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Main research lines: 1) Biology of fat deposition: Paula Alexandra Lopes is a lipid researcher whose career aims at identifying mechanism-based molecular targets for obesity therapeutic intervention using disease models (e.g. genetic and diet-induced), genomics and DNA-based approaches for lipid metabolism regulation and inflammation. The main focus stands on cellular and molecular mechanisms that regulate adipose cell fate, extending our mechanistic evaluation of biological systems from cellular to organism levels. The ultimate goal is to control gene expression and signaling networks involved in adipocytes (trans) differentiation and proliferation, based on genetic susceptibilities and cellular contexts, and to exploit novel therapeutic strategies to counteract obesity and associated metabolic complications, in particular insulin resistance and diabetes. 2) Development of nutritional strategies and bioactive lipids from animal origin: A related research line of Paula A. Lopes is on the development of nutritional strategies and bioactive lipids from animal origin, including fat-soluble antioxidant vitamins, n-3 polyunsaturated fatty acids, in particular eicosapentaenoic (EPA, 20:5n-3) and docosahexaenoic (DHA, 22:6n-3), and conjugated linoleic acid (CLA) isomers, that could reduce adiposity and inflammation or improve body fat partitioning and therefore, impact positively on consumers’ health. 3) Oxidative stress in health and disease: At the beginning of her career, Paula A. Lopes studied oxidative stress markers (antioxidant defense and oxidative injury) in healthy humans under the influence of age, sex, hormonal status for women and risk factors (e.g. dyslipidemia, hypertension and smoking) or having diagnosed atherosclerosis. A minor participation in ecotoxicology was achieved during her graduation period in which she studied redox balance markers in micromammals and fishes as sentinels of exposure to heavy metals contamination and derived oxidative stress.
Identification

Personal identification

Full name
Paula Alexandra Lopes

Citation names

  • Lopes, Paula Alexandra

Author identifiers

Ciência ID
0912-38D0-9D20
ORCID iD
0000-0002-6755-4572

Email addresses

  • ampalopes@fmv.ulisboa.pt (Professional)

Telephones

Fax
  • 213652829 (Professional)
Telephone
  • 213652832 (Professional)

Addresses

  • Faculdade de Medicina Veterinária, ULisboa. Avenida da Universidade Técnica, Pólo Universitário do Alto da Ajuda, Secção de Bioquímica, Gabinete C4.68, 1300-477 , Lisboa, Lisboa, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2006
Concluded
PhD (Doutoramento)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Redox balance and risk factors associated with atherogenesis in humans" (THESIS/DISSERTATION)
Approved with distinction and praise (unanimity)
1997
Concluded
Biologia Aplicada aos Recursos Animais - Variante de Recursos Terrestres (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Searching for biochemical markers of heavy metals in fish and wild mouse from Guadiana river" (THESIS/DISSERTATION)
16 graduation (19 for final thesis)
Affiliation

Science

Category
Host institution
Employer
2019/02/01 - 2025/04/30 Contracted Researcher (Research) Universidade de Lisboa - Faculdade de Medicina Veterinária, Portugal
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal

Others

Category
Host institution
Employer
2016/07/01 - 2019/01/31 Pós-Doc Fellowship (Portugal 2020, ref.: 08/SI/3399/2015) Universidade de Lisboa - Faculdade de Medicina Veterinária, Portugal
2016/02/01 - 2016/04/30 Pós-Doc Fellowship (FCT, ref.: UID/CVT/00276/2013 project) Universidade de Lisboa - Faculdade de Medicina Veterinária, Portugal
2014/12/03 - 2015/09/02 Post-Doc Fellowship (Projeto de Investigação Incentivo referência, FCT/Incentivo/AGR/UI0276/2014) Universidade Técnica de Lisboa - Faculdade de Medicina Veterinária, Portugal
2009/07/01 - 2014/06/30 Assistant Investigator - "Science 2008" from FCT Universidade Técnica de Lisboa - Faculdade de Medicina Veterinária, Portugal
Universidade Técnica de Lisboa - Faculdade de Medicina Veterinária, Portugal
2006/06/01 - 2009/06/30 Post-Doc Fellowship (FCT/SFRH/BPD/23931/2005) Universidade Técnica de Lisboa - Faculdade de Medicina Veterinária, Portugal
2000/04/01 - 2004/03/31 PhD Fellowship (FCT/PRAXIS XXI/BD/21444/1999) Universidade de Lisboa Faculdade de Ciências, Portugal
1998/01/01 - 1999/12/31 Technical Research Fellowship (FCT/PRAXIS XXI/BTI/14486/1997) Universidade de Lisboa Faculdade de Ciências, Portugal
1996/09/01 - 1997/11/20 Training period of Graduation in Biology (Fellowship PRODEP/1996) Universidade de Lisboa Faculdade de Ciências, Portugal
Projects

Contract

Designation Funders
2018 - Current Disclosing the potential of seaweeds for feeding pigs and poultry
PTDC/CAL-ZOO/30238/2017
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
Ongoing
2018 - Current Exploring the potential of bioactive nutrients for the prevention of Alzheimer’s disease and cognitive aging through in vitro assays, in vivo verification, and in silico quantification of health benefits
PTDC/SAU-NUT/30455/2017
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
Ongoing
2023/03/01 - 2024/08/31 Estudo piloto sobre lípidos estruturados e por medida: novas estratégias sustentáveis em ácido docosahexaenóico (DHA) para a prevenção da doença de Alzheimer
2022.08133.PTDC
Principal investigator
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal

Instituto Português do Mar e da Atmosfera, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/08 - 2021/10/30 Impact of LPS-induced chronic inflammation on aquaporins expression in piglets
CIISA 2020 INOV - 17
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Ongoing
2018/05/07 - 2019/05/31 Characterization of transmembrane protein channels in the small intestine of piglets fed on amino acids enriched diets: a translational model to humans
2017 INOV - 17
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Concluded
2016 - 2019 Valorização das microalgas para a produção de suínos e melhoria da qualidade da sua carne com base numa nova geração de enzimas comerciais
Portugal2020, 08/SI/3399/2015
Post-doc Fellow
Concluded
2015 - 2019 Developing novel feed enzymes for improving the nutritional value of microalgae for monogastrics
FCT/PTDC/CVT-NUT/5931/2014
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
Concluded
2015 - 2019 Developing novel feed enzymes for improving the nutritional value of microalgae for monogastrics
FCT/PTDC/CVT-NUT/5931/2014
N/A
2017/01/01 - 2017/12/31 Modulation of aquaporins gene expression by n-3 polyunsaturated fatty acids (PUFA) lipid structures in white and brown adipose tissue from hamsters
2016 INOV - 20
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Concluded
2013/03/01 - 2016 MODULATION OF RUMEN BIOHYDROGENATION THROUGH POLYUNSATURATED FATTY ACID OVERLOAD AND TANNINS
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBD2%F904682%F2012/PT
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2012 - 2014 Lípidos estructurados: nuevas estrategias de diseño y mejora de la salud
AGL2011-25807
Researcher
Governo Espanhol, Ministerio de Ciencia e Innovación, Spain
Concluded
2011/01/01 - 2013/12/31 Changes in muscle gene expression as response to selection for high growth and to growth path
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
Fundação para a Ciência e a Tecnologia
2010/03/01 - 2013/11/30 Improving fat partioning and nutritional quality in pigs: developing feeding strategies and providing insights into genetic and metabolic mechanisms
Fundação para a Ciência e a Tecnologia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/10/01 - 2011 An integrated study of lipid composition and its genetic regulation in bovine meats with Protected Designation of Origin (PDO)
Fundação para a Ciência e a Tecnologia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007 - 2009 Rationale and options in dietary use of canned sardines in olive oil and tomato (omega 3, lycopene, and oleic acid) related to inflammatory and atherotrombogenic biomarkers in obesity and metabolic syndrome related cardiovascular disease
FCT/PTDC/SAU-OSM/70560/2006
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
Concluded
2003 - 2005 Biological effects of dietetic and supplemented conjugated linoleic acid (CLA) isomers in the Portuguese population
FCT/POCTI/CVT/44750/2002
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
Concluded
2002 - 2004 Markers of the pro-oxidant/antioxidant balance and characterization of the allelic profile of apolipoprotein E in inhabitants of Lisbon and Ponta Delgada
FCT/POCTI/ESP/41008/2001
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
Concluded
2002 - 2004 An assessment of lead exposure in small mammals from an abandoned mine area in the center of Portugal)
FCT/POCTI/39917/BSE/2001
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
Concluded
1997 - 1999 Blood parameters associated with antioxidant function in Portuguese populations
FCT/PRAXIS XXI/PSAU/0066/1996
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
Concluded
1996 - 1998 Research on biochemical parameters indicative of toxicity in aquatic and terrestrial communities exposed to heavy metals from Guadiana river basin
PEAM/O/NMA/666/1995
Researcher
Ministério do Ambiente, Portugal
Concluded
Outputs

Publications

Book
  1. Martins, S.V.; Alfaia, C.M.; Lopes, P.A.; Prates, J.M.. Dietary sources and health implications of arachidonic acid. 2014.
  2. Lopes, P.A.; Martins, S.V.; Prates, J.A.M.. Modulation of dietary conjugated linoleic acid (CLA) effects by saturated fats. 2011.
  3. Alfaia, C.M.; Martins, S.V.; Lopes, P.A.; Mestre Prates, J.A.. Conjugated linoleic acid (CLA) as a body fat reducing agent. 2011.
Book chapter
  1. Microalgae application in feeds for monogastrics. "Microalgae application in feeds for monogastrics". In Handbook of food and feed from microalgae: production, application, regulation, and sustainability, edited by Eduardo Jacob-Lopes, Maria Isabel Queiroz, Mariana Manzoni Maroneze, Leila Queiroz Zepka, 411-420. Elsevier Science, 2023.
    Published
  2. Lopes, Paula Alexandra. "Ameliorating pork marbling and quality with novel feeding approaches". In A Portrait of the State-of-the-Art Research at CIISA. Elsevier, 2020.
    Accepted
  3. Lopes, Paula A.; Pestana, José M.; Coelho, Diogo; Madeira, Marta S.; Alfaia, Cristina M.; Prates, José A.M.. "From Natural Triacylglycerols to Novel Structured Lipids Containing n-3 Long-Chain Polyunsaturated Fatty Acids". In The Molecular Nutrition of Fats, 225-235. Elsevier, 2019.
    10.1016/b978-0-12-811297-7.00017-2
  4. Alfaia, C.M.; Lopes, P.A.; Madeira, M.S.; Pestana, J.M.; Coelho, D.; Toldrá, Fidel; Prates, J.A.M.. "Current feeding strategies to improve pork intramuscular fat content and its nutritional quality". In Advances in Food and Nutrition Research, 53-94. Elsevier, 2019.
    10.1016/bs.afnr.2019.03.006
  5. Alfaia, Cristina Mateus; Madeira, Marta S.; Pestana, José; Coelho, Diogo; Lopes, Paula A.; Toldrá, Fidel; Prates, José A.M.. "Pork by-products". In Byproducts from Agriculture and Fisheries: Adding Value for Food, Feed, Pharma and Fuels, 19-41. New Jersey: John Wiley & Sons, Ltd, 2019.
    10.1002/9781119383956.ch2
  6. Lopes, Paula Alexandra. "Effect of glutamine and/or cystine on gut health, immunity and redox status in post-weaning piglets". In Energy and protein metabolism and nutrition, 307-308. Wageningen Academic Publishers, 2019.
  7. Lopes, Paula Alexandra. "Dietary Sources and Health Implications of Arachidonic Acid". In Arachidonic Acid - Sources, Biosynthesis and Health Effects, 29-82. New York, United States: Nova Science Publishers Inc, 2014.
  8. Lopes, Paula Alexandra. "Modulation of Dietary Conjugated Linoleic Acid (CLA) Effects by Saturated Fats". In Saturated Fats: Metabolism, Disease Risks and Public Awareness, 45-70. New York, United States: Nova Science Publishers Inc., 2012.
  9. Lopes, Paula Alexandra. "Conjugated Linoleic Acid (CLA) as a Body Fat Reducing Agent". In Body Fat: Composition, Measurements and Reduction Procedures. New York, United States: Nova Science Publishers Inc., 2011.
    10.1007/978-3-540-47648-1_1313
  10. Lopes, Paula Alexandra. "Estado del Se, Cu y Zn y su relación com el perfil lipídico sérico en sujetos portugueses de Lisboa y el Archipiélago de las Azores". In Elementos Traza y Metabolismo Lipídico, 171-185. Madrid, Spain: Editorial MAPFRE, 2004.
Conference paper
  1. Lopes, Paula Alexandra. "Dietary trans fatty acids correlated negatively with estimation activity of stearoyl-CoA desaturase". Paper presented in 12th Meeting on Food Chemistry - Chemistry and Structure, Lisboa, 2014.
    Published
  2. Lopes, Paula Alexandra. "Effect of breed and dietary protein and lysine levels on pork quality traits". Paper presented in 57th ICoMST, International Congress of Meat Science and Technology, Ghent, 2011.
    Published
  3. Lopes, Paula Alexandra. "Meat quality and sensory attributes of two Portuguese bovine breeds, Alentejana and Barrosã, under distinct feeding regimens". Paper presented in 57th ICoMST, International Congress of Meat Science and Technology, Ghent, 2011.
    Published
  4. Lopes, Paula Alexandra. "Differential cellularity and fatty acid profile in subcutaneous and mesenteric fat depots from Portuguese bovine breeds". Paper presented in 57th ICoMST, International Congress of Meat Science and Technology, Ghent, 2011.
    Published
  5. Lopes, Paula Alexandra. "Blood elemental levels and antioxidant markers in humans with atherosclerotic disease". Paper presented in Proceedings of 4th International Symposium on Trace Elements in Human: new perspectives, Atenas, 2003.
    Published
  6. Lopes, Paula Alexandra. "A comparative study of blood antioxidant parameters in two Portuguese urban populations.". Paper presented in Trace Elements in Man and Animals, Evian Les Bains, 1999.
    Published
Conference poster
  1. "Different dietary n-3 polyunsaturated fatty acid formulations distinctively modify fatty acid and N-acylethanolamine profiles in rat brain". Paper presented in American Society for Nutrition (ASN), 2021.
  2. Lopes, Paula Alexandra. "Docosahexaenoic acid at the sn-2 position of structured triacylglycerols improves n-3 polyunsaturated fatty acid assimilation in tissues of hamsters". Paper presented in 17th Euro Fed Lipid Congress and Expo, 2019.
  3. Lopes, Paula Alexandra. "Antioxidant potential of Arthrospira platensis as feed ingredient, individually or combined with exogenous enzymes, in piglets’ muscle". Paper presented in 17th Euro Fed Lipid Congress and Expo, 2019.
  4. Lopes, Paula Alexandra. "Degradation of the recalcitrant cell wall of Chlorella vulgaris by enzymatic method". Paper presented in AlgaEurope 2019, 2019.
  5. Lopes, Paula Alexandra. "Docosahexaenoic acid (DHA) at the sn-2 position of triacylglycerols increases DHA incorporation in brown, but not in white adipose tissue, of hamsters". Paper presented in 16th Euro Fed Lipid Congress and Expo, 2018.
  6. Lopes, Paula Alexandra. "Restriction of dietary protein does not promote hepatic lipogenesis in lean or fatty pigs". Paper presented in 16th Euro Fed Lipid Congress and Expo, 2018.
  7. Lopes, Paula Alexandra. "Novel combination of feed enzymes to improve the degradation of Chlorella vulgaris recalcitrant cell wall". Paper presented in 16th Euro Fed Lipid Congress and Expo, 2018.
  8. Lopes, Paula Alexandra. "Two CAZymes constituted mixture to improve the degradation of Arthrospira platensis cell wall". Paper presented in 16th Euro Fed Lipid Congress and Expo, 2018.
  9. Lopes, Paula Alexandra. "Modulation of aquaporins gene expression by n-3 long-chain polyunsaturated fatty acids (LCPUFA) lipid structures in white and brown adipose tissue from hamsters". Paper presented in CIISA Congress 2018 - Exploring the boundaries of animal, veterinary and biomedical sciences, 2018.
  10. Lopes, Paula Alexandra. "The effect of Arthrospira sp. microalga as a feed supplement on growth performance, pigmentation and meat quality in broiler chickens". Paper presented in CIISA Congress 2018 - Exploring the boundaries of animal, veterinary and biomedical sciences, 2018.
  11. Lopes, Paula Alexandra. "A high-throughput approach to assess microalgae cell wall disruption by enzymatic digestion". Paper presented in CIISA Congress 2018 - Exploring the boundaries of animal, veterinary and biomedical sciences, 2018.
  12. Lopes, Paula Alexandra. "Effet du rapport valine:lysine sur les performances de croissance et le métabolisme des acides aminés à chaîne ramifiée des porcelet". Paper presented in Journées de la Recherche Porcine 2017, 2017.
  13. Lopes, Paula Alexandra. "The combination of arginine and leucine supplementation of reduced crude protein diets in pigs improves meat eating quality". Paper presented in 61th International Congress of Meat Science and Technology, INRA, 2015.
  14. Lopes, Paula Alexandra. "The combination of arginine and leucine supplementation of reduced crude protein diets in pigs increases meat eating quality". Paper presented in VIth Congresso da Sociedade Portuguesa de Ciências Veterinárias, 2014.
  15. Lopes, Paula Alexandra. "Multiple regression analysis for prediction of beef intramuscular fat and its fatty acid composition from red blood cell fatty acids". Paper presented in VIth Congresso da Sociedade Portuguesa de Ciências Veterinárias, 2014.
  16. Lopes, Paula Alexandra. "ALA, EPA and DHA supplementation alters brain structure?". Paper presented in 12th Euro Fed Lipid Congress, 2014.
  17. Lopes, Paula Alexandra. "Effects of different n-3/n-6 PUFA-enriched diets on the fatty acid profile of visceral fat of hamster". Paper presented in 12th Euro Fed Lipid Congress, 2014.
  18. Lopes, Paula Alexandra. "Lipid composition and nutritional quality of intramuscular fat in organic beef". Paper presented in XI Congresso de Nutrição e Alimentação, 2012.
  19. Lopes, Paula Alexandra. "Is the t8,c10 conjugated linoleic acid isomer a new anti-adipogenic compound?". Paper presented in 10th Euro Fed Lipid Congress, 2012.
  20. Lopes, Paula Alexandra. "Effect of reduced protein diets on fatty acid composition in the subcutaneous adipose tissue of two pig genotypes". Paper presented in 10th Euro Fed Lipid Congress, 2012.
  21. Lopes, Paula Alexandra. "Meat quality and sensory attributes of two Portuguese bovine breeds, Alentejana and Barrosã, under distinct feeding regimens". Paper presented in 57th ICoMST, International Congress of Meat Science and Technology, 2011.
  22. Lopes, Paula Alexandra. "Effect of breed and dietary protein and lysine levels on pork quality traits". Paper presented in 57th ICoMST, International Congress of Meat Science and Technology, 2011.
  23. Lopes, Paula Alexandra. "The unsaturation degree of neutral lipids is influenced by CLA supplementation contrarily to polar lipids". Paper presented in 9th Euro Fed Lipid Congress, 2011.
  24. Lopes, Paula Alexandra. "Ovine fat naturally enriched in CLA comparing to synthetic CLA promotes a higher deposition of the c9,t11 isomer in liver and muscle". Paper presented in 9th Euro Fed Lipid Congress, 2011.
  25. Lopes, Paula Alexandra. "Fish-based diet improves cardiometabolic biomarkers of normo- and isocaloric meals in healthy Wistar rats: implications to obesity-related comorbidities". Paper presented in XI International Congress on Obesity, 2010.
  26. Lopes, Paula Alexandra. "Effects of a standard ómega-3 supplemented diet in Wistar rats. Is there room for improvements or not?". Paper presented in II World Congress of Public Health Nutrition, 2010.
  27. Lopes, Paula Alexandra. "Effect of propylene glycol and linseed oil supplementation on intramuscular fatty acids of lamb meat". Paper presented in International Conference on Food Innovation-Food Innova 2010, 2010.
  28. Lopes, Paula Alexandra. "Diet supplementation with conjugated linoleic acid impairs permeability and fluidity of adipose plasma membranes from obese Zucker rats". Paper presented in 8th Euro Fed Lipid Congress, 2010.
  29. Lopes, Paula Alexandra. "Antioxidant markers and cardiovascular risk factors in Azorean subjects with coronary artery disease". Paper presented in 14th World Congress on Heart Disease, International Academy of Cardiology, 2008.
  30. Lopes, Paula Alexandra. "Citokine profile in Zucker rats fed CLA and saturated fat diets". Paper presented in XVI National Congress of Biochemistry, 2008.
  31. Lopes, Paula Alexandra. "Apoptotic responses in Zucker rats supplemented with CLA under different fat-based diets". Paper presented in XVI National Congress of Biochemistry, 2008.
  32. Lopes, Paula Alexandra. "Blood antioxidant markers and elemental levels in Azorean patients with coronary artery disease – a preliminary study". Paper presented in VIIIth Conference of the International Society for Trace Element Research in Humans (ISTERH), IXth Conference of the Nordic Trace Element Society (NTES) and VIth Conference of the Helenic Trace Element Society (HTES), 2007.
  33. Lopes, Paula Alexandra. "Blood trace element levels in patients with stabilized atherosclerosis". Paper presented in VIIIth Conference of the International Society for Trace Element Research in Humans (ISTERH), IXth Conference of the Nordic Trace Element Society (NTES) and VIth Conference of the Helenic Trace Element Society (HTES), 2007.
  34. Lopes, Paula Alexandra. "CLA: Teores em Alimentos Comerciais e Estimativa de Consumo pela População Portuguesa". Paper presented in I Feira do Conhecimento e Inovação, 2006.
  35. Lopes, Paula Alexandra; Bettencourt, Conceico; Montiel, Rafael; Santos, Cristina; Pavão, Maria Leonor; Viegas-Crespo, Ana Maria; Lopes, Paula Alexandra; Lima, Manuela. "Polymorphism of the Apo E locus in the Azores Islands (Portugal)". Paper presented in European Human Genetics Conference 2006 in Conjunction with the European Meeting on Psychosocial Aspects of Genetics, 2006.
    10.1353/hub.2006.0053
  36. Lopes, Paula Alexandra. "Health value of fat in Portuguese butters". Paper presented in I Encontro Nacional de Bromatologia, Hidrologia e Toxicologia, 2006.
  37. Lopes, Paula Alexandra. "Evaluation of blood elemental levels and genetics of apo E in high risk and atherosclerotic subjects". Paper presented in TEMA 12, Trace Elements in Man and Animals, 2005.
  38. Lopes, Paula Alexandra. "Redox balance and blood elemental levels in atherosclerosis". Paper presented in 17th International Conference on Ion Beam Analysis, 2005.
  39. Lopes, Paula Alexandra. "Reference values of some trace elements in blood for human biomonitoring in pathological conditions". Paper presented in European Conference on X-Ray Spectrometry (EXRS 2004), 2004.
  40. Lopes, Paula Alexandra. "Blood antioxidant markers in Azorean subjects with coronary heart disease". Paper presented in 2nd Spanish and Portuguese Congress on Free Radicals, 2004.
  41. Lopes, Paula Alexandra. "Trace element levels and redox markers in human atherosclerosis: relationship with apo E polymorphism". Paper presented in Society for Trace Element Research in Humans (ISTERH), 7th International Conference, 2004.
  42. Lopes, Paula Alexandra. "Preliminary report on redox balance and blood elemental levels in atherosclerosis: relationship with apo E polymorphism". Paper presented in XIV Congresso Nacional de Bioquímica, 2004.
  43. Lopes, Paula Alexandra. "Biological effects of metal contaminants on Algerian mice (Mus spretus) inhabiting old mine sites in central Portugal". Paper presented in CICTA 2003, 5th Iberian and 2nd Iberoamerican Congress of Environmental Contamination and Toxicology, 2003.
  44. Lopes, Paula Alexandra. "Blood elemental levels and antioxidant markers in humans with atherosclerotic disease". Paper presented in 4th International Symposium on Trace Elements in Human: New Perspectives, 2003.
  45. Lopes, Paula Alexandra. "Evaluation of extracellular serum antioxidants in healthy subjects from Lisbon". Paper presented in 3rd International Meeting, Advances in Trace Elements, Minerals & Vitamins in Humans, 2002.
  46. Lopes, Paula Alexandra. "Trace element levels in freshwater fish (Leuciscus alburnoides complex) and in field mice (Mus spretus) from a mine area". Paper presented in 11th International Symposium on Trace Elements in Man and Animals, 2002.
  47. Lopes, Paula Alexandra. "Serum trace element levels (Cu, Zn, Se) in a sample of the human population of Lisbon". Paper presented in 11th International Symposium on Trace Elements in Man and Animals, 2002.
  48. Lopes, Paula Alexandra. "Morphophysiological and biochemical results of lead intoxication in Algerian mice (Mus spretus Lataste, 1883)". Paper presented in 1st FESTEM Congress on Trace Elements and Minerals in Medicine and Biology, 2001.
  49. Lopes, Paula Alexandra. "SOD and GST as biomarkers of toxicity in freshwater fish (Leuciscus alburnoides complex) and field mice (Mus spretus) exposed to inorganic pollutants". Paper presented in Conferência Biomarkers´2001, 2001.
  50. Lopes, Paula Alexandra. "Estudo da variabilidade de elementos minerais e da actividade do glutationo S-transferase em Mus spretus expostos a concentrações elevadas de manganês e de selénio". Paper presented in 3º Congresso Ibérico de Contaminação e Toxicologia Ambiental – CICTA 2000, 2000.
  51. Lopes, Paula Alexandra. "Capacidade bioindicadora dos anfíbios face à dos peixes e mamíferos ripícolas expostos a metais pesados (rio Oeiras/Minas de Neves-Corvo". Paper presented in VI Congreso Luso-Español – X Congreso Español de Herpetología, 2000.
  52. Lopes, Paula Alexandra. "Pro-oxidant/antioxidant profile of two Portuguese urban populations – a comparative study". Paper presented in XII Congresso Nacional de Bioquímica, 2000.
  53. Lopes, Paula Alexandra. "Preliminary results regarding the pro-oxidant/antioxidant profile of the urban population of Lisbon – Portugal". Paper presented in 16th LIAC Meeting – 7th Meeting on Lipid Metabolism and Related Pathology, 2000.
  54. Lopes, Paula Alexandra. "A comparative study of blood antioxidant parameters in two Portuguese urban populations". Paper presented in 10th International Symposium on Trace Elements in Man and Animal, 1999.
  55. Lopes, Paula Alexandra. "Research on biochemical parameters indicative of toxicity in Mus spretus exposed to heavy metals". Paper presented in Euro-American Mammal Congress, 1998.
Journal article
  1. Spínola, Maria P.; Alfaia, Cristina M.; Costa, Mónica M.; Pinto, Rui M. A.; Lopes, Paula Alexandra; Pestana, José M.; Tavares, João C.; et al. "Impact of high Spirulina diet, extruded or supplemented with enzymes, on blood cells, systemic metabolites, and hepatic lipid and mineral profiles of broiler chickens". Frontiers in Veterinary Science 11 (2024): 1342310. http://dx.doi.org/10.3389/fvets.2024.1342310.
    Published • 10.3389/fvets.2024.1342310
  2. Pádua, Mafalda Soares; Guil-Guerrero, José L.; Prates, José A. M.; Lopes, Paula Alexandra. "Insights on the Use of Transgenic Mice Models in Alzheimer’s Disease Research". International Journal of Molecular Sciences 25 5 (2024): 2805. http://dx.doi.org/10.3390/ijms25052805.
    Open access • Published • 10.3390/ijms25052805
  3. Lopes, Paula; Alfaia, Cristina; Pestana, José; Prates, José. "Structured Lipids Engineering for Health: Novel Formulations Enriched in n-3 Long-Chain Polyunsaturated Fatty Acids with Potential Nutritional Benefits". Metabolites 13 10 (2023): 1060. http://dx.doi.org/10.3390/metabo13101060.
    Open access • Published • 10.3390/metabo13101060
  4. Lopes, Paula A.; Fonseca, Elisabete; da Silva, Inês V.; Vigia, Emanuel; Paulino, Jorge; Soveral, Graça. "Aquaporins Transcripts with Potential Prognostic Value in Pancreatic Cancer". Genes 14 9 (2023): 1694. http://dx.doi.org/10.3390/genes14091694.
    Open access • Published • 10.3390/genes14091694
  5. Silva, Inês V. da; Coelho, Diogo; Prates, José António Mestre; Soveral, Graça; Lopes, Paula A.. "Tissue-Specific Variation in Aquaporins and Cytokines Transcriptional Profiles in Piglets being LPS Challenged". Frontiers in Bioscience-Landmark 28 6 (2023): 126. http://dx.doi.org/10.31083/j.fbl2806126.
    Open access • Published • 10.31083/j.fbl2806126
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  7. Ribeiro, David M.; Pinto, Rui M. A.; Lopes, Paula A.; Pestana, José M.; Alfaia, Cristina M.; Costa, Mónica M.; Carvalho, Daniela F. P.; et al. "Effect of Laminaria digitata dietary inclusion and CAZyme supplementation on blood cells, serum metabolites and hepatic lipids and minerals of weaned piglets". Scientific Reports 13 1 (2023): 6598. http://dx.doi.org/10.1038/s41598-023-33835-3.
    Open access • Published • 10.1038/s41598-023-33835-3
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    Open access • Published • 10.3390/molecules27217425
  9. Martins, Cátia F.; Lopes, Paula A.; Palma, Mariana; Pinto, Rui M. A.; Costa, Mónica; Alfaia, Cristina M.; Pestana, José M.; et al. "Impact of dietary Chlorella vulgaris and feed enzymes on health status, immune response and liver metabolites in weaned piglets". Scientific Reports 12 1 (2022): 16816. http://dx.doi.org/10.1038/s41598-022-21238-9.
    Open access • Published • 10.1038/s41598-022-21238-9
  10. Alfaia, Cristina M.; Costa, Mónica M.; Lopes, Paula A.; Pestana, José M.; Prates, José A. M.. "Use of Grape By-Products to Enhance Meat Quality and Nutritional Value in Monogastrics". Foods 11 18 (2022): 2754. http://dx.doi.org/10.3390/foods11182754.
    Open access • Published • 10.3390/foods11182754
  11. Costa, Mónica M.; Alfaia, Cristina M.; Lopes, Paula A.; Pestana, José M.; Prates, José A. M.. "Grape By-Products as Feedstuff for Pig and Poultry Production". Animals 12 17 (2022): 2239. http://dx.doi.org/10.3390/ani12172239.
    Open access • Published • 10.3390/ani12172239
  12. Lopes, Paula; Coelho, Diogo; Prates, José. "Testimony on a Successful Lab Protocol to Disrupt Chlorella vulgaris Microalga Cell Wall". Current Developments in Nutrition 6 (2022): 1146. http://dx.doi.org/10.1093/cdn/nzac072.018.
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  13. Lopes, Paula A.; Coelho, Diogo; Prates, José A. M.. "Testimony on a successful lab protocol to disrupt Chlorella vulgaris microalga cell wall". PLOS ONE 17 5 (2022): e0268565. http://dx.doi.org/10.1371/journal.pone.0268565.
    Published • 10.1371/journal.pone.0268565
  14. Costa, Mónica Mendes; Lopes, Paula Alexandra; Assunção, José Miguel Pestana; Alfaia, Cristina Maria Riscado Pereira Mate; Coelho, Diogo Francisco Maurício; Mourato, Miguel Pedro; Pinto, Rui Manuel Amaro; Lordelo, Maria Madalena; Prates, José António Mestre. "Combined effects of dietary Laminaria digitata with alginate lyase on plasma metabolites and hepatic lipid, pigment and mineral composition of broilers". BMC Veterinary Research 18 1 (2022): 153.. http://dx.doi.org/10.1186/s12917-022-03250-3.
    Published • 10.1186/s12917-022-03250-3
  15. "Impact of Chlorella vulgaris as feed ingredient and carbohydrases on the health status and hepatic lipid metabolism of finishing pigs.". Research in Veterinary Science 144 (2022): 44-53.
    Open access • Published
  16. dos Santos Madeira, Marta Sofia Morgado; Lopes, Paula Alexandra Antunes Brás; Martins, Cátia Falcão; Assunção, José Miguel Pestana; Alfaia, Cristina Maria Riscado Pereira Mate; Pinto, Rui Manuel Amaro; Prates, José António Mestre. "Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned piglets". BMC Veterinary Research 17 1 (2021): http://dx.doi.org/10.1186/s12917-021-02869-y.
    Published • 10.1186/s12917-021-02869-y
  17. Murru, Elisabetta; Lopes, Paula A.; Carta, Gianfranca; Manca, Claudia; Abolghasemi, Armita; Guil-Guerrero, Jose´ L.; Prates, José A. M.; Banni, Sebastiano. "Different Dietary N-3 Polyunsaturated Fatty Acid Formulations Distinctively Modify Tissue Fatty Acid and N-Acylethanolamine Profiles". Nutrients 13 2 (2021): 625. http://dx.doi.org/10.3390/nu13020625.
    Published • 10.3390/nu13020625
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    Published • 10.1016/j.psj.2020.11.034
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  20. "Influence of dietary supplementation with an amino acid mixture on inflammatory markers, immune status and serum proteome in LPS-challenged weaned piglets.". Animals 11 (2021): 1143.
    Open access • Published
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    Open access • Published
  22. Martins, Cátia Falcão; Pestana Assunção, José; Ribeiro Santos, David M.; Madeira, Marta Sofia Morgado dos S.; Alfaia, Cristina Maria Riscado Pereira Mate; Lopes, Paula Alexandra Antunes Brás; Coelho, Diogo Francisco Maurício; et al. "Effect of dietary inclusion of Spirulina on production performance, nutrient digestibility and meat quality traits in post-weaning piglets". Journal of Animal Physiology and Animal Nutrition (2020): http://dx.doi.org/10.1111/jpn.13470.
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    Published • 10.1016/j.psj.2019.11.069
  24. Coelho, Diogo; Lopes, Paula A.; Cardoso, Vânia; Ponte, Patrícia; Brás, Joana; Madeira, Marta S.; Alfaia, Cristina M.; et al. "A two-enzyme constituted mixture to improve the degradation of Arthrospira platensis microalga cell wall for monogastric diets". Journal of Animal Physiology and Animal Nutrition 104 (2020): 310-321. http://dx.doi.org/10.1111/jpn.13239.
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  25. Lopes, Paula Alexandra. "Impact of dietary incorporation of Spirulina (Arthrospira platensis) and exogenous enzymes on broiler performance, carcass traits, and meat quality". Poultry Science 99 (2020): 2519-2532.
    Published
  26. Coelho, Diogo; Lopes, Paula A.; Cardoso, Vânia; Ponte, Patrícia; Brás, Joana; Madeira, Marta S.; Alfaia, Cristina M.; et al. "Novel combination of feed enzymes to improve the degradation of Chlorella vulgaris recalcitrant cell wall". Scientific Reports 9 1 (2019): http://dx.doi.org/10.1038/s41598-019-41775-0.
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    10.1016/j.plefa.2018.07.010
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    10.1186/s12986-017-0218-y
  31. Lopes, Paula A.; Bandarra, Narcisa M.; Martins, Susana V.; Madeira, Marta S.; Ferreira, Júlia; Guil-Guerrero, José L.; Prates, José A. M.. "Docosahexaenoic acid (DHA) at the sn-2 position of triacylglycerols increases DHA incorporation in brown, but not in white adipose tissue, of hamsters". International Journal of Food Sciences and Nutrition 69 4 (2017): 458-471. http://dx.doi.org/10.1080/09637486.2017.1372390.
    10.1080/09637486.2017.1372390
  32. Madeira, Marta S; Rolo, Eva A; Lopes, Paula A; Ramos, Denis A; Alfaia, Cristina M; Pires, Virgínia MR; Martins, Susana V; Pinto, Rui MA; Prates, José AM. "Betaine and arginine supplementation of low protein diets improves plasma lipids but does not affect hepatic fatty acid composition and related gene expression profiling in pigs". Journal of the Science of Food and Agriculture 98 2 (2017): 598-608. http://dx.doi.org/10.1002/jsfa.8504.
    10.1002/jsfa.8504
  33. Madeira, Marta Sofia Morgado dos Santos; Rolo, Eva Sofia Alves; Pires, Virgínia Maria Rico; Alfaia, Cristina Maria Riscado Pereira Mate; Coelho, Diogo Francisco Maurício; Lopes, Paula Alexandra Antunes Brás; Martins, Susana Isabel Vargas; Pinto, Rui Manuel Amaro; Prates, José António Mestre. "Arginine supplementation modulates pig plasma lipids, but not hepatic fatty acids, depending on dietary protein level with or without leucine". BMC Veterinary Research 13 1 (2017): 145-159. http://dx.doi.org/10.1186/s12917-017-1063-y.
    10.1186/s12917-017-1063-y
  34. Madeira, M. S.; Lopes, P. A.; Costa, P.; Coelho, D.; Alfaia, C. M.; Prates, J. A. M.; Madeira, M.S.; et al. "Reduced protein diets increase intramuscular fat of psoas major, a red muscle, in lean and fatty pig genotypes". animal 11 11 (2017): 2094-2102. http://dx.doi.org/10.1017/s1751731117000921.
    10.1017/s1751731117000921
  35. Correia, C. S.; Alfaia, C. M.; Madeira, M. S.; Lopes, P. A.; Matos, T. J. S.; Cunha, L. F.; Prates, J. A. M.; Freire, J. P. B.. "Dietary inclusion of tomato pomace improves meat oxidative stability of young pigs". Journal of Animal Physiology and Animal Nutrition 101 6 (2017): 1215-1226. http://dx.doi.org/10.1111/jpn.12642.
    10.1111/jpn.12642
  36. Lopes, P. A.; Martins, A. P.; Martins, S. V.; Madeira, M. S.; Santos, N. C.; Moura, T. F.; Prates, J. A. M.; et al. "Higher membrane fluidity mediates the increased subcutaneous fatty acid content in pigs fed reduced protein diets". animal 11 4 (2016): 713-719. http://dx.doi.org/10.1017/s1751731116001968.
    10.1017/s1751731116001968
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    10.1017/s1751731116001373
  38. Bandarra, Narcisa M.; Lopes, Paula A.; Martins, Susana V.; Ferreira, Júlia; Alfaia, Cristina M.; Rolo, Eva A.; Correia, Jorge J.; et al. "Docosahexaenoic acid at the sn-2 position of structured triacylglycerols improved n-3 polyunsaturated fatty acid assimilation in tissues of hamsters". Nutrition Research 36 5 (2016): 452-463. http://dx.doi.org/10.1016/j.nutres.2015.12.015.
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    10.1002/ejlt.201600042
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    10.1016/j.plefa.2015.04.004
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    10.1016/j.bbrc.2015.01.116
  45. Rodrigues, Pedro O.; Martins, Susana V.; Lopes, Paula A.; Ramos, Cristina; Miguéis, Samuel; Alfaia, Cristina M.; Pinto, Rui M. A.; et al. "Influence of feeding graded levels of canned sardines on the inflammatory markers and tissue fatty acid composition of Wistar rats". British Journal of Nutrition 112 3 (2014): 309-319. http://dx.doi.org/10.1017/s0007114514000853.
    10.1017/s0007114514000853
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  47. Madeira, M. S.; Costa, P.; Alfaia, C. M.; Lopes, P. A.; Bessa, R. J. B.; Lemos, J. P. C.; Prates, J. A. M.. "The increased intramuscular fat promoted by dietary lysine restriction in lean but not in fatty pig genotypes improves pork sensory attributes1". Journal of Animal Science 91 7 (2013): 3177-3187. http://dx.doi.org/10.2527/jas.2012-5424.
    10.2527/jas.2012-5424
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  49. Martins, A.P.; Lopes, P.A.; Madeira, M.S.; Martins, S.V.; Santos, N.C.; Moura, T.F.; Prates, J.A.M.; Soveral, G.. "Differences in lipid deposition and adipose membrane biophysical properties from lean and obese pigs under dietary protein restriction". Biochemical and Biophysical Research Communications 423 1 (2012): 170-175. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862693223&partnerID=MN8TOARS.
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    10.1016/j.jfca.2010.11.008
  54. Lopes, Paula A.; Martins, Susana V.; Viana, Ricardo S.J.; Ramalho, Rita M.; Alfaia, Cristina M.; Pinho, Mário S.; Jerónimo, Eliana; et al. "Contrasting apoptotic responses of conjugated linoleic acid in the liver of obese Zucker rats fed palm oil or ovine fat". Prostaglandins, Leukotrienes and Essential Fatty Acids 85 2 (2011): 89-96. http://dx.doi.org/10.1016/j.plefa.2011.04.026.
    10.1016/j.plefa.2011.04.026
  55. Martins, A. P.; Lopes, P. A.; Costa, A. S. H.; Martins, S. V.; Santos, N. C.; Prates, J. A. M.; Moura, T. F.; et al. "Differential mesenteric fat deposition in bovines fed on silage or concentrate is independent of glycerol membrane permeability". animal 5 12 (2011): 1949-1956. http://dx.doi.org/10.1017/s1751731111001091.
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  65. Lopes, Paula Alexandra; Gaspar, Gisela; Napoleão, Patrícia; Santos, Maria Cristina; Pavão, Maria Leonor; Viegas-Crespo, Ana Maria. "Comparison of apolipoprotein E polymorphism and other atherosclerotic risk factors in two portuguese populations: the influence of insularity". Brazilian Archives of Biology and Technology 50 5 (2007): 803-813. http://dx.doi.org/10.1590/s1516-89132007000500008.
    10.1590/s1516-89132007000500008
  66. Lopes, P.A.; Gaspar, G.; Napoleão, P.; Santos, M.C.; Pavão, M.L.; Viegas-Crespo, A.M.. "Comparison of apolipoprotein E polymorphism and other atherosclerotic risk factors in two Portuguese populations - The influence of insularity". Brazilian Archives of Biology and Technology 50 5 (2007): 803-813. http://www.scopus.com/inward/record.url?eid=2-s2.0-37749049774&partnerID=MN8TOARS.
  67. Martins, S.V.; Lopes, P.A.; Alfaia, C.M.; Ribeiro, V.S.; Guerreiro, T.V.; Fontes, C.M.G.A.; Castro, M.F.; Soveral, G.; Prates, J.A.M.. "Contents of conjugated linoleic acid isomers in ruminant-derived foods and estimation of their contribution to daily intake in Portugal". British Journal of Nutrition 98 6 (2007): 1206-1213. http://www.scopus.com/inward/record.url?eid=2-s2.0-36649008513&partnerID=MN8TOARS.
    10.1017/S0007114507781448
  68. Napoleão, P.; Lopes, P.A.; Santos, M.; Steghens, J.-P.; Viegas-Crespo, A.M.; Pinheiro, T.. "Redox balance and blood elemental levels in atherosclerosis". Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 249 1-2 (2006): 702-705. http://dx.doi.org/10.1016/j.nimb.2006.03.121.
    10.1016/j.nimb.2006.03.121
  69. Pavão, M. L.; Figueiredo, T.; Santos, V.; Lopes, P. A.; Ferin, R.; Santos, M. C.; Nève, J.; Viegas-Crespo, A. M.. "Whole blood glutathione peroxidase and erythrocyte superoxide dismutase activities, serum trace elements (Se, Cu, Zn) and cardiovascular risk factors in subjects from the city of Ponta Delgada, Island of San Miguel, The Azores Archipelago, Portugal". Biomarkers 11 5 (2006): 460-471. http://dx.doi.org/10.1080/13547500600625828.
    10.1080/13547500600625828
  70. Marques, C.C.; Nunes, A.C.; Pinheiro, T.; Lopes, P.A.; Santos, M.C.; Viegas-Crespo, A.M.; Ramalhinho, M.G.; Mathias, M.L.. "An assessment of time-dependent effects of lead exposure in Algerian mice (Mus spretus) using different methodological approaches". Biological Trace Element Research 109 1 (2006): 75-89. http://www.scopus.com/inward/record.url?eid=2-s2.0-29944447135&partnerID=MN8TOARS.
  71. Lopes, P.A.; Napoleão, P.; Pinheiro, T.; Ceia, F.; Steghens, J.-P.; Pavão, M.L.; Santos, M.C.; Viegas-Crespo, A.M.. "Systemic markers of the redox balance and apolipoprotein E polymorphism in atherosclerosis: The relevance for an integrated study". Biological Trace Element Research 112 1 (2006): 57-75. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748352972&partnerID=MN8TOARS.
    10.1385/BTER:112:1:57
  72. Bettencourt, C.; Montiel, R.; Santos, C.; Pavão, M.L.; Viegas-Crespo, A.M.; Lopes, P.A.; Lima, M.. "Polymorphism of the APOE locus in the Azores Islands (Portugal)". Human Biology 78 4 (2006): 509-512. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846253576&partnerID=MN8TOARS.
  73. Lopes, Paula A.; Santos, Maria C.; Vicente, Lui´s; Viegas-Crespo, Ana M.. "Effect of cigarette smoking on serum a-tocopherol and the lipid profile in a Portuguese population". Clinica Chimica Acta 348 1-2 (2004): 49-55. http://dx.doi.org/10.1016/j.cccn.2004.04.033.
    10.1016/j.cccn.2004.04.033
  74. Lopes, P.A.; Santos, M.C.; Vicente, L.; Rodrigues, M.O.; Pavão, M.L.; Nève, J.; Viegas-Crespo, A.M.. "Trace element status (Se, Cu, Zn) in healthy Portuguese subjects of Lisbon population: A reference study". Biological Trace Element Research 101 1 (2004): 1-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-9144239905&partnerID=MN8TOARS.
  75. Viegas-Crespo, A.M.; Lopes, P.A.; Pinheiro, M.T.; Santos, M.C.; Rodrigues, P.D.; Nunes, A.C.; Marques, C.; Mathias, M.L.. "Hepatic elemental contents and antioxidant enzyme activities in Algerian mice (Mus spretus) inhabiting a mine area in central Portugal". Science of The Total Environment 311 1-3 (2003): 101-109. http://dx.doi.org/10.1016/s0048-9697(03)00136-0.
    10.1016/s0048-9697(03)00136-0
  76. Viegas-Crespo, A.M.; Lopes, P.A.; Pinheiro, M.T.; Santos, M.C.; Rodrigues, P.D.; Nunes, A.C.; Marques, C.; Mathias, M.L.. "Hepatic elemental contents and antioxidant enzyme activities in Algerian mice (Mus spretus) inhabiting a mine area in central Portugal". Science of the Total Environment 311 1-3 (2003): 101-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037788051&partnerID=MN8TOARS.
    10.1016/S0048-9697(03)00136-0
  77. Lopes, Paula Alexandra; Lopes, P.A.; Viegas-Crespo, A.M.; Nunes, A.C.; Pinheiro, T.; Marques, C.; Santos, M.C.; Mathias, M.D.L.. "Influence of age, sex and sexual activity on trace element levels and antioxidant enzyme activities in field mice (Apodemus sylvaticus and Mus spretus). Biological Trace Element Research 85: 227-239.". Biological Trace Element Research 85 3 (2002): 227-239. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036200172&partnerID=MN8TOARS.
    10.1385/BTER:85:3:227
  78. LOPES, P; PINHEIRO, T; SANTOS, M; DALUZMATHIAS, M; COLLARESPEREIRA, M; VIEGASCRESPO, A. "Response of antioxidant enzymes in freshwater fish populations (Leuciscus alburnoides complex) to inorganic pollutants exposure". The Science of The Total Environment 280 1-3 (2001): 153-163. http://dx.doi.org/10.1016/s0048-9697(01)00822-1.
    10.1016/s0048-9697(01)00822-1
  79. Lopes, Paula Alexandra. "Teresa Pinheiro, Patrícia Rocha, Paula A. Lopes, Ana Maria Viegas-Crespo, Maria Cristina Santos, Maria da Luz Mathias (2001). Laboratory testing of biochemical effects of Mn, Fe and Se in the Algerian mouse (Mus spretus). The Ecotoxicology and Environmental Restoration 4: 60-63.". The Ecotoxicology and Environmental Restoration 4 (2001): 60-63.
  80. Lopes, P.A.; Pinheiro, T.; Santos, M.C.; Da Luz Mathias, M.; Collares-Pereira, M.J.; Viegas-Crespo, A.M.. "Response of antioxidant enzymes in freshwater fish populations (Leuciscus alburnoides complex) to inorganic pollutants exposure". Science of the Total Environment 280 1-3 (2001): 153-163. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035802915&partnerID=MN8TOARS.
    10.1016/S0048-9697(01)00822-1
Thesis / Dissertation
  1. Lopes, Paula Alexandra. "Redox balance and risk factors associated with atherogenesis in humans". PhD, Universidade de Lisboa Faculdade de Ciências, 2006.
  2. Lopes, Paula Alexandra. "Pesquisa de parâmetros bioquímicos indicadores de metais pesados em espécies piscícolas (peixes dulciaquícolas) e ripícolas (micromamíferos) do Guadiana". Degree, Universidade de Lisboa Faculdade de Ciências, 1997.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/09/20 On the use of transgenic mice for Alzheimer’s disease Global Summit and Expo on Animal Science and Veterinary Medicine
Apex Global Meetings (Praga, Czech Republic)
2024/02/08 Mackerel and quinoa daily intake mitigates cognitive decline in Alzheimer’s disease mice 54th Meeting of the Portuguese Society of Pharmacology, 42nd Meeting of Clinical Pharmacology and 23rd Meeting of Toxicology
Sociedade Portuguesa de Farmacologia (Lisboa, Portugal)
2023/11/08 Estudo piloto sobre lípidos estruturados e por medida: novas estratégias sustentáveis em ácido docosahexaenóico (DHA) para a prevenção da doença de Alzheimer Seminários do Mestrado em Biologia Humana e Ambiente (BHA)
Faculdade de Ciências da Universidade de Lisboa, Departamento de Biologia Animal (Lisboa, Portugal)
2023/09/19 Different dietary n-3 polyunsaturated fatty acid formulations modify tissue fatty acid and N-acylethanolamine profiles 19th Euro Fed Lipid Congress and Expo “Fats, Oils and Lipids: from Raw Materials to Consumer Expectations”
Euro Fed Lipid (Poznan, Poland)
2023/07/14 Testimony on a successful lab protocol to disrupt Chlorella vulgaris microalga cell wall Spotlight interview for protocols.io
protocols.io (on line via zoom)
2022/11/11 Tissue specific variation of aquaporins and cytokines transcriptional profile in piglets under LPS challenge CIISA Congress 2022 – “Innovation in animal, veterinary and biomedical sciences"
CIISA (Lisboa, Portugal)
2021/10/20 Effects of dietary CLA on n-3 HUFA score and N-acylethanolamides biosynthesis in the liver of obese Zucker rats 18th Euro Fed Lipid Congress “Fats, oils and lipids for a healthy and sustainable world”
Euro Fed Lipid (on line)
2021/10/16 Downregulation of aquaporins gene expression by glutamine or cystine-enriched diets in the small intestine of piglets XXI National Congress of Biochemistry “Tunning biochemistry with life and society”
Sociedade Portuguesa de Bioquímica (Évora, Portugal)
2019 Different patterns of aquaporin gene expression in white and brown adipose tissue from hamsters in response to feeding n-3 LCPUFA in lipid structural formats, triacylglycerols versus ethyl esters 17th Euro Fed Lipid Congress and Expo
(Sevilha, Spain)
2019 Influence of Spirulina as feed ingredient and exogenous recombinant enzymes on broiler chickens performance AlgaEurope 2019
(Paris, France)
2018 Markers of neuroprotection of combined EPA and DHA provided by fish oil are higher than those of EPA (Nannochloropsis) and DHA (Schizochytrium) from microalgae oils in Wistar rats 16th Euro Fed Lipid Congress and Expo
(Belfast, Ireland)
2018 Feeding strategies to improve fat partitioning and meat quality in pigs: from genetic background to dietary protein and amino acids CIISA Congress - Exploring the boundaries of animal, veterinary and biomedical sciences
(Lisboa, Portugal)
2012 Increased fluidity in adipose membranes from genetically obese pigs is independent of carbon chain length and unsaturation degree of fatty acids 10th Euro Fed Lipid Congress
(Cracóvia, Poland)
2012 Assessing fat deposition between subcutaneous fat tissue and muscle in lean and obese pigs fed on reduced protein diets 10th Euro Fed Lipid Congress
(Cracóvia, Poland)
2011 Omega 3 Index in RBC and Protective Cardiometabolic Profile International Workshop: Obesity and Diabetes-associated co-morbidities - Metabolic Syndrome
(Lisboa, Portugal)
2011 Differential cellularity and fatty acid profile in subcutaneous and mesenteric fat depots from Portuguese bovine breeds 57th International Congress of Meat Science and Technology
(Ghent, Belgium)
2011 Modulation of conjugated linoleic acid effects by saturated fat diets 9th Euro Fed Lipid Congress
(Roterdão, Netherlands)
2011 Contrasting mesenteric fat deposition in bovines fed on silage or concentrate is independent of membrane permeability to glycerol 9th Euro Fed Lipid Congress
(Munique, Germany)
2010 Conjugated linoleic acid impairs adipose plasma membrane permeability and fluidity IV Spanish Portuguese Biophysical Congress
(Zaragoza, Spain)
2010 Effect of dietary conjugated linoleic acid isomers on water and glycerol permeability of kidney membranes 8th Euro Fed Lipid Congress
(Munique, Germany)
2010 Using DNA microarrays to elucidate the mechanisms of meat quality 8th Euro Fed Lipid Congress
(Munique, Germany)
2010 Fatty acid composition and conjugated isomers of linoleic acid (CLA) of some edible animal by-products 8th Euro Fed Lipid Congress
(Munique, Germany)
2009 Differential effects of CLA on serum lipid and cytokine profiles of obese Zucker rats fed saturated fats from vegetal and animal origin 7th Euro Fed Lipid Congress
(Graz, Austria)
2009 Molecular pathways of CLA-Induced apoptosis under different fat based diets in obese Zucker rats 7th Euro Fed Lipid Congress
(Graz, Austria)
2009 Effect of graded levels of dietary n-3/n-6 PUFA on blood and brain lipids 7th Euro Fed Lipid Congress
(Graz, Austria)
2008 Resposta apoptótica no modelo Zucker: efeitos da suplementação de CLA e da dieta-base com gorduras animal e vegetal Seminários de Divulgação Científica do CIISA
CIISA (Lisboa, Portugal)
2007 Estimation of the daily intake of CLA isomers in the Portuguese population II International Congress on Conjugated Linoleic Acid (CLA): from Experimental Models to Human Application
(Sardenha, Italy)
2007 How does cis9,trans11 and trans10,cis12-CLA isomers added to a saturated fat diet affect the size and number of adipocytes in Wistar rats? II International Congress on Conjugated Linoleic Acid (CLA): from Experimental Models to Human Application
(Sardenha, Italy)
2007 Effects of CLA isomers on apoptotic pathways and membrane permeability in obese and hyperlipidemic rats – the Zucker model Jornadas do Ensino Pós-Graduado da FMV – Simpósio do CIISA
CIISA (Lisboa, Portugal)
2007 Influence of conjugated octadecadienoic acids on lipid metabolism and inflammatory mediators in normolipidemic rats Jornadas do Ensino Pós-Graduado da FMV – Simpósio do CIISA
CIISA (Lisboa, Portugal)
2002 Serum vit. E levels and its relationship with the lipid profile and tobacco consumption in inhabitants of Lisbon 3rd International Meeting. Advances in Trace Elements, Minerals & Vitamins in Humans: Functional and Clinical Aspects
(Monastir, Tunisia)
2002 Ecotoxicological study of a population of the Algerian mouse inhabiting a mine area at Portugal 8th International Conference Rodens & Spatium
(Louvain-la-Neuve , Belgium)
2001 Serum copper levels and its relationship with hormone therapy and pregnancy in portuguese women 1st International FESTEM Congress on Trace Elements and Minerals in Medicine and Biology
(Veneza, Italy)
2001 Blood antioxidant enzymes and lipid peroxidation index in a sample of the human population of Lisbon 1st International FESTEM Congress on Trace Elements and Minerals in Medicine and Biology
(Veneza, Italy)
2000 Estudo da acumulação de elementos minerais nas brânquias e no fígado de ciprinídeos expostos a uma intoxicação aguda de cobre. 3º Congresso Ibérico de Contaminação e Toxicologia Ambiental – CICTA 2000 – Por um Desenvolvimento Ambiental Sustentado no Próximo Milénio
CICTA 2000 (Faro, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2023/09/18 - 2024/09/17 Tailor-made structured lipids: a pilot study on sustainable sources of docosahexaenoic fatty acid (DHA) for the prevention of Alzheimer’s disease
Supervisor
Universidade de Lisboa - Faculdade de Medicina Veterinária, Portugal
2020/06/01 - 2023/05/31 Valorização de dietas com microalgas para a alimentação de suínos em acabamento e para a melhoria da qualidade da sua carne
Co-supervisor
Bolsa de Pós-Doutoramento, ref.: FCT/SFRH/BPD/116816/2016, 2º triénio (Other)
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2019/10/01 - 2020/09/30 Effect of dietary amino acids on glycerol absorption via intestinal aquaporins: a mechanism for fat accumulation?
Co-supervisor
Mestrado em Ciências Biofarmacêuticas (Master)
Universidade de Lisboa - Faculdade de Farmácia, Portugal
2017/06/01 - 2020/05/31 Valorização de dietas com microalgas para a alimentação de suínos em acabamento e para a melhoria da qualidade da sua carne
Co-supervisor
Bolsa de Pós-Doutoramento, ref.: FCT/SFRH/BPD/116816/2016, 1º triénio (Other)
Universidade de Lisboa - Faculdade de Medicina Veterinária, Portugal
2017 - 2018 Modulation of aquaporins gene expression by n-3 PUFA lipid structures in white and brown adipose tissue from hamsters
Co-supervisor
Mestrado em Ciências Biofarmacêuticas (Master)
Universidade de Lisboa - Faculdade de Farmácia, Portugal
2013 - 2015 Metabolic fate and health properties of structured triacylglycerols rich in n-3 long chain polyunsaturated fatty acids
Co-supervisor
Bolsa de Pós-Doutoramento, FCT/SFRH/BPD/63019/2009, 2º triénio (Other)
Universidade de Lisboa - Faculdade de Medicina Veterinária, Portugal
2010 - 2012 Searching for new insights into the regulation of lipid metabolism through the use of novel conjugated linoleic acid (CLA) isomers in distinct mammalian adipose systems
Co-supervisor
Bolsa de Pós-Doutoramento, FCT/SFRH/BPD/63019/2009, 1º triénio (Other)
Universidade de Lisboa - Faculdade de Medicina Veterinária, Portugal
2009 - 2010 Effect of breed and diet on morphometric pattern of subcutaneous and mesenteric fat from native bovines
Co-supervisor
Mestrado em Engenharia Zootécnica/Produção Animal (Master)
Universidade de Lisboa - Faculdade de Medicina Veterinária, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2023/07/24 A qualidade da carne bovina: o valor da certificação
(Thesis) Main arguer
João Miguel Canelas Carreiro (Master)
Universidade de Lisboa - Faculdade de Medicina Veterinária, Portugal
2022/12/23 Aquaporins as biomarkers for pancreatic cancer
(Thesis) Main arguer
Elisabete Sofia Antunes Dias Nobre Fonseca (Master)
Universidade Nova de Lisboa, Portugal
2022/10/27 Contamination in the city: synantropic species as bioindicators of urban environmental exposure
(Thesis) Main arguer
Elizandra Matos Cardoso (PhD)
Universidade de Lisboa Faculdade de Ciências, Portugal
2021/12/28 Involvement of aquaporin-3 in melanoma
(Thesis) Main arguer
Andreia Gonçalves Silva (Master)
Universidade de Lisboa - Faculdade de Farmácia, Portugal
2021/02/26 Aquaporins involvement in hepatic ischemia reperfusion injury
(Thesis) Main arguer
Jessica Alexandra Silva Fernandes (Master)
Universidade de Lisboa - Faculdade de Farmácia, Portugal
2018/11/22 Modulation of aquaporin 7 in adipocytes by miRNAs
(Thesis) Main arguer
André Filipe Paulo Gomes (Master)
Universidade de Lisboa - Faculdade de Farmácia, Portugal
2017/02/20 Aquaporins in metabolic syndrome: new targets for drug discovery
(Thesis) Main arguer
Inês Margarida Vieira da Silva (Other)
Universidade de Lisboa - Faculdade de Farmácia, Portugal
2010 New insights into biological effects of conjugated linoleic acid and saturated fats in body fat composition, obesity and related disorders: experimental studies in the normal-weight and obese Zucker rats
(Thesis) Arguer
Susana Isabel Vargas Martins (PhD)
Universidade de Lisboa - Faculdade de Medicina Veterinária, Portugal

Committee member

Activity description
Role
Institution / Organization
2015 - Current Membro da Comissão Científica do CIISA - Centro de Investigação Interdisciplinar em Sanidade Animal
Member

Interview (tv / radio show)

Program Topic
2001 - 2001 Entrevista Promoção e Divulgação da Faculdade de Ciências da Universidade de Lisboa

Other jury / evaluation

Activity description Institution / Organization
2011 - Current Peer review process of scientific manuscripts for the following journals: The Journal of Nutrition, PLoS One, Journal of Animal Science, Molecular Nutrition and Food Research, Lipids, Meat Science, Nutrition, Nutrition Research, Journal of Agricultural and Food Chemistry, Biological Trace Element Research, Food and Chemical Toxicology, International Journal of Food Sciences and Nutrition, Frontiers in Genetics and Scientific Reports.
2023/07/01 - 2023/09/10 As president of the jury for the selection of a Master degree research grant for the scientific project "Tailor-made structured lipids: a pilot study on sustainable sources of docosahexaenoic fatty acid (DHA) for the prevention of Alzheimer’s disease" (ref.: FCT.2022.08133.PTDC) at the Faculty of Veterinary Medicine, University of Lisbon, july 2023. Universidade de Lisboa, Portugal
2015/10 - 2015/10 Evaluation of the scientific research project, entitled: "The influence of biological factors on pro/antioxidant balance in persons aged 20-40 years", ref. Stock Exchange 2014/13/N/NZ7/00289, National Center for Science from Poland. Universidade de Lisboa - Faculdade de Farmácia, Portugal
2013/11 - 2013/11 - As substitute member of the jury for selection of a research grant within the research project "Investigation of anti-angiogenic therapy effect with Dll4Fc in the formation of tumor metastases" (ref .: PTDC / SAU-ONC / 121742/2010) at the Faculty of Veterinary Medicine, Technical University of Lisbon in november 2013. Universidade de Lisboa - Faculdade de Farmácia, Portugal
2010/05 - 2010/05 As member of the jury for the selection of a research grant within the research project "Improving fat partioning and nutritional quality in pigs: developing feeding strategies and providing insights into genetic and metabolic mechanisms" (ref .: FCT/PTDC/CVT/099210/2008) at the Faculty of Veterinary Medicine, Technical University of Lisbon in may 2010. Universidade de Lisboa - Faculdade de Farmácia, Portugal
2009/03 - 2009/03 As member of Rosicka Grace Walton jury for a research grant (Sigma Delta Epsilon/Graduate Women in Science Pre-Doctoral Fellowship - Evaluation Form for Graduate Women in Science Fellowships - Call 2008-2009). Universidade de Lisboa - Faculdade de Farmácia, Portugal
Distinctions

Award

2020 Best Paper Award for a PhD paper
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
2010 Best Poster Award
8th Euro Fed Lipid Congress, Munich-Germany, Germany
2005 Best Poster Award
TEMA 12 - University of Ulster, Dublin-Ireland, Ireland
2003 Best Poster Award
4th International Symposium on Trace Elements in Human: New Perspectives, Athens-Greece, Greece