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Catarina Custódio holds a BSc degree in Applied Chemistry from Faculty of Science and Technology of New University of Lisbon and a Doctoral Degree in Tissue Engineering, Regenerative Medicine and Stem Cells from University of Minho in a collaboration with the Max Planck Institute for Polymer Research in Germany (2013). In 2014 she was awarded with a FCT Post-doctoral grant to develop a project on the patterning of chitosan hydrogels towards controlling cellular function to enhance endogenous cardiac repair. Currently, she is an Assistant Researcher (CEEC) and Principal Investigator of a national R&D project at CICECO-Aveiro Institute of Materials, University of Aveiro. Her main scientific interests are on novel biomaterials for Tissue Engineering and Regenerative Medicine. Her research has a strong translational focus with the main goal of manipulating microenvironments that cells interact with, to facilitate cell assembly and build functional tissue for customized therapies with a particular attention on cardiovascular disease. So far, she has published more than 50 peer-reviewed papers in high impact international journals, summing more than 1800 citations and an h-index 25 (Scopus at 04/2025). She has been actively involved in writing competitive international and national funding proposals and and has been an ad-hoc reviewer for top-quality international journals. Part of her work is focused in product development and translational research to engineer innovative 3D platforms for cell culture. She is a co-founder of the startup Metatissue (2018). The core competency of the company lies in the design and development of novel soft materials for 3D cell culture.
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Identification

Personal identification

Full name
Catarina Custódio

Citation names

  • Custódio, Catarina A.

Author identifiers

Ciência ID
0A10-D092-BD3C
ORCID iD
0000-0003-2967-700X
Google Scholar ID
https://scholar.google.com/citations?user=05NgwUQAAAAJ&hl=pt-PT&oi=ao
Scopus Author Id
26643851500

Email addresses

  • catarinacustodio@ua.pt (Professional)

Addresses

  • Department of Chemistry, CICECO - Aveiro Institute of Materials, University of Aveiro. Department of Chemistry, CICECO - Aveiro Institute of Materials University of Aveiro, 3810-193 Aveiro, Portugal, 3810-193, Aveiro, Aveiro, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology
  • Engineering and Technology - Medical Engineering
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
  • Engineering and Technology - Industrial Biotechnology - Bio-derived Novel Materials
  • Medical and Health Sciences - Medical Biotechnology - Biomaterials
  • Medical and Health Sciences - Clinical Medicine - Cardiac and Cardiovascular Systems
  • Exact Sciences - Chemical Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Advanced (C1) Intermediate (B1) Intermediate (B1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1)
German Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Portuguese (Mother tongue)
Education
Degree Classification
2025/11 - 2025/11
Concluded
 Management Acceleration Program (Outros)
NOVA University Lisbon NOVA SBE Venture Lab, Portugal
2013
Concluded
 Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento)
Universidade do Minho Escola de Engenharia, Portugal
"Immobilization of biomolecules into biodegradable polymeric based substrates for selective recruitment and adhesion of cells for tissue engineering applications" (THESIS/DISSERTATION)
 Aprovado
2007
Concluded
 Química Aplicada (Licenciatura)
Major in Biotecnologia
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Optimization of the conditions for overexpression of metallothionein in the K-562 cell line" (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution		 Employer
2021/04/01 - Current Auxiliary Researcher (Research) Universidade de Aveiro CICECO, Portugal
Universidade de Aveiro Departamento de Química, Portugal
(...)
2018/04 - 2021/03/31 Contracted Researcher (Research) Universidade de Aveiro Departamento de Química, Portugal
Universidade de Aveiro Departamento de Química, Portugal
(...)
2016/04/04 - 2018/06/14 Postdoc (Research) Universidade de Aveiro, Portugal
Universidade de Aveiro CICECO, Portugal
(...)
2014/02/01 - 2016/03/31 Postdoc (Research) Universidade do Minho Departamento de Engenharia de Polímeros, Portugal
Laboratório Associado ICVS 3B's, Portugal
2007/11/01 - 2009/09/30 Researcher (Research) Universidade do Minho Departamento de Engenharia de Polímeros, Portugal
Laboratório Associado ICVS 3B's, Portugal
2006/02/01 - 2006/07/30 Research Trainee (Research) Katholieke Universiteit Leuven, Belgium
Katholieke Universiteit Leuven Faculteit Wetenschappen, Belgium

Positions / Appointments

Category
Host institution		 Employer
2018/04/04 - Current CEO and Co-founder METATISSUE, Portugal
METATISSUE, Portugal

Others

Category
Host institution		 Employer
2009/10/01 - 2013/10/01 Ph.D. in Tissue Engineering, Regenerative Medicine and Stem Cells, Ph.D. thesis title: Immobilization of biomolecules into biodegradable polymeric based substrates for selective recruitment and adhesi Universidade do Minho Departamento de Engenharia de Polímeros, Portugal
Laboratório Associado ICVS 3B's, Portugal
2010/10/18 - 2011/09/05 Visiting PhD student- Development of photosensitive chitosan surfaces for controlled cell attachment Max-Planck-Institut für Polymerforschung, Germany
Max-Planck-Institut für Polymerforschung, Germany
2005/09/01 - 2006/02/01 Trainee- Under supervision of Dr. Alice Pereira Universidade Nova de Lisboa Departamento de Química, Portugal
Universidade Nova de Lisboa Departamento de Química, Portugal
Projects

Grant

Designation Funders
2020/09 - Current AMNIOGEL - Extracellular matrix derived products from human placenta to engineer bone microtissues for in vitro disease models
957585
Supervisor
Universidade de Aveiro CICECO, Portugal
 European Research Council
2019 - Current HYDROMAN - A new platform for developing 3D humanized in vitro osteosarcoma models for drug screening and validation: Hydrogels based on human platelet lysates
HYDROMAN
Researcher
Institut Jean Lamour, France
Ongoing
2025/07/01 - 2028/06/30 Revolucionando Modelos de Doenças e Triagem de Medicamentos com um Sistema Microfisiológico Cardíaco Totalmente Humano Impresso em 3D.
COMPETE2030-FEDER-00836800
Principal investigator
Universidade de Aveiro, Portugal

Universidade de Aveiro CICECO, Portugal
Ongoing
2023/03/01 - 2028/03/31 3D Printing of Ultra-fideLity tissues using Space for anti-ageing solutions on Earth
101099346
Supervisor
2023/05 - 2027/10 BioRobot-MiniHeart- Building a human mini-heart in the lab
101070953
Co-Principal Investigator (Co-PI)
METATISSUE, Portugal
Ongoing
2023/05 - 2027/05 GUT MICROBIOTA-INDUCED TREGS FOR INFLAMMATORY BOWEL DISEASE (IBD) IMMUNOTHERAPY (MITI2)
101080445
Co-Principal Investigator (Co-PI)
Ongoing
2023/01/01 - 2026/12/31 TheraTools - Innovative tools to treat and model complex cancer environments
Grant agreement ID: 101073404
Supervisor
Universidade de Aveiro, Portugal
Ongoing
2021/11/01 - 2026/10/31 REBORN - Full human-based multi-scale constructs with jammed regenerative pockets for bone engineering
883370
Supervisor
Universidade de Aveiro CICECO, Portugal

Universidade de Aveiro Departamento de Química, Portugal
Ongoing
2021/09/01 - 2025/08/31 UroPrint-Urinary bladder bioprinting for fully autologous transplantation
964883
Principal investigator
METATISSUE, Portugal
 EU Framework Programme for Research and Innovation Future and Emerging Technologies
Ongoing
2021/01/01 - 2025/01/31 InterLynk - Human Platelet Lysates-based Scaffolds for Interfacial Multi-tissue Repair
953169
Principal investigator
Horizon 2020

EU Framework Programme for Research and Innovation Industrial Leadership
Ongoing
2021/03 - 2024/03 Tetrissue- Bioinspired tile-matching to create ultrastructured bone microtissues in a close-to-native fashion
PTDC/BTM-MAT/3201/2020
Researcher
Universidade de Aveiro CICECO, Portugal

Universidade de Aveiro Departamento de Química, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/03 - 2024/03 Tetrissue- Bioinspired tile-matching to create ultrastructured bone microtissues in a close-to-native fashion
PTDC/BTM-MAT/3201/2020
 Fundação para a Ciência e a Tecnologia
2022/06/01 - 2023/05/31 TechTissue - Validate human-based 3D in vitro models for accurate drug discovery and development towards a successful market entry
101072131
Principal investigator
METATISSUE, Portugal
Ongoing
2013/01 - 2015/03 Multilayered and hierarchically polymeric particles production for bone tissue engineering using a new biomimetic platform inspired on natural repellent substrates
Provided by PTCRIS: 127180
Research Fellow
Fundação para a Ciência e a Tecnologia, I.P.

Contract

Designation Funders
2019/07/01 - Current Une nouvelle plateforme pour développer des modèles d'ostéosarcome in vitro 3D humanisés pour le criblage et la validation de médicaments : Des Hydrogels à base de lysats plaquettaires humains (HYDROMAN)
HYDROMAN
Institut Jean Lamour, France
 Cancéropôle du Grand Ouest
Ongoing
2018/07/26 - 2021/07/25 Efficient methodologies for the conjugation of natural polysaccharides with peptides to obtain multifunctional membranes for periodontal regeneration.
PTDC/QUI-QOR/30771/2017
PTDC/QUI-QOR/30771/2017
Researcher
Universidade de Aveiro CICECO, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/22 - 2021/07/21 Directing Bone Dynamics Through The Synergistic Action Of Immune Cells With Bioengineered Cell Microfactories Containing Patterned Microplatforms
PTDC/BTM-MAT/31064/2017
Researcher
Universidade de Aveiro CICECO, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/20 - 2021/07/19 High performance multicompartmental spherical capsules for transplantation of multimodal co-cultures of adipose-derived stem cells and pancreatic islets
PTDC/BTM-ORG/30770/2017
PTDC/BTM-ORG/30770/2017
Researcher
Universidade de Aveiro CICECO, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/07 - 2021/07 PANGEIA- Microencapsulated 3D+ Cancer-Stroma Microtumor-based In vitro Testing Platforms for High-Throughput Screening of Combinatorial Therapies for Pancreatic Cancer
PTDC/BTM-SAL/30503/2017
PTDC/BTM-SAL/30503/2017
Researcher
Universidade de Aveiro CICECO, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/06/26 - 2021/06/25 PROMENADE - 3D cells colonization in marine-derived hydrogels through controlled micro-channels patterning for bone repair
PTDC/BTM-MAT/29830/2017
Researcher
Universidade de Aveiro CICECO, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/06/22 - 2021/06/21 BEAT- Platelet Lysate Hydrogels for Myocardial Repair
PTDC/BTM-MAT/30869/2017
Principal investigator
Universidade de Aveiro CICECO, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/06/22 - 2021/06/21 DNA Base Pairing-based Supramolecular Self-Sorting Devices: A Molecular Recognition and Biomimetic Technology to Screen Target Cells for Biomedical and Healthcare Applications
PTDC/QUI-OUT/30658/2017
Researcher
Universidade de Aveiro CICECO, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2015/12 - 2020/11 ATLAS - Bioengineered autonomous cell-biomaterials devices for generating humanised micro-tissues for regenerative medicine
669858
Researcher
Universidade de Aveiro CICECO, Portugal
 European Research Council
Ongoing
2019/01/01 - 2019/12/31 CICECO-Instituto de Materiais de Aveiro
UID/CTM/50011/2019
LA/P/0006/2020
10.54499/LA/P/0006/2020
Universidade de Aveiro, Portugal

Universidade de Aveiro CICECO, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2018/03/01 - 2019/08/31 MICROBONE: Novel 3D platforms to engineer bone microtissues for in vitro disease models
info:eu-repo/grantAgreement/EC/H2020/789760/EU
Researcher
Universidade de Aveiro CICECO, Portugal
 European Commission
Concluded
2013/05 - 2018/04 ComplexiTE - An integrated multidisciplinary tissue engineering approach combining novel high-throughput screening and advanced methodologies to create complex biomaterials-stem cells constructs
321266
Post-doc Fellow
Laboratório Associado ICVS 3B's, Portugal
 European Research Council
Concluded
2016/06/01 - 2016/06/01 3D Bioencapsulated hydrogel(s) Constructs for Organ Printing: From Concept to Reality
PTDC/BBB-ECT/3213/2014
Researcher
Laboratório Associado ICVS 3B's, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2014/03 - 2015/06 BioSeaGlue - Multifunctional layer-by-layer coatings inspired by mussels that combine bioactivity with superior adhesion for orthopaedic applications
Provided by PTCRIS: 133668
Researcher
Fundação para a Ciência e a Tecnologia, I.P.
2012 - 2015 Matryoshkas - Multilayered and hierarchically polymeric particles production for bone tissue engineering using a new biomimetic platform inspired on natural repellent substrates.
PTDC/CTM-BIO/1814/2012
Research Fellow
Laboratório Associado ICVS 3B's, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2007/09/03 - 2010/03/31 PHOTONANOTECH - Photozyme Nanoparticle applications for water purification, textile finishing, photodynamic biomineralization and biomaterial coating
Research Fellow
Laboratório Associado ICVS 3B's, Portugal
 European Research Council
Concluded
Outputs

Publications

Book
  1. Custódio, Catarina A.; Deus, Inês; Monteiro, Cátia F.; Santos, Sara C.; Mano, J.F.. Soft Matter for Biomedical Applications. Royal Society of Chemistry. 2021.
    Accepted
  2. Custódio, Catarina; Reis, R.L.; Mano, J.F.; Del Campo, A.. Smart Polymers and their Applications: Chapter 12 - Smart Instructive Polymer Substrates for Tissue Engineering. Elsevier. 2019.
    Published • 10.1016/c2013-0-16347-7
  3. Custódio, Catarina A.; Reis, R.L.; Mano, J.F.; Del Campo, A.. Smart instructive polymer substrates for tissue engineering. 2014.
    Published • 10.1533/9780857097026.2.301
Book chapter
  1. Deus, Inês A.; Santos, Sara C.; Monteiro, Cátia F.; Gomes, M. C. ; Custódio, Catarina A.; Mano, Joao F.. "Human protein-based soft materials for tissue engineering applications". In Soft Matter for Biomedical Applications. 2021.
    Accepted
  2. Custódio, Catarina A.; Santos, Sara C.; Monteiro, Cátia F.; Deus, Inês A.; Gomes, Maria C.; Mano, Joao F.. "Chapter 26: Animal Protein-based Soft Materials for Tissue Engineering Applications". In Animal Protein-based Soft Materials for Tissue Engineering Applications, 660-683. The Royal Society of Chemistry, 2021.
    10.1039/9781839161124-00660
Conference abstract
  1. Ladeira, Bruno; Maria C. Gomes; Custódio, Catarina A.; Mano, Joao F.. "Biofabrication of injectable granular matrices for cell delivery through the supramolecular assembly of decellularized human tissue". Paper presented in TERMIS European Congress 2025, Freiburg, 2025.
  2. Rufino, A.T.; Dias, Mariana; Mano, Joao F.; Custódio, Catarina A.. "Advancing 3D Cell Culture and Organ-on-Chip Models: hPLMA as a Superior, Biocompatible Alternative to Matrigel with Reduced Immunogenicity and Enhanced Stability". Paper presented in Tissue Engineering and Regenerative Medicine Society (TERMIS) European Congress 2025, Freiburg, 2025.
Conference paper
  1. Bruno M. Ladeira; Maria C. Gomes; Custódio, Catarina A.; Mano, Joao F.. "Recreating the dynamic properties of the ECM through cyclodextrin-mediated assembly of human amniotic membrane". Paper presented in Jornadas do CICECO 2023, Aveiro, 2023.
  2. Bruno M. Ladeira; Maria C. Gomes; Custódio, Catarina A.; Kongchang Wei; Mano, Joao F.. "Leveraging host-guest interactions to produce highly reshapable soft hydrogels from proteins of human origin". Paper presented in 33rd Annual Conference of the European Society for Biomaterials, ESB2023, Davos, 2023.
  3. "A human-based 3D platform to support osteosarcoma spheroid invasion in a tri-culture environment for disease modelling and drug screening applications". Paper presented in 6th TERMIS World Congress, 2021.
    Published
  4. Silva, Joana M.; Custódio, Catarina A.; Reis, R. L.; Mano, J. F.. "Multilayered Hollow Tubes for Cardiovascular Tissue Engineering". Paper presented in 4th TERMIS World Congress, 2015.
    Published
  5. Custódio, Catarina A.; Gasperini L.,; Reis, Rui L.; Mano, João F.. "Cell Type Specific Microspheres Incorporating Growth Factors as Injectable Cell Carriers for Tissue Repair". Paper presented in 4th TERMIS World Congress, 2015.
    Published
  6. Custódio, Catarina A.; Cerqueira, M. T.; Marques, A. P.; Reis, R. L.. "Functional chitosan microcarriers for selective cell attachment and expansion". Paper presented in TERM STEM, 2014.
    Published
  7. Custódio, Catarina A.; Silva, Joana M.; Duarte, Ana R.; Sher Praveen; Neto, Ana I.; Pinho, António; Fonseca, Jaime; Reis, Rui L.; Mano, João F.. "Nanostructured Hollow tubes based on chitosan and alginate multilayers". Paper presented in TERM STEM 2013, 2013.
    Published
  8. Neto, A. I.; Correia, C.R.; Custódio, Catarina A.; Mano, João F.. "Miniaturized droplets-based microarray of chemical and biological high-throughput tests". Paper presented in TERM STEM, 2013.
    Published
  9. Costa, R. R.; Castro-Otero E.; Custódio, Catarina A.; Testera, A.M.; Arias, F.J.; Rodríguez-Cabello, J.C.; Mano, João F.. "Extrapolation of hybrid polysaccharide and recombinant polypeptide multilayer films towards three-dimensional compartmentalization". Paper presented in TERM STEM, 2013.
    Published
  10. Custódio, Catarina A. (0A10-D092-BD3C); Cerqueira, M. T.; Marques, A. P.; Reis, R. L.; João. F. Mano. "Functional cell microcarriers- a new platform for cell separation and expansion". Paper presented in TERM STEM, 2013.
    Published
  11. Costa, R.R.; Custódio, Catarina A.; Arias, F.J.; Rodríguez-Cabello, J.C.; Mano, J. F.. "Self-Assembled Microcapsules with Tunable and Sustained Release of Macromolecules for Tissue Engineering". Paper presented in TERMIS World Congress 2012, 2012.
    Published
  12. Custódio, Catarina A.; Santo, V.E.; Gomes, M.E.; Reis, Rui L.; Mano, João F.. "Development of bioactive constructs through cell crosslinking for tissue regeneration". Paper presented in TERM STEM, 2012.
    Published
  13. Custódio, Catarina A.; Frias, A.M.; Del Campo, A.; Reis, Rui L.; Mano, João F.. "Chitosan membranes for spatially controlled cell adhesion and specific cell recruitment". Paper presented in 3rd TERMIS World Congress, 2012.
    Published
  14. Custódio, Catarina A.; Lima, Ana C.; Alvarez-Lorenzo, C.; Mano, João F.. "Multilayered polymeric particle production using superhydrophobic surfaces methodology for drug delivery and tissue engineering applications". Paper presented in TERM STEM, 2012.
    Published
  15. Costa Rui R.; Custódio, Catarina A.; Arias, F.J.; Rodríguez-Cabello J. C.; Mano, J.F.. "Nanostructured Films Exhibiting Multiple Stimuli Responsive Behavior and Improved Cell Adhesion for Tissue Engineering". Paper presented in TERMIS-EU 2011, 2011.
    Published
  16. Custódio, Catarina A.; Alves, C. M.; Reis, Rui L.; Joao F. Mano. "Immobilization of Biomolecules on Chitosan Surface for Selective Recruitment, Controlled Growth and Differentiation of Cells from Mixed Populations". Paper presented in TERMIS-EU 2008 Porto Meeting, 2008.
    Published
Conference poster
  1. Ladeira, Bruno; Custódio, Catarina A.; Mano, Joao F.. "Engineering mechanical tunability in human-derived materials by combining covalent and supramolecular interactions". Paper presented in Jornadas CICECO 2025: Navigating the Borders of Knowledge, 2025.
  2. Ladeira, Bruno; Custódio, Catarina A.; Mano, Joao F.. Corresponding author: Ladeira, Bruno. "Combining supramolecular and covalent interactions to achieve mechanical tunability in human dECM-based scaffolds". Paper presented in SupraLife Final International Conference - Supramolecular Multifunctional Biomaterials & Systems for Biomedical and Healthcare Applications, 2025.
  3. LUIZ, MARIA EDUARDA; James P.K. Armstrong; Custódio, Catarina A.; Bakht, Syeda Mahwish; Mano, Joao F.. "Contactless Ultrasound-Induced Cell Alignment for Bioengineered Cardiac Tissue Models". Paper presented in SupraLife Final International Conference, 2025.
  4. Martins, Elisa A.G.; Monteiro, Cátia F.; Luís P. G. Monteiro; Custódio, Catarina A.; Mano, Joao F.. "Guiding Cells Through Directional Freeze Casting of Human Placental Chorionic Membrane". Paper presented in European Society of Biomaterials (ESB) 2025 Congress, 2025.
  5. Costa, Marcelo; Custódio, Catarina A.; Sobreiro-Almeida, Rita; Mano, Joao F.. "Engineering human-based nanocomposite materials to develop complex 3D single and multi-material structures for tissue regeneration". Paper presented in Supralife Final International Conference, 2025.
  6. Monteiro, Cátia F.; Maria Clara Gomes; Bharmoria, Pankaj; Mara G. Freire; Coutinho, Joao A. P.; Custódio, Catarina A.; Mano, Joao F.. "Human protein-based nanofibrils assemble into ultrathin membranes to generate cell-sculpted 3D bone microtissue". Paper presented in CICECO&I3N - Materials Processing and Nanofabrication WORKSHOP, 2025.
  7. Fuentes, Julián; Monteiro, Cátia F.; Beloqui, Ana; Custódio, Catarina A.; Mano, Joao F.. "Human Platelet Lysate-Derived Nanoparticles: A Novel Drug Delivery Platform". Paper presented in SupraLife Third School, 2025.
  8. Costa, Marcelo; H.Middleton; Tiago R. Correia; Custódio, Catarina A.; Sobreiro-Almeida, Rita; Mano, Joao F.. "Engineering tunable hydroxyapatite-human based materials to develop complex 3D structures for multi-tissue regeneration". Paper presented in SupraLife Third School - Supramolecular Multifunctional Biomaterials, 2025.
  9. Monteiro, Cátia F.; Gomes, M. C. ; Pankaj Bharmoria; Mara G. Freire; Coutinho, Joao A. P.; Custódio, Catarina A.; Mano, Joao F.. "Human platelet lysates-derived fibrils as building blocks to produce free-standing membranes for cell self-aggregation". Paper presented in Jornadas do CICECO, 2024.
  10. Bruno M. Ladeira; Maria C. Gomes; Custódio, Catarina A.; Mano, Joao F.. "Harnessing Human Extracellular Matrix to Produce Self-Curing Granular Hydrogels for Cell Delivery". Paper presented in Jornadas do CICECO 2024, 2024.
  11. Deus, Inês A.; Custódio, Catarina A.; Mano, Joao F.. Corresponding author: Deus, Inês A.. "Microphysiological engineering of cardiac fibrotic tissues using human extracellular matrix for disease modelling". Paper presented in Annual EUROoCS Conference 2024, 2024.
  12. Monteiro, Cátia F.; Deus, Inês A.; Silva, Inês B.; Duarte, Iola F; Custódio, Catarina A.; Mano, Joao F.. "Advancing tumor-on-a-chip by integrating a 3D human-based hydrogel to study invasive and metastatic tumor inter-heterogeneity". Paper presented in EUROoCS Annual Meeting, 2024.
  13. Sobreiro-Almeida, Rita; Santos, Sara C.; Correia, Tiago R.; Decarli, Monize; Costa, Marcelo; Babilotte, Joanna; Custódio, Catarina A.; Moroni, Lorenzo; Mano, Joao F.. Corresponding author: Sobreiro-Almeida, Rita. "Blood components as basis to engineer highly bioactive and customized implantable biomaterials with programmable architectures". Paper presented in Bioinspired Materials Gordon Research Conferences, 2024.
  14. Martins, Elisa A.G.(821C-E851-B932); Monteiro, Luís P. G.; Custódio, Catarina A.; Mano, Joao F.. "Bioactive human-based cryogels to fabricate bioinspired scaffolds for bone tissue engineering". Paper presented in SupraLife Second School, 2024.
  15. Bruno M. Ladeira; Maria C. Gomes; Custódio, Catarina A.; Mano, Joao F.. Corresponding author: Bruno M. Ladeira. "Exploiting Cyclodextrin-Protein Interactions to Generate Dynamic Biomaterials from Human Amniotic Membrane". Paper presented in SupraLife Second School, 2024.
  16. Santos, Sara C.; Custódio, Catarina A.; Mano, Joao F.. "Xeno-free cardiac tissue repair enabled by human protein-based microparticles as cell carriers". Paper presented in Jornadas CICECO 2023, 2023.
  17. Monteiro, Cátia F.; Deus, Inês A.; Silva, Inês B.; Duarte, Iola F; Custódio, Catarina A.; Mano, Joao F.. "A tumor-on-a-chip incorporating human-based hydrogels for easy assessment of tumor invasion and metastasis". Paper presented in Jornadas do CICECO, 2023.
  18. Sousa, Joana P.M.; Deus, Inês A.; Monteiro, Cátia F.; Custódio, Catarina A.; Stratakis, Emmanuel; Mano, Joao F.; Marques, Paula A.A.P.. "Amniotic membrane-derived anisotropic hydrogels for neural tissue repair". Paper presented in 33rd Annual Conference of the European Society for Biomaterials, 2023.
  19. Martins, Elisa A.G.; Custódio, Catarina A.; Mano, Joao F.. "Development of bioactive human-based cryogels to fabricate bio-inspired scaffolds for bone tissue engineering". Paper presented in Ciência 2023, 2023.
  20. Monteiro, Cátia F.; Deus, Inês A.; Silva, Inês B.; Duarte, Iola F; Custódio, Catarina A.; Mano, Joao F.. "tumor-on-a-chip incorporating human-based hydrogels for easy assessment of tumor invasion and metastasis". Paper presented in Microphysiological Systems World Summit, 2023.
  21. Bruno M. Ladeira; Maria C. Gomes; Custódio, Catarina A.; Mano, Joao F.. Corresponding author: Bruno M. Ladeira. "Exploring host-guest interactions between cyclodextrins and proteins to produce supramolecular amniotic membrane hydrogels". Paper presented in SupraLife First School “Functional Supramolecular Polymeric Biomaterials”, 2023.
  22. Monteiro, Cátia F.; Custódio, Catarina A.; Mano, Joao F.. "Bioengineering humanized 3D osteosarcoma models for therapy development – moving from static to dynamic modelling". Paper presented in Jornadas do CICECO, 2022.
  23. "Advanced allogeneic porous matrices for personalized cell culture and tissue engineering". Paper presented in 6th TERMIS World Congress, 2021.
  24. "Human platelet lysates-based hydrogels to assess osteosarcoma spheroid invasiveness in a tri-culture model for drug screening applications". Paper presented in 31st Annual Conference of the European Society for Biomaterials (ESB 2021), 2021.
  25. Santos, Sara C.; Custódio, Catarina A.; Mano, Joao F.. "Human-based protein porous scaffolds as platforms for xeno-free 3D cell culture". Paper presented in Jornadas do CICECO 2020, 2020.
  26. Santos, Sara C.; Custódio, Catarina A.; João F. Mano. "Establishment of xenogeneic platforms for 3D cell culture using human protein-based porous scaffolds". Paper presented in Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Meeting 2020 (TERMIS EU 2020), 2020.
  27. Custódio, Catarina A.; Santos, Sara C.; Monteiro, Cátia F.; Deus, Inês A.; Mano, João F.. "Humanized 3D cell culture models - a new era for engineering tissues". Paper presented in World Biomaterials Congress 2020, 2020.
  28. Santos, Sara C.; Custódio, Catarina A.; Mano, João F.. "Human platelet lysates-based sponges: a solution to culture human cells in serum free conditions". Paper presented in 11th World Biomaterials Congress WBC 2020, 2020.
  29. Cátia F. Monteiro; Custódio, Catarina A.; João. F. Mano. "A human-based 3D platform to support osteosarcoma spheroid invasion for disease modelling applications". Paper presented in European Chapter of the Tissue Engineering and Regenerative Medicine International Society, Inc. (TERMIS), Manchester, United Kingdom, 2020.
  30. Custódio, Catarina A.; Cátia F. Monteiro; João. F. Mano. "A platelet lysates-based 3D platform for humanized cancer invasion modelling for preclinical research". Paper presented in EACR-AACR Basic and Translational Research Conference: Tumor Microenvironment, Lisboa, Portugal, 2020.
  31. Tavares, Márcia T.; Santos, Sara C.; Farinha, José Paulo S.; Baleizão, Carlos; Custódio, Catarina A.; Mano, João F.. "Platelet Lysate-based Hydrogels Incorporated with Multi-Bioactive Mesoporous Silica Nanoparticles for Stem Cell Osteogenic Differentiation". Paper presented in Jornadas CICECO 2019, 2019.
  32. Monteiro, Cátia F.; Custódio, Catarina A.; Mano, João F.. "Human platelet lysates-based hydrogels as a 3D platform for spheroid invasion assessment". Paper presented in Jornadas do CICECO, 2019.
  33. Custódio, Catarina A.; Catia F. Monteiro; Joao F. Mano. "Human platelet lysates based hydrogels – a novel personalized 3D platform for spheroid invasion assessment". Paper presented in Jornadas do CICECO, Aveiro, Portugal, 2019.
  34. Custódio, Catarina A.; Santos, Sara C.; João. F. Mano. "Human platelet lysates-based hydrogels: a novel platform for tissue engineering applications". Paper presented in Jornadas do CICECO 2019, 11-12 June 2019, Aveiro, 2019.
  35. Custódio, Catarina A.; Sara C. Santos; Catia F. Monteiro; Joao F. Mano. "Designing humanized hydrogels toward tissue engineering and disease modeling". Paper presented in 13th International Chemical and Biological Engineering Conference (CHEMPOR 2018), Aveiro, Portugal, 2018.
  36. Monteiro, Cátia F.; Custódio, Catarina A.; Mano, João F.. "Human platelet lysate based hydrogels – a novel personalized 3D platform for spheroid invasion assessment". Paper presented in 3rd EACR Conference - Goodbye Flat Biology: In Vivo Inspired Cancer Biology and Therapy, 2018.
  37. Custódio, Catarina A.; Martins, C. M.; Mano, João F.. "Designing multifunctional laminarin microparticles for 3D cell culture". Paper presented in 5th TERMIS World Congress, 2018.
  38. Custódio, Catarina A.; Santos, Sara C.; Mano, João F.. "Customized platelet lysate based hydrogels for 3D cell culture". Paper presented in 5th TERMIS World Congress, 2018.
  39. Custódio, Catarina A.; Cátia F. Monteiro; Joao F. Mano. "Humanized In-Vitro 3D Models Of Human Osteosarcoma For Drug Screening And Validation". Paper presented in 3rd EACR Conference - Goodbye Flat Biology: In Vivo Inspired Cancer Biology and Therapy, Berlin - Germany, 2018.
  40. Custódio, Catarina A.; Catia F. Monteiro; Joao F. Mano. "Human platelet lysates based hydrogels – a novel personalized 3D platform for spheroid invasion assessment". Paper presented in 3rd EACR Conference - Goodbye Flat Biology: In Vivo Inspired Cancer Biology and Therapy, Berlin, Germany, 2018.
  41. Custódio, Catarina A.; Monteiro, Cátia F.; Joao F. Mano. "Platelet lysates-based hydrogels for the development of in vitro disease models for osteosarcoma". Paper presented in Jornadas do CICECO, Aveiro, Portugal, 2018.
  42. Monteiro, Cátia F.; Custódio, Catarina A.; Mano, João F.. "Platelet lysate based hydrogels for the development of in vitro disease models for osteosarcoma". Paper presented in Jornadas do CICECO, 2018.
  43. Monteiro, Cátia F.; Custódio, Catarina A.; Mano, João F.. "Humanized In-Vitro 3D Models Of Human Osteosarcoma". Paper presented in EACR Conference - Goodbye Flat Biology: In Vivo Inspired Cancer Biology and Therapy, Berlin - Germany, 2018.
  44. Custódio, Catarina A.; Martins C. M.; Mano, João F.. "Multifunctional Laminarin Microparticles for Cell Adhesion and Expansion". Paper presented in 6th Portuguese Young Chemists Meeting, Setúbal – Portugal, 2018.
  45. Silva J. M.; Custódio, Catarina A.; Reis, Rui L.; Mano, João F.. "Multilayered Hollow Tubes for Cardiovascular Tissue Engineering". Paper presented in 4th TERMIS World Congress, Boston, USA, 2015.
  46. Custódio, Catarina A.; Gasperini L.,; Reis, Rui L.; Joao F. Mano. "Cell Type Specific Microspheres Incorporating Growth Factors as Injectable Cell Carriers for Tissue Repair". Paper presented in 4th TERMIS World Congress, Boston, USA, 2015.
  47. Custódio, Catarina A.; Reis, Rui L.; Mano, João F.. "Functional cell selective microparticles as injectable cell carriers for tissue engineering applications". Paper presented in TERMIS-Americas 2013 Annual Conference & Exposition, Atlanta, USA, 2013.
  48. Custódio, Catarina A.; Cerqueira, M.T.; Marques, A.P.; Reis, Rui L.; Mano, João F.. "Functional cell microcarriers- a new platform for cell separation and expansion". Paper presented in TERM STEM 2013 & 1st POLARIS Workshop, Porto, 2013.
  49. Costa, R.R.; Custódio, Catarina A.; Arias, F.J.; Rodríguez-Cabello J. C.; Mano, J. F.. "Self-Assembled Microcapsules with Tunable and Sustained Release of Macromolecules for Tissue Engineering". Paper presented in 3rd TERMIS World Congress, 2012, Vienna (Austria), 2012.
  50. Custódio, Catarina A.; Frias, A.M.; Del Campo, A.; Reis, Rui L.; Mano, João F.. "Chitosan membranes for spatially controlled cell adhesion and specific cell recruitment". Paper presented in 3rd TERMIS World Congress, 2012, Vienna (Austria), 2012.
  51. Custódio, Catarina A.; Reis, Rui L.; Mano, J. F.; Del Campo, A.. "Photopatterned chitosan for spatially defined cell cocultures". Paper presented in Euromat 2011, Montpellier, 2011.
  52. Costa, R.R.; Custódio, Catarina A.; Arias, F.J.; Rodríguez-Cabello, J.C.; Mano, J.F.. "Buildup of biomimetic and multiple stimuli responsive thin coatings of polysaccharides and recombinant biopolymers". Paper presented in 2nd Meeting of the Institute for Biotechnology and Bioengineering, 2010.
  53. Custódio, Catarina A.; Reis, Rui L.; Mano, João F.. "Comparison of adsorption and covalent attachment of proteins as strategies in surface modification of a natural-origin polymer". Paper presented in Frontiers in Polymer Science, Mainz, Germany, 2009.
  54. Custódio, Catarina A.; Alves, Catarina M; Reis, Rui L.; Mano, João F.. "Immobilization of biomolecules on chitosan surface for selective recruitment, controlled growth and differentiation of cells from mixed populations". Paper presented in TERMIS-EU 2008 Tissue Engineering International & Regenerative Medicine Society Meeting, 2008.
  55. Custódio, Catarina A.; Alves, Catarina M; Reis, Rui L.; Mano, João F.. "Studies of the efficiency of EDC/NHS as molecular-binders to chitosan surfaces". Paper presented in 5th Marie Curie Conference on "Synthesis and Applications of Self Assembling Materials at nano-scale, 2008.
Journal article
  1. Mariana Dias; Catarina A. Custódio; João F. Mano. "Human protein-based biomaterials in preclinical modelling". Nature Reviews Bioengineering (2026): https://doi.org/10.1038/s44222-026-00425-7.
    10.1038/s44222-026-00425-7
  2. Maria C. Mendes; Elisa A. G. Martins; Roman V. Chernozem; Polina V. Chernozem; Catarina C. Custódio; Roman A. Surmenev; Andrei L. Kholkin; Ana S. Silva; João F. Mano. "Osteogenic Differentiation Triggered by Intracellular Magnetoelectric Stimulation of Core–Shell Nanotransducers under Remotely Applied Magnetic Fields". ACS Nano (2025): https://doi.org/10.1021/acsnano.5c10509.
    10.1021/acsnano.5c10509
  3. Costa, Marcelo; Middleton, Herbert; Correia, Tiago; Soares, Ana Prates; Ellinghaus, Agnes; Jahn, Denise; Schmidt-Bleek, Oskar; et al. "Injectable, mechanically reinforced human-based nanocomposite for minimal invasive applications". Acta Biomaterialia (2025): https://doi.org/10.1016/j.actbio.2025.12.007.
    10.1016/j.actbio.2025.12.007
  4. Lucas S. Ribeiro; João Rocha Maia; Vítor M. Gaspar; Catarina A. Custódio; Emerson R. Camargo; Rita Sobreiro-Almeida; João F. Mano. "Nozzle Jamming Granularized Blood-Derived Proteins for Bioprinting Cell-Instructive Architectures". Aggregate (2025): https://doi.org/10.1002/agt2.70041.
    10.1002/agt2.70041
  5. Elisa A.G. Martins; Inês A. Deus; Maria C. Gomes; Ana S. Silva; João F. Mano; Catarina A. Custódio. "Human Chorionic Membrane-derived Tunable Hydrogels for Vascular Tissue Engineering Strategies". Advanced Healthcare Materials (2025): https://doi.org/10.1002/adhm.202401510.
    10.1002/adhm.202401510
  6. Monteiro, Cátia F.; Deus, Inês A.; Custódio, Catarina A.; Mano, Joao F.. Corresponding author: Monteiro, Cátia F.. "Biomaterials meet organ-on-chips – a perspective on tumor modeling". International Materials Reviews (2024): 1.
    Accepted • 10.1177/09506608241303436
  7. Cátia F. Monteiro; Catarina R. Almeida; Catarina A. Custódio; João F. Mano. "Modeling 3D Tumor Invasiveness to Modulate Macrophage Phenotype in a Human-Based Hydrogel Platform". Macromolecular Bioscience (2024): https://doi.org/10.1002/mabi.202400227.
    10.1002/mabi.202400227
  8. Sobreiro-Almeida, Rita; Santos, Sara C.; Decarli, Monize C.; Costa, Marcelo; Correia, Tiago R.; Babilotte, Joanna; Custódio, Catarina A.; Moroni, Lorenzo; Mano, João F.. "Leveraging Blood Components for 3D Printing Applications Through Programmable Ink Engineering Approaches". Advanced Science 11 47 (2024): https://doi.org/10.1002/advs.202406569.
    10.1002/advs.202406569
  9. Martins, Elisa A.G.; Deus, Inês A.; Gomes, Maria; Silva, Ana Sofia; Mano, Joao F.; Custódio, Catarina A.. Corresponding author: Custódio, Catarina A.. "Human Chorionic Membrane-derived Tunable Hydrogels for Vascular Tissue Engineering Strategies". Advanced Healthcare Materials 2401510 (2024): https://onlinelibrary.wiley.com/doi/epdf/10.1002/adhm.202401510.
    Published
  10. Sousa, Joana P.M.; Deus, Inês A.; Monteiro, Cátia F.; Custódio, Catarina A.; Gil, João; Papadimitriou, Lina; Ranella, Anthi; et al. "Amniotic Membrane-Derived Multichannel Hydrogels for Neural Tissue Repair". Advanced Healthcare Materials 13 27 (2024): https://doi.org/10.1002/adhm.202400522.
    Published • 10.1002/adhm.202400522
  11. Caiado Decarli, Monize; Ferreira, Helena P.; Sobreiro-Almeida, Rita; Teixeira, Filipa C.; Correia, Tiago R.; Babilotte, Joanna; Olijve, Jos; et al. "Embedding Bioprinting of Low Viscous, Photopolymerizable Blood-Based Bioinks in a Crystal Self-Healing Transparent Supporting Bath". Small Methods (2024): http://dx.doi.org/10.1002/smtd.202400857.
    10.1002/smtd.202400857
  12. Cátia F. Monteiro; Maria C. Gomes; Pankaj Bharmoria; Mara G. Freire; João A. P. Coutinho; Catarina A. Custódio; João F. Mano. "Human Platelet Lysate-Derived Nanofibrils as Building Blocks to Produce Free-Standing Membranes for Cell Self-Aggregation". ACS Nano (2024): https://doi.org/10.1021/acsnano.4c02790.
    10.1021/acsnano.4c02790
  13. Cátia F. Monteiro; Inês A. Deus; Inês B. Silva; Iola F. Duarte; Catarina A. Custódio; João F. Mano. "Tumor-On-A-Chip Model Incorporating Human-Based Hydrogels for Easy Assessment of Metastatic Tumor Inter-Heterogeneity". Advanced Functional Materials (2024): https://doi.org/10.1002/adfm.202315940.
    10.1002/adfm.202315940
  14. Joana P. M. Sousa; Inês A. Deus; Cátia F. Monteiro; Catarina A. Custódio; Emmanuel Stratakis; João F. Mano; Paula A. A. P. Marques. "Comparative analysis of aligned and random amniotic membrane-derived cryogels for neural tissue repair". Biomaterials Science (2024): https://doi.org/10.1039/D4BM00364K.
    10.1039/D4BM00364K
  15. Sara C. Santos; Catarina A. Custódio; João F. Mano. "Photocrosslinkable microgels derived from human platelet lysates: injectable biomaterials for cardiac cell culture". Biomaterials Science (2024): https://doi.org/10.1039/D3BM01933K.
    10.1039/D3BM01933K
  16. Zargarzadeh, Mehrzad; Gomes, Maria C.; Patrício, Sónia G.; Custódio, Catarina A.; Mano, João F.. "A Self-Sustaining Hydrogels with Autonomous Supply of Nutrients and Bioactive Domains for 3D Cell Culture". Advanced Functional Materials 33 48 (2023): http://dx.doi.org/10.1002/adfm.202214372.
    10.1002/adfm.202214372
  17. Gomes MC; Pinho AR; Custódio C; Mano JF. "Self-Assembly of Platelet Lysates Proteins into Microparticles by Unnatural Disulfide Bonds for Bottom-Up Tissue Engineering.". Advanced materials (Deerfield Beach, Fla.) (2023): http://europepmc.org/abstract/med/37354139.
    10.1002/adma.202304659
  18. Ladeira BMF; Gomes MC; Custódio CA; Mano JF. "High-Throughput Production of Microsponges from Platelet Lysate for Tissue Engineering Applications.". Tissue engineering. Part C, Methods (2022): http://europepmc.org/abstract/med/35343236.
    10.1089/ten.tec.2022.0029
  19. "High-Throughput Manufacturing of Microsponges from Methacryloyl Platelet Lysate for Cell Delivery". Tissue Engineering Part C (2022):
    Under revision
  20. Santos, Sara C.; Custódio, Catarina A.; Mano, João F.. "Human Protein-Based Porous Scaffolds as Platforms for Xeno-Free 3D Cell Culture". Advanced Healthcare Materials (2022): 2102383. http://dx.doi.org/10.1002/adhm.202102383.
    10.1002/adhm.202102383
  21. Mehrzad Zargarzadeh; A. Sofia Silva; Cláudia Nunes; Manuel A. Coimbra; Catarina A. Custódio; João F. Mano. "Self-glucose feeding hydrogels by enzyme empowered degradation for 3D cell culture". Materials Horizons (2022): https://doi.org/10.1039/D0MH01982H.
    10.1039/D0MH01982H
  22. Bruno M. Ladeira; Catarina A. Custódio; João F. Mano. "Core–shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine". Biomaterials Science (2022): https://doi.org/10.1039/D1BM01974K.
    10.1039/D1BM01974K
  23. Deus, Inês A.; Santos, Sara C.; Custódio, Catarina A.; Mano, João F.. "Designing highly customizable human based platforms for cell culture using proteins from the amniotic membrane". Materials Science and Engineering: C (2021): 112574. http://dx.doi.org/10.1016/j.msec.2021.112574.
    Published • 10.1016/j.msec.2021.112574
  24. Monteiro CF; Custódio CA; Mano JF. "Bioengineering a humanized 3D tri-culture osteosarcoma model to assess tumor invasiveness and therapy response.". Acta biomaterialia (2021): http://europepmc.org/abstract/med/34303015.
    10.1016/j.actbio.2021.07.034
  25. Tavares, M.T.; Santos, S.C.; Custódio, C.A.; Farinha, J.P.S.; Baleizão, C.; Mano, J.F.. "Platelet lysates-based hydrogels incorporating bioactive mesoporous silica nanoparticles for stem cell osteogenic differentiation". Materials Today Bio 9 (2021): 100096. http://dx.doi.org/10.1016/j.mtbio.2021.100096.
    10.1016/j.mtbio.2021.100096
  26. C. S. Dias; C. A. Custódio; G. C. Antunes; M. M. Telo da Gama; J. F. Mano; N. A. M. Araújo. "Modeling of Cell-Mediated Self-Assembled Colloidal Scaffolds". ACS Applied Materials & Interfaces (2020): https://doi.org/10.1021/acsami.0c13457.
    10.1021/acsami.0c13457
  27. Inês A. Deus; João F. Mano; Catarina A. Custódio. "Perinatal tissues and cells in tissue engineering and regenerative medicine". Acta Biomaterialia 110 (2020): 1-14. https://doi.org/10.1016/j.actbio.2020.04.035.
    10.1016/j.actbio.2020.04.035
  28. Mehrzad Zargarzadeh; Adérito J.R. Amaral; Catarina A. Custódio; João F. Mano. "Biomedical applications of laminarin". Carbohydrate Polymers 232 (2020): 115774-115774. https://doi.org/10.1016/j.carbpol.2019.115774.
    10.1016/j.carbpol.2019.115774
  29. Monteiro, Cátia F.; Santos, Sara C.; Custódio, Catarina A.; Mano, João F.. "Human Platelet Lysates-Based Hydrogels: A Novel Personalized 3D Platform for Spheroid Invasion Assessment". Advanced Science (2020): 1902398. http://dx.doi.org/10.1002/advs.201902398.
    10.1002/advs.201902398
  30. C.R. Martins; C.A. Custódio; J.F. Mano. "Multifunctional laminarin microparticles for cell adhesion and expansion". Carbohydrate Polymers 202 (2018): 91-98. https://doi.org/10.1016/j.carbpol.2018.08.029.
    10.1016/j.carbpol.2018.08.029
  31. Monteiro, Cátia F.; Custódio, Catarina; Mano, João F.. "Three-Dimensional Osteosarcoma Models for Advancing Drug Discovery and Development". Advanced Therapeutics 2 3 (2018): 1800108. http://dx.doi.org/10.1002/adtp.201800108.
    Published • 10.1002/adtp.201800108
  32. Santos, Sara C.; Custódio, Catarina; Mano, João F.. "Photopolymerizable Platelet Lysate Hydrogels for Customizable 3D Cell Culture Platforms". Advanced Healthcare Materials 7 23 (2018): 1800849. http://dx.doi.org/10.1002/adhm.201800849.
    Published • 10.1002/adhm.201800849
  33. Santos, Sara C.; Sigurjonsson ÓE; Custódio, Catarina; João F. Mano. "Blood Plasma Derivatives for Tissue Engineering and Regenerative Medicine Therapies.". Tissue engineering. Part B, Reviews (2018): http://europepmc.org/abstract/med/29737237.
    Published • 10.1089/ten.teb.2018.0008
  34. Custódio, Catarina; João F. Mano. "Cell Surface Engineering to Control Cellular Interactions". ChemNanoMat 2 5 (2016): 376-384. https://doi.org/10.1002/cnma.201600047.
    Published • 10.1002/cnma.201600047
  35. Silva, J.M.; Custódio, Catarina A.; Reis, R.L.; Mano, J.F.. "Multilayered Hollow Tubes as Blood Vessel Substitutes". ACS Biomaterials Science and Engineering 2 12 (2016): 2304-2314. http://www.scopus.com/inward/record.url?eid=2-s2.0-85006036367&partnerID=MN8TOARS.
    Published • 10.1021/acsbiomaterials.6b00499
  36. Custódio, Catarina A.; Reis, R.L.; Mano, J.F.. "Photo-Cross-Linked Laminarin-Based Hydrogels for Biomedical Applications". Biomacromolecules 17 5 (2016): 1602-1609. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973630001&partnerID=MN8TOARS.
    Published • 10.1021/acs.biomac.5b01736
  37. Rodrigues, L.C.; Custódio, Catarina; Reis, R.L.; Mano, J.F.. "Light responsive multilayer surfaces with controlled spatial extinction capability". Journal of Materials Chemistry B 4 8 (2016): 1398-1403. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959348872&partnerID=MN8TOARS.
    Published • 10.1039/c5tb02606g
  38. Oliveira, M.B.; Custódio, C.A.; Gasperini, L.; Reis, R.L.; Mano, J.F.. "Autonomous osteogenic differentiation of hASCs encapsulated in methacrylated gellan-gum hydrogels". Acta Biomaterialia 41 (2016): 119-132. http://www.scopus.com/inward/record.url?eid=2-s2.0-84971601488&partnerID=MN8TOARS.
    10.1016/j.actbio.2016.05.033
  39. Martins, N.I.; Sousa, M.P.; Custódio, C.A.; Pinto, V.C.; Sousa, P.J.; Minas, G.; Cleymand, F.; Mano, J.F.. "Multilayered membranes with tuned well arrays to be used as regenerative patches". Acta Biomaterialia (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85018325310&partnerID=MN8TOARS.
    10.1016/j.actbio.2017.04.021
  40. Custódio, Catarina A.; Cerqueira, M.T.; Marques, A.P.; Reis, R.L.; Mano, J.F.. "Cell selective chitosan microparticles as injectable cell carriers for tissue regeneration". Biomaterials 43 1 (2015): 23-31. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922996872&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2014.11.047
  41. Custódio, Catarina A.; San Miguel-Arranz, V.; Gropeanu, R.A.; Gropeanu, M.; Wirkner, M.; Reis, R.L.; Mano, J.F.; Del Campo, A.. "Photopatterned antibodies for selective cell attachment". Langmuir 30 33 (2014): 10066-10071. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906656874&partnerID=MN8TOARS.
    Published • 10.1021/la502688h
  42. Custódio, Catarina A.; Reis, R.L.; Mano, J.F.. "Engineering Biomolecular Microenvironments for Cell Instructive Biomaterials". Advanced Healthcare Materials 3 6 (2014): 797-810. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902243790&partnerID=MN8TOARS.
    Published • 10.1002/adhm.201300603
  43. Neto, A.I.; Correia, C.R.; Custódio, Catarina; Mano, J.F.. "Biomimetic miniaturized platform able to sustain arrays of liquid droplets for high-throughput combinatorial tests". Advanced Functional Materials 24 32 (2014): 5096-5103. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906783657&partnerID=MN8TOARS.
    Published • 10.1002/adfm.201400503
  44. Silva, J.M.; Duarte, A.R.C.; Custódio, Catarina; Sher, P.; Neto, A.I.; Pinho, A.C.M.; Fonseca, J.; Reis, R.L.; Mano, J.F.. "Nanostructured Hollow Tubes Based on Chitosan and Alginate Multilayers". Advanced Healthcare Materials 3 3 (2014): 433-440. http://www.scopus.com/inward/record.url?eid=2-s2.0-84895429567&partnerID=MN8TOARS.
    Published • 10.1002/adhm.201300265
  45. Custódio, Catarina A.; Santo, V.E.; Oliveira, M.B.; Gomes, M.E.; Reis, R.L.; Mano, J.F.. "Functionalized microparticles producing scaffolds in combination with cells". Advanced Functional Materials 24 10 (2014): 1391-1400. http://www.scopus.com/inward/record.url?eid=2-s2.0-84895923617&partnerID=MN8TOARS.
    Published • 10.1002/adfm.201301516
  46. Costa, Rui R.; Custódio, Catarina A.; Arias, Francisco J.; Rodríguez-Cabello, José C.; Mano, João F.. "Nanostructured and thermoresponsive recombinant biopolymer-based microcapsules for the delivery of active molecules". Nanomedicine: Nanotechnology, Biology and Medicine 9 7 (2013): 895-902. http://dx.doi.org/10.1016/j.nano.2013.01.013.
    Published • 10.1016/j.nano.2013.01.013
  47. Ana Catarina Lima; Custódio, Catarina A.; Carmen Alvarez-Lorenzo; João F. Mano. "Polymer Particles: Biomimetic Methodology to Produce Polymeric Multilayered Particles for Biotechnological and Biomedical Applications (Small 15/2013)". Small 9 15 (2013): 2486-2486. http://dx.doi.org/10.1002/smll.201370089.
    Published • 10.1002/smll.201370089
  48. Lima, A.C.; Custódio, Catarina; Alvarez-Lorenzo, C.; Mano, J.F.. "Biomimetic methodology to produce polymeric multilayered particles for biotechnological and biomedical applications". Small 9 15 (2013): 2487-2492. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885181437&partnerID=MN8TOARS.
    Published • 10.1002/smll.201202147
  49. Custódio, Catarina; Frias, A.M.; del Campo, A.; Reis, R.L.; Mano, J.F.. "Selective cell recruitment and spatially controlled cell attachment on instructive chitosan surfaces functionalized with antibodies". Biointerphases 7 1-4 (2012): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871130354&partnerID=MN8TOARS.
    Published • 10.1007/s13758-012-0065-3
  50. Neto, A.I.; Custódio, Catarina A.; Song, W.; Mano, J.F.. "High-throughput evaluation of interactions between biomaterials, proteins and cells using patterned superhydrophobic substrates". Soft Matter 7 9 (2011): 4147-4151. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955026925&partnerID=MN8TOARS.
    Published • 10.1039/c1sm05169e
  51. Costa, R.R.; Custódio, Catarina; Arias, F.J.; Rodríguez-Cabello, J.C.; Mano, J.F.. "Layer-by-layer assembly of chitosan and recombinant biopolymers into biomimetic coatings with multiple stimuli-responsive properties". Small 7 18 (2011): 2640-2649. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052779197&partnerID=MN8TOARS.
    Published • 10.1002/smll.201100875
  52. Custódio, Catarina A.; Alves, C. M.; Reis, R. L.; Mano, J. F.. "Immobilization of fibronectin in chitosan substrates improves cell adhesion and proliferation". Journal of Tissue Engineering and Regenerative Medicine 4 4 (2010): 316-323. http://dx.doi.org/10.1002/term.248.
    Published • 10.1002/term.248
  53. Praveen Sher; Catarina A. Custódio; João. F. Mano. "Layer-by-layer assembly: Layer-By-Layer Technique for Producing Porous Nanostructured 3D Constructs Using Moldable Freeform Assembly of Spherical Templates (Small 23/2010)". Small 6 23 (2010): 2643-2643. http://dx.doi.org/10.1002/smll.201090084.
    Published • 10.1002/smll.201090084
  54. Sher, P.; Custódio, Catarina A. (0A10-D092-BD3C); Mano, J.F.. "Layer-by-layer technique for producing porous nanostructured 3D constructs using moldable freeform assembly of spherical templates". Small 6 23 (2010): 2644-2648. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649942073&partnerID=MN8TOARS.
    Published • 10.1002/smll.201001066
  55. Wenlong Song; Diana D. Veiga; Custódio, Catarina A. (0A10-D092-BD3C); João F. Mano. "Superhydrophobic Coatings: Bioinspired Degradable Substrates with Extreme Wettability Properties (Adv. Mater. 18/2009)". Adv. Mater. 21 18 (2009): NA-NA. http://dx.doi.org/10.1002/adma.200990062.
    Published • 10.1002/adma.200990062
  56. Song, W.; Veiga, D.D.; Custódio, Catarina A. (0A10-D092-BD3C); Mano, J.F.. "Bioinspired degradable substrates with extreme wettability properties". Advanced Materials 21 18 (2009): 1830-1834. http://www.scopus.com/inward/record.url?eid=2-s2.0-66749087667&partnerID=MN8TOARS.
    Published • 10.1002/adma.200803680
  57. Costa, R.R.; Custódio, Catarina A. (0A10-D092-BD3C); Testera, A.M.; Arias, F.J.; Rodríguez-Cabello, J.C.; Alves, N.M.; Mano, J.F.. "Stimuli-responsive thin coatings using elastin-like polymers for biomedical applications". Advanced Functional Materials 19 20 (2009): 3210-3218. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350452405&partnerID=MN8TOARS.
    Published • 10.1002/adfm.200900568
Journal issue
  1. Custódio, Catarina A.; Silva, A. Sofia; Clara R. Correia. "Design and Fabrication of Soft Materials". Biomimetics (2020): https://www.mdpi.com/journal/biomimetics/special_issues/soft_materials.
    Accepted • Editor
Newsletter article
  1. "Bluepharma-U.Coimbra Award for UA project of bioplatforms for cell culture", https://www.ua.pt/en/news, 2020, https://www.ua.pt/pt/noticias/16/63673.
  2. Custódio, Catarina A.; Borges, João F.; Amorim, Sara; Araújo, Ana R.; Moro, Artur J.; Mendes, Leonardo. "The Next Generation of Portuguese Chemists", https://www.chemistryviews.org/, 2018
Preprint
  1. Piedade F; Santos S; Ferreira B; Mano J; Custódio C; Almeida C. "Taking Advantage of 3D Human Cell Culture Platforms to Study Pulmonary Fibrotic Diseases". 2022. http://europepmc.org/abstract/PPR/PPR478044.
    10.22541/au.164913677.73849537/v1
Thesis / Dissertation
  1. Custódio, Catarina A.. "Immobilization of biomolecules into biodegradable polymeric based substrates for selective recruitment and adhesion of cells for tissue engineering applications". PhD, Universidade do Minho, 2013. https://repositorium.sdum.uminho.pt/handle/1822/28881?mode=full.

Artistic / Performance

Visual artwork
  1. Lucas Ribeiro; João Rocha Maia; Gaspar, Vítor; Custódio, Catarina A.; Emerson Camargo; Sobreiro-Almeida, Rita; Mano, Joao F.. Inside Front Cover: Aggregate Volume 6, Issue 7.
    10.1002/agt2.70107

Intellectual property

Patent
  1. Sobreiro-Almeida, Rita; Santos, Sara C.; Custódio, Catarina A.; Tiago R. Correia; Mano, Joao F.. 2025. "GLOBULAR PROTEIN-BASED COMPOSITIONS, METHODS AND USES THEREOF". Portugal.
    Granted/Issued
  2. Mano, Joao F.; Maria C. Gomes; Custódio, Catarina A.. 2024. "PLATELET LYSATE-BASED MICROPARTICLES, METHODS AND USES THEREOF - WO-2024127155-A1". Portugal.
    Granted/Issued
  3. Mano, Joao F.; Maria C. Gomes; Custódio, Catarina A.. 2024. "MICROPARTICULAS À BASE DE LISADOS DE PLAQUETAS, MÉTODOS DE PREPARAÇÃO E SUAS APLICAÇÕES". Portugal.
    Pending
  4. Custódio, Catarina A.. 2021. "HUMAN PLACENTAL MEMBRANE BASED HYDROGEL COMPOSITION, PROCESSES AND USES THEREOF". Portugal.
    Pending
  5. Custódio, Catarina. 2019. "HYDROGELS BASED ON BLOOD PLASMA COMPONENTS, PROCESS AND USES THEREOF".
    Granted/Issued
  6. Custódio, Catarina A.; Santos, Sara C.; Inês A. Deus; João. F. Mano. 2019. "HUMAN PLACENTAL MEMBRANE BASED HYDROGEL COMPOSITION, PROCESSES AND USES THEREOF".
    Pending
  7. Custódio, Catarina A.. 2012. "PROCESSO PARA DEPOSIÇÃO DE BIOMATERIAIS EM SUBSTRATOS REPELENTES A ÁGUA E RESULTANTES BIOMATERIAIS".
    Allowed
Trademark
  1. 2019. "METATISSUE".
    Registered

Other

Other output
  1. Volumetric Bioprinting of Self-Sustaining Hydrogels and Their Chondrogenic Potential-Manuscript in Preparation. 2024. Zargarzadeh, Mehrzad; Custódio, Catarina A.; João F. Mano; Jos Malda; Levato, Riccardo.
  2. Synthetic organelles as intracellular glucose suppliers for augmented cell viability- Manuscript in Preparation. 2024. Zargarzadeh, Mehrzad; Custódio, Catarina A.; Mano, Joao F..
  3. Platelet Lysate-Based Hydrogels as a 3D Scaffold for Organoid Cultivation-Manuscript in Preparation. 2024. Zargarzadeh, Mehrzad; Custódio, Catarina A.; Mano, Joao F..
Spin-off company
  1. 2018. METATISSUE (JFCC-Biosolutions). Design and development of novel human based soft materials for 3D cell culture.. metatissue.com.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/04/16 Inovação na Indústria Farmacêutica: A Relevância das Proteínas Humanas na Criação de Modelos In Vitro Fisiologicamente Relevantes 2ª Edição do Gen Sci
Scientific Junior Value (Aveiro, Portugal)
2024/05 Revolutionizing drug screening: harnessing human protein-based materials for ethical and accelerated in vitro testing 12th World Biomaterials Congress, WBC 2024
The Korean Society for Biomaterial (Daegu, South Korea)
2023/09 Advancing tumor modeling and drug screening with a dynamic system integrating a 3D human-based hydrogel to support spheroid invasion European Society for Biomaterials ESB2023
European Society for Biomaterials (Davos, Switzerland)
2023/09 Leveraging host-guest interactions to produce highly reshapable soft hydrogels from proteins of human origin European Society for Biomaterials ESB2023
European Society for Biomaterials (Davos, Switzerland)
2022/04/01 Tec2Med - Technology And Innovation In Medicine Tec2Med
(Lisboa, Portugal)
2021/11/15 Human protein based platforms for 3D cell culture - a new era for personalized engineering tissues 6th TERMIS World Congress
Tissue Engineering and Regenerative Medicine International Society, Inc. (TERMIS) (Maastricht, Netherlands)
2021/11/15 An engineered human osteosarcoma-on-a-chip for tumor invasion modelling in a dynamic system TERMIS World Congress
Tissue Engineering and Regenerative Medicine International Society, Inc. (TERMIS) (Maastricht, Netherlands)
2021/09/05 Hybrid Multicomponent Laminaran/Platelet lysate-based hydrogels 31st Annual Conference of the European Society for Biomaterials (ESB 2021)
European Society for Biomaterials (Porto, Portugal)
2021/09/05 Photocrosslinkable hydrogels from solubilized extracellular matrix of the amniotic membrane 31st Annual Conference of the European Society for Biomaterials (ESB 2021)
European Society for Biomaterials (Porto)
2021/09/05 Accelerating drug development with human protein based platforms for in vitro 3D cell culture and disease modelling 31st Annual Conference of the European Society for Biomaterials (ESB 2021)
European Society for Biomaterials (Porto, Portugal)
2021/09 Human protein-based sponges for fully xeno-free cell culture platforms 31st Annual Conference of the European Society for Biomaterials (ESB 2021)
European Society for Biomaterials (Porto, Portugal)
2020/12/11 A 3D human based hydrogel to support spheroid invasion for disease modelling and drug screening applications 11th World Biomaterials Congress
Society For Biomaterials (United Kingdom)
2020/12 Laminarin hydrogels as self-feeding platforms for 3D cell culture 11th World Biomaterials Congress, Glasgow, Scotland
Society For Biomaterials (United Kingdom)
2020/05 Laminarin as self-feeding platforms for 3D cell culture World Biomaterials Congress 2020
(United Kingdom)
2020/05 Human based cell culture platforms for tissue engineering applications Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Meeting 2020 (TERMIS EU 2020)
Tissue Engineering and Regenerative Medicine International Society (Manchester, United Kingdom)
2020/05 A 3D human-based hydrogel to support spheroid invasion for disease modelling and drug screening applications 11th World Biomaterials Congress, Glasgow, Scotland
(Glasgow, United Kingdom)
2019/10 Innovative Biomedical System Based on Controlled Enzymatically Degradation of Hydrogels 6th EPNOE International Polysaccharide Conference
Cellulose and Renewable Division of the American Chemistry Society (ACS) and Cellulose Society of Japan (CSJ) (Aveiro, Portugal)
2019/05 Human platelet lysate-based hydrogels – a humanized 3D platform for disease modelling guided by tissue engineering European Chapter of the Tissue Engineering and Regenerative Medicine International Society, Inc. (TERMIS)
Tissue Engineering and Regenerative Medicine International Society (Rhodes, Greece)
2019/05 Human platelet lysates-based hydrogels: a novel platform for tissue engineering applications TERMIS European Chapter Meeting 2019
Tissue Engineering and Regenerative Medicine International Society (Rhodes, Greece)
2018/10 Designing humanized hydrogels toward tissue engineering and disease modeling 13th International Chemical and Biological Engineering Conference (CHEMPOR 2018), Aveiro, Portugal
University of Aveiro and Ordem dos Engenheiros (Aveiro, Portugal)
2018/09/20 Biomaterials for Tissue Engineering Advanced Course on Carbohydrates
University of Aveiro (Aveiro, Portugal)
2018/09 Platelet lysate based hydrogels with tunable mechanical properties as platforms for 3D cell culture 9th Annual Meeting of the European Society for Biomaterials
European Society for Biomaterials (Maastricht, Netherlands)
2017/12 Freestanding Multilayered Membranes patterned with Micro-Reservoirs as potential Regenerative Paths. 8th Annual TERMIS - Americas Conference and Exhibition
Tissue Engineering and Regenerative Medicine International Society (Charlotte, United States)
2014/08 Antibody coated microparticles to fabricate functional 3D constructs in combination with cells 26th Annual Conference European Society for Biomaterials
European Society for Biomaterials (Liverpool, United Kingdom)
2014/06 Functional chitosan microcarriers for selective cell attachment and expansion Termis EU 2014
Tissue Engineering and Regenerative Medicine International Society (Genova, Italy)
2013/05 Functionalized microgels for controlled stem cell proliferation and differentiation 8th International Annual Meeting of the Portuguese Society for Stem Cells and Cell Therapies
Portuguese Society for Stem Cells and Cell Therapies (Faro, Portugal)
2013/04 Engineering Functional Microparticles to Fabricate Instructive Cell Microenvironments Society For Biomaterials - 2013 Annual Meeting & Exposition
Society For Biomaterials (Boston, United States)
2012/10 Development of bioactive constructs through cell crosslinking for tissue regeneration TERM STEM 2012
TERM STEM (Guimarães, Portugal)
2011/06 Nanostructured Films Exhibiting Multiple Stimuli Responsive Behavior and Improved Cell Adhesion for Tissue Engineering European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS)
Tissue Engineering and Regenerative Medicine International Society (Granada, Spain)
2009/09 Response of Cells on Bioinspired Degradable Substrates with Extreme Wettability Properties TERMIS 2009 WC
Tissue Engineering and Regenerative Medicine International Society (Seoul, South Korea)
2009/09 Novel Thin Biomimetic Coatings for Polysaccharides with Smart Behavior Based on Recombinant Polymers for Tissue Engineering Applications 2nd World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS)
Tissue Engineering and Regenerative Medicine International Society (Seoul, South Korea)

Supervision

Thesis Title
Role		 Degree Subject (Type)
Institution / Organization
2023/11 - Current HeartSafe: Developing Human Protein-Based Cardiac Models for Safer Drug Testing and Cardiotoxicity Screening
Co-supervisor
 PhD in Biotechnology (PhD)
Universidade de Aveiro, Portugal

METATISSUE, Portugal
2022/03 - Current Scale up of the processing of perinatal tissue to synthesize human based hydrogels to a pilot unit
Supervisor of Filipe Marques Oliveira
 Chemical Engineering (Master)
Universidade de Aveiro, Portugal

Universidade de Aveiro Departamento de Química, Portugal
2022/02 - Current Development of bioactive human based cryogels to fabricate ready-to-use bioinspired scaffolds for bone tissue engineering
Co-supervisor of Elisa Alexandra Gonçalves Martins
 Doctoral Program in Biotechnology (PhD)
Universidade de Aveiro CICECO, Portugal

Universidade de Aveiro Departamento de Química, Portugal
2021/11/11 - Current Heart-on-a-chip: a fully-human 3D printed device for disease modelling and drug screening
Co-supervisor of Inês Araújo Deus
 Doctorate in Biotechnology (PhD)
Universidade de Aveiro CICECO, Portugal

Universidade de Aveiro Departamento de Química, Portugal
2021/10 - Current Optimization of the synthesis of platforms for 3D culture produced from the amniotic membrane
Supervisor of Miguel Vigário
 Master in Biotechnology (Master)
Universidade de Aveiro CICECO, Portugal

Universidade de Aveiro Departamento de Química, Portugal
2021/09 - Current Are human based materials the future of 3D cell cultures?
Supervisor of Inês Barbosa Silva
 Master in Biotechnology (Master)
Universidade de Aveiro CICECO, Portugal

Universidade de Aveiro Departamento de Química, Portugal
2021/09 - Current Chemical modification of human-derived proteins to develop personalized cell culture platforms and bioinks
Supervisor
 Master in Molecular and Bioengineering Biotechnology (Master)
Universidade de Aveiro CICECO, Portugal

Universidade de Aveiro Departamento de Química, Portugal
2019/12 - Current Chemical modification of human proteins for the preparation of hydrogels with tunable mechanical properties
Supervisor of Maria Clara Gomes
 Junior Researcher hired for the project BEAT (PTDC/BTM-MAT/30869/2017) (Other)
Universidade de Aveiro CICECO, Portugal
2019 - Current Human plasma derived hydrogels for myocardial tissue engineering
Co-supervisor of Sara Catarina Nunes da Silva Santos
 Doctoral Program in Biotechnology (PhD)
Universidade de Aveiro Departamento de Química, Portugal
2019 - Current Osteosarcoma-on-a-chip: A physiologically relevant human-based microfluidic platform for drug screening
Co-supervisor of Cátia Filipa Rodrigues Monteiro
 Doctoral Program in Biotechnology
Universidade de Aveiro Departamento de Química, Portugal
2019 - Current Innovative Biomedical System Based on Controlled Enzymatically Degradation of Hydrogels
Co-supervisor of Mehrzad Zargarzadeh
 Doctoral Program in Biotechnology (PhD)
Universidade de Aveiro Departamento de Química, Portugal
2022/02/15 - 2022/11/15 Development of human platelet-based materials
Supervisor of Bruno Ladeira
Universidade de Aveiro CICECO, Portugal

Universidade de Aveiro Departamento de Química, Portugal
2022/02/15 - 2022/11/15 Development of bioinks derived from the extracellular matrix of the amniotic membrane.
Supervisor of André Filipe Dias Lima
Universidade de Aveiro CICECO, Portugal

Universidade de Aveiro Departamento de Química, Portugal
2020/10/01 - 2021/12/10 Micropatterned platelet lysate based membranes for cardiac tissue regeneration
Supervisor
 Biotecnologia (Master)
Universidade de Aveiro, Portugal
2020/10/01 - 2021/12/06 Development of platelet lysate based scaffolds from microcapsules for regeneration post-myocardial infarction
Supervisor
 Biotecnologia (Master)
Universidade de Aveiro, Portugal
2021/02/01 - 2021/12 Scale up of a plasma protein hydrogel synthesis process for a pilot unit
Supervisor
 Engenharia Química (Master)
Universidade de Aveiro, Portugal
2020/11/01 - 2021/12 Optimization of the synthesis and manufacturing process of platforms for 3D cell culture derived from human blood plasma proteins
Supervisor
 Biotecnologia
Universidade de Aveiro, Portugal
2020/01/10 - 2021/11/30 Platelet lysates-based hydrogels as 3D cell culture platforms for cardiac regeneration
Supervisor
 Bioquímica (Master)
Universidade de Aveiro, Portugal
2021/01/03 - 2021/11/15 Development of 3D hydrogels for axonal regeneration
Co-supervisor
 Biomedical engineering (Master)
Universidade de Aveiro Instituto de Biomedicina, Portugal
2020/10 - 2021/11 Behaviour of cells confined to topographic hydrogels
Co-supervisor
 Biotecnologia (Master)
Universidade de Aveiro, Portugal
2019 - 2021/02/26 Extracellular matrix scaffolds for Cardiac Tissue Engineering
Supervisor of Elisa Alexandra Gonçalves Martins
 Master’s degree in Materials and Biomedical Devices
Universidade de Aveiro Departamento de Química, Portugal
2019 - 2021/02/25 Taking advantage of 3D humanized in vitro models to study pulmonary diseases
Supervisor of Francisca Rodrigues da Piedade
 Master in Biochemistry (Master)
Universidade de Aveiro Departamento de Química, Portugal
2019/09 - 2021/02/22 Development of a platelet lysates-based hydrogel for nerve regeneration
Co-supervisor
 Biomedicina Molecular (Master)
Universidade de Aveiro, Portugal
2019 - 2021/02/19 Protein based scaffolds and matrices for 3D cell culture
Supervisor of Ana Miguel da Silva Loureiro
 Master in Biochemistry (Master)
Universidade de Aveiro Departamento de Química, Portugal
2020 - 2021 Platelet Lysate Hydrogels for Myocardial Repair
Supervisor of Inês Araújo Deus
Universidade de Aveiro CICECO, Portugal
2019/02/01 - 2019/10/31 Development and characterization of platelet lysates based hydrogels for cardiac cell culture
Supervisor of Cátia Filipa Rodrigues Monteiro
Universidade de Aveiro CICECO, Portugal
2018 - 2019 Preparation of a hydrogel from human fetal membranes for 3D cell culture
Supervisor of Inês Araújo Deus
 Master in Biotechnology (Master)
Universidade de Aveiro Departamento de Química, Portugal
2017 - 2018 Platelet lysate based gels for the development of in vitro disease models for bone cancer
Supervisor of Cátia Filipa Rodrigues Monteiro
 Master in Biothecnology (Master)
Universidade de Aveiro Departamento de Química, Portugal
2017 - 2018 Multifunctional microparticles to produce 3D polymeric structures with controlled organization
Supervisor of Margarida Seco Martins Marques Neves
Degree in Biotechnology (Degree)
Universidade de Aveiro Departamento de Química, Portugal
2016 - 2017 Development of injectable hydrogels derived from human platelet lysates
Supervisor of Sara Catarina Nunes da Silva Santos
 Master in Biochemistry (Master)
Universidade de Aveiro Departamento de Química, Portugal
2016 - 2017 Platelet lysates loaded laminarin microparticles for cell attachment and expansion
Supervisor of Cláudia Isabel Rodrigues Martins
 Master in Biotechnology (Master)
Universidade de Aveiro Departamento de Química, Portugal

Event organisation

Event name
Type of event (Role)		 Institution / Organization
2022/03 - Current Symposium in the 32nd Annual Conference of the European Society of Biomaterials Title of the symposium: Advances in the design of multifunctional and cell-instructive hydrogels for tissue engineering (2022/09/04 - 2022/09/08)
Conference (Member of the Scientific Committee)
 European Society of Biomaterials, France
2019/10/10 - 2019/10/12 Techdays 2019 Aveiro (2019/10/10 - 2019/10/12)
Exhibition (Co-organisor)
 Universidade de Aveiro, Portugal
2017/12 - 2017/12 COST-Training School: Understanding bioadhesion in vitro, December 2017 - Aveiro, Portugal. http://www.enba4.eu/2017/06/28/biomimetic-adhesive-polymers-and-hydrogels/ (2017/12)
Conference (Member of the Organising Committee)
 Universidade de Aveiro CICECO, Portugal
2017/11/06 - 2017/11/08 International Symposium on Bioinspired Macromolecular Systems (ISMBS), November 2017 – Aveiro, Portugal (2017/11)
Conference
 Universidade de Aveiro CICECO, Portugal
2017/10/12 - 2017/10/14 Techdays 2017 Aveiro (2019/10/12 - 2019/10/14)
Exhibition (Co-organisor)
 Universidade de Aveiro, Portugal
2016/09/15 - 2016/09/17 Techdays 2016 Aveiro (2017/09/15 - 2017/09/17)
Exhibition (Co-organisor)
 Universidade de Aveiro, Portugal
2016/04 - 2016/04 5th Portuguese Young Chemists Meeting (5th PYCheM) and 1st European Young Chemists Meeting (1st EYCheM) http://5pychem.eventos.chemistry.pt/ (2016/04 - 2016/04)
Conference (President of the Organising Committee)
 Sociedade Portuguesa de Química, Portugal

Event participation

Activity description
Type of event		 Event name
Institution / Organization
2022/02/21 - 2022/02/22 23.ª edição das JorTec – Jornadas Tecnológicas JorTec'22 Engenharia Biomédica - Engenharia de Tecidos
Round table
 JorTec'22 Engenharia Biomédica - Jornadas Tecnológicas
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/11/01 - 2021/11/04 2021 Web Summit- The world's largest technology conference
Congress
 Web Summit 2021
Startup Portugal, Portugal
2021/03/17 - 2021/03/17 Human platelet lysates based hydrogels as 3D platforms for tissue engineering and disease modelling applications
Symposium
 2nd Aveiro-Osaka Symposium
Universidade de Aveiro, Portugal
2019/10/21 - 2019/10/21 3rd Training School on Bioinspired Adhesive Hydrogels and Polymers
Workshop
 COST Action- 3rd Training School on Bioinspired Adhesive Hydrogels and Polymers
Universidade de Aveiro CICECO, Portugal
2018/07/02 - 2018/07/04 Ciência 2018 - Encontro com a Ciência e Tecnologia em Portugal
Meeting
 Ciência 2018 - Encontro com a Ciência e Tecnologia em Portugal
Fundação para a Ciência e a Tecnologia, Portugal

Agência Nacional de Cultura Científica, Portugal

Jury of academic degree

Topic
Role		 Candidate name (Type of degree)
Institution / Organization
2021/02/26 Hydrogels derived from human chorionic membrane as an innovative platform for 3D cell culture
Supervisor
 Elisa Alexandra Gonçalves Martins (Master)
Universidade de Aveiro, Portugal
2021/02/25 Taking advantage of 3D humanized in vitro models to study pulmonary diseases
Supervisor
 Francisca Rodrigues da Piedade (Master)
Universidade de Aveiro, Portugal
2021/02/19 Removal of albumin from platelet lysates for the fabrication of hydrogels for 3D cell culture
Supervisor
 Ana Miguel da Silva Loureiro (Master)
Universidade de Aveiro, Portugal
2019/07/16 Hidrogéis bioativos com superfície micropadronizada
(Thesis) Main arguer
 Pedro Cruz Ribeiro Vilares (Master)
Universidade de Aveiro Departamento de Física, Portugal
2018/07 Physicochemical characterization of a bioactive and bioadhesive nanocomposite hydrogel
(Thesis) Main arguer
 Raquel Maria da Costa Gonçalves (Other)
Universidade de Aveiro Departamento de Química, Portugal
2017/12 Platelet lysates loaded laminarin microparticles for cell attachment and expansion
Supervisor
 Cláudia Isabel Rodrigues Martins (Master)
Universidade de Aveiro Departamento de Química, Portugal
2016 Enzymatic degradation of natural polysacharide-based layer-by-layer devices
(Thesis) Main arguer
 Matias Joaquin Cardoso (Master)
Universidade do Minho, Portugal

Association member

Society Organization name Role
2022/02 - Current Sociedade Portuguesa de Diabetologia (SPD)
2021/10 - Current Tissue Engineering and Regenerative Medicine International Society, Inc. (TERMIS)
2018/07 - Current European Association for Cancer Research - EACR
2016/01 - Current Sociedade Portuguesa de Química
2016 - 2018 Young Chemists Group - SPQ Board Member

Committee member

Activity description
Role		 Institution / Organization
2022/05 - Current European Female Founders The European Female Founders is on a mission to inspire, encourage and build a new path for female founders.
Member

Conference scientific committee

Conference name Conference host
2016/03 - 2016/06 5th Portuguese Young Chemists Meeting (5th PYCheM) and 1st European Young Chemists Meeting (1st EYCheM), April 2016 - Guimarães, Portugal. Guimarães

Consulting

Activity description Institution / Organization
2017/01 - 2019/06 Preparation of a proposal for a new PhD Program in Biotechnology at University of Aveiro (2017). The proposal was approved in 2018 by the A3ES- Agência de Avaliação e Acreditação do Ensino Superior. Universidade de Aveiro, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2021/03 - Current Laboratório Q1 (Licenciatura) Universidade de Aveiro, Portugal

Universidade de Aveiro Departamento de Química, Portugal
2020/01/09 - Current Biochemistry and Biophysics Licenciatura em Enfermagem (Licenciatura) Universidade de Aveiro, Portugal

Universidade de Aveiro Departamento de Química, Portugal
2019/10/31 - Current Natural-based hydrogels in bioengineering (Outros) Universidade de Aveiro Departamento de Química, Portugal
2019/10 - 2019/10 Processing of Biomaterials - Hydrogels 3rd Training School on Bioinspired Adhesive Hydrogels and Polymers - ENBA (Outros) Universidade de Aveiro CICECO, Portugal

Universidade de Aveiro Departamento de Química, Portugal
2017 - 2018 Cells and Tissue Engineering: Advanced hydrogel technologies to address key challenges in tissue engineering Master in Biotechnology (Mestrado integrado) Universidade de Aveiro Departamento de Química, Portugal
2016 - 2017 Cells and Tissue Engineering: Engineering complex hydrogels and microfabrication Master in Biotechnology (Mestrado integrado) Universidade de Aveiro Departamento de Química, Portugal
2016 - 2017 Macromolecular Chemistry Master in Biotechnology (Mestrado) Universidade de Aveiro Departamento de Química, Portugal

Evaluation committee

Activity description
Role		 Institution / Organization Funding entity
2020/10/16 - Current Latvian Council of Science-ACT ON COMMISSIONING OF THE WORK
Evaluator
 Latvijas Zinatnes Padome, Latvia
2021/11/04 - 2021/12 Evaluation of the Marie Sklodowska-Curie Postdoctoral Fellowships (PF) 2021 Call proposals.
Evaluator
 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions, Belgium

European Commission Marie Sklodowska-Curie Actions, Belgium		 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions

Journal scientific committee

Journal title (ISSN) Publisher
2021/04 - Current Materials Today Communications (2352-4928) Elsevier
2020/12 - Current Advanced NanoBiomed Research (2699-9307) John Wiley & Sons
2020 - Current Tissue Engineering (1076-3279) Mary Ann Liebert
2018/07 - Current Biotechnology Progress (1520-6033) John Wiley & Sons
2018/06 - Current Nanomaterials (2079-4991) MDPI
2017/01 - Current ACS Biomaterials Science & Engineering (2373-9878) American Chemical Society
2017 - Current Applied Surface Science (0169-4332) Elsevier
2017 - Current Gels (2310-2861) MDPI AG
2016/09 - Current Acta Biomaterialia (1742-7061) Elsevier

Other jury / evaluation

Activity description Institution / Organization
2019/09 - 2019/09 Monography evaluation: "Liquefied capsules containing nanogrooved microdiscs and co-encapsulated endothelial and mesenchymal stem cells for bone tissue engineering”, Master student in Biotechnology, Mariana da Silva Carreira. Universidade de Aveiro Departamento de Química, Portugal
2019/07 - 2019/07 Monography evaluation: "Development of Advanced Decellularized-Matrix Based Breast Cancer 3D In Vitro Models for Immunotherapeutic Screening" - Luís Pedro Correia Pinto Ferreira, Master student in Biochemistry. Universidade de Aveiro Departamento de Química, Portugal
Distinctions

Award

2022 Women TechEU Supporting deep-tech start-ups led by women
European Innovation Council, Belgium
2020 Bluepharma | University of Coimbra Innovation Award 2019
Bluepharma, Portugal

Universidade de Coimbra, Portugal
2018 Empreende + "Technological Entrepreneurship"
NOE – Noroeste Empreendedor and Unidade de Transferência de Tecnologia (UATEC), Portugal
2017 PROT IERA - contest for the materialization of business ideas
2012 Young Investigator Travel Award - 3rd TERMIS World Congress
TERMIS-SYIS - Tissue Engineering and Regenerative Medicine International Society, Austria
2011 Best Student Poster Prize - The Biointerphases Second Prize for the Best Student Poster at the European Congress and Exhibition on Advanced Materials and Processes

Other distinction

2025 Recognized in Ciência Viva's "Mulheres na Ciência" initiative (5th volume, 2025), featuring over 100 Portuguese women scientists for contributions to biotechnology and tissue engineering.
Ciência Viva, Portugal
2024 Shortlisted for the Lush Prize 2024
LUSH Glasgow City, United Kingdom
2022 Selected to participate in this edition of HiTech 2022
HiSeedTech, Portugal
2021 Finalist of the Amyris Innovation BIG Impact Award
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

Amyris Inc, United States
2020 Assistant Researcher (Stimulus of Scientific Employment, Individual Support (CEECIND) - 3rd Edition)
Fundação para a Ciência e a Tecnologia, Portugal
2013 Registration Awards - 8th International Annual Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)
Portuguese Society for Stem Cells and Cell Therapies-SPCE-TC, Portugal