Pedro José Moreira Sobral (001B-EB58-C8B2)

Curriculum Vitae

Pedro José Moreira Sobral

I am a truly committed and determined person, highly dedicated and motivated. I strive daily to address the challenges in my work and achieve successfully my goals. This allowed me to have success in my academic path. During my academic path, I have developed a solid analytical thinking due to the high requirements of the curricular program. At the moment, I am a PhD student working on the development of novel molecules with anticancer activity and I intend to deep my scientific knowledge and exploring innovation and entrepreneur activities. Pedro José Moreira Sobral. Concluiu o(a) Mestrado integrado em Integrated Masters degree in Pharmaceutical Sciences em 2018/09/18 pelo(a) Universidade de Coimbra Faculdade de Farmácia. Frequenta o(a) Doutoramento em Doutoramento em Ciências Farmacêuticas pelo(a) Universidade de Coimbra Faculdade de Farmácia desde 2020. É Investigador no(a) Fundação para a Ciência e a Tecnologia. Publicou 4 artigos em revistas especializadas. Participou em 18 evento(s). Recebeu 4 prémio(s) e/ou homenagens. Participa e/ou participou como Bolseiro de Doutoramento em 1 projeto(s) e Bolseiro de Investigação em 1 projeto(s). Atua na(s) área(s) de Ciências Médicas e da Saúde e Ciências Exatas com ênfase em Química com ênfase em Química Orgânica. Nas suas atividades profissionais interagiu com 14 colaborador(es) em coautorias de trabalhos científicos.

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Identification

Personal identification

Full name: Pedro José Moreira Sobral
Date of birth: 1995/04/06
Gender: Male

Citation names

Pedro J. M. Sobral

Author identifiers

Ciência ID: 001B-EB58-C8B2
ORCID iD: 0000-0001-5202-4002
Researcher Id: F-9485-2019

Email addresses

pedrojmsobral@gmail.com (Professional)

Websites

www.linkedin.com/in/pedro-sobral-6882a6156 (Professional)

Knowledge fields

Medical and Health Sciences
Exact Sciences - Chemical Sciences - Organic Chemistry

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
French	Elementary (A2)	Elementary (A2)	Elementary (A2)	Elementary (A2)	Elementary (A2)
Spanish; Castilian	Elementary (A2)	Elementary (A2)	Elementary (A2)	Elementary (A2)	Elementary (A2)

Education

	Degree	Classification
2020 - 2024 Ongoing	Doutoramento em Ciências Farmacêuticas (Doutoramento) Major in Química Farmacêutica Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/02 - 2020/06 Concluded	Curso de Formação de Inglês do Quotidiano, nível Avançado II (Outros) Universidade de Coimbra, Portugal	18
2013/09/10 - 2018/09/18 Concluded	Integrated Masters degree in Pharmaceutical Sciences (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal "Internship Reports and Monograph entitled "Molecular Therapy in Neurodegenerative Diseases: rAAVs and Alzheimer's Disease" - Mark 18/20" (THESIS/DISSERTATION)	16
2010 - 2013 Concluded	Scientific-Humanistic course in Science and Technology (Ensino secundário) Escola Secundária da Infanta D. Maria, Portugal	17

Affiliation

Science

	Category Host institution	Employer
2021/07/01 - Current	Researcher (Research)	Fundação para a Ciência e a Tecnologia, Portugal

2018/11/19 - 2020/03/31	Researcher (Research)	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2020/09/01 - 2021/06/30	Invited Assistant (University Teacher)	Universidade de Coimbra Faculdade de Farmácia, Portugal

Others

	Category Host institution	Employer
2018/05/02 - 2018/07/31	Curricular Internship in Drug Regulatory Affairs	INFARMED, I.P., Portugal
	Direcção de Avaliação de Medicamentos - Unidade de Introdução no Mercado, Portugal
2018/01/08 - 2018/04/27	Curricular Internship in Community Pharmacy	Farmácia São Sebastião, Portugal

2017/07/03 - 2017/07/26	Extracurricular Internship in Community Pharmacy	Farmácia Estádio, Portugal

Projects

Grant

	Designation	Funders
2021/07/01 - Current	Preparation of novel fluorinated ent-kaurane-type diterpenoid derivatives and evaluation of their antiproliferative activity DFA/BD/4950/2020 PhD Student Fellow Universidade de Coimbra Faculdade de Farmácia, Portugal Universidade de Coimbra Centro de Química de Coimbra, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universitat Autònoma de Barcelona Departament de Bioquímica i Biologia Molecular, Spain	Fundação para a Ciência e a Tecnologia Ongoing
2018/11/19 - 2020/03/31	Small proteasome inhibitory molecules: a step forward in the discovery of antitumor drugs PTDC/QEQ-MED/7042/2014 Research Fellow Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Ongoing

Outputs

Publications

Conference abstract	Pedro J. M. Sobral. "Novel semisynthetic A-ring-cleaved glycyrrhetinic acid derivatives as potential anticancer agents". Paper presented in 15th National Organic Chemistry Meeting & 8th National Medicinal Chemistry Meeting, Faro, 2024. Published Pedro J. M. Sobral. "Synthesis and Cytotoxic Evaluation of Novel Madecassic Acid Derivatives". Paper presented in X Congresso Iberoamericano em Ciências Farmacêuticas, Coimbra, 2023. Published Pedro J. M. Sobral. "Síntese e Avaliação Citotóxica de Novos Derivados do Ácido Madecássico". Paper presented in 5º Encontro Nacional de Jovens Investigadores em Oncologia (5º ENJIO), Porto, 2023. Published Pedro J. M. Sobral. "Synthesis of novel madecassic acid derivatives and evaluation of their anticancer activity". Paper presented in 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting, Costa da Caparica, 2022. Published Pedro J. M. Sobral. "Novel A-ring cleaved glycyrrhetinic acid derivatives: Synthesis and evaluation of antiproliferative activity". Paper presented in The 7th International Electronic Conference on Medicinal Chemistry, 2021. Published Pedro J. M. Sobral. "Novel semisynthetic derivatives of madecassic acid as potential anticancer agents". Paper presented in ACS Fall 2021, Atlanta, 2021. Published Pedro J. M. Sobral. "Polyphenols as natural leads for drug discovery. Selective chemoenzymatic reactions.". Paper presented in IberPhenol - International Conference, Coimbra, 2020. Published Pedro J. M. Sobral. "Rutin and naringin as natural leads for drug discovery. Biocatalytic modifications to achieve novel bioactive compounds.". Paper presented in IberPhenol - International Conference, Coimbra, 2020. Published Pedro J. M. Sobral. "Novel Semisynthetic Derivatives of Madecassic Acid with Anticancer Activity". Paper presented in 13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT), Aveiro, 2020. Published Pedro J. M. Sobral. "Novel A-Ring Cleaved Glycyrrhetinic Acid Derivatives with Antiproliferative Activity". Paper presented in 13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT), Aveiro, 2020. Published
Conference poster	Pedro J. M. Sobral. "Novel semisynthetic A-ring-cleaved glycyrrhetinic acid derivatives as potential anticancer agents". Paper presented in 15th National Organic Chemistry Meeting & 8th National Medicinal Chemistry Meeting, 2024. Pedro J. M. Sobral. "Synthesis and Cytotoxic Evaluation of Novel Madecassic Acid Derivatives". Paper presented in X Congresso Iberoamericano em Ciências Farmacêuticas, 2023. Pedro J. M. Sobral. "Síntese e Avaliação Citotóxica de Novos Derivados do Ácido Madecássico". Paper presented in 5º Encontro Nacional de Jovens Investigadores em Oncologia (5º ENJIO), 2023. Pedro J. M. Sobral. "Synthesis of novel madecassic acid derivatives and evaluation of their anticancer activity". Paper presented in 14th National Organic Chemistry Meeting & 7th National Medicinal Chemistry Meeting, 2022. Pedro J. M. Sobral. "Novel A-ring cleaved glycyrrhetinic acid derivatives: Synthesis and evaluation of antiproliferative activity". Paper presented in The 7th International Electronic Conference on Medicinal Chemistry, 2021. Pedro J. M. Sobral. "Novel semisynthetic derivatives of madecassic acid as potential anticancer agents". Paper presented in ACS Fall 2021, 2021. Pedro J. M. Sobral. "Rutin and naringin as natural leads for drug discovery. Biocatalytic modifications to achieve novel bioactive compounds.". Paper presented in IberPhenol - International Conference, 2020. Pedro J. M. Sobral. "Novel A-Ring Cleaved Glycyrrhetinic Acid Derivatives with Antiproliferative Activity". Paper presented in 13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT), 2020. Pedro J. M. Sobral. "Novel Semisynthetic Derivatives of Madecassic Acid with Anticancer Activity". Paper presented in 13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT), 2020. Pedro J. M. Sobral. "Synthesis and Antiproliferative Activity of Novel A-Ring Cleaved Glycyrrhetinic Acid Derivatives". Paper presented in CIBB Meeting 2019, 2019. Pedro J. M. Sobral. "Madecassic Acid Derivatives as Potential Anticancer Agents: Synthesis and Cytotoxic Evaluation". Paper presented in CIBB Meeting 2019, 2019.
Journal article	Pedro J. M. Sobral. "Synthesis and Cytotoxic Evaluation of Novel Madecassic Acid Derivatives". Acta Farmacêutica Portuguesa - X Congresso Iberoamericano de Ciências Farmacêuticas (2023): https://actafarmaceuticaportuguesa.com/index.php/afp/issue/view/30. Published Pedro J. M. Sobral; Vicente, André T. S.; Salvador, Jorge A. R.. Corresponding author: Salvador, Jorge A. R.. "Recent advances in oridonin derivatives with anticancer activity". Frontiers in Chemistry 11 (2023): http://dx.doi.org/10.3389/fchem.2023.1066280. Published • 10.3389/fchem.2023.1066280 Judite RM Coimbra; Pedro J. M. Sobral; Armanda E Santos; Paula I. Moreira; Jorge AR Salvador. "An overview of glutaminyl cyclase inhibitors for Alzheimer's disease". Future Medicinal Chemistry 11 24 (2019): 3179-3194. https://doi.org/10.4155/fmc-2019-0163. Published • 10.4155/fmc-2019-0163 Balakrishna, Avula; Aguiar, António; Sobral, Pedro J. M.; Wani, Mohmmad Younus; Almeida e Silva, Joana; Sobral, Abilio J. F. N.. "Paal-Knorr synthesis of pyrroles: from conventional to green synthesis". Catalysis Reviews* 61 1 (2018): 84-110. http://dx.doi.org/10.1080/01614940.2018.1529932. Published • 10.1080/01614940.2018.1529932
Thesis / Dissertation	Pedro J. M. Sobral. "Internship Reports and Monograph entitled "Molecular Therapy in Neurodegenerative Diseases: rAAVs and Alzheimer's Disease" - Mark 18/20". Master, Universidade de Coimbra Faculdade de Farmácia, 2018. http://hdl.handle.net/10316/84380.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2020/01	Evaluation of the proteasomal inhibitory activity of the previously synthesized novel boronic acid derivatives	Group Meeting Faculdade de Farmácia da Universidade de Coimbra (Coimbra, Portugal)
2019/05	Chemical synthesis of the best previously designed novel boronic acid derivatives	Group Meeting Faculdade de Farmácia da Universidade de Coimbra (Coimbra, Portugal)
2019/01	Virtual library of novel boronic acid derivatives aiming to improve proteasomal inhibitory activity, selectivity, safety and pharmacokinetic properties	Group Meeting Faculdade de Farmácia da Universidade de Coimbra (Coimbra, Portugal)

Event participation

	Activity description Type of event	Event name Institution / Organization
2023 - 2033	Pharmaceutics - 3D and 4D Printing in Pharmaceutics Congress	Pharmaceutics - 3D and 4D Printing in Pharmaceutics Multidisciplinary Digital Publishing Institute AG, Switzerland
2024/01/22 - 2024/01/24	15th National Organic Chemistry Meeting (15ENQO) & 8th National Medicinal Chemistry Meeting (8ENQT) Conference	15th National Organic Chemistry Meeting & 8th National Medicinal Chemistry Meeting Sociedade Portuguesa de Química, Portugal
2023/10/26 - 2023/10/28	X Congresso Iberoamericano em Ciências Farmacêuticas Congress	X Congresso Iberoamericano em Ciências Farmacêuticas
2023/09/22 - 2023/09/22	5º Encontro Nacional de Jovens Investigadores em Oncologia (5º ENJIO) Conference	5º Encontro Nacional de Jovens Investigadores em Oncologia (5º ENJIO) Liga Portuguesa Contra o Cancro Núcleo Regional do Norte, Portugal
2022/04/20 - 2022/04/22	14th National Organic Chemistry Meeting (14ENQO) and the 7th National Medicinal Chemistry Meeting (7ENQT) Congress	14th National Organic Chemistry Meeting (14ENQO) and the 7th National Medicinal Chemistry Meeting (7ENQT) Sociedade Portuguesa de Química, Portugal
2021/11/01 - 2021/11/30	The 7th International Electronic Conference on Medicinal Chemistry (ECMC 2021) Conference	The 7th International Electronic Conference on Medicinal Chemistry (ECMC 2021)
2020/01/15 - 2020/01/17	13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT) Congress	13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT) Sociedade Portuguesa de Química, Portugal
2020 - 2020	IberPhenol - International Conference (Abstracts accepted, Conference postponed due to Covid-19 pandemic) Conference	IberPhenol - International Conference Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/12/19 - 2019/12/20	CIBB Meeting 2019 Congress	CIBB Meeting 2019 Centre for Innovative Biomedicine and Biotechnology (CIBB), Portugal
2019/11/15 - 2019/11/15	1st Annual Meeting in Pharmaceutical Sciences Congress	1st Annual Meeting in Pharmaceutical Sciences Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/10/04 - 2019/10/04	Researcher Academy On Campus - "How to Get Published" Seminar	Researcher Academy On Campus - "How to Get Published" Elsevier Inc, United States
2019/09/12 - 2019/09/12	Web of Science Training Seminar	Web of Science Training Clarivate Analytics Inc, United States Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2018/10/26 - 2018/10/26	Cancro: A Intervenção do Farmacêutico Seminar	Cancro: A Intervenção do Farmacêutico Liga Portuguesa Contra o Cancro Núcleo Regional do Centro, Portugal
2018/09/27 - 2018/09/28	First Drugs R&D PhD Symposium - Translational Science: From Academia to Industry Congress	First Drugs R&D PhD Symposium - Translational Science: From Academia to Industry Universidade de Coimbra, Portugal
2018/01/03 - 2018/01/05	PharmCareer 2018 Congress	PharmCareer 2018 Núcleo de Estudantes de Farmácia, Faculdade de Farmácia da Universidade de Coimbra, Portugal
2017/12/18 - 2017/12/18	Formação SIFARMA Seminar	Formação SIFARMA Núcleo de Estudantes de Farmácia, Faculdade de Farmácia da Universidade de Coimbra, Portugal
2016/11/10 - 2016/11/11	X Congresso Científico do NEF/AAC - Doenças Raras & Medicamentos Órfãos - Acesso À Inovação Terapêutica Congress	X Congresso Científico do NEF/AAC- Doenças Raras & Medicamentos Órfãos – Acesso À Inovação Terapêutica Núcleo de Estudantes de Farmácia, Faculdade de Farmácia da Universidade de Coimbra, Portugal
2013/06/21 - 2013/06/26	Trainee in Chemical Engineering Workshop	5ª Edição da Universidade de Verão da Universidade de Coimbra Universidade de Coimbra, Portugal

Association member

	Society Organization name	Role
2020/07 - Current	Group for the Promotion of Pharmaceutical chemistry in Academia (GP2A)	Portuguese National Point of Contact (NPC)
2019/11/02 - Current	Sociedade Portuguesa de Química (SPQ)	Nº de Sócio Activo - 6089

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2021/02/01 - 2021/08/01	Química Farmacêutica II	Mestrado Integrado em Ciências Farmacêuticas (Mestrado integrado)	Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/02/01 - 2021/08/01	Toxicologia e Análises Toxicológicas	Mestrado Integrado em Ciências Farmacêuticas (Mestrado integrado)	Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/02/01 - 2021/08/01	Química Orgânica e Biomolecular	Licenciatura em Farmácia Biomédica (Licenciatura)	Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/09/01 - 2021/02/01	Metodologias Laboratoriais	Licenciatura em Ciências Bioanalíticas (Licenciatura)	Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/09/01 - 2021/02/01	Química Biorgânica	Licenciatura em Ciências Bioanalíticas (Licenciatura)	Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/09/01 - 2021/02/01	Química Orgânica II	Mestrado Integrado em Ciências Farmacêuticas (Mestrado integrado)	Universidade de Coimbra Faculdade de Farmácia, Portugal

Journal scientific committee

	Journal title (ISSN)	Publisher
2024/02/25 - 2024/02/25	Ecotoxicology and Environmental Safety (1090-2414)	Elsevier
2024/02/22 - 2024/02/22	Heliyon (2405-8440)	Elsevier
2024/02/10 - 2024/02/10	Heliyon (2405-8440)	Elsevier
2024/02/03 - 2024/02/03	Materials Science and Engineering: B (1873-4944)	Elsevier
2023/09/19 - 2023/09/19	Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (1873-3557)	Elsevier
2023/05/24 - 2023/05/24	Polycyclic Aromatic Compounds (1563-5333)	Taylor & Francis
2023/02/22 - 2023/02/22	Inorganic Chemistry Communications (1879-0259)	Elsevier

Mentoring / Tutoring

	Topic	Student name
2022/05 - 2022/07	Co-orientation of Integrated Master's Degree students of Pharmaceutical Sciences on Curricular Internship	Integrated Master's Degree students of Pharmaceutical Sciences
2021/09 - 2022/02	Co-orientation of Erasmus+ Students	Erasmus+ Students
2020/02 - 2020/05	Co-orientation of Integrated Master's Degree students of Pharmaceutical Sciences on Curricular Internship	Integrated Master's Degree students of Pharmaceutical Sciences
2019/02 - 2019/05	Co-orientation of Integrated Master's Degree students of Pharmaceutical Sciences on Curricular Intership	Integrated Master's Degree students of Pharmaceutical Sciences

Distinctions

Award

2024	15th National Organic Chemistry Meeting (15ENQO) & 8th National Medicinal Chemistry Meeting (8ENQT) Flash Poster Presentation Award Sociedade Portuguesa de Química, Portugal
2023	X Congresso Iberoamericano em Ciências Farmacêuticas Best Pharmaceutical Chemistry Poster Award Universidade de Coimbra Faculdade de Farmácia, Portugal
2021	ECMC-7 Best Poster Award Multidisciplinary Digital Publishing Institute AG, Switzerland
2014	The 3% Best Students Award Universidade de Coimbra, Portugal