Full Professor at Instituto Superior Técnico (IST), ULisboa since 1995, he was the founding director of IN+, the Center for Innovation, Technology and Policy Research. He was Minister for Science, Technology and Higher Education in the Government of Portugal (Nov. 2015-Mar. 2022) and Secretary of State for Science, Technology and Higher Education (Mar. 2005-Jun. 2011). In 2022 he received the Honorary Doctor in Science and Technology from Carnegie Mellon University and was nominated IST distinguished Professor. He is Honorary Member of the European Academy of Cancer Sciences, Corresponding Member of the Royal Academy of Engineering, Spain, and foreign member of the Serbian Academy of Engineering Sciences. After his degree in Mechanical Engineering (1981), he obtained his PhD at the Imperial College London (1985) in the area of fluid mechanics and combustion. In 1986 he conducted post-doctoral studies at the University of California-San Diego in microgravity flame propagation. He was Deputy-President of IST in 1993-1998. In addition, he has worked and published extensively in the interrelated fields of technology management, innovation, and science and higher education policy. In 2011-12 he was a Visiting Scholar at Harvard University (GSD and Kennedy School). In 2022-23 he was a Visiting Research Professor at New York University (CUSP and Marron Institute) and a Visiting Scholar at Harvard University’s GSD. In the Government of Portugal, he was successfully involved in attracting public and private investment in R&D, growing the research landscape, and in the reform and modernization of higher education. He launched the program Go-Portugal – Global S&T Partnerships Portugal and was instrumental in forming international consortia for research, advanced education and technology commercialization activities with several US universities (MIT, Carnegie Mellon, UT Austin, Harvard). In 2023 was appointed by the European Commission as Chair of the High Level Group for the evaluation of the European Framework Program, Horizon Europe (2021-2027) and to design the next program for 2028-2034. He participated in several international fora on science, technology and innovation policy, and represented Portugal in the OECD’s initiative on Steering and Funding of Public Research and its Futures Programme. He was a founding member of the S&T Council of the International Risk Governance Council. In 2002 he was co-founder of Globelics: Global Network for the Economics of Learning, Innovation, and Competence-building Systems; until 2005 he was member of its Scientific Board and co-Director of the Globelics Academy. Since 1995 he has been a Research Fellow of the IC2 Institute - UT Austin. He was the founding director of IN+, named in 2005 one of the top 50 global research centers in technology management by the International Association of Management of Technology. He launched programmes in S&T commercialization (IMPACT and VECTORe Programs - 1997-2005), as well as the master programs on Engineering Policy and Management of Technology (1998) and Engineering Design (2002). He also launched the IST Design Studio (2002). In 1999 he was appointed National Coordinator of the Research Assessment Exercise by the Portuguese Ministry of S&T. In 2003 he coordinated a national initiative/exhibition on the history of engineering in Portugal in the 20th century, which won the Dibner Award of the Society for the History of Technology. He has published 130+ scientific articles and supervised 40+ post-grad students. Co-author of New Ideas for the University (IST Press, 1998) and Innovation for All? (Praeger, 2005), and co-editor of the book series on Technology Policy and Innovation, launched by Greenwood Publ. and continued by Purdue University Press. He is on the Advisory Boards of the journals Technological Forecasting and Social Change and the International Journal of Technology, Policy and Management, where he was guest editor in several special Issues.