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Noélia Duarte has a degree in Pharmaceutical Sciences (1995), MSc in Pharmaceutical Chemistry (1999), and a PhD degree in Pharmacy (2008, University of Lisbon). She is an Assistant Professor at the Faculty of Pharmacy (University of Lisbon). Teaching areas: Instrumental Methods of Analysis, Natural Products Chemistry, and Structural Identification of Organic Compounds. She has expertise in several chromatographic and spectroscopic techniques (UV, FTIR, HPLC, GC, NMR, and HPLC-MS). Noélia Duarte is an effective member of the Research Institute for Medicines - iMed.ULisboa (FFUL), and her research work has been focused on the isolation and structural characterization of bioactive compounds isolated from plants. She is also working on mass spectrometry studies applied to the identification and quantification of metabolites from plants, foods, and biological matrices. She participated in 5 research projects financed by Fundação para a Ciência e a Tecnologia (FCT). She has been the supervisor and co-supervisor of several Master theses. She is the author/co-author or co-author of 5 book chapters and 65 research papers in peer-reviewed scientific journals. Besides her teaching and scientific activities, she is also a member of the Pool of External Experts for EQAVET verification from the National Agency for Qualification and Professional Education and has carried out several audits/verification visits in compliance with the scope of the European Quality Assurance Reference Framework for Vocational Education and Training, to the Vocational Education Schools. The consultancy service consists of an auditory and verification visit and the preparation of reports for preliminary and final EQAVET verification.
Identification

Personal identification

Full name
Noélia Maria Silva Dias Duarte

Citation names

  • Duarte, Noélia
  • Duarte N

Author identifiers

Ciência ID
0F16-641D-A317
ORCID iD
0000-0003-3119-8745
Researcher Id
J-9254-2012
Scopus Author Id
15847567200

Email addresses

  • mduarte@ff.ulisboa.pt (Professional)

Telephones

Telephone
  • 217946400 Ext.: 14342 (Professional)

Addresses

  • Faculty of Pharmacy, University of Lisbon. Avenida Prof. Gama Pinto, 1649-019, Lisboa, Lisboa, Portugal (Professional)

Websites

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Proficiency (C2) Advanced (C1) Proficiency (C2)
French Beginner (A1) Intermediate (B1) Intermediate (B1) Beginner (A1)
Spanish; Castilian Elementary (A2) Advanced (C1) Beginner (A1) Intermediate (B1)
Education
Degree Classification
2008/06/11
Concluded
Farmácia (Doutoramento)
Major in Especialidade: Química Farmacêutica
Universidade de Lisboa, Portugal
"Structural Characterization and Biological Activities of Terpenic and Phenolic Compounds Isolated from Euphorbia Lagascae and Euphorbia Tuckeyana" (THESIS/DISSERTATION)
Aprovada com Distinção e Louvor
1999
Concluded
Mestrado em Química Farmacêutica (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Contribuição para o estudo do pó de cortiça e da cortiça - extracção de proantocianidinas" (THESIS/DISSERTATION)
Muito Bom
1995
Concluded
Ciências Farmacêuticas (Licenciatura)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"n/a" (THESIS/DISSERTATION)
16 valores
Affiliation

Teaching in Higher Education

Category
Host institution
Employer
2008/06/12 - Current Assistant Professor (University Teacher) Universidade de Lisboa, Portugal
1999 - 2008 Assistant (University Teacher) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal

Others

Category
Host institution
Employer
1999/01/01 - 2000/01/21 Trainee Assistant of Analitical Chemistry Universidade de Lisboa Faculdade de Farmácia, Portugal
1996/01/01 - 1998/01/01 Master Student - Master Grant (BM/6523/95), JNICT Universidade de Lisboa Faculdade de Farmácia, Portugal
1993/09/01 - 1994/09/01 Young Investigator Grant (BJI 1454), JNICT Universidade de Lisboa Faculdade de Farmácia, Portugal
Projects

Contract

Designation Funders
2017 - Current Tackling multidrug resistance in cancer: plant-derived lead compounds as P-Glycoprotein (P-gp) and breast cancer resistant protein (BCRP) modulators and colateral sensitivity agents
PTDC/MED-QUIM/30591/2017
Researcher
2023/03 - 2024/08 Exploiting monoterpene indole alkaloid derivatives for overcoming resistance in BRCA-deficient cancers. In silico characterization of binding modes
2022.05718.PTDC
Fundação para a Ciência e a Tecnologia
2017 - 2022/10 New Psychoactive Substances - A Platform for Risk Assessment of Teens Brain
PTDC/SAU-TOX/32515/2017
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2013/07 - 2015/06 Optimization of P-glycoprotein modulators and insights into the efflux mechanism
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/04 - 2014/03 Diterpenes as lead compounds for overcoming multidrug resistance in cancer cells: P-glycoprotein modulators and antiproliferative agents
Researcher
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book
  1. Duarte, Noélia. Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective. MDPI. 2023.
    Published • 10.3390/books978-3-0365-6810-2 • Editor
Book chapter
  1. Duarte, Noélia; Ramalhete, Cátia; Rijo, Patrícia; Reis, Mariana Alves; Ferreira, Maria-José U.. "Stilbenoids in Grapes and Wine". In Handbook of Dietary Phytochemicals, 1-28. Springer Singapore, 2020.
    In press • 10.1007/978-981-13-1745-3_21-1
  2. Duarte, N.; Ramalhete, C.; Lourenço, L.. "Plant Terpenoids as Lead Compounds Against Malaria and Leishmaniasis". 243-306. 2019.
    10.1016/B978-0-444-64185-4.00007-1
  3. Duarte, Noélia. "Isolation and Structural Identification of Piperine, the Major Alkaloid of Black Pepper". 2017.
    Published
  4. Duarte, Noélia. "Reversal of multidrug resistance by macrocyclic and polycyclic diterpenoids from Euphorbia species". 193-213. 2012.
    Published
  5. Ferreira, M.-J.U.; Duarte, N.-A.; Michalak, K.; Varga, A.; Molnár, J.. "Piceatannol, an antitumor compound from euphorbia lagascae seeds". 2011.
    10.1016/B978-0-12-375688-6.10054-4
Conference abstract
  1. Epole Ntungwe; Máté Vágvölgyie; Coelho, Jaime A. S.; Vera M. S. Isca; Lucília Saraiva; Diaz-Lanza Ana María; Attila Hunyadi; et al. "Chemical Composition and Biological Activity of Diterpenoids from Plectranthus mutabilis". Paper presented in 10.3390/ECMC2020-07290, 2020.
    10.3390/ecmc2020-07290
  2. Sampayo, Cristina; Carrola J; Berkowicz K; Florindo, Pedro; Moreira Rs; Perry M.J; Lopes At; et al. "Developing Tools For Metabolism Prediction Of New Psychoactive Substances ¿ Preliminary Study With Buphedrone". Paper presented in 11th iMed.ULisboa Postgraduate Students Meeting & 4th i3DU Meeting, 2019.
Conference paper
  1. Maria José U. Ferreira; Duarte, Noélia. "Searching for natural antituberculars from mozambican medicinal plants". Paper presented in Saber Tropical em Moçambique: História, Memória e Ciência, Lisboa, 2013.
Conference poster
  1. Bento-Silva, Andreia; Duarte, Noélia; Vaz Patto MC; Rocha SM; Bronze MR. "The Aroma of Traditional Broas: Shedding Light on their Volatile Composition.". 2022.
  2. Simões, Sara; Santos, Rafaela; Bento-Silva, Andreia; Santos, Marisa Viegas; Mota, Mariana; Duarte, Noélia; Sousa, Isabel; Prista, Catarina; Raymundo, Anabela. "Development of a fermented green tomato salad dressing". Paper presented in XV Encontro de Química dos Alimentos, 2021.
  3. Andreia Bento da Silva; Duarte, Noélia; Mecha E; Vaz Patto MC; Bronze MR. "Impact of the volatile composition of broa, a Portuguese ethnic maize bread, on its sensory properties.". 2021.
  4. Bento-Silva, Andreia; Duarte, Noélia; Mecha E; Vaz Patto MC; Bronze MR. "Main Volatile Compounds of Broa, a Portuguese Ethnic Maize Bread". 2021.
  5. Bento-Silva, Andreia; Duarte, Noélia; Vaz Patto MC; Bronze MR. "Hydroxycinnamic Acid Amides Present in Broa, a Traditional Ethnic Maize Bread". 2021.
  6. Duarte, Noélia; Joana Carrola; Rui Moreira; Álvaro Lopes; Cristina de Mello-Sampayo; Maria do Rosário Bronze. "Analysis of buphedrone and Phase I metabolites in mice urine". 2019.
  7. Katarzyna Berkowicz; Joana Carrola; Duarte, Noélia; Rui Moreira; Álvaro Lopes; Cristina de Mello-Sampayo; Maria do Rosário Bronze. "In vitro metabolism studies on New Psychoactive Substances: Nethylhexedrone and Buphedrone". 2019.
  8. Carreu, João; Duarte, Noélia; Maria-José U. Ferreira. "Euphorbia pubescens as a potencial source of bioactive compounds.". 2019.
  9. Carrola J; Florindo P; Moreira R; Lopes A; Duarte, Noélia; de Mello-Sampayo C; Bronze MR. "Developing tools for metabolism prediction of New Psychoactive Substances – Buphedrone". 2019.
  10. Henriques, Sara C; Schultz, Anna-Lena; Florindo, Pedro; Moreira, Rui; Lopes, Álvaro; Duarte, Noélia; Bronze, Maria do Rosário; De Mello-Sampayo, Cristina. "Metabolism studies on emerging synthetic cathinones". Paper presented in 9th iMed.ULisboa Postgraduate Students Meeting & 2nd i3du Meeting, Lisbon, Portugal, 2017.
  11. Lourenço L; Duarte, Noélia; Maria-José U. Ferreira. "Euphorbia species as a source of new bioactive diterpenes.". 2017.
Journal article
  1. Bruno Gonçalves; Duarte, Noélia; Ramalhete, Cátia; Madureira, Ana Margarida ; Ferreira, Maria-Jose U.. Corresponding author: Ferreira, Maria-Jose U.. "Tabernaemontana-indol alkaloids in cancer". Phytochemistry Reviews (2024):
    Submitted
  2. Célia Faustino; Noélia Duarte; Lídia Pinheiro. "Triterpenes Drug Delivery Systems, a Modern Approach for Arthritis Targeted Therapy". Pharmaceuticals (2023): https://doi.org/10.3390/ph17010054.
    10.3390/ph17010054
  3. Eduarda Mendes; Cátia Ramalhete; Noélia Duarte. "Myrsinane-Type Diterpenes: A Comprehensive Review on Structural Diversity, Chemistry and Biological Activities". International Journal of Molecular Sciences 25 (2023): 147. https://doi.org/10.3390/ijms25010147.
    Open access • Published • 10.3390/ijms25010147
  4. Joana Chambel Coelho; Noélia Duarte; Andreia Bento da Silva; Maria do Rosário Bronze; Lisa Alexandra Mestrinho. "Placebo-Controlled Trial of Daily Oral Cannabidiol as Adjunctive Treatment for Cats with Chronic Gingivostomatitis". Animals (2023): https://doi.org/10.3390/ani13172716.
    10.3390/ani13172716
  5. Célia Faustino; Lídia Pinheiro; Noélia Duarte. "Triterpenes as Potential Drug Candidates for Rheumatoid Arthritis Treatment". Life (2023): https://doi.org/10.3390/life13071514.
    10.3390/life13071514
  6. Noélia Duarte. "Special Issue on Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective". Pharmaceuticals (2022): https://doi.org/10.3390/ph15101249.
    10.3390/ph15101249
  7. Andreia Bento-Silva; Noélia Duarte; Magda Santos; Carina Pedrosa Costa; Maria Carlota Vaz Patto; Sílvia M. Rocha; Maria Rosário Bronze. "Comprehensive Two-Dimensional Gas Chromatography as a Powerful Strategy for the Exploration of Broas Volatile Composition". Molecules (2022): https://doi.org/10.3390/molecules27092728.
    10.3390/molecules27092728
  8. Sara Simões; Rafaela Santos; Andreia Bento-Silva; Marisa V Santos; Mariana Mota; Noélia Duarte; Isabel Sousa; Anabela Raymundo; Catarina Prista. "Improving nutritional quality of unripe tomato through fermentation by a consortium of yeast and lactic acid bacteria". Journal of the Science of Food and Agriculture (2022): https://doi.org/10.1002/jsfa.11476.
    10.1002/jsfa.11476
  9. Raquel Durão; Cátia Ramalhete; Ana Margarida Madureira; Eduarda Mendes; Noélia Duarte. "Plant Terpenoids as Hit Compounds against Trypanosomiasis". Pharmaceuticals 15 3 (2022): 340-340. https://doi.org/10.3390/ph15030340.
    10.3390/ph15030340
  10. Oliverio, Manuela; Bulotta, Stefania; Duarte, Noélia. "Editorial: Nature Inspired Protective Agents Against Oxidative Stress". Frontiers in Pharmacology 13 (2022): http://dx.doi.org/10.3389/fphar.2022.859549.
    Open access • Published • 10.3389/fphar.2022.859549
  11. Ramalhete, Cátia; Bruno M. F. Goncalves; Barbosa, Filipa; Duarte, Noélia; Ferreira, Maria-José U.. "Momordica balsamina: phytochemistry and pharmacological potential of a gifted species". Phytochemistry Reviews (2022): http://dx.doi.org/10.1007/s11101-022-09802-7.
    10.1007/s11101-022-09802-7
  12. Andreia Bento-Silva; Noélia Duarte; Maria Belo; Elsa Mecha; Bruna Carbas; Carla Brites; Maria Carlota Vaz Patto; Maria Rosário Bronze. "Shedding Light on the Volatile Composition of Broa, a Traditional Portuguese Maize Bread". Biomolecules (2021): https://doi.org/10.3390/biom11101396.
    10.3390/biom11101396
  13. Ana Henriques Mota; Inês Prazeres; Henrique Mestre; Andreia Bento-Silva; Maria João Rodrigues; Noélia Duarte; Ana Teresa Serra; et al. "A Newfangled Collagenase Inhibitor Topical Formulation Based on Ethosomes with Sambucus nigra L. Extract". Pharmaceuticals 14 5 (2021): 467-467. https://doi.org/10.3390/ph14050467.
    10.3390/ph14050467
  14. Andreia Bento-Silva; Noélia Duarte; Elsa Mecha; Maria Belo; Ana Teresa Serra; Maria Carlota Vaz Patto; Maria Rosário Bronze. "Broa, an Ethnic Maize Bread, as a Source of Phenolic Compounds". Antioxidants (2021): https://doi.org/10.3390/antiox10050672.
    10.3390/antiox10050672
  15. Epole Ntungwe; Eva María Domínguez-Martín; Catarina Teodósio; Silvia Teixidó-Trujillo; Natalia Armas Capote; Lucilia Saraiva; Ana María Díaz-Lanza; Noélia Duarte; Patrícia Rijo. "Preliminary Biological Activity Screening of Plectranthus spp. Extracts for the Search of Anticancer Lead Molecules". Pharmaceuticals (2021): https://doi.org/10.3390/ph14050402.
    10.3390/ph14050402
  16. Mendes, Eduarda; Duarte, Noélia; Eduarda Mendes; Noélia Duarte. "Mid-Infrared Spectroscopy as a Valuable Tool to Tackle Food Analysis: A Literature Review on Coffee, Dairies, Honey, Olive Oil and Wine". Foods 10 2 (2021): 477-477. http://dx.doi.org/10.3390/foods10020477.
    Open access • Published • 10.3390/foods10020477
  17. Ana Henriques Mota; Noélia Duarte; Ana Teresa Serra; António Ferreira; Maria Rosário Bronze; Luísa Custódio; Maria Manuela Gaspar; et al. "Further Evidence of Possible Therapeutic Uses of Sambucus nigra L. Extracts by the Assessment of the In Vitro and In Vivo Anti-Inflammatory Properties of Its PLGA and PCL-Based Nanoformulations". Pharmaceutics 12 12 (2020): 1181-1181. https://doi.org/10.3390/pharmaceutics12121181.
    10.3390/pharmaceutics12121181
  18. Garcia, Catarina; Isca, Vera M. S.; Pereira, Filipe; Monteiro, Carlos M.; Ntungwe, Epole; Sousa, Francisco; Dinic, Jelena; et al. "Royleanone Derivatives From Plectranthus spp. as a Novel Class of P-Glycoprotein Inhibitors". Frontiers in Pharmacology 11 557789 (2020): http://dx.doi.org/10.3389/fphar.2020.557789.
    Open access • Published • 10.3389/fphar.2020.557789
  19. Andreia Bento-Silva; Noélia Duarte; Elsa Mecha; Maria Belo; Maria Carlota Vaz Patto; Maria do Rosário Bronze. "Hydroxycinnamic Acids and Their Derivatives in Broa, a Traditional Ethnic Maize Bread". Foods 9 10 (2020): 1471-1471. https://doi.org/10.3390/foods9101471.
    10.3390/foods9101471
  20. Mota, Ana Henriques; Andrade, Joana M.; Rodrigues, Maria João; Custódio, Luísa; Bronze, Maria Rosário; Duarte, Noélia; Baby, André; et al. "Synchronous insight of in vitro and in vivo biological activities of Sambucus nigra L. extracts for industrial uses". Industrial Crops and Products 154 (2020): 112709. http://dx.doi.org/10.1016/j.indcrop.2020.112709.
    10.1016/j.indcrop.2020.112709
  21. Vera M. S. Isca; Joana Andrade; Ana Sofia Fernandes; Paulo Paixão; Clara Uriel; Ana María Gómez; Noélia Duarte; Patrícia Rijo. "In Vitro Antimicrobial Activity of Isopimarane-Type Diterpenoids". Molecules (2020): https://doi.org/10.3390/molecules25184250.
    10.3390/molecules25184250
  22. Adeoye, Oluwatomide; Bártolo, Inês; Conceição, Jaime; da Silva, Andreia Bento; Duarte, Noélia; Paula Francisco, Ana; Taveira, Nuno; Cabral-Marques, Helena. "Pyromellitic dianhydride crosslinked soluble cyclodextrin polymers: Synthesis, lopinavir release from sub-micron sized particles and anti-HIV-1 activity". International Journal of Pharmaceutics (2020): 119356. http://dx.doi.org/10.1016/j.ijpharm.2020.119356.
    10.1016/j.ijpharm.2020.119356
  23. Faustino, C.; Martins, T.; Duarte, N.; Ribeiro, M.H.. "Self-Assembly of Lipoaminoacids-DNA Based on Thermodynamic and Aggregation Properties". Journal of Surfactants and Detergents (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85078655818&partnerID=MN8TOARS.
    10.1002/jsde.12391
  24. Adeoye, O.; Conceição, J.; Serra, P.A.; Bento da Silva, A.; Duarte, N.; Guedes, R.C.; Corvo, M.C.; et al. "Cyclodextrin solubilization and complexation of antiretroviral drug lopinavir: In silico prediction; Effects of derivatization, molar ratio and preparation method". Carbohydrate Polymers 227 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85072659617&partnerID=MN8TOARS.
    10.1016/j.carbpol.2019.115287
  25. Ana Marta Matos; Reis, Mariana Alves; Duarte, Noélia; Ricardo Ferreira; Ferreira, Maria-Jose U.. "Epoxylathyrane derivatives as MDR-selective compounds for disabling multidrug resistance in cancer". Frontiers in Pharmacology 11 (2020): 519.
    Open access • Published • 10.3389/fphar.2020.00599
  26. Carrola, J.; Duarte, Noélia; Florindo, P.; Henriques, S.; da Silva, G.; Bijlsma, L.; Moreira, R.; et al. "Metabolism of N-ethylhexedrone and buphedrone: An in vivo study in mice using HPLC-MS/MS". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1159 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85090272900&partnerID=MN8TOARS.
    10.1016/j.jchromb.2020.122340
  27. Catarina Garcia; Epole Ntungwe; Ana Rebelo; Bessa, C.; Tijana Stankovic; Jelena Dinic; Díaz Lanza Ana M.; et al. "Parvifloron D from Plectranthus strigosus: Cytotoxicity Screening of Plectranthus spp. Extracts". Biomolecules (2019): https://www.mdpi.com/2218-273X/9/10/616.
    10.3390/biom9100616
  28. Faustino, Celia; Francisco, Ana Paula; Isca, Vera M. S.; Duarte, Noelia. "Cytotoxic Stilbenes and Derivatives as Promising Antimitotic Leads for Cancer Therapy". Current pharmaceutical design (2019): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:30636588&KeyUID=MEDLINE:30636588.
    10.2174/1381612825666190111123959
  29. Garcia, Catarina; Teodosio, Catarina; Oliveira, Carolina; Oliveira, Claudia; Diaz-Lanza, Ana; Reis, Catarina; Duarte, Noelia; Rijo, Patricia. "Naturally occurring Plectranthus-derived diterpenes with antitumoral activities". Current pharmaceutical design (2019): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:30644340&KeyUID=MEDLINE:30644340.
    10.2174/1381612825666190115144241
  30. Neto, S.; Duarte, Noélia; Pedro, C.; Spengler, G.; Molnár, J.; Ferreira, M.-J.U.. "Effective MDR reversers through phytochemical study of Euphorbia boetica". Phytochemical Analysis 30 5 (2019): 498-511. http://www.scopus.com/inward/record.url?eid=2-s2.0-85067440956&partnerID=MN8TOARS.
    10.1002/pca.2841
  31. Roque, Luis; Duarte, Noelia; Bronze, Maria Rosario; Garcia, Catarina; Alopaeus, Julia; Molpeceres, Jesus; Hagesaether, Ellen; et al. "Development of a bioadhesive nanoformulation with Glycyrrhiza glabra L. extract against Candida albicans". Biofouling (2018): 1-13. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:30362371&KeyUID=MEDLINE:30362371.
    10.1080/08927014.2018.1514391
  32. Mónico, A.; Nim, S.; Duarte, Noélia; Rawal, M.K.; Prasad, R.; Di Pietro, A.; Ferreira, M.-J.U.. "Lathyrol and epoxylathyrol derivatives: Modulation of Cdr1p and Mdr1p drug-efflux transporters of Candida albicans in Saccharomyces cerevisiae model". Bioorganic and Medicinal Chemistry 25 13 (2017): 3278-3284. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018347859&partnerID=MN8TOARS.
    10.1016/j.bmc.2017.04.016
  33. Nim, S.; Mónico, A.; Rawal, M.K.; Duarte, Noélia; Prasad, R.; Di Pietro, A.; Ferreira, M.-J.U.. "Overcoming Multidrug Resistance in Candida albicans: Macrocyclic Diterpenes from Euphorbia Species as Potent Inhibitors of Drug Efflux Pumps". Planta Medica (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84965006976&partnerID=MN8TOARS.
    10.1055/s-0042-106169
  34. Wisniewski, J.; Wesolowska, O.; Sroda-Pomianek, K.; Paprocka, M.; Bielawska-Pohl, A.; Krawczenko, A.; Duarte, Noélia; et al. "Euphorbia species-derived diterpenes and coumarins as multidrug resistance modulators in human colon carcinoma cells". Anticancer Research 36 5 (2016): 2259-2264. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017889260&partnerID=MN8TOARS.
  35. Matos, A.M.; Reis, M.; Duarte, Noélia; Spengler, G.; Molnár, J.; Ferreira, M.-J.U.. "Epoxylathyrol Derivatives: Modulation of ABCB1-Mediated Multidrug Resistance in Human Colon Adenocarcinoma and Mouse T-Lymphoma Cells". Journal of Natural Products 78 9 (2015): 2215-2228. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942693549&partnerID=MN8TOARS.
    10.1021/acs.jnatprod.5b00370
  36. Baptista, R.; Madureira, A.M.; Jorge, R.; Adão, R.; Duarte, A.; Duarte, N.; Lopes, M.M.; Teixeira, G.. "Antioxidant and antimycotic activities of two native Lavandula species from Portugal". Evidence-based Complementary and Alternative Medicine 2015 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84928485652&partnerID=MN8TOARS.
    10.1155/2015/570521
  37. Vieira, C.; Duarte, Noélia; Reis, M.A.; Spengler, G.; Madureira, A.M.; Molnár, J.; Ferreira, M.-J.U.. "Improving the MDR reversal activity of 6,17-epoxylathyrane diterpenes". Bioorganic and Medicinal Chemistry 22 22 (2014): 6392-6400. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908377069&partnerID=MN8TOARS.
    10.1016/j.bmc.2014.09.041
  38. Ferreira, M.-J.U.; Duarte, Noélia; Reis, M.; Madureira, A.M.; Molnár, J.. "Euphorbia and Momordica metabolites for overcoming multidrug resistance". Phytochemistry Reviews 13 4 (2014): 915-935. http://www.scopus.com/inward/record.url?eid=2-s2.0-84912045745&partnerID=MN8TOARS.
    10.1007/s11101-014-9342-8
  39. Luo, X.; Pires, D.; Aínsa, J.A.; Gracia, B.; Duarte, N.; Mulhovo, S.; Anes, E.; Ferreira, M.-J.U.. "Zanthoxylum capense constituents with antimycobacterial activity against Mycobacterium tuberculosis in vitro and ex vivo within human macrophages". Journal of Ethnopharmacology 146 1 (2013): 417-422. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874112005&partnerID=MN8TOARS.
    10.1016/j.jep.2013.01.013
  40. Luo, X.; Pedro, L.; Milic, V.; Mulhovo, S.; Duarte, A.; Duarte, N.; Ferreira, M.-J.U.. "Antibacterial benzofuran neolignans and benzophenanthridine alkaloids from the roots of Zanthoxylum capense". Planta Medica 78 2 (2012): 148-153. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856270569&partnerID=MN8TOARS.
    10.1055/s-0031-1280289
  41. Reis, M.; Ferreira, R.J.; Serly, J.; Duarte, Noélia; Madureira, A.M.; Santos, D.J.V.A.; Molnár, J.; Ferreira, M.-J.U.. "Colon adenocarcinoma multidrug resistance reverted by Euphorbia diterpenes: Structure-activity relationships and pharmacophore modeling". Anti-Cancer Agents in Medicinal Chemistry 12 9 (2012): 1015-1024. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872231481&partnerID=MN8TOARS.
    10.2174/187152012803529655
  42. Valente, I.; Reis, M.; Duarte, Noélia; Serly, J.; Molnár, J.; Ferreira, M.-J.U.. "Jatrophane diterpenes from euphorbia mellifera and their activity as P-glycoprotein modulators on multidrug-resistant mouse lymphoma and human colon adenocarcinoma cells". Journal of Natural Products 75 11 (2012): 1915-1921. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870204747&partnerID=MN8TOARS.
    10.1021/np3004003
  43. Wesolowska, O.; Wisniewski, J.; Sroda-Pomianek, K.; Bielawska-Pohl, A.; Paprocka, M.; Dus, D.; Duarte, N.; Ferreira, M.-J.U.; Michalak, K.. "Multidrug resistance reversal and apoptosis induction in human colon cancer cells by some flavonoids present in citrus plants". Journal of Natural Products 75 11 (2012): 1896-1902. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870216847&partnerID=MN8TOARS.
    10.1021/np3003468
  44. Wesolowska, O.; Wisniewski, J.; Bielawska-Pohl, A.; Paprocka, M.; Duarte, N.; Ferreira, M.-J.U.; Dus, D.; Michalak, K.. "Stilbenes as multidrug resistance modulators and apoptosis inducers in human adenocarcinoma cells". Anticancer Research 30 11 (2010): 4587-4593. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650252900&partnerID=MN8TOARS.
  45. Lage, H.; Duarte, N.; Coburger, C.; Hilgeroth, A.; Ferreira, M.J.U.. "Antitumor activity of terpenoids against classical and atypical multidrug resistant cancer cells". Phytomedicine 17 6 (2010): 441-448. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950297689&partnerID=MN8TOARS.
    10.1016/j.phymed.2009.07.009
  46. Pusztai, R.; Abrantes, M.; Sherly, J.; Duarte, N.; Molnar, J.; Ferreira, M.-J.U.. "Antitumor-promoting activity of lignans: Inhibition of human cytomegalovirus IE gene expression". Anticancer Research 30 2 (2010): 451-454. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950544499&partnerID=MN8TOARS.
  47. Duarte, N.; Lage, H.; Abrantes, M.; Ferreira, M.-J.U.. "Phenolic compounds as selective antineoplasic agents against multidrug-resistant human cancer cells". Planta Medica 76 10 (2010): 975-980. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954916701&partnerID=MN8TOARS.
    10.1055/s-0029-1240892
  48. Spengler, G.; Ramalhete, C.; Martins, M.; Martins, A.; Serly, J.; Viveiros, M.; Molnár, J.; et al. "Evaluation of cucurbitane-type triterpenoids from Momordica balsamina on P-glycoprotein (ABCB1) by flow cytometry and real-time fluorometry". Anticancer Research 29 10 (2009): 3989-3993. http://www.scopus.com/inward/record.url?eid=2-s2.0-71949083688&partnerID=MN8TOARS.
  49. Teisseyre, A.; Duarte, N.; Ferreira, M.-J.U.; Michalak, K.. "Influence of the multidrug transporter inhibitors on the activity of KV1.3 voltage-gated potassium channels". Journal of Physiology and Pharmacology 60 1 (2009): 69-76. http://www.scopus.com/inward/record.url?eid=2-s2.0-65949088566&partnerID=MN8TOARS.
  50. Duarte, N.; Ramalhete, C.; Varga, A.; Molnár, J.; Ferreira, M.-J.U.; Duarte, Noélia; Ramalhete, Cátia; et al. "Multidrug resistance modulation and apoptosis induction of cancer cells by terpenic compounds isolated from Euphorbia species". Anticancer Research 29 11 (2009): 4467-4472. http://www.scopus.com/inward/record.url?eid=2-s2.0-75149181690&partnerID=MN8TOARS.
  51. Duarte, N.; Lage, H.; Ferreira, M.-J.U.; Duarte, Noelia; Lage, Hermann; Ferreira, Maria-Jose U.. "Three new jatrophane polyesters and antiproliferative constituents from Euphorbia tuckeyana". Planta Medica 74 1 (2008): 61-68. http://www.scopus.com/inward/record.url?eid=2-s2.0-39149087948&partnerID=MN8TOARS.
    10.1055/s-2007-993765
  52. Duarte, N.; Ferreira, M.-J.U.; Martins, M.; Viveiros, M.; Amaral, L.. "Antibacterial activity of ergosterol peroxide against Mycobacterium tuberculosis: Dependence upon system and medium employed". Phytotherapy Research 21 7 (2007): 601-604. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447558018&partnerID=MN8TOARS.
    10.1002/ptr.2119
  53. Duarte, N.; Varga, A.; Cherepnev, G.; Radics, R.; Molnár, J.; Ferreira, M.-J.U.; Duarte, Noelia; et al. "Apoptosis induction and modulation of P-glycoprotein mediated multidrug resistance by new macrocyclic lathyrane-type diterpenoids". Bioorganic and Medicinal Chemistry 15 1 (2007): 546-554. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750953574&partnerID=MN8TOARS.
    10.1016/j.bmc.2006.09.028
  54. Duarte, N.; Ferreira, M.-J.U.. "Lagaspholones A and B: Two new jatropholane-type diterpenes from euphorbia iagascae". Organic Letters 9 3 (2007): 489-492. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847079662&partnerID=MN8TOARS.
    10.1021/ol062854f
  55. Pusztai, R.; Ferreira, M.-J.U.; Duarte, N.; Engi, H.; Molnar, J.. "Macrocyclic lathyrane diterpenes as antitumor promoters". Anticancer Research 27 1 A (2007): 201-206. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847658888&partnerID=MN8TOARS.
  56. Duarte, N.; Gyémánt, N.; Abreu, P.M.; Molnár, J.; Ferreira, M.J.U.. "New macrocyclic lathyrane diterpenes, from Euphorbia lagascae, as inhibitors of multidrug resistance of tumour cells". Planta Medica 72 2 (2006): 162-168. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644534548&partnerID=MN8TOARS.
    10.1055/s-2005-873196
  57. Da Silva Dias Duarte, N.M.; Do Nascimento, J.M.. "Pharmacological actions of proanthocyanidins". Revista Portuguesa de Farmacia 48 1 (1998): 9-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344972877&partnerID=MN8TOARS.
  58. Tavares, O.S.; Duarte, N.D.; Cunha, S.O.; Ascenso, J.R.; Ferreira, M.J.U.. "Triterpenoids from Euphorbia boetica". Fitoterapia 66 6 (1995): 551-552. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029558311&partnerID=MN8TOARS.
Report
  1. Cavaco, Marco; Mateus, Maria Luísa Andrade, 1962-; Duarte, Noélia Maria da Silva Dias, 1970-. 2012. Pesquisa de resíduos de pesticidas em saladas prontas a consumir. http://hdl.handle.net/10451/7718.
Thesis / Dissertation
  1. Duarte, Noélia Maria da Silva Dias, 1970-. "Structural characterization and biological activities of terpenic and phenolic compounds isolated from Euphorbia lagascae and Euphorbia tuckeyana". PhD, 2008. http://sibul.reitoria.ul.pt/F/?func=item-global&doc_library=ULB01&type=03&doc_number=000531328.
  2. Duarte, Noélia. "Contribuição para o estudo do pó de cortiça e da cortiça - extracção de proantocianidinas". Master, Universidade de Lisboa Faculdade de Farmácia, 1999.

Other

Other output
  1. ANTICANCER PROPERTIES AND MDR MODULATORY EFFECT OF PLANT POLYPHENOLS AND THEIR INTERACTION WITH MEMBRANE COMPONENTS. 2008. Michalak, Krystyna; Wesolowska, Olga; Wisniewski, Jerzy; Sroda, Kamila; Teisseyre, Andrzej; Kuzdzal, Michal; Strancar, Janez; Duarte, Noelia; Ferreira, Maria-Jose U.. http://hdl.handle.net/10451/21654.
  2. ANTINEOPLASIC ACTIVITY OF PHENOLIC COMPOUNDS AGAINST SENSITIVE AND RESISTANT HUMAN CANCER CELLS. 2008. Duarte, Noelia; Lage, Hermann; Ferreira, Maria-Jose U.. http://hdl.handle.net/10451/21447.
  3. MACROCYCLIC DITERPENES AS LEAD COMPOUNDS FOR THE DEVELOPMENT OF P-GLYCOPROTEIN MODULATORS IN MULTIDRUG-RESISTANT CANCER CELLS. 2008. Ferreira, Maria-Jose U.; Duarte, Noelia; Jardanhazy, Anett; Madureira, Ana-Margarida; Ramalhete, Catia; Ocsovszki, Imre; Molnar, Joseph. http://hdl.handle.net/10451/20933.
  4. Macrocyclic lathyrane and jatrophane diterpenes as P-glycoprotein modulators in multi-drug-resistant cancer cells. 2008. Ferreira, MJU; Duarte, Noélia; Járdánházy, Anett; Madureira, AM; Ramalhete, C; Molnar, Joseph. http://hdl.handle.net/10451/22003.
  5. Antiplasmodial Activity of Lignans and Extracts from Pycnanthus angolensis. The dichloromethane, methanol and aqueous ethanol extracts of the stem bark of Pycnanthus angolensis were evaluated for their in vitro activity against the 3D7 Plasmodium falciparum strain. The CH2Cl2 extract was the most active showing an IC50 = 1.6 mu g/mL. From this extract, a new dibenzylbutane lignan, threo-4,4'-dihydroxy-3-methoxylignan (1) named pycnantolol, together with the known lignans. 2008. Abrantes, Marta; Mill-Homens, Tania; Duarte, Noelia; Lopes, Dinora; Cravo, Pedro; Madureira, Maria do Ceu; Ferreira, Maria-Jose U.; et al. http://hdl.handle.net/10451/21446.
    http://dx.doi.org/10.1055/s-2008-1081317
  6. Synergistic interaction between p-glycoprotein modulators and epirubicine on resistant cancer cells. The macrocyclic lathyrane diterpene latilagascene B, previously isolated from Euphorbia lagascae, was acylated to afford three new diterpene esters, latilagascenes G (1), H (2), and I (3), whose structures were assigned by spectroscopic methods. These acyl derivatives, and the macrocyclic diterpenes of the jatro-phane-type, tuckeyanols A (4) and B (5), and euphotuckeyanol (6), isolated from Euphor. 2008. Duarte, Noelia; Jardanhazy, Anett; Molnar, Joseph; Hilgeroth, Andreas; Ferreira, Maria-Jose U.; Duarte, N.; Járdánházy, A.; et al. http://hdl.handle.net/10451/21445.
    http://dx.doi.org/10.1016/j.bmc.2008.08.071
  7. Antileishmanial activity of piceatannol isolated from Euphorbia lagascae seeds. In the search for biologically active compounds from Euphorbia lagascae Spreng, an herbaceous plant native to southeast of Iberic Peninsula, a stilbene, two coumarins and two 1-2-deoxyphorbol diterpene esters were isolated by chromatographic methods, from the methanol extracts of its defatted seeds. The structures of these compounds were elucidated by a combination of physical and spectral data (I. 2008. Duarte, Noelia; Kayser, Oliver; Abreu, Pedro; Ferreira, Maria-Jose U.; Duarte, N.; Kayser, O.; Abreu, P.; Ferreira, M.J.U.. http://hdl.handle.net/10451/21649.
    http://dx.doi.org/10.1002/ptr.2334
  8. Lagaspholones A and B. Two new diterpenes, lagaspholones A (1) and B (2), have been isolated from the methanolic extract of Euphorbia lagascae, along with the known compounds (+)-dehydrovomifoliol, scopoletin, dehydrodiconiferyl diacetate, 3-indolcarbaldehyde, and 4-hydroxy-3,5-dimethoxybenzaldehyde. Their structures were elucidated by spectroscopic methods. Compounds 1 and 2 contain the rare jatropholane-type skeleton,. 2007. Duarte, Noelia; Ferreira, Maria-Jose U.. http://hdl.handle.net/10451/21438.
    http://dx.doi.org/10.1021/ol062854f
  9. Antibacterial activity of ergosterol peroxide against Mycobacterium tuberculosis. Ergosterol peroxide, cycloart-23-en-3 beta,25-diol, vanillin and 4-hydroxybenzaldehyde have been isolated and characterized from a crude methanol extract of Euphorbia lagascae. Previous studies have shown contradictory results about the antibacterial activity of ergosterol peroxide against Mycobacterium tuberculosis. In order to clarify this question, the activity of this compound was tested again. 2007. Duarte, Noelia; Ferreira, Maria-Jose U.; Martins, Marta; Viveiros, Miguel; Amaral, Leonard. http://hdl.handle.net/10451/21440.
    http://dx.doi.org/10.1002/ptr.2119
  10. Interaction between doxorubicin and the resistance modifier stilbene on multidrug resistant mouse lymphoma and human breast cancer cells. The hydroxystilbene trans-3,5,3,4-tetrahydroxystilbene (piceatannol) (1), isolated from the methanol extract of Euphorbia lagascae defatted seeds, was methylated to yield the derivatives trans-3,5,3,4'-tetramethoxystilbene (2), (trans-3,5-dihydroxy-3', 4'-dimethoxystilbene) (3) and trans-3,5,3'-trihydroxy4'-methoxystilbene (4). The structures of the compounds were assigned by spectroscopic methods. 2006. Ferreira, Maria-Jose U.; Duarte, Noelia; Gyemant, Nora; Radics, Rita; Cherepnev, Georgy; Varga, Andras; Molnar, Joseph; et al. http://hdl.handle.net/10451/21436.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/12/18 Bento-Silva A, Duarte N, Vaz Patto MC, Rocha SM, Bronze MR. Volatile terpenic compounds: possible influence on the aroma of broas? 13th Encontro Nacional de Cromatografia, 17th-19th December 2023, Lisbon, Portugal.
Sociedade Portuguesa de Química (Lisboa, Portugal)
2022/12/06 Bento-Silva A, Duarte N, Santos M, Costa CP, MC Vaz Patto, Rocha SM, Bronze MR (2022). The Potential of Comprehensive Two-Dimensional Gas Chromatography in the Disclosure of Broas Volatile Composition. 12th Encontro Nacional de Cromatografia, 05th-08th December 2022, Aveiro, Portugal.
Sociedade Portuguesa de Química (Aveiro, Portugal)
2022 Bento-Silva A, Duarte N, Santos M, Costa CP, MC Vaz Patto, Rocha SM, Bronze MR (2022). Unraveling the metabolites of N-ethylpentylone in mice serum and urine. 12th Encontro Nacional de Cromatografia, 05th-08th December 2022, Aveiro, Portugal. 12th Encontro Nacional de Cromatografia
Sociedade Portuguesa de Química (Aveiro, Portugal)
2021/12/17 Bento-Silva A, Duarte N, Mecha E, Belo M, Vaz Patto MC, Bronze MR. Valorisation of broas and Portuguese maize varieties: the useful contribution of chromatographic techniques. Chromatography helps in times of crisis (SPQ), 17th December 2021.
Sociedade Portuguesa de Química
2019/10/09 HPLC-ESI-MS/MS as a valuable to unravel the metabolism of new psychoactive substances 1st Iberian Meeting in Separation Sciences & Mass Spectrometry
(Santiago de Compostela, Spain)
2019/10 Studies on the metabolism of synthetic cathinones N-ethylhexedrone and buphedrone using liquid chromatography-mass spectrometry (LC-MS/MS) Lisbon Addictions 2019 - Third European Conference on Addictive Behaviours and Dependencies
(LIsboa, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2024 - Current O efeito dos psicadélicos nas doenças inflamatórias crónicas
Supervisor
Mestrado Integrado em Ciências Farmacêuticas (Master)
2024 - Current Síndroma metabólico: Etiologia ou tratamento
Supervisor
2024 - Current Potencial terapêutico da psilocibina
Supervisor
2024 - Current Abordagens terapêuticas na menopausa
Supervisor
2024 - Current Diabetes Melitus: estratégias de prevenção e terapêutica
Supervisor
2023/10 - Current Olea europaea: biological potential of an ancient tree
Supervisor
Mestrado em Qualidade Alimentar e Saúde (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/10 - Current Assessing the nutritional and phytochemical composition of novel fermented products: Focus in Lathyrus sativus L.
Co-supervisor
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/10 - Current Characterization of national olive oils
Co-supervisor
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/11 - Current O paradigma dos alimentos saudáveis – avaliação das propriedades funcionais e da atividade antimicrobiana de adoçantes naturais comercializados em Portugal.
Co-supervisor
Mestrado em Qualidade Alimentar e Saúde (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/02 - 2023/12 O papel dos produtos naturais na medicina moderna
Supervisor
2023/02 - 2023/12 Doença Pulmonar Obstrutiva Crónica: Novas Abordagens Terapêuticas
Supervisor
2022/10 - 2023/11 Exploring silicone functionalization with surfactin towards the improvement of medical devices antimicrobial properties
Co-supervisor
Mestrado em Química medicinal e Biofarmacêutica (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/02 - 2023/10 3-hydroxy-V-coumarin hydrolysis study through fluorometry and LC-MS analysis
Co-supervisor
2023/02 - 2023/10 3-Hydroxy-V-coumarin sulfonation and LC-MS analysis
Co-supervisor
2023/02 - 2023/07 Doenças Tropicais Negligenciadas
Supervisor
2023/02 - 2023/07 Infeções associadas aos cuidados de saúde
Supervisor
2022/02 - 2022/11 LC-MS/MS method development for anti-oxidative biomarkers
Co-supervisor
2022/02 - 2022/07 Prevenção e terapêutica das infeções nosocomiais
Supervisor
2018 - 2020 Bioactive terpenoids from Euphorbia pubescens: isolation and derivatization
Supervisor of João Paulo Magalhães Carréu
Mestrado em Química Farmacêutica e Terapêutica (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017 - 2019 Formulation of carotenoids as natural preservatives and colorants in food industry
Co-supervisor of Patrícia Isabel Gonçalves Oliveira
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017 - 2019 Actividade antibacteriana dos constituintes químicos da planta medicinal africana Grewia hexamita contra bactérias resistentes
Co-supervisor of Sara Filipa Santos Jogo
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015 - 2017 Development of a small library of bioactive compounds through isolation and molecular derivatization
Co-supervisor of João Nuno Gomes
Mestrado em Química Farmacêutica e Terapêutica (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014 - 2015 Pesquisa de Compostos com Atividade Antiproliferativa de Plantas Medicinais Africanas
Co-supervisor of Jorge Silva
Universidade de Lisboa Faculdade de Farmácia, Portugal
2012 - 2014 Anticancer Properties of terpenoids in resistant cancer cells
Co-supervisor of Sara Neto
Universidade de Lisboa Faculdade de Farmácia, Portugal
2012 - 2013 Development of a small library of macrocyclic diterpenes through molecular derivatization
Co-supervisor of Ana Marta de Matos
Universidade de Lisboa Faculdade de Farmácia, Portugal
2012/01 - 2012/05 Isolation and structure characterization of potential bioactive compounds from Euphorbia boetica
Supervisor of Giorgio Daniotti
Università degli Studi di Pavia, Italy
2011 - 2012 Compostos bioativos isolados de Euphorbia boetica – Modulação da glicoproteína-P
Co-supervisor of Cátia Vicente Vieira
Universidade de Lisboa Faculdade de Farmácia, Portugal
2011 - 2012 Pesquisa de resíduos de pesticidas em saladas prontas a consumir
Co-supervisor of Marco Calvinho Cavaco
2010 - 2011 Pesquisa de metabolitos secundários bioativos a partir de espécies do género Euphorbia
Supervisor of Catarina Sofia Feliciano Pires
2008 - 2009 Pesquisa de compostos com atividade moduladora da multirresistência em células tumorais
Co-supervisor of Ana Rita Martins Angelino

Event organisation

Event name
Type of event (Role)
Institution / Organization
2023/12/16 - Current Short Course - EXPLORING DRUG METABOLISM: THE ROLE OF LC-MS/MS ANALYSIS. The course will explore the potentialities of UHPLC-MS/MS to gain a better understanding of drug absorption, distribution, metabolism, excretion, and toxicology (ADMET). Participants will work on a case-study aiming to identify the metabolites of a new illicit drug, envisioning the detection of drug consumption in routine drug screening. The course will provide an overview of UHPLC-MS/MS (triple quadrupole) analysis and describe several applications. (2023 - 2023)
Seminar (Co-organisor)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/12/17 - 2023/12/19 13º Encontro Nacional de Cromatografia This event is intended to create an atmosphere of good interaction and networking among the Portuguese chromatography communities and will provide a unique opportunity for the exchange of scientific knowledge between researchers and specialists from academia, companies, laboratories, and institutions that use chromatography as a component of their analytical workflow. (2023/12/17 - 2023/12/17)
Meeting (Member of the Organising Committee)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/07/28 - 2019/07/31 Natural Products in Drug Discovery and Human Health (NatProdDDH) (2019/07/28 - 2019/07/31)
Congress (Member of the Organising Committee)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2024/03/04 Green strategies to extract and formulate natural-based pigments: from red to blue hues
(Thesis) Main arguer
Ana Nunes Nunes (PhD)
Universidade Nova de Lisboa, Portugal
2023/12/15 Estudos de ocorrência de microplásticos nos sistemas de abastecimento da EPAL e de AdVT e potencial impacte na saúde humana e ambiental
(Thesis) Arguer
Rodrigo Daniel Martins Cordeiro (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/12/15 Materiais em contacto com a água para consumo humano: implementação e validação de um método de ensaio para análise de aminas e nitrosaminas
(Thesis) Arguer
Beatriz Pinto Antunes (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/11/24 Identification of polymethoxylated flavonoids from dried Citrus limon peels
(Thesis) Main arguer
Helena Maria Cordeiro Pires (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/11/21 Extraction and purification of high-value extracts and compounds isolated from Cannabis
(Thesis) Main arguer
Rita Falcão (Other)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2023/11/20 Substances most commonly used to improve work performance, and possible health risks
(Thesis) Main arguer
Joana Filipa Adriano (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/10/20 New class of protein kinase C modulators: from ethnopharmacological to nanoparticles
(Thesis) Main arguer
Vera Mónica Sousa Isca (PhD)
Universidade de Lisboa, Portugal
2023/06/20 Psoriase: manifestações clínicas e opções terapêuticas
(Thesis) Main arguer
Marta Palma Rodrigues (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/05/05 Azeite, compostos fenólicos e alegação de saúde: os azeites nacionais
(Thesis) Arguer
Miriam Sofia da Silva Dourado (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/04/29 isolation and design of diterpenoids from Plectranthus species
(Thesis) Arguer
EPOLE NGOLLE NTUNGWE (PhD)
Universidad de Alcalá, Spain
2023/03/15 Otimização das condições de análise de pesticidas por SPE-HPLC-UV em águas de consumo humano
(Thesis) Arguer
Daniela Filipa de Matos Bernardes (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/02/06 Novel targeted triazene derivatives against metastatic melanoma
(Thesis) Arguer
Keisly Coromoto Da Costa Peña (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/12/13 Development of functional food gel formulations supplemented with the microalgae Arthrospira platensis
(Thesis) Arguer
Daniela Filipa de Matos Bernardes (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/12/13 Formulation and characterization of Locust Bean Gum-based Energy Hydrogels supplemented with Chlorella vulgaris
(Thesis) Arguer
Joana Gonçalves de Almeida (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/11/11 Computer-Assisted Design and Synthesis of DNA-G4:Helicase Interaction Inhibitors
(Thesis) Arguer
Bárbara Bruni (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/09/22 Importância Clínica da Vitamina D
(Thesis) Main arguer
Maryna Danylyuk (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/07/14 Skin Delivery Of Bioactive Plant Extracts Through Nanocarriers
(Thesis) Arguer
Ana Luísa Vargas Henriques Mota (PhD)
Universidade de Lisboa, Portugal
2021/01/28 Perfil Metabólico de Catinonas Sintéticas in vitro: Identificação de metabolitos de Fase I por Espectrometria de Massa de Alta Resolução
(Thesis) Main arguer
Ana Margarida Alves Figueira (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/11/26 Análise Microbiológica da água: técnica de PCR
(Thesis) Arguer
Carolina de Lemos Coelho (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/11/23 Determination of Lead levels in lettuces harvested in different urban environments
(Thesis) Arguer
Joana Raquel Vieira Salvado (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/06/23 Bioactive terpenoids from Euphorbia pubescens: isolation and derivatization
Supervisor
João Paulo Carréu (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/12/20 Antibacterial activity of the chemical constituents of the african medicinal plant Grewia hexamita against resistant bacteria
Supervisor
Sara Filipa Santos Jogo (Master)
2019/12/03 Teor de Açúcares em Néctares de Fruta e Impacto na Saúde do Consumidor
(Thesis) Arguer
Tânia Luísa Pereira Marques Simões (Master)
2019/11/29 Implementação e validação de um método cromatográfico para a determinação de octilfenóis e octilfenóis etoxilados (OF/OFEs) em águas residuais
(Thesis) Arguer
Bárbara Rita Dias Pereira (Master)
2019/05/20 Composição nutricional e bioactividade de frutas e hortícolas: estudo de sumos detox
(Thesis) Arguer
Maria Inês Leitão de Carvalho Santos (Master)
2017/12/22 Development of a small library of bioactive compounds through isolation and molecular derivatization
Supervisor
João Nuno da Silva Gomes (Master)
2017/12/22 Compostos com actividade antitumoral da planta africana Momordica balsamina L.
(Thesis) Arguer
Cristina Isabel Duarte Silva (Master)
2017/12/19 Compostos fenólicos em leguminosas: caracterização da fracção livre e ligada
(Thesis) Arguer
Catarina Isabel Madeira da Conceição Nunes Cardoso (Master)
2017/12/14 Amido resistente e compostos voláteis em diferentes variedades de feijão. Desenvolvimento de uma bolacha à base de farinha de feijão
(Thesis) Arguer
Verónica Silva Gomes (Master)
2017/12/13 Implementação e validação do método TODA-AAS para a monitorização do mercúrio em lamas de ETA e de ETAR
(Thesis) Arguer
Salomé da Visitação Velho Fletcher (Master)
2017/10/25 Reversing multidrug resistance (MDR) in cancer cells by targeting p-glycoprotein (P-gp) : insights into the mechanism of MDR reversal from in silico P-gp modeling
(Thesis) Arguer
Ricardo José Diogo Grácio Ferreira (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/01/11 Caracterização química e avaliação das propriedades biológicas de resíduos provenientes da indústria da cortiça
(Thesis) Main arguer
Rui Filipe da Silva Lúcio Gomes (Master)
2016/11/08 Unravelling new ethnopharmacological roles of Plectranthus species: biological activity screening
(Thesis) Arguer
Joana Eulália da Cruz Marçalo de Andrade (Master)
2016/01/29 Avaliação da actividade antimicrobiana de metabolitos secundários isolados a partir de uma planta usada na medicina tradicional africana
(Thesis) Arguer
Shirley Arnie dos Reis Sancha (Master)
2015/11/23 Terpenoids as effective compounds for overcomimg multidrug resistance in cancer cells
(Thesis) Arguer
Mariana Alves Reis (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015/07/06 Identificação e caracterização por espectrometria de massa com ionizaçãopor eletrospray de antimaláricos que actuam na cadeia mitocondrial de transporte de electrões
(Thesis) Arguer
Ana Raquel Sitoé (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014/05/21 Actividade antibacteriana dos constituintes químicos da planta medicinal africana Cleistochlamys kirkii
(Thesis) Arguer
Ângelo Filipe Almeida Monteiro (Master)
2014/02/03 Anticancer properties of terpenois in resistant cancer cells
Supervisor
Sara Cristina dos Santos Neto (Master)
2012/06/11 Compostos bioativos de Opuntia ficus indica
(Thesis) Arguer
Ana Catarina Jorge Semedo (Master)
2012/03/14 Compostos bioativos isolados de Euphorbia boetica – Modulação da glicoproteína-P
Supervisor
Cátia Vicente Vieira (Master)
2010/09/27 Search for bioactive compounds from medicinal plants used as antimalarials. The study of Momordica balsamina L.
(Thesis) Arguer
Cátia Beatriz Almeida Ramalhete (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Consulting

Activity description Institution / Organization
2018/01 - Current As a member of the Pool of External Experts for EQAVET verification, the National Agency for Qualification and Professional Education has carried out several audits/verification visits compliance within the scope of the European Quality Assurance Reference Framework for Vocational Education and Training, to the Vocational Education Schools. The consultancy service consiste of an auditory and verification visit (1 day) and the preparation of reports for preliminary and final EQAVET verification.

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019 - Current Produtos Naturais na Descoberta de Fármacos Mestradoe em Química Medicinal e Biofarmacêutica Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - Current Métodos de Elucidação Estrutural de Pequenas Moléculas Mestrado em Química Medicinal e Biofarmacêutica (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2009 - Current Metodologias Analíticas Mestrado em Análises Clínicas (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2008 - Current Métodos Instrumentais de Análise Mestrado Integrado em Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2023 - 2024 Espetrometria de massa: aplicações nas ciências farmacêuticas Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/12/16 - 2023/12/16 SHORT COURSE - Exploring drug metabolism: the role of LC-MS/MS analysis (Outros) Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/12/13 - 2023/12/13 Spectroscopic tools for nanomedicines characterization (on PhD Advanced course - Translating nanomedicines: principles of nanomedicines R&D) (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/07/03 - 2023/07/06 Curso de Verão: cromatografia: da teoria à prática (Outros) Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/04/18 - 2022/04/22 PhD Advanced Course (Programa de Doutoramento em Farmácia)- Advanced Analytical Tools: Multiple Applications for Mass Spectrometry - 2nd Edition (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 - 2021 Bromatologia e Tecnologia dos Alimentos Mestrado Integrado em Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 - 2021 Química dos Alimentos Ciências da Nutrição (Licenciatura) Universidade de Lisboa Faculdade de Medicina, Portugal
2020/06/29 - 2020/07/03 PhD Advanced Course (Programa de Doutoramento em Farmácia) - Advanced Analytical Tools: Multiple Applications for Mass Spectrometry (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - 2019 Pós-Graduação em Canábis Medicinal: parceria entre Observatório Português de Canábis Medicinal (OPCM) (Pós-Graduação)
2019 - 2019 Curso de Verão UL: Hands-On: MS - Espectrometria de massa (Outros) Universidade de Lisboa Faculdade de Farmácia, Portugal
2008 - 2019 Produtos Naturais Mestrado em Quimica Farmacêutica e Terapêutica (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2016 - 2016 I Curso de Espectrometria de Massa: Análise de Pequenas Moléculas (Outros) Universidade de Lisboa Faculdade de Farmácia, Portugal
2005 - 2008 Hidrologia e Análises Hidrológicas Ciências Farmacêuticas (Licenciatura) Universidade de Lisboa Faculdade de Farmácia, Portugal
2006 - 2007 Laboratório de Química Analítica Instrumental Ciências Farmacêuticas (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2001 - 2006 Bromatologia e Análises Bromatológicas Ciências Farmacêuticas (Licenciatura) Universidade de Lisboa Faculdade de Farmácia, Portugal
1999 - 2002 Química Analítica Ciências Farmacêuticas (Licenciatura) Universidade de Lisboa Faculdade de Farmácia, Portugal
1997 - 1998 Fundamentos de Química Ciências Farmacêuticas (Licenciatura) Universidade de Lisboa Faculdade de Farmácia, Portugal
1997 - 1998 Química-Física Ciências Farmacêuticas (Licenciatura) Universidade de Lisboa Faculdade de Farmácia, Portugal
1997 - 1998 Física Ciências Farmacêuticas (Licenciatura) Universidade de Lisboa Faculdade de Farmácia, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2023 - Current Foods MDPI
2022 - Current Pharmaceutics MDPI
2021 - Current Frontiers in Pharmacology Frontiers
2021 - Current Pharmaceuticals MDPI
Distinctions

Award

2022 Best oral communication
Sociedade Portuguesa de Química, Portugal
2021 Best oral communication
Sociedade Portuguesa de Química, Portugal
2021 Best poster communication
Universidade da Madeira, Portugal
2014 Best poster communication
Universidade do Minho, Portugal
2005 Best poster communication
Universidade da Madeira, Portugal