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Martina Dourado Gonçalves graduated in Medicinal Biotechnology at the School of Health of the Polytechnic Institute of Porto in 2021 and obtained a master's degree in Oncology at the Abel Salazar Biomedical Sciences Institute of University of Porto in 2023. During her master's, Martina developed her dissertation at the Experimental Pathology and Therapeutics Group (IPO-Porto), under the supervision of Doctor Andreia Peixoto, Doctor José Alexandre Ferreira and Professor Lúcio Lara Santos. Her dissertation focused on characterizing the functional glycoproteomics implications of gastric cancer cells expressing short-chain O-glycans. Throughout her master's degree, she developed expertise in a wide range of cell culture methodologies, including CRISPR/Cas9 gene editing, flow cytometry, immunocytochemistry and functional assays in vitro. Additionally, she acquired proficiency in molecular biology techniques such as SDS-Page, Western Blot, Reverse Transcription PCR, and extraction of DNA, RNA, and proteins from cell lines. Martina also delved into proteomics and glycoproteomics techniques, including advanced mass spectrometry. Throughout her academic journey, she has consistently demonstrated a strong commitment to scientific dissemination, presenting her findings through oral communications and poster presentations. Notably, she received an honorable mention at the 1st Young Researcher's Day and an award for the best oral presentation at IJUP 2024. Moreover, she has participated in other projects that have resulted in the publication of five papers. Martina has a strong passion for sharing science, which has driven her to participate in several scientific dissemination events focused on younger audiences. In this context, she has been actively involved in workshops and the development of educational activities, fostering a deeper understanding and engagement with science.
Identification

Personal identification

Full name
Martina Dourado Gonçalves

Citation names

  • Dourado-Gonçalves, Martina
  • Gonçalves, Martina

Author identifiers

Ciência ID
C410-3A72-CC85
ORCID iD
0009-0004-6311-3990

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
  • Medical and Health Sciences - Clinical Medicine - Oncology
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Education
Degree Classification
2024/09/09 - 2024/09/20
Concluded
Laboratory Animal Science Course (Curso de Especialização Tecnológica)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Federation of European Laboratory Animal Science Associations, Belgium

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2024/04/04 - 2024/04/04
Concluded
Citometria de Fluxo: conceitos e aspetos metodológicos, desenho de painéis multiparamétricos e utilização prática de um citómetro de fluxo (Outros)
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2024 - 2024
Ongoing
CLIC (Outros)
Universidade de Aveiro Associação para a Formação Profissional e Investigação, Portugal
2021/09/20 - 2023/12/12
Concluded
Oncologia (Mestrado)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
"Functional glycoproteomics characterization of gastric cancer cells expressing immature O-glycans" (THESIS/DISSERTATION)
18
2018/09 - 2021/07/27
Concluded
Biotecnologia Medicinal (Licenciatura)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
"Xenobiotic-Free Isolation of Umbilical Cord Mesenchymal Stem Cells" (THESIS/DISSERTATION)
17
Affiliation

Science

Category
Host institution
Employer
2023/12/13 - 2025/02/28 Research Trainee (Research) Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
Projects

Grant

Designation Funders
2024/05 - 2024/12 RESOLVE: Rational Design of Multivalent Glycocode-Inspired Nanovaccines for Gastric Cancer Immunotherapy
PTDC/MED-OUT/2512/2021
Research Fellow
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Universidade de Aveiro, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Conference poster
  1. Dourado-Gonçalves, Martina; Freitas, Rui; Ferreira, Dylan; Relvas-Santos, Marta; Paulo, Paula; Santos, Lúcio Lara; Andreia Filipa Ferreira Peixoto; Ferreira, José Alexandre. "Decoding the Functional Glycoproteomic Role of Aberrantly Expressed Short-Chain O-Glycans on Gastric Cancer Cells". Paper presented in Encontro Ciência 2024, 2024.
  2. Peixoto, Andreia; Miranda, Andreia; Ferreira, Dylan; Freitas, Rui; Relvas-Santos, Marta; Ferreira, Eduardo; Cotton, Sofia; et al. "Definindo o papel da glicosilação na agressividade do cancro de bexiga: Impacto do microambiente tumoral". Paper presented in IPO-Porto Summit, 2024.
  3. Dourado-Gonçalves, Martina; Rui Filipe Neves Freitas; Ferreira, Dylan; Relvas-Santos, Marta; Paulo, Paula; Lúcio Lara Santos. "Functional Glycoproteomics Characterization of Gastric Cancer Cells Expressing Immature O-Glycans". Paper presented in 1st Young Researcher's Day, 2023.
  4. Freitas, Rui; Miranda, Andreia; Ferreira, Dylan; Relvas-Santos, Marta; Castro, Flávia; Ferreira, Eduardo; Gaiteiro, Cristiana; et al. "Pre-clinical Validation of a Multivalent CD44 Glycoconjugate Vaccine for Cancer Immunotherapy". Paper presented in 1st Young Researcher's Day, 2023.
  5. Soares, Janine; Ferreira, Dylan; Miranda, Andreia; Relvas-Santos, Marta; Brandão, Andreia; Freitas, Rui; Ferreira, Eduardo; et al. "Glycosylation as a driver of Colorectal cancer aggressiveness". Paper presented in 1st Young Researchers's Day, 2023.
Journal article
  1. Soares, Janine; Eiras, Mariana; Ferreira, Dylan; Santos, Daniela A. R.; Relvas-Santos, Marta; Santos, Beatriz; Gonçalves, Martina; et al. "Stool Glycoproteomics Signatures of Pre-Cancerous Lesions and Colorectal Cancer". International Journal of Molecular Sciences 25 7 (2024): 3722. http://dx.doi.org/10.3390/ijms25073722.
    10.3390/ijms25073722
  2. Freitas, Rui; Ferreira, Eduardo; Miranda, Andreia; Ferreira, Dylan; Relvas-Santos, Marta; Castro, Flávia; Santos, Beatriz; et al. "Targeted and Self-Adjuvated Nanoglycovaccine Candidate for Cancer Immunotherapy". ACS Nano (2024): http://dx.doi.org/10.1021/acsnano.3c12487.
    10.1021/acsnano.3c12487
  3. Ferreira, Eduardo; Ferreira, Dylan; Relvas-Santos, Marta; Freitas, Rui; Soares, Janine; Azevedo, Rita; Afonso, Luís Pedro; et al. "Aberrantly Glycosylated GLUT1 as a Poor Prognosis Marker in Aggressive Bladder Cancer". International Journal of Molecular Sciences 25 6 (2024): 3462. http://dx.doi.org/10.3390/ijms25063462.
    Published • 10.3390/ijms25063462
  4. Freitas, Rui; Miranda, Andreia; Ferreira, Dylan; Relvas-Santos, Marta; Castro, Flávia; Ferreira, Eduardo; Gaiteiro, Cristiana; et al. "A multivalent CD44 glycoconjugate vaccine candidate for cancer immunotherapy". Journal of Controlled Release 367 (2024): 540-556. http://dx.doi.org/10.1016/j.jconrel.2024.01.065.
    Published • 10.1016/j.jconrel.2024.01.065
  5. Cotton, Sofia; Ferreira, Dylan; Relvas-Santos, Marta; Brandão, Andreia; Luis Afonso; Miranda, Andreia; Ferreira, Eduardo; et al. "E-selectin Affinity Glycoproteomics Reveals Neuroendocrine Proteins and the Secretin Receptor as a Poor Prognosis Signature in Colorectal Cancer". (2024): https://febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13733.
    Submitted
Thesis / Dissertation
  1. "Functional Glycoproteomics Characterization of Gastric Cancer Cells Expressing Immature O-Glycans". Master, Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, 2023.
  2. "Xenobiotic-Free Isolation of Umbilical Cord Mesenchymal Stem Cells". Degree, Instituto Politécnico do Porto Escola Superior de Saúde, 2021.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/05/09 Functional Glycoproteomics Characterization of Gastric Cancer Cells Expressing Immature O-Glycans IJUP 2024: Encontro de Investigação Jovem
Universidade do Porto
2023/05/10 Functional Glycoproteomics Characterization of Gastric Cancer Cells Expressing Immature O-Glycans IJUP 2023: Encontro de Investigação Jovem
Universidade do Porto (Porto, Portugal)
2023/02/13 Functional Glycoproteomics Characterization of Gastric Cancer Cells Expressing Immature O-Glycans 7th Symposium of the MSc in Oncology
Instituto Português de Oncologia do Porto Francisco Gentil EPE (Portugal)

Event organisation

Event name
Type of event (Role)
Institution / Organization
2020/09 - 2021/01 Staff member in the LogInBiotech: Scientific event organized by the 3rd year students of the bachelor’s degree in Medicinal Biotechnology (2020/12/18 - 2020/12/18) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2024/09 - 2024/09 Monitor of "Dia Aberto CI-IPOP"
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2024/07/03 - 2024/07/05 Encontro Ciência 2024
Congress
Encontro Ciência 2024
Fundação para a Ciência e a Tecnologia, Portugal

Universidade do Porto, Portugal

Ciência Viva, Portugal
2024/07 - 2024/07 IPO-Porto Research Center Representative at "Junior University"
Universidade do Porto, Portugal
2024/06 - 2024/06 IPO-Porto Research Center Representative at "Biomedical Youth School"
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto, Portugal
2024/05/08 - 2024/05/10 Participation on the IJUP 2024: Encontro de Investigação Jovem
Meeting
IJUP 2024: Encontro de Investigação Jovem
Universidade do Porto, Portugal
2024/04 - 2024/04 RISE and IPO-Porto Research Center Representative at "Mostra da Universidade do Porto"
Exhibition
Universidade do Porto, Portugal
2024/02/12 - 2024/02/12 Participation on the 8th Symposium of the MSc in Oncology 8th Symposium of the MSc in Oncology
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2024 - 2024 6th ENJIO - Encontro de Jovens Investigadores em Oncologia
Congress
6th ENJIO - Encontro de Jovens Investigadores em Oncologia
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro, Portugal
2023/11/09 - 2023/11/09 Participation on the 1st Young Researcher's Day 1st Young Researcher's Day
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2023/05/11 - 2023/05/12 Participation on the 29th Porto Cancer Meeting - Glycosylation in tumour biology and its clinical implications | The cancer bittersweet portrait XXIX Porto Cancer Meeting
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/05/10 - 2023/05/12 Participation on the IJUP 2024: Encontro de Investigação Jovem
Meeting
IJUP 2023: Encontro de Investigação Jovem
Universidade do Porto, Portugal
2023/02/13 - 2023/02/14 Participation on the 7th Symposium of the MSc in Oncology 7th Symposium of the MSc in Oncology
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2022/02/14 - 2022/02/15 Participation on the 6th Symposium of the MSc in Oncology 6th Symposium of the MSc in Oncology
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2021/06/30 - 2021/09/07 Participation on the 2nd edition of H-INNOVA HEALTH INNOVAtion Award 2nd edition of H-INNOVA HEALTH INNOVAtion Award (2020/2021)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019/12/12 - 2019/12/12 Participation in the Biotech In Vivo: Scientific event organized by the 3rd year students of the bachelor’s degree in Medicinal Biotechnology Biotech In Vivo
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2019/05/17 - 2019/05/17 Participation on the 4th Meeting on Medicinal Biotechnology 4th Meeting on Medicinal Biotechnology
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2018/11/30 - 2018/11/30 Participation in the BMeeting: Scientific event organized by the 3rd year students of the bachelor’s degree in Medicinal Biotechnology BMeeting
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
Distinctions

Award

2024 Best Oral Communication Award with "Functional Glycoproteomics Characterization of Gastric Cancer Cells Expressing Immature O-glycans" at 17th IJUP
Universidade do Porto, Portugal

Other distinction

2023 Honorable Mention for Poster Presentation with "Functional Glycoproteomics Characterization of Gastric Cancer Cells Expressing Immature O-glycans" at the 1st Young Researcher's Day
Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal