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Elsa Anes is Full Professor in Microbiology and Immunology at the Faculty of Pharmacy University of Lisbon (FFUL). She obtained the degree in Pharmaceutical Sciences in 1988 and started her teaching career as Assistante Professor at FFUL. The PhD work focused on the construction of bacteriophage Ms6 based integrative vectors for the development of recombinant vaccines in BCG, under the supervision of Prof. Moniz Pereira. After the PhD in Pharmacy-Microbiology in 1998, she moves the research area to the Cell Biology of Mycobacteria Infection. In 2000, she did a post graduation in Molecular Biology of the Cell (Alice Dautry, Daniel Louvard, Pascale Cossart) at the Institute Pasteur, Paris a starting point for a postdoctoral formation at EMBL in Heidelberg (Gareth Griffiths laboratory), with the support of EMBO and Gulbenkian fellowships (2000-2005). Her work focused on the role of cytoskeleton during mycobacteria phagocytosis to decipher pathways of tuberculosis bacilli pathogenesis. ______________________________________________________________________________________________________________________________ In parallel she started her independent research group at Retrovirus and Associated Infections unit- Molecular Center for Pathogenesis, faculty of Pharmacy-ULisboa (URIA-CPM-FFUL) as head of the Host-Mycobateria Interactions group. In 2007, she was accepted as external group leader at the Institute of Molecular Medicine, FMUL after positive evaluation by an international group of experts (Ulrich Schaible, H.C.Krausslich, Anne O'Garra, Philippe Sansonetti, Alain Fischer). Since 2014 she is the head of Host-Pathogen Interactions (HPI) laboratory, Research Institute for Medicines (iMed-FFUL). As a pharmacist trained in microbiology, immunology and cell biology, she focus the research on host cell factors that contribute to TB control as well as the M. tuberculosis factors that this pathogen uses to highjack host cells: how it manipulates gene expression, the cytoskeleton, vesicle trafficking, and innate/adaptive immune responses including inflammasome activation and the activity of antimicrobial proteases. In addition she has been enrolled in the development of new antimycobacterials targeting TB bacilli. Her lab is providing the basis for the development of novel therapeutic and diagnostic for TB including during co-infection with HIV. ___________________________________________________________________________________________________________________________ Simultaneously to the research activities as Professor at FFUL she coordinated Cellular Biology, and presently Immunology (both from MICF course near 250 students per year), Cellular Microbiology and Applied Microbiology (2nd cycle masters, near 30 students per year). She has published more than 50 articles/book chapters in international journals, gathering more than 2100 citations (H-index=25 scopus); successfully supervised several MSc, PhD and Post-doctoral fellows; has been PI in several competitive funded grants. She participated as teacher in International PhD programmes as the EMBL pre-doc course (2000-2005); The EMBO/University of Cape Town PhD and post-doc course On Functional Microscopy of Host Pathogen Interactions (Elsa Anes, Phillipe Bastien, Gareth Griffiths, Jacomine Krijnse Locker, Rainer Pepperkok, David Russel, Ulrich Schaible, Michael Way, Peer Bork, Timo Zimmermann), South Africa 2005. Elsa Anes has been invited to participate in the evaluation process of grants and projects by several national (e.g., FCT) and international (e.g., European Commission) programs like HADEA Horizon HLTH-2022 Europe, Agence Nacional de Researche (ANR) France, South Africa National Research Foundation, Medical Research Council, UK, Biotechnology and Biological Sciences Research Council UKRI (UK research and innovation) and, Welcome Trust. She is Associate editor at Frontiers in Immunology /Frontiers in Tuberculosis and review editor in several scientific journals.
Identification

Personal identification

Full name
ELSA MARIA RIBEIRO DOS SANTOS ANES

Citation names

  • ANES, ELSA

Author identifiers

Ciência ID
1A10-7DAD-D860
ORCID iD
0000-0001-5934-0198
Researcher Id
K-3124-2013
Scopus Author Id
6507064447

Addresses

  • Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Lisboa, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Immunology
  • Medical and Health Sciences - Health Sciences - Infectious Diseases

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Proficiency (C2) Advanced (C1) Proficiency (C2)
French Advanced (C1) Advanced (C1) Intermediate (B1) Advanced (C1)
Spanish; Castilian Intermediate (B1) Advanced (C1) Beginner (A1) Intermediate (B1)
Portuguese (Mother tongue)
Education
Degree Classification
2013/02/27 - 2013/02/28
Concluded
Agregação em Microbiologia e Imunologia. (Título de Agregado)
Major in Microbiologia e Imunologia
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Lição de Síntese “For host factors weddings and a Koch’s bacillus funeral: actin, lipids, phagosome maturation and inflammasome activation" (THESIS/DISSERTATION)
Aprovado por unanimidade
1994 - 1998
Concluded
Doutoramento em Farmácia- Microbiologia (Doutoramento)
Major in Microbiologia
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Recombinação em alvo especício em Mycobactérias: o sistema integrativo do micobacteriófago Ms6" (THESIS/DISSERTATION)
Summa cum Laude
1989/09/02 - 1992/12/02
Concluded
Provas de Aptidão Pedagógica e Científica (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Integração e expressão de DNA heterólogo em M. smegmatis, por lisogenia, utilizando um derivado do bacteriófago Ms6. Transformação bacteriana: Introdução de DNA plasmídico na E.coli por electroporação." (THESIS/DISSERTATION)
Aprovado com Distinção e Louvor
1982 - 1988
Concluded
Ciências Farmacêuticas (Licenciatura)
Major in Análises Químico Biológicas
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Análises Químico Biológicas" (THESIS/DISSERTATION)
17 ( 17/20)
Affiliation

Teaching in Higher Education

Category
Host institution
Employer
2023/07/15 - Current Full Professor (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2009/09/09 - 2023/07/15 Associate Professor (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
1998/11/01 - 2009/02/28 Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal
1992/11/01 - 1998/11/30 Assistant (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal
1988/11/01 - 1992/12/30 Trainee Assistant (University Teacher) Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal

Positions / Appointments

Category
Host institution
Employer
2023/02 - Current Associate editor Frontiers Media SA, Switzerland
Frontiers in Tuberculosis, Switzerland
2021/11/25 - Current Membro do Conselho Científico Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/01/02 - Current Associate Editor Microbial Immunology Frontiers Media SA, Switzerland
Frontiers in Immunology, Switzerland
2020/01/02 - Current Associate Editor Microbial Immunology Frontiers Media SA, Switzerland
Frontiers in Microbiology, Switzerland
2019/02/01 - Current Review Editor for Microbes and Innate Immunity Frontiers Media SA, Switzerland
Frontiers in Cellular and Infection Microbiology, Switzerland
2018/09/01 - Current Membro do Conselho Pedagógico Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/02/01 - Current Review Editor for Inflammation Frontiers Media SA, Switzerland
Frontiers in Immunology, Switzerland
2001/09/01 - 2006/07/31 Membro do Conselho Científico Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2001/09/01 - 2006/07/31 Presidente Sub-grupo Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal

Others

Category
Host institution
Employer
2014/01/01 - Current Líder de grupo das Interacções Hospedeiro-Patogeno/ Head of Host-Pathogen interactions Unit Universidade de Lisboa Faculdade de Farmácia, Portugal
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2000/03/01 - 2015/12/31 Líder de grupo CPM-URIA/ Membre of CPM-URIA/ Head of Mycobacteria-host Interactions Unit Universidade de Lisboa Faculdade de Farmácia, Portugal
URIA- Centro de Patogénese Molecular Faculdade de farmácia Universidade Lisboa, Portugal
2008/01/01 - 2015/01/02 Líder de grupo Elsa Anes Lab.(Unidade externa IMM) Group leader of Elsa Anes Lab. (External Unit) Universidade de Lisboa Faculdade de Farmácia, Portugal
Instituto de Medicina Molecular, Portugal
2000/09/02 - 2005/11/30 Investigador visitante/ Postdoc visitor European Molecular Biology Laboratory, Germany
1992/03/01 - 1998/02/01 Investigador no CPM-URIA/ Membre of CPM-URIA/ Universidade de Lisboa Faculdade de Farmácia, Portugal
URIA- Centro de Patogénese Molecular Faculdade de farmácia Universidade Lisboa, Portugal
Projects

Grant

Designation Funders
2005/01/01 - 2006/01/01 Functional microscopy of host-pathogen interactions. EMBO Award ASTF 185b-05
EMBO Award ASTF 185b-05
Post-doc Fellow
European Molecular Biology Laboratory, Germany
Concluded
2001/09/01 - 2001/12/01 Interaction of mycobacteria with actin cytoskeleton. Bolsa Gulbenkian
Gulbenkian
Invited Scientist Fellow
Concluded
2000/09/01 - 2001/01/01 Cytoskeleton phagosome interactions at early and later stages of Mycobacterium spp macrophage phagocytosis. EMBO Award ASTF9678
EMBO ASTF9678
Post-doc Fellow
European Molecular Biology Laboratory, Germany
Concluded

Contract

Designation Funders
2022/04 - 2024/03/31 Development and validation of a 3D cell culture model of the tuberculosis granuloma that can be applied for drug discovery and host cellular studies in the context of a latent infection and multicellular immunologic response
FCT: EXPL/SAU-INF/0742/2021
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022 - 2024/03/31 Potential of nitrobenzoic acid derivatives as antituberculosis drugs. Insights into the mechanism of action.
EXPL/SAU-INF/1097/2021
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/10 - 2022/09 A new approach to fight tuberculosis: co-drugs activated by mycobacterial esterases.
PTDC/SAU-INF/28080/2017
Co-Investigador responsável
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/10 - 2022/09 Phage-Enzybiotic: dealing with critical pathogenic antibiotic-resistant bacteria
PTDC/BTM-SAL/28978/2017
Co-Investigador Responsável
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/10 - 2022/09 Clinical significance of Mycobacterium tuberculosis cell wall structural diversity: contribution to novel mechanisms of antibiotic resistance and relevance towards tuberculosis progression and treatment.
PTDC/BIA-MIC/31233/2017
Co-Investigador Responsável
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/08 - 2022/07 Manipulation of lysosomal cathepsins and their inhibitors cystatins in human macrophages as a host directed therapeutic strategy for tuberculosis and co-infection with HIV.
PTDC/SAU-INF/28182/2017
Principal investigator
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2020/01/01 - 2021/03/26 Dementia associated with HIV infection – study of infectious and inflammatory mechanisms mediated by extracellular vesicles
Gillead 2019
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Gillead
Concluded
2020/06 - 2020/12 SafeS4Life - Long-term active surface protection to SARS-CoV-2 contamination
613670125
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
Concluded
2017/01/01 - 2019/12/30 Role of ectosomes in the dissemination of HIV infection of the CNS and its contribute for the pathogenesis of HIV-associated dementia
Gillead2017
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Gillead
Concluded
2017 - 2018 Mycobacterium tuberculosis modulates miR-106b-5p to control Cathepsin S expression resulting in higher pathogen survival and poor T cell activation.
Janssen2017
Principal investigator
Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Janssen Pharmaceuticals Inc
Concluded
2016 - 2017 Role of Cathepsins in Mycobacterium tuberculosis Survival in Human Macrophages.
Jansen2016
Principal investigator
Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Janssen Pharmaceuticals Inc
Concluded
2010/04 - 2013/12 A new life for old antimycobacterial drugs: development of prodrugs of pyrazinoic acid activated by mycobacterial esterases as a way to circumvent resistance to pyrazinamide
Researcher
URIA- Centro de Patogénese Molecular Faculdade de farmácia Universidade Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/03 - 2013/08 Enhancing the killing of intracellular multi-drug resistant tuberculosis (MDRTB) by human macrophages: a new chemotherapeutic strategy to fight MDRTB.
Researcher
URIA- Centro de Patogénese Molecular Faculdade de farmácia Universidade Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/02 - 2013/07 Role of M. tuberculosis in microRNA controlling of actin assembly and other pro-inflammatory signals in infected macrophages.
Principal investigator
URIA- Centro de Patogénese Molecular Faculdade de farmácia Universidade Lisboa, Portugal

Instituto de Medicina Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/02 - 2013/07 Dissecting the intracelllular traffficking factors involved in M. tuberculosis killing/survival within human macrophages using RNA interference.
Principal investigator
URIA- Centro de Patogénese Molecular Faculdade de farmácia Universidade Lisboa, Portugal

Instituto de Medicina Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2009/01 - 2012/06 Interference of Mycobacterium tuberculosis with the endocytic/antigen presentation pathways on macrophages and dendritic cells from healthy and immunocompromised donnors
Principal investigator
URIA- Centro de Patogénese Molecular Faculdade de farmácia Universidade Lisboa, Portugal

Instituto de Medicina Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/01 - 2009/06 Identification and manipulation of phagosomal signaling networks to activate killing mechanisms of macrophages infected with mycobacteria
Principal investigator
URIA- Centro de Patogénese Molecular Faculdade de farmácia Universidade Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2008 - 2009 INTERACTIONS BETWEEN TUBERCULOSIS CAUSING BACTERIA AND DENDRITIC CELLS
Bilateral SLO-PT
Principal investigator
Universidade de Lisboa Faculdade de Farmácia, Portugal

URIA- Centro de Patogénese Molecular Faculdade de farmácia Universidade Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2005/07 - 2006/12 Identification and manipulation of phagosomal signaling networks to activate killing mechanisms of macrophages infected with mycobacteria
Principal investigator
URIA- Centro de Patogénese Molecular Faculdade de farmácia Universidade Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2002/02 - 2005/08 Interaction between actin cytoskeleton-phagosomes during macrophage infection by mycobacteria.
Provided by PTCRIS: 38983
Principal investigator
URIA- Centro de Patogénese Molecular Faculdade de farmácia Universidade Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
1993/02 - 1996/01 Construction of stable recombinant BCG and other live mycobacterial vaccines
Researcher
URIA- Centro de Patogénese Molecular Faculdade de farmácia Universidade Lisboa, Portugal
European Commission
Concluded
1988/03/01 - 1988/11/01 Desenvolvimento de um sistema de Clonagem e Expressão Genética em Micobactérias
subsidiado pela J.N.I.C.T. (Projecto de Investigação 87/403)
Scientific Initiation Fellow
Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. ANES, ELSA; José Miguel Azevedo-Pereira. "Resposta Imunológica à Infeção Gripal". In Manual Sobre a Gripe (1ª Edição); H Rebelo Andrade, F. Froes (Eds.)., 47-71. Portugal: Lidel; Portugal, 2018.
    Published
  2. ANES, ELSA. Corresponding author: ANES, ELSA. "Acting on Actin During Bacterial Infection". In Cytoskeleton - Structure, Dynamics, Function and Disease. InTech, 2017.
    Published • 10.5772/66861
  3. ANES, ELSA. "Mycobacterial infection of macrophages: the effect of the multiplicity of infection". In Antimicrobial Research: Novel bioknowledge and educational programs, edited by Mendez-Vilas, 651-664. Spain: Formatex Research Center ISBN-13:978-84-947512-0-2, 2017.
    Published
  4. ANES, ELSA. Corresponding author: ANES, ELSA. "For Host Factors Weddings and a Koch’s Bacillus Funeral: Actin, Lipids, Phagosome Maturation and Inflammasome Activation". In Understanding Tuberculosis - Analyzing the Origin of Mycobacterium Tuberculosis Pathogenicity. InTech, 2012.
    10.5772/29592
  5. ANES, ELSA. "Application of confocal microscopy for quantification of intracellular mycobacteria in macrophages.". In Microscopy: Science, Technology, Applications and Education, edited by Mendez-Vilas; J.Dias, 614-621. Spain: Formatex ISBN-13:978-84-614-6189-9, 2010.
    Published
  6. ANES, ELSA; Simões, Marta Filipa. Corresponding author: ANES, ELSA. "Efeito de anti-inflamatórios não esteróides no Mycobacterium tuberculosis. 8th virtual congress HIV-AIDS. http: //www.aidscongress.net/pdf/341.pdf, ISBN: 978-972-95977-7-0". In 8th virtual congress HIV-AIDS.. Portugal, 2008.
    Published
  7. ANES, ELSA; Luisa Jordão; Luis Constantino. Corresponding author: ANES, ELSA. "Jordão L, Constantino L and Anes E.* . 2008. Formulation and activity of liposome encapsulated ß-lactam antibiotics in macrophages infected with mycobacteria. 8th virtual congress HIV-AIDS. http: //WWW.aidscongress.net/pdf/338.pdf, ISBN: 978-972-95977-7-0". In 8th virtual congress HIV-AIDS. 2008.
    Published
  8. KUHNEL, M; ANES, ELSA; GRIFFITHS, G. "Isolation of Latex Bead-and Mycobacteria-Containing Phagosomes. Ed J. Celis". In Cell Biology, 57-62. Elsevier, 2006.
    Published • 10.1016/b978-012164730-8/50080-0
Conference abstract
  1. Mandal, M; Pires, David; ANES, ELSA. "Development and characterisation of a 3D cell culture model of the tuberculosis granuloma". Paper presented in 18th International Congress of Immunology (IUIS 2023), Cape town, 2024.
    Accepted
Conference paper
  1. Constantino, Luis; Magalhães, Marta; Pais, João; Antoniuk, Olha; Freire, Raquel; Pires, David; Valente, Emilia; Testa, Bernard; ANES, ELSA. "Benzoic acid derivatives as prodrugs for the treatment of tuberculosis". 2021.
    Published • 10.3390/ecmc2021-11501
  2. Constantino, Luis; Pais, João; Policarpo, Margarida; Pires, David; Testa, Bernard; ANES, ELSA. "Fluoroquinolone derivatives in the treatment of Mycobacterium tuberculosis infection". 2021.
    Published • 10.3390/ecmc2021-11524
  3. Marta Filipa Simões; Luis Constantino; ANES, ELSA. "Simões M, Valente M, Gómez MJR, Anes E and Constantino L. 2008. Lipophilic pyrazinoic acid prodrugs active against M. tuberculosis.". Paper presented in 1º Encontro Nacional de Química terapêutica, 2008.
    Published
  4. ANES, ELSA. "Anes E, Kuenhel, M, Bos E, Moniz-Pereira J, Habermann A, and Griffiths G. 2003. Selected lipids can activate phagosome actin assembly and maturation leading to the growth arrest of pathogenic mycobacteria.". Paper presented in !º Congresso da Sociedade Portuguesa de Ciências Farmacêuticas, 2003.
    Published
  5. Luisa Jordão; Luis Constantino; ANES, ELSA. Corresponding author: ANES, ELSA. "Jordão L, Anes E, Constantino L. 2003. Avaliação da actividade antimicobacteriana do Imipenem na sobrevivência intracelular de M. avium. Comparação entre as formas livre e lipossomal do fármaco.". Paper presented in 1º Congresso da Sociedade Portuguesa de Ciências Farmacêuticas, 2003.
    Published
  6. Luisa Jordão; ANES, ELSA; Luis Constantino. Corresponding author: ANES, ELSA. "Jordão L, Constantino L, Anes E. 2003. Avaliação da actividade antimicobacteriana de combinações de amoxicilina e ácido clavulâmico e cefaloridina e ácido clavulâmico na sobrevivência intracelular de M. avium e M. tuberculosis. Comparação entre as formas livre e lipossomal do fármaco.". Paper presented in 1º Congresso da Sociedade Portuguesa de Ciências Farmacêuticas, 2003.
    Published
  7. Luisa Jordão; ANES, ELSA; Luis Constantino. Corresponding author: ANES, ELSA. "Jordão L, Anes E, Constantino L. 2003. Desenvolvimento e validação dum método de doseamento simultâneo de amoxicilina e ácido clavulâmico em plasma por HPLC". Paper presented in 1º Congresso da Sociedade Portuguesa de Ciências Farmacêuticas, 2003.
    Published
  8. ANES, ELSA; Moniz-Pereira J. "Anes E and Moniz-Pereira J.1998. Role of the integrase on the mycobacteriophage Ms6 site-specific recombination event". Paper presented in 19th Meeting of the European Society of Mycobacteriologists, Lisbon, Portugal, 1998.
    Published
Conference poster
  1. Silveiro, C.; Olivença, Francisco; Nunes, Alexandra; ANES, ELSA; Catalão, Maria João. "CRISPRi-mediated depletion of distinctive PG modifications promotes beta-lactam hypersusceptibility phenotypes in M. tuberculosis". 2023.
  2. Delgado, Tiago; Pais, João; Estrada, Filipe GA; Rita Guedes; David Pires; ANES, ELSA; Constantino, Luis. "Development of New Drugs Based On The Dinitrobenzamide Scaffold To Combat the Menace of Tuberculosis". Paper presented in 14th iMed.ULisboa Postgraduate Students Meeting, 2023.
  3. Silveiro, C.; Marques, Mariana; Olivença, Francisco; Pires, David; ANES, ELSA. "The quest for novel targets in TB-therapy: CRISPRi-mediated repression of PG modifications in Mycobacterium smegmatis promotes beta-lactam susceptibility and intracellular killing". Paper presented in EMBO Workshop on Tuberculosis 2022, 2022.
  4. Delgado, Tiago; Pais, João; Estrada, Filipe GA; Rita Guedes ; David Pires; ANES, ELSA; Constantino, Luis. "Targeting pathogen cell wall biosynthesis to combat the menace of Tuberculosis". Paper presented in 2nd Chem & Biochem Students Meeting, 2022.
  5. Pais, João; Antoniuk, Olha; PIRES, DAVID; ANES, ELSA; Constantino, Luis. "Nitro derivatives of weak acids and the development of a new family of potential dprE1 inhibitors for the treatment of tuberculosis". Paper presented in XIII iMed.ULisboa Postgraduate Students Meeting, 2022.
  6. Delgado, Tiago; Pais, João; Estrada, Filipe GA; Rita Guedes ; David Pires; ANES, ELSA; Constantino, Luis. "Development of drugs based on the dinitrobenzamide scaffold for the treatment of tuberculosis, targeting pathogen cell wall biosynthesis". Paper presented in XIII iMed.ULisboa Postgraduate Students Meeting, 2022.
  7. Olivença, Francisco; Nunes, Alexandra; Macedo, Rita; Pires, David; Silveiro, Cátia; ANES, ELSA; João Paulo Gomes; Catalão, Maria João. "Decoding Beta-lactam Susceptibility Patterns in Mycobacterium tuberculosis Clinical Strains". Paper presented in 32nd European Congress of Clinical Microbiology and Infectious Diseases, 2022.
  8. Silveiro, Cátia; Mariana Marques; Olivença, Francisco; Pires, David; ANES, ELSA; Catalão, Maria João. Corresponding author: Catalão, Maria João. "A novel target in TB-therapy: the N-glycolylation of mycobacterial peptidoglycan contributes to antibiotic resistance and intracellular survival". Paper presented in MICROBIOTEC'21 - Congress of Microbiology and Biotechnology 2021, 2021.
  9. Olivença, Francisco; Pires, David; Nunes, Alexandra; Macedo, Rita; ANES, ELSA; Gomes, João Paulo. "Finding Key Genomic Markers of Beta-lactam Susceptibility in Clinical Isolates of Mycobacterium tuberculosis". Paper presented in MICROBIOTEC'21 - Congress of Microbiology and Biotechnology 2021, 2021.
  10. Silveiro, Cátia; Marques, Mariana; Carmo, Nuno; Olivença, Francisco; Pires, David; Ferreira, Claúdia; ANES, ELSA; Catalão, Maria João. Corresponding author: Catalão, Maria João. "Relevance of the N-glycolylation of mycobacterial peptidoglycan to antibiotic resistance and to host-pathogen interactions". Paper presented in iMed.ULisboa Meeting 2021, 2021.
  11. Machado, Diana; Pires, David; Perdigão, João; Ramos, Jorge; Couto, Isabel; Portugal, Isabel; ANES, ELSA; Viveiros, Miguel. "Efflux inhibitors against drug resistant Mycobacterium tuberculosis: antimicrobial agents and enhancers of macrophage killing activity". Paper presented in MicroBiotec13, 2013.
Encyclopedia entry
  1. José Miguel Azevedo Pereira; ANES, ELSA. Corresponding author: ANES, ELSA. "Main Consequences of Human Immunodeficiency Virus Infection". In E_Scholarly Community Encyclopedia, 2023. https://encyclopedia.pub/entry/history/show/97391.
    Published
  2. ANES, ELSA. Corresponding author: ANES, ELSA. "ESAT-6 a Major Virulence Factor of Mycobacterium tuberculosis". In Encyclopedia Scholarly Community, 2023. https://encyclopedia.pub/entry/history/show/103705.
    Published
Journal article
  1. João P. Pais; Olha Antoniuk; David Pires; Tiago Delgado; Andreia Fortuna; Paulo J. Costa; ANES, ELSA; Luis Constantino. Corresponding author: ANES, ELSA. "Synthesis, Activity, Toxicity, and In Silico Studies of New Antimycobacterial N-Alkyl Nitrobenzamides". Pharmaceuticals (2024): https://doi.org/10.3390/ph17050608.
    10.3390/ph17050608
  2. Tiago Delgado; João P. Pais; David Pires; Filipe G. A. Estrada; Rita C. Guedes; Elsa Anes; Luis Constantino. "Development of New Drugs to Treat Tuberculosis Based on the Dinitrobenzamide Scaffold". Pharmaceuticals (2024): https://doi.org/10.3390/ph17050559.
    10.3390/ph17050559
  3. Marta Calado; Rita Ferreira; David Pires; Quirina Santos-Costa; ANES, ELSA; Brites, Dora; Azevedo-Pereira, José Miguel. Corresponding author: Azevedo-Pereira, José Miguel. "Unraveling the Triad of Neuroinvasion, Neurodissemination, and Neuroinflammation of HIV-1 in the Central Nervous System". Reviews in Medical Virology e2534 (2024): 1-16. http://dx.doi.org/10.1002/rmv.2534.
    Open access • Published
  4. Francisco Olivença; David Pires; Cátia Silveiro; Bianca Gama; Frederico Holtreman; ANES, ELSA; Maria João Catalão. Corresponding author: ANES, ELSA. "Ethambutol and meropenem/clavulanate synergy promotes enhanced extracellular and intracellular killing of Mycobacterium tuberculosis". Antimicrobial Agents and Chemotherapy (2024): https://doi.org/10.1128/aac.01586-23.
    10.1128/aac.01586-23
  5. Marta Calado; David Pires; Carolina Conceição; Quirina Santos-Costa; Elsa Anes; José Miguel Azevedo-Pereira. "Human immunodeficiency virus transmission—Mechanisms underlying the cell-to-cell spread of human immunodeficiency virus". Reviews in Medical Virology (2023): https://doi.org/10.1002/rmv.2480.
    10.1002/rmv.2480
  6. Manoj Mandal; David Pires; Maria João Catalão; José Miguel Azevedo-Pereira; ANES, ELSA. Corresponding author: ANES, ELSA. "Modulation of Cystatin F in Human Macrophages Impacts Cathepsin-Driven Killing of Multidrug-Resistant Mycobacterium tuberculosis". Microorganisms (2023): https://doi.org/10.3390/microorganisms11071861.
    10.3390/microorganisms11071861
  7. ANES, ELSA; David Pires; Manoj Mandal; José Miguel Azevedo-Pereira. Corresponding author: ANES, ELSA. "ESAT-6 a Major Virulence Factor of Mycobacterium tuberculosis". Biomolecules (2023): https://doi.org/10.3390/biom13060968.
    10.3390/biom13060968
  8. Marta Calado; David Pires; Carolina Conceição; Rita Ferreira; Quirina Santos-Costa; Elsa Anes; José Miguel Azevedo-Pereira. "Cell-to-Cell Transmission of HIV-1 and HIV-2 from Infected Macrophages and Dendritic Cells to CD4+ T Lymphocytes". Viruses (2023): https://doi.org/10.3390/v15051030.
    10.3390/v15051030
  9. João P. Pais; Olha Antoniuk; Raquel Freire; David Pires; Emília Valente; ANES, ELSA; Luis Constantino. Corresponding author: ANES, ELSA. "Nitrobenzoates and Nitrothiobenzoates with Activity against M. tuberculosis". Microorganisms (2023): https://doi.org/10.3390/microorganisms11040969.
    10.3390/microorganisms11040969
  10. David Pires; Manoj Mandal; Ana I. Matos; Carina Peres; Maria João Catalão; José Miguel Azevedo-Pereira; Ronit Satchi-Fainaro; Helena F. Florindo; ANES, ELSA. Corresponding author: ANES, ELSA. "Development of Chitosan Particles Loaded with siRNA for Cystatin C to Control Intracellular Drug-Resistant Mycobacterium tuberculosis". Antibiotics (2023): https://doi.org/10.3390/antibiotics12040729.
    10.3390/antibiotics12040729
  11. Azevedo-Pereira, José Miguel; Pires, David; Calado, Marta; Mandal, Manoj; Santos-Costa, Quirina; ANES, ELSA. Corresponding author: ANES, ELSA. "HIV/Mtb Co-Infection: From the Amplification of Disease Pathogenesis to an “Emerging Syndemic”". Microorganisms 11 4 (2023): 853. http://dx.doi.org/10.3390/microorganisms11040853.
    Open access • 10.3390/microorganisms11040853
  12. Silveiro, Cátia; Marques, Mariana; Olivença, Francisco; Pires, David; Mortinho, Diana; Nunes, Alexandra; Pimentel, Madalena; Anes, Elsa; Catalão, Maria João. "CRISPRi-mediated characterization of novel anti-tuberculosis targets: Mycobacterial peptidoglycan modifications promote beta-lactam resistance and intracellular survival". Frontiers in Cellular and Infection Microbiology 13 (2023): http://dx.doi.org/10.3389/fcimb.2023.1089911.
    10.3389/fcimb.2023.1089911
  13. Santos, Filipa; Pires, David; ANES, ELSA; Rita C. Duarte, Ana. "INSIGHTS INTO THERAPEUTIC LIQUID MIXTURES AND FORMULATIONS TOWARDS TUBERCULOSIS THERAPY". International Journal of Pharmaceutics (2023): 122862. http://dx.doi.org/10.1016/j.ijpharm.2023.122862.
    10.1016/j.ijpharm.2023.122862
  14. David Pires; Manoj Mandal; Jacinta Pinho; Maria João Catalão; António José Almeida; José Miguel Azvedoereira; Maria Manuela Gaspar; ANES, ELSA. Corresponding author: ANES, ELSA. "Liposomal Delivery of Saquinavir to Macrophages Overcomes Cathepsin Blockade by Mycobacterium tuberculosis and Helps Control the Phagosomal Replicative Niches". International Journal of Molecular Sciences 24 2 (2023): 1142. https://doi.org/10.3390/ijms24021142.
    Open access • Published • https://doi.org/10.3390/ijms24021142
  15. Pais, João Pedro; Policarpo, Margarida; Pires, David; Francisco, Ana Paula; Madureira, Ana Margarida; Testa, Bernard; ANES, ELSA; Constantino, Luís. Corresponding author: ANES, ELSA. "Fluoroquinolone Derivatives in the Treatment of Mycobacterium tuberculosis Infection". Pharmaceuticals 15 10 (2022): 1213. http://dx.doi.org/10.3390/ph15101213.
    10.3390/ph15101213
  16. João P. Pais ; Marta Magalhães; Olha Antoniuk; Ivete Barbosa; Raquel Freire ; David Pires; Emília Valente ; et al. Corresponding author: ANES, ELSA. "Benzoic Acid Derivatives as Prodrugs for the Treatment of Tuberculosis". Pharmaceuticals 15 9 (2022): 1118. https://doi.org/10.3390/ph15091118.
    Open access • Published • doi.org/10.3390/ph15091118
  17. Morais, Diana; Tanoeiro, Luis; Marques, Andreia T. ; ANES, ELSA; Filipa F. Vale. Corresponding author: Filipa F. Vale. "Liposomal Delivery of Newly Identified Prophage Lysins in a Pseudomonas aeruginosa Model". Int. J. Mol. Sci. 23 17 (2022): 10143. https://www.mdpi.com/1422-0067/23/17/10143.
    Open access • Published • https://doi.org/10.3390/ijms231710143
  18. ANES, ELSA; Pires, David; Mandal, Manoj; Azevedo-Pereira, José Miguel. Corresponding author: ANES, ELSA. "Spatial localization of cathepsins: Implications in immune activation and resolution during infections". Frontiers in Immunology 13 (2022): http://dx.doi.org/10.3389/fimmu.2022.955407.
    Open access • Published • 10.3389/fimmu.2022.955407
  19. Francisco Olivença; Alexandra Nunes; Rita Macedo; David Pires; Cátia Silveiro; ANES, ELSA; Maria Miragaia; et al. "Uncovering Beta-Lactam Susceptibility Patterns in Clinical Isolates of Mycobacterium tuberculosis through Whole-Genome Sequencing". Microbiology Spectrum (2022): https://doi.org/10.1128/spectrum.00674-22.
    Open access • 10.1128/spectrum.00674-22
  20. Rai, Akhilesh; Ferrão, Rafaela; Palma, Paulo; Patricio, Tatiana; Parreira, Paula; ANES, ELSA; Tonda-Turo, Chiara; et al. "Antimicrobial peptide-based materials: opportunities and challenges". Journal of Materials Chemistry B 10 14 (2022): 2384-2429. http://dx.doi.org/10.1039/d1tb02617h.
    Open access • 10.1039/d1tb02617h
  21. Pires, David; Calado, Marta; Velez, Tomás; Mandal, Manoj; Catalão, Maria João; Neyrolles, Olivier; Lugo-Villarino, Geanncarlo; et al. Corresponding author: Anes, Elsa. "Modulation of Cystatin C in Human Macrophages Improves Anti-Mycobacterial Immune Responses to Mycobacterium tuberculosis Infection and Coinfection With HIV". Frontiers in Immunology 12 (2021): http://dx.doi.org/10.3389/fimmu.2021.742822.
    Open access • 10.3389/fimmu.2021.742822
  22. Filipa F. Vale; Jorge M.B. Vítor; Andreia T. Marques; José Miguel Azevedo-Pereira; ANES, ELSA; Joao Goncalves. "Origin, phylogeny, variability and epitope conservation of SARS-CoV-2 worldwide". Virus Research 304 (2021): 198526-198526. https://doi.org/10.1016/j.virusres.2021.198526.
    10.1016/j.virusres.2021.198526
  23. ANES, ELSA; Azevedo-Pereira, José Miguel; Pires, David. Corresponding author: ANES, ELSA. "Cathepsins and Their Endogenous Inhibitors in Host Defense During Mycobacterium tuberculosis and HIV Infection". Frontiers in Immunology 12 (2021): http://dx.doi.org/10.3389/fimmu.2021.726984.
    Open access • 10.3389/fimmu.2021.726984
  24. Pires, David; Valente, Sofia; Calado, Marta; Mandal, Manoj; Azevedo-Pereira, José Miguel; ANES, ELSA. Corresponding author: ANES, ELSA. "Repurposing Saquinavir for Host-Directed Therapy to Control Mycobacterium Tuberculosis Infection". Frontiers in Immunology 12 (2021): http://dx.doi.org/10.3389/fimmu.2021.647728.
    Open access • 10.3389/fimmu.2021.647728
  25. Pires, David; Bernard, Elliott M.; Pombo, João Palma; Carmo, Nuno; Fialho, Catarina; Gutierrez, Maximiliano Gabriel; Bettencourt, Paulo; ANES, ELSA. Corresponding author: ANES, ELSA. "Mycobacterium tuberculosis Modulates miR-106b-5p to Control Cathepsin S Expression Resulting in Higher Pathogen Survival and Poor T-Cell Activation". Frontiers in Immunology 8 (2017): http://dx.doi.org/10.3389/fimmu.2017.01819.
    10.3389/fimmu.2017.01819
  26. Pires, David; Marques, Joana; Pombo, João Palma; Carmo, Nuno; Bettencourt, Paulo; Neyrolles, Olivier; Lugo-Villarino, Geanncarlo; ANES, ELSA. Corresponding author: ANES, ELSA. "Role of Cathepsins in Mycobacterium tuberculosis Survival in Human Macrophages". Scientific Reports 6 1 (2016): http://dx.doi.org/10.1038/srep32247.
    10.1038/srep32247
  27. Bettencourt, Paulo; Pires, David; ANES, ELSA. Corresponding author: ANES, ELSA. "Immunomodulating microRNAs of mycobacterial infections". Tuberculosis 97 (2016): 1-7. http://dx.doi.org/10.1016/j.tube.2015.12.004.
    10.1016/j.tube.2015.12.004
  28. Machado, Diana; Pires, David; Perdigão, João; Couto, Isabel; Portugal, Isabel; Martins, Marta; Amaral, Leonard; ANES, ELSA; Viveiros, Miguel. Corresponding author: ANES, ELSA. "Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis". PLOS ONE 11 2 (2016): e0149326. http://dx.doi.org/10.1371/journal.pone.0149326.
    Open access • Published • 10.1371/journal.pone.0149326
  29. Pires, David; Valente, Emília; Simões, Marta Filipa; Carmo, Nuno; Testa, Bernard; Constantino, Luís; ANES, ELSA. Corresponding author: ANES, ELSA. "Esters of Pyrazinoic Acid Are Active against Pyrazinamide-Resistant Strains of Mycobacterium tuberculosis and Other Naturally Resistant Mycobacteria In Vitro and Ex Vivo within Macrophages". Antimicrobial Agents and Chemotherapy 59 12 (2015): 7693-7699. http://dx.doi.org/10.1128/aac.00936-15.
    10.1128/aac.00936-15
  30. Danilchanka, Olga; Pires, David; ANES, ELSA; Niederweis, Michael. Corresponding author: ANES, ELSA. "The Mycobacterium tuberculosis Outer Membrane Channel Protein CpnT Confers Susceptibility to Toxic Molecules". Antimicrobial Agents and Chemotherapy 59 4 (2015): 2328-2336. http://dx.doi.org/10.1128/aac.04222-14.
    10.1128/aac.04222-14
  31. Vibe, C.B.; Fenaroli, F.; Pires, D.; Wilson, S.R.; Bogoeva, V.; Kalluru, R.; Speth, M.; et al. "Thioridazine in PLGA nanoparticles reduces toxicity and improves rifampicin therapy against mycobacterial infection in zebrafish". Nanotoxicology (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84947285273&partnerID=MN8TOARS.
    10.3109/17435390.2015.1107146
  32. Danilchanka, O.; Pires, D.; Anes, E.; Niederweis, M.. Corresponding author: Anes, E.. "The mycobacterium tuberculosis outer membrane channel protein CpnT confers susceptibility to toxic molecules". Antimicrobial Agents and Chemotherapy 59 4 (2015): 2328-2336. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928902229&partnerID=MN8TOARS.
    10.1128/AAC.04222-14
  33. Luo, Xuan; Pires, David; Aínsa, José A.; Gracia, Begoña; Duarte, Noélia; Mulhovo, Silva; ANES, ELSA; Ferreira, Maria-José U.. Corresponding author: ANES, ELSA. "Zanthoxylum capense constituents with antimycobacterial activity against Mycobacterium tuberculosis in vitro and ex vivo within human macrophages". Journal of Ethnopharmacology 146 1 (2013): 417-422. http://dx.doi.org/10.1016/j.jep.2013.01.013.
    10.1016/j.jep.2013.01.013
  34. Bettencourt, Paulo; Marion, Sabrina; Pires, David; Santos, Leonor F.; Lastrucci, Claire; Carmo, Nuno; Blake, Jonathon; et al. Corresponding author: ANES, ELSA. "Actin-binding protein regulation by microRNAs as a novel microbial strategy to modulate phagocytosis by host cells: the case of N-Wasp and miR-142-3p". Frontiers in Cellular and Infection Microbiology 3 (2013): http://dx.doi.org/10.3389/fcimb.2013.00019.
    10.3389/fcimb.2013.00019
  35. Luo, X.; Pires, D.; Ainsa, J. A.; Gracia, B.; Duarte, N.; Mulhovo, S.; Anes, E.; Ferreira, M. J. U.. "In vitro and ex vivo antitubercular activity of compounds from Zanthoxylum capense". Planta Medica 78 11 (2012): 1110-1110. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000307042800346&KeyUID=WOS:000307042800346.
  36. Luo, X.; Pires, D.; Aínsa, J.A.; Gracia, B.; Mulhovo, S.; Duarte, A.; ANES, ELSA; Ferreira, M.-J.U.. "Antimycobacterial evaluation and preliminary phytochemical investigation of selected medicinal plants traditionally used in Mozambique". Journal of Ethnopharmacology 137 1 (2011): 114-120. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052034181&partnerID=MN8TOARS.
    10.1016/j.jep.2011.04.062
  37. Mishra, Bibhuti B.; Moura-Alves, Pedro; Sonawane, Avinash; Hacohen, Nir; Griffiths, Gareth; Moita, Luis F.; ANES, ELSA. Corresponding author: ANES, ELSA. "Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome". Cellular Microbiology 12 8 (2010): 1046-1063. http://dx.doi.org/10.1111/j.1462-5822.2010.01450.x.
    10.1111/j.1462-5822.2010.01450.x
  38. Anand, P.K.; Anand, E.; Bleck, C.K.E.; ANES, ELSA; Griffiths, G.. "Exosomal hsp70 induces a pro-inflammatory response to foreign particles including mycobacteria". PLoS ONE 5 4 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77956314712&partnerID=MN8TOARS.
    10.1371/journal.pone.0010136
  39. Prakash, H.; Lüth, A.; Grinkina, N.; Holzer, D.; Wadgaonkar, R.; Gonzalez, A.P.; ANES, ELSA; Kleuser, B.. "Sphingosine kinase-1 (SphK-1) regulates Mycobacterium smegmatis infection in macrophages". PLoS ONE 5 5 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77956295892&partnerID=MN8TOARS.
    10.1371/journal.pone.0010657
  40. Pires, D.; Bettencourt, P.; Carmo, N.; Bergant, T.; Jordao, L.; ANES, ELSA. Corresponding author: ANES, ELSA. "Interference of mycobacterium tuberculosis with the endocytic pathways on macrophages and dendritic cells from healthy donors: role of cathepsins". Drug Discovery Today 15 23-24 (2010): 1112-1112. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000285235700096&KeyUID=WOS:000285235700096.
    10.1016/j.drudis.2010.09.436
  41. Pires, D.; Bettencourt, P.; Carmo, N.; Niederweis, M.; Anes, E.. "Role of mycobacterium tuberculosis outermembrane porins in bacterial survival within macrophages". Drug Discovery Today 15 23-24 (2010): 1112-1113. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000285235700097&KeyUID=WOS:000285235700097.
    10.1016/j.drudis.2010.09.437
  42. Simões, Marta Filipa; Valente, Emília; Gómez, M. José Rodríguez; ANES, ELSA; Constantino, Luís. Corresponding author: ANES, ELSA. "Lipophilic pyrazinoic acid amide and ester prodrugs". European Journal of Pharmaceutical Sciences 37 3-4 (2009): 257-263. http://dx.doi.org/10.1016/j.ejps.2009.02.012.
    10.1016/j.ejps.2009.02.012
  43. Fabrino, D.L.; Bleck, C.K.E.; ANES, ELSA; Hasilik, A.; Melo, R.C.N.; Niederweis, M.; Griffiths, G.; Gutierrez, M.G.. "Porins facilitate nitric oxide-mediated killing of mycobacteria". Microbes and Infection 11 10-11 (2009): 868-875. http://www.scopus.com/inward/record.url?eid=2-s2.0-68949141676&partnerID=MN8TOARS.
    10.1016/j.micinf.2009.05.007
  44. Gutierrez, M.G.; Gonzalez, A.P.; ANES, ELSA; Griffiths, G.. "Role of lipids in killing mycobacteria by macrophages: Evidence for NF-¿B-dependent and -independent killing induced by different lipids". Cellular Microbiology 11 3 (2009): 406-420. http://www.scopus.com/inward/record.url?eid=2-s2.0-59849086846&partnerID=MN8TOARS.
    10.1111/j.1462-5822.2008.01263.x
  45. Kuehnel, M.P.; Rybin, V.; Anand, P.K.; ANES, ELSA; Griffiths, G.. "Lipids regulate P2X7-receptor-dependent actin assembly by phagosomes via ADP translocation and ATP synthesis in the phagosome lumen". Journal of Cell Science 122 4 (2009): 499-504. http://www.scopus.com/inward/record.url?eid=2-s2.0-64849108009&partnerID=MN8TOARS.
    10.1242/jcs.034199
  46. ANES, ELSA; Jordao, L.. Corresponding author: ANES, ELSA. "Trick-or-Treat: Dietary Lipids and Host Resistance to Infectious Disease". Mini-Reviews in Medicinal Chemistry 8 14 (2008): 1452-1458. http://dx.doi.org/10.2174/138955708786786525.
    10.2174/138955708786786525
  47. Jordao, Luisa; Lengeling, Andreas; Bordat, Yann; Boudou, Frederic; Gicquel, Brigitte; Neyrolles, Olivier; Becker, Pablo D.; et al. Corresponding author: ANES, ELSA. "Effects of omega-3 and -6 fatty acids on Mycobacterium tuberculosis in macrophages and in mice". Microbes and Infection 10 12-13 (2008): 1379-1386. http://dx.doi.org/10.1016/j.micinf.2008.08.004.
    10.1016/j.micinf.2008.08.004
  48. Gutierrez, M.G.; Mishra, B.B.; Jordao, L.; Elliott, E.; ANES, ELSA; Griffiths, G.. "NF-¿B activation controls phagolysosome fusion-mediated killing of mycobacteria by macrophages". Journal of Immunology 181 4 (2008): 2651-2663. http://www.scopus.com/inward/record.url?eid=2-s2.0-53149144336&partnerID=MN8TOARS.
  49. Jordao, L.; Simoes, M.; Bleck, C.; Griffiths, G.; ANES, ELSA. Corresponding author: ANES, ELSA. "Characterization of mycobacterium bovis phagosome". Microscopy and Microanalysis 14 SUPPL. 3 (2008): 124-125. http://www.scopus.com/inward/record.url?eid=2-s2.0-53349142051&partnerID=MN8TOARS.
    10.1017/S1431927608089629
  50. Kühnel, M.; Mayorga, L.S.; Dandekar, T.; Thakar, J.; Schwarz, R.; ANES, ELSA; Griffiths, G.; Reich, J.. "Modelling phagosomal lipid networks that regulate actin assembly". BMC Systems Biology 2 (2008): http://www.scopus.com/inward/record.url?eid=2-s2.0-61349116272&partnerID=MN8TOARS.
    10.1186/1752-0509-2-107
  51. ANES, ELSA; Jordao, L.. Corresponding author: ANES, ELSA. "Trick-or-treat: dietary lipids and host resistance to infectious disease.". Mini reviews in medicinal chemistry 8 14 (2008): 1452-1458. http://www.scopus.com/inward/record.url?eid=2-s2.0-61549116265&partnerID=MN8TOARS.
  52. Jordao, Luisa; Bleck, Christopher K. E.; Mayorga, Luis; Griffiths, Gareth; ANES, ELSA. Corresponding author: ANES, ELSA. "On the killing of mycobacteria by macrophages". Cellular Microbiology 0 0 (2007): 071106215315001-???. http://dx.doi.org/10.1111/j.1462-5822.2007.01067.x.
    10.1111/j.1462-5822.2007.01067.x
  53. Barata, Z.; Soares, N.; Ferreira, M. J. U.; Duarte, A.; Silva, A. N.; Anes, E.; Mulhovo, S.; AM, Madureira. "Screening for antimycobacterial activity of plants used in traditional medicine". Planta Medica 73 9 (2007): 873-874. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000249395900242&KeyUID=WOS:000249395900242.
  54. Treede, I.; Braun, A.; Sparla, R.; Kühnel, M.; Giese, T.; Turner, J.R.; ANES, ELSA; et al. "Anti-inflammatory effects of phosphatidylcholine". Journal of Biological Chemistry 282 37 (2007): 27155-27164. http://www.scopus.com/inward/record.url?eid=2-s2.0-34848879554&partnerID=MN8TOARS.
    10.1074/jbc.M704408200
  55. ANES, ELSA; Peyron, Pascale; Staali, Leila; Jordao, Luisa; Gutierrez, Maximiliano G.; Kress, Holger; Hagedorn, Monica; et al. "Dynamic life and death interactions between Mycobacterium smegmatis and J774 macrophages". Cellular Microbiology 8 6 (2006): 939-960. http://dx.doi.org/10.1111/j.1462-5822.2005.00675.x.
    10.1111/j.1462-5822.2005.00675.x
  56. Kalamidas, S.A.; Kuehnel, M.P.; Peyron, P.; Rybin, V.; Rauch, S.; Kotoulas, O.B.; Houslay, M.; et al. "cAMP synthesis and degration by phagosomes regulate actin assembly and fusion events: Consequences for mycombacterial". Journal of Cell Science 119 17 (2006): 3686-3694. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749410753&partnerID=MN8TOARS.
    10.1242/jcs.03091
  57. Castandet, J.; Prost, J.-F.; Peyron, P.; Astarie-Dequeker, C.; ANES, ELSA; Cozzone, A.J.; Griffiths, G.; Maridonneau-Parini, I.. "Tyrosine phosphatase MptpA of Mycobacterium tuberculosis inhibits phagocytosis and increases actin polymerization in macrophages". Research in Microbiology 156 10 (2005): 1005-1013. http://www.scopus.com/inward/record.url?eid=2-s2.0-28444483606&partnerID=MN8TOARS.
    10.1016/j.resmic.2005.05.013
  58. ANES, ELSA; Kühnel, Mark Philipp; Bos, Evelyne; Moniz-Pereira, Jose; Habermann, Anja; Griffiths, Gareth. "Selected lipids activate phagosome actin assembly and maturation resulting in killing of pathogenic mycobacteria". Nature Cell Biology 5 9 (2003): 793-802. http://dx.doi.org/10.1038/ncb1036.
    Published • 10.1038/ncb1036
  59. Freitas-Vieira, A.; ANES, ELSA; Moniz-Pereira, J.. "The site-specific recombination locus of mycobacteriophage Ms6 determines DNA integration at the tRNA(Ala) gene of Mycobacterium spp.". Microbiology 144 12 (1998): 3397-3406. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032427916&partnerID=MN8TOARS.
  60. ANES, ELSA; Portugal, I.; Moniz-Pereira, J.. "Insertion into the Mycobacterium smegmatis genome of the aph gene through lysogenization with the temperate mycobacteriophage Ms6". FEMS Microbiology Letters 95 1 (1992): 21-25. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026905677&partnerID=MN8TOARS.
    10.1016/0378-1097(92)90731-3
  61. Portugal, I.; ANES, ELSA; Moniz-Pereira, J.. "Temperate mycobacteriophage from M. smegmatis". Acta Leprologica 7 SUPPL. 1 (1989): 243-244. http://www.scopus.com/inward/record.url?eid=2-s2.0-0024386581&partnerID=MN8TOARS.
Preprint
  1. Tiago Delgado; João Pais; David Pires; Filipe Estrada; Rita Guedes; Elsa Anes; Luís Constantino. "Development of New Drugs to Treat Tuberculosis Based on the Dinitrobenzamide Scaffold". 2024. https://doi.org/10.20944/preprints202403.0811.v1.
    10.20944/preprints202403.0811.v1
  2. Manoj Mandal; David Pires; Marta Calado; José Miguel Azevedo-Pereira; ANES, ELSA. Corresponding author: ANES, ELSA. "Cystatin F Depletion in Mycobacterium tuberculosis-Infected Macrophages Improves Cathepsin C/Granzyme B-driven Cytotoxic Effects on HIV-Infected Cells during Coinfection.". 2024. https://www.preprints.org/manuscript/202403.1773/v1.
  3. João Pedro Pais; Olha Antoniuk; David Pires; Tiago Delgado; Andreia Fortuna; Paulo J Costa; Elsa Anes; Luis Constantino. "Synthesis, Activity, Toxicity, and In Silico Studies of New Antimycobacterial N-alkyl Nitrobenzamides as Potential DprE1 Inhibitors". 2024. https://doi.org/10.20944/preprints202404.1152.v1.
    10.20944/preprints202404.1152.v1
  4. Elsa Anes; David Pires; Manoj Mandal; José Miguel Azevedo-Pereira. "ESAT-6 a Major Virulence Factor of Mycobacterium tuberculosis and a Target for New Therapeutic Interventions". 2023. https://doi.org/10.20944/preprints202305.0979.v1.
    10.20944/preprints202305.0979.v1
  5. Elsa Anes; David Pires; Manoj Mandal; José Miguel Azevedo-Pereira. "ESAT-6 a Major Virulence Factor of Mycobacterium tuberculosis and a Target for New Therapeutic Interventions". 2023. https://doi.org/10.20944/preprints202305.0979.v2.
    10.20944/preprints202305.0979.v2
  6. Francisco Olivença; David Pires; Cátia Silveiro; Bianca Gama; Frederico Holtreman; Elsa Anes; Maria João Catalão. "Ethambutol and Meropenem/Clavulanate Synergy Promotes Enhanced Extracellular and Intracellular Killing ofMycobacterium tuberculosis". 2023. https://doi.org/10.1101/2023.10.24.563807.
    10.1101/2023.10.24.563807
  7. Filipa F Vale; Jorge M.B. Vítor; Andreia T. Marques; José Miguel Azevedo-Pereira; Elsa Anes; João Gonçalves. "Origin, Phylogeny, Variability and Epitope Conservation of SARS-CoV-2 Worldwide". 2021. https://doi.org/10.20944/preprints202105.0750.v1.
    10.20944/preprints202105.0750.v1

Artistic / Performance

Visual artwork
  1. ANES, ELSA; Paulo Anes; Manuel Peres. Parto de Fé. ed Caravela 2019, ISBN9789895433001.

Intellectual property

Patent
  1. ANES, ELSA. 2022. "Luis Filipe Vicente Constantino, João Pedro Almeida Pais, Tiago Alexandre Duarte Delgado, Olha Antoniuk, Raquel Martins Da Silva, Elsa Maria Ribeiro Dos Santos Anes, David Alexandre Rodrigues Pires. (2022). NITROBENZAMIDE COMPOUNDS, METHODS AND USES THEREOF (European Patent Application nr EP22199255) European Patent Office.".
    Granted/Issued
  2. ANES, ELSA. 2022. "Luis Filipe Vicente Constantino, João Pedro Almeida Pais, Tiago Alexandre Duarte Delgado, Olha Antoniuk, Elsa Maria Ribeiro Dos Santos Anes, David Alexandre Rodrigues Pires. (2022). BENZOIC ACID DERIVATIVES, METHODS AND USES THEREOF. (European Patent Application nr EP22199251) European Patent Office.".
    Granted/Issued
  3. João Nunes; ANES, ELSA; José Miguel Azevedo-Pereira. 2022. "Air quality enhancement system based on fluid mechanics and integrated uv emission. Application filed by Associação BLC3 - Campus de Tecnologia e Inovação, Universidade De Coimbra, Universidade Do Minho, Faculdade De Farmácia Da Universidade De Lisboa PCT/IB2021/057430".
    Granted/Issued
  4. ANES, ELSA; João Nunes; José Miguel Azevedo-Pereira; Quirina Santos Costa; David Pires. 2020. "Sistema de mecânica de fluidos e emissão integrada de UV. Patente Portuguesa". Portugal.
    Granted/Issued
  5. ANES, ELSA; Luis Filipe Constantino; Emilia valente; Marta Filipa Simões. 2017. "Pró-fármacos de ácidos orgânicos e composições farmacêuticas contendo os referidos pró-fármacos". Portugal.
    Granted/Issued
  6. ANES, ELSA. 2013. "Pyrazinoic Acid Prodrugs activated by Esterases of Mycobacteria. WO2013084214".
    Granted/Issued
  7. Constantino, Luis; ANES, ELSA; Emilia Valente; Marta Filipa Simões. 2013. "Vesicular formulations containing organic acid prodrugs, process for their preparation. Euroasian Patent Organization – Euroasian Office". Rússia.Concedida/Emitida".
  8. Constantino, Luis; ANES, ELSA; Emilia Valente; Marta Filipa Simões. 2013. "Vesicular formulations containing organic acid prodrugs, process for their preparation". China. Concedida/Emitida". China.
    Granted/Issued
  9. ANES, ELSA. 2007. "Vesicular formulations containing organic acid prodrugs, process for their preparation, new prodrugs, pharmaceutical compositions and method for the treatment of tuberculosis and other mycobacteriosis". Portugal.
  10. ANES, ELSA. 1999. "DNA Integration into Mycobacterium spp. genome by trans-complementation using a site-specific integration system WO 1999007861 A1.Moniz-Pereira J, Anes E, Vieira A, Garcia M and Alves P".
Provisional application for patent
  1. 2023. "Compostos tioesteres, métodos de obtenção e seu uso. Pedido de Patente 118464). Instituto Nacional de Propriedade Industrial (INPI).Luis Filipe Vicente Constantino, João Pedro Almeida Pais, Olha Antoniuk, Duarte Manuel Moura da Silva Figueiredo Antunes, Tiago Alexandre Duarte Delgado, Elsa Maria Ribeiro Dos Santos Anes, David Alexandre Rodrigues Pires.".
    Protected
  2. 2022. "Luis Filipe Vicente Constantino, João Pedro Almeida Pais, Tiago Alexandre Duarte Delgado, Olha Antoniuk, Elsa Maria Ribeiro Dos Santos Anes, David Alexandre Rodrigues Pires. (2022). BENZOIC ACID DERIVATIVES, METHODS AND USES THEREOF. (Pedido Provisório de Patente 118234). Instituto Nacional de Propriedade Industrial (INPI).".
    Protected
  3. 2022. "Luis Filipe Vicente Constantino, João Pedro Almeida Pais, Tiago Alexandre Duarte Delgado, Olha Antoniuk, Raquel Martins Da Silva, Elsa Maria Ribeiro Dos Santos Anes, David Alexandre Rodrigues Pires. (2022). NITROBENZAMIDE COMPOUNDS, METHODS AND USES THEREOF (Pedido Provisório de Patente 118236). Instituto Nacional de Propriedade Industrial (INPI).".
    Protected
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/07 Mandal M., Calado M. Azevedo-Pereira JM., Pires D. and Anes E. Manipulation of protease inhibitors for developing therapeutic strategies against Mycobacterium tuberculosis infection (OC10). 13th iMed.ULisboa Postgraduate Students Meeting 13th iMed.ULisboa Postgraduate Students Meeting
iMed.ULisboa (Portugal)
2022/04 Olivença F, Pires D, Silveiro C, R., Anes E, Catalão MJ. Ethambutol and meropenem/clavulanic acid synergy promotes extracellular and intracellular killing of Mycobacterium tuberculosis, ECCMID 2022- European Congress of Clinical Microbiology and Infectious Diseases, 23-26 April 2022, Lisbon, Portugal. ECCMID 2022- European Congress of Clinical Microbiology and Infectious Diseases
(Lisboa, Portugal)
2022/03/11 Elsa Anes. Imunopatogénese na infeção HIV. Primeira Reunião SPFCS sobre Infecciologia Infeção por HIV. As novidades da outra pandemia. Primeira Reunião SPFCS sobre Infecciologia Infeção por HIV. As novidades da outra pandemia
Sociedade Portuguesa de Farmacêuticos em Cuidados de Saúde (Évora, Portugal)
2021/11/03 Marta Magalhães, João Pais, Olha Antoniuk, Raquel Freire, David Pires , Emilia Valente , Bernard Testa, Elsa Anes, Luis Constantino*. Benzoic acid derivatives as prodrugs for the treatment of tuberculosis. 7th International Electronic Conference on Medicinal Chemistry session Round table on infectious diseases, 03 November 2021.  Published by MDPI https://doi.org/10.3390/ECMC2021-11501 7th International Electronic Conference on Medicinal Chemistry session Round table on infectious diseases
(Portugal)
2021/11/03 João Pais, Margarida Policarpo, David Pires, Bernard Testa, Elsa Anes, Luis Constantino*. Fluoroquinolone derivatives in the treatment of mycobacterium tuberculosis infection. 7th International Electronic Conference on Medicinal Chemistry session Round table on infectious diseases, 03 November 2021.  Published by MDPI. https://doi.org/10.3390/ECMC2021-11524   7th International Electronic Conference on Medicinal Chemistry session Round table on infectious diseases
2021/07/23 Elsa Anes The host pathogen Interactions Unit. Post graduated students iMedUlisboa 2021 meeting Post graduated students iMedUlisboa 2021 meeting
2020/11/14 Elsa Anes Mtb-HIV co-infection a dangereus relationship. 36º congresso sociedade portuguesa de pneumologia 12-14 nov 2020 36º congresso sociedade portuguesa de pneumologia
sociedade portuguesa de pneumologia
2020/01/31 Pires, D, Valente S and Anes E. Manipulation of host lysosomal cathepsins to control mycobacteria infection in human macrophages II Simpósio de Investigação em Tuberculose e Micobactérias Não Tuberculosas em Portugal II Simpósio de Investigação em Tuberculose e Micobactérias Não Tuberculosas em Portugal 31 de janeiro de 2020, , Lisboa, Portugal
Faculdade de Farmácia da Universidade de Lisboa (Portugal)
2020/01/31 Olivença, F., Pires, D., Carmo, N., Macedo, R., Nunes, A., Gomes, J. P., Anes, E., Catalão, M. J. “Inhibition of Peptidoglycan Biosynthesis as a Strategy against Drug-resistant Mycobacterium tuberculosis”. II Simpósio de Investigação em Tuberculose e Micobactérias Não Tuberculosas em Portugal 31 de janeiro de 2020, Faculdade de Farmácia da Universidade de Lisboa, Lisboa, Portugal II Simpósio de Investigação em Tuberculose e Micobactérias Não Tuberculosas em Portugal
Universidade de Lisboa Faculdade de Farmácia
2019/11/27 Elsa Anes. Exploring innate immunity as Host Directed Therapeutic strategies for tuberculosis and HIV co-infection, Cardiff School of Pharmacy Seminar series, Wales, 2019, 27 nov Cardiff School of Pharmacy Seminar series
Arwyn Tommos Jones, University of Cardiff
2019/11/22 Exploring innate immunity as Host Directed Therapeutic strategies for tuberculosis and HIV co-infection, III Jornadas de Microbiologia e Biologia Molecular, Inst Egas Moniz III Jornadas de Microbiologia e Biologia Molecular, Inst Egas Moniz
Instituto Egas Moniz (Portugal)
2019/03/25 Elsa Anes. Co-infeção HIV- M. tuberculosis um relacionamento perigoso. I Simposio Dia Mundial da Tuberculose FFUL, SPP, SPDIMC I Simposio Dia Mundial da Tuberculose FFUL, SPP, SPDIMC
FFUL, SPP, SPDIMC (Portugal)
2019/03/14 Elsa Anes. Discovering, validating and exploiting novel host targed based treatments for tuberculosis. X Jornadas Nacionais de Ciências Biomédicas Aveiro X Jornadas Nacionais de Ciências Biomédicas
Universidade de Aveiro (Portugal)
2018/10/26 Anes E. 2018 HIV- Tuberculosis co-infection. V Congresso Nacional de Virologia, Porto V Congresso Nacional de Virologia, Porto
Sociedade Portuguesa de Virologia (Portugal)
2018/07/04 Anes E, Pires D Searching the mycobacterial phagosome for host-targeted therapeutics for tuberculosis Encontro Ciência 18. FCT, Lisboa(1400-550-A2-4) Encontro com a Ciência e tecnologia em Portugal
FCT (Portugal)
2018/06/18 Elsa Anes Exploring innate immunity for HDT Primeiro simpósio de investigação em tuberculose e micobactérias não tuberculosas em Portugal 18.6.2018 Coimbra Primeiro simpósio de investigação em tuberculose e micobactérias não tuberculosas em Portugal
Universidade de Coimbra
2018/05/08 Anes E. Mycobacterium tuberculosis Modulates miR-106b-5p to Control Cathepsin S Expression Resulting in Higher Pathogen Survival and Poor T-Cell Activation. Janssen Innovation2018 , Oporto Portugal. Jansen Innovation2018
Janssen (Porto, Portugal)
2018/04/07 Anes E. 2018 Host directed therapies for tuberculosis Science talks: tuberculosis April 2018 Science talks: tuberculosis
AEFFUL
2018/04/04 Pires D, Fialho AC and Anes E. 2018 Cathepsins, endocytic pathways and the role of miRNAs: implications in TB control Science talks: tuberculosis April 2018 Science talks: tuberculosis
AEFFUL
2017/05/05 Azevedo-Pereira JM, Anes E. Oral communication. HIV Research in Portugal: what we already do, how we can do more.Workshop Fórum Janssen Innovation'17, Cascais Pt. Workshop Fórum Jansen Innovation'17, Cascais Pt.
Janssen (Cascais, Portugal)
2017 Anes E. Discovering, validating and exploiting novel host target-based treatments for tuberculosis. Symposia The Janssen Commemorative Session of World’s TB Day Symposia The Janssen Commemorative Session of World’s TB Day
Janssen (Portugal)
2016/10/23 Anes. E.Role of Cathepsins in Mycobacterium tuberculosis Survival Within Human Macrophages. Jansen Innovation 2016 Jansen Innovation 2016
Jansen (Lisboa, Portugal)
2016/09/19 Elsa Anes, Pires D. To Control or to be Controlled: Role of Cathepsins in Mycobacterium tuberculosis Survival Within Human Macrophages Cell Symposia: 100 years of phagocytes, Cell press19-22 September | Sicily, Italy Cell Symposia: 100 years of phagocytes, Sicily, Italy
Cell Press editorial group (Sicilia)
2016/07/25 Pires D, Valente E, Simões MF, Carmo N, Testa B, Constantino L, and Anes E. “Esters of Pyrazinoic Acid Are Active against Pyrazinamide-Resistant Strains of Mycobacterium tuberculosis and Other Naturally Resistant Mycobacteria In Vitro and Ex Vivo within Macrophages” “8th iMed.UL Postgraduate Students Meeting”, 2016, Lisbon, Portugal 8th iMed.UL Postgraduate Students Meeting
iMed.UL Postgraduate Students
2015/12/05 Machado D, Pires D, Perdigão J, Ramos J, Couto I, Portugal I, Anes E and Viveiros M. Oral and poster communication “Efflux inhibitors against drug resistant Mycobacterium tuberculosis: antimicrobial agents and enhancers of macrophage killing activity”6th joint congress of Microbiology and Biotechnology: Microbiotec15, Évora, Portugal 6th joint congress of Microbiology and Biotechnology: Microbiotec15
Sociedade Portuguesa de Microbiologia
2014/11/18 Anes E. “Legionella an ambiental microorganism, an accidental pathogen” First Symposia Associação Nacional das Farmácias Ébola e Doença do Legionário Centro de Congressos de Lisboa,2014, 18 Novembro, Lisboa (OC). First Symposia Associação Nacional das Farmácias Ébola e Doença do Legionário
Associação Nacional das Farmácias
2014 Elsa Anes. 2014 “Discovering, validating and exploiting novel host target-based treatments for tuberculosis”. Oporto workshop on nanodelivery systems, FFUP. Oporto workshop on nanodelivery systems,
Universidade do Porto faculdade de Farmácia (Porto, Portugal)
2012/10/13 Anes E. Molecular mechanisms for immunomodulation and immunoresistance in Mycobacterium spp infection . VII Congresso da Sociedade Portuguesa de Ciências Veterinárias, Oct 13-15, Vale de Santarém V Congresso da Sociedade Portuguesa de Ciências Veterinárias
Sociedade Portuguesa de Ciências Veterinárias
2012/09/20 Anes E. Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome. XXXVIII Annual Meeting of the Portuguese Society for Immunology Fighting Intracellular Pathogens: from bench to bedside, Braga, September 20-22. XXXVI Annual Meeting of the Portuguese Society for Immunology Fighting Intracellular Pathogens: from bench to bedside
Portuguese Society for Immunology
2012/09/10 Anes E. Interaction of Mycobacterium tuberculosis with macrophages, modulation of cytoskeleton and the inflammasome.Institut Pasteur seminar series, Paris,Fr. Host Brigitte Gicquel Institute Pasteur seminar series, Paris
Brigitte Gicquel (Paris, France)
2012/07/19 Anes E. 2012. Discovering, validating and exploiting novel host target-based treatments for tuberculosis.Amsterdam. Amesterdam Meeting on New combinatorial Medicine for Tuberculosis: for a SME-targeted Collaborative Project. Host Olivier Neyrolles Amesterdam Meeting on New combinatorial Medicine for Tuberculosis: for a SME-targeted Collaborative Project
SME-targeted Collaborative Project
2010/12/01 Anes E. The human macrophage and the killing mechanisms for mycobacteria. European Science Foundation EMRC Exploratory Workshop EW09-007 Multi-disciplinary consortium for the development of effective, but non-toxic drugs against MDR-TB and XDR-TB, Lisboa, Portugal, December 1-3. European Science Foundation EMRC Exploratory Workshop EW09-007
Multi-disciplinary consortium for the development of effective, but non-toxic drugs against MDR-TB and XDR-TB (Lisboa, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2021/11/02 - Current Developing host-directed-therapies for Mycobacterium tuberculosis infection and HIV co-infection based on Cystatins manipulation. PhD Supervision of the student Manoj Mandal.
Supervisor of Manoj Mandal
Doutoramento (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/07/01 - 2024/03/08 Decoding the Peptidoglycan Patterns Associated with Beta-lactams Susceptibility and Host Immune Recognition in Drugresistant Mycobacterium tuberculosis . PhD co-Supervision of the student Francisco Olivença
Co-supervisor of Francisco Olivença Miguel
Doutoramento (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/01/06 - 2023/11/06 Tuberculose no século 21
Supervisor of Tiago Alexandre Goulart Da Silva
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 - 2021 New therapeutic approaches to treat Tuberculosis. ERASMUS Uniwersytet Wroclawski, Polónia; Master, EQF level 7
Supervisor of Joanna Ukzo,
Mestrado (Master)
Uniwersytet Wroclawski, Poland
2021 - 2021 Imunopatologia no Covid-19
Supervisor of Ana Margarida Soares Reis Bagorro
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 - 2021 Vitamina D no combate às infeções
Supervisor of Ângela Rodrigues Cardoso
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 - 2021 Role of Cystatin C in HIV-1 Infection of Human Macrophages. Trabalho de investigação desenvolvido em laboratório.
Supervisor of Tomás Serra Velez
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 - 2020 Melanossomas e tráfego de vesículas na pigmentação da pele e cabelo. Estratégias no controlo da pigmentação
Supervisor of Catarina Alexandra Alcobaça Sousa
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 - 2020 Infeções urinárias recorrentes: relação hospedeiro-patogeno
Supervisor of Inês Margarida Alves de Jesus
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 - 2020 Acne: relação hospedeiro-patogeno
Supervisor of Marta Sofia Silva Santos
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - 2019 Infeções Urinárias Repetidas Relação Hospedeiro-Patogeno
Supervisor of • Raquel de Oliveira Simões
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - 2019 Acne: relação hospedeiro-patogeno
Supervisor of • Cátia Joceline Silva Moreira
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - 2019 Melanossomas e tráfego de vesículas
Supervisor of Carolina Lucas Guedes Guimarães
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - 2019 Deorphanization of receptors: Applying screening techniques to two orphan GPCRs
Supervisor of Ana Catarina Rufas da Silva Santos
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 - 2019 Identification and Manipulation of Cystatins to Control Mycobacterium tuberculosis Infection of Human Macrophages. Mestrado de Microbiologia Aplicada, FC-Ulisboa
Co-supervisor of Sofia Valente
Mestrado em Microbiologia Aplicada (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2018 - 2018 Tuberculose
Supervisor of João Filipe Marques Aparício
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 - 2018 Legionella pneumophila um patogeno acidental
Supervisor of Rui Filipe Nunes Padeiro
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 - 2018 Acne: relação hospedeiro patogeno
Supervisor of Mariana Prata Aires Simões
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017 - 2018 Identification and characterization of host cathepsins and cystatins during tuberculosis and HIV co-infection of antigen presenting cells. Mestrado em Ciências Biofarmaceuticas FFULisboa
Supervisor of Ana Catarina Fialho
Mestrado em Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015 - 2015 Imunidade inata na tuberculose. http://hdl.handle.net/10451/26857
Supervisor of Zuleica Rodrigues Delact Mendes
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015 - 2015 Tuberculose. http://hdl.handle.net/10451/26951
Supervisor of Ana Teresa Barradas de Carvalho,
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015 - 2015 Co-infeção Vírus da Imunodeficiência Humana - Mycobacterium tuberculosis. http://hdl.handle.net/10451/27006
Supervisor of Sheniz Munir Amir Ali Ibraimo,
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015 - 2015 Legionelose. http://hdl.handle.net/10451/27119
Supervisor of Mafalda Margarida Pereira de Vasconcelos
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015 - 2015 Salmonelose. http://hdl.handle.net/10451/26965
Supervisor of Sara Isabel Serra Martins Nogueira Cortiço
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014 - 2015 “La protéine Rab27A et son rôle dans le processus de phagocytose chez les macrophages" Master en Chimie et Biologie, Univ. Strasbourg.
Supervisor of Camille Grossholtz
Master en Chimie et Biologie, Univ. Strasbourg. (Master)
Université de Strasbourg, France
2010/09/01 - 2014/12/06 Interference of Mycobacterium tuberculosis with the endocytic/ antigen presentation pathways on macrophages and dendritic cells. PhD Supervision of the student David Pires
Supervisor of David Pires
Doutoramento (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2010/09/01 - 2014/06/06 Human factors involved in Mycobacterium tuberculosis infection. The role of host vesicular traffic genes. PhD Supervision of the student Nuno Baltazar do Carmo
Supervisor of Nuno Baltazar Carmo
Doutoramento (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014 - 2014 Imunidade Inata na Tuberculose. http://hdl.handle.net/10451/26744
Supervisor of Joana Filipa Coutinho do Nascimento Almeida
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2013 - 2014 Manipulation of cystein cathepsins during Mycobacterium tuberculosis infection of human macrophages" Mestrado em Microbiologia Aplicada. Faculdade de Ciências da Universidade de Lisboa.
Supervisor of João Palma Pombo
Mestrado emMicrobiologia Aplicada (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2013 - 2014 Mycobacteria manipulation of host proteases and inflammatory pathways during infection within human macrophages and dendritic cells“.Mestrado em Microbiologia Aplicada. Faculdade de Ciências da Universidade de Lisboa
Supervisor of Joana Pereira Marques
Mestrado em Microbiologia Aplicada (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2012 - 2013 DECIPHERING HOST FACTORS FOR MYCOBACTERIA INTERNALIZATION DURING PHAGOCYTOSIS Mestrado em Microbiologia Aplicada. Faculdade de Ciências da Universidade de Lisboa.
Supervisor of Pedro Manuel Dias Timóteo
Mestrado em Microbiologia Aplicada (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2012 - 2013 Mycobacterium tuberculosis subversion of host vesicular traffic pathways Mestrado em Microbiologia Aplicada. Faculdade de Ciências da Universidade de Lisboa.
Supervisor of Joana Margarida Nunes Bugalhão
Mestrado em Microbiologia Aplicada (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2012 - 2013 O PAPEL DE PORINAS E DE BOMBAS DE EFLUXO DE MICOBACTÉRIAS NA IMUNIDADE INATA E RESISTÊNCIA AOS ANTIBIÓTICOS. Trabalho de investigação para tese desenvolvido em laboratório
Supervisor of Vera Alexandra Canária Fernandes
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2007/09/01 - 2012/12/09 Role of pro and anti-inflammatory lipids in intracellular survival and killing of mycobacteria. Orientação doutoramento PhD Supervision of the student Paulo Bettencourt.
Supervisor of Paulo Bettencourt
Doutoramento (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2012 - 2012 Células dendríticas na imunidade inata e adaptativa na Tuberculose
Supervisor of Vania Alice dos Santos Amaral
Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2009 - 2010 Desenvolvimento de um método para avaliar a sobrevivência/morte de Mycobacterium tuberculosis em macrófagos humanos por fluorimetria. Mestrado em Microbiologia Aplicada. Faculdade de Ciências da Universidade de Lisboa.
Supervisor of Marta Seixas Barroso
Mestrado em Microbiologia Aplicada (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2009 - 2010 Role of mycobacteria porins and efflux pumps on the intracellular survival within macrophages. Mestrado em Microbiologia Aplicada. Faculdade de Ciências da Universidade de Lisboa.
Supervisor of David Alexandre Pires
Mestrado em Microbiologia Aplicada (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2005/07/01 - 2009/11/23 Identification and manipulation of phagosomal membrane signaling networks to activate killing mechanisms of macrophages infected with mycobacteria. PhD Supervision of the student Bibhuti Bhusan Mishra
Supervisor of Bibhuti Bhusan Mishra
Doutoramento (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2008 - 2009 Estudo de pró-fármacos derivados da pirazinamida e da sua combinação com anti-inflamatórios não esteróides para o tratamento de micobacterioses. Mestrado Microbiologia Clínica, FMUL
Supervisor of Marta Filipa Simões
Mestrado Microbiologia Clínica (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2004/09/01 - 2008/03/05 The links between membrane actin assembly by mycobacterial phagosomes, and phagosome maturation, macrophage activation and Pathogen killing . PhD Supervision of the student Maria Luisa Jordão
Supervisor of Maria Luísa Jordão
Doutoramento (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2003 - 2004 Estudo do potencial do uso de formas lipossomais de antibióticos beta-lactâmicos no tratamento de micobacterioses. Mestrado em Química Farmacêutica, FFUL
Supervisor of Maria Luisa Jordão
Mestrado em Química Farmacêutica (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2020/01/31 - 2020/01/31 II Simpósio de Investigação em Tuberculose e outras micobactérias não tuberculosas, em Portugal (2020/01/31 - 2020/01/31)
Symposium (Co-organisor)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/04/04 - 2018/04/04 Science Talks: Tuberculosis. 2018 (2018/04/04)
Meeting (Member of the Organising Committee)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2013/05/21 - 2013/05/21 “VI-Scienceshop: TUBERCULOSE: development of new strategies to treat TB” 2013 (2013/05/21 - 2013/05/21)
Workshop (Co-organisor)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2009/04/04 - 2009/04/04 URIA Workshop Mycobacterium Biology and Pathogenesis Faculdade de Farmácia, 2009 (2009/04/04 - 2009/04/04)
Workshop
Universidade de Lisboa Faculdade de Farmácia, Portugal
2006/07/02 - 2006/07/02 Second Workshop on “Host pathogen Interactions and Cell Signaling”. 2006 (2006/07/02 - 2006/07/02)
Workshop (President of the Organising Committee)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2003/05/21 - 2003/05/21 Workshop on Host-pathogen Interactions and cell signaling. 2003 (2003/05/21 - 2003/05/21)
Workshop (President of the Organising Committee)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2003/04/13 - 2003/04/16 Primeiro Congresso da Sociedade Portuguesa de Ciências Farmacêuticas (2003/04/13 - 2003/04/16)
Congress (Member of the Organising Committee)
Sociedade Portuguesa de Ciências Farmacêuticas, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2023/11/27 “Deciphering the roles of ribonuclease PNPase in the human pathogen Listeria monocytogenes: Regulation of biofilms, cell invasion and stress response”
(Thesis) Arguer
Ana Patrícia Páscoa Quendera (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2023/05/19 “Unveiling the non-coding transcriptome and the role of ProQ on Burkholderia cenocepacia virulence
(Thesis) Main arguer
Tiago André Melicias Pita (PhD)
Instituto Superior Técnico, Universidade de Lisboa, Portugal
2022/12 CteG, a Chlamydia trachomatis protein involved in host cell lytic exit
(Thesis) Arguer
Inês Isabel Serrano Pereira (PhD)
Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa, Portugal
2016/04 Particulate delivery system for mucosal immunisation with Mycobacterium bovis bacille Calmette Guerin.
(Thesis) Arguer
Liliana Aranha Caetano (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015/01/08 Manipulation of host cell functions by Salmonella: the role of the bacterial effector protein SteA.
(Thesis) Main arguer
Lia Dora David Domingues (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2013/03/01 Candida dubliniensis versus Candida albicans adhesion and biofilm formation.
(Thesis) Main arguer
Mariana Contente Rangel Henriques (PhD)
Universidade do Minho, Portugal
2013 Novas vias para o controlo do crescimento do Mycobacterium avium.
(Thesis) Main arguer
Sofia Isabel Lapa Ribeiro de Sousa Fernandes (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012/11/18 Roles played by Hfq-like RNA chaperones and sRNAs on the virulence of Burkholderia cepacia complex bacteria.
(Thesis) Main arguer
Christian Gomes da Silva Ramos (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012/09/10 Roles de l'ATP et de ses metabolites au cours de la tuberculose.
(Thesis) Main arguer
Nicolas Dubois (PhD)
Institut Pasteur de Paris, Université Paris Diderot (Paris 7), France
2012/06/07 ”Apoptosis: how it restricts Legionella pneumophila intracellular replication and how it can be neutralized by a type IV effector protein”.
(Thesis) Main arguer
Catarina Sofia Viana Nogueira (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2008 The antimycobacterial activity of thioridazine derivatives against drug resistant Mycobacterium tuberculosis: In vitro, ex vivo and in vivo studies.
(Thesis) Main arguer
Marta Sofia Martins (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2021/02 - Current Nature Communications Nature
2020/01/02 - Current Frontiers in Immunology Frontiers
2019/03/01 - Current Innate Immunity (1753-4267)
2019/02/01 - Current Scientific reports (2045-2322) Nature
2018/02/01 - Current Cellular Microbiology Wiley
2017/02/01 - Current Frontiers in Microbiology Frontiers
2017/02/01 - Current International journal of molecular sciences (1422-0067)
2017/02/01 - Current Nutrients (2072-6643)
2017/02/01 - Current Tuberculosis research and treatment (2090-1518)
2017 - Current Frontiers in cellular and infection microbiology Frontiers
2016/02/01 - Current Molecular immunology (1872-9142)
2016/02/01 - Current Molecules ( 1420-3049)
2015/02/01 - Current Oncotarget (1949-2553)
2014/02/01 - Current European Journal of Cell Biology (1618-1298)
2008/02/01 - Current Microbial Biotechnology (1751-7907)

Conference scientific committee

Conference name Conference host
2020 - 2020 II Simpósio de Investigação em Tuberculose e outras micobactérias não tuberculosas, em Portugal
2019/06/24 - 2019/06/27 12th iMed.UL Postgraduate Students Meeting
2018/07/02 - 2018/07/05 11th iMed.UL Postgraduate Students Meeting
2017/09/01 - 2017/11/01 Microbiotec'17
2017/07/23 - 2017/07/25 10th iMed.UL Postgraduate Students Meeting
2016/07/23 - 2016/07/25 9th iMed.UL Postgraduate Students Meeting
2015/09/25 - 2015/12/01 Microbiotec'15
2015/07/23 - 2015/07/25 8th iMed.UL Postgraduate Students Meeting
2013/12/03 - 2013/12/08 Microbiotec'13 Aveiro
2006 - 2006 Second Workshop on ¿Host pathogen Interactions and Cell Signaling¿. 2006
2003 - 2003 Primeiro Congresso da Sociedade Portuguesa de Ciências Farmacêuticas
2003 - 2003 Workshop on Host-pathogen Interactions and cell signaling. 2003

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021/02/17 - Current Microbiologia e Saúde: Módulo Microbiologia Humana. Mestrado Microbiologia Aplicada Faculdade de Ciências da U-Lisboa. Coordenador Mestrado Microbiologia Aplicada (Mestrado) Universidade de Lisboa Faculdade de Ciências, Portugal
2010/10/06 - Current Cellular Microbiology. Mestrado Ciência Biofarmacêuticas. Faculdade de Farmácia, U-Lisboa. Coordenador. Mestrado Ciências Biofarmacêuticas (Master) Universidade de Lisboa Faculdade de Farmácia, Portugal
2010/09/15 - 2031/02/04 Imunologia. Mestrado Integrado em Ciências Farmacêuticas. Coordenador desde 2021. Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/03/01 - 2024/03/01 Placenta immunity: roles during pregnancy and during congenital infections Infeções congénitas Modulo 1 da Terceira Reunião SPFCS sobre Infeciologia. (Pós-Graduação) Sociedade Portuguesa de Farmacêuticos em Cuidados de Saúde, Portugal
2023/04/17 - 2023/04/21 UC de Host Responses to Microbial Infection do curso de doutoramento "PhD Program in Molecular Biosciences - Profile in Molecular Microbiology and Infection Biology”. ITQB, Instituto de tecnologia Química Biológica Abel Xavier PhD Program in Molecular Biosciences (Doutoramento) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2023/03/03 - 2023/03/03 Patogénese na infeção por Mycobacterium tuberculosis Integrado no Modulo 1 Principais bactérias associadas a infeções do trato respiratório da Segunda Reunião SPFCS sobre Infeciologia. Segunda Reunião SPFCS sobre Infeciologia. (Pós-Graduação) Sociedade Portuguesa de Farmacêuticos em Cuidados de Saúde, Portugal
2023/03/03 - 2023/03/03 Vacinas antituberculose Integrado no Modulo 3 Prevenção e tratamento da Segunda Reunião SPFCS sobre Infeciologia Segunda Reunião SPFCS sobre Infeciologia. (Pós-Graduação) Sociedade Portuguesa de Farmacêuticos em Cuidados de Saúde, Portugal
2022/03/11 - 2022/03/12 Primeira Reunião SPFCS sobre Infecciologia Infeção por HIV . As novidades da outra pandemia. Março de 2022 (Pós-Graduação) Sociedade Portuguesa de Farmacêuticos em Cuidados de Saúde, Portugal
2020/09/30 - 2020/12/30 III Curso Pós graduado de actualização em Virologia/Curso SARS-Cov2 e Covid-19 (Pós-Graduação) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/02/17 - 2020/06/30 Microbiologia e Saúde. Mestrado Microbiologia Aplicada Faculdade de Ciências da U-Lisboa. Coordenador. Mestrado em Microbiologia Aplicada (Mestrado) Universidade de Lisboa Faculdade de Ciências, Portugal
2010/04/01 - 2020/04/01 Laboratório de Microbiologia II. Mestrado Microbiologia Aplicada. FC-U.Lisboa Mestrado Microbiologia Aplicada (Mestrado) Universidade de Lisboa Faculdade de Ciências, Portugal
2008/09/20 - 2020/02/11 Biologia Celular. Mestrado Integrado Ciências Farmacêuticas. Coordenador. Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/02/07 - 2020/02/07 Coinfeção HIV/Mycobacterium tuberculosis. II Curso Pós-Graduado de Atualização em Virologia: Coinfeções e Comorbilidades Associadas à Infeção por HIV (Especialização pós-licenciatura) Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/02/07 - 2020/02/07 O processo inflamatório associado à infeção por HIV. II Curso Pós-Graduado de Atualização em Virologia: Coinfeções e Comorbilidades Associadas à Infeção por HIV (Especialização pós-licenciatura) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/03/18 - 2019/03/22 Exploring innate immunity for host directed therapies for Tuberculosis. PhD course, Universidade de Coimbra: Fighting infection PDBEB (2018-19 edition) Biologia Experimental e biomedicina BEB (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal
1988/09/25 - 2007/07/31 Biologia Celular. Licenciatura em Ciência Farmacêuticas. Faculdade Farmácia da Universidade de Lisboa. Coordenador 2004-2006. Licenciatura em Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2005/11/18 - 2005/11/30 Functional Microscopy of Host-Pathogen interactions. Join EMBO University of Cape Town-SA course Practical Course (Postgraduate Certificate) University of Cape Town, South Africa

European Molecular Biology Laboratory, Germany
2004/02/09 - 2004/02/13 Microscopia fluorescente e técnicas de marcação. Curso pós graduado FFUL. Coordenador/organizador. Pós graduação (Postgraduate Certificate) Universidade de Lisboa Faculdade de Farmácia, Portugal
2004/02/02 - 2004/02/06 Cultura Celular. Curso pós graduado FFUL. Coordenador/organizador Formação Pós graduada (Postgraduate Certificate) Universidade de Lisboa Faculdade de Farmácia, Portugal
2000/09/01 - 2000/09/30 Pré doc Course 2000. Griffiths laboratory. European Molecular Biology Laboratory, EMBL-Heidelberg. Pre-doc 2000 (Doktor (PhD)) European Molecular Biology Laboratory, Germany
1990/07/01 - 1990/07/31 Curso avançado em genética bacteriana 1990. Curso pós graduado FFUL. (Pós-Graduação) Universidade de Lisboa Faculdade de Farmácia, Portugal

Evaluation committee

Activity description
Role
Institution / Organization Funding entity
2022/10/03 - 2022/10/28 European Commission, European Research Executive Agency, HADEA Horizon HLTH-2022 Europe-diseases-06-02, expert
Evaluator
European Commission, Research European Agency, Belgium European Commission, Health and digital Executive agency (HaDEA)
2020/05/20 - 2020/06/08 Avaliador de projetos FCT 2ª edição do apoio “RESEARCH 4 COVID-19 Fundação para a Ciência e a Tecnologia, Portugal
2019 - 2019 Comissão científica iMed.UL Postgraduate Students Meeting 2019
2018 - 2018 Comissão científica iMed.UL Postgraduate Students Meeting 2018
2017/09/04 - 2017/12/12 Comissão Científica Microbiotec'17
Evaluator
Sociedade Portuguesa de Microbiologia, Portugal
2017 - 2017 Comissão científica iMed.UL Postgraduate Students Meeting 2017
2016 - 2016 Comissão científica iMed.UL Postgraduate Students Meeting 2016
2015/09/05 - 2015/12/13 Comissão Científica Microbiotec'15 Sociedade Portuguesa de Bioquímica, Portugal
2015 - 2015 Comissão científica iMed.UL Postgraduate Students Meeting 2015
2013/12/03 - 2013/12/08 Comissão Científica Microbiotec'13 Sociedade Portuguesa de Microbiologia, Portugal

Other jury / evaluation

Activity description Institution / Organization
2023/06 - 2023/06 Evaluation of grants submitted to UKRI, UK Research and Innovation, Medical research council, London. Reference: MR/Y013158/1 Medical Research Council, United Kingdom
2022/10/03 - 2022/10/28 European Commission, European Research Executive Agency, HADEA Horizon HLTH-2022 Europe-diseases-06-02, Expert: evaluation European Commission, Research European Agency, Belgium
2022/03/18 - 2022/04/18 Grant evaluation Biotechnology and Biological Sciences Research Council UKRI (UK research and innovation) 2022 (Ref 073065437); BBSRC Reference: BB/X000613/1 Biotechnology and Biological Sciences Research Council, United Kingdom
2022/03/01 - 2022/04/01 Grant evaluation India Alliance DBT Welcome IA/I/22/1/506236 Wellcome Trust DBT India Alliance, India
2021/11/01 - 2021/12/01 Projetos Medical Research Council UK. Ref 195015953; Grant Reference: MR/W025760/1 UK Research and Innovation, United Kingdom

Medical Research Council, United Kingdom
2020/05/20 - 2020/06/08 Avaliador de projetos FCT 2ª edição do apoio ¿RESEARCH 4 COVID-19 Fundação para a Ciência e a Tecnologia, Portugal
2019 - 2019 Wellcome Trust International Training Fellowship 216662/Z/19/Z Applicant name Dr Elouise Kroon Wellcome Trust, United Kingdom
2017/08/05 - 2017/08/30 National Research Foundation, NRF, South Africa. Thuthuka. A. Nienaber project National Research Foundation, South Africa
2017/04/01 - 2017/04/30 Agence Nationale de Recherche ANR, Fr, 2017-CE15, project MtbRup Agence nationale de la recherche, France
2016/08/01 - 2016/08/16 National Research Foundation, NRF, South Africa. Thuthuka. 2016 project BR Abrahams National Research Foundation, South Africa
Distinctions

Award

2018 Janssen Innovation Prize for Infectious Diseases
2016 Janssen Innovation Prize for Infectious Diseases
2013 Immunotools2013
2011 Award to participate on Keystone TB meeting "Tuberculosis: Immunology, Cell Biology and Novel Vaccination Strategies (J3)",
2007 Scholarship Award for participating in the Keystone TB meeting from Lab. research to field trials (C6-2007)
2006 Prémio Cotec (Associação Empresarial para a Inovação)/Fundação Luso Americana 2006 iniciativa CoHite
2006 Prémio Câmara Pestana
2005 EMBO fellowship
Gesellschaft zur Förderung der Lebenswissenschaften Heidelberg GmbH, Germany
2001 Bolsa Gulbenkian de Cientista convidado
Fundação Calouste Gulbenkian, Portugal
2000 EMBO fellowship
Gesellschaft zur Förderung der Lebenswissenschaften Heidelberg GmbH, Germany

Other distinction

2019 Mulheres na Ciência (Women in Science)
Ciência Viva, Portugal