Personal identification

Full name
Maria Clara Ferreira de Almeida Cardia Gomes

Citation names

  • Gomes, Maria
  • Gomes, M. C.
  • Maria C. Gomes

Author identifiers

Ciência ID


Knowledge fields

  • Exact Sciences - Chemical Sciences - Polymer Science
  • Natural sciences - Biological Sciences - Cell Biology
  • Engineering and Technology - Nano-technology - Nano-materials
  • Exact Sciences - Chemical Sciences - Organic Chemistry
  • Natural sciences - Biological Sciences - Microbiology
  • Exact Sciences - Chemical Sciences - Inorganic Chemistry
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
  • Medical and Health Sciences - Medical Biotechnology - Biomaterials


Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Proficiency (C2) Advanced (C1)
Degree Classification
2013 - 2017/06/17
Nanosciences and Nanotechnology (Doutoramento)
Major in Sem especialidade
Universidade de Aveiro, Portugal
"Photoactive nanoparticles for optical bioimaging" (THESIS/DISSERTATION)
2016/01 - 2016/07
Advanced Confocal Raman Microscopy couse (Outros)
University Health Network, Canada
2016/06 - 2016/06
Advanced Course in TEM for cell imaging (Outros)
University Health Network, Canada
2016/05 - 2016/05
ARC Mouse handling wet lab (Outros)
University Health Network, Canada
2016/05 - 2016/05
ARC Anesthesia Wet Lab (Outros)
University Health Network, Canada
2014 - 2014
Advanced Course in Photobiological Sciences (Curso médio)
Major in Photobiology
European Society of Photobiology, Italy
2009 - 2010
Biology (Mestrado)
Major in Clinical and Ambiental Microbiology
Universidade de Aveiro Departamento de Biologia, Portugal
"Cationic galactoporphyrins on microoganisms photoinactivation" (THESIS/DISSERTATION)
2004 - 2009
Biology (Licenciatura)
Universidade de Aveiro, Portugal


Host institution
2019/12/15 - Current Contracted Researcher (Research) Universidade de Aveiro CICECO, Portugal
Universidade de Aveiro CICECO, Portugal
2019/06/01 - 2019/12/14 Postdoc (Research) Universidade de Aveiro CICECO, Portugal
2017/10/04 - 2019 Postdoc (Research) Universidade de Aveiro CICECO, Portugal
2016/01 - 2016/07 Research Trainee (Research) University Health Network, Canada
University Health Network, Canada


Designation Funders
2018/07 - 2022/06 Hidrogéis de Lisados de Plaquetas para Regeneração do Miocárdio
Provided by PTCRIS: PTDC/BTM-MAT/30869/2017
Fundação para a Ciência e a Tecnologia
Provided by PTCRIS: SFRH/BD/88334/2012
Fundação para a Ciência e a Tecnologia


Designation Funders
2023/05/01 - Current PRISM-LT - PRInted Symbiotic Materials as a dynamic platform for Living Tissues production
Universidade de Aveiro, Portugal
European Innovation Council
2021/03/28 - 2024/03/27 Bioinspired tile-matching to create ultrastructured bone microtissues in a close-to-native fashion
Universidade de Aveiro, Portugal

Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
2018/07/22 - 2022/06/21 Platelet Lysate Hydrogels for Myocardial Repair
Co-Principal Investigator (Co-PI)
Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
2018/07 - 2020/02/01 PANGEIA- Microencapsulated 3D+ Cancer-Stroma Microtumor-based In vitro Testing Platforms for High-Throughput Screening of Combinatorial Therapies for Pancreatic Cancer
Fundação para a Ciência e a Tecnologia
Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia


Book chapter
  1. Custódio, C. A.; Santos, S. C.; Monteiro, C. F.; Deus, I. A.; Maria C. Gomes; Mano, J. F.. "Chapter 26. Animal Protein-based Soft Materials for Tissue Engineering Applications". In Soft Matter for Biomedical Applications, edited by João F. Mano; Helena S. Azevedo; João Borges, 660-683. Royal Society of Chemistry, 2021.
    Published • 10.1039/9781839161124-00660
  2. Deus, Inês A.; Santos, Sara C.; Monteiro, Cátia F.; Gomes, M. C. ; Custódio, Catarina A.; Mano, Joao F.. "Human protein-based soft materials for tissue engineering applications". In Soft Matter for Biomedical Applications. 2021.
Conference poster
  1. Ana Rita Pinho; Dora Gosta; Maria C. Gomes; João F. Mano. "Protein-based liquified systems: a step closer to personalized medicine". Paper presented in 4th International Conference on Biological and Biomimetic Adhesives, 2021.
  2. Gomes, Maria. "Carbohydrate Coated Gold Nanoparticles as SERS probes for Confocal Raman Microscopy of Cancer Cells". 2016.
  3. Gomes, Maria. "Photodynamic Inactivation of Conidia of Penicillium chrysogenum by Cationic Porphyrins". Paper presented in 14th Congress of the European Society for Photobiology (ESP), Geneva (Switzerland), 2011.
  4. Gomes, Maria. "Glycosylated Porphyrinoids for PDT applications". Paper presented in International Symposion on Advances in Synhtesis and Medicinal Chemistry, 2011.
  5. Maria C. Gomes. "Cationic galactoporphyrins for the photoinactivation of microorganisms". 2011.
  6. Gomes, Maria. "Porphyrins and phthalocyanines for wastewater treatment". Paper presented in European Symposium on Organic Chemistry, 2011.
  7. Gomes, Maria. "Synthesis, Caracterization and Biological Studies of Cationic Galactoporphyrins". Paper presented in International Conference on Porphyrins and Phthalocyanines, 2010.
  8. Gomes, Maria. "New cationic glycoporphyrins for the photoinactivation of microorganisms". Paper presented in Portuguese Young Chemists Meeting, 2010.
Journal article
  1. Pinho, Ana R.; Gomes, Maria C.; Costa, Dora C. S.; Mano, João F.. "Bioactive Self-Regulated Liquified Microcompartments to Bioengineer Bone-Like Microtissues". Small (2023): http://dx.doi.org/10.1002/smll.202305029.
  2. Zargarzadeh, Mehrzad; Gomes, Maria C.; Patrício, Sónia G.; Custódio, Catarina A.; Mano, João F.. "A Self-Sustaining Hydrogels with Autonomous Supply of Nutrients and Bioactive Domains for 3D Cell Culture". Advanced Functional Materials (2023): http://dx.doi.org/10.1002/adfm.202214372.
  3. Gomes, Maria C.; Pinho, Ana Rita; Custódio, Catarina; Mano, João F.. "Self-Assembly of Platelet Lysates Proteins into Microparticles by Unnatural Disulfide Bonds for Bottom-up Tissue Engineering". Advanced Materials (2023): http://dx.doi.org/10.1002/adma.202304659.
  4. Oliveira, Cláudia S.; Nadine, Sara; Gomes, Maria C.; Correia, Clara R.; Mano, João F.. "Bioengineering the human bone marrow microenvironment in liquefied compartments: A promising approach for the recapitulation of osteovascular niches". Acta Biomaterialia 149 (2022): 167-178. http://dx.doi.org/10.1016/j.actbio.2022.07.001.
  5. Ladeira, Bruno Miguel; Maria C. Gomes; Custodio, Catarina; Mano, João Filipe Colardelle da Luz. Corresponding author: Custodio, Catarina. "High-Throughput Production of Microsponges from Platelet Lysate for Tissue Engineering Applications". Tissue Engineering Part C: Methods (2022): http://dx.doi.org/10.1089/ten.tec.2022.0029.
    Published • 10.1089/ten.tec.2022.0029
  6. Costa, Dora C. S.; Costa, Patrícia D. C.; Maria C. Gomes; Chandrakar, Amit; Wieringa, Paul A.; Moroni, Lorenzo; Mano, João F.. "Universal Strategy for Designing Shape Memory Hydrogels". ACS Materials Letters 4 (2022): 701-706. http://dx.doi.org/10.1021/acsmaterialslett.2c00107.
    Published • 10.1021/acsmaterialslett.2c00107
  7. Ng, Philipp; Pinho, Ana Rita; Maria C. Gomes; Demidov, Yan; Krakor, Eva; Grume, Daniela; Herb, Marc; et al. "Fabrication of Antibacterial, Osteo-inductor 3D Printed Aerogel-based Scaffolds by Incorporation of Drug Laden Hollow Mesoporous Silica Microparticles into the Self-assembled Silk Fibroin Biopolymer". Macromolecular Bioscience (2022): 2100442. http://dx.doi.org/10.1002/mabi.202100442.
    Published • 10.1002/mabi.202100442
  8. Jesus, Diana; Pinho, Ana R.; Maria C. Gomes; Oliveira, Cláudia S.; Mano, João F.. "Emerging modulators for osteogenic differentiation: a combination of chemical and topographical cues for bone microenvironment engineering". Soft Matter 18 16 (2022): 3107-3119. http://dx.doi.org/10.1039/d2sm00009a.
    Published • 10.1039/d2sm00009a
  9. Maria C. Gomes; Chen, Juan; Cunha, Angela; Trindade, Tito; Zheng, Gang; Tomé, João P. C.. "Complex cellular environments imaged by SERS nanoprobes using sugars as an all-in-one vector". Journal of Materials Chemistry B (2021): http://dx.doi.org/10.1039/d1tb01360b.
    Published • 10.1039/d1tb01360b
  10. Maria C. Gomes; Costa, Dora C. S.; Oliveira, Cláudia S.; Mano, João F.. Corresponding author: Maria C. Gomes. "Design of Protein-Based Liquefied Cell-Laden Capsules with Bioinspired Adhesion for Tissue Engineering". Advanced Healthcare Materials (2021): 2100782. http://dx.doi.org/10.1002/adhm.202100782.
    Published • 10.1002/adhm.202100782
  11. Bharmoria, Pankaj; Bisht, Meena; Maria C. Gomes; Martins, Margarida; Neves, Márcia C.; Mano, João F.; Bdikin, Igor; Coutinho, João A. P.; Ventura, Sónia P. M.. "Protein-olive oil-in-water nanoemulsions as encapsulation materials for curcumin acting as anticancer agent towards MDA-MB-231 cells". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-88482-3.
    Published • 10.1038/s41598-021-88482-3
  12. Gomes, Maria C.; Mano, João F.. Corresponding author: Gomes, Maria C.. "Chemical modification strategies to prepare advanced protein-based biomaterials". Biomaterials and Biosystems 1 (2021): 100010. http://dx.doi.org/10.1016/j.bbiosy.2021.100010.
    Published • 10.1016/j.bbiosy.2021.100010
  13. Neto, Mafalda D.; Stoppa, Aukha; Neto, Miguel A.; Oliveira, Filipe J.; Gomes, Maria C.; Boccaccini, Aldo R.; Levkin, Pavel A.; Oliveira, Mariana B.; Mano, João F.. "Fabrication of Quasi-2D Shape-Tailored Microparticles using Wettability Contrast-Based Platforms". Advanced Materials 33 14 (2021): 2007695. http://dx.doi.org/10.1002/adma.202007695.
  14. Bharmoria, Pankaj; Mondal, Dibyendu; Pereira, Matheus M.; Neves, Márcia C.; Almeida, Mafalda R.; Maria C. Gomes; Mano, João F.; et al. "Instantaneous fibrillation of egg white proteome with ionic liquid and macromolecular crowding". Communications Materials 1 1 (2020): http://dx.doi.org/10.1038/s43246-020-0035-0.
    Published • 10.1038/s43246-020-0035-0
  15. Lourenço, Leandro M. O.; Rocha, Deisy M. G. C.; Ramos, Catarina I. V.; Maria C. Gomes; Almeida, Adelaide; Faustino, Maria A. F.; Almeida Paz, Filipe A.; et al. "Photoinactivation of Planktonic and Biofilm Forms of Escherichia coli through the Action of Cationic Zinc(II) Phthalocyanines". ChemPhotoChem 3 5 (2019): 251-260. http://dx.doi.org/10.1002/cptc.201900020.
    Published • 10.1002/cptc.201900020
  16. Simões, C.; Maria C. Gomes; Neves, M.G.P.M.S.; Cunha, Â.; Tomé, J.P.C.; Tomé, A.C.; Cavaleiro, J.A.S.; Almeida, A.; Faustino, M.A.F.. "Photodynamic inactivation of Escherichia coli with cationic meso-tetraarylporphyrins - The charge number and charge distribution effects". Catalysis Today 266 (2016): 197-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-84969753160&partnerID=MN8TOARS.
    Published • 10.1016/j.cattod.2015.07.031
  17. Maria C. Gomes; Cunha, Â.; Trindade, T.; Tomé, J.P.C.. "The role of surface functionalization of silica nanoparticles for bioimaging". Journal of Innovative Optical Health Sciences 9 4 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84976477957&partnerID=MN8TOARS.
    Published • 10.1142/S1793545816300056
  18. Lourenço, L.M.O.; Sousa, A.; Maria C. Gomes; Faustino, M.A.F.; Almeida, A.; Silva, A.M.S.; Neves, M.G.P.M.S.; et al. "Inverted methoxypyridinium phthalocyanines for PDI of pathogenic bacteria". Photochemical and Photobiological Sciences 14 10 (2015): 1853-1863. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942929561&partnerID=MN8TOARS.
    Published • 10.1039/c5pp00145e
  19. Rocha, D.M.G.C.; Venkatramaiah, N.; Maria C. Gomes; Almeida, A.; Faustino, M.A.F.; Almeida Paz, F.A.; Cunha, A.; Tomé, J.P.C.. "Photodynamic inactivation of Escherichia coli with cationic ammonium Zn(II) phthalocyanines". Photochemical and Photobiological Sciences 14 10 (2015): 1872-1879. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942855338&partnerID=MN8TOARS.
    Published • 10.1039/c5pp00147a
  20. Lopes, D.; Melo, T.; Santos, N.; Rosa, L.; Alves, E.; Maria C. Gomes; Cunha, Â.; et al. "Evaluation of the interplay among the charge of porphyrinic photosensitizers, lipid oxidation and photoinactivation efficiency in Escherichia coli". Journal of Photochemistry and Photobiology B: Biology 141 1 (2014): 145-153. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925440218&partnerID=MN8TOARS.
    Published • 10.1016/j.jphotobiol.2014.08.024
  21. Maria C. Gomes; Fernandes, R.; Cunha, Â.; Tomé, J.P.; Trindade, T.. "Fluorescence biolabeling using methylated silica nanoparticles containing a lanthanide complex". Journal of Materials Chemistry B 1 40 (2013): 5429-5435. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884607986&partnerID=MN8TOARS.
    Published • 10.1039/c3tb20688b
  22. Maria C. Gomes; Silva, Sandrina; Faustino, Maria A. F.; Neves, Maria G. P. M. S.; Almeida, Adelaide; Cavaleiro, José A. S.; Tomé, João P. C.; Cunha, Ângela. "Cationic galactoporphyrin photosensitisers against UV-B resistant bacteria: oxidation of lipids and proteins by1O2". Photochem. Photobiol. Sci. 12 2 (2013): 262-271. http://dx.doi.org/10.1039/c2pp25149c.
    Published • 10.1039/c2pp25149c
  23. Costa, Dora C. S.; Maria C. Gomes; Faustino, Maria A. F.; Neves, Maria G. P. M. S.; Cunha, Ângela; Cavaleiro, José A. S.; Almeida, Adelaide; Tomé, João P. C.. "Comparative photodynamic inactivation of antibiotic resistant bacteria by first and second generation cationic photosensitizers". Photochemical & Photobiological Sciences 11 12 (2012): 1905. http://dx.doi.org/10.1039/c2pp25113b.
    Published • 10.1039/c2pp25113b
  24. Maria C. Gomes; Woranovicz-Barreira, S.M.; Faustino, M.A.F.; Fernandes, R.; Neves, M.G.P.M.S.; Tomé, A.C.; Gomes, N.C.M.; et al. "Photodynamic inactivation of Penicillium chrysogenum conidia by cationic porphyrins". Photochemical and Photobiological Sciences 10 11 (2011): 1735-1743. http://www.scopus.com/inward/record.url?eid=2-s2.0-80455176460&partnerID=MN8TOARS.
Thesis / Dissertation
  1. Gomes, Maria. "Photoactive nanoparticles for oprical bio imaging". PhD, 2016.
  2. Gomes, Maria. "Cationic galactoporphyrins on microorganisms photoinactivation". Master, 2010.

Intellectual property

  1. Mano, Joao F.; Maria C. Gomes; Custódio, Catarina A.. 2022. "Platelet lysate-based microparticles, methods and uses thereof". Portugal.

Oral presentation

Presentation title Event name
Host (Event location)
2024/05/29 Cysteine mastery: transforming platelet lystate proteins into advanced microparticles World Biomaterials Congress (WBC) 2024
(Daegu, South Korea)
2010/11/10 Cationic galactopotphyrins on microorganims photoinactivation XVI Encontro Luso-Galego de Químic
(Aveiro, Portugal)


Thesis Title
Degree Subject (Type)
Institution / Organization
2023/09/16 - Current Assembly of capsules using a robotic arm to build macro-sized tissues
Universidade de Aveiro, Portugal
2023/09/15 - Current 3D living puzzles: assembly of micro-capsules to build macro-sized tissues
Biotechnology (Master)
Universidade de Aveiro, Portugal
2021/01/01 - Current Bioinspired protein-based liquified microcapsules with adhesive properties for bone regenerative medicine
PhD in Biomedicine (PhD)
Universidade de Aveiro CICECO, Portugal
2023/01/10 - 2023/06/01 Supramolecular protein-based hydrogels as delivery systems
BSc in Chemistry (Degree)
2021/09/01 - 2022/12/05 Chemical modification of human-derived proteins to develop personalized cell culture platforms and bioinks.
2021/09/19 - 2022/11/18 Detection of biomarkers associated to cancer
Master in Chemistry (Master)
2020/11/01 - 2021/03 Biomimetic human-based hydrogels through tannin-protein interactions

Event organisation

Event name
Type of event (Role)
Institution / Organization
2017/10/12 - Current Techdays Aveiro (2017/10/12 - 2017/10/14)
Exhibition (Co-organisor)
2019/10/21 - 2019/10/25 Training School under COST Action ENBA entitle: Biomimetic adhesive polymers and hydrogels (2019/10/21 - 2019/10/25)
Other (Member of the Organising Committee)
2018/11 - 2018/11 Training School under COST Action ENBA entitle: Biomimetic adhesive polymers and hydrogels (2018/11 - 2018/11)
2017 - 2017 ISBMS Congress - International symposium on bioinspired macromolecular systems (2017/11/06 - 2017/11/08)
Symposium (Member of the Organising Committee)
Universidade de Aveiro, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2016/05/21 - 2016/05/26 Poster communication
ASP conference

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2024/02/14 - Current Bioorganic Chemistry (Licenciatura) Universidade de Aveiro, Portugal
2023/09 - 2024/01 Técnicas de Comunicações e Apresentações (Communication and Presentation Techniques) (Licenciatura) Universidade de Aveiro, Portugal
2022/09/10 - 2022/12/07 Advanced Biomaterials and Biomimetics (Mestrado) Universidade de Aveiro, Portugal
2018/01/06 - 2019/06/14 Engineering of Cells and Tissues (Mestrado) Universidade de Aveiro, Portugal

Evaluation committee

Activity description
Institution / Organization Funding entity
2022/12/01 - 2023/01/31 Member of external evaluation jury of Marie Curie ITN Networks for MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01)

Journal scientific committee

Journal title (ISSN) Publisher
2020 - Current Materials Today Bio (2590-0064) Elsevier
2020 - Current Langmuir ASC Publications

Other jury / evaluation

Activity description Institution / Organization
2022 - Current Member of external evaluation jury of Marie Curie ITN Networks.
2022 - Current Member of external evaluation jury of Marie Curie ITN Networks. Type of action: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01)
2021/01/27 - Current Member of the Jury of the M. Sc. curricular unit "Seminários" in Biochemistry, at University of Aveiro, of Graduate André Filipe Dias Lima - monography on "Platelet lysates-based hydrogels as 3D cell culture platforms for cardiac regeneration"
2019/07/19 - Current Member of the Jury of the PhD curricular unit "Projeto tese" in Biotechnology, at University of Aveiro, of Graduate Lucia Isabel Ferreira Santos - monography on "Magnetic-responsive platforms to control cell behaviour for tissue engineering applications".
2020/10/28 - 2020/10/28 Member of the Jury of the PhD. curricular unit "Projeto de Tese" in Nanosciences and nanotechnology, at University of Aveiro, of Graduate Edgar Angelo Castanheira - monography on "Bioactive hybrid water-resistant adhesives for regenerative medicine".