???global.info.a_carregar???
Soraia Caetano, finished her BSc in Celular and Molecular Biology by Universidade Nova de Lisboa, Faculdade de Ciências e Tecnologia (FCT NOVA). The MSc in Biotechnology was awarded in 2011 by Universidade de Aveiro (UA), and Soraia completed her PhD in Biology in 2017/07/25 by Universidade Nova de Lisboa, Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA). Soraia published 7 articles in peer reviewed journals, two of which as first or co-first author, presented her work in five national and international scientific meetings, and has received two travel awards to attend international congresses. Soraia did her PhD in the Molecular Biology field, with emphasis in regulation of gene expression of yeast cellular response to stress conditions. Soraia has participated in national and international projects, which funded her research. During her PhD, a five months period was spend abroad, at Prof. Patrick Van Dijck Laboratory, KU Leuven, Belgium. Also, Soraia was a member of the COST Action CA15133 entitled ¿The Biogenesis of Iron-sulfur Proteins: from Cellular Biology to Molecular Aspects (FeSBionet)¿ being part of the Work Group 1 (¿Functional analysis of the cellular machineries for the maturation of Fe/S proteins and the link to human diseases¿). Soraia also developed pedagogic skills, being a tutor of several bachelor and master students during her PhD studies, and co-supervised a bachelor student in 2018. Due to her interest in the mechanisms underlying host-pathogen interaction, Soraia successfully applied for an international call for a Postdoc position at Prof. Maria Mota laboratory, Instituto de Medicina Molecular (iMM), Universidade de Lisboa, thus in June 2019 Soraia started to develop her Postdoctoral studies at Prof. Maria Mota lab regarding the project "Hepatic metabolism driving Plasmodium replication". Later last year, Soraia transitioned to Miguel Prudêncio's laboratory, Instituto de Medicina Molecular (iMM), Universidade de Lisboa, being now applying her knowledge and skills by being an integrating part of the projects "Plasmodium infection of 3D hepatic cell cultures" funded by Instituto de Biologia Experimental e Tecnológica and "Whole-organism vaccines against P. falciparum and P. vivax malaria with enhanced efficacy and scope" funded by "la Caixa" Foundation.
Read full resume ↓
Identification

Personal identification

Full name
Soraia Caetano

Author identifiers

Ciência ID
1011-E693-6840
ORCID iD
0000-0001-7427-5670

Email addresses

  • soraia.caetano@medicina.ulisboa.pt (Professional)

Websites

Languages

Language Speaking Reading Writing Listening Peer-review
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
English Advanced (C1) Advanced (C1) Advanced (C1) Proficiency (C2)
Portuguese (Mother tongue)
Education
Degree Classification
2017/07/25
Concluded
 Biologia (Doutoramento)
Major in Especialidade: Biologia Molecular
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
"Stress response mechanisms underlying metal detoxification in yeast: The cases of cobalt, cadmium and iron." (THESIS/DISSERTATION)
 Aprovada por unanimidade
2011/12/19
Concluded
 Biotecnologia (Mestrado integrado)
Major in Molecular Biotechnology
Universidade de Aveiro, Portugal
"O Yap1 no stress causado pelo excesso de cobalto em S. cerevisiae" (THESIS/DISSERTATION)
 17 valores
2009/09
Concluded
 Biologia Celular e Molecular (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Seminário sobre a Diversidade e Evolução das Bactérias Endossimbiontes em eucariontes (invertebrados): papel das metodologias moleculares" (THESIS/DISSERTATION)
 13
Affiliation

Science

Category
Host institution 		Employer
2019/06/03 - Current Postdoc (Research) Instituto de Medicina Molecular, Portugal
Instituto de Medicina Molecular, Portugal
Projects

Grant

Designation Funders
2019/06/03 - 2021/11/30 Plasmodium Exploitation of Liver-specific Methionine Metabolism
HR17-00264
Post-doc
Instituto de Medicina Molecular, Portugal
 laCaixa Foundation
Ongoing
2019/06/03 - 2021/11/30 Hepatic metabolism driving Plasmodium replication
LISBOA-01-0145-FEDER-030751
Post-doc
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/03/15 - 2019/01/31 IF 2015
IF/00124/2015
Research Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2017/03/01 - 2018/02/28 Rethinking antifungal azoles: New tricks for old drugs
CBQ/04612, (ICL3535)
Research Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/12/08 - 2016/12/12 Mapping iron accumulation in Yeast by X-ray imaging: evidence for an alternative mechanism of Fe storage/detoxification
LS-2561
PhD Student Fellow
ESRF, France
 ESRF
Concluded
2014/02 - 2015/05 Exploration of novel molecular mechanisms involved in iron homeostasis
Provided by PTCRIS: 135550
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
2012/01 - 2012/12 Control of iron homeostasis by the Yeast activator proteins (Yaps) in eukaryotic cells
PTDC/BIA-MIC/108747/2008
Research Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011/06 - 2011/12 Control of iron homeostasis by the Yeast activator proteins (Yaps) in eukaryotic cells
PTDC/BIA-MIC/108747/2008
Master Student Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference abstract
  1. Cordeiro, A. C.; Caetano, S.M.; Amaral, C.; Pimentel, C.; Rodrigues-Pousada, C.. "Dealing with copper toxicity: New insights into copper detoxification in yeast". Paper presented in 41st FEBS Congress, Molecular and Systems Biology for a Better Life, Ephesus/Kusadasi, 2016.
    Published
  2. Pimentel, C.; Santos, C.; Vicente, C.; Caetano, S.; Rodrigues-Pousada, C.. "On the track of novel mechanisms controlling iron storage in yeast". Paper presented in FEBS EMBO 2014 Conference, Paris, 2014.
    Published
  3. Caetano, S.M.; Amaral, C; Menezes, R.; Rodrigues-Pousada, C.; Pimentel, C.. "Yap1- mediated repression of the yeast low affinity iron transporter gene, FET4, confers cadmium tolerance". Paper presented in FEBS/EMBO Congress “Mechanisms in Biology”, Paris, 2014.
    Published
  4. Pimentel, C.; Caetano, S.; Menezes, R. A.; Figueira, I.; Santos, C. N.; Boavida, R. B.; Santos, M.; Rodrigues-Pousada, C.. "The role of the yeast transcription factor Yap1 in Cobalt detoxification". Paper presented in FEBS Congress Mechanisms in Biology, St Petersburg, 2013.
    Published
Conference poster
  1. Pimentel, C.; Rodrigues-Pousada, C.; Amaral, C.; da Silva, S.; Caetano, S.M.; Cordeiro, A. C.. "New Pathways Of Metal Detoxification in Yeast". Paper presented in TimB3 - Twin to Illuminate Metals in Biology and Biocatalysis through Biospectroscopy, 2018.
  2. Caetano, S.; Amaral, C.; Menezes, R.; Rodrigues-Pousada, C.; Pimentel, C.. "Yap1-mediated repression of the yeast low affinity iron transporter gene, FET4, confers cadmium tolerance.". Paper presented in XX Jornadas de Levedura – Professor Nicolau Van Uden, 2014.
  3. Caetano, S.; Amaral, C.; Menezes, R.; Rodrigues-Pousada, C.; Pimentel, C.. "Cadmium tolerance mediated by the yeast transcription factor Yap1 requires the repression of FET4, a low affinity iron transporter gene". Paper presented in EMBO conference – Gene Transcription in yeast: From regulatory networks to mechanisms, 2014.
  4. Caetano, S.; Pimentel, C.; Rodrigues, M. C.; Menezes, R. A.; Rodrigues-Pousada, C.. "New insights into cadmium detoxification". Paper presented in EMBO Young Scientists’ Forum, 2013.
Journal article
  1. Rodrigues-Pousada, C.; Devaux, F.; Caetano, S.M.; Pimentel, C.; da Silva, S.; Cordeiro, A.C.; Amaral, C.. "Yeast AP-1 like transcription factors (Yap) and stress response: A current overview". Microbial Cell 6 6 (2019): 267-285. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068446106&partnerID=MN8TOARS.
    10.15698/mic2019.06.679
  2. Gaspar-Cordeiro, A.; Caetano, S.M.; Amaral, C.; Rodrigues-Pousada, C.; Pimentel, C.. "Ace1 prevents intracellular copper accumulation by regulating Fet3 expression and thereby restricting Aft1 activity". FEBS Journal 285 10 (2018): 1861-1872. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045739412&partnerID=MN8TOARS.
    10.1111/febs.14450
  3. Caetano, S.M.; Menezes, R.; Amaral, C.; Rodrigues-Pousada, C.; Pimentel, C.. "Repression of the low affinity iron transporter gene FET4: A novel mechanism against cadmium toxicity orchestrated by Yap1 via Rox1". Journal of Biological Chemistry 290 30 (2015): 18584-18595. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937964542&partnerID=MN8TOARS.
    10.1074/jbc.M114.600742
  4. Mazzola, D.; Pimentel, C.; Caetano, S.; Amaral, C.; Menezes, R.; Santos, C.N.; Eleutherio, E.; Rodrigues-Pousada, C.. "Inhibition of Yap2 activity by MAPKAP kinase Rck1 affects yeast tolerance to cadmium". FEBS Letters 589 19 (2015): 2841-2849. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941413618&partnerID=MN8TOARS.
    10.1016/j.febslet.2015.07.049
  5. Pimentel, C.; Caetano, S.M.; Menezes, R.; Figueira, I.; Santos, C.N.; Ferreira, R.B.; Santos, M.A.S.; Rodrigues-Pousada, C.. "Yap1 mediates tolerance to cobalt toxicity in the yeast Saccharomyces cerevisiae". Biochimica et Biophysica Acta - General Subjects 1840 6 (2014): 1977-1986. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897453901&partnerID=MN8TOARS.
    10.1016/j.bbagen.2014.01.032
  6. Pimentel, C.; Vicente, C.; Menezes, R.A.; Caetano, S.; Carreto, L.; Rodrigues-Pousada, C.. "The role of the Yap5 transcription factor in remodeling gene expression in response to Fe bioavailability". PLoS ONE 7 5 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84861203729&partnerID=MN8TOARS.
    10.1371/journal.pone.0037434
Thesis / Dissertation
  1. Caetano, Soraia; Caetano, Soraia Marques. "Stress response mechanisms underlying metal detoxification in yeast: The cases of cobalt, cadmium and iron". PhD, Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, 2017.
  2. Caetano, Soraia Cristina Marques. "O Yap1 no stress causado pelo excesso de cobalto em S. cerevisiae". Master, Universidade de Aveiro, 2011. http://hdl.handle.net/10773/8214.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2016/11/23 Transcriptional and post-transcriptional mechanisms underlying cadmium detoxification in yeast 7th ITQB NOVA PhD Students’Meeting
ITQB NOVA, Lisbon, Portugal (Oeiras, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2018/01/15 - 2018/06/01 Exploring the link between the adaptation of Candida glabrata to iron excess and the yeast tolerance to fluconazole
Co-supervisor
 Biologia Celular e Molecular (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2014/03/01 - 2014/11/07 Member of the organizing committee of the 5th PhD Students’ Meeting, ITQB NOVA, Oeiras. The applicant's contribution was mainly trying to get financial support from companies and organizations, and organizing the book of abstracts. (2014/11/06 - 2014/11/07)
Meeting (Member of the Organising Committee)
 Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Association member

Society Organization name Role
2016 - 2018 COST Action CA15133 entitled “The Biogenesis of Iron-sulfur Proteins: from Cellular Biology to Molecular Aspects (FeSBionet)” Member of the Work Group 1 (“Functional analysis of the cellular machineries for the maturation of Fe/S proteins and the link to human diseases”)
Distinctions

Other distinction

2014 Travel award to attend the Young Scientists’ Forum 2014 and the FEBS/EMBO Congress “Mechanisms in Biology” (Paris, France)
2014 Travel award to attend the EMBO conference “Gene Transcription in yeast: From regulatory networks to mechanisms” (Sant Feliu de Guixols. Spain)
Gesellschaft zur Förderung der Lebenswissenschaften Heidelberg GmbH, Germany