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Joana Carrapiço Gonçalves completed her Integrated Master's Degree in Pharmaceutical Sciences in 2014 and her PhD in Pharmaceutical Sciences, specializing in Pharmacology and Pharmacotherapy, at the Faculty of Pharmacy of the University of Coimbra in 2022. Her research focused on the intranasal administration of centrally acting drugs, the identification of BCRP modelers through in vitro studies, and the development and validation of HPLC analytical quantification techniques. In the period between submitting her thesis and taking her doctoral exams, she worked as a hospital pharmacist, with a view to acquiring skills and experience in clinical practice, in addition to the three years she spent working in community pharmacy. She currently works as an assistant professor at Lusófona University, teaching Pharmacotherapy, Pharmacokinetics, Non-Prescription Pharmacotherapy, Pharmaceutical Communication and Practice, Functional Anatomy, Cell Biology, Biochemistry and Physiology. He maintains the legacy of scientific research and is starting to join the CBIOS group. The acquisition of new knowledge, with medicine and pathology as its purpose, is his main purpose.
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Identification

Personal identification

Full name
JOANA CARRAPIÇO GONÇALVES

Citation names

  • Gonçalves, Joana

Author identifiers

Ciência ID
0416-A28A-C92D
ORCID iD
0000-0002-1872-4387

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
English Elementary (A2) Upper intermediate (B2) Intermediate (B1) Intermediate (B1)
Spanish; Castilian Intermediate (B1) Elementary (A2) Beginner (A1) Intermediate (B1)
Education
Degree Classification
2023/06/22 - 2023/06/26
Concluded
 Manipulação e Análise da Expressão Génica (Outros)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2023/05/25 - 2023/06/03
Concluded
 Fundamentos de Cultura Celular (Outros)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2016/09/16 - 2022/02/23
Concluded
 Doutoramento Ciências Farmacêuticas (Doutoramento)
Major in Farmacologia e Farmacoterapia
Universidade de Coimbra Faculdade de Farmácia, Portugal
"Nose-to-brain delivery of lacosamide, levetiracetam and zonisamide and the impacto f BCRP efflux: an in vitro/in vivo approach”" (THESIS/DISSERTATION)
 Aprovada com Louvor e Distinção
2019/06 - 2019/06
Concluded
 Curso Prático de Ciências em Animais de Laboratório (Outros)
Sociedade Portuguesa de Ciências em Animais de Laboratório , Portugal
 Aprovada
2018/03/01 - 2018/09/13
Concluded
 Curso Teórico de Ciências de Animais de Laboratório (Outros)
Sociedade Portuguesa de Ciências em Animais de Laboratório , Portugal
 Aprovada
2017 - 2017
Concluded
 Cell Culture and Tissue Training Course. (Outros)
CNC.IBILI, Portugal
 Aprovada
2008/09 - 2014/02
Concluded
 Mestrado Integrado Ciências Farmacêuticas (Mestrado integrado)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
"Nanotecnologia Aplicada à Pele" (THESIS/DISSERTATION)
2013 - 2013
Concluded
 Administração de Injetáveis (Outros)
Cofanor, Portugal
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2024/09/01 - Current Invited Assistant Professor (University Teacher) Universidade Nova de Lisboa Medical School, Portugal
Universidade Nova de Lisboa Medical School, Portugal
2023/09/01 - 2024/08/31 Assistant Professor (University Teacher) Universidade Lusófona de Humanidades e Tecnologias, Portugal
Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2022/08/30 - 2023/08/29 Invited Assistant Professor (University Teacher) Universidade Lusófona de Humanidades e Tecnologias, Portugal
Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2018/09 - 2018/12 Trainee Assistant (University Teacher) Universidade de Coimbra Faculdade de Farmácia, Portugal
Universidade de Coimbra Faculdade de Farmácia, Portugal

Other Careers

Category
Host institution 		Employer
2015/11/15 - 2016/11/15 Técnico Farmacêutico 1 Cl (Técnico Farmacêutico) Farmácia Mata Mourisca, Portugal
2015/04/01 - 2015/10/30 Técnico Farmacêutico 1 Cl (Técnico Farmacêutico) Farmácia Nova, Portugal
Farmácia Nova, Portugal
2014/05/01 - 2015/03 Técnico Farmacêutico Estagiário (Técnico Farmacêutico) Farmácia Freixedas, Portugal

Others

Category
Host institution 		Employer
2020/06/23 - 2022/04/08 Técnico Superior de Farmácia Hospital do Espírito Santo EPE, Portugal
2016/09/16 - 2022/02/23 Estudante doutoramento Universidade de Coimbra Faculdade de Farmácia, Portugal
Universidade de Coimbra Faculdade de Farmácia, Portugal
Projects

Contract

Designation Funders
2019/02/26 - Current N2BD - Desenvolvimento de uma nanoplataforma multifuncional Nose-to-Brain para o tratamento da Depressão e prevenção do desenvolvimento de fármaco-resistências
CENTRO-01-0145-FEDER-030752
Researcher
Universidade de Coimbra Faculdade de Farmácia, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
Ongoing
Outputs

Publications

Conference poster
  1. Goncalves, Joana; Silva, Soraia; Alves, Gilberto; Fortuna, Ana. "How does the device determine nose-to-brain drug delivery to mice?". Paper presented in Conference Drug Delivery to the Lungs, 2019.
  2. Gonçalves, Joana; Silva, Rui; Almeida, Anabela; Bicker, Joana; Sales, Francisco; Falcao, Amilcar. "Therapeutic drug monitoring of levetiracetam: Pharmacokinetic characterization and compliance assessment of epileptic patients". Paper presented in Annual Scientific Meeting of the European Society for Clinical Investigation, 2019.
  3. Joana Gonçalves; Joana Bicker; Soraia Silva; Gilberto Alves; Amilcar Falcao; Ana Fortuna. "Nose-to-brain delivery of levetiracetam: preclinical evidence". Paper presented in Annual Scientific Meeting of the European Society for Clinical Investigation, 2019.
    10.1158/1538-7445.am2018-4641
  4. Silva, Luís; Almeida, Anabela; Silva, Rui; Gonçalves, Joana; Sales, Francisco; Silva, Ana; Falcão, Amílcar; Fortuna, Ana. "Caracterização do perfil farmacocinético do levetiracetam em doentes Portugueses com epilepsia". Paper presented in 31º Encontro Nacional de Epileptologia, 2019.
  5. Silva, Rui; Paulino, Jamal; Almeida, Anabela; Gonçalves, Joana; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana. "Levetiracetam therapy individualization: predictive performance of three pharmacokinetic models.". Paper presented in 47th ESCP symposium on clinical pharmacy Personalised pharmacy care, 2018.
  6. Gonçalves, Joana; Paulino, Jamal; Gouveia, Filipa; Silva, Ana; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana. "Monitoring lacosamide, levetiracetam, zonisamide in plasma of epileptic patients: personalizing the pharmacotherapy of levetiracetam". Paper presented in 47th ESCP symposium on clinical pharmacy Personalised pharmacy care, 2018.
  7. Gonçalves, Joana; Paulino, Jamal; Sales, Francisco; Falcao, Amilcar; Fortuna, Ana. "Desenvolvimento e validação de um método para quantificação simultânea de lacosamida, levetiracetam e zonisamida no plasma de doentes epiléticos". Paper presented in Encontro Nacional de Epileptologia, 2018.
Journal article
  1. Gonçalves, Joana; Alves, Gilberto; Fonseca, Carla; Carona, Andreia; Bicker, Joana; Falcão, Amílcar; Fortuna, Ana. "Is intranasal administration an opportunity for direct brain delivery of lacosamide?". European Journal of Pharmaceutical Sciences 157 (2021): 105632. http://dx.doi.org/10.1016/j.ejps.2020.105632.
    Published • 10.1016/j.ejps.2020.105632
  2. Gonçalves, Joana; Silva, Soraia; Gouveia, Filipa; Bicker, Joana; Falcão, Amílcar; Alves, Gilberto; Fortuna, Ana. "A combo-strategy to improve brain delivery of antiepileptic drugs: Focus on BCRP and intranasal administration". International Journal of Pharmaceutics 593 (2021): 120161. http://dx.doi.org/10.1016/j.ijpharm.2020.120161.
    Published • 10.1016/j.ijpharm.2020.120161
  3. Gonçalves, Joana; Alves, Gilberto; Carona, Andreia; Bicker, Joana; Vitorino, Carla; Falcão, Amílcar; Fortuna, Ana. "Pre-Clinical Assessment of the Nose-to-Brain Delivery of Zonisamide After Intranasal Administration". Pharmaceutical Research 37 4 (2020): 74. http://dx.doi.org/10.1007/s11095-020-02786-z.
    Published • 10.1007/s11095-020-02786-z
  4. Gouveia, Filipa; Bicker, Joana; Gonçalves, Joana; Alves, Gilberto; Falcão, Amílcar; Fortuna, Ana. "Liquid chromatographic methods for the determination of direct oral anticoagulant drugs in biological samples: A critical review". Analytica Chimica Acta 1076 (2019): 18-31. http://dx.doi.org/10.1016/j.aca.2019.03.061.
    Published • 10.1016/j.aca.2019.03.061
  5. Gonçalves, Joana; Bicker, Joana; Gouveia, Filipa; Liberal, Joana; Oliveira, Rui Caetano; Alves, Gilberto; Falcão, Amílcar; Fortuna, Ana. "Nose-to-brain delivery of levetiracetam after intranasal administration to mice". International Journal of Pharmaceutics 564 (2019): 329-339. http://dx.doi.org/10.1016/j.ijpharm.2019.04.047.
    Published • 10.1016/j.ijpharm.2019.04.047
  6. Goncalves, Joana; Bicker, Joana; Alves, Gilberto; Fortuna, Ana; Falcao, Amilcar. "Relevance of Breast Cancer Resistance Protein to Brain Distribution and Central Acting Drugs: A Pharmacokinetic Perspective". Current Drug Metabolism 19 12 (2018): 1021-1041. http://dx.doi.org/10.2174/1389200219666180629121033.
    Published • 10.2174/1389200219666180629121033
  7. Gonçalves, Joana; Alves, Gilberto; Bicker, Joana; Falcão, Amílcar; Fortuna, Ana. "Development and full validation of an innovative HPLC-diode array detection technique to simultaneously quantify lacosamide, levetiracetam and zonisamide in human plasma". Bioanalysis 10 8 (2018): 541-557. http://dx.doi.org/10.4155/bio-2017-0199.
    Published • 10.4155/bio-2017-0199
  8. Fortuna, Ana. "Effect of Kidney Function on Amikacin Pharmacokinetics on Hospitalized Patients: Knowledge to Improve Therapy". Bioequivalence & Bioavailability International Journal 1 2 (2017): 000107. http://dx.doi.org/10.23880/beba-16000107.
    Published • 10.23880/beba-16000107

Other

Other output
  1. How does the device determine nose-to-brain drug delivery to mice? Journal of Aerosol Medicine and Pulmonary Drug Delivery. 33 2 (2019): A4-A5. 2019. Gonçalves, Joana.
  2. Monitoring lacosamide, levetiracetam, zonisamide in plasma of epileptic patients: personalizing the pharmacotherapy of levetiracetam. Abstract published in International Journal of Clinical Pharmacy. 41 (2018): 289-383.. 2018. Gonçalves, Joana; Paulino, Jamal; Gouveia, Filipa; Silva, Ana; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana. https://doi.org/10.1007/s11096-018-0759-9.
  3. Levetiracetam therapy individualization: predictive performance of three pharmacokinetic models. Abstract publish in International Journal of Clinical Pharmacy. 41 (2018): 289-383. 2018. Silva, Rui; Paulino, Jamal; Almeida, Anabela; Gonçalves, Joana; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana. https://doi.org/10.1007/s11096-018-0759-9.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2020/02/06 Hight Performace Chromatography Coupled to Diode Array to Support Pharmacokinetic Monitoring of Apixaban, Dabigatran, Edoxaban and Rivaroxaban Sociedade Portuguesa de Farmacologia
2020/02/06 Pharmacokinetics of Zonisamide after intranasal Administration to mice Sociedade Portuguesa de Farmacologia
2019/03/08 Avaliação da adesão terapêutica em doentes com epilepsia medicados com levetiracetam recorrendo à monitorização farmacocinética 31º Encontro Nacional de Epileptologia
Liga Portuguesa Contra a Epilepsia (Porto, Portugal)
2019/02/08 Intranasal administration of Levetiratecam in mice: is it a promising nose-to-brain strategy?
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2018/03/09 Levetiracetam therapy individualization: predictive performance of three pharmacokinetic models. 30º Encontro Nacional de Epileptologia
Liga Portuguesa Contra a Epilepsia (Coimbra, Portugal)
Distinctions

Award

2018 Atribuição de Melhor Apresentação em Forma de Poster intitulado “Desenvolvimento e validação de um método para quantificação simultânea de lacosamida, levetiracetam e zonisamida no plasma de doentes epiléticos”
30º Encontro Nacional de Epileptologia, Portugal