009&KeyUID=WOS:000309164100009.
    10.1055/s-0032-1317159
Magazine article
  1. Rocha, Djenisa H.A.; Pinto, Diana C.G.A; Silva, Artur M.S.. "Estudos de síntese e transformação de cromonas e 4-quinolonas", Química- Boletim da SPQ, 2018, https://www.spq.pt/magazines/BSPQuimica/684.
Newsletter article
  1. Rocha, Djenisa H. A.. "Synthesis of Benzophenones and in vitro Evaluation of Their Anticancer Potential in Breast and Prostate Cancer Cells", Associação Portuguesa de Investigação em Cancro (ISPIC), 2019, https://www.aspic.pt/pt-pt/node/6827#.YBQhFOj7RPZ.
Thesis / Dissertation
  1. Silva, Artur Manuel Soares da; Pinto, Diana Claúdia Gouveia Alves; Rocha, Djenisa Helene Ascenção. "Estudos de síntese e transformação de cromonas e 4-quinolonas". PhD, 2015. http://hdl.handle.net/10773/14472.
  2. Pinto, Diana Cláudia Gouveia Alves; Silva, Artur Manuel Soares da; Rocha, Djenisa Helene Ascenção. "Estudos da reacção de Heck de 3-bromoflavonas com estirenos". Master, 2009. http://hdl.handle.net/10773/4551.

Intellectual property

Patent
  1. João F. Mano; João Borges; Vera Sousa; Djenisa H. A. Rocha. 2023. "HIDROGÉIS SUPRAMOLECULARES DE G-QUADRUPLEXOS, PROCESSOS DE PRODUÇÃO E USO DOS MESMOS". Portugal.
    Granted/Issued
  2. João F. Mano; João M. M. Rodrigues; Luís P. G. Monteiro; Djenisa H. A. Rocha. 2023. "POLISSACARÍDEOS NATURAIS CARREGADOS POSITIVA OU NEGATIVAMENTE, METODOLOGIA PARA A OBTENÇÃO DOS MESMOS E APLICAÇÕES". Portugal.
    Pending
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/08 Customizable and regioselective NH functionalization of nucleobases towards advanced biopolymer conjugates for biomedicine IUPAC Word Chemistry Congress Virtual
2021/05 Regioselective NH functionalization of DNA nucleobases towards advanced biopolymer conjugates for biomedical applications 7 th Portuguese Young Chemists Meeting
(Bragança)
2018/01/17 The footprint of organic chemistry in the synthesis of xanthone and acridone scaffolds (OC8, pg. 78) 12th National Meeting of Organic Chemistry and 5th Therapeutic Chemistry Meeting
(Coimbra, Portugal)
2015/12/01 Strategies towards the synthesis of new (E)-2-aryl-3-styryl-4H-chromen-4-ones and (E)-1-methyl-2-aryl-3-styrylquinolin-4(1H)-ones (OC-9, pg. 45) 11th National Meeting of Organic Chemistry and 4th Therapeutic Chemistry Meeting
(Porto, Portugal)
2013/09/04 New syntheses of potential biologically active xanthones and benzoxanthones ( IOC4, pg. 61) 10th National Meeting of Organic Chemistry and 1st Luso-Brasileiro Symposium of Organic Chemistry
(Lisboa, Portugal)
2013/09/04 Biological activities of oxygen and nitrogen heterocyclic compounds (IOC3, pg. 60) 0th National Meeting of Organic Chemistry and 1st Luso-Brasileiro Symposium of Organic Chemistry
(Lisboa, Portugal)
2012/08/13 New syntheses of novel arylxanthones (PO-39) 15th European Colloquium on Heterocyclic Chemistry
(Reading, United Kingdom)
2011/11/09 An easy synthetic approach to 1,2,3-triazole heterocycles (F-20, pg. 48) XVII Luso-Galego Meeting of Chemistry
(Pontevedra, Spain)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2021/10/01 - 2022/12/15 "Intelligent hydrogels for cartilage regeneration" The work developed in the master's thesis aimed the preparetion of CHI hydrogel that promotes cartilage regeneration, by attenuating inflammation, from the phased release of D-glucosamine units by the action of encapsulated enzymes.
Co-supervisor
Masters degree in Molecular Biotechnology and Bioengineering (Master)
Universidade de Aveiro, Portugal
2021/03/15 - 2021/09/10 "Development of conjugates N-glucosamine/flavone with potential biological applications" This project propose the synthesis of hybrids combining N-glucosamine with flavones using simple coupling methodologies: Heck reaction. The structure of flavones and N-glucosamine was functionalyzed with specific terminal (alkene, and halogen) for doing the coupling reaction between these scaffolds.
Co-supervisor
Biochemistry (Degree)
Universidade de Aveiro, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2019/10/21 - 2019/10/23 3rd Training school under COST action EBNA entitled Bioinspired Adhesive Hydrogels and Polymers. Some practical experiments were shown to foreign students (2019/10/21 - 2019/10/23)
Workshop (Co-organisor)
Universidade de Aveiro CICECO, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2021/09/21 Indolylmethyl Pyrazinoquinazoline Alkaloids inspired by the sea: Total synthesis and evaluation of antimicrobial activities
(Thesis) Main arguer
Mariana da Costa Almeida (Master)
Universidade do Porto Faculdade de Farmácia, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2020/07/16 - 2023/05/12 Applied Science (2673-3161) MDPI
2020/09/21 - 2023/02/17 Molecules (1420-3049) MDPI
2022/02/12 - 2022/02/12 New Journal of Chemistry (1144-0546) Royal Society of Chemistry
2021/12/02 - 2022/02/12 Pharmaceuticals (1424-8247) MDPI
2022/01/07 - 2022/01/14 Journal of Aquatic Food Product Technology Taylor and Francis Online
2021/01/05 - 2021/09/27 International Journal of Molecular Science (IJMS) (1422-0067) MDPI
2021/09/06 - 2021/09/06 Materials (1996-1944) MDPI
2021/07/20 - 2021/07/20 Membranes (2077-0375) MDPI
2020/10/27 - 2020/11/03 Journal Molecular Structure (00222860) Elsevier
2020/10/21 - 2020/10/30 Nutrients (2072-6643) MDPI
2020/03/06 - 2020/08/16 Marine Drugs (1660-3397) MDPI

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021/03/23 - 2021/06/30 Laboratory of Biorganic Chemistry (QB). Practical classes. During these classes the students done 5 works, 3 laboratory techniques (distillations, chromatography separation, extraction and purification) and 2 chemical properties of aminoacids and carbohydrates. They has 2 discussion classes where the works were discussed and doubts were cleared. The continuous evaluation of these students was under my responsibility as well as the monitoring of classes. Laboratory of Biorganic chemistry (Licenciatura) Universidade de Aveiro, Portugal
2020/03/20 - 2020/06/07 Laboratory of Biorganic Chemistry (QB). Practical classes. The continuous evaluation of these students was under my responsibility as well as the monitoring/supervision and teaching of classes. Laboratory of biorganic Chemistry (Licenciatura) Universidade de Aveiro, Portugal
2019/09/23 - 2019/12/09 Laboratory of Organic Chemistry-Physical Chemistry (QO-QF). Practical classes. During these classes the students done 8 works, 5 laboratory techniques (distillations, dialysis, chromatography separation, extraction and purification) and 3 synthesis (chalcone, hypuric acid and benzaldazine). The students done 2 complete reports and 6 summary reports. They also had 2 discussion classes where the works were discussed and doubts were cleared. The continuous evaluation of these students was under my responsibility as well as the monitoring of classes. Laboratory QO-QF (Mestrado integrado) Universidade de Aveiro, Portugal

Mentoring / Tutoring

Topic Student name
2020/03/18 - Current DNA nucleobase and polymers chemical functionalization Vera Sousa
2019/04/01 - 2019/12 DNA nucleobase chemical functionalization Mariana Machado
2019/01/02 - 2019/06/30 Synthesis and characterization of polyphenolic compounds (acetophenone and coumarin) Lakhdari Houria
2019/01/02 - 2019/06/30 Synthesis and characterization of polyphenolic compounds (acetophenone and coumarin) Brahim Cherfaoui
2018/09/30 - 2018/10/31 Cytotoxicity assays Ana Sofia Santos Dias
2018/02/05 - 2018/10 Synthesis and characterization of polyphenolic compounds Liza Saher

Other jury / evaluation

Activity description Institution / Organization
2022/09/02 - 2022/09/02 Evaluation of monograph for the Chair of Seminars in Biotechnology. Course : Master’s degree in Industrial and Environmental Biotechnology Tithe of monograph: 3D Printing Human-Based Nanocomposite Biomaterial Inks for Tissue Regeneration Candidate: João M. Maia Universidade de Aveiro, Portugal
Distinctions

Other distinction

2018 Honorable Mention in Portuguese Award for best PhD Thesis in Organic Chemistry 2017