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Carlos Palmeira, is Full Professor in the Department of Life Sciences, University of Coimbra, Portugal and PI at Center for Neurosciences and Cell Biology, from the same University. His research interests are focused on the pathophysiological mechanisms of mitochondrial dysfunction and human health, with particular expertise in the study of the role of mitochondrial dysfunction in the pathogenesis of hepatic diseases and ischemia/reperfusion. He is a member of several national/international societies, and serves as Associate Editor in the journals Toxicology and Applied Pharmacology and Toxicology Mechanisms and Methods, being member of the Editorial Board in several other journals. He is author/co-author of more than 120 papers. He received his Ph.D in Biochemistry at the University of Coimbra, Portugal and postdoctoral training in biochemical toxicology at the University of Minnesota, Duluth, USA.
Identificação

Identificação pessoal

Nome completo
Carlos Palmeira

Nomes de citação

  • Palmeira, Carlos
  • Palmeira, Carlos M.

Identificadores de autor

Ciência ID
9C17-78E6-DA25
ORCID iD
0000-0002-2639-7697

Telefones

Telefone
  • (+351) 239240700 (Profissional)

Moradas

  • DEPARTAMENTO DE CIÊNCIAS DA VIDA, Universidade de Coimbra, Colégio de S. Bento, Calçada Martim de Freitas, 3000-456, Coimbra, Coimbra, Portugal (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica
  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Médicas e da Saúde - Medicina Básica - Toxicologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Francês Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2010/02
Concluído
Biociências (Título de Agregado)
Especialização em Biologia Celular e Molecular
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
1995/01/13
Concluído
Bioquímica (Doutoramento)
Especialização em Toxicologia Bioquímica
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Alterações Metabólicas em Células Hepáticas de Rato Induzidas por Herbicidas de Uso Generalizado " (TESE/DISSERTAÇÃO)
1989/09
Concluído
Biologia (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Percurso profissional

Ciência

1997 - Atual Investigador (Investigação)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
1995/02/01 - 1997/03/31 Pós-doutorado (Investigação)
Fundação para a Ciência e a Tecnologia, Portugal

Docência no Ensino Superior

2012/09/03 - Atual Professor Catedrático (Docente Universitário)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006/03/01 - 2012/09/03 Professor Associado (Docente Universitário)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
1997/04/01 - 2006/03/01 Professor Auxiliar (Docente Universitário)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Outros

2010/11 - 2012/11 Diretor do Departamento de Ciências da Vida
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2009 Diretor do Departamento de Zoologia
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2002 - 2004 Diretor do Departamento de Zoologia
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2000 - 2002 Diretor do Departamento de Zoologia
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Projetos

Projeto

Designação Financiadores
2018 - Atual FRUITIFY - Use of blueberry juice as a nutraceutical strategy targeting gut dysbiosis to prevent the progression from prediabetes to diabetes
PTDC/SAU-NUT/31712/2017 | POCI-01-0145-FEDER-031712
Investigador
Universidade de Coimbra Faculdade de Medicina, Portugal
2016 - 2019/12 A INTERAÇÃO ENTRE cAMP E SIRTUÍNAS COMO UM MECANISMO DE CONTROLO MITOCONDRIAL E METABÓLICO
PTDC /BIM-MEC / 6911 / 2014
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Secretaria de Estado de Ciência Tecnologia e Ensino Superior
2016 - 2019 EXERCITANDO O FUTURO: Exercício voluntário durante diabetes gestacional com uma estratégia para melhorar a função mitocondrial na descendência.
PTDC /DTP-DES / 1082 / 2014
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013 - 2014/02 Chronic effects of silver nanoparticles (AgNPs) on rat liver, kidney and heart mitochondrial function
FA8655-13-1-3036
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
EOARD
2010 - 2013 ALTERAÇÕES NAS VIAS FISIOLÓGICAS E MECANISMOS MOLECULARES REGULADORES DA HOMEOSTASE ENERGÉTICA NA OBESIDADE E SÍNDROME METABÓLICO: IDENTIFICAÇÃO DE NOVAS ESTRATÉGIAS E ALVOS TERAPÊUTICOS
PTDC /SAU-NEU / 102612 / 2008
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2011 - 2012/08 ABILITY OF A MITOCHONDRIAL IMPROVER, BERBERINE, TO ATTENUATE PARKINSON´S DISEASE
RRIA 2011
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Michael J Fox Foundation for Parkinson's Research
2010 - 2012/08 BENEFÍCIOS DO CONTROLO METABÓLICO PRECOCE: PREVENÇÃO DA FORMAÇÃO DE MEMÓRIA HIPERGLICÉMICA ATRAVÉS DA ESTIMULAÇÃO DA BIOENERGÉTICA.
PTDC /QUI-BIQ / 103514 / 2008
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
2007 - 2010/12 ALTERAÇÕES NAS VIAS FISIOLÓGICAS E MECANISMOS MOLECULARES REGULADORES DA HOMEOSTASE ENERGÉTICA NA OBESIDADE E SÍNDROME METABÓLICO: IDENTIFICAÇÃO DE NOVAS ESTRATÉGIAS E ALVOS TERAPÊUTICOS.
PTDC /SAU-OSM / 72443 / 2006
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
2008 - 2010/01 MODULAÇÃO DAS VIAS METABÓLICAS ENVOLVIDAS NO STRESS OXIDATIVO MITOCONDRIAL EM CONDIÇÕES DE HIPERGLICÉMIA: SUA RELEVÂNCIA NA PREVENÇÃO DA DIABETES
PTDC /QUI / 72826 / 2006
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
2007 - 2008/07 IN VITRO ASSESSMENT OF SILVER NANOPARTICLES TOXICITY IN HEPATIC MITOCHONDRIAL FUNCTION
FA8655-07-1-3047
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
EOARD
2002 - 2005/07 COLESTASE E ESTEATOSE HEPÁTICA: TERAPIA COM ÁCIDOS BILIARES. MECANISMOS CELULARES COM RELEVÂNCIA NA FUNÇÃO MITOCONDRIAL.
POCTI /CBO / 42486 / 2001
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
2004 - 2004/11 13C NMR ISOTOPOMER ANALYSIS OF INTERMEDIARY METABOLISM IN A ADRIAMYCIN HEART FAILURE MODEL
1774-602-6050-7901
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
National Heart Lung and Blood Institute
2001 - 2002 FUNÇÃO MITOCONDRIAL NO CÉREBRO E CORAÇÃO DE RATOS MODELO DE DIABETES MELLITUS NÃO DEPENDENTE DE INSULINA (GOTO-KAKIZAKI)
SAPIENS 43642 / 99
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
1998 - 2000 ISQUEMIA MIOCÁRDICA: ACÇÃO DE FÁRMACOS. IMPORTÂNCIA DA FUNÇÃO MITOCONDRIAL
PRAXIS / PSAU / P / SAU / /6/96
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
1997 - 2000 ISQUEMIA E DIABETES: ESTUDO COMPARATIVO DAS ALTERAÇÕES METABÓLICAS EM RATOS GK (UM MODELO GENÉTICO DE DIABETES NÃO DEPENDENTE DE INSULINA E EM RATOS WISTAR (MODELO)
PRAXIS/PSAU/P/SAU/1 /96
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
1996 - 2000 RASTREIO EXPERIMENTAL DA BIOTOXICIDADE: TECNOLOGIAS IN VITRO ALTERNATIVAS AOS TESTES ANIMAIS.
PRAXIS /2 / 2.2/BIO / 1156 / 95
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
1992 - 1995 TOXICOLOGIA APLICADA DE PESTICIDAS: ALTERAÇÕES FUNCIONAIS DE HEPATÓCITOS E SEUS MITOCÔNDRIOS
PBIC /C / BIO / 1159 / 92
Bolseiro de Doutoramento
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Produções

Publicações

Artigo em revista
  1. Makrecka-Kuka, M.; Liepinsh, E.; Murray, A.J.; Lemieux, H.; Dambrova, M.; Tepp, K.; Puurand, M.; et al. "Altered mitochondrial metabolism in the insulin-resistant heart". Acta Physiologica 228 3 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85077842678&partnerID=MN8TOARS.
    10.1111/apha.13430
  2. Almeida, N.; Carrara, G.; Palmeira, C.M.; Fernandes, A.S.; Parsons, M.; Smith, G.L.; Saraiva, N.. "Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H2O2-Dependent Mechanism". Redox Biology 28 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85074222003&partnerID=MN8TOARS.
    10.1016/j.redox.2019.101361
  3. Gomes, P.; Viana, S.D.; Nunes, S.; Rolo, A.P.; Palmeira, C.M.; Reis, F.. "The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders". Ageing Research Reviews 57 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85076952156&partnerID=MN8TOARS.
    10.1016/j.arr.2019.100983
  4. Martins, Rui Miguel; Teodoro, João Soeiro; Furtado, Emanuel; Rolo, Anabela Pinto; Palmeira, Carlos Marques; Tralhão, José Guilherme. "Evaluation of bioenergetic and mitochondrial function in liver transplantation". Clinical and Molecular Hepatology 25 2 (2019): 190-198. http://dx.doi.org/10.3350/cmh.2018.0087.
    10.3350/cmh.2018.0087
  5. Carmo, M.; Gonçalves, F.Q.; Canas, P.M.; Oses, J.-P.; Fernandes, F.D.; Duarte, F.V.; Palmeira, C.M.; et al. "Enhanced ATP release and CD73-mediated adenosine formation sustain adenosine A2A receptor over-activation in a rat model of Parkinson's disease". British Journal of Pharmacology 176 18 (2019): 3666-3680. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070072977&partnerID=MN8TOARS.
    10.1111/bph.14771
  6. Alexandrino, H.; Palmeira, C.. "Correspondence". British Journal of Surgery 106 1 (2019): 152-152. http://www.scopus.com/inward/record.url?eid=2-s2.0-85058912518&partnerID=MN8TOARS.
    10.1002/bjs.11055
  7. Palmeira, C.M.; Teodoro, J.S.; Amorim, J.A.; Steegborn, C.; Sinclair, D.A.; Rolo, A.P.. "Mitohormesis and metabolic health: The interplay between ROS, cAMP and sirtuins". Free Radical Biology and Medicine 141 (2019): 483-491. http://www.scopus.com/inward/record.url?eid=2-s2.0-85069629808&partnerID=MN8TOARS.
    10.1016/j.freeradbiomed.2019.07.017
  8. Martins, R.M.; Teodoro, J.S.; Furtado, E.; Rolo, A.P.; Palmeira, C.M.; Tralhão, J.G.. "Evaluation of bioenergetic and mitochondrial function in liver transplantation". Clinical and Molecular Hepatology 25 2 (2019): 190-198. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068517981&partnerID=MN8TOARS.
    10.3350/cmh.2018.0087
  9. Martins, R.M.; Teodoro, J.S.; Furtado, E.; Oliveira, R.C.; Tralhão, J.G.; Rolo, A.P.; Palmeira, C.M.. "Mild hypothermia during the reperfusion phase protects mitochondrial bioenergetics against ischemia-reperfusion injury in an animal model of ex-vivo liver transplantation—An experimental study". International Journal of Medical Sciences 16 9 (2019): 1304-1312. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072941379&partnerID=MN8TOARS.
    10.7150/ijms.34617
  10. Machado, I.F.; Teodoro, J.S.; Palmeira, C.M.; Rolo, A.P.. "miR-378a: a new emerging microRNA in metabolism". Cellular and Molecular Life Sciences (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85075434955&partnerID=MN8TOARS.
    10.1007/s00018-019-03375-z
  11. Teodoro, J.S.; Nunes, S.; Rolo, A.P.; Reis, F.; Palmeira, C.M.. "Therapeutic options targeting oxidative stress, mitochondrial dysfunction and inflammation to hinder the progression of vascular complications of diabetes". Frontiers in Physiology 10 JAN (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85065463466&partnerID=MN8TOARS.
    10.3389/fphys.2018.01857
  12. Adlbrecht, C.; Blanco-Verea, A.; Bouzas-Mosquera, M.C.; Brion, M.; Burtscher, M.; Carbone, F.; Chang, T.-T.; et al. "Research update for articles published in EJCI in 2016". European Journal of Clinical Investigation 48 10 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85053529293&partnerID=MN8TOARS.
    10.1111/eci.13016
  13. Pereira, L.C.; Cabral Miranda, L.F.; Franco-Bernardes, M.F.; Tasso, M.J.; Duarte, F.V.; Inácio Varela, A.T.; Rolo, A.P.; Marques Palmeira, C.M.; Dorta, D.J.. "Mitochondrial damage and apoptosis: Key features in BDE-153-induced hepatotoxicity". Chemico-Biological Interactions 291 (2018): 192-201. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049064624&partnerID=MN8TOARS.
    10.1016/j.cbi.2018.06.021
  14. Martins, R.M.; Teodoro, J.S.; Furtado, E.; Rolo, A.P.; Palmeira, C.M.; Tralhão, J.G.. "Recent insights into mitochondrial targeting strategies in liver transplantation". International Journal of Medical Sciences 15 3 (2018): 248-256. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045188539&partnerID=MN8TOARS.
    10.7150/ijms.22891
  15. Panisello-Roselló, A.; Verde, E.; Lopez, A.; Flores, M.; Folch-Puy, E.; Rolo, A.; Palmeira, C.; et al. "Cytoprotective mechanisms in fatty liver preservation against cold ischemia injury: A comparison between IGL-1 and HTK". International Journal of Molecular Sciences 19 2 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85041019515&partnerID=MN8TOARS.
    10.3390/ijms19020348
  16. Egea, J.; Fabregat, I.; Frapart, Y.M.; Ghezzi, P.; Görlach, A.; Kietzmann, T.; Kubaichuk, K.; et al. "Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” (Redox Biol. (2017) 13 (94–162)(S2213231717303373)(10.1016/j.redox.2017.05.007))". Redox Biology 14 (2018): 694-696. http://www.scopus.com/inward/record.url?eid=2-s2.0-85032289195&partnerID=MN8TOARS.
    10.1016/j.redox.2017.10.001
  17. Martins, R.M.; Rolo, A.P.; Teodoro, J.S.; Furtado, E.; Oliveira, R.C.; Tralhão, J.G.; Palmeira, C.M.. "Addition of berberine to preservation solution in an animal model of ex vivo liver transplant preserves mitochondrial function and bioenergetics from the damage induced by ischemia/reperfusion". International Journal of Molecular Sciences 19 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040938454&partnerID=MN8TOARS.
    10.3390/ijms19010284
  18. Teodoro, J.S.; Varela, A.T.; Duarte, F.V.; Gomes, A.P.; Palmeira, C.M.; Rolo, A.P.. "Indirubin and NAD+ prevent mitochondrial ischaemia/reperfusion damage in fatty livers". European Journal of Clinical Investigation 48 6 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85045238716&partnerID=MN8TOARS.
    10.1111/eci.12932
  19. Panisello-Roselló, A.; Lopez, A.; Folch-Puy, E.; Carbonell, T.; Rolo, A.; Palmeira, C.; Adam, R.; Net, M.; Roselló-Catafau, J.. "Role of aldehyde dehydrogenase 2 in ischemia reperfusion injury: An update". World Journal of Gastroenterology 24 27 (2018): 2984-2994. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050972436&partnerID=MN8TOARS.
    10.3748/wjg.v24.i27.2984
  20. Panisello-Roselló, A.; Alva, N.; Flores, M.; Lopez, A.; Benítez, C.C.; Folch-Puy, E.; Rolo, A.; et al. "Aldehyde dehydrogenase 2 (ALDH2) in rat fatty liver cold ischemia injury". International Journal of Molecular Sciences 19 9 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85052507134&partnerID=MN8TOARS.
    10.3390/ijms19092479
  21. Pereira LC; Duarte FV; Varela ATIF; Rolo AP; Palmeira CMM; Dorta DJ. "Exposure to BDE-153 induces autophagy in HepG2 cells.". (2017): http://europepmc.org/abstract/med/28396260.
    10.1016/j.tiv.2017.04.005
  22. Zaouali MA; Panisello A; Lopez A; Castro C; Folch E; Carbonell T; Rolo A; et al. "GSK3ß and VDAC Involvement in ER Stress and Apoptosis Modulation during Orthotopic Liver Transplantation.". (2017): http://europepmc.org/abstract/med/28282906.
    10.3390/ijms18030591
  23. Pereira LC; Duarte FV; Varela AT; Rolo AP; Palmeira CM; Dorta DJ. "An autophagic process is activated in HepG2 cells to mediate BDE-100-induced toxicity.". (2017): http://europepmc.org/abstract/med/27234317.
    10.1016/j.tox.2016.05.022
  24. Rossetti, A.; Togliatto, G.; Rolo, A.P.; Teodoro, J.S.; Granata, R.; Ghigo, E.; Columbano, A.; Palmeira, C.M.; Brizzi, M.F.. "Unacylated ghrelin prevents mitochondrial dysfunction in a model of ischemia/reperfusion liver injury". Cell Death Discovery 3 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85051289736&partnerID=MN8TOARS.
    10.1038/cddiscovery.2017.77
  25. Amorim, J.A.; Canas, P.M.; Tomé, A.R.; Rolo, A.P.; Agostinho, P.; Palmeira, C.M.; Cunha, R.A.. "Mitochondria in Excitatory and Inhibitory Synapses have Similar Susceptibility to Amyloid-ß Peptides Modeling Alzheimer's Disease". Journal of Alzheimer's Disease 60 2 (2017): 525-536. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029613373&partnerID=MN8TOARS.
    10.3233/JAD-170356
  26. Alexandrino, H.; Rolo, A.; Teodoro, J.S.; Donato, H.; Martins, R.; Serôdio, M.; Martins, M.; et al. "Bioenergetic adaptations of the human liver in the ALPPS procedure – how liver regeneration correlates with mitochondrial energy status". HPB 19 12 (2017): 1091-1103. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029605721&partnerID=MN8TOARS.
    10.1016/j.hpb.2017.08.005
  27. Egea, J.; Fabregat, I.; Frapart, Y.M.; Ghezzi, P.; Görlach, A.; Kietzmann, T.; Kubaichuk, K.; et al. "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)". Redox Biology 13 (2017): 94-162. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020032301&partnerID=MN8TOARS.
    10.1016/j.redox.2017.05.007
  28. Milton-Laskibar, I.; Aguirre, L.; Fernández-Quintela, A.; Rolo, A.P.; Teodoro, J.S.; Palmeira, C.M.; Portillo, M.P.. "Lack of additive effects of resveratrol and energy restriction in the treatment of hepatic steatosis in rats". Nutrients 9 7 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85023760594&partnerID=MN8TOARS.
    10.3390/nu9070737
  29. Pereira, L.C.; Souza, A.O.; Tasso, M.J.; Oliveira, A.M.C.; Duarte, F.V.; Palmeira, C.M.; Dorta, D.J.. "Exposure to decabromodiphenyl ether (BDE-209) produces mitochondrial dysfunction in rat liver and cell death". Journal of Toxicology and Environmental Health - Part A: Current Issues 80 19-21 (2017): 1129-1144. http://www.scopus.com/inward/record.url?eid=2-s2.0-85033371791&partnerID=MN8TOARS.
    10.1080/15287394.2017.1357370
  30. Duarte, F.V.; Amorim, J.A.; Varela, A.T.; Teodoro, J.S.; Gomes, A.P.; Cunha, R.A.; Palmeira, C.M.; et al. "Adenosine receptors: regulatory players in the preservation of mitochondrial function induced by ischemic preconditioning of rat liver". Purinergic Signalling 13 2 (2017): 179-190. http://www.scopus.com/inward/record.url?eid=2-s2.0-84995486129&partnerID=MN8TOARS.
    10.1007/s11302-016-9548-x
  31. Teodoro JS; Gomes AP; Varela AT; Duarte FV; Rolo AP; Palmeira CM. "Hepatic and skeletal muscle mitochondrial toxicity of chitosan oligosaccharides of normal and diabetic rats.". (2016): http://europepmc.org/abstract/med/27790925.
    10.1080/15376516.2016.1222643
  32. Souza AO; Tasso MJ; Oliveira AM; Pereira LC; Duarte FV; Oliveira DP; Palmeira CM; Dorta DJ. "Evaluation of Polybrominated Diphenyl Ether Toxicity on HepG2 Cells - Hexabrominated Congener (BDE-154) Is Less Toxic than Tetrabrominated Congener (BDE-47).". (2016): http://europepmc.org/abstract/med/27060917.
    10.1111/bcpt.12598
  33. Teodoro JS; Rolo AP; Jarak I; Palmeira CM; Carvalho RA. "The bile acid chenodeoxycholic acid directly modulates metabolic pathways in white adipose tissue in vitro: insight into how bile acids decrease obesity.". (2016): http://europepmc.org/abstract/med/27488269.
    10.1002/nbm.3583
  34. Alexandrino H; Varela AT; Teodoro JS; Martins MA; Rolo AP; Tralhão JG; Palmeira CM; Castro E Sousa F. "Mitochondrial bioenergetics and posthepatectomy liver dysfunction.". (2016): http://europepmc.org/abstract/med/27138992.
    10.1111/eci.12639
  35. Teodoro JS; Silva R; Varela AT; Duarte FV; Rolo AP; Hussain S; Palmeira CM. "Low-dose, subchronic exposure to silver nanoparticles causes mitochondrial alterations in Sprague-Dawley rats.". (2016): http://europepmc.org/abstract/med/27171910.
    10.2217/nnm-2016-0049
  36. Görlach A; Dimova EY; Petry A; Martínez-Ruiz A; Hernansanz-Agustín P; Rolo AP; Palmeira CM; Kietzmann T. "Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?". (2015): http://europepmc.org/abstract/med/26339717.
    10.1016/j.redox.2015.08.016
  37. Mieiro CL; Pardal M; Duarte A; Pereira E; Palmeira CM. "Impairment of mitochondrial energy metabolism of two marine fish by in vitro mercuric chloride exposure.". (2015): http://europepmc.org/abstract/med/26026249.
    10.1016/j.marpolbul.2015.05.054
  38. Rodrigues ET; Moreno A; Mendes T; Palmeira C; Pardal MÂ. "Biochemical and physiological responses of Carcinus maenas to temperature and the fungicide azoxystrobin.". (2015): http://europepmc.org/abstract/med/25835271.
    10.1016/j.chemosphere.2015.03.011
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  117. Oliveira, P.J.; Rolo, A.P.; Palmeira, C.M.; Moreno, A.J.M.. "Carvedilol reduces mitochondrial damage induced by hypoxanthine/xanthine oxidase: Relevance to hypoxia/reoxygenation injury". Cardiovascular Toxicology 1 3 (2001): 205-213. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035750084&partnerID=MN8TOARS.
    10.1385/CT:1:3:205
  118. Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M.. "Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria". Bioscience Reports 21 1 (2001): 73-80. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034899577&partnerID=MN8TOARS.
    10.1023/A:1010438202519
  119. Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M.. "Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore". Biochemical Pharmacology 61 11 (2001): 1449-1454. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035370544&partnerID=MN8TOARS.
    10.1016/S0006-2952(01)00620-7
  120. Santos, M.S.; Santos, D.L.; Palmeira, C.M.; Seiça, R.; Moreno, A.J.; Oliveira, C.R.. "Brain and liver mitochondria isolated from diabetic Goto-Kakizaki rats show different susceptibility to induced oxidative stress". Diabetes/Metabolism Research and Reviews 17 3 (2001): 223-230. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034944055&partnerID=MN8TOARS.
    10.1002/dmrr.200
  121. Zhou, S.; Palmeira, C.M.; Wallace, K.B.. "Doxorubicin-induced persistent oxidative stress to cardiac myocytes". Toxicology Letters 121 3 (2001): 151-157. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035912594&partnerID=MN8TOARS.
    10.1016/S0378-4274(01)00329-0
  122. Oliveira, P.J.; Rolo, A.P.; Sardão, V.A.; Coxito, P.M.; Palmeira, C.M.; Moreno, A.J.M.. "Carvedilol in heart mitochondria - Protonophore or opener of the mitochondrial KATP channels?". Life Sciences 69 2 (2001): 123-132. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035371154&partnerID=MN8TOARS.
    10.1016/S0024-3205(01)01109-2
  123. Oliveira, P.J.; Coxito, P.M.; Rolo, A.P.; Santos, D.L.; Palmeira, C.M.; Moreno, A.J.M.. "Inhibitory effect of carvedilol in the high-conductance state of the mitochondrial permeability transition pore". European Journal of Pharmacology 412 3 (2001): 231-237. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035793307&partnerID=MN8TOARS.
    10.1016/S0014-2999(01)00745-2
  124. Rolo AP; Oliveira PJ; Moreno AJ; Palmeira CM; Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M.. "Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy.". Toxicological Sciences 57 1 (2000): 177-185. http://europepmc.org/abstract/med/10966524.
    10.1093/toxsci/57.1.177
  125. Rolo, A.P.; Palmeira, C.M.. "Cholestasis and mitochondrial dysfunction: A review". Toxic Substance Mechanisms 19 2 (2000): 83-98. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034458883&partnerID=MN8TOARS.
    10.1080/10769180052008878
  126. Palmeira, C.M.; Rana, M.I.; Frederick, C.B.; Wallace, K.B.. "Induction of the mitochondrial permeability transition in vitro by short-chain carboxylic acids". Biochemical and Biophysical Research Communications 272 2 (2000): 431-435. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034616658&partnerID=MN8TOARS.
    10.1006/bbrc.2000.2797
  127. Ferreira FM; Seiça R; Santos MS; Palmeira CM; Ferreira, F.M.L.; Seiça, R.; Santos, M.S.; Palmeira, C.M.. "Age-related alterations in liver mitochondrial bioenergetics of diabetic Goto-Kakizaki rats.". Acta Diabetologica 36 4 (1999): 173-177. http://europepmc.org/abstract/med/10664324.
    10.1007/s005920050163
  128. Palmeira, C.M.. "Herbicide-induced mitochondrial and cellular liver toxicity: A review of paraquat, dinoseb, and 2,4-D effects". Toxic Substance Mechanisms 18 4 (1999): 187-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033457940&partnerID=MN8TOARS.
    10.1080/107691899229070
  129. Ferreira, F.M.L.; Palmeira, C.M.; Seiça, R.; Santos, M.S.. "Alterations of liver mitochondrial bioenergetics in diabetic Goto- Kakizaki rats". Metabolism: Clinical and Experimental 48 9 (1999): 1115-1119. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032857256&partnerID=MN8TOARS.
    10.1016/S0026-0495(99)90124-5
  130. Palmeira, C.M.; Ferreira, F.M.L.; Santos, D.L.; Ceiça, R.; Suzuki, K.-I.; Santos, M.S.. "Higher efficiency of the liver phosphorylative system in diabetic Goto-Kakizaki (GK) rats". FEBS Letters 458 2 (1999): 103-106. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032842698&partnerID=MN8TOARS.
    10.1016/S0014-5793(99)01144-8
  131. Serrano, J.; Palmeira, C.M.; Kuehl, D.W.; Wallace, K.B.. "Cardioselective and cumulative oxidation of mitochondrial DNA following subchronic doxorubicin administration". Biochimica et Biophysica Acta - Bioenergetics 1411 1 (1999): 201-205. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032961434&partnerID=MN8TOARS.
    10.1016/S0005-2728(99)00011-0
  132. Ferreira, F.M.L.; Palmeira, C.M.; Matos, M.J.; Seiç, R.; Santos, M.S.. "Decreased susceptibility to lipid peroxidation of Goto-Kakizaki rats: Relationship to mitochondrial antioxidant capacity". Life Sciences 65 10 (1999): 1013-1025. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033618489&partnerID=MN8TOARS.
    10.1016/S0024-3205(99)00332-X
  133. Custodio, J.B.A.; Palmeira, C.M.; Moreno, A.J.; Wallace, K.B.. "Acrylic acid induces the glutathione-independent mitochondrial permeability transition in vitro". Toxicological Sciences 43 1 (1998): 19-27. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031831694&partnerID=MN8TOARS.
    10.1006/toxs.1998.2448
  134. Moreno, A.J.M.; Santos, D.J.S.L.; Palmeira, C.M.; Moreno AJ; Santos DJ; Palmeira CM. "Ischemic heart disease: The role of mitochondria - Carvedilol prevents lipid peroxidation of mitochondrial membranes". Revista Portuguesa de Cardiologia 17 SUPPL. 2 (1998): 63-77. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031759966&partnerID=MN8TOARS.
  135. Palmeira, C.M.; Wallace, K.B.. "Benzoquinone inhibits the voltage-dependent induction of the mitochondrial permeability transition caused by redox-cycling naphthoquinones". Toxicology and Applied Pharmacology 143 2 (1997): 338-347. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030932708&partnerID=MN8TOARS.
    10.1006/taap.1996.8099
  136. Palmeira, C.M.; Madeira, V.M.C.. "Mercuric chloride toxicity in rat liver mitochondria and isolated hepatocytes". Environmental Toxicology and Pharmacology 3 3 (1997): 229-235. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030758726&partnerID=MN8TOARS.
    10.1016/S1382-6689(97)00018-5
  137. Palmeira, C.M.; Serrano, J.; Kuehl, D.W.; Wallace, K.B.. "Preferential oxidation of cardiac mitochondrial DNA following acute intoxication with doxorubicin". Biochimica et Biophysica Acta - Bioenergetics 1321 2 (1997): 101-106. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030880285&partnerID=MN8TOARS.
    10.1016/S0005-2728(97)00055-8
  138. Serrano, J.; Palmeira, C.M.; Wallace, K.B.; Kuehl, D.W.. "Determination of 8-hydroxydeoxyguanosine in biological tissue by liquid chromatography/electrospray ionization-mass spectrometry/mass spectrometry". Rapid Communications in Mass Spectrometry 10 14 (1996): 1789-1791. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030478989&partnerID=MN8TOARS.
    10.1002/(SICI)1097-0231(199611)10:14<1789::AID-RCM752>3.0.CO;2-6
  139. Palmeira, C.M.; Moreno, A.J.M.; Madeira, V.M.C.; Wallace, K.B.. "Continuous monitoring of mitochondrial membrane potential in hepatocyte cell suspensions". Journal of Pharmacological and Toxicological Methods 35 1 (1996): 35-43. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029925338&partnerID=MN8TOARS.
    10.1016/1056-8719(95)00131-X
  140. Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C.. "Thiols metabolism is altered by the herbicides paraquat, dinoseb and 2,4-D: A study in isolated hepatocytes". Toxicology Letters 81 2-3 (1995): 115-123. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029590153&partnerID=MN8TOARS.
    10.1016/0378-4274(95)03414-5
  141. Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C.. "Mitochondrial bioenergetics is affected by the herbicide paraquat". Biochimica et Biophysica Acta - Bioenergetics 1229 2 (1995): 187-192. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028961733&partnerID=MN8TOARS.
    10.1016/0005-2728(94)00202-G
  142. Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C.. "Effects of paraquat, dinoseb and 2,4-D on intracellular calcium and on vasopressin-induced calcium mobilization in isolated hepatocytes". Archives of Toxicology 69 7 (1995): 460-466. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029054234&partnerID=MN8TOARS.
    10.1007/s002040050199
  143. Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C.. "Metabolic alterations in hepatocytes promoted by the herbicides paraquat, dinoseb and 2,4-D". Archives of Toxicology 68 1 (1994): 24-31. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028009773&partnerID=MN8TOARS.
    10.1007/s002040050025
  144. Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C.. "Interactions of herbicides 2,4-D and dinoseb with liver mitochondrial bioenergetics". Toxicology and Applied Pharmacology 127 1 (1994): 50-57. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028146853&partnerID=MN8TOARS.
    10.1006/taap.1994.1138
  145. Palmeira, C.M.; Santos, M.S.; Carvalho, A.P.; Oliveira, C.R.; Palmeira CM; Santos MS; Carvalho AP; Oliveira CR. "Membrane lipid peroxidation induces changes in ¿-[3H]aminobutyric acid transport and calcium uptake by synaptosomes". Brain Research 609 1-2 (1993): 117-123. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027309463&partnerID=MN8TOARS.
    10.1016/0006-8993(93)90863-I
  146. Palmeira, C.M.; Oliveira, C.R.. "Partitioning and membrane disordering effects of dopamine antagonists: Influence of lipid peroxidation, temperature, and drug concentration". Archives of Biochemistry and Biophysics 295 1 (1992): 161-171. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026729101&partnerID=MN8TOARS.
    10.1016/0003-9861(92)90502-N
Capítulo de livro
  1. Alexandrino, H.; Rolo, A.; Tralhão, J.G.; Castro e Sousa, F.; Palmeira, C.. "Mitochondria in liver regeneration: Energy metabolism and posthepatectomy liver dysfunction". 127-152. 2018.
  2. Teodoro, J.S.; Palmeira, C.M.; Rolo, A.P.; Palmeira CM; Rolo AP. "Mitochondrial membrane potential (¿¿) fluctuations associated with the metabolic states of mitochondria". 109-119. 2018.
    10.1007/978-1-4939-7831-1_6
  3. Teodoro, João Soeiro; Palmeira, Carlos Marques; Rolo, Anabela Pinto. "Mitochondrial Membrane Potential (¿¿) Fluctuations Associated with the Metabolic States of Mitochondria". In Methods in Molecular Biology, 109-119. Springer New York, 2018.
    10.1007/978-1-4939-7831-1_6
  4. Amorim, Joao Alves; Teodoro, Joao Soeiro; Palmeira, Carlos Marques; Rolo, Anabela Pinto. "Sirtuins and Bile Acids: Potential Anti-obesity Strategies Targeting Mitochondria". In Anti-Obesity Drug Discovery and Development: Volume 4, 57-97. BENTHAM SCIENCE PUBLISHERS, 2018.
    10.2174/9781681085586118040005
  5. Alexandrino, Henrique; Rolo, Anabela; Tralhão, José Guilherme; Castro e Sousa, Francisco; Palmeira, Carlos. "Mitochondria in Liver Regeneration: Energy Metabolism and Posthepatectomy Liver Dysfunction". In Mitochondrial Biology and Experimental Therapeutics, 127-152. Springer International Publishing, 2018.
    10.1007/978-3-319-73344-9_8
  6. Palmeira, C.M.; Ramalho-Santos, J.. "Mitochondrial dysfunction in reproductive and developmental toxicity". 1023-1035. 2017.
    10.1016/B978-0-12-382032-7.10061-X
  7. Teodoro, João S.; Duarte, Filipe V.; Rolo, Anabela P.; Palmeira, Carlos M.. "Mitochondria as a Target for Safety and Toxicity Evaluation of Nutraceuticals". In Nutraceuticals, 387-400. Elsevier, 2016.
    10.1016/b978-0-12-802147-7.00028-0
  8. Duarte, Filipe V.; Palmeira, Carlos M.; Rolo, Anabela P.. "The Emerging Role of MitomiRs in the Pathophysiology of Human Disease". In Advances in Experimental Medicine and Biology, 123-154. Springer International Publishing, 2015.
    10.1007/978-3-319-22671-2_8
  9. Teodoro, J.S.; Palmeira, C.M.; Rolo, A.P.; Teodoro JS; Palmeira CM; Rolo AP. "Determination of oxidative phosphorylation complexes activities". 71-84. 2014.
    10.1007/978-1-4939-1875-1_7
  10. Teodoro, João S.; Palmeira, Carlos M.; Rolo, Anabela P.. "Determination of Oxidative Phosphorylation Complexes Activities". In Methods in Molecular Biology, 71-84. Springer New York, 2014.
    10.1007/978-1-4939-1875-1_7
  11. Palmeira, Carlos M.; Duarte, Filipe V.; Teodoro, João S.; Varela, Ana T.; Rolo, Anabela P.. "Biomarkers of mitochondrial dysfunction and toxicity". In Biomarkers in Toxicology, 847-861. Elsevier, 2014.
    10.1016/b978-0-12-404630-6.00051-8
  12. Palmeira, Carlos M.; Rolo, Anabela P.. "Mitochondrial Membrane Potential (¿¿) Fluctuations Associated with the Metabolic States of Mitochondria". In Methods in Molecular Biology, 89-101. Humana Press, 2011.
    10.1007/978-1-61779-382-0_6
Edição de livro
  1. Palmeira, Carlos M.. Mitochondrial Bioenergetics. Springer New York. 2018.
    10.1007/978-1-4939-7831-1
  2. Palmeira, Carlos M.. Mitochondrial Regulation. Springer New York. 2015.
    10.1007/978-1-4939-1875-1
  3. Palmeira, Carlos M.. Mitochondrial Bioenergetics. Humana Press. 2012.
    10.1007/978-1-61779-382-0
Edição de número de revista
  1. Palmeira, Carlos M.. "Metabolic Diseases: Drugs and Mitochondrial Targets". Current Medicinal Chemistry 22 20 (2015): http://www.eurekaselect.com/node/602/current-medicinal-chemistry/issue/22/1553/20/6495.
    Publicado
Livro
  1. Palmeira, C.M.; Moreno, A.J.. Preface. 2018.
  2. Teodoro, J.S.; Duarte, F.V.; Rolo, A.P.; Palmeira, C.M.. Mitochondria as a Target for Safety and Toxicity Evaluation of Nutraceuticals. 2016.
    10.1016/B978-0-12-802147-7.00028-0
  3. Palmeira, C.M.; Rolo, A.P.. Preface. 2014.
  4. Palmeira, C.M.; Duarte, F.V.; Teodoro, J.S.; Varela, A.T.; Rolo, A.P.. Biomarkers of mitochondrial dysfunction and toxicity. 2014.
    10.1016/B978-0-12-404630-6.00051-8
  5. Palmeira, C.M.; Rolo, A.P.. Mitochondrial Regulation: Methods and Protocols. 2014.
    10.1007/978-1-4939-1875-1
Tese / Dissertação
  1. Palmeira, Carlos M.. "Alterações metabólicas em células hepáticas de rato induzidas por herbicidas de uso generalizado". Doutoramento, Universidade de Coimbra, 1995. https://estudogeral.sib.uc.pt/handle/10316/2126?mode=full.
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2018 - Atual PhD - Effects of drugs on epicardial tissue - impact on cardiac function
Coorientador
Biociências (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018 - Atual PhD - The physiology and health condition of urban dweller gulls in increasingly urbanized areas
Coorientador
Biociências (Doutoramento)
Universidade de Coimbra, Portugal
2018 - Atual PhD - Predictive factors for non-anastomotic biliary strictures after liver ransplantation: prospective analysis of histological lesion and mitochondrial function of the bile duct in response to ischemia / re-perfusion. identification of new criteria for classification of marginality of the liver graft
Coorientador
Ciências da Saúde (Doutoramento)
Universidade de Coimbra, Portugal
2016 - 2019 PhD - Understanding the underlying mechanisms regulating aging and longevity
Coorientador
Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra, Portugal
2015 - 2018 PhD - Liver transplantation: new prognostic factors of the regulation of mitochondrial function in ischemia/reperfusion
Coorientador
Ciências da Saúde (Doutoramento)
Universidade de Coimbra, Portugal
2014 - 2018 PhD - Energy for Liver Regeneration: Mitochondrial Bioenergetics and the Pathogenesis of Posthepatectomy Liver Dyfunction
Coorientador
Ciências da Saúde (Doutoramento)
Universidade de Coimbra, Portugal
2013 - 2016 PostDoc - Joao Soeiro Terra Teodoro (SFRH/BPD/94036/2013)
Coorientador
SFRH/BPD/94036/2013 (Outra)
2013 - 2016 PostDoc - Filipe Valente Duarte (SFRH/BPD/94898/2013)
Coorientador
SFRH/BPD/94898/2013 (Outra)
2013 - 2016 PostDoc - Ana Teresa Inácio Ferreira Varela (SFRH/BPD/94886/2013)
Coorientador
SFRH/BPD/94886/2013 (Outra)
2011 - 2014 PhD - The cardiotoxicity of mitoxantrone: a mechanistic approach using in vitro and in vivo models.
Coorientador
Ciências Farmacêuticas (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2009 - 2013 PhD - Unravelling new roles for SIRT1 in mitochondrial biology
Coorientador
Biologia (Doutoramento)
Universidade de Coimbra, Portugal
2009 - 2012 PostDoc - Joana Luísa Lourenço Estevinho Pereira (SFRH/BPD/44733/2008)
Coorientador
SFRH/BPD/44733/2008 (Outra)
2009 - 2012 PhD - Physiologic pathways and molecular mechanisms regulating energy homeostasis in diabetes
Coorientador
Biociências (Doutoramento)
Universidade de Coimbra, Portugal
2009 - 2012 PhD - Regulation of mitochondrial function in ischemia/reperfusion: looking for therapeutic strategies in fatty livers
Coorientador
Biologia (Doutoramento)
Universidade de Coimbra, Portugal
2009 - 2012 PhD - Effects of exposition to dioxins and environmental pollutants: identification of biomarkers in chronic pulmonary diseases
Coorientador
Biociências (Doutoramento)
Universidade de Coimbra, Portugal
2008 - 2011 PhD - Impacto da diabetes e sua terapêutica na função cardiomiocitária na isquémia-reperfusão: estudo em modelos animais e em doentes com insuficiência cardíaca avançada
Coorientador
Biologia (Doutoramento)
Universidade de Coimbra, Portugal
2008 - 2011 PhD - The Effects of Environmental Conditions and Mercury on Common Estuarine Species. An Integrated Ecological and Toxicological Approach
Coorientador
Biologia (Doutoramento)
Universidade de Coimbra, Portugal
2007 - 2011 PhD - NMR studies on the regulation of glucose and fatty acid oxidation in liver, heart and skeletal muscle in awake rats
Coorientador
Bioquímica (Doutoramento)
Universidade de Coimbra, Portugal
2007 - 2011 PhD - Endoplasmic reticulum stress during amyloid ß peptide-induced cell death : role of mitochondria and glutamatergic N-methyl-D-aspartate receptors
Coorientador
Biologia (Doutoramento)
Universidade de Coimbra, Portugal
2007 - 2010 PostDoc - Pedro Emanuel Pato Martins (SFRH/BPD/35068/2007)
Coorientador
SFRH/BPD/35068/2007 (Outra)
2008 - 2009 PostDoc - João Gonçalo Leal de Oliveira e Silva Frade (SFRH/BPD/66253/2009)
Orientador de João Gonçalo Leal de Oliveira e Silva Frade
SFRH/BPD/66253/2009 (Outra)
Universidade de Coimbra, Portugal
2003 - 2009 PostDoc - Anabela Pinto Rolo (SFRH/BPD/14615/2003 and SFRH/BPD/26514/2006)
Orientador de Anabela Pinto Rolo
SFRH/BPD/14615/2003 and SFRH/BPD/26514/2006 (Outra)
2002 - 2006 PhD - Avaliação do efeito de extractos de plantas a nível da bioenergética mitocondrial em ratos diabéticos
Coorientador
Biologia (Doutoramento)
Universidade de Coimbra, Portugal
2000 - 2003 PhD - Cholestasis and hepatic ischemia: bile acids therapy. Cellular mechanisms with relevance to mitochondrial function
Orientador de Anabela Pinto Rolo
Biologia (Doutoramento)
Universidade de Coimbra, Portugal
2000 - 2003 PhD - Cardiac mitochondrial function:studies on the impact of disease conditions and on the protection afforded by carvedilol
Coorientador
Biologia (Doutoramento)
Universidade de Coimbra, Portugal

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2016 - Atual Perito A3ES
Avaliador
A3ES, Portugal
2015 - 2015 Concurso de bolsas individuais de doutoramento e pós-doutoramento – 2015 (FCT) Painel de avaliação: Ciências do Ambiente (Co-coordenador)
Avaliador
Fundação para a Ciência e a Tecnologia, Portugal
2014 - 2014 Concurso de bolsas individuais de doutoramento e pós-doutoramento – 2014 (FCT) Painel de avaliação: Ciências Ambientais e outras ciências naturais
Avaliador
Fundação para a Ciência e a Tecnologia, Portugal
2013 - 2013 Concurso de bolsas individuais de doutoramento e pós-doutoramento – 2013 (FCT) Painel de avaliação: Biomedicina
Avaliador
Fundação para a Ciência e a Tecnologia, Portugal

Membro de associação

Nome da associação Tipo de participação
2015 - Atual Mitochondrial Physiology Society Membro
2000 - Atual Sociedade Portuguesa de Bioquímica Membro
2000 - Atual Society of Tozixology Membro

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2015 - Atual Membro do Comité Executivo da Mitochondrial Physiology Society (desde 2015)
Vogal
Mitochondrial Physiology Society , Áustria