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Identification

Personal identification

Full name
Richard Andrew Billington

Citation names

  • Billington, Richard

Author identifiers

Ciência ID
1016-BE13-AF3C
ORCID iD
0000-0001-7288-8916
Education
Degree Classification
2002
Concluded
Pharmacology (Doctor)
University of Cambridge Clare Hall, United Kingdom
1999
Concluded
Biochemistry (Bachelor)
University of Bristol Faculty of Life Sciences, United Kingdom
Affiliation

Science

Category
Host institution
Employer
2002 - 2003 Postdoc (Research) University of Cambridge Clare Hall, United Kingdom

Teaching in Higher Education

Category
Host institution
Employer
2017 - Current Associate Professor (University Teacher) University of Plymouth School of Biological and Marine Sciences, United Kingdom
2008 - 2017 Lecturer (University Teacher) University of Plymouth School of Biological and Marine Sciences, United Kingdom
2003 - 2008 Lecturer (University Teacher) Università degli Studi del Piemonte Orientale Amedeo Avogadro - Sede di Novara, Italy
Outputs

Publications

Journal article
  1. Alexandra C. North; Luke J. Sutton; Jason L. Brown; Trenton W. J. Garner; Richard A. Billington; John W. Wilkinson; Manuela Truebano; Robert Puschendorf. "Predicting the invasiveness of alpine newts in the UK". Biological Invasions (2025): https://doi.org/10.1007/s10530-025-03543-2.
    10.1007/s10530-025-03543-2
  2. Jana Vanessa Huml; Jonathan S. Ellis; Sarah Rustage; Mark J. F. Brown; Richard Billington; Mairi E. Knight. "The tragedy of the common? A comparative population genomic study of two bumblebee species". Insect Conservation and Diversity (2023): http://dx.doi.org/10.1111/icad.12626.
    10.1111/icad.12626
  3. María Botella-Cruz; Susana Pallarés; Josefa Velasco; A. John Moody; Richard Billington; Andrés Millán; David T. Bilton. "The colonisation of saline waters is associated with lowered immune responses in aquatic beetles". Freshwater Biology (2022): https://doi.org/10.1111/fwb.13993.
    10.1111/fwb.13993
  4. Cioffi R; Moody AJ; Millán A; Billington RA; Bilton DT. "Physiological niche and geographical range in European diving beetles (Coleoptera: Dytiscidae).". (2016): http://europepmc.org/abstract/med/27330169.
    10.1098/rsbl.2016.0130
  5. Al-Shabany AJ; Moody AJ; Foey AD; Billington RA. "Intracellular NAD+ levels are associated with LPS-induced TNF-a release in pro-inflammatory macrophages.". (2016): http://europepmc.org/abstract/med/26764408.
    10.1042/BSR20150247
  6. Almzaiel AJ; Billington R; Smerdon G; Moody AJ. "Hyperbaric oxygen enhances neutrophil apoptosis and their clearance by monocyte-derived macrophages.". (2015): http://europepmc.org/abstract/med/26194051.
    10.1139/bcb-2014-0157
  7. Al-Abady ZN; Durante B; Moody AJ; Billington RA. "Large changes in NAD levels associated with CD38 expression during HL-60 cell differentiation.". (2013): http://europepmc.org/abstract/med/24216102.
    10.1016/j.bbrc.2013.10.170
  8. Almzaiel AJ; Billington R; Smerdon G; Moody AJ. "Effects of hyperbaric oxygen treatment on antimicrobial function and apoptosis of differentiated HL-60 (neutrophil-like) cells.". (2013): http://europepmc.org/abstract/med/23770209.
    10.1016/j.lfs.2013.06.003
  9. Sumaiya Hawar; William Vevers; Sahar Karieb; Batool K. Ali; Richard Billington; Jane Beal. "Biotransformation of patulin to hydroascladiol by Lactobacillus plantarum". Food Control 34 2 (2013): 502-508. http://dx.doi.org/10.1016/j.foodcont.2013.05.023.
    10.1016/j.foodcont.2013.05.023
  10. Plattner H; Sehring IM; Mohamed IK; Miranda K; De Souza W; Billington R; Genazzani A; Ladenburger EM. "Calcium signaling in closely related protozoan groups (Alveolata): non-parasitic ciliates (Paramecium, Tetrahymena) vs. parasitic Apicomplexa (Plasmodium, Toxoplasma).". (2012): http://europepmc.org/abstract/med/22387010.
    10.1016/j.ceca.2012.01.006
  11. Conforti L; Wilbrey A; Morreale G; Janeckova L; Beirowski B; Adalbert R; Mazzola F; et al. "Wld S protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice.". (2009): http://europepmc.org/abstract/med/19237596.
    10.1083/jcb.200807175
  12. Gambara G; Billington RA; Debidda M; D'Alessio A; Palombi F; Ziparo E; Genazzani AA; Filippini A. "NAADP-induced Ca(2+ signaling in response to endothelin is via the receptor subtype B and requires the integrity of lipid rafts/caveolae.". (2008): http://europepmc.org/abstract/med/18288637.
    10.1002/jcp.21407
  13. Galli U; Ercolano E; Carraro L; Blasi Roman CR; Sorba G; Canonico PL; Genazzani AA; Tron GC; Billington RA. "Synthesis and biological evaluation of isosteric analogues of FK866, an inhibitor of NAD salvage.". (2008): http://europepmc.org/abstract/med/18247435.
    10.1002/cmdc.200700311
  14. Billington RA; Genazzani AA; Travelli C; Condorelli F. "NAD depletion by FK866 induces autophagy.". (2008): http://europepmc.org/abstract/med/18227641.
    10.4161/auto.5635
  15. Billington RA; Travelli C; Ercolano E; Galli U; Roman CB; Grolla AA; Canonico PL; Condorelli F; Genazzani AA. "Characterization of NAD uptake in mammalian cells.". (2008): http://europepmc.org/abstract/med/18180302.
    10.1074/jbc.M706204200
  16. Tron GC; Pirali T; Billington RA; Canonico PL; Sorba G; Genazzani AA. "Click chemistry reactions in medicinal chemistry: applications of the 1,3-dipolar cycloaddition between azides and alkynes.". (2008): http://europepmc.org/abstract/med/17763363.
    10.1002/med.20107
  17. Genazzani AA; Billington RA. "[Pharmacokinetic and pharmacodynamic features of palonosetron].". (2008): http://europepmc.org/abstract/med/18564620.
  18. Billington RA; Genazzani AA. "PPADS is a reversible competitive antagonist of the NAADP receptor.". (2007): http://europepmc.org/abstract/med/17084890.
    10.1016/j.ceca.2006.10.002
  19. Deaglio S; Vaisitti T; Billington R; Bergui L; Omede' P; Genazzani AA; Malavasi F. "CD38/CD19: a lipid raft-dependent signaling complex in human B cells.". (2007): http://europepmc.org/abstract/med/17327405.
    10.1182/blood-2006-12-061812
  20. Pirali T; Gatti S; Di Brisco R; Tacchi S; Zaninetti R; Brunelli E; Massarotti A; et al. "Estrogenic analogues synthesized by click chemistry.". (2007): http://europepmc.org/abstract/med/17278167.
    10.1002/cmdc.200600192
  21. Billington RA; Harper C; Bellomo EA; Publicover S; Barratt CL; Genazzani AA. "Characterization of cyclic adenine dinucleotide phosphate ribose levels in human spermatozoa.". (2006): http://europepmc.org/abstract/med/16904113.
    10.1016/j.fertnstert.2006.03.030
  22. Moccia F; Billington RA; Santella L. "Pharmacological characterization of NAADP-induced Ca2+ signals in starfish oocytes.". (2006): http://europepmc.org/abstract/med/16890912.
    10.1016/j.bbrc.2006.05.157
  23. Billington RA; Bellomo EA; Floriddia EM; Erriquez J; Distasi C; Genazzani AA. "A transport mechanism for NAADP in a rat basophilic cell line.". (2006): http://europepmc.org/abstract/med/16403787.
    10.1096/fj.05-5058fje
  24. Floriddia EM; Pace D; Genazzani AA; Canonico PL; Condorelli F; Billington RA. "Sphingosine releases Ca2+ from intracellular stores via the ryanodine receptor in sea urchin egg homogenates.". (2005): http://europepmc.org/abstract/med/16259943.
    10.1016/j.bbrc.2005.10.091
  25. Appendino G; Prosperini S; Valdivia C; Ballero M; Colombano G; Billington RA; Genazzani AA; Sterner O. "SERCA-inhibiting activity of C-19 terpenolides from Thapsia garganica and their possible biogenesis.". (2005): http://europepmc.org/abstract/med/16124763.
    10.1021/np050115m
  26. Billington RA; Tron GC; Reichenbach S; Sorba G; Genazzani AA. "Role of the nicotinic acid group in NAADP receptor selectivity.". (2005): http://europepmc.org/abstract/med/15541466.
    10.1016/j.ceca.2004.06.009
  27. Billington RA; Bak J; Martinez-Coscolla A; Debidda M; Genazzani AA. "Triazine dyes are agonists of the NAADP receptor.". (2004): http://europepmc.org/abstract/med/15265807.
    10.1038/sj.bjp.0705886
  28. Billington RA; Thuring JW; Conway SJ; Packman L; Holmes AB; Genazzani AA. "Production and characterization of reduced NAADP (nicotinic acid-adenine dinucleotide phosphate).". (2004): http://europepmc.org/abstract/med/14606955.
    10.1042/BJ20031284
  29. Billington RA; Ho A; Genazzani AA. "Nicotinic acid adenine dinucleotide phosphate (NAADP) is present at micromolar concentrations in sea urchin spermatozoa.". (2002): http://europepmc.org/abstract/med/12356884.
    10.1113/jphysiol.2002.030098
  30. Bak J; Billington RA; Genazzani AA. "Effect of luminal and extravesicular Ca2+ on NAADP binding and release properties.". (2002): http://europepmc.org/abstract/med/12127965.
    10.1016/S0006-291X(02)00761-1
  31. Genazzani AA; Billington RA. "NAADP: an atypical Ca2+-release messenger?". (2002): http://europepmc.org/abstract/med/11931990.
    10.1016/S0165-6147(00)01990-8
  32. Bak J; Billington RA; Timar G; Dutton AC; Genazzani AA. "NAADP receptors are present and functional in the heart.". (2001): http://europepmc.org/abstract/med/11448777.
    10.1016/S0960-9822(01)00269-X
  33. Billington RA; Genazzani AA. "Characterization of NAADP(+) binding in sea urchin eggs.". (2000): http://europepmc.org/abstract/med/11006092.
    10.1006/bbrc.2000.3444