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Tânia Cova completed the degree in Industrial Chemistry from the University of Coimbra in 2009, obtained her MSc degree in Chemistry in 2011, specialized in Quality Control and Environment. In 2018, she obtained a Doctorate degree in Chemistry at the same University, specialized in Macromolecular Chemistry, with several contributions in the areas of supramolecular and computational chemistry, and data science. She was awarded a Junior Researcher contract under the 2nd edition of the Individual Call to Scientific Employment Stimulus 2018 assigned by FCT, and started working at CCC/UC in July 2020. She was also awarded a Ph.D. Transition Fellowship (10000 eur) assigned by EIT Health in 2018 intended to support the exploitation of an innovative idea related to the design and production of a targeted transdermal device integrating multifunctional nanocarriers for treating advanced melanoma. She brings together vast experience in computational modeling and simulation applied to pharmaceutical formulation design, and optimization, standing out in the areas of nanotechnology. She is a team member of the NanoLIP- 01/SAICT/2021 project, which aims to provide a more robust proof of concept for the antitumor efficacy data associated with the development of nanomedicines for the treatment of glioblastoma and to promote the transition (TRL3 to TRL6) to a manufacturing process for ultra-small nanostructured lipid carriers that will enable translation to industrial scale. She has performed computational studies of polyelectrolyte arrangements, including DNA-origami type and aptamer-containing chains, and also aptamer- and peptide-carbohydrate conjugates as a new strategy to Improve pollutant and drug recognition, and tumor targeting. The main contributions are included in 9 book chapters, 38 scientific articles (h-index 19), 1 international patent (WO/2021/111364A1), 1 book edition, 1 manual, 4 special issue editions as Guest Editor, 31 oral communications in scientific conferences, 21 conference posters, 6 event organizations, and other ad hoc missions for knowledge transfer directed to undergraduate students. She has received 6 awards and/or honors. She lectured courses in General Chemstry, Chemometrics and Pattern Recognition and Statistical and Multivariate Analysis in R (with 14 completed editions since 2015), at the University of Coimbra, and (co)supervised several MSc and BSc theses. She has also been involved as a jury member, in the organization of international meetings, and in several outreach activities for knowledge transfer directed to undergraduate students. She has developed modeling approaches for understanding the factors that govern the formation of supramolecular nanostructures for drug delivery and water remediation, resorting to atomistic simulations, free-energy calculations and machine learning. The main topics gathered different aspects in quantifying host-guest binding, but her research interests include also the design of coarse-grained models for polyelectrolyte systems and polymer networks for drug delivery and contaminant removal in environmental matrices, and timely topics of machine learning and data science addressing multivariate bio/chemical data. She was a research fellow of ERA-NET ProWsper-WaterJPI/006/2016, in which she implemented data science tools for rationalizing and predicting physical-chemical properties and thermodynamic signatures from simulation results of systems directed at removing phytopharmaceutical compounds from water. She was nominated MC member of COST Action CA19145 - (SensorFINT - European Network to ensure food integrity using non-destructive spectral sensors) involving 27 countries. She is an expert evaluator for the European Commission Horizon Europe programme.
Identificação

Identificação pessoal

Nome completo
Tânia Firmino Guerra Guerreiro Cova

Nomes de citação

  • Cova, Tânia Firmino Guerra Guerreiro da

Identificadores de autor

Ciência ID
D118-F731-FAFF
ORCID iD
0000-0002-2840-6091

Endereços de correio eletrónico

  • tfirmino.gc@gmail.com (Profissional)
  • tfirmino@qui.uc.pt (Profissional)

Websites

Domínios de atuação

  • Ciências Exatas - Química

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador proficiente (C1) Utilizador elementar (A1) Utilizador proficiente (C1)
Francês Utilizador elementar (A1) Utilizador proficiente (C1) Utilizador elementar (A1) Utilizador proficiente (C1)
Formação
Grau Classificação
2014/12/01 - 2018/11/30
Concluído
Chemistry (Doutoramento)
Especialização em Macromolecular Chemistry
University of Coimbra, Portugal
"Simulation of Supramolecular Systems for Drug Delivery Based on Inclusion complexes (available from: https://www.dropbox.com/s/roz9r145978178h/Thesis_PhD_TaniaCova.zip?dl=0)" (TESE/DISSERTAÇÃO)
Unanimously approved with Distinction and Praise
2009 - 2011/07/19
Concluído
Chemistry (Mestrado integrado)
Especialização em Quality Control and Environment
University of Coimbra, Portugal
"Aplicações em quimiometria. Do diagnóstico médico à cientometria" (TESE/DISSERTAÇÃO)
18
2006 - 2009
Concluído
Industrial Chemistry (Licenciatura)
University of Coimbra, Portugal
"Síntese e Esterificação de carboxifenilporfirinas assistida por microondas" (TESE/DISSERTAÇÃO)
-
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2020/07/01 - Atual Investigador Contratado (Investigação) Universidade de Coimbra, Portugal
Universidade de Coimbra, Portugal
2019/07/01 - 2020/06/30 Pós-doutorado (Investigação) Coimbra Chemistry Centre, University of Coimbra, Portugal
Universidade de Coimbra, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2018/12/10 - 2019/04/09 Research Fellow ERA-NET ProWsper-WaterJPI/006/2016 - How to protect water, soil and plants production all together Coimbra Chemistry Centre, University of Coimbra, Portugal
2014/09/01 - 2018/11/30 PhD Student, FCT Grant SFRH/BD/95459/2013 University of Coimbra, Portugal
2015/01/01 - 2018/06/06 Member of the teaching team of the E-learning course on "Statistical and multivariate analysis in R" University of Coimbra, Portugal
2014/08/01 - 2014/11/30 Research Fellow - Incentivo/QUI/UI0313/2014 - Pattern recognition in Chemistry: from multicomponent systems to the scientific production in the CCC and other institutions Coimbra Chemistry Centre, University of Coimbra, Portugal
2013/11/01 - 2014/07/31 Data Analyst of multicomponent systems. Coimbra Chemistry Centre, University of Coimbra, Portugal
2013/07/01 - 2013/10/31 Research Fellow at CQC Coimbra Chemistry Centre, University of Coimbra, Portugal
2013/04/01 - 2013/06/30 Data Analyst of multicomponent systems Coimbra Chemistry Centre, University of Coimbra, Portugal
2012/07/01 - 2013/03/31 Research Fellow PTDC/QUIQUI/101442/2008 Coimbra Chemistry Centre, University of Coimbra, Portugal
2011/07/20 - 2012/06/30 Data Analyst of multicomponent systems Coimbra Chemistry Centre, University of Coimbra, Portugal
2009/09/01 - 2009/12/31 Research Trainee Analytical Chemistry/Microbiology University of Coimbra, Portugal
Projetos

Bolsa

Designação Financiadores
2024/01/01 - Atual 3BBBioprinting - Provasde Conceito UC by Santander Universidades - WO2021111364 - NANOSTRUCTURED DRUG DELIVERY SYSTEM AS A MULTIFUNCTIONAL PLATFORM FOR THERAPY
3BBBioprinting
Investigador
Coimbra Chemistry Centre, Faculty of Sciences and Technology, University of Coimbra, Portugal
Em curso
2022 - Atual NanoLIP- 01/SAICT/2021 - SAICT (Proof-of-Concepts Projects) Project: 181224 : UNIVERSIDADE DE COIMBRA
01/SAICT/2021 - 181224
Investigador
Coimbra Chemistry Centre, University of Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2021/01/01 - Atual European Network for assuring food integrity using non-destructive spectral sensors
CA19145
Investigador
Coimbra Chemistry Centre, Faculty of Sciences and Technology, University of Coimbra, Portugal
COST Association
Em curso
2023/05/01 - 2023/12/31 Carbohydrate-templated structures for detection and removal of water pollutants
2022.57089.CPCA.A0
Investigador responsável
Coimbra Chemistry Centre, Faculty of Sciences and Technology, University of Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2023/05/01 - 2023/12/31 Characterization of antibacterial molecules through electronic structure calculations and computational learning methods
022.56990.CPCA.A0
Co-Investigador Responsável (Co-IR)
Coimbra Chemistry Centre, Faculty of Sciences and Technology, University of Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2016 - 2019 Dual nanostructured lipid carriers as a multifunctional platform for brain tumor therapy
POCI-01-0145-FEDER-016648
Investigador
Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2014/12/01 - 2018/11/30 Simulation of Supramolecular Systems for Drug Delivery Based on Inclusion Complexes
SFRH/BD/95459/2013
Bolseiro de Doutoramento
Universidade de Coimbra Centro de Química de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2023 - Atual ReMade@ARI - REcyclable MAterials DEvelopment at Analytical Reserach Infrastructures
101058414
Investigador
Coimbra Chemistry Centre, University of Coimbra, Portugal
Em curso
2023/03/12 - 2026/03/11 Interação calcitonina-receptor promovida por nanopartículas guiadas por péptidos como uma nova abordagem para tratamento de glioblastoma
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2021/01/01 - 2025/12/31 Instituto de Ciências Moleculares
LA/P/0056/2020
Universidade de Coimbra Centro de Química de Coimbra, Portugal

Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Centro de Investigação em Química, Portugal

FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal

Universidade de Coimbra, Portugal

Universidade de Lisboa Faculdade de Ciências, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Centro de Química Estrutural, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2019/01/01 - 2019/12/31 Centro de Química - Coimbra
UID/QUI/00313/2019
Universidade de Coimbra, Portugal

Universidade de Coimbra Centro de Química de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2016/07/01 - 2019/06/30 Co-encapsulação em transportadores lipídicos nanoestruturados como uma plataforma multifuncional para o tratamento de tumores cerebrais
PTDC/CTM-NAN/2658/2014
Universidade de Lisboa Faculdade de Farmácia, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. Lã, Filipa M.B.; Polo, Nuria; Granqvist, Svante; Cova, Tânia; Pais, Alberto C.. "Female Voice-Related Sexual Attractiveness to Males: Does it Vary With Different Degrees of Conception Likelihood?". Journal of Voice 37 3 (2023): 467.e19-467.e31. http://dx.doi.org/10.1016/j.jvoice.2021.02.006.
    Publicado
  2. Utzeri, Gianluca; Cova, Tânia F.; Murtinho, Dina; Pais, Alberto A.C.C.; Valente, Artur J.M.. "Insights on macro- and microscopic interactions between Confidor and cyclodextrin-based nanosponges". Chemical Engineering Journal 455 (2023): 140882. http://dx.doi.org/10.1016/j.cej.2022.140882.
    Publicado • 10.1016/j.cej.2022.140882
  3. Basso, João; Mendes, Maria; Cova, Tânia; Sousa, João; Pais, Alberto; Fortuna, Ana; Vitorino, Rui; Vitorino, Carla. "A Stepwise Framework for the Systematic Development of Lipid Nanoparticles". Biomolecules 12 2 (2022): 223. http://dx.doi.org/10.3390/biom12020223.
    10.3390/biom12020223
  4. Cova, Tânia F.; Murtinho, Dina; Aguado, Roberto; Pais, Alberto A. C. C.; Valente, Artur J. M.. "Cyclodextrin Polymers and Cyclodextrin-Containing Polysaccharides for Water Remediation". Polysaccharides 2 1 (2021): 16-38. http://dx.doi.org/10.3390/polysaccharides2010002.
    Acesso aberto • 10.3390/polysaccharides2010002
  5. Basso, João; Mendes, Maria; Silva, Jessica; Cova, Tânia; Luque-Michel, Edurne; Jorge, Andreia F.; Grijalvo, Santiago; et al. "Sorting hidden patterns in nanoparticle performance for glioblastoma using machine learning algorithms". International Journal of Pharmaceutics 592 (2021): 120095. http://dx.doi.org/10.1016/j.ijpharm.2020.120095.
    Publicado • 10.1016/j.ijpharm.2020.120095
  6. Miranda, Margarida; Cova, Tânia; Augusto, Cátia; Pais, Alberto A. C. C.; Cardoso, Catarina; Vitorino, Carla. "Diving into Batch-to-Batch Variability of Topical Products-a Regulatory Bottleneck". Pharmaceutical Research 37 11 (2020): http://dx.doi.org/10.1007/s11095-020-02911-y.
    Publicado • 10.1007/s11095-020-02911-y
  7. Basso, João; Mendes, Maria; Silva, Jessica; Sereno, José; Cova, Tânia; Oliveira, Rui; Fortuna, Ana; et al. "Peptide-lipid nanoconstructs act site-specifically towards glioblastoma growth impairment". European Journal of Pharmaceutics and Biopharmaceutics (2020): http://dx.doi.org/10.1016/j.ejpb.2020.08.015.
    No prelo • 10.1016/j.ejpb.2020.08.015
  8. Mendes, Maria; Basso, João; Silva, Jessica; Cova, Tânia; Sousa, João; Pais, Alberto; Vitorino, Carla. "Biomimeting ultra-small lipid nanoconstructs for glioblastoma treatment: a computationally guided experimental approach". International Journal of Pharmaceutics (2020): 119661. http://dx.doi.org/10.1016/j.ijpharm.2020.119661.
    No prelo • 10.1016/j.ijpharm.2020.119661
  9. Mendes, Maria; Cova, Tânia; Basso, João; Ramos, M. Luísa; Vitorino, Rui; Sousa, João; Pais, Alberto; Vitorino, Carla. "Hierarchical design of hyaluronic acid-peptide constructs for glioblastoma targeting: Combining insights from NMR and molecular dynamics simulations". Journal of Molecular Liquids (2020): 113774. http://dx.doi.org/10.1016/j.molliq.2020.113774.
    10.1016/j.molliq.2020.113774
  10. Cova, Tânia Firmino Guerra Guerreiro da. "Deep Learning for Deep Chemistry: Optimizing the Prediction of Chemical Patterns". Frontiers in Chemistry (2019): http://dx.doi.org/10.3389/fchem.2019.00809.
    10.3389/fchem.2019.00809
  11. Anna Aviñó; Andreia F. Jorge; César S. Huertas; Tânia F.G.G. Cova; Alberto Pais; Laura M. Lechuga; Ramon Eritja; Carme Fabrega. "Aptamer-peptide conjugates as a new strategy to modulate human a-thrombin binding affinity". Biochimica et Biophysica Acta (BBA) - General Subjects 1863 10 (2019): 1619-1630. https://doi.org/10.1016%2Fj.bbagen.2019.06.014.
    Publicado • 10.1016/j.bbagen.2019.06.014
  12. Cova, Tânia Firmino Guerra Guerreiro da. "Computational Approaches in Theranostics: Mining and Predicting Cancer Data". Pharmaceutics (2019): https://www.mdpi.com/1999-4923/11/3/119.
    Acesso aberto • Publicado • 10.3390/pharmaceutics11030119
  13. Cova, Tânia F.; Milne, Bruce F.; Pais, Alberto A. C. C.. "Host flexibility and space filling in supramolecular complexation of cyclodextrins: A free-energy-oriented approach". Carbohydrate Polymers 205 1 (2019): 42-54. https://www.sciencedirect.com/science/article/pii/S0144861718311858.
    Publicado • 10.1016/j.carbpol.2018.10.009
  14. Cova, Tânia F.G.G.; Murtinho, Dina; Pais, Alberto A.C.C.; Valente, Artur J.M.. "Cyclodextrin-based Materials for Removing Micropollutants From Wastewater". Current Organic Chemistry 22 22 (2018): 2150-2181. http://dx.doi.org/10.2174/1385272822666181019125315.
    Publicado • 10.2174/1385272822666181019125315
  15. Basso, João; Mendes, Maria; Cova, Tânia F. G. G.; Sousa, João J.; Pais, Alberto A. C. C.; Vitorino, Carla. "Analytical Quality by Design (AQbD) as a multiaddressable platform for co-encapsulating drug assays". Analytical Methods 10 47 (2018): 5659-5671. http://dx.doi.org/10.1039/c8ay01695j.
    Publicado • 10.1039/c8ay01695j
  16. Basso, João; Miranda, Ana; Nunes, Sandra; Cova, Tânia; Sousa, João; Vitorino, Carla; Pais, Alberto. "Hydrogel-Based Drug Delivery Nanosystems for the Treatment of Brain Tumors". Gels 4 3 (2018): 62. http://dx.doi.org/10.3390/gels4030062.
    Acesso aberto • Publicado • 10.3390/gels4030062
  17. Nunes, Sandra C.C.; Cova, Tânia F. G. G.; Dias, RIta S.; Pais, Alberto A. C. C.. "Adsorption of charged macromolecules upon multicomponent responsive surfaces, 2018 PCCP HOT Article". Physical Chemistry Chemical Physics 20 30 (2018): 19811-19818. https://pubs.rsc.org/en/content/articlelanding/2018/cp/c8cp03383h#!divAbstract.
    Publicado • 10.1039/C8CP03383H
  18. Cova, Tânia F.; Murtinho, Dina; Pais, Alberto A. C. C.; Valente, Artur J. M.. "Combining Cellulose and Cyclodextrins: Fascinating Designs for Materials and Pharmaceutics". Frontiers in Chemistry 6 271 (2018): 1-19. http://dx.doi.org/10.3389/fchem.2018.00271.
    Acesso aberto • Publicado • 10.3389/fchem.2018.00271
  19. Silva, Jessica; Mendes, Maria; Cova, Tânia; Sousa, João; Pais, Alberto; Vitorino, Carla. "Unstructured Formulation Data Analysis for the Optimization of Lipid Nanoparticle Drug Delivery Vehicles". AAPS PharmSciTech 19 5 (2018): 2383-2394. http://dx.doi.org/10.1208/s12249-018-1078-0.
    Publicado • 10.1208/s12249-018-1078-0
  20. Mendes, Maria; Miranda, Ana; Cova, Tânia; Gonçalves, Lídia; Almeida, António J.; Sousa, João J.; do Vale, Maria L.C.; et al. "Modeling of ultra-small lipid nanoparticle surface charge for targeting glioblastoma". European Journal of Pharmaceutical Sciences 117 1 (2018): 255-269. https://www.sciencedirect.com/science/article/pii/S0928098718301015?via%3Dihub.
    Publicado • 10.1016/j.ejps.2018.02.024
  21. Cova, Tânia F. G. G.; Milne, Bruce F.; Nunes, Sandra C. C.; Pais, Alberto A. C. C.. "Drastic Stabilization of Junction Nodes in Supramolecular Structures Based on Host–Guest Complexes". Macromolecules 51 7 (2018): 2732-2741. http://dx.doi.org/10.1021/acs.macromol.8b00154.
    Publicado • 10.1021/acs.macromol.8b00154
  22. Encarnação, Telma; Arranja, Cláudia T.; Cova, Tânia F. G. G.; Pais, Alberto A. C. C.; Campos, Maria G.; Sobral, Abílio J. F. N.; Burrows, Hugh D.. "Monitoring oil production for biobased feedstock in the microalga Nannochloropsis sp.: a novel method combining the BODIPY BD-C12 fluorescent probe and simple image processing". Journal of Applied Phycology 30 4 (2018): 2273-2285. http://dx.doi.org/10.1007/s10811-018-1437-y.
    Publicado • 10.1007/s10811-018-1437-y
  23. Alagia, Adele; Jorge, Andreia F.; Aviñó, Anna; Cova, Tânia F. G. G.; Crehuet, Ramon; Grijalvo, Santiago; Pais, Alberto A. C. C.; Eritja, Ramon. "Exploring PAZ/3'-overhang interaction to improve siRNA specificity. A combined experimental and modeling study". Chemical Science 9 8 (2018): 2074-2086. http://dx.doi.org/10.1039/c8sc00010g.
    Acesso aberto • Publicado • 10.1039/c8sc00010g
  24. Miranda, Ana; Cova, Tânia; Sousa, João; Vitorino, Carla; Pais, Alberto. "Computational modeling in glioblastoma: from the prediction of blood–brain barrier permeability to the simulation of tumor behavior". Future Medicinal Chemistry 10 1 (2018): 121-131. http://dx.doi.org/10.4155/fmc-2017-0128.
    Publicado • 10.4155/fmc-2017-0128
  25. Cova, Tânia F.G.G.; Jarmelo, Susana; Nunes, Sandra C.C.; Formosinho, Sebastião J.; de Melo, J. Sérgio Seixas; Pais, Alberto. "Seeing is believing: A graphical reference framework for multi-criteria evaluation". Evaluation 23 4 (2017): 479-494. http://dx.doi.org/10.1177/1356389017733336.
    Publicado • 10.1177/1356389017733336
  26. Cova, Tânia F. G. G.; Pais, Alberto A. C. C.; Seixas de Melo, J. Sérgio. "Reconstructing the historical synthesis of mauveine from Perkin and Caro: procedure and details". Scientific Reports 7 1 (2017): http://dx.doi.org/10.1038/s41598-017-07239-z.
    Publicado • 10.1038/s41598-017-07239-z
  27. Cova, Tânia F.G.G.; Nunes, Sandra C.C.; Valente, Artur J.M.; Pinho e Melo, Teresa M.V.D.; Pais, Alberto A.C.C.. "Properties and patterns in anion-receptors: A closer look at bambusurils". Journal of Molecular Liquids 242 (2017): 640-652. http://dx.doi.org/10.1016/j.molliq.2017.07.065.
    Publicado • 10.1016/j.molliq.2017.07.065
  28. Cova, Tânia F.G.G.; Nunes, Sandra C.C.; Pinho e Melo, Teresa M.V.D.; Pais, Alberto A.C.C.. "Bambusurils as effective ion caging agents: Does desolvation guide conformation?". Chemical Physics Letters 672 (2017): 89-96. http://dx.doi.org/10.1016/j.cplett.2017.01.029.
    Publicado • 10.1016/j.cplett.2017.01.029
  29. Cova, Tânia F. G. G.; Nunes, Sandra C. C.; Pais, Alberto A. C. C.. "Free-energy patterns in inclusion complexes: the relevance of non-included moieties in the stability constants". Physical Chemistry Chemical Physics 19 7 (2017): 5209-5221. http://pubs.rsc.org/en/Content/ArticleLanding/2017/CP/C6CP08081B#!divAbstract.
    Publicado • 10.1039/c6cp08081b
  30. Jorge, Andreia F.; Nunes, Sandra C.C.; Cova, Tânia F.G.G.; Pais, Alberto A.C.C.. "Cooperative action in DNA condensation". Current Opinion in Colloid & Interface Science 26 (2016): 66-74. http://dx.doi.org/10.1016/j.cocis.2016.09.014.
    Publicado • 10.1016/j.cocis.2016.09.014
  31. de Castro, Catherine S.; Cova, Tânia F.G.G.; Pais, Alberto C.C.; Pinheiro, Daniela; Nuñez, Cristina; Lodeiro, Carlos; Seixas de Melo, J. Sérgio. "Probing metal cations with two new Schiff base bischromophoric pyrene based chemosensors: Synthesis, photophysics and interactions patterns". Dyes and Pigments 134 (2016): 601-612. http://dx.doi.org/10.1016/j.dyepig.2016.08.016.
    Publicado • 10.1016/j.dyepig.2016.08.016
  32. Teixeira, Raquel S.; Cova, Tânia F.G.G.; Silva, Sérgio M.C.; Oliveira, Rita; do Vale, M. Luísa C.; Marques, Eduardo F.; Pais, Alberto A.C.C.; Veiga, Francisco J.B.. "Novel serine-based gemini surfactants as chemical permeation enhancers of local anesthetics: A comprehensive study on structure–activity relationships, molecular dynamics and dermal delivery". European Journal of Pharmaceutics and Biopharmaceutics 93 (2015): 205-213. http://dx.doi.org/10.1016/j.ejpb.2015.02.024.
    Publicado • 10.1016/j.ejpb.2015.02.024
  33. Cova, Tânia F.G.G.; Jarmelo, Susana; Formosinho, Sebastião J.; de Melo, J. Sérgio Seixas; Pais, Alberto A.C.C.. "Unsupervised characterization of research institutions with task-force estimation". Journal of Informetrics 9 1 (2014): 59-68. http://dx.doi.org/10.1016/j.joi.2014.11.005.
    Publicado • 10.1016/j.joi.2014.11.005
  34. Teixeira, Raquel S.; Cova, Tânia F.G.G.; Silva, Sérgio M.C.; Oliveira, Rita; Araújo, Maria J.; Marques, Eduardo F.; Pais, Alberto A.C.C.; Veiga, Francisco J.B.. "Lysine-based surfactants as chemical permeation enhancers for dermal delivery of local anesthetics". International Journal of Pharmaceutics 474 1-2 (2014): 212-222. http://dx.doi.org/10.1016/j.ijpharm.2014.08.002.
    Publicado • 10.1016/j.ijpharm.2014.08.002
  35. Lopes, Ana C.; Cova, Tânia F.G.G.; Pais, Alberto A.C.C.; Pereira, Jorge L.G.F.S.C.; Colaço, Bruno; Cabrita, António M.S.. "Improving discrimination in the grading of rat mammary tumors using two-dimensional mapping of histopathological observations". Experimental and Toxicologic Pathology 66 1 (2013): 73-80. http://dx.doi.org/10.1016/j.etp.2013.09.001.
    Publicado • 10.1016/j.etp.2013.09.001
  36. Nunes, Sandra C. C.; Cova, Tânia F. G. G.; Pais, A. A. C. C.. "A new perspective on correlated polyelectrolyte adsorption: Positioning, conformation, and patterns". The Journal of Chemical Physics 139 5 (2013): 054906. http://dx.doi.org/10.1063/1.4817338.
    Publicado • 10.1063/1.4817338
  37. Cova, Tânia F.G.G.; Pereira, Jorge L.G.F.S.C.; Pais, Alberto A.C.C.. "Is standard multivariate analysis sufficient in clinical and epidemiological studies?". Journal of Biomedical Informatics 46 1 (2012): 75-86. http://dx.doi.org/10.1016/j.jbi.2012.09.005.
    Publicado • 10.1016/j.jbi.2012.09.005
  38. Cova, Tânia F. G. G.; Pais, Alberto A. C. C.; Formosinho, Sebastião J.. "Iberian universities: a characterisation from ESI rankings". Scientometrics 94 3 (2012): 1239-1251. http://dx.doi.org/10.1007/s11192-012-0792-8.
    Publicado • 10.1007/s11192-012-0792-8
Capítulo de livro
  1. Cova, Tânia; Nunes, Sandra; Vitorino, Carla; Ferreira, Márcio; Rondon-Villarreal, Paola; Pais, Alberto. "In silico approaches for polymeric nanocomposites". In In-Silico Approaches to Macromolecular Chemistry, 503-531. Elsevier, 2023.
    Publicado • 10.1016/b978-0-323-90995-2.00010-2
  2. Cova, Tânia F.G.G.; Nunes, Sandra C.C.; Pais, Alberto A.C.C.. "Artificial intelligence to speed up active compounds screening". In New Insights Into Glioblastoma, 271-284. Elsevier, 2023.
    Publicado • 10.1016/b978-0-323-99873-4.00002-5
  3. Cova, Tânia Firmino Guerra Guerreiro da. "Artificial Intelligence and Quantum Computing as the Next Pharma Disruptors". In Artificial Intelligence in Drug Design, editado por Alexander Heifetz. Springer Natura, 2021.
    Publicado
  4. "Cyclodextrin-Based Polymers for Pollutant Removal". In Applications of Biodegradable and Bio-Based Polymers for Human Health and a Cleaner Environment. Taylor & Francis, 2021.
    Publicado
  5. Ferreira, Maria Inês; Cova, Tânia; Paixão, José A.; Pais, Alberto; Vitorino, Carla. "Coprecipitation synthesis, stabilization, and characterization of oleic acid-coated iron oxide nanoparticles for magnetically oriented hybrid system vectorization". In Magnetic Nanoparticle-Based Hybrid Materials, 273-301. Elsevier, 2021.
    Publicado • 10.1016/b978-0-12-823688-8.00033-8
  6. Cova, Tânia F. G. G.; Nunes, Sandra C.C.; Cova, Tânia Firmino Guerra Guerreiro da. "Modelling and Simulation of Nanosystems for Delivering Drugs to the Brain". In Nanoparticles for Brain Drug Delivery, 427-451. New York, Estados Unidos: Jenny Stanford Publishing, 2020.
    Publicado • 10.1201/9781003119326-17
  7. Cova, Tânia F.G.G.; Cruz, Sandra M.A.; Valente, Artur J.M.; Abreu, Paulo E.; Marques, Jorge M.C.; Pais, Alberto A.C.C.. "Aggregation of Cyclodextrins: Fundamental Issues and Applications". In Cyclodextrin - A Versatile Ingredient. n.a.: InTech, 2018.
    Publicado • 10.5772/intechopen.73532
  8. Cova, Tânia F.; Nunes, Sandra C.; Milne, Bruce F.; Jorge, Andreia F.; Pais, Alberto C.. "Modeling Soft Supramolecular Nanostructures by Molecular Simulations". In Molecular Dynamics. Portugal: InTech, 2018.
    Publicado • 10.5772/intechopen.74939
  9. Cova, Tânia F.G.G.; Almeida, João A. S.; Pais, Alberto A. C. C.; Formosinho, Sebastião J.. "Uma visão das culturas do mundo através da ciência: o papel do conhecimento tácito". In Interdisciplinaridade e Universidade, 71-95. Imprensa da Universidade de Coimbra, 2013.
    Publicado • 10.14195/978-989-26-1239-3_2
Edição de livro
  1. Artificial intelligence applied to drug product lifecycle (contract: https://www.dropbox.com/s/owspqk6ivb9z750/Elsevier_Please_Sign_Contract_%28639580%29_for_%20%281%29.pdf?dl=0). Elsevier. 2023.
    Editor
Manual
  1. Cova, Tânia F. G. G.; Pais, Alberto A. C. C.; Pereira, Jorge L. G. F. S. C.. Statistical and Multivariate Analysis in R - E-learning Course. Coimbra, Portugal. 2015.
Poster em conferência
  1. Dário Cartaxo ; Francisco Fonseca; Ana Patrício; Sandra Nunes; Tânia F. Cova ; Alberto A. C. C. Pais. "Molecular descriptors for the characterization of antibiotics: combining machine learning and ab initio Calculations". Trabalho apresentado em 8th Portuguese Young Chemists Meeting, 8PYCheM, 2023.
  2. Tânia F. Cova; Sandra Nunes; Soraia Assis ; Alberto A. C. C. Pais. "Characterizing Emerging Psychoactive Drugs by Mining Chemical Data and using Molecular Simulations". Trabalho apresentado em 8th Portuguese Young Chemists Meeting, 8P, 2023.
  3. Sandra C.C. Nunes; Tânia F.Cova; Ana Luísa C. Ferreira ; Alberto A.C.C. Pais. "DNA Nanostructures as Antimicrobial Drug Nanocarriers: A Molecular Dynamics Study". Trabalho apresentado em 8th Portuguese Young Chemists Meeting, 8PYCheM, 2023.
  4. Cova, Tânia Firmino Guerra Guerreiro da; Ferreira, Cláudia F.; Alberto A. C. C. Pais. "Predicting molecular similarity and toxicity using machine learning as a playground". Trabalho apresentado em Chemical Science Symposium 2020 - How can machine learning and autonomy accelerate chemistry?, 2020.
  5. Nunes, Sandra C. C.; Cova, Tânia Firmino Guerra Guerreiro da; Pais, A. A. C. C.. "Monte Carlo Simulations on biological inspired systems: the role of electrostatics". Trabalho apresentado em Okinawa Colloids 2019, 2019.
  6. Miranda, Margarida; Cova, Tânia Firmino Guerra Guerreiro da; Augusto, Cátia; Pais, Alberto A. C. C.; Catarina Joana Dias Neto Pratas Cardoso; Carla Sofia Pinheiro Vitorino. Autor correspondente: Carla Sofia Pinheiro Vitorino. "Batch-to-batch variability of semisolid topical drug products". Trabalho apresentado em Okinawa Colloids 2019, 2019.
  7. Cova, Tânia Firmino Guerra Guerreiro da; Nunes, Sandra C. C.; Pais, A. A. C. C.. "Modeling of drug recognition by cyclodextrin-based nanostructures: a computational approach". Trabalho apresentado em International conference on medical, biological and pharmaceutical sciences, 2019.
  8. Cova, Tânia Firmino Guerra Guerreiro da; Sousa, João José; Silva, Jessica; Mendes, Maria; Basso, João; Pais, A. A. C. C.; Vitorino, Carla. "Unstructured formulation data analysis for the optimization of lipid nanoparticle drug delivery vehicles". Trabalho apresentado em 688th International Conference on Medical, Biological and Pharmaceutical Sciences, 2019.
  9. Cova, Tânia Firmino Guerra Guerreiro da; Cobo, A; Bento, D.; Cova, Tânia Firmino Guerra Guerreiro da; Nunes, Sandra C. C.; Valente, Artur; Pais, A. A. C. C.. "PVA-NLC films for transdermal drug delivery". Trabalho apresentado em RICI8 – 8th Iberian Meeting on Colloids and Interfaces, 2019.
  10. Cova, Tânia Firmino Guerra Guerreiro da; Nunes, Sandra C. C.; Pais, Alberto A. C. C.. "Volume and substituent effects in molecular recognition: a step forward in modulating soft supramolecular nanostructures by free energy calculations". Trabalho apresentado em XIII Encontro Nacional de Química-Física (II Simpósio de Química Computacional), 2018.
  11. Cova, Tânia Firmino Guerra Guerreiro da; Mendes, Maria; Pais, Alberto A. C. C.; Sousa, João J.; Vitorino, Carla; Miranda, Alexandra. "Modeling of nanoparticle surface charge for targeting glioblastoma". Trabalho apresentado em XII Spanish-Portuguese Conference on Controlled Drug Delivery, 2018.
  12. Sousa, João J.; Mendes, Maria; Cova, Tânia Firmino Guerra Guerreiro da; Vitorino, Carla; Pais, Alberto A. C. C.. "Modeling of nanoparticle surface charge for glioblastoma treatment". Trabalho apresentado em 13th International Conference on Advanced Materials and Nanotechnology, 2017.
  13. Cova, Tânia Firmino Guerra Guerreiro da; Nunes, Sandra C. C.; Pais, Alberto A. C. C.. "The concerted action involving conformation and desolvation that ma- kes water-soluble bambusurils unique anion cages". Trabalho apresentado em VII Iberian Meeting on Colloids and Interfaces, 2017.
  14. Miranda, Alexandra; Mendes, Maria; Cova, Tânia Firmino Guerra Guerreiro da; Sousa, João J.; Vitorino, Carla; Pais, Alberto A. C. C.. "Serine based gemini lipid nanoparticles for glioblastoma treatment". Trabalho apresentado em VII Iberian Meeting on Colloids and Interfaces, 2017.
  15. Miranda, Alexandra; Cova, Tânia Firmino Guerra Guerreiro da; Mendes, Maria; Vitorino, Carla; Sousa, João J.; Pais, Alberto A. C. C.. "Molecular dynamics simulations on glioblastoma: Blood brain barrier mimicry and interactions with chemotherapeutic drugs". Trabalho apresentado em VII Iberian Meeting on Colloids and Interfaces, 2017.
  16. Nunes, Sandra; Tavares, Nélia C.T.; Cova, Tânia Firmino Guerra Guerreiro da; Murtinho, Dina; Serra, M.E.S.; Pinho e Melo, T.M.V.D.; Pais, A. A. C. C.. "Molecular Dynamic Studies on new substituted thiazolidines". Trabalho apresentado em XII Encontro Nacional de Química-Física/I Simpósio de Química Computacional, 2016.
  17. Tavares, N. C. T.; Nunes, Sandra C. C.; Cova, Tânia Firmino Guerra Guerreiro da; Murtinho, D.; Serra, M. E. S.; Pinho e Melo, T. M. V. D; Pais, Alberto A. C. C.. "Molecular Dynamics Studies on Substituted Thiazolidines". Trabalho apresentado em 12º Encontro Nacional de Química-Física / 1º Simpósio de Química Computacional, 2016.
  18. Cova, Tânia Firmino Guerra Guerreiro da; Nunes, Sandra C. C.; Pinho e Melo, T. M. V. D; Pais, Alberto A. C. C.. "Properties and patterns in host-guest systems: a closer look at glycoluril-based hosts for anions". Trabalho apresentado em 12º Encontro Nacional de Química-Física / 1º Simpósio de Química Computacional, 2016.
  19. Encarnação, T.; Arranja, Cláudia T.; Cova, Tânia Firmino Guerra Guerreiro da; Pais, Alberto A. C. C.; Campos, Maria G.; Sobral, Abílio J. F. N.; Burrows, Hugh D.. "New BODIPY derivative fluorescent probe for rapid quantification of lipids in microalgae". Trabalho apresentado em 20th International Symposium on Surfactants in Solution, SIS2014, 2014.
  20. Encarnação, T.; Cova, Tânia Firmino Guerra Guerreiro da; Pereira, Jorge L.G.F.S.C.; Pais, Alberto A. C. C.. "Imagiology: a chemometrics approach". Trabalho apresentado em SPQ-Analítica-2014, 2014.
  21. Rosa, M. J.; Gramacho, Sílvia; Cova, Tânia Firmino Guerra Guerreiro da; Pinheiro, Marta; Pais, Alberto A. C. C.. "Characterization of rosin samples using GC-MS and chemometrics analysis: origin and composition". Trabalho apresentado em 4th Portuguese Young Chemists Meeting, 2014.
  22. Cova, Tânia Firmino Guerra Guerreiro da; Jarmelo, Susana; Rondão, R.; de Melo, J. Sérgio Seixas; Pais, Alberto A. C. C.; Formosinho, Sebastião J.. "Multivariate Analysis of Portuguese Scientific Productivity, with a fo- cus in Chemistry". Trabalho apresentado em XXIII Encontro Nacional da SPQ, 2013.
  23. Lopes, A. C.; Cova, Tânia Firmino Guerra Guerreiro da; Pais, Alberto A. C. C.; Pereira, Jorge L.G.F.S.C.; Colaço, B.; Cabrita, A. M. S.. "Improving discrimination in the grading of rat mammary tumors using low-dimensional mapping of histopathological observations, and ad- vanced modeling techniques". Trabalho apresentado em 17th ECCO - 38th ESMO -32ndESTRO European Cancer Congress, Reinforcing multidisciplinarity, 2013.
Recurso online
  1. Miranda, Ana; Basso, João; Cova, Tânia F.; Nunes, Sandra C. C.; Sousa, João J.; Pais, Alberto A. C. C.; Vitorino, Carla. Outside Front Cover, Gels, Volume 4, Issue 3 (September 2018). 2018. https://www.mdpi.com/2310-2861/4/3?view=abstract&listby=date&page_no=1.
  2. Alagia, Adele; Jorge, Andreia F.; Avinó, Anna; Cova, Tânia Firmino Guerra Guerreiro da; Crehuet, Ramon; Grijalvo, Santiago; Pais, Alberto A. C. C.; Eritja, Ramon. Inside back cover. 2018. http://dx.doi.org/10.1039/c8sc90043d.
    10.1039/c8sc90043d
Tese / Dissertação
  1. Sagar, Vidya. "Simulation of Supramolecular Systems for Drug Delivery Based on Inclusion Complexes". Doutoramento, Faculty of Sciences and Technology of the University of Coimbra, 2018. https://www.dropbox.com/s/866j6otae8fhkeh/Tese_TaniaCova.pdf?dl=0.
    xxxx

Propriedade Intelectual

Patente
  1. Cova, Tânia Firmino Guerra Guerreiro da. 2021. "WO/2021/111364A1 - Dual nanostructured lipid carrier as a multifunctional platform for brain tumor therapy. Inventors: C. Vitorino, A. Pais, J. Sousa, A. F. Falcão, A Fortuna, T. Cova, S. Nunes, J. Torres, M. Mendes, A. Almeida, L. Gonçalves. Applicants: Univ. Coimbra and Faculty of Pharmacy of Univ. Lisbon, Portugal. https://tinyurl.com/Patent21".
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/11/22 Cyclodextrin complexes: computational insights into structure and recognition behavior for enhanced pharmaceutical and environmental applications XXVII Encontro Luso Galego de Química
Fundação Dr. António Cupertino de Miranda (Porto, Portugal)
2023/11/22 How simple models in Monte Carlo simulations can complement and expand the knowledge of Biomolecule-Based Drug Delivery Systems XXVII Encontro Luso Galego de Química
Fundação Dr. António Cupertino de Miranda (Porto, Portugal)
2023/09/20 Breaking Through the Blood-Brain Barrier: The Synergy of Machine Learning and Molecular Simulations in Designing Cell-Penetrating Peptides for Glioblastoma Nanoparticle Therapy International Meeting Molecules 4 Life
UTAD, Vila Real (Vila Real, Portugal)
2023/09/20 Efficient models for Monte Carlo simulations applied to different biomolecules-based drug delivery systems I International Meeting Molecules 4 Life
UTAD (Vila Real, Portugal)
2023/09/20 Addressing hard-to-access brain tumors using a chemo-photothermal nanotechnology I International Meeting Molecules 4 Life
UTAD (Vila Real, Portugal)
2023/07/24 Prediction of molecular properties of metal-containing drugs using machine learning models XXVIII Encontro Nacional da SPQ
Universidade de Aveiro (Aveiro, Portugal)
2023/07/24 Electrostatics and biomolecules-based drug delivery systems XXVIII Encontro Nacional da SPQ
Universidade de Aveiro (Aveiro, Portugal)
2023/07/24 Advancing brain tumor therapy with solid lipid nanoparticles XXVIII Encontro Nacional da SPQ
Unversidade de Aveiro (Aveiro, Portugal)
2023/05/17 Strategies to address hard-to-access brain tumors using solid lipid nanoparticles 8th Portuguese Young Chemists Meeting, 8PYCheM
UTAD (Vila Real, Portugal)
2021/08/15 Computational design of peptide-carbohydrate conjugates to improve drug recognition and tumor targeting International Symposium on Biomedical Engineering and Computational Biology (BECB 2021)
2020/07/02 Computational Modeling Of Aptamer- And Peptide-carbohydrate Conjugates As A New Strategy To Improve Drug Recognition And Tumor Targeting Controlled Release Society, Annual Meeting and Exposition, Virtual Meeting, Las Vegas, Nevada, USA
Controlled Release Society (CRS) (Las Vegas, Estados Unidos)
2019/11/05 Engineered cationic ultra-small lipid nanoparticles for glioblastoma treatment Okinawa Colloids 2019
Division of Colloid and Surface Chemistry, The Chemical Society of Japan (Nago, Okinawa, Japão)
2019/11/05 Computational modeling of drug recognition and free-energy patterns in cyclodextrin-based nanostructures Okinawa Colloids 2019
Division of Colloid and Surface Chemistry, The Chemical Society of Japan (Nago, Okinawa, Japão)
2019/09/05 The many facets of cyclodextrin complexes 13th International Meeting of the Portuguese Carbohydrate Group - GLUPOR 13
i3S - Instituto de Investigação e Inovação em Saúde (Porto, Portugal)
2019/07/18 Unveiling the effect of structural flexibility and cavity space filling on the molecular recognition of cyclodextrins by free-energy calculations RICI8 – 8th Iberian Meeting on Colloids and Interfaces
Univ. Aveiro (Aveiro, Portugal)
2019/07 Lipid nanoparticles in drug delivery: What have we learned so far? 8th Iberian Meeting on Colloids and Interfaces: RICI 8
Dep. of Chemistry of Univ.. Aveiro; CICECO-Aveiro Institute of Materials, and SPQ (Aveiro, Portugal)
2018/10/09 Free-energy patterns in soft supramolecular nanostructures for drug delivery International Conference on Drug Delivery and Nanomedicine
(Stockholm, Suécia)
2018/06/04 Beyond charge density: what dictates polyelectrolyte adsorption upon multicomponent responsive surfaces? III Encontro Nacional de Química-Física (II Simpósio de Química Computacional)
Sociedade Portuguesa de Química (Faro, Portugal)
2018/03/12 Polarizable surfaces, crowders and polyelectrolyte adsorption International Workshop: Polyelectrolytes in Chemistry, Biology and Technology
(Singapura)
2017/11/09 Modulating supramolecular nanostructures cross-linked by hyaluronic acid derivatives for drug delivery III International Conference on Clinical Sciences and Drug Discovery
(Washington D. C., Estados Unidos)
2017/07/04 Modulating supramolecular nanostructures: a free-energy oriented approach VII Iberian Meeting on Colloids and Interfaces
(Madrid, Espanha)
2016/06/22 Host-guest complexes: features and factors 12º Encontro Nacional de Química-Física / 1º Simpósio de Química Computacional
(Portugal)
2014/12/17 Characterization of Chemistry, Biochemistry and Chemical Engineering Departments in the Portuguese Universities XVIII Congress of the Portuguese Biochemical Society
(Coimbra, Portugal)
2014/04/29 How many people contribute to Chemistry in the University of Coimbra? A comparison with other Portuguese and foreign (MIT, Lund) universities 4º PYCheM- 4th Portuguese Young Chemists Meeting
(Coimbra, Portugal)
2014/04/14 BODIPY staining: a rapid method for lipid quantification in microalgae SPQ-Analítica
(Coimbra, Portugal)
2014/02/27 Chemometrics tools for medical diagnosis and epidemiology Chemistry Conference for Young Scientists - ChemCYS
(Blankenberg, Bélgica)
2013/06/26 Non-random adsorption of polyelectrolytes in regularly charged surfaces: From single chain to multichain deposition 5th Iberian Meeting on Colloids and Interfaces, RICI5
(Donostia-San Sebastián, Espanha)
2013 Search for Articles and access to different Databases NEQ Workshop
Department of Chemistry, University of Coimbra (Coimbra, Portugal)
2013 Geography of Science: Brazil and Portugal Workshop PLI, International Baccalaureate Program - Thinking about experience
Faculty of Psychology and Educational Sciences, University of Coimbra
2011/09/04 Focused Multivariate Analysis for Process optimization European Network for Business and Industrial Statistics - ENBIS
(Coimbra, Portugal)
2010/11/28 Chemometrics tools for medical diagnosis 2nd National Meeting on Medicinal Chemistry
(Coimbra, Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2023/09/01 - Atual Characterization of PFASs using machine learning and electronic structure calculations
Coorientador
Chemistry (Mestrado)
Department of Chemistry, Faculty of Sciences and Technology, University of Coimbra, Portugal
2023/09/01 - Atual Antibiotics: identification and characterization using machine learning as a playground
Coorientador
Chemistry (Mestrado)
Department of Chemistry, Faculty of Sciences and Technology, University of Coimbra, Portugal
2023/07/01 - 2024/01/31 Computational study of the interaction between organic molecules with anticancer activity and biological membranes
Coorientador
Chemistry (Doutoramento)
PROMOCS Laboratory, Department of Chemistry and Chemical Technologies, University of Calabria, Itália
2023/02/01 - 2023/07/31 Development of a machine learning models to predict molecular properties of Pt(IV) and Pt(II)-based complexes
Coorientador
Chemistry (Doutoramento)
PROMOCS Laboratory, Department of Chemistry and Chemical Technologies, University of Calabria, Itália
2021/01/03 - 2021/09 Optimizing processes for solid lipid-based nanoparticle characterization for anticancer drug delivery
Orientador
Medicinal Chemistry (Licenciatura/Bacharelato)
Universidade de Coimbra, Portugal
2020/09/01 - 2021/09 Characterizing the emerging psychoactive drugs by mining data from chemical databases and molecular simulations
Orientador
Forensic Chemistry (Mestrado)
Universidade de Coimbra, Portugal
2020/01/04 - 2021/07 Computational studies for the design of DNA-based vehicles for antimicrobial molecules.
Orientador
Medicinal Chemistry (Licenciatura/Bacharelato)
2020/01/15 - 2020/07 Computational modeling of drug recognition and free-energy patterns insupramolecular nanostructures based on host-guest interactions
Orientador
Chemistry (Licenciatura/Bacharelato)
Department of Chemistry, Faculty of Sciences and Technology, University of Coimbra, Portugal
2020/01/01 - 2020/07 In silico design of hybridnanoparticles for transdermal applications: from cosmetics to advancedmelanoma.
Orientador
Medicinal Chemistry (Licenciatura/Bacharelato)
Department of Chemistry, Faculty of Sciences and Technology, University of Coimbra, Portugal
2020/01/01 - 2020/07 Computational design of DNA hydrogels to removing micropollutants from water environments
Orientador
Chemistry (Licenciatura/Bacharelato)
Department of Chemistry, Faculty of Sciences and Technology, University of Coimbra, Portugal
2019/10/01 - 2019/12/31 Development and optimization of DNA hydrogels for removing micropollutants in competitive aquatic environments using computational modeling and data science tools. BIC MCF#5 - L616633
Orientador de João Victor Rocha Gonçalves
Undergraduate student (Iniciação científica)
Department of Chemistry, Faculty of Sciences and Technology, University of Coimbra, Portugal
2019/10/01 - 2019/12/31 Development and optimization of DNA hydrogels for removing micropollutants in competitive aquatic environments. BIC MCF#5 - L616633
Orientador de Carolina Valente Domingos
Undergraduate student (Iniciação científica)
Department of Chemistry, Faculty of Sciences and Technology, University of Coimbra, Portugal
2019/10/01 - 2019/12/31 Development of DNA-based nanostructures for drug and gene delivery using atomistic and coarse-grained models. BIC MCF#6 - L616634
Coorientador de Paulo Nunes Barradas
Undergraduate student (Iniciação científica)
Department of Chemistry, Faculty of Sciences and Technology, University of Coimbra, Portugal
2019/10/01 - 2019/12/31 Development of DNA-based nanostructures for drug and gene delivery. BIC MCF#6 - L616634
Coorientador
Undergraduate student (Iniciação científica)
Department of Chemistry, Faculty of Sciences and Technology, University of Coimbra, Portugal
2018/09/01 - 2019/09/09 Comparação de packages R para a análise não compartimental de dados farmacocinéticos
Coorientador
Degree in Medicinal Chemistry (Licenciatura/Bacharelato)
Department of Chemistry, Faculty of Sciences and Technology, University of Coimbra, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2023/11/01 - 2024/06/26 Member of the Organizing committee of RICI X - The 10th Iberian Meeting on Colloids and Interfaces (2024/06/23 - 2024/06/26)
Conferência (Membro da Comissão Organizadora)
Coimbra Chemistry Centre, Faculty of Sciences and Technology, University of Coimbra, Portugal
2021/09/15 - 2021/12/15 Member of the Organizing committee of the Coimbra Chemistry Centre Day 2021 (2021/12/15 - 2021/12/15)
Conferência (Membro da Comissão Organizadora)
Coimbra Chemistry Centre, University of Coimbra, Portugal
2019/06/19 - 2019/06/19 Workshop on Nanotechnology and brain drug delivery. https://www.uc.pt/ffuc/article?key=a-bb6d755baa (2019/06/19 - 2019/06/19)
Oficina (workshop) (Membro da Comissão Organizadora)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/10/19 - 2018/10/19 Workshop on Viruses and Nucleic Acids, Invited speakers: Ramon Eritja (University of Barcelona, Spain), Avinoam Ben-Shaul (The Hebrew University of Jerusalem, Israel) and William Gelbart (UCLA College, USA), https://www.dropbox.com/s/wqsmjmkvu6s2dcx/Workshop_DQ_19Out%20%281%29.pdf?dl=0 (2018/10/19 - 2018/10/19)
Oficina (workshop) (Membro da Comissão Organizadora)
Coimbra Chemistry Centre, University of Coimbra, Portugal
2015/07/01 - 2015/07/03 Member of the organizing committee of the "XXIV Encontro Nacional da Sociedade Portuguesa de Química" (2015/07/01 - 2015/07/03)
Encontro (Membro da Comissão Organizadora)
2014/06/22 - 2014/06/27 Member of the organizing committee of the 20th International Symposium on Surfactants in Solution (2014/06/22 - 2014/06/27)
Simpósio (Membro da Comissão Organizadora)

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2020/09/22 - 2020/09/24 European Research & Innovation Days
Exposição
European Commission
European Commission, Bélgica
2018/04/19 - 2018/04/20 World Health Summit Regional Meeting 2018
Congresso
World Health Summit Regional Meeting 2018
2012 - 2012 European Association of Cancer Research (EACR) Symposium, Darwinian evolution and clonal heterogeneity in human cancer: biological and clinical implications
Simpósio
2010/04/21 - 2010/04/23 2nd Portuguese Young Chemists Meeting
Encontro
2nd Portuguese Young Chemists Meeting

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2023/09 Spectroscopic characterization of carbohydrates and development of chemometrics models for their identification in mixtures
Arguente principal
Inês Freitas Cardoso (Outro)
Department of Chemistry, Faculty of Sciences and Technology, University of Coimbra, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2018/02/21 - 2018/02/22 III Scientific Meeting NEQ/AAC CQC, University of Coimbra

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2023/10/01 - Atual International Journal of Molecular Sciences MDPI
2023/06/01 - Atual Frontiers in Chemistry Frontiers
2019/12/01 - 2020/11/30 Processes MDPI
2019/01/25 - 2019/10/31 International Journal of Molecular Science (IJMS), Section Materials Science (1422-0067) MDPI

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2023/12/01 - Atual Expert evaluator for the National Science Centre Poland
Avaliador

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2023/04/01 - Atual Member of the Topic Advisory Panel of the International Journal of Molecular Sciences – IJMS (MDPI) for the “Molecular Informatics” section

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2022/03/25 - 2022/06/21 Statistical and Multivariate Analysis in R - 11th ed. Course / Discipline taught in 2022 (Outros)
2021/10 - 2022/01 Statistical and Multivariate Analysis in R - 10th ed. Course / Discipline taught in 2021 Coimbra Chemistry Centre, University of Coimbra, Portugal
2020/09/07 - 2020/09/08 Summer School on Machine Learning and Big Data with Quantum Computing (Outros) University of Porto, Portugal
2020/03/23 - 2020/06/19 Statistical and Multivariate Analysis in R - 7th ed. http://www.ed.uc.pt/educ/curso?id=182 (Outros) Universidade de Coimbra, Portugal
2019/10/21 - 2020/01/24 Statistical and Multivariate Analysis in R - 6th ed. http://www.ed.uc.pt/educ/curso?id=182 Statistical and Multivariate Analysis in R (Outros) Universidade de Coimbra, Portugal
2019 - 2019 Statistical and Multivariate Analysis in R - 5th edition http://www.ed.uc.pt/educ/curso?id=157 (Outros) University of Coimbra, Portugal
2018/03/13 - 2018/07/16 Statistical and Multivariate Analysis in R - 4th ed. Statistical and Multivariate Analysis in R (Outros) Universidade de Coimbra, Portugal
2016/10/11 - 2017/01/16 Statistical and Multivariate Analysis in R - 3rd ed. Statistical and Multivariate Analysis in R (Outros) Universidade de Coimbra, Portugal
2015/10/21 - 2016/01/26 Statistical and Multivariate Analysis in R - 2nd ed. Statistical and Multivariate Analysis in R (Outros) Universidade de Coimbra, Portugal
2015/04/22 - 2015/07/15 Statistical and Multivariate Analysis in R - 1st ed. Análise Estatística e Multivariada em R (Outros) Universidade de Coimbra, Portugal
2013 - 2013 Data processing and interpretation, Advanced experimental courses for high-school students and teachers (Ensino secundário)
2012/01 - 2012/01 Data processing and interpretation, Advanced experimental courses for high-school students and teachers (Ensino secundário)

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2020/07/31 - Atual Management Committee (MC) Substitute [CA19145 PT] to COST Action CA19145 - European Network for assuring food integrity using non-destructive spectral sensors.
Membro

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2023/06 - Atual Member of the jury in the competitive procedure for awarding a postgraduate research grant - doctorate in Health Sciences, within the scope of the NanoPEP project, “Calcitonin Interaction- Receptor Promoted by Peptide-Guided Nanoparticles as a New Approach for Treatment of Glioblastoma” with reference IT137-23-242 Universidade de Coimbra Faculdade de Farmácia, Portugal
2022/09 - Atual Member of the evaluation jury of Seminar I of MST Sultana Razia, entitled “Rethinking the design of Transdermal Patches using 3-Dimensional Printing”, PhD in Pharmaceutical Sciences, Doctoral Program in Pharmaceutical Sciences, Faculty of Pharmacy, University of Coimbra Universidade de Coimbra Faculdade de Farmácia, Portugal
2022/07 - Atual Member of the evaluation jury for the Francisco Fonseca Laboratory Internship, entitled “Characterization of antibacterial molecules through electronic structure calculations and computational learning methods” Degree in Chemistry, Department of Chemistry, University of Coimbra, July 2022
2021/09 - Atual Membro do júri de avaliação do Estágio Laboratorial de Ana Luísa Casanova Ferreira, intitulado “Nanoestruturas de ADN como transportadores de fármacos antimicrobianos: Um estudo de Dinâmica Molecular”, Licenciatura em Química Medicinal, Departamento de Química, Universidade de Coimbra, Setembro 2021
2021/09 - Atual Member of the evaluation jury for the Cláudia Filipa Soares Ferreira Scientific Project titled “Mycotoxins: identification and characterization using machine learning as a playground”, Master in Chemistry, Department of Chemistry, University of Coimbra, September 2021
2021/09 - Atual Membro do júri de avaliação do Estágio Laboratorial de Mariana Simões de Melo, intitulado “Optimizing processes for solid lipid-based nanoparticle characterization for anticancer drug delivery”, Licenciatura em Química Medicinal, Departamento de Química, Universidade de Coimbra, Setembro 2021
2021/07 - Atual Membro do júri de avaliação do Projecto Científico de Soraia Filipa Drysdale Assis intitulado “Characterizing the emerging psychoactive drugs by mining data from chemical databases and molecular simulations”, Mestrado em Química Forense, Departamento de Química, Universidade de Coimbra, Setembro 2021
2021/07 - Atual Member of the evaluation jury for Joana Raquel dos Santos's Laboratory Internship report Simões, entitled “Emerging pollutants and structural similarity: a computational study”, Degree in Chemistry, Department of Chemistry, University of Coimbra, July 2021
2020/07 - Atual Member of the evaluation jury for Ana Carolina Ramos Quinteiro's Laboratory Internship entitled “Modeling and computational simulation of a system for managing drugs based on inclusion complexes”, Degree in Chemistry, Department of Chemistry, University of Coimbra, July 2020
2020/07 - Atual Member of the evaluation jury for Francisca Dias Pereira's Laboratory Internship entitled “Computational design of DNA hydrogels to removing micropollutants from water environments”, Degree in Chemistry, Department of Chemistry, University of Coimbra, July 2020
2023 - 2023 Expert evaluator for the European Commission Horizon Europe programme - MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01)
2023 - 2023 Reviewer - Carbohydrate Polymers - Ref: CARBPOL-D-23-05950R1
2022/02/15 - 2022/03/08 Reviewer - Journal of Computational Chemistry - Ref: JCC-22-0078
2021/11/04 - 2022/02/11 Expert evaluator for the European Commission Horizon Europe programme - MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01) European Research Executive Agency, Bélgica
2022 - 2022 Expert evaluator for the European Commission Horizon Europe programme - MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01)
2021/11/12 - 2021/11/22 Reviewer - Polysaccharides (MDPI) Manuscript ID: polysaccharides-1443730
2021/10/15 - 2021/11/05 Reviewer - Journal of Molecular Liquids (Elsevier)- Manuscript Number: MOLLIQ-D-21-06560
2020/12/16 - 2021/01/19 Reviewer - Journal of Molecular Liquids - Manuscript ID: MOLLIQ-D-20-00985
2020/07/13 - 2020/07/23 Reviewer - Applied Sciences (MDPI) - Manuscript ID: applsci-878262
2020/06/12 - 2020/06/26 Reviewer - Journal of Molecular Liquids - Manuscript ID: MOLLIQ_2020_2242
2020/03/05 - 2020/03/26 Reviewer - Journal of Molecular Liquids (Elsevier) - Manuscript ID: MOLLIQ_2020_1244
2019/12/19 - 2019/12/29 Reviewer - Manuscript ID: molecules-679889
2019/12/17 - 2019/12/27 Reviewer - Molecules (MDPI) Manuscript ID: molecules-603858
2019/07/08 - 2019/07/18 Reviewer - Pharmaceutics (MDPI) - Manuscript ID: pharmaceutics-545033
Distinções

Prémio

2018 Best Oral Presentation Award
International Conference on Drug Delivery and Nanomedicine, IAAM, Suécia
2018 EIT Health DPhil/PhD Transition Fellowship
EIT Health, Portugal
2017 Best Poster Award
VII Iberian Meeting on Colloids and Interfaces, Portugal
2012 Academic Merit Scholarship 2011/2012, FCTUC, UC
Faculty of Sciences and Technology of the University of Coimbra, Portugal
2012 Top 3% of Students Award 2011/2012
Universidade de Coimbra, Portugal
2011 Top 3% of Students Award 2010/2011
Universidade de Coimbra, Portugal