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I am a creative scientist and freelance writer and science communicator with over 12 years of professional experience in science. My expertise is in immunology and infectious diseases, including molecular and cell biology, cell signalling and drug development. My skills are based on scientific curation, information gathering, writing, editing and proofreading a wide range of communication materials including feature articles, website content, reports, newsletters, media content and fact sheets. My strengths include infectious disease pathophysiology, molecular biology approaches, high content and high throughput screening, experimental design, scientific methodology, in vivo studies and cell-based approaches. I also have creative thinking in solving scientific problems, motivation and science-based solutions. During my scientific career I have worked for a wide range of clients including biotech companies, healthcare companies, science companies and as a volunteer for a non-governmental agencie. I am currently a postdoctoral researcher at the Centre for Neuroscience and Cell Biology (CNC) studying primary immunodeficiencies using direct cell reprogramming to investigate dendritic cell deficiency. I also work as a freelance scientific writer.
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Identification

Personal identification

Full name
Lavinia Maria Dal Mas Romera

Citation names

  • Romera, Lavinia
  • Romera, L.M.D.

Author identifiers

Ciência ID
0017-EFAA-C7DA
ORCID iD
0000-0002-9625-0615

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Medical and Health Sciences - Health Sciences - Infectious Diseases
  • Social Sciences - Media and Communications

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Upper intermediate (B2)
Education
Degree Classification
2012/09/01 - 2016/12/02
Concluded
 Pathophysiology (Doctor of Philosophy)
Major in Pharmacy, Immunology
Universidade de São Paulo, Brazil
"Characterization of the interrelationship between Notch and toll-like receptor signaling pathways in experimental paracoccidioidomycosis" (THESIS/DISSERTATION)
 A
2010/02/01 - 2012/08/20
Concluded
 Clinical Analysis (Master)
Major in Cellular Immunology and Medical Mycology
Universidade de São Paulo, Brazil
"Analysis of the interaction between Paracoccidioides brasiliensis and macrophages through Notch-like receptors" (THESIS/DISSERTATION)
 A
2006/02/01 - 2009/12/01
Concluded
 Pharmaceutical Sciences (Bachelor)
Major in Pharmacy
Universidade Anhanguera de São Paulo Santo André - Unidade 3, Brazil
 A
Affiliation

Science

Category
Host institution 		Employer
2021/10/01 - Current Postdoc (Research) Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
Biocant Associação de Transferência de Tecnologia, Portugal
2019/10/01 - 2020/10 Postdoc (Research) Drugs for Neglected Diseases initiative, Switzerland
Universidade de São Paulo, Brazil
(...)
2018/02/01 - 2019/02/28 Postdoc (Research) Universidade Federal de São Paulo, Brazil
Universidade Federal de São Paulo, Brazil
2017/02/01 - 2019/02/28 Postdoc (Research) Universidade de São Paulo, Brazil
Universidade de São Paulo, Brazil
(...)

Teaching in Higher Education

Category
Host institution 		Employer
2019/09/01 - 2019/10/01 Associate Professor (University Teacher) Centro Universitário das Faculdades Metropolitanas Unidas, Brazil
Centro Universitário das Faculdades Metropolitanas Unidas, Brazil

Other Careers

Category
Host institution 		Employer
2018/12/01 - 2019/12/01 Técnico Farmacêutico Especialista Principal (Técnico Farmacêutico) Droga Bueno, Brazil
Droga Bueno, Brazil

Others

Category
Host institution 		Employer
2021/02/01 - Current Freelance Scientific Consulting and Writing PreScouter, United States
Projects

Grant

Designation Funders
2012/09/01 - 2016/12/31 Characterization of the interrelationship between notch and tlr signaling pathways in experimental paracoccidioidomycosis
12/14955-0
PhD Student Fellow
Universidade de São Paulo/Faculdade de Ciências Farmacêuticas, Brazil
 Fundação de Amparo à Pesquisa do Estado de São Paulo
Concluded
2010/02/01 - 2012/08/31 Analysis of the interaction between Paracoccidioides brasiliensis and macrophages through Notch-like receptors
10/03616-4
Master Student Fellow
Universidade de São Paulo/Faculdade de Ciências Farmacêuticas, Brazil
 Fundação de Amparo à Pesquisa do Estado de São Paulo
Concluded
2009/02/01 - 2009/12/31 Analysis of Notch ligand gene expression in dendritic cells after interaction with Paracoccidioides brasiliensis
08/58799-6
Scientific Initiation Fellow
Universidade de São Paulo/Faculdade de Ciências Farmacêuticas, Brazil
 Fundação de Amparo à Pesquisa do Estado de São Paulo
Concluded

Contract

Designation Funders
2023/03/01 - 2026/02/28 Using dendritic cell reprogramming to identify novel therapy targets.
2022.02338.PTDC
Co-Principal Investigator (Co-PI)
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/10/01 - 2023/10/31 DiverDC: Understanding dendritic cell diversity with cell reprogramming
PTDC/MED-IMU/4520/2020
Post-doc
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Journal article
  1. Alison Felipe Alencar Chaves; Patricia Xander; Lavínia Maria Dal’Mas Romera; Fernando Luiz Affonso Fonseca; Wagner Luiz Batista. "What is the elephant in the room when considering new therapies for fungal diseases?". Critical Reviews in Microbiology (2021): 1-15. https://doi.org/10.1080/1040841X.2021.1876632.
    10.1080/1040841X.2021.1876632
  2. "The translational challenge in Chagas disease drug development". Memórias do Instituto Oswaldo Cruz (2021): https://memorias.ioc.fiocruz.br/article/10809/0501-chagas-the-translational-challenge-in-chagas-disease-drug-development.
    10.1590/0074-02760200501
  3. Romera, Lavinia. "New Biomarker in Chagas Disease: Extracellular Vesicles Isolated from Peripheral Blood in Chronic Chagas Disease Patients Modulate the Human Immune Response.". Journal of immunology research (2021): https://europepmc.org/articles/PMC7815414.
    10.1155/2021/6650670
  4. Romera, Lavinia. "Insulin Modulates Inflammatory Cytokine Release in Acute Stages and Augments Expression of Adhesion Molecules and Leukocytes in Lungs on Chronic Stages of Paracoccidioidomycosis.". Frontiers in immunology (2020): https://europepmc.org/articles/PMC7708333.
    10.3389/fimmu.2020.583385
  5. Franco, C.H.; Warhurst, D.C.; Bhattacharyya, T.; Au, H.Y.A.; Le, H.; Giardini, M.A.; Pascoalino, B.S.; et al. "Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity". International Journal for Parasitology: Drugs and Drug Resistance 13 (2020): 107-120. http://www.scopus.com/inward/record.url?eid=2-s2.0-85087935048&partnerID=MN8TOARS.
    10.1016/j.ijpddr.2020.06.001
  6. Kimura, T.F.E.; Romera, L.M.D.M.; de Almeida, S.R.. "Fonsecaea pedrosoi Conidia Induces Activation of Dendritic Cells and Increases CD11c+ Cells in Regional Lymph Nodes During Experimental Chromoblastomycosis". Mycopathologia (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85078883457&partnerID=MN8TOARS.
    10.1007/s11046-020-00429-w
  7. Jannuzzi, G.P.; de Almeida, J.R.F.; Amarante-Mendes, G.P.; Romera, L.M.D.; Kaihami, G.H.; Vasconcelos, J.R.; Ferreira, C.P.; de Almeida, S.R.; Ferreira, K.S.. "TLR3 is a negative regulator of immune responses against Paracoccidioides brasiliensis". Frontiers in Cellular and Infection Microbiology 9 JAN (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85060579456&partnerID=MN8TOARS.
    10.3389/fcimb.2018.00426
  8. Casagrande, F.B.; de Souza Ferreira, S.; Nunes, F.P.B.; Romera, L.M.D.; dos Santos, S.S.; Tessaro, F.H.G.; de Souza, P.R.K.; Almeida, S.R.; Martins, J.O.. "Insulin modulates Paracoccidioides brasiliensis-induced inflammation by restoring the populations of NK cells, dendritic cells, and B lymphocytes in lungs". Journal of Diabetes Research 2018 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85056508077&partnerID=MN8TOARS.
    10.1155/2018/6209694
  9. Dal'Mas Romera, Lavinia Maria; Kaihami, Gilberto Hideo; Jannuzzi, Grasielle Pereira; Fogaca de Almeida, Jose Roberto; de Almeida, Sandro Rogerio. "The Critical Role of Notch1-TLR 4 Signaling in the Inflammatory and Fungicidal Activity of Macrophages Against Paracoccidioides brasiliensis Strain Pb18". Mycopathologia 182 9-10 (2017): 797-807. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000409494400003&KeyUID=WOS:000409494400003.
    10.1007/s11046-017-0154-4
Preprint
  1. "Discovery of clinically approved drugs capable of inhibiting SARS-CoV-2 in vitro infection using a phenotypic screening strategy and network-analysis to predict their potential to treat covid-19". 2020. http://dx.doi.org/10.1101/2020.07.09.196337.
    10.1101/2020.07.09.196337
Thesis / Dissertation
  1. Lavínia Maria Dal'Mas Romera. "Caracterização da inter-relação entre as vias de sinalização Notch e TLR na paracoccidioidomicose experimental". PhD, 2016. https://doi.org/10.11606/T.9.2017.tde-22122016-113633.
    https://doi.org/10.11606/T.9.2017.tde-22122016-113633
  2. Lavínia Maria Dal'Mas Romera. "Análise da interação entre Paracoccidioides brasiliensis e macrófagos através de receptores de tipo Notch". Master, 2012. https://doi.org/10.11606/D.9.2012.tde-10092012-111532.
    https://doi.org/10.11606/D.9.2012.tde-10092012-111532
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/02 EVs isolated from trypomastigotes forms by Trypanosoma cruzi are a new therapy tocontrol parasitemia in the experimental model of Chagas disease. ISEV workshop
International Society of Extracellular Vesicles (Buenos Aires, Argentina)
2020/03/01 EVs isolated from trypomastigotes forms by Trypanosoma cruzi are a new therapy tocontrol parasitemia in the experimental model of Chagas disease. ISEV workshop
ISEV (Buenos Aires, Argentina)
2015/09/05 Importance of Notch-TLRsignalling in experimental paracoccidioidomycosis. 19th Congress of International Society for human and animal mycology - ISHAM
ISHAM (Melbourne, Australia)
2015/08/06 Notch-TLR signalling as an escape mechanism inparacoccidioidomycosis. Week of Pharmacy at the University of São Paulo
Faculdade de Ciências Farmacêuticas - USP (São Paulo, Brazil)
2013/10/03 Cell signalling and innate immune response. Week of Biomedicine
Universidade de São Lourenço (São Lourenço, Brazil)
2011/08/05 Signalling pathway in the innate immune response. Week of pharmacy
Universidade do Grande ABC (Santo André)

Ad Hoc journal article review

Journal title (ISSN) Publisher
2019/01/01 - Current International Journal of Immunology (2372-0948)

Association member

Society Organization name Role
2019/01/01 - 2020/01/01 International Society for Extracellular Vesicles.

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019/09/01 - 2019/10/31 Clinical Analysis, Toxicology and Pharmaceutical care Biomedicine and Pharmaceutical Sciences (Bachelor) Centro Universitário das Faculdades Metropolitanas Unidas, Brazil

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2023/03/02 - 2023/03/23 Curricular assessment and interviews with the candidates.
Evaluator
 Universidade de Coimbra, Portugal
2023/03/02 - 2023/03/23 Curricular assessment and interviews with the candidates for a postdoctoral position.
Evaluator
 Universidade de Coimbra, Portugal