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Identificação

Identificação pessoal

Nome completo
Aurea Lima

Nomes de citação

  • Lima, Aurea

Identificadores de autor

Ciência ID
A212-12E7-7E9E
ORCID iD
0000-0002-9779-0584

Telefones

Telemóvel
  • (+352) 919904845 (Pessoal)

Moradas

  • Rua Luís de Camões, n. 255, 4520-605, São João de Ver, Santa Maria da Feira, Portugal (Pessoal)

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês
Formação
Grau Classificação
2018
Concluído
 Pós-graduação em Medicina Estética (Pós-Graduação)
Hospital-Escola da Universidade Fernando Pessoa, Portugal
2016
Concluído
 Medicina (Mestrado integrado)
Especialização em Sem especialização
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Moving Towards Personalized Medicine in Rheumatoid Arthritis - Methotrexate Intracellular Pathways and Phase II Reactions as Pharmacogenetic Predictors of Methotrexate Therapeutic Outcome" (TESE/DISSERTAÇÃO)
2011
Concluído
 Ciências Médicas (Doutoramento)
Especialização em Sem especialidade
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Methotrexate pharmacogenomics and predictors of therapeutic outcome in rheumatoid arthritis" (TESE/DISSERTAÇÃO)
2007
Concluído
 Mestrado em Medicina e Oncologia Molecular (Mestrado)
Universidade do Porto Faculdade de Medicina, Portugal
 2007
2004
Concluído
 Licenciatura em Ciências Farmacêuticas (Licenciatura)
Instituto Universitário de Ciências da Saúde, Portugal
 17 valores
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2019 - Atual Professor Associado Convidado (Docente Universitário) Instituto Universitário de Ciências da Saúde, Portugal
2014 - 2019 Professor Auxiliar (Docente Universitário) Instituto Universitário de Ciências da Saúde, Portugal
2013 - 2014 Assistente (Docente Universitário) Instituto Universitário de Ciências da Saúde, Portugal

Outras Carreiras

Categoria Profissional
Instituição de acolhimento 		Empregador
2024/01/08 - Atual Assistente (Médica) Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
2018/01/01 - 2023/10/11 Interno (Médica) Centro Hospitalar de Entre o Douro e Vouga EPE, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2014 - 2016 Conselho científico/técnico-científico ou orgão correspondente Instituto Universitário de Ciências da Saúde, Portugal
2013 - 2016 Conselho pedagógico Instituto Universitário de Ciências da Saúde, Portugal
Projetos

Projeto

Designação Financiadores
2010/03/01 - 2014/02/28 ROLE OF HUMAN POLYMORPHISMS IN RHEUMATOID ARTHRITIS PATIENTS TREATED WITH METHOTREXATE AS POTENTIAL PREDICTORS OF TOXIC EFFECTS AND THERAPEUTIC OUTCOME
SFRH/BD/64441/2009
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. Tiago Gomes de Oliveira; Áurea Lima. "The role of onco-aesthetic in breast cancer: a clinical report study". Aesthetic Medicine (2023): https://doi.org/10.57662/am.v9i3.15191.
    10.57662/am.v9i3.15191
  2. Áurea Lima; Hugo Sousa; Rui Medeiros; Amanda Nobre; Manuela Machado. "PD-L1 expression in EBV associated gastric cancer: a systematic review and meta-analysis". Discover Oncology 13 1 (2022): https://doi.org/10.1007/s12672-022-00479-0.
    10.1007/s12672-022-00479-0
  3. Aurea Lima; Hugo Sousa; Amanda Nobre; Ana Luisa Faria; Manuela Machado. "The Impact of COVID-19 Pandemic in Portuguese Cancer Patients: A Retrospective Study". International Journal of Environmental Research and Public Health (2021): https://doi.org/10.3390/ijerph18168552.
    10.3390/ijerph18168552
  4. Áurea Lima; Isa Peixoto; Susana Sarandão; Daniel Melo; Ângelo Rodrigues; Helena Pereira; Katsuhiro Tanaka. "Breast Cancer Metastasis in a Renal Carcinoma Pulmonary Metastasis: A Rare Example of Tumor-to-Tumor Metastasis". Case Reports in Oncological Medicine 2021 (2021): 1-6. https://doi.org/10.1155/2021/3054232.
    10.1155/2021/3054232
  5. "Chylothorax: An Unsuspected Presentation of Lymphoproliferative Disease". Archives of Clinical and Medical Case Reports 05 02 (2021): http://dx.doi.org/10.26502/acmcr.96550350.
    10.26502/acmcr.96550350
  6. "What we Really (don’t) Know about Immunotherapy: A Clinical Case of Urothelial Carcinoma". Annals of Case Reports (2020): http://dx.doi.org/10.29011/2574-7754.100529.
    10.29011/2574-7754.100529
  7. "Replication study of polymorphisms associated with response to methotrexate in patients with rheumatoid arthritis". Scientific Reports 8 1 (2018): http://dx.doi.org/10.1038/s41598-018-25634-y.
    10.1038/s41598-018-25634-y
  8. "Evaluation of a clinical pharmacogenetics model to predict methotrexate response in patients with rheumatoid arthritis". The Pharmacogenomics Journal 18 4 (2018): 539-545. http://dx.doi.org/10.1038/s41397-018-0017-5.
    10.1038/s41397-018-0017-5
  9. "Liquid chromatographic methods for the therapeutic drug monitoring of methotrexate as clinical decision support for personalized medicine: A brief review". Biomedical Chromatography 32 5 (2018): e4159-e4159. http://dx.doi.org/10.1002/bmc.4159.
    10.1002/bmc.4159
  10. "Moving toward personalized medicine in rheumatoid arthritis: SNPs in methotrexate intracellular pathways are associated with methotrexate therapeutic outcome.". Pharmacogenomics (2016): https://doi.org/10.2217/pgs-2016-0067.
    10.2217/pgs-2016-0067
  11. "Genetic Polymorphisms Associated to Folate Transport as Predictors of Increased Risk for Acute Lymphoblastic Leukemia in Mexican Children". Frontiers in Pharmacology 7 (2016): http://dx.doi.org/10.3389/fphar.2016.00238.
    10.3389/fphar.2016.00238
  12. Azevedo R; Ferreira JA; Peixoto A; Neves M; Sousa N; Lima A; Santos LL. "Emerging antibody-based therapeutic strategies for bladder cancer: A systematic review.". (2015): http://europepmc.org/abstract/med/26196222.
    10.1016/j.jconrel.2015.07.002
  13. Azevedo R; Bernardes M; Fonseca J; Lima A. "Smartphone application for rheumatoid arthritis self-management: cross-sectional study revealed the usefulness, willingness to use and patients' needs.". (2015): http://europepmc.org/abstract/med/25903352.
    10.1007/s00296-015-3270-9
  14. Lima A; Bernardes M; Azevedo R; Medeiros R; Seabra V. "Pharmacogenomics of Methotrexate Membrane Transport Pathway: Can Clinical Response to Methotrexate in Rheumatoid Arthritis Be Predicted?". (2015): http://europepmc.org/abstract/med/26086825.
    10.3390/ijms160613760
  15. Romão VC; Lima A; Bernardes M; Canhão H; Fonseca JE. "Three decades of low-dose methotrexate in rheumatoid arthritis: can we predict toxicity?". (2014): http://europepmc.org/abstract/med/25391609.
    10.1007/s12026-014-8564-6
  16. Lima A; Sousa H; Monteiro J; Azevedo R; Medeiros R; Seabra V. "Genetic polymorphisms in low-dose methotrexate transporters: current relevance as methotrexate therapeutic outcome biomarkers.". (2014): http://europepmc.org/abstract/med/25340735.
    10.2217/pgs.14.116
  17. Lima A; Bernardes M; Azevedo R; Monteiro J; Sousa H; Medeiros R; Seabra V. "SLC19A1, SLC46A1 and SLCO1B1 Polymorphisms As Predictors Of Methotrexate-Related Toxicity In Portuguese Rheumatoid Arthritis Patients.". (2014): http://europepmc.org/abstract/med/25124723.
    10.1093/toxsci/kfu162
  18. Lima A; Seabra V; Martins S; Coelho A; Araújo A; Medeiros R. "Thymidylate synthase polymorphisms are associated to therapeutic outcome of advanced non-small cell lung cancer patients treated with platinum-based chemotherapy.". (2014): http://europepmc.org/abstract/med/24554028.
  19. Azevedo, A.R.P.; de Sousa, H.M.L.; Monteiro, J.A.F.; Lima, A.R.N.P.. "Future perspectives of Smartphone applications for rheumatic diseases self-management". Rheumatology International (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84906529442&partnerID=MN8TOARS.
    10.1007/s00296-014-3117-9
  20. Lima, A.; Monteiro, J.; Bernardes, M.; Sousa, H.; Azevedo, R.; Seabra, V.; Medeiros, R.. "Prediction of methotrexate clinical response in Portuguese rheumatoid arthritis patients: Implication of MTHFR RS1801133 and ATIC RS4673993 polymorphisms". BioMed Research International 2014 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84902174947&partnerID=MN8TOARS.
    10.1155/2014/368681
  21. Lima, A.; Bernardes, M.; Sousa, H.; Azevedo, R.; Costa, L.; Ventura, F.; Seabra, V.; Medeiros, R.. "SLC19A1 80G allele as a biomarker of methotrexate-related gastrointestinal toxicity in Portuguese rheumatoid arthritis patients". Pharmacogenomics 15 6 (2014): 807-820. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896373858&partnerID=MN8TOARS.
    10.2217/PGS.13.244
  22. Lima A; Seabra V; Bernardes M; Azevedo R; Sousa H; Medeiros R. "Role of Key TYMS Polymorphisms on Methotrexate Therapeutic Outcome in Portuguese Rheumatoid Arthritis Patients.". (2014): http://europepmc.org/abstract/med/25279663.
    10.1371/journal.pone.0108165
  23. Lima, A.; Azevedo, R.; Sousa, H.; Seabra, V.; Medeiros, R.. "Current approaches for TYMS polymorphisms and their importance in molecular epidemiology and pharmacogenetics". Pharmacogenomics 14 11 (2013): 1337-1351. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882241312&partnerID=MN8TOARS.
    10.2217/pgs.13.118
Tese / Dissertação
  1. Silva, Mónica Francisco. "ADVANCING PERSONALIZED MEDICINE IN METHOTREXATE-TREATED DISEASES: HPLC-DAD METHOD DEVELOPMENT FOR THERAPEUTIC DRUG MONITORING". Mestrado, 2017. http://hdl.handle.net/10316/81430.
  2. Áurea Rosa Nunes Pereira Lima. "Moving Towards Personalized Medicine in Rheumatoid Arthritis - Methotrexate Intracellular Pathways and Phase II Reactions as Pharmacogenetic Predictors of Methotrexate Therapeutic Outcome". Mestrado, 2016. https://repositorio-aberto.up.pt/handle/10216/87890.
  3. Áurea Rosa Nunes Pereira Lima. "Methotrexate pharmacogenomics and predictors of therapeutic outcome in rheumatoid arthritis". Doutoramento, 2014. https://repositorio-aberto.up.pt/handle/10216/84679.