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Identification

Personal identification

Full name
Alexandra Binnie

Citation names

  • Binnie, Alexandra

Author identifiers

Ciência ID
C212-F6D7-8240
ORCID iD
0000-0003-2969-8177
Education
Degree Classification
2002 - 2007
Concluded
 MD (Doctor)
Major in Medicine
Harvard Medical School, United States
 cum laude
1997 - 2001
Concluded
 Sir William Dunn School of Pathology (Doctor of Philosophy)
Major in Pathology
University of Oxford, United Kingdom
1993 - 1997
Concluded
 Honours Bachelor of Science (Bachelor)
Major in Immunology
University of Toronto Faculty of Arts & Science, Canada
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2023/09/01 - Current Invited Associate Professor (University Teacher) Universidade do Algarve, Portugal
2016 - 2023/08/31 Invited Assistant Professor (University Teacher) Universidade do Algarve, Portugal
2015 - 2016 Assistant Professor (University Teacher) Universidade do Algarve, Portugal
Projects

Grant

Designation Funders
2022/01 - 2027/12 The Life-Threatening Illness National Group (LifTING) Research Training Platform: Spanning Boundaries Between Research and Care
2c75736b9a2936e83a0af6f1cc7ed09d
 Canadian Institutes of Health Research
2022/10 - 2024/09 Lung and Diaphragm Protection in Acute Hypoxemic Respiratory Failure: the LANDMARK II Pilot and Feasibility Randomized Clinical Trial
c87733dd08d3455e8d6a3633de96c06a
 Canadian Institutes of Health Research
2019/10 - 2024/09 EpiGen Marks for Human Sepsis
3c13e4178a3a6bfe3436f7d1a0efb4ea
 Canadian Institutes of Health Research
2021/09 - 2024/08 Factors Influencing Canadian Community Intensive Care Unit (ICU) Participation in Clinical Research: A Qualitative Descriptive Study
PSI 21-26
 Physicians' Services Inc Foundation
2022/02 - 2024/01 COVID-19 And Severe Community-Acquired Pneumonia Dynamic Evaluation Study (CASCADES - ARBS CORONA III)
e0bd15d19cb8e7846db81674f8deae56
 Canadian Institutes of Health Research
2022/10 - 2023/09 Driving Pressure-Limited Ventilation in Hypoxemic Respiratory Failure: the DRIVE RCT
140f5709009f90541c9f18f0782c014b
 Canadian Institutes of Health Research
2022/06 - 2023/05 Canadian Critical Care Trials Group COVID-19 Response: defining critical care capacity in Canada; testing treatments through large-scale adaptive clinical trials; & establishing the evidence base to inform clinical and health system management decisions
3bf8ef57c01b347ecac6eccc68ae89e5
e052b5f6f5f0410638ca723abd930987
 Canadian Institutes of Health Research
2022/03 - 2023/02 Lung and Diaphragm Protection in Acute Hypoxemic Respiratory Failure: the LANDMARK II Pilot and Feasibility Randomized Clinical Trial
1aecc7afa42b6c94889145015d2abc4f
 Canadian Institutes of Health Research
2021/12 - 2022/11 CANCOV2.0: 2-year follow up of the Canadian COVID-19 Prospective Cohort Study
ec3a61f3f940396673ce0926a45faef5
 Canadian Institutes of Health Research
2021/10 - 2022/09 Lung and Diaphragm Protection in Acute Hypoxemic Respiratory Failure: the LANDMARK II Pilot and Feasibility Randomized Clinical Trial
7edf57e1d1448b3ba7ce799b9433142c
 Canadian Institutes of Health Research
2020/10 - 2022/09 Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): A Randomized Controlled Clinical Trial
2cb444b1e335a7e79acf23ce15d050a7
 Canadian Institutes of Health Research
2021/01 - 2022/06 The Canadian Network of COVID-19 Clinical Trials Networks
458236
0ec8c8756bf71a4adefea99c2e2b4480
 Canadian Institutes of Health Research
2021/06 - 2022/05 The Randomized Embedded Multifactorial Adaptive Platform Trial in Community-acquired Pneumonia (REMAP-CAP): Building an International Research Response to Variant COVID-19
5015c2ba6689993cccf1e0dcfd5afb8b
 Canadian Institutes of Health Research
2020/07 - 2021/06 Canadian COVID-19 Prospective Cohort Study (CanCOV)
447643
03bbf667726d5bef556d32ffd9c1bfd2
 Canadian Institutes of Health Research
2015/05 - 2016/04 Epigenetic Profiling in Severe Sepsis (EPSIS)
MC-2015-03
 McLaughlin Centre for Genomic Medicine
2001/04 - 2002/03 PGSB
190163
 Natural Sciences and Engineering Research Council of Canada
1999/04 - 2000/03 PGSA/ESA
158422
179376
139482
 Natural Sciences and Engineering Research Council of Canada
Outputs

Publications

Journal article
  1. Sharma-Oates A; Sullivan J; Pestana D; Dos Santos CC; Binnie A; Lord JM. "Association of Epigenetic Age and Outcome in Critically Ill Patients.". Critical care explorations (2024): http://europepmc.org/abstract/med/38343441.
    10.1097/cce.0000000000001044
  2. Nádia Silva; Ana Teresa Rajado; Filipa Esteves; David Brito; Joana Apolónio; Vânia Palma Roberto; Alexandra Binnie; et al. "Measuring healthy ageing: current and future tools". Biogerontology (2023): https://doi.org/10.1007/s10522-023-10041-2.
    10.1007/s10522-023-10041-2
  3. Quigley N; Binnie A; Baig N; Opgenorth D; Senaratne J; Sligl WI; Zuege DJ; et al. "Modelling the potential increase in eligible participants in clinical trials with inclusion of community intensive care unit patients in Alberta, Canada: a decision tree analysis.". Canadian journal of anaesthesia = Journal canadien d'anesthesie (2023): http://europepmc.org/abstract/med/38129358.
    10.1007/s12630-023-02669-y
  4. Siegal DM; Belley-Côté EP; Lee SF; Hill S; D'Aragon F; Zarychanski R; Rochwerg B; et al. "Small-Volume Blood Collection Tubes to Reduce Transfusions in Intensive Care: The STRATUS Randomized Clinical Trial.". JAMA (2023): http://europepmc.org/abstract/med/37824152.
    10.1001/jama.2023.20820
  5. Kloss P; Lindholz M; Milnik A; Azoulay E; Cecconi M; Citerio G; De Corte T; et al. "Early mobilisation in critically ill COVID-19 patients: a subanalysis of the ESICM-initiated UNITE-COVID observational study.". Annals of intensive care (2023): http://europepmc.org/abstract/med/37962748.
    10.1186/s13613-023-01201-1
  6. LOVIT-COVID Investigators; on behalf of the Canadian Critical Care Trials Group; and the REMAP-CAP Investigators; Adhikari NKJ; Hashmi M; Lamontagne F. "Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.". JAMA (2023): http://europepmc.org/abstract/med/37877585.
    10.1001/jama.2023.21407
  7. Granton J; Novitzky-Basso IN; Binnie A; Mattsson J; DSC Study Group. "Decidual stromal cells for the treatment of severe COVID-19 ARDS.". Intensive care medicine (2023): http://europepmc.org/abstract/med/37968285.
    10.1007/s00134-023-07262-x
  8. REMAP-CAP Investigators; Hills TE; Lorenzi E; Berry LR; Shyamsundar M; Al-Beidh F; Annane D; et al. "Simvastatin in Critically Ill Patients with Covid-19.". The New England journal of medicine (2023): http://europepmc.org/abstract/med/37888913.
    10.1056/nejmoa2309995
  9. COVID-19 Host Genetics Initiative. "A second update on mapping the human genetic architecture of COVID-19.". Nature (2023): http://europepmc.org/abstract/med/37674002.
    10.1038/s41586-023-06355-3
  10. Morgan G; Casalino S; Chowdhary S; Frangione E; Fung CYJ; Haller S; Lapadula E; et al. "Characterizing Risk Factors for Hospitalization and Clinical Characteristics in a Cohort of COVID-19 Patients Enrolled in the GENCOV Study.". Viruses (2023): http://europepmc.org/abstract/med/37632107.
    10.3390/v15081764
  11. Dennis BB; Thabane L; Heels-Ansdell D; Dionne JC; Binnie A; Tsang J; Guyatt G; et al. "Proton pump inhibitors in critically ill mechanically ventilated patients with COVID-19: protocol for a substudy of the Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial.". Trials (2023): http://europepmc.org/abstract/med/37644556.
    10.1186/s13063-023-07589-2
  12. Teo K; Fowler RA; Adhikari NKJ; Rishu A; Tsang JLY; Binnie A; Murthy S; Canadian Critical Care Trials Group. "Time required to initiate a clinical trial in Canada at the onset of the COVID-19 pandemic: an observational research-in-motion study.". CMAJ open (2023): http://europepmc.org/abstract/med/37402556.
    10.9778/cmajo.20220129
  13. Morgan G; Briollais L; Clausen M; Casalino S; Mighton C; Chowdhary S; Frangione E; et al. "Public knowledge of SARS-CoV-2 serological and viral lineage laboratory testing and result interpretation: A GENCOV study cross-sectional survey.". Clinical biochemistry (2023): http://europepmc.org/abstract/med/37406717.
    10.1016/j.clinbiochem.2023.110607
  14. Writing Committee for the REMAP-CAP Investigators; Lawler PR; Derde LPG; van de Veerdonk FL; McVerry BJ; Huang DT; Berry LR; Lorenzi E; Webb SA. "Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial.". JAMA (2023): http://europepmc.org/abstract/med/37039790.
    10.1001/jama.2023.4480
  15. Rajado AT; Silva N; Esteves F; Brito D; Binnie A; Araújo IM; Nóbrega C; et al. "How can we modulate aging through nutrition and physical exercise? An epigenetic approach.". Aging (2023): http://europepmc.org/abstract/med/37086262.
    10.18632/aging.204668
  16. Writing Committee for the REMAP-CAP Investigators; Higgins AM; Berry LR; Lorenzi E; Murthy S; McQuilten Z; Mouncey PR; et al. "Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.". JAMA (2023): http://europepmc.org/abstract/med/36525245.
    10.1001/jama.2022.23257
  17. Casalino S; Frangione E; Chung M; MacDonald G; Chowdhary S; Mighton C; Faghfoury H; et al. "Genome screening, reporting, and genetic counseling for healthy populations.". Human genetics (2022): http://europepmc.org/abstract/med/36331656.
    10.1007/s00439-022-02480-7
  18. Tsang JLY; Binnie A; Duan EH; Johnstone J; Heels-Ansdell D; Reeve B; Trop S; et al. "Academic and Community ICUs Participating in a Critical Care Randomized Trial: A Comparison of Patient Characteristics and Trial Metrics.". Critical care explorations (2022): http://europepmc.org/abstract/med/36419633.
    10.1097/cce.0000000000000794
  19. Burns KEA; Moss M; Lorens E; Jose EKA; Martin CM; Viglianti EM; Fox-Robichaud A; et al. "Wellness and Coping of Physicians Who Worked in ICUs During the Pandemic: A Multicenter Cross-Sectional North American Survey.". Critical care medicine (2022): http://europepmc.org/abstract/med/36300945.
    10.1097/ccm.0000000000005674
  20. Conway Morris A; Kohler K; De Corte T; Ercole A; De Grooth HJ; Elbers PWG; Povoa P; et al. "Co-infection and ICU-acquired infection in COIVD-19 ICU patients: a secondary analysis of the UNITE-COVID data set.". Critical care (London, England) (2022): http://europepmc.org/abstract/med/35922860.
    10.1186/s13054-022-04108-8
  21. Greco M; De Corte T; Ercole A; Antonelli M; Azoulay E; Citerio G; Morris AC; et al. "Correction to: Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave: the global UNITE-COVID study.". Intensive care medicine (2022): http://europepmc.org/abstract/med/35796813.
    10.1007/s00134-022-06801-2
  22. Conway Morris A; Kohler K; De Corte T; Ercole A; De Grooth HJ; Elbers PWG; Povoa P; et al. "Correction: Co-infection and ICU-acquired infection in COVID-19 ICU patients: a secondary analysis of the UNITE-COVID data set.". Critical care (London, England) (2022): http://europepmc.org/abstract/med/35978317.
    10.1186/s13054-022-04124-8
  23. Greco M; De Corte T; Ercole A; Antonelli M; Azoulay E; Citerio G; Morris AC; et al. "Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave: the global UNITE-COVID study.". Intensive care medicine (2022): http://europepmc.org/abstract/med/35596752.
    10.1007/s00134-022-06705-1
  24. Mestre A; Muster M; El Adib AR; Ösp Egilsdottir H; Byermoen KR; Padilha M; Aguilar T; et al. "The impact of small-group virtual patient simulator training on perceptions of individual learning process and curricular integration: a multicentre cohort study of nursing and medical students.". BMC medical education (2022): http://europepmc.org/abstract/med/35578233.
    10.1186/s12909-022-03426-3
  25. WHO Solidarity Trial Consortium. "Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses.". Lancet (London, England) (2022): http://europepmc.org/abstract/med/35512728.
    10.1016/s0140-6736(22)00519-0
  26. Mourão Carvalho N; Martins C; Cartaxo V; Marreiros A; Justo E; Raposo C; Binnie A. "Out-of-hospital cardiac arrest in the Algarve region of Portugal: a retrospective registry trial with outcome data.". European journal of emergency medicine : official journal of the European Society for Emergency Medicine (2022): http://europepmc.org/abstract/med/34775452.
    10.1097/mej.0000000000000885
  27. Tsang JLY; Fowler R; Cook DJ; Burns KEA; Hunter K; Forcina V; Hwang A; et al. "Motivating factors, barriers and facilitators of participation in COVID-19 clinical research: A cross-sectional survey of Canadian community intensive care units.". PloS one (2022): http://europepmc.org/abstract/med/35476678.
    10.1371/journal.pone.0266770
  28. REMAP-CAP Writing Committee for the REMAP-CAP Investigators; Bradbury CA; Lawler PR; Stanworth SJ; McVerry BJ; McQuilten Z; Higgins AM; Mouncey PR; Gordon AC. "Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.". JAMA (2022): http://europepmc.org/abstract/med/35315874.
    10.1001/jama.2022.2910
  29. Ali K; Azher T; Baqi M; Binnie A; Borgia S; Carrier FM; Cavayas YA; et al. "Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial.". CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne (2022): http://europepmc.org/abstract/med/35045989.
    10.1503/cmaj.211698
  30. Lau VI; Binnie A; Basmaji J; Baig N; Opgenorth D; Cameron S; O'Hearn K; et al. "Needs Assessment Survey Identifying Research Processes Which may be Improved by Automation or Artificial Intelligence: ICU Community Modeling and Artificial Intelligence to Improve Efficiency (ICU-Comma).". Journal of intensive care medicine (2021): http://europepmc.org/abstract/med/34898324.
    10.1177/08850666211064844
  31. Tsang JLY; Fowler R; Cook DJ; Ma H; Binnie A. "How can we increase participation in pandemic research in Canada?". Canadian journal of anaesthesia = Journal canadien d'anesthesie (2021): http://europepmc.org/abstract/med/34642867.
    10.1007/s12630-021-02119-7
  32. Sholzberg M; Tang GH; Rahhal H; AlHamzah M; Kreuziger LB; Áinle FN; Alomran F; et al. "Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial.". BMJ (Clinical research ed.) (2021): http://europepmc.org/abstract/med/34649864.
    10.1136/bmj.n2400
  33. Writing Committee for the REMAP-CAP Investigators; Estcourt LJ; Turgeon AF; McQuilten ZK; McVerry BJ; Al-Beidh F; Annane D; et al. "Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.". JAMA (2021): http://europepmc.org/abstract/med/34606578.
    10.1001/jama.2021.18178
  34. Johnstone J; Meade M; Lauzier F; Marshall J; Duan E; Dionne J; Arabi YM; et al. "Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial.". JAMA (2021): http://europepmc.org/abstract/med/34546300.
    10.1001/jama.2021.13355
  35. Taher J; Mighton C; Chowdhary S; Casalino S; Frangione E; Arnoldo S; Bearss E; et al. "Implementation of serological and molecular tools to inform COVID-19 patient management: protocol for the GENCOV prospective cohort study.". BMJ open (2021): http://europepmc.org/abstract/med/34593505.
    10.1136/bmjopen-2021-052842
  36. Alexandra Binnie; Kyra Moura; Claire Moura; Frédérick D’Aragon; Jennifer L. Y. Tsang. "Psychosocial distress amongst Canadian intensive care unit healthcare workers during the acceleration phase of the COVID-19 pandemic". PLOS ONE (2021): https://doi.org/10.1371/journal.pone.0254708.
    10.1371/journal.pone.0254708
  37. ATTACC Investigators; ACTIV-4a Investigators; REMAP-CAP Investigators; Lawler PR; Goligher EC; Berger JS; Neal MD; et al. "Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.". The New England journal of medicine (2021): http://europepmc.org/abstract/med/34351721.
    10.1056/nejmoa2105911
  38. REMAP-CAP Investigators; ACTIV-4a Investigators; ATTACC Investigators; Goligher EC; Bradbury CA; McVerry BJ; Lawler PR; et al. "Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19.". The New England journal of medicine (2021): http://europepmc.org/abstract/med/34351722.
    10.1056/nejmoa2103417
  39. Arabi YM; Gordon AC; Derde LPG; Nichol AD; Murthy S; Beidh FA; Annane D; et al. "Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial.". Intensive care medicine (2021): http://europepmc.org/abstract/med/34251506.
    10.1007/s00134-021-06448-5
  40. Alexandra Binnie; Emanuel Fernandes; Helder Almeida-Lousada; Ramon Andrade de Mello; Pedro Castelo-Branco. "CRISPR-based strategies in infectious disease diagnosis and therapy". Infection (2021): https://doi.org/10.1007/s15010-020-01554-w.
    10.1007/s15010-020-01554-w
  41. Jennifer L. Y. Tsang; Alexandra Binnie; Robert A. Fowler. "Twenty articles that critical care clinicians should read about COVID-19". Intensive Care Medicine 47 3 (2021): 337-341. https://doi.org/10.1007/s00134-020-06329-3.
    10.1007/s00134-020-06329-3
  42. Salluh JIF; Arabi YM; Binnie A. "COVID-19 research in critical care: the good, the bad, and the ugly.". Intensive care medicine (2021): http://europepmc.org/abstract/med/33646318.
    10.1007/s00134-021-06367-5
  43. WHO Solidarity Trial Consortium; Pan, Hongchao; Peto, Richard; Henao-Restrepo, Ana-Maria; Preziosi, Marie-Pierre; Sathiyamoorthy, Vasee; Abdool Karim, Quarraisha; et al. "Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.". New England Journal of Medicine 384 (2021): 497-511. https://europepmc.org/articles/PMC7727327.
    Open access • 10.1056/nejmoa2023184
  44. REMAP-CAP Investigators; Gordon AC; Mouncey PR; Al-Beidh F; Rowan KM; Nichol AD; Arabi YM; et al. "Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19.". The New England journal of medicine (2021): http://europepmc.org/abstract/med/33631065.
    10.1056/nejmoa2100433
  45. Arabi YM; Azoulay E; Al-Dorzi HM; Phua J; Salluh J; Binnie A; Hodgson C; et al. "How the COVID-19 pandemic will change the future of critical care.". Intensive care medicine (2021): http://europepmc.org/abstract/med/33616696.
    10.1007/s00134-021-06352-y
  46. Angus, Derek C; Derde, Lennie; Al-Beidh, Farah; Annane, Djillali; Arabi, Yaseen; Beane, Abigail; Van Bentum-Puijk, Wilma; et al. "Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.". JAMA (2020): https://europepmc.org/articles/PMC7489418.
    Open access • 10.17863/cam.60052
  47. "Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.". JAMA (2020): https://europepmc.org/articles/PMC7489418.
    10.1001/jama.2020.17022
  48. Lau VI; Cook DJ; Fowler R; Rochwerg B; Johnstone J; Lauzier F; Marshall JC; et al. "Economic evaluation alongside the Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial (E-PROSPECT): study protocol.". BMJ open (2020): http://europepmc.org/abstract/med/32595159.
    10.1136/bmjopen-2019-036047
  49. Jennifer L Y Tsang; Alexandra Binnie; George Farjou; Dimitra Fleming; Maham Khalid; Erick Duan. "Participation of more community hospitals in randomized trials of treatments for COVID-19 is needed.". Canadian Medical Association Journal 192 (2020): E555-E555. https://europepmc.org/articles/PMC7241878.
    Open access • 10.1503/cmaj.75585
  50. Binnie A; Tsang JLY; Hu P; Carrasqueiro G; Castelo-Branco P; Dos Santos CC. "Epigenetics of Sepsis.". Critical care medicine (2020): http://europepmc.org/abstract/med/32167492.
    10.1097/ccm.0000000000004247
  51. Binnie, A.; Walsh, C.J.; Hu, P.; Dwivedi, D.J.; Fox-Robichaud, A.; Liaw, P.C.; Tsang, J.L.Y.; et al. "Epigenetic Profiling in Severe Sepsis: A Pilot Study of DNA Methylation Profiles in Critical Illness". Critical care medicine 48 2 (2020): 142-150. http://www.scopus.com/inward/record.url?eid=2-s2.0-85077872940&partnerID=MN8TOARS.
    10.1097/CCM.0000000000004097
  52. Binnie, Alexandra. "Epigenetic Profiling in Severe Sepsis: A Pilot Study of DNA Methylation Profiles in Critical Illness.". Critical care medicine (2019): https://doi.org/10.1097/CCM.0000000000004097.
    10.1097/ccm.0000000000004097
  53. Binnie, Alexandra. "Fostering community hospital research.". CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne (2019): https://doi.org/10.1503/cmaj.190055.
    10.1503/cmaj.190055
  54. Binnie A; Lage J; Dos Santos C. "How can biomarkers be used to differentiate between infection and non-infectious causes of inflammation?". Evidence-Based Practice of Critical Care (2019): http://europepmc.org/abstract/PMC/PMC7152028.
  55. Binnie, Alexandra. "Roadmap of DNA methylation in breast cancer identifies novel prognostic biomarkers.". BMC cancer (2019): http://europepmc.org/articles/PMC6416975.
    10.1186/s12885-019-5403-0
  56. Binnie, Alexandra. "Epigenetic therapy in urologic cancers: an update on clinical trials.". Oncotarget (2017): http://europepmc.org/abstract/med/28036257.
    10.18632/oncotarget.14226
  57. Binnie, Alexandra. "Biomarkers in acute respiratory distress syndrome.". Current opinion in critical care (2014): http://europepmc.org/abstract/med/24296379.
    10.1097/mcc.0000000000000048
  58. Binnie, A.; Tsang, J.L.Y.; Dos Santos, C.C.. "Biomarkers in acute respiratory distress syndrome". Current Opinion in Critical Care 20 1 (2014): 47-55. http://www.scopus.com/inward/record.url?eid=2-s2.0-84895069834&partnerID=MN8TOARS.
    10.1097/MCC.0000000000000048
  59. Binnie, Alexandra. "Homologous gene sequences mediate transcription-domain formation.". Journal of cell science (2006): http://europepmc.org/abstract/med/16940354.
    10.1242/jcs.03050
  60. Binnie, Alexandra. "Promoter proximal splice sites enhance transcription.". Genes & development (2002): http://europepmc.org/abstract/med/12414732.
    10.1101/gad.983602
  61. Binnie, Alexandra. "Gamma-irradiation directly affects the formation of coding joints in SCID cell lines.". Journal of immunology (Baltimore, Md. : 1950) (1999): http://europepmc.org/abstract/med/10553067.
  62. Binnie, A.; Olson, S.; Wu, G.E.; Lewis, S.M.. "Gamma-irradiation directly affects the formation of coding joints in SCID cell lines". Journal of Immunology 163 10 (1999): 5418-5426. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033571736&partnerID=MN8TOARS.
Preprint
  1. Hays LMC; Black M; Prunty MP; Murthy S; van de Veerdonk FL; Annane D; Binnie A; et al. "Could treatment with immunomodulatory agents targeting IL-1, IL-6, or JAK signalling improve outcomes in patients with severe influenza pneumonia? A systematic and narrative review". 2022. http://europepmc.org/abstract/PPR/PPR576477.
    10.12688/hrbopenres.13613.1