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PharmD by FFUL (2001). MSc in Regulation and Evaluation of Medicines and Health Products by FFUL (2006). PhD in Pharmacy (Pharmacology) by the Universidade de Lisboa (2008). Habilitation in Pharmacy (Pharmacology and Pharmacotherapy) by the Universidade de Lisboa (2014). MPH by the Bloomberg School of Public Health of the Johns Hopkins University (2020). Specialist in Regulatory Affairs by the Portuguese Pharmaceutical Society. Member of the Pedagogical Council, of the School Council and President of the Ethics Committee for Research with Human Beings of FFUL. Vice-Chair of the Committee for Medicinal Products for Human use (CHMP) at the European Medicines Agency.
Identificação

Identificação pessoal

Nome completo
Bruno Miguel Nogueira Sepodes

Nomes de citação

  • Sepodes, Bruno
  • Bruno Sepodes
  • B. Sepodes
  • B.M.N. Sepodes

Identificadores de autor

Ciência ID
F312-4140-7A60
ORCID iD
0000-0002-2761-0955

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Português (Idioma materno)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2020
Concluído
Master of Public Health (MPH) (Master Universitario)
Johns Hopkins University Bloomberg School of Public Health, Estados Unidos
2014
Concluído
n/a (Título de Agregado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"n/a" (TESE/DISSERTAÇÃO)
2008
Concluído
Doutoramento em Farmácia (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Modulação Farmacológica da Lesão Induzida por Isquémia-Reperfusão Hepática" (TESE/DISSERTAÇÃO)
2008
Concluído
Farmácia (Doutoramento)
Especialização em Especialidade: Farmacologia
Universidade de Lisboa, Portugal
"Modulação Farmacológica da Lesão Induzida por Isquémia - Reperfusão Hepática" (TESE/DISSERTAÇÃO)
2006
Concluído
Mestrado em Regulação e Avaliação do Medicamento e Produtos de Saúde (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
""Contribuição para o desenvolvimento não-clínico do Tempol como novo fármaco anti-inflamatório"" (TESE/DISSERTAÇÃO)
2001
Concluído
Licenciatura em Ciências Farmacêuticas (Licenciatura)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"n.a." (TESE/DISSERTAÇÃO)
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2021/12/07 - Atual Professor Catedrático (Docente Universitário) Universidade de Lisboa, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020/10/01 - 2021/12/06 Professor Associado (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal
2008 - 2020 Professor Auxiliar (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal
2016 - 2019 Professor Auxiliar (Docente Universitário) Universidade de Lisboa, Portugal
2006 - 2008 Assistente (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal
2005 - 2006 Assistente Estagiário (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal
2003 - 2005 Monitor (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2019 - 2022 Membro do Conselho de Escola Universidade de Lisboa, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - 2022 Conselho Pedagógico Universidade de Lisboa, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 - 2019 Conselho geral ou orgão correspondente Universidade de Lisboa, Portugal
2017 - 2019 Conselho pedagógico Universidade de Lisboa, Portugal
2013 - 2016 Conselho pedagógico Universidade de Lisboa Faculdade de Farmácia, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2018/10 - Atual Vice-Presidente (Vice-Chair) do Comité dos Medicamentos de Uso Humano (CHMP) European Medicines Agency, Países Baixos
2013 - Atual Membro do Comité de Terapias Avançadas (CAT) European Medicines Agency, Países Baixos
2012 - Atual Membro do Comité dos Medicamentos de Uso Humano (CHMP) European Medicines Agency, Países Baixos
2018 - 2020 Membro do Comité dos Medicamentos Órfãos (COMP) European Medicines Agency, Países Baixos
2012/09 - 2018/09 Presidente do Comité dos Medicamentos Órfãos (COMP) European Medicines Agency, Países Baixos
2008 - 2012 Membro do Comité dos Medicamentos Órfãos (COMP) European Medicines Agency, Países Baixos
Produções

Publicações

Artigo em conferência
  1. Edite Teixeira de Lemos; Flávio Reis; Lina Carvalho; Natércia Teixeira; Alice Santos Silva; Georgina Correia da Silva; Petronila Rocha Pereira; et al. "O exercício físico como modulador positive dos factores de risco cardiovascular- acção cardiometabólica, antioxidante e anti-inflamatória.". 2008.
Artigo em revista
  1. "A review of the continuous professional development system for pharmacists". Human Resources for Health 20 1 (2022): http://dx.doi.org/10.1186/s12960-021-00700-1.
    10.1186/s12960-021-00700-1
  2. Joaquim Bié; Bruno Sepodes; Pedro C. B. Fernandes; Maria H. L. Ribeiro. "Enzyme Immobilization and Co-Immobilization: Main Framework, Advances and Some Applications". Processes (2022): https://doi.org/10.3390/pr10030494.
    10.3390/pr10030494
  3. Joana Mota; Rosa Direito; João Rocha; João Fernandes; Bruno Sepodes; Maria Eduardo Figueira; Anabela Raymundo; Ana Lima; Ricardo Boavida Ferreira. "Lupinus albus Protein Components Inhibit MMP-2 and MMP-9 Gelatinolytic Activity In Vitro and In Vivo". International Journal of Molecular Sciences (2021): https://doi.org/10.3390/ijms222413286.
    10.3390/ijms222413286
  4. Rafael Amaral; Carla Torre; João Rocha; Bruno Sepodes. "Ebola outbreaks: A stress test of the preparedness of medicines regulatory systems for public health crises". Drug Discovery Today (2021): https://doi.org/10.1016/j.drudis.2021.06.019.
    10.1016/j.drudis.2021.06.019
  5. Rosa Direito; João Rocha; Bruno Sepodes; Maria Eduardo-Figueira. "From Diospyros kaki L. (Persimmon) Phytochemical Profile and Health Impact to New Product Perspectives and Waste Valorization". Nutrients (2021): https://doi.org/10.3390/nu13093283.
    10.3390/nu13093283
  6. Paula Viana; Leonor Meisel; Ana Lopes; Rosário de Jesus; Georgina Sarmento; Sofia Duarte; Bruno Sepodes; et al. "Identification of Antibiotics in Surface-Groundwater. A Tool towards the Ecopharmacovigilance Approach: A Portuguese Case-Study". Antibiotics 10 8 (2021): 888-888. https://doi.org/10.3390/antibiotics10080888.
    10.3390/antibiotics10080888
  7. "Improvement of wheat cookies’ nutritional quality, by partial substitution with common bean and maize flours, sustained human glycemia and enhanced satiety perception". Cereal Chemistry (2021): http://dx.doi.org/10.1002/cche.10460.
    10.1002/cche.10460
  8. Rosa Direito; João Rocha; Bruno Sepodes; Maria Eduardo-Figueira. "Phenolic Compounds Impact on Rheumatoid Arthritis, Inflammatory Bowel Disease and Microbiota Modulation". Pharmaceutics 13 2 (2021): 145-145. https://doi.org/10.3390/pharmaceutics13020145.
    10.3390/pharmaceutics13020145
  9. Grácio, Madalena; Rocha, João; Pinto, Rui; Boavida Ferreira, Ricardo; Solas, João; Eduardo-Figueira, Maria; Sepodes, Bruno; Ribeiro, Ana Cristina. "A proposed lectin-mediated mechanism to explain the in Vivo antihyperglycemic activity of ¿-conglutin from Lupinus albus seeds". (2021): http://hdl.handle.net/10400.21/13866.
    10.1002/fsn3.2520
  10. Carvalho, Marta; Sepodes, Bruno; Martins, Ana Paula. "Patient access to gene therapy medicinal products : a comprehensive review". (2021): http://hdl.handle.net/10451/46388.
    10.1136/bmjinnov-2020-000425
  11. Mota, Joana; Direito, Rosa; Rocha, João; Fernandes, João; Sepodes, Bruno; Figueira, Maria Eduardo; Raymundo, Anabela; Lima, Ana; Ferreira, Ricardo Boavida. "Lupinus albus protein componentes inhibit MMP-2 and MMP-9 gelatinolytic activity in vitro and in vivo". (2021): http://hdl.handle.net/10400.5/22755.
  12. Mota, Joana; Direito, Rosa; Rocha, João; Fernandes, João; Sepodes, Bruno; Figueira, Maria Eduardo; Raymundo, Anabela; Lima, Ana; Ferreira, Ricardo Boavida. "Lupinus albus protein componentes inhibit MMP-2 and MMP-9 gelatinolytic activity in vitro and in vivo". (2021): http://hdl.handle.net/10400.5/22755.
  13. Carvalho, Marta; Sepodes, Bruno; Martins, Ana Paula. "Patient access to gene therapy medicinal products : a comprehensive review". (2021): http://hdl.handle.net/10451/46388.
    10.1136/bmjinnov-2020-000425
  14. Sepodes, Bruno. "The translational value of animal models in orphan medicines designations for rare paediatric neurological diseases". Regulatory Toxicology and Pharmacology 118 (2020): 104810-104810. http://dx.doi.org/10.1016/j.yrtph.2020.104810.
    10.1016/j.yrtph.2020.104810
  15. João Rocha; Raquel Leandro; Rosa Direito; Margarida Gonçalves; Maria Paula Duarte; Adelaide Fernandes; Bruno Sepodes; Maria-Eduardo Figueira. "Attenuation of Colonic Injury and Inflammation by Administration of a Phenolic Extract of Summer Savory (Satureja hortensis L.) in Experimental Inflammatory Bowel Disease in Mice". Applied Sciences 10 23 (2020): 8465-8465. https://doi.org/10.3390/app10238465.
    10.3390/app10238465
  16. Sepodes, Bruno. "Patient access to gene therapy medicinal products: a comprehensive review". BMJ Innovations (2020): bmjinnov--2020--0004-bmjinnov--2020--0004. http://dx.doi.org/10.1136/bmjinnov-2020-000425.
    10.1136/bmjinnov-2020-000425
  17. Segundo Mariz; Kerstin Westermark; Bruno Sepodes. "Designation of orphan conditions in Europe: regulatory observations and considerations after implementation of regulation 141/2000". Expert Opinion on Orphan Drugs (2020): 1-7. https://doi.org/10.1080/21678707.2020.1784720.
    10.1080/21678707.2020.1784720
  18. Eichler HG; Cavaleri M; Enzmann H; Scotti F; Sepodes B; Sweeney F; Vamvakas S; Rasi G. "Clinical trials for Covid-19: can we better use the short window of opportunity?". Clinical pharmacology and therapeutics (2020): http://europepmc.org/abstract/med/32407539.
    10.1002/cpt.1891
  19. Rocha, João; Leandro, Raquel; Direito, Rosa; Gonçalves, Margarida; Duarte, Maria Paula; Fernandes, Adelaide; Sepodes, Bruno; Figueira, Maria Eduardo. "Attenuation of colonic injury and inflammation by administration of a phenolic extract of summer savory (Satureja hortensis l.) in experimental inflammatory bowel disease in mice". (2020): http://hdl.handle.net/10362/114530.
    https://doi.org/10.3390/app10238465
  20. Rocha, João; Leandro, Raquel; Direito, Rosa; Gonçalves, Margarida; Duarte, Maria Paula; Fernandes, Adelaide; Sepodes, Bruno; Figueira, Maria Eduardo. "Attenuation of colonic injury and inflammation by administration of a phenolic extract of summer savory (Satureja hortensis l.) in experimental inflammatory bowel disease in mice". (2020): http://hdl.handle.net/10362/114530.
    https://doi.org/10.3390/app10238465
  21. Sheean ME; Malikova E; Duarte D; Capovilla G; Fregonese L; Hofer M; Magrelli A; et al. "Nonclinical data supporting orphan medicinal product designations in the area of rare infectious diseases.". Drug discovery today (2019): http://europepmc.org/abstract/med/31704277.
    10.1016/j.drudis.2019.10.015
  22. Sepodes, Bruno. "Are Novel, Nonrandomized Analytic Methods Fit for Decision Making? The Need for Prospective, Controlled, and Transparent Validation.". Clinical pharmacology and therapeutics (2019): https://doi.org/10.1002/cpt.1638.
    10.1002/cpt.1638
  23. Rosa Direito; João Rocha; Ana-Teresa Serra; Adelaide Fernandes; Marisa Freitas; Eduarda Fernandes; Rui Pinto; et al. "Anti-inflammatory Effects of Persimmon (Diospyros kaki L.) in Experimental Rodent Rheumatoid Arthritis". Journal of Dietary Supplements (2019): https://doi.org/10.1080/19390211.2019.1645256.
    10.1080/19390211.2019.1645256
  24. Rosa Direito; Catarina Reis; Luís Roque; Margarida Gonçalves; Ana Sanches-Silva; Maria Manuela Gaspar; Rui Pinto; et al. "Phytosomes with Persimmon (Diospyros kaki L.) Extract: Preparation and Preliminary Demonstration of In Vivo Tolerability". Pharmaceutics (2019): https://doi.org/10.3390/pharmaceutics11060296.
    10.3390/pharmaceutics11060296
  25. João Rocha; Ana Lima; Maria Margarida Gonçalves; Maria Paula Duarte; Vanessa Mateus; Catarina Sousa; Adelaide Fernandes; et al. "Reduction of Inflammation and Colon Injury by a Spearmint Phenolic Extract in Experimental Bowel Disease in Mice". Medicines (2019): https://www.mdpi.com/2305-6320/6/2/65.
    10.3390/medicines6020065
  26. Borg, J.-J.; Melchiorri, D.; Sepodes, B.; Caramella, C.M.; Tomino, C.; Micallef, B.; Serracino-Inglott, A.; Nistico, R.. "Optimising bench science to withstand regulatory scrutiny". Pharmacological Research 139 (2019): 491-493. http://www.scopus.com/inward/record.url?eid=2-s2.0-85055581024&partnerID=MN8TOARS.
    10.1016/j.phrs.2018.10.014
  27. O’Connor, D.J.; Sheean, M.E.; Hofer, M.P.; Tsigkos, S.; Mariz, S.; Fregonese, L.; Larsson, K.; et al. "Defining orphan conditions in the context of the European orphan regulation: challenges and evolution". Nature Reviews Drug Discovery (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85063584936&partnerID=MN8TOARS.
    10.1038/nrd.2018.128
  28. Carvalho, M.; Martins, A.P.; Sepodes, B.. "Hurdles in gene therapy regulatory approval: a retrospective analysis of European Marketing Authorization Applications". Drug Discovery Today 24 3 (2019): 823-828. http://www.scopus.com/inward/record.url?eid=2-s2.0-85059141441&partnerID=MN8TOARS.
    10.1016/j.drudis.2018.12.007
  29. Mendes, C.; Rocha, J.; Direito, R.; Fernandes, A.; Sepodes, B.; Figueira, M.-E.; Ribeiro, M.H.. "Anti-inflammatory activity of grapefruit juice in an in vivo model of ulcerative colitis: Comparability studies of unprocessed and bioprocessed juices". Journal of Functional Foods 63 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85072299230&partnerID=MN8TOARS.
    10.1016/j.jff.2019.103564
  30. Rocha, J.; Direito, R.; Lima, A.; Mota, J.; Gonçalves, M.; Duarte, M.P.; Solas, J.; et al. "Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in experimental inflammatory bowel disease in mice". Biomedicine and Pharmacotherapy 118 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85070874907&partnerID=MN8TOARS.
    10.1016/j.biopha.2019.109351
  31. Sepodes, Bruno. "The Challenges of the European Medicines Evaluation by 2025". (2019): http://revista.farmacoterapia.pt/index.php/rpf/article/view/227.
    10.25756/rpf.v11i2-3.220
  32. Direito, Rosa; Rocha, João; Lima, Ana; Gonçalves, Maria Margarida Boavida Pontes; Duarte, Maria Paula Amaro de Castilho; Mateus, Vanessa; Sousa, Catarina; et al. "Reduction of Inflammation and Colon Injury by a Spearmint Phenolic Extract in Experimental Bowel Disease in Mice". (2019): http://hdl.handle.net/10362/97775.
    https://doi.org/10.3390/medicines6020065
  33. Rocha, João; Direito, Rosa; Lima, Ana; Mota, Joana; Gonçalves, Margarida; Duarte, Maria Paula; Solas, João; et al. "Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in experimental inflammatory bowel disease in mice". (2019): http://hdl.handle.net/10400.21/10733.
    10.1016/j.biopha.2019.109351
  34. Rocha, João; Direito, Rosa; Lima, Ana; Mota, Joana; Gonçalves, Margarida; Duarte, Maria Paula; Solas, João; et al. "Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in experimental inflammatory bowel disease in mice". (2019): http://hdl.handle.net/10400.5/18269.
    https://doi.org/10.1016/j.biopha.2019.109351
  35. Rocha, João; Direito, Rosa; Lima, Ana; Mota, Joana; Gonçalves, Margarida; Duarte, Maria Paula; Solas, João; et al. "Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in experimental inflammatory bowel disease in mice". (2019): http://hdl.handle.net/10400.21/10733.
    10.1016/j.biopha.2019.109351
  36. Direito, Rosa; Rocha, João; Lima, Ana; Gonçalves, Maria Margarida Boavida Pontes; Duarte, Maria Paula Amaro de Castilho; Mateus, Vanessa; Sousa, Catarina; et al. "Reduction of Inflammation and Colon Injury by a Spearmint Phenolic Extract in Experimental Bowel Disease in Mice". (2019): http://hdl.handle.net/10362/97775.
    https://doi.org/10.3390/medicines6020065
  37. Rocha, João; Direito, Rosa; Lima, Ana; Mota, Joana; Gonçalves, Margarida; Duarte, Maria Paula; Solas, João; et al. "Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in experimental inflammatory bowel disease in mice". (2019): http://hdl.handle.net/10400.5/18269.
    https://doi.org/10.1016/j.biopha.2019.109351
  38. Sepodes, Bruno. "The Challenges of the European Medicines Evaluation by 2025". (2019): http://revista.farmacoterapia.pt/index.php/rpf/article/view/227.
    10.25756/rpf.v11i2-3.220
  39. Andrea Ecker; Segundo Mariz; Frauke Naumann-Winter; Koenraad Norga; Ingeborg Barisic; Thomas Girard; Paolo Tomasi; Dirk Mentzer; Bruno Sepodes. "Comparative analysis of the scope of European Union paediatric investigation plans with corresponding orphan designations". Archives of Disease in Childhood 103 5 (2018): 427-430. https://doi.org/10.1136/archdischild-2017-313352.
    10.1136/archdischild-2017-313352
  40. Mateus, V.; Rocha, J.; Mota-Filipe, H.; Sepodes, B.; Pinto, R.. "Hemin reduces inflammation associated with TNBS-induced colitis". Clinical and Experimental Gastroenterology 11 (2018): 325-334. http://www.scopus.com/inward/record.url?eid=2-s2.0-85057986901&partnerID=MN8TOARS.
    10.2147/CEG.S166197
  41. Vieira da Silva, S.A.; Clemente, A.; Rocha, J.; Direito, R.; Marques, H.C.; Sepodes, B.; Figueira, M.-E.; Ribeiro, M.H.. "Anti-inflammatory effect of limonin from cyclodextrin (un)processed orange juices in in vivo acute inflammation and chronic rheumatoid arthritis models". Journal of Functional Foods 49 (2018): 146-153. http://www.scopus.com/inward/record.url?eid=2-s2.0-85051776212&partnerID=MN8TOARS.
    10.1016/j.jff.2018.08.024
  42. Sepodes, Bruno. "Thiadiazolidinone-8 Ameliorates Inflammation Associated with Experimental Colitis in Mice.". Pharmacology (2018): http://europepmc.org/abstract/med/28965119.
    10.1159/000471808
  43. Mateus, Vanessa; Rocha, João; Mota-Filipe, Helder; Sepodes, Bruno; Pinto, Rui. "Hemin reduces inflammation associated with TNBS-induced colitis". (2018): http://hdl.handle.net/10400.21/9220.
    10.2147/CEG.S166197
  44. Mateus, Vanessa; Rocha, João; Alves, Paula; Mota-Filipe, Hélder; Sepodes, Bruno; Pinto, Rui. "Thiadiazolidinone-8 ameliorates inflammation associated with experimental colitis in mice". (2018): http://hdl.handle.net/10400.21/7898.
    10.1159/000471808
  45. Mateus, Vanessa; Rocha, João; Alves, Paula; Mota-Filipe, Hélder; Sepodes, Bruno; Pinto, Rui. "Thiadiazolidinone-8 ameliorates inflammation associated with experimental colitis in mice". (2018): http://hdl.handle.net/10400.21/7898.
    10.1159/000471808
  46. Mateus, Vanessa; Rocha, João; Mota-Filipe, Helder; Sepodes, Bruno; Pinto, Rui. "Hemin reduces inflammation associated with TNBS-induced colitis". (2018): http://hdl.handle.net/10400.21/9220.
    10.2147/CEG.S166197
  47. Benedetta Polsinelli; Stelios Tsigkos; Frauke Naumann-Winter; Segundo Mariz; Bruno Sepodes. "Evolving prevalence of haematological malignancies in orphan designation procedures in the European Union". Orphanet Journal of Rare Diseases 12 1 (2017): https://doi.org/10.1186%2Fs13023-017-0567-7.
    10.1186/s13023-017-0567-7
  48. Sepodes, Bruno. "Demonstrating significant benefit of orphan medicines: analysis of 15 years of experience in Europe.". Drug discovery today (2017): http://europepmc.org/abstract/med/29024805.
    10.1016/j.drudis.2017.09.010
  49. Sepodes, Bruno. "Nonclinical data supporting orphan medicinal product designations: lessons from rare neurological conditions.". Drug discovery today (2017): http://europepmc.org/abstract/med/28987289.
    10.1016/j.drudis.2017.09.015
  50. Sepodes, Bruno. "Development of Exon Skipping Therapies for Duchenne Muscular Dystrophy: A Critical Review and a Perspective on the Outstanding Issues.". Nucleic acid therapeutics (2017): http://europepmc.org/abstract/med/28796573.
    10.1089/nat.2017.0682
  51. Sepodes, Bruno. "Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities.". The Journal of nutritional biochemistry (2017): http://europepmc.org/abstract/med/28494341.
    10.1016/j.jnutbio.2017.03.002
  52. Sepodes, Bruno. "Establishing rarity in the context of orphan medicinal product designation in the European Union.". Drug discovery today (2017): http://europepmc.org/abstract/med/28647377.
    10.1016/j.drudis.2017.06.003
  53. Sepodes, Bruno. "Regulatory and Scientific Advancements in Gene Therapy: State-of-the-Art of Clinical Applications and of the Supporting European Regulatory Framework.". Frontiers in medicine (2017): http://europepmc.org/abstract/med/29124055.
    10.3389/fmed.2017.00182
  54. Sepodes, Bruno. "Advanced Therapy Medicinal Products for Rare Diseases: State of Play of Incentives Supporting Development in Europe.". Frontiers in medicine (2017): http://europepmc.org/abstract/med/28560211.
    10.3389/fmed.2017.00053
  55. Mateus, Vanessa; Rocha, João; Alves, Paula; Mota-Filipe, Helder; Sepodes, Bruno; Pinto, Rui Manuel Amaro. "Anti-inflammatory effect of erythropoietin in the TNBS-induced colitis". (2017): http://hdl.handle.net/10400.21/6659.
    10.1111/bcpt.12663
  56. Mateus, Vanessa; Rocha, João; Alves, Paula; Mota-Filipe, Helder; Sepodes, Bruno; Pinto, Rui Manuel Amaro. "Anti-inflammatory effect of erythropoietin in the TNBS-induced colitis". (2017): http://hdl.handle.net/10400.21/6659.
    10.1111/bcpt.12663
  57. Sepodes B. "Regulation Of Orphan Medicinal Products In Europe: History Trends And Challenges.". (2016): http://europepmc.org/abstract/med/27673673.
    10.1016/j.clinthera.2016.07.101
  58. Figueira ME; Oliveira M; Direito R; Rocha J; Alves P; Serra AT; Duarte C; et al. "Protective effects of a blueberry extract in acute inflammation and collagen-induced arthritis in the rat.". (2016): http://europepmc.org/abstract/med/27551767.
    10.1016/j.biopha.2016.08.040
  59. Mateus V; Rocha J; Alves P; Mota-Filipe H; Sepodes B; Pinto RM. "Anti-Inflammatory Effect of Erythropoietin in the TNBS-induced Colitis.". (2016): http://europepmc.org/abstract/med/27579991.
    10.1111/bcpt.12663
  60. Sousa M; Machado V; Costa R; Figueira ME; Sepodes B; Barata P; Ribeiro L; Soares R. "Red Raspberry Phenols Inhibit Angiogenesis: A Morphological and Subcellular Analysis Upon Human Endothelial Cells.". (2016): http://europepmc.org/abstract/med/26590362.
    10.1002/jcb.25452
  61. Straub V; Balabanov P; Bushby K; Ensini M; Goemans N; De Luca A; Pereda A; et al. "Stakeholder cooperation to overcome challenges in orphan medicine development: the example of Duchenne muscular dystrophy.". (2016): http://europepmc.org/abstract/med/27302365.
    10.1016/s1474-4422(16)30035-7
  62. Mariz S; Reese JH; Westermark K; Greene L; Goto T; Hoshino T; Llinares-Garcia J; Sepodes B. "Worldwide collaboration for orphan drug designation.". (2016): http://europepmc.org/abstract/med/27245396.
    10.1038/nrd.2016.80
  63. Morel T; Lhoir A; Picavet E; Mariz S; Sepodes B; Llinares J; Cassiman D. "Regulatory watch: The orphan drug pipeline in Europe.". (2016): http://europepmc.org/abstract/med/27245390.
    10.1038/nrd.2016.96
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Capítulo de livro
  1. Câmara, Madalena Bettencourt da; Figueira, Maria Eduardo; Ferreira, João Pedro Borges; Coelho, Ana Varela; Feliciano, Rui; Silva, Andreia Bento da; Mecha, Elsa; et al. "Caracterização química e avaliação da actividade biológica da framboesa (Rubus Idaeus L.) : Contribuição para o desenvolvimento de uma alegação de saúde". 2019.
  2. Bettencourt-Câmara, Madalena; Sepodes, Bruno; Bronze, Rosário; Figueira, Maria-Eduardo. "Supplements in the EU: an updated analysis of health claims related to articular joint health". Book Publisher International, 2019.
  3. Câmara, Madalena Bettencourt da; Figueira, Maria Eduardo; Ferreira, João Pedro Borges; Coelho, Ana Varela; Feliciano, Rui; Silva, Andreia Bento da; Mecha, Elsa; et al. "Caracterização química e avaliação da actividade biológica da framboesa (Rubus Idaeus L.) : Contribuição para o desenvolvimento de uma alegação de saúde". 2019.
  4. Bettencourt-Câmara, Madalena; Sepodes, Bruno; Bronze, Rosário; Figueira, Maria-Eduardo. "Supplements in the EU: an updated analysis of health claims related to articular joint health". Book Publisher International, 2019.
Livro
  1. Sepodes, Bruno. Prontuário Terapêutico 11. 2012.
  2. Sepodes, Bruno. Prontuário Terapêutico 10. 2011.
  3. Sepodes, Bruno. Prontuário Terapêutico 9. 2010.
  4. Sepodes, Bruno. Prontuário Terapêutico 8. Portugal. 2009.
  5. Sepodes, Bruno. Prontuário Terapêutico 8. 2009.
Tese / Dissertação
  1. Carvalho, Marta Alexandra Bogalho Rodrigues de. "Advanced therapy medicinal products : new strategies for clinical applications of cell and gene therapy". Doutoramento, 2020. http://hdl.handle.net/10451/48501.
  2. Carvalho, Marta Alexandra Bogalho Rodrigues de. "Advanced therapy medicinal products : new strategies for clinical applications of cell and gene therapy". Doutoramento, 2020. http://hdl.handle.net/10451/48501.
  3. Soares, Leonor Mascarenhas Neto de Melo. "Nanjing Statements: A Formação e o Desenvolvimento de Competências do Farmacêutico para o Futuro da Profissão". Mestrado, 2019. http://hdl.handle.net/10451/43374.
  4. Carona, Mónica Tenreiro. "The effects of cage-divided housing on anxiety and working memory in mice". Mestrado, 2019. http://hdl.handle.net/10451/43344.
  5. Roma, João Gabriel Mira Calhau de Carvalho. "E-commerce no setor das farmácias: case-study de desenvolvimento em Portugal". Mestrado, 2019. http://hdl.handle.net/10451/43356.
  6. Carona, Mónica Tenreiro. "The effects of cage-divided housing on anxiety and working memory in mice". Mestrado, 2019. http://hdl.handle.net/10451/43344.
  7. Soares, Leonor Mascarenhas Neto de Melo. "Nanjing Statements: A Formação e o Desenvolvimento de Competências do Farmacêutico para o Futuro da Profissão". Mestrado, 2019. http://hdl.handle.net/10451/43374.
  8. Roma, João Gabriel Mira Calhau de Carvalho. "E-commerce no setor das farmácias: case-study de desenvolvimento em Portugal". Mestrado, 2019. http://hdl.handle.net/10451/43356.
  9. Ferreira, Pedro António Mendonça. "Ébola e Zika: lições e potenciais alterações decorrentes dos surtos". Mestrado, 2017. http://hdl.handle.net/10451/36079.
  10. Bacalhau, Patrícia Alexandra Santos. "O potencial colaborativo do farmacêutico comunitário na terapêutica do cancro da próstata". Mestrado, 2017. http://hdl.handle.net/10451/36000.
  11. Bugalho, Ana Rita Flores. "Doenças transmissíveis, doenças não transmissíveis e os desafios do século XXI". Mestrado, 2017. http://hdl.handle.net/10451/35944.
  12. Ferreira, Pedro António Mendonça. "Ébola e Zika: lições e potenciais alterações decorrentes dos surtos". Mestrado, 2017. http://hdl.handle.net/10451/36079.
  13. Bacalhau, Patrícia Alexandra Santos. "O potencial colaborativo do farmacêutico comunitário na terapêutica do cancro da próstata". Mestrado, 2017. http://hdl.handle.net/10451/36000.
  14. Bugalho, Ana Rita Flores. "Doenças transmissíveis, doenças não transmissíveis e os desafios do século XXI". Mestrado, 2017. http://hdl.handle.net/10451/35944.
  15. Mateus, Vanessa. "Pharmacological modulation of inflammation associated with inflammatory bowel disease : - study in an animal model". Doutoramento, 2016. http://hdl.handle.net/10451/24862.
  16. Saramago, Tiago Daniel Cordeiro. "A consulta do viajante em farmácia : papel do farmacêutico no aconselhamento e terapêutica do viajante". Mestrado, 2016. http://hdl.handle.net/10451/34509.
  17. Antunes, Joana Filipa Mendes. "Construction of glucocorticoid receptor minigene to study alternative splicing mechanism : the role of dehydroepiandrosterone on the receptor for activated C kinase-1 expression". Mestrado, 2016. http://hdl.handle.net/10451/34591.
  18. Fonseca, Maria Sofia Soares. "Construção de uma base de dados de estudos clínicos sobre factores de transferência". Mestrado, 2016. http://hdl.handle.net/10451/27598.
  19. Helfrich, Alexandra Sofia Pontes Leite. "Reprogramming Fear Memory through the Inhibition of GSK-3 during Reconsolidation". Mestrado, 2016. http://hdl.handle.net/10451/35771.
  20. Oliveira, Cláudia Sofia Ferraz. "Abordagem Farmacoterapêutica da fibrose quística". Mestrado, 2015. http://hdl.handle.net/10451/26867.
  21. Moreira, Alexandra Isabel da Costa. "A qualidade do medicamento : contributos para uma abordagem diferencial entre o medicamento humano e o medicamento veterinário". Mestrado, 2015. http://hdl.handle.net/10451/27046.
  22. Guerra, Joana Filipa Salgueiro. "Potencialidades da manipulação farmacológica de órgãos sólidos para transplante". Mestrado, 2015. http://hdl.handle.net/10451/26828.
  23. Costa, Manuel Dias. "Perspectivas terapêuticas na abordagem da esquizofrenia". Mestrado, 2015. http://hdl.handle.net/10451/26794.
  24. Reis, Inês Antunes dos. "Farmacoterapia da Depressão na Criança e no Adolescente". Mestrado, 2015. http://hdl.handle.net/10451/26883.
  25. Trigo, Daniel Artur Pereira da Mota dos Santos. "A utilização de medicamentos biológicos na terapêutica da asma". Mestrado, 2015. http://hdl.handle.net/10451/46019.
  26. Ferra, Ana Maria Monteiro. "Abordagem farmacoterapêutica da fibrose quística". Mestrado, 2014. http://hdl.handle.net/10451/26808.
  27. Espadanal, Daniela. "Farmacoterapia da depressão em crianças e adolescentes". Mestrado, 2014. http://hdl.handle.net/10451/25724.
  28. Ferraz, Vanessa Alexandra Duarte. "Abordagem farmacoterapêutica da fibrose quística". Mestrado, 2014. http://hdl.handle.net/10451/26809.
  29. Cláudio, Tiago José Gomes. "Farmacoterapia da depressão em doentes com Síndrome da Imunodeficiência Adquirida". Mestrado, 2014. http://hdl.handle.net/10451/26784.
  30. Ambaram, Miguel Bhatt. "Terapêutica da diabetes mellitus do tipo 2". Mestrado, 2014. http://hdl.handle.net/10451/26748.
  31. Loureiro, Joana Rebelo Mendes. "Abordagem farmacoterapêutica na fibrose quística". Mestrado, 2014. http://hdl.handle.net/10451/26842.
  32. Amaral, Sara Vieira. "Abordagem farmacoterapêutica da fibrose quística". Mestrado, 2014. http://hdl.handle.net/10451/26747.
  33. Lopes, Ana Raquel Gaspar Gomes Cardoso. "Perspectivas terapêuticas na abordagem da esquizofrenia". Mestrado, 2014. http://hdl.handle.net/10451/26838.
  34. Pinheiro, Ana Catarina Santos. "Perspectivas terapêuticas na abordagem da esquizofrenia". Mestrado, 2014. http://hdl.handle.net/10451/26877.
  35. Páscoa, Dídia Helena Teixeira da Silva. "Abordagem farmacoterapêutica da fibrose quística". Mestrado, 2014. http://hdl.handle.net/10451/26871.
  36. Mendes, Ana Catarina Simões Martins. "Perspectivas terapêuticas na abordagem da esquizofrenia". Mestrado, 2014. http://hdl.handle.net/10451/26853.
  37. Raposo, Carla Sofia Alexandre. "O papel das normas de orientação clínica no uso racional do medicamento em oncologia". Mestrado, 2014. http://hdl.handle.net/10451/15860.
  38. Silva, Fábio da Costa. "Orphan medicines and therapeutic innovation". Mestrado, 2014. http://hdl.handle.net/10451/26906.
  39. Santos, Sara Manuela Barreiros dos. "Imunoterapia oncológica: avanços terapêuticos, riscos e benefícios". Mestrado, 2013. http://hdl.handle.net/10451/24607.
  40. Santos, Sara Manuela Barreiros dos. "Imunoterapia oncológica: avanços terapêuticos, riscos e benefícios". Mestrado, 2013. http://hdl.handle.net/10451/24836.
  41. Cândido, Sara Filipa Fernandes. "Fisiopatologia e terapêutica da dor neuropática". Mestrado, 2013. http://hdl.handle.net/10451/46030.
  42. Repolho, Marta Batista da Rosa. "Imunoterapia na artrite reumatóide em Portugal : avanços terapêuticos, riscos e benefícios". Mestrado, 2013. http://hdl.handle.net/10451/15295.
  43. Russo, Joana Isabel Silveira. "Nefrotoxicidade induzida por fármacos: caracterização da realidade hospitalar, medidas preventivas e oportunidades de intervenção". Mestrado, 2013. http://hdl.handle.net/10451/11257.
  44. Raposo, João Paulo Freire de Carvalho e Castro. "Abordagem farmacoterapêutica das doenças inflamatórias do intestino". Mestrado, 2013. http://hdl.handle.net/10451/46025.
  45. Rocha, João Pedro Fidalgo, 1982-. "Inflamação e mecanismos citoprotectores em modelos de lesão pulmonar". Doutoramento, 2013. http://hdl.handle.net/10451/9267.
  46. Salgueiro, Catarina Vicente Barroso Reis. "Efeito terapêutico de agonistas dos receptores canabinóides". Mestrado, 2013. http://hdl.handle.net/10451/46185.
  47. Nogueira , João André Jorge. "A utilização de anticorpos na terapêutica antitumoral". Mestrado, 2013. http://hdl.handle.net/10451/30599.
  48. Requetim, Luís Ricardo Charneca. "A utilização em terapêutica de substâncias com atividade nootrópica". Mestrado, 2013. http://hdl.handle.net/10400.1/6885.
  49. Amorim, Daniela Sofia Rodrigues. "A terapêutica da dor neuropática em Portugal: proposta de uma linha orientadora de uniformização". Mestrado, 2012. http://hdl.handle.net/10451/11309.
  50. Apolinário, Célia Luísa dos Santos. "Farmacoterapia no cancro da mama". Mestrado, 2012. http://hdl.handle.net/10400.1/3521.
  51. Henriques, Sónia Isabel Gonçalves. "Implementação de um painel de provadores de alimentos. Comparação dos hábitos de consumo alimentar e acuidade sensorial de dois grupos de indivíduos". Mestrado, 2012. http://hdl.handle.net/10451/11355.
  52. Damásio, Mariana Peig Dória. "Farmacoterapia das perturbações do sono: insónia". Mestrado, 2011. http://hdl.handle.net/10400.1/2724.
  53. Costa, Cátia Sofia Piriquito. "Contraceptivos orais". Mestrado, 2011. http://hdl.handle.net/10400.1/1757.
  54. Freitas, Cassius Francisco de Andrade. "Avaliação da atividade anti-inflamatória de um extrato de framboesa na Artrite Reumatóide". Mestrado, 2011. http://hdl.handle.net/10451/11010.
  55. Santos, Inês Isabel Carromeu. "Terapêutica hormonal de substituição". Mestrado, 2010. http://hdl.handle.net/10400.1/12187.
  56. Sepodes, Bruno Miguel Nogueira, 1977-. "Modulação farmacológica da lesão induzida por isquémia- reperfusão hepática". Doutoramento, 2008. http://sibul.reitoria.ul.pt/F/?func=item-global&doc_library=ULB01&type=03&doc_number=000533091.
Distinções

Outra distinção

2012 Nutrition Awards 2012 – 1a Menção Honrosa
Fundação Calouste Gulbenkian, Portugal
2010 Arthur E. Baue Award
2009 2nd Poster Prize at the 21st DIA Annual Euromeeting 2009
2007 Menção honrosa do prémio das comunicações livres
Sociedade Portuguesa de Cirurgia, Portugal
2007 Prémio Ana Maria Correia
2006 Prémio da Melhor Comunicação Livre
2005 1º Prémio das Comunicações Livres (Investigação Experimental)
2002 Young Scientist Award
1998 Prémio Natiris de Fitoterapia