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Francisca Massano obtained her Bachelor’s degree in Chemical Engineering from the Faculty of Engineering of the University of Porto (FEUP) in 2022, followed by a Master’s degree in Chemical Engineering with specialization in Biotechnology, also from FEUP, in 2023. These degrees equipped her with a comprehensive theoretical and practical education spanning areas such as Physics, Engineering, Chemistry, Biochemistry, Microbiology, Biotechnology, and also Molecular Biology. During the first year of her Master’s degree, she had the opportunity to study at the Autonomous University of Madrid under the ERASMUS+ program. In the second year, she started working at the Laboratory for Process Engineering, Environment, Biotechnology and Energy (LEPABE) – FEUP. Her research focus centered on developing novel therapies to combat bacterial and biofilm-associated infections that later culminated in the development of her master’s thesis titled “Natural products as resistance-modifying agents to recycle old antibiotics”. Her work included innovative approaches, notably due to the evaluation of dual (phytochemical + antibiotic and natural deep eutectic solvents (NADES) + antibiotic) combinations. Throughout this period, she earned research experience in several experimental methodologies, such as microbiology techniques, antibiotic susceptibility tests, antimicrobial resistance studies, search for new antibiotic adjuvants, study of antimicrobial activity of phytochemicals, study of the phytochemical mode of action, biofilm control assays, microplate staining methods, colony forming units determination and production of NADES. She successfully defended her dissertation with a final grade of 18/20. This research experience also honed her skills in scientific writing, resulting in one first-author article and two oral presentations at the IJUP Conference, one presented in 2023 and the other in 2024. Additionally, her work at LEPABE-FEUP also led to involvement in other projects resulting in two scientific articles as co-author. From September to December 2023, she worked as a Research Fellow at the Biofilm Engineering Lab (BEL) - LEPABE under the project BIOMAT - Development and characterization of surfaces with antibiofilm activity for biomedical applications. This position provided her with theoretical and experimental experience in bacterial culture, biofilm assays, production of surfaces impregnated with functionalized carbon structures and handling bacteria under BLS-2 conditions. As part of this project she participated in the SurfSAFE Conference, in 2023. In May through July 2024, she will be working as a Research Fellow at CICECO – Aveiro Institute of Materials, working on the project "Development of cost-effective platforms based on ionic liquids for the purification of p53-minicircle DNA biopharmaceuticals with application in oncology". During this time, she will also be attending an Advanced Training Course in Scientific Research at the University of Aveiro.
Identificação

Identificação pessoal

Nome completo
Francisca de Sá Madeira Massano

Nomes de citação

  • Massano, Francisca

Identificadores de autor

Ciência ID
9A10-85BE-7B8A
ORCID iD
0009-0003-6155-8040

Domínios de atuação

  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biotecnologia Aplicada à Saúde
  • Ciências Naturais - Ciências Biológicas - Microbiologia
  • Ciências Médicas e da Saúde - Ciências da Saúde - Saúde Pública e Saúde Ambiental
  • Ciências da Engenharia e Tecnologias - Engenharia Química

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C1) Utilizador proficiente (C2)
Espanhol; Castelhano Utilizador independente (B2) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador proficiente (C1)
Formação
Grau Classificação
2024/05 - 2024/07
Em curso
Advanced Training Course in Scientific Research (Outros)
Universidade de Aveiro, Portugal
2023/09/01 - 2023/09/30
Concluído
Training Course in Transversal Competences in Scientific Research: Food, Innovation, Sustainability - Experimental design and data processing (Outros)
Universidade de Lisboa Instituto Superior de Agronomia, Portugal
19
2023/07/18
Concluído
Master in Chemical Engineering (Mestrado)
Especialização em Biotechnology
Universidade do Porto Faculdade de Engenharia, Portugal
"Natural products as resistance-modifying agents to recycle old antibiotics" (TESE/DISSERTAÇÃO)
2022/06/22
Concluído
Chemical Engineering (Licenciatura)
Universidade do Porto Faculdade de Engenharia, Portugal
2021/09 - 2022/01
Concluído
ERASMUS (Mestrado)
Universidad Autónoma de Madrid, Espanha
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2024/05/01 - 2024/07/31 Investigador (Investigação) Universidade de Aveiro CICECO, Portugal
2023/09/01 - 2023/12/31 Investigador (Investigação) Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2023/01 - 2023/06 Curricular Internship Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia, Portugal
Projetos

Bolsa

Designação Financiadores
2024/05/01 - 2024/07/31 Development of cost-effective platforms based on ionic liquids for the purification of p53-minicircle DNA biopharmaceuticals with application in oncology
2022.03394.PTDC
Bolseiro de Investigação
Universidade de Aveiro CICECO, Portugal
Fundação para a Ciência e a Tecnologia
2023/09/01 - 2023/12/31 BIOMAT - Development and characterisation of antibiofilm surfaces for biomedical applications
UIDP/00511/2020
Bolseiro de Investigação
Universidade do Porto Laboratório de Processos de Separação e Reacção Laboratório de Catálise e Materiais, Portugal
Universidade do Porto Laboratorio de Engenharia de Processos Ambiente Biotecnologia e Energia
Produções

Publicações

Artigo em revista
  1. Afonso, A. C.; Gomes, Inês B.; Simões, Manuel; Massano, Francisca; M. J. Saavedra. "Coaggregation dynamics in drinking water biofilms and implications for chlorine disinfection". Journal of Hazardous Materials (2024):
    Em revisão
  2. Massano, Francisca; Afonso, A. C.; Sousa, Mariana; Borges, Anabela; Simões, Manuel. Autor correspondente: Simões, Manuel. "The action of selected monoterpenes as biofilm control agents and potential antibiotic resistance modifiers". Journal of Applied Microbiology (2024):
    Em revisão
  3. Soares Teixeira, Lília; Sousa, Mariana; Massano, Francisca; Simões, Manuel; Borges, Anabela. Autor correspondente: Borges, Anabela. "Development of a hydrogel with antioxidant and antibacterial properties loaded with grape pomace extracts for topical treatment of chronic wound infections". Chemistry & Biodiversity (2024):
    Em revisão
Resumo em conferência
  1. Massano, Francisca; Sousa, Mariana; Borges, Anabela; Simões, Manuel. "The action of selected natural products as antibiotic resistance modifiers and biofilm control agents". Trabalho apresentado em Youth Research Meeting promoted by the University of Porto (IJUP), Porto, 2024.
    Aceite para publicação
  2. Massano, Francisca; Sousa, Mariana; Borges, Anabela; Simões, Manuel. "Plant products as resistance-modifying agents to recycle old antibiotics". Trabalho apresentado em Youth Research Meeting promoted by the University of Porto (IJUP), Porto, 2023.
    Publicado
Tese / Dissertação
  1. "Natural products as resistance-modifying agents to recycle old antibiotics". Mestrado, Universidade do Porto Faculdade de Engenharia, 2023. https://hdl.handle.net/10216/152339.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/05 The action of selected natural products as antibiotic resistance modifiers and biofilm control agents Youth Research Meeting promoted by the University of Porto (IJUP)
(Porto, Portugal)
2023/05 Plant products as resistance-modifying agents to recycle old antibiotics Youth Research Meeting promoted by the University of Porto (IJUP)
(Porto, Portugal)

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2024/05/08 - 2024/05/10 Participation in the 17th Young Researchers Meeting - University of Porto (IJUP) Youth Research Meeting promoted by the University of Porto (IJUP)
Universidade do Porto, Portugal
2023/09/27 - 2023/09/29 Participation in the SurfSAFE Conference which focuses on the field of surface modification and biofilm analysis, necessary to enable development of tailor-made antifouling and antimicrobial, non-toxic surfaces inspired by nature
Conferência
SurfSAFE Conference
Universidade do Porto, Portugal

Manchester Metropolitan University, Reino Unido

Rijksuniversiteit Groningen, Países Baixos

Københavns Universitet Biologisk Institut, Dinamarca
2023/05/10 - 2023/05/12 Participation in the 16th Young Researchers Meeting - University of Porto (IJUP) Youth Research Meeting promoted by the University of Porto (IJUP)
Universidade do Porto, Portugal