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Joana Bicker (JB) is an Invited Assistant Professor at the Faculty of Pharmacy of the University of Coimbra (FFUC), integrated researcher at Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT) and a European Certified Pharmacologist (EuCP). She was also PI of project EpiMod (2022.03133.PTDC). She concluded a MSc in Pharmaceutical Sciences (2011) and a PhD in Pharmacology and Pharmacotherapy (2018) at FFUC. JB was selected as researcher in project 4Epilepsy (2019-2022) and team member in project N2BD (2018-2021). She was/is also team member of three other research projects (Mitoboost, Tryp-to-Brain, and NasalStep). She has a Scopus h-index of 19 and 1294 citations with 55 published articles in international journals. In addition, she is co-inventor of two patents. She was Invited Guest Editor of a Special Issue in Pharmaceutics (MDPI) and has been a regular reviewer of publications from Nature, Elsevier, Frontiers, MDPI and others. She received a Research Initiation Grant and a FCT individual PhD Fellow, and 12 awards, among which is the Lusitan Pharmaceutical Society Award. In 2024, she was awarded a Sandander Scholarship grant for the Innovation in Teaching course by Harvard Business Education. She supervised 1 PhD student from the Federal University of São Paulo (Brazil) and is currently supervising 3 FCT-funded PhD students. Her research interests include the blood-brain barrier (BBB) and CNS disorders, namely the development of BBB repairing treatments and new pharmacological approaches. She has experience in vitro/in vivo pharmacokinetic (ADME) and pharmacodynamic assays applied to drug screening of molecules directed at epilepsy, depression and Alzheimer’s disease, as well as therapeutic drug monitoring (personalized medicine), intranasal administration, and development/validation of bioanalytical techniques. She also has certification as Investigator-Coordinator in Animal Sciences (EU Functions A+B+D) by FELASA. She has collaborations with the pharmaceutical and biotechnology industries (e.g., BIAL, TargTex SA) and health institutions (Coimbra Hospital and University Centre, CHUC.EPE). From an international perspective she has acquired international training and collaborates with research teams from the University of Barcelona (Spain), Federal University of São Paulo (Brazil) and University of Warwick (UK).
Identification

Personal identification

Full name
Joana Bicker de Melo Alves Aparício

Author identifiers

Ciência ID
1110-A1AB-626F
Affiliation

Science

Category
Host institution
Employer
2019/02 - 2022/02 Researcher (Research) University of Coimbra, Portugal
Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), Portugal
(...)
2009/04 - 2010/03 Research Trainee (Research) University of Coimbra - Centre for Neuroscience and Cell Biology (CNC), Portugal
University of Coimbra - Centre for Neuroscience and Cell Biology (CNC), Portugal

Teaching in Higher Education

Category
Host institution
Employer
2022/09/01 - Current Invited Assistant Professor (University Teacher) University of Coimbra - Faculty of Pharmacy, Portugal
University of Coimbra - Faculty of Pharmacy, Portugal
2018/09/01 - 2019/08/31 Invited Assistant Professor (University Teacher) University of Coimbra - Faculty of Pharmacy, Portugal
University of Coimbra - Faculty of Pharmacy, Portugal
2017/09/01 - 2018/08/31 Invited Assistant Professor (University Teacher) University of Coimbra - Faculty of Pharmacy, Portugal
University of Coimbra - Faculty of Pharmacy, Portugal

Others

Category
Host institution
Employer
2012/01/01 - 2018/01/30 PhD Student University of Coimbra - Faculty of Pharmacy, Portugal
University of Coimbra - Centre for Neuroscience and Cell Biology (CNC), Portugal
2015/09 - 2016/01 Teaching Adjunct University of Coimbra - Faculty of Pharmacy, Portugal
Laboratory of Pharmacology and Pharmaceutical Care - Faculty of Pharmacy of the University of Coimbra, Portugal
2014/09 - 2015/01 Teaching Adjunct University of Coimbra - Faculty of Pharmacy, Portugal
Laboratory of Pharmacology and Pharmaceutical Care - Faculty of Pharmacy of the University of Coimbra, Portugal
Projects

Contract

Designation Funders
2019/02 - 2022/02 4Epilepsy: Promoting the quality-of-life of epileptic patients through personalized medicine
POCI-01-0145-FEDER-030478
Researcher
University of Coimbra - Faculty of Pharmacy, Portugal

Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), Portugal

Centro Hospitalar e Universitário de Coimbra EPE, Portugal
Foundation for Science and Technology (FCT)
Concluded
2012/01/01 - 2018/01/30 Screening Strategy for Evaluation of Drug Transport across the Blood-Brain Barrier: Application to Catechol-O-methyltransferase Inhibitors, Dopamine ß-hydroxylase Inhibitors and Dibenz[b,f]azepine-5-carboxamide Derivatives
SFRH/BD/78256/2011
PhD Student Fellow
University of Coimbra - Faculty of Pharmacy, Portugal

University of Coimbra - Centre for Neuroscience and Cell Biology (CNC), Portugal
Foundation for Science and Techology (FCT)
Concluded

Other

Designation Funders
2025/03 - Current NasalSteP – Targeted nose-to-brain drug-device products with fast-acting antidepressant properties
15636
Researcher
2023/03 - 2025/03 EpiMod: Epigenetic modulation of blood-brain barrier integrity for the prevention of epileptogenesis
2022.03133.PTDC
Principal investigator
University of Coimbra - Faculty of Pharmacy, Portugal

Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), Portugal
Ongoing
2023/01/01 - 2024/11/30 Tryp-to-Brain: Prenatal tryptophan as a key player in gut-brain axis dysfunction: an autism spectrum disorder preclinical approach
2022.01066.PTDC
Researcher
Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), Portugal
Concluded
2022/07/01 - 2023/07/30 MitoBOOST v2.0
01/SAICT/2021
Researcher
Biocant Associação de Transferência de Tecnologia, Portugal
Concluded
2018 - 2021 N2BD: Development of a Novel Nose-to-Brain Multifunctional Nanoplatform for the Treatment of Depression and Prevention of Pharmacoresistance Development
CENTRO-01-0145-FEDER-030752- N2BD
Researcher
University of Coimbra - Faculty of Pharmacy, Portugal

Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), Portugal
Foundation for Science and Technology (FCT)
Concluded