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I am a Superior Technician in the Genetics Department of FMUP (Faculty of Medicine of the University of Porto) and, currently, I am in the final stages of completing my PhD in Biomedicine at FMUP as well. My doctoral research takes place in the Genetics Department of FMUP and studies genetic causes of idiopathic pregnancy losses. I am graduated in Genetics and Biotechnology (2012-2015), and concluded an MSc degree in Biotechnology for Health Sciences (2016-2019) from the University of Trás-os-Montes e Alto Douro.
Identification

Personal identification

Full name
Sara Virgínia Fernandes Sampaio de Vasconcelos

Citation names

  • Vasconcelos, Sara

Author identifiers

Ciência ID
0B1B-1702-95B2
ORCID iD
0000-0002-6479-4132

Email addresses

  • svasconcelos@med.up.pt (Professional)

Telephones

Telephone
  • 225513647 (Professional)

Addresses

  • Genetics Department, Faculty of Medicine, University of Porto (FMUP), Alameda Prof Hernâni Monteiro, 4200-319, Porto, Porto, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Genetics and Heredity
  • Medical and Health Sciences - Basic Medicine - Human Genetics
  • Natural sciences - Biological Sciences - Reproductive Biology
  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Spanish; Castilian Upper intermediate (B2) Advanced (C1) Upper intermediate (B2) Advanced (C1)
Education
Degree Classification
2019/10/01 - 2024/09/30
Ongoing
 Biomedicina (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
"Transcriptome and epigenetic analysis of placental and fetal samples from idiopathic pregnancy losses" (THESIS/DISSERTATION)
2016/09 - 2019/02
Concluded
 Biotecnologia para as Ciências da Saúde (Mestrado)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
"Alterações epigenéticas no abortamento espontâneo" (THESIS/DISSERTATION)
 19
2018/09/18 - 2018/12/11
Concluded
 Curso Avançado em Genética Humana Laboratorial (Título de especialista)
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2018/02/19 - 2018/02/23
Concluded
 Curso teórico-prático em Citogenética e Genómica no Diagnóstico e Investigação (Outros)
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal
2012/09 - 2015/07
Concluded
 Genética e Biotecnologia (Licenciatura)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
"Estudo da expressão de VEGF-A e Cox-2 em lesões hiperplásicas e tumorais da próstata de cão" (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2025 - Current Researcher (Research) RISE - Health Research Network, Portugal
2017/09 - Current Researcher (Research) Universidade do Porto Faculdade de Medicina, Portugal
2019 - 2024 Researcher (Research) i3S - Instituto de Investigação e Inovação em Saúde, Portugal
i3S - Instituto de Investigação e Inovação em Saúde, Portugal
2015/10 - 2016/04 Research Trainee (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/02 - 2015/06 Research Trainee (Research) Universidade de Trás-os-Montes e Alto Douro, Portugal
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências Agrárias e Veterinárias, Portugal
2014/06 - 2014/08 Research Trainee (Research) Institut de Recerca Biomèdica, Spain

Other Careers

Category
Host institution 		Employer
2023/12 - Current Técnico Superior (Técnico Superior) Universidade do Porto Faculdade de Medicina, Portugal
Projects

Grant

Designation Funders
2021 - Current The role of (epi)genetic mechanisms in oocyte maturation and idiopathic pregnancy losses - new insigts into human reproduction
EXPL/MED-GEN/1261/2021
PhD Student Fellow
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2019/06/01 - 2019/09/30 Epigenetic and transcriptional analysis of TSC2 in leukocyte DNA from tuberous sclerosis patients
6544333
Research Fellow
Universidade do Porto Faculdade de Medicina, Portugal
Concluded

Other

Designation Funders
2023 - Current The effects of cryopreservation on the epigenome of human sperm.
2022. 09829.PTDC
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Conference poster
  1. "Xp22.31 microduplications involving STS, VCX and PUDP genes". Paper presented in European Cytogeneticists Association, 2021.
  2. "EXPRESSION ANALYSIS OF EPIGENETIC REGULATORS IN HUMAN PLACENTAS FROM IDIOPATHIC PREGNANCY LOSSES". Paper presented in 25th Annual Meeting of the Portuguese Society of Human Genetics (SPGH Sociedade Portuguesa de Genética Humana), 2021.
  3. "SKEWED X-CHROMOSOME INACTIVATION IN RECURRENT PREGNANCY LOSS". Paper presented in 25th Annual Meeting of the Portuguese Society of Human Genetics (SPGH Sociedade Portuguesa de Genética Humana), 2021.
  4. Vasconcelos, Sara; Capela, Liliana; Marques, C.J.; Fernandes, Susana; Grangeia, Ana; Leão, Miguel. "Epigenetic and transcriptional analysis of TSC2 in Tuberous Sclerosis patients". Paper presented in 24th Annual Meeting of the Portuguese Society of Human Genetics (SPGH – Sociedade Portuguesa de Genética Humana), 2020.
  5. Vasconcelos, Sara; Ramalho, Carla. "Dysregulation of imprinted genes and epigenetic modifiers in human placental and fetal tissues from second trimester pregnancy losses". Paper presented in Genomic Imprinting - from Biology to Disease, 2020.
  6. Vasconcelos, Sara; Caniçais, Carla; Ramalho, Carla; Marques, C.J.; Doria, Sofia. "Altered expression of imprinted genes expression and epigenetic regulators in intrauterine growth restriction placental tissue". Paper presented in Genomic Imprinting – from Biology to Disease, 2020.
  7. Vasconcelos, Sara; Ramalho, Carla; Marques, C. J.; Doria, Sofia. "Epigenetic modifications could contribute for second trimester pregnancy spontaneous losses". Paper presented in 22th Annual Meeting of the Portuguese Society of Human Genetics (SPGH – Sociedade Portuguesa de Genética Humana), 2018.
Journal article
  1. Caniçais, Carla; Sobral, Daniel; Vasconcelos, Sara; Cunha, Mariana; Pinto, Alice; Mesquita Guimarães, Joana; Santos, Fátima; et al. "Transcriptomic analysis and epigenetic regulators in human oocytes at different stages of oocyte meiotic maturation". Developmental Biology 519 (2025): 55-64. https://doi.org/10.1016/j.ydbio.2024.12.004.
    10.1016/j.ydbio.2024.12.004
  2. Vaz, Diane; Vasconcelos, Sara; Caniçais, Carla; Costa, Beatriz; Ramalho, Carla; Marques, Joana; Dória, Sofia. "X-chromosome inactivation pattern and telomere length in recurrent pregnancy loss". Reproductive Biology 24 4 (2024): 100933. https://doi.org/10.1016/j.repbio.2024.100933.
    10.1016/j.repbio.2024.100933
  3. Sara Vasconcelos; Ioannis Moustakas; Miguel R. Branco; Susana Guimarães; Carla Caniçais; Talia van der Helm; Carla Ramalho; et al. "Syncytiotrophoblast Markers Are Downregulated in Placentas from Idiopathic Stillbirths". International Journal of Molecular Sciences (2024): https://doi.org/10.3390/ijms25105180.
    10.3390/ijms25105180
  4. Vasconcelos, Sara; Caniçais, Carla; Susana M. Chuva de Sousa Lopes; C. Joana Marques; Professora Doutora Sofia Dória Príncipe dos Santos Cerveira. "The role of DNA hydroxymethylation and TET enzymes in placental development and pregnancy outcome.". Clinical Epigenetics 25 15 (2023):
    Open access • Published
  5. Ana Jalles; Cármen Vieira; Joana Pereira-Sousa; Daniela Vilas Boas da Silva Campos; Ana Francisca Mota; Sara Vasconcelos; Bruna Ferreira-Lomba; et al. "Aripiprazole Offsets Mutant ATXN3-Induced Motor Dysfunction by Targeting Dopamine D2 and Serotonin 1A and 2A Receptors in C. elegans". Biomedicines (2022): https://www.mdpi.com/2227-9059/10/2/370.
    10.3390/biomedicines10020370
  6. Caniçais, Carla; Vasconcelos, Sara; Ramalho, Carla; Marques, C.J.; Doria, Sofia. "Deregulation of imprinted genes expression and epigenetic regulators in placental tissue from intrauterine growth restriction". Journal of Assisted Reproduction and Genetics (2021): DOI: 10.1007/s10815-020-02047-3.
    Published
  7. Vasconcelos, Sara; Ramalho, Carla; Marques, C. Joana; Doria, Sofia. "Altered expression of epigenetic regulators and imprinted genes in human placenta and fetal tissues from second trimester spontaneous pregnancy losses". Epigenetics 14 12 (2019): 1234-1244. http://dx.doi.org/10.1080/15592294.2019.1634988.
    Published • 10.1080/15592294.2019.1634988
Thesis / Dissertation
  1. Vasconcelos, Sara. "Alterações epigenéticas no abortamento espontâneo". Master, Universidade do Porto Faculdade de Medicina, 2019.