???global.info.a_carregar???
Isabel Maria Nunes Correia obtained her Ph.D. in Biochemistry in 2007 from the University of Coimbra, Faculty of Sciences and Technology. Additionally, she holds a Master's degree in Cellular Biology, earned in 1999, and a Bachelor's degree in Biochemistry from 1994, both achieved at the University of Coimbra, Faculty of Sciences and Technology. Currently, she is a Senior Technician at the Center for Neuroscience and Cell Biology, where she coordinates crucial and comprehensive structures essential for research activities. This encompasses the coordination of the Flow Cytometry Unit and the management of laboratories dedicated to cell culture. In her managerial capacity, Isabel gives support and training to new users within the structures she oversees, ensuring the adoption of good laboratory practices. Since 2021, she additionally assumed the position of Executive Administrator for the Doctoral Program in Experimental Biology and Biomedicine. Over the years, she engaged in teaching at the higher education level, focusing on Cellular Biology and Biochemistry. Isabel's scholarly contributions include the publication of 15 articles in specialized journals. Her Ciência Vitae curriculum underscores key terms such as African swine fever virus, nuclear-cytoplasmic transport, influenza virus, lipid-enveloped virus, membrane fusion, fluorescent probes, and flow cytometry within the context of her scientific and technological production.
Read full resume ↓
Identification

Personal identification

Full name
Isabel Maria Nunes Correia

Citation names

  • Nunes-Correia, Isabel
  • Nunes, Isabel

Author identifiers

Ciência ID
1A1F-C9F8-E978
ORCID iD
0000-0001-7470-0542

Email addresses

  • inunes@cnc.uc.pt (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Cell Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Spanish; Castilian Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2007
Concluded
 Biochemistry (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Interacção de vírus providos de envelope lipídico com células em cultura: das fases iniciais de internalização à importação nuclear" (THESIS/DISSERTATION)
 Very Good
1999
Concluded
 Masters in Cell Biology (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Análise cinética dos primeiros passos envolvidos na infecção celular promovida pelo vírus influenza" (THESIS/DISSERTATION)
 Very Good
1994
Concluded
 Biochemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Estudo da fusão do vírus Sendai com membranas plasmáticas de eritrócitos" (THESIS/DISSERTATION)
 Good - 14
Affiliation

Others

Category
Host institution 		Employer
2006/04/01 - Current Laboratory Technician, responsible for the Flow Cytometry Unit, for the cell culture rooms and for some other equipment. Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009/01/01 - 2011/01/31 Assistant Professor (partial time) Escola Universitária Vasco da Gama, Portugal
2000/01/01 - 2007 Ph.D student Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2004/05/04 - 2004/12/20 Visiting Scientist Universidad Autonoma de Madrid Centro de Biología Molecular Severo Ochoa, Spain
Universidad Autonoma de Madrid Centro de Biología Molecular Severo Ochoa, Spain
2000/04/03 - 2000/05/19 Visiting Scientist Stony Brook University, United States
2000/04/03 - 2000/05/19 Visiting Scientist Universidade de Coimbra, Portugal
1995/01/01 - 1999 Master student Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Projects

Contract

Designation Funders
2010/02/05 - 2013/05/31 Alteração do tráfego intracelular mediado pela mitocôndria na doença de Parkinson
PTDC/SAU-NEU/102710/2008
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/05/01 - 2010/12/31 Desenvolvimento de novas estratégias para terapia anti-tumoral baseadas na utilização do peptídeo permeante S413-PV com o objectivo de potenciar a entrega intracelular de ácidos nucleicos e proteínas com actividade terapêutica
PTDC/BIO/65627/2006
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2003 - 2006 Mechanisms of nucleo-cytoplasmic trafficking of ASFV genome and designof anti-NLS/NES backbone cyclic peptides to prevent viral infection.
POCTI/CVT/44854/2002
Other
Fundação para a Ciência e a Tecnologia
Concluded
2002 - 2005 Mechanisms of nucleo-cytoplasmic trafficking of ASFV genome and design of anti-NLS/NES backbone cyclic peptides to prevent viral infection
POCTI/CVT/42700/2001
Other
Fundação para a Ciência e a Tecnologia
Concluded
2000/09/01 - 2004/08/31 ESTUDO DOS MECANISMOS MOLECULARES ENVOLVIDOS NA TRANSLOCAÇÃO DO DNA DO VÍRUS DA PESTE SUÍNA AFRICANA PARA O NÚCLEO DE CÉLULAS INFECTADAS
PRAXIS XXI/BD/21347/99
Universidade de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
1997 - 2000 Non-viral gene transfer vectors
EC BIO4-CT97-2191
Other
Concluded
Outputs

Publications

Journal article
  1. Gaspar, Ricardo; de Matos, Mafalda Ramos; Cortes, Luísa; Nunes-Correia, Isabel; Todo-Bom, Ana; Pires, Euclides; Veríssimo, Paula. "Pollen Proteases Play Multiple Roles in Allergic Disorders". International Journal of Molecular Sciences 21 10 (2020): 3578. http://dx.doi.org/10.3390/ijms21103578.
    Published • 10.3390/ijms21103578
  2. Oliveira Miranda, Catarina; Marcelo, Adriana; Silva, Teresa Pereira; Barata, João; Vasconcelos-Ferreira, Ana; Pereira, Dina; Nóbrega, Clévio; et al. "Repeated Mesenchymal Stromal Cell Treatment Sustainably Alleviates Machado-Joseph Disease". Molecular Therapy 26 9 (2018): 2131-2151. http://dx.doi.org/10.1016/j.ymthe.2018.07.007.
    Published • 10.1016/j.ymthe.2018.07.007
  3. Ferreira, S.G.; Gonçalves, F.Q.; Marques, J.M.; Tomé, A.R.; Rodrigues, R.J.; Nunes-Correia, I.; Ledent, C.; et al. "Presynaptic adenosine A2A receptors dampen cannabinoid CB1 receptor-mediated inhibition of corticostriatal glutamatergic transmission". British Journal of Pharmacology (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84921269252&partnerID=MN8TOARS.
    10.1111/bph.12970
  4. Ribeiro MP; Nunes-Correia I; Santos AE; Custódio JB; Ribeiro, Mariana P. C.; Nunes-Correia, Isabel; Santos, Armanda E.; Custódio, José B. A.. "The combination of glutamate receptor antagonist MK-801 with tamoxifen and its active metabolites potentiates their antiproliferative activity in mouse melanoma K1735-M2 cells.". (2014): http://europepmc.org/abstract/med/24240127.
    10.1016/j.yexcr.2013.11.002
  5. Morte, M.I.; Carreira, B.P.; Machado, V.; Carmo, A.; Nunes-Correia, I.; Carvalho, C.M.; Araújo, I.M.; et al. "Evaluation of proliferation of neural stem cells in vitro and in vivo". Current Protocols in Stem Cell Biology 1 SUPPL.24 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84880828319&partnerID=MN8TOARS.
    10.1002/9780470151808.sc02d14s24
  6. Carmo, A.; Carvalheiro, H.; Crespo, I.; Nunes, I.; Lopes, M.C.. "Effect of temozolomide on the U-118 glioma cell line". Oncology Letters 2 6 (2011): 1165-1170. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052752206&partnerID=MN8TOARS.
    10.3892/ol.2011.406
  7. Nunes-Correia, Isabel; Rodríguez, Javier M.; Eulálio, Ana; Carvalho, Ana L.; Citovsky, Vitaly; Simões, Sérgio; Faro, Carlos; et al. "African swine fever virus p10 protein exhibits nuclear import capacity and accumulates in the nucleus during viral infection". Veterinary Microbiology 130 1-2 (2008): 47-59. http://hdl.handle.net/10316/3853.
    10.1016/j.vetmic.2007.12.010
  8. Eulálio, Ana; Nunes-Correia, Isabel; Salas, José; Salas, Maria L.; Simões, Sergio; Pedroso de Lima, Maria C.; Eulálio, A.; et al. "African swine fever virus p37 structural protein is localized in nuclear foci containing the viral DNA at early post-infection times". The replication of African swine fever virus DNA is initiated inside the nucleus of host cells, being followed by a longer cytoplasmic replication stage. In face of previous results demonstrating the nucleo-cytoplasmic shuttling activity of ASFV p37 structural protein when considered isolated from the virus infection, we performed a systematic analysis of the subcellular localization of p37 protei 130 1-2 (2007): 18-27. http://hdl.handle.net/10316/3856.
    10.1016/j.virusres.2007.05.009
  9. Eulálio, A.; Nunes-Correia, I.; Carvalho, A.L.; Faro, C.; Citovsky, V.; Salas, J.; Salas, M.L.; et al. "Nuclear export of African swine fever virus p37 protein occurs through two distinct pathways and is mediated by three independent signals". Journal of Virology 80 3 (2006): 1393-1404. http://www.scopus.com/inward/record.url?eid=2-s2.0-31144441675&partnerID=MN8TOARS.
    10.1128/JVI.80.3.1393-1404.2006
  10. Eulálio, A.; Nunes-Correia, I.; Carvalho, A.L.; Faro, C.; Citovsky, V.; Simões, S.; De Lima, M.C.P.. "Two African swine fever virus proteins derived from a common precursor exhibit different nucleocytoplasmic transport activities". Journal of Virology 78 18 (2004): 9731-9739. http://www.scopus.com/inward/record.url?eid=2-s2.0-4444281591&partnerID=MN8TOARS.
    10.1128/JVI.78.18.9731-9739.2004
  11. Nunes-Correia, I.; Eulálio, A.; Nir, S.; Pedroso De Lima, M.C.; Nunes-Correia, Isabel; Eulálio, Ana; Nir, Shlomo; Lima, Maria C. Pedroso de. "Caveolae as an additional route for influenza virus endocytosis in MDCK cells". Cellular and Molecular Biology Letters 9 1 (2004): 47-60. http://www.scopus.com/inward/record.url?eid=2-s2.0-2342439156&partnerID=MN8TOARS.
  12. Nunes-Correia, I.; Nir, S.; Pedroso De Lima, M.C.. "Kinetics of influenza virus fusion with the endosomal and plasma membranes of cultured cells. Effect of temperature". Journal of Membrane Biology 195 1 (2003): 21-26. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141540481&partnerID=MN8TOARS.
    10.1007/s00232-003-2040-x
  13. Nunes-Correia, Isabel; Eulálio, Ana; Nir, Shlomo; Düzgünes, Nejat; Ramalho-Santos, João; Pedroso de Lima, Maria C. "Fluorescent probes for monitoring virus fusion kinetics: comparative evaluation of reliability". Biochimica et Biophysica Acta (BBA) - Biomembranes 1561 1 (2002): 65-75. http://dx.doi.org/10.1016/s0005-2736(01)00457-6.
    10.1016/s0005-2736(01)00457-6
  14. Nunes-Correia, I.; Ramalho-Santos, J.; Nir, S.; Pedroso De Lima, M.C.. "Interactions of influenza virus with cultured cells: Detailed kinetic modeling of binding and endocytosis". Biochemistry 38 3 (1999): 1095-1101. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033579938&partnerID=MN8TOARS.
    10.1021/bi9812524
  15. Nunes-Correia, I.; Ramalho-Santos, J.; Pedroso De Lima, M.C.. "Sendai virus fusion activity as modulated by target membrane components". Bioscience Reports 18 2 (1998): 59-68. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031727161&partnerID=MN8TOARS.
    10.1023/A:1020180109275
Thesis / Dissertation
  1. Correia, Isabel Maria Nunes. "Interacção de vírus providos de envelope lipídico com células em cultura : das fases iniciais de internalização à importação nuclear". PhD, 2007. http://hdl.handle.net/10316/2085.
Activities

Other jury / evaluation

Activity description Institution / Organization
2024/02/15 - 2024/02/15 Postdoctoral Research Grants Universidade de Coimbra, Portugal
2022/03/20 - 2022/06/07 Selection of Doctoral Candidates to for the PDBEB Programme, 20th Edition Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal