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Lisete is a Researcher at the Department of Chemistry and Biochemistry at Faculty of Sciences University of Porto (FCUP), Portugal, since September 2023. She is also an Honorary Research Associate in the Glycosciences Laboratory at Imperial College London (ICL), since 2019. Lisete obtained her BSc degree in Chemistry in 2007 at FCUP, and completed her MSc in Chemistry with food specialisation in 2008, at the same University. Her PhD degree in Biochemistry was obtained in 2014 at University of Aveiro (UA), in collaboration with the GlycoLab: Functional Glycobiology at FCT-NOVA (Lisbon, Portugal) and the Glycosciences Laboratory. PhD IN BIOCHEMISTRY: Lisete focused on the structural analyses of lipopolysaccharides (LPS) from clinical isolates of H. pylori by GC-MS and ESI-MSn, and on the development of a bacterial LPS microarray for interaction studies with glycan-binding proteins and human sera. POST-DOCTORAL STUDIES IN GLYCOBIOLOGY AND BIOCHEMISTRY: Her knowledge on the structural (bio)chemistry of complex carbohydrates, combined with her passion for the glycobiology field and expertise on glycan microarrays, have led her to a Research Associate position in the pioneer glycan microarray team (Glycosciences Lab.) at ICL, in March 2015; and in November 2015, she was named Deputy Microarray Project Leader and had a leading role in the Facility management. In parallel, Lisete carried out investigations of different liposomal formulations for lipid-linked glycan probes in neoglycolipid (NGL)-based microarrays with respect to the binding signals they elicit in microarray analyses. These studies led to the construction of a new version of a broad-spectrum microarray of ~ 900 natural or synthetic lipid-linked sequence-defined glycan probes (one of the two largest glycan libraries in the world) for the Wellcome-Trust supported Carbohydrate Microarray Facility, suitable for screening analyses of a variety of carbohydrate recognition systems of biological and medical impact and able to serve the scientific community as international resources. During 2015-2019, Lisete actively contributed and provided leadership support to biotechnology and biomedicine R&D projects (translational research); collaborated with 50+ national and international academic and industrial teams that have resulted in > £30k of revenue for facility services. As an Honorary Research Associate in the Glycosciences Laboratory, Lisete is currently providing consultancy advice to the group regarding microarray equipment and training to the new staff members, assisting with microarray experiments, data analysis and preparation of manuscripts. Back to UA (2019-2022), Lisete’s work focused on the development of galactomannan-based microparticles, obtained from different natural sources, for pulmonary drug delivery. The structural variability of the different galactomannans was evaluated using conventional analytical tools and complemented with interaction studies with glycan-binding proteins of various recognition systems using glycan microarrays. Currently, at FCUP, Lisete is a team member of the research project “InsectERA - The ERA of the insect industry”. This Mobilizing Agenda for Business Innovation, framed in the Portuguese Recovery and Resilience Plan (PRR) aims to enable the industrialization and commercialization of innovative products based on insects, both in the food area (animal and human food), as well as in other industries (cosmetics or bioplastics) or in the innovative sector of bioremediation. Aiming to use insects as a healthy and sustainable alternative nutritional source in new product lines for human consumption, Lisete is focused on the extraction and characterization of the protein profile from different insect-derived flours, and on the evaluation of the insect protein digestibility, their potential allergenicity and immunogenicity.
Identificação

Identificação pessoal

Nome completo
Lisete Machado e Silva
Género
Feminino

Nomes de citação

  • Silva, Lisete M.
  • Silva, Lisete
  • Silva, L
  • Silva, LM

Identificadores de autor

Ciência ID
821E-7470-0086
ORCID iD
0000-0003-4876-5240
Researcher Id
AAD-7415-2020

Endereços de correio eletrónico

  • lisete.silva@fc.up.pt (Profissional)

Moradas

  • Department of Chemistry, University of Aveiro; Campus Universitário de Santiago, 3810-193, Aveiro, Aveiro, Portugal (Profissional)
  • Glycosciences Laboratory , Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Burlington Danes Building Hammersmith Campus, Du Cane Rd, W12 0NN, London , London , Reino Unido (Profissional)
  • Rua do Campo Alegre, s/n, 4169-007, Porto, Porto, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Bioquímica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Formação
Grau Classificação
2018/11
Frequentou
Annual Immunology Short Course for Clinicians and Scientists (Outros)
Especialização em Course
Imperial College London, Reino Unido
2018
Frequentou
Mental Health First Aid course (Outros)
Especialização em Course
Imperial College London, Reino Unido
2018
Frequentou
How Intellectual Property Rights Can Impact Your Research - Course (Outros)
Especialização em Course
Imperial College London, Reino Unido
2014
Concluído
Biochemistry (Doutoramento)
Especialização em Biochemistry (clinical branch)
Universidade de Aveiro, Portugal
"Structural analysis of glycans and development of microarrays from Helicobacter pylori cell surface glycome." (TESE/DISSERTAÇÃO)
Approved by unanimity
2008
Concluído
Chemistry (Mestrado)
Especialização em Food branch
Universidade do Porto Faculdade de Ciências, Portugal
"Evaluation of the oxidative stability of vegetable oils and olive oil compounds with anti-atherosclerotic activity during food processing. " (TESE/DISSERTAÇÃO)
18/20
2007
Concluído
Chemistry (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Isolation of olive oil compounds with anti-atherosclerotic activity during roasted food processing." (TESE/DISSERTAÇÃO)
14/20
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2023/09/01 - Atual Investigador (Investigação) Universidade do Porto Faculdade de Ciências, Portugal
Universidade do Porto Faculdade de Ciências, Portugal
2019 - Atual Investigador visitante (Investigação) Imperial College London Glycosciences Laboratory, Reino Unido
Imperial College London Glycosciences Laboratory, Reino Unido
2019/04/01 - 2022/06/30 Investigador (Investigação) Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2015/03 - 2019/04 Investigador (Investigação) Imperial College London Glycosciences Laboratory, Reino Unido
2009/05 - 2010/08 Estagiário de Investigação (Investigação) Universidade de Aveiro, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2015 - 2019 Leitor (Docente Universitário) Imperial College London, Reino Unido
Projetos

Bolsa

Designação Financiadores
2018/09 - 2021/08 GLYCOINTERACT: Glycan-human microbiome interaction: glycan diversity and recognition in the human gut with impact on health and nutrition
PTDC/BIA-MIB/31730/2017
Fundação para a Ciência e a Tecnologia
Em curso
2016/06 - 2017 Chikungunya Virus Replication and Pathogenesis
Investigador
National Institute of Allergy and Infectious Diseases
2013/07 - 2014/12 Pylori GlycoArrays: Development of microarrays from Helicobacter pylori cell surface glycome toward immunological and serological studies Fundação para a Ciência e a Tecnologia

Projeto

Designação Financiadores
2023/09/01 - Atual InsectERA - The ERA of the insect industry
C644917393-00000032
Investigador
Universidade do Porto Faculdade de Ciências, Portugal
Em curso
2019/04/01 - 2022/06/30 PulManCar: Microparticles design for active compounds pulmonary delivery using insulin as model
POCI-01-0145-FEDER-029560
Investigador
Universidade de Aveiro, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018/07/01 - 2022/06/30 Microparticles design for active compounds pulmonary delivery using insulin as model
PTDC/EQU-EPQ/29560/2017
Universidade de Aveiro, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2018/04 - 2019/03 Host-microbiota interactions in the pathology of preterm birth
22-FY18-82
Investigador
Imperial College London - Hammersmith Campus, Reino Unido
Em curso
2015/08 - 2018/08 Carbohydrate Microarray Facility for Biomedical Exploitation
Investigador
Wellcome Trust
2017/05 - 2018/04 Guillain Barre syndrome antibodies during Zika and Chikungunya vaccine trials
87242-544164
Investigador
Imperial College London - Hammersmith Campus, Reino Unido
Innovate UK
Concluído
2015/10 - 2016/10 Chemo-enzymatic production of specialty glycans
Investigador
Biotechnology and Biological Sciences Research Council
Produções

Publicações

Artigo em conferência
  1. Akune, Yukie; Aspinar, Sena; Silva, Lisete; Stoll, Mark; Palma, Angelina S.; Liu, Yan; Ranzinger, Rene; Feizi, Ten. "CarbArrayART: Carbohydrate Array Analysis and Reporting Tool New software for glycan array for data processing, storage and presentation". Trabalho apresentado em Annual Meeting of the Society for Glycobiology, New Orleans, LA, 2018.
    Publicado
  2. Akune, Yukie; Arpinar, Sena; Stoll, Mark; Silva, Lisete; Palma, Angelina S.; Liu, Yan; Ranzinger, Rene; Feizi, Ten. "New software for glycan array for data processing, storage and presentation". Trabalho apresentado em Annual Meeting of the Society for Glycobiology, Portland, OR, 2017.
    Publicado
  3. Correia, Viviana G.; Brás, Joana Luís Armada; Liu, Yan; Silva, Lisete; Zhang, Yibing; Pinheiro, Benedita; Romão, Maria João C.; et al. "An integrative strategy to decipher glycan recognition in the human gut microbiome.". Trabalho apresentado em Annual Meeting of the Society for Glycobiology, New Orleans, LA, 2016.
    Publicado
  4. Silva, Lisete M.; Childs, R.A.; Palma, Angelina S.; Chai, Wengang; Feizi, Ten; Liu, Yan. "Influence of carrier lipid composition on glycan recognition in NGL-based microarrays.". Trabalho apresentado em Annual Meeting of the Society for Glycobiology, San Francisco, CA, 2015.
    Publicado
Artigo em revista
  1. Sofia F. Reis; Susana Messias; Rita Bastos; Vítor J. Martins; Viviana G. Correia; Benedita A. Pinheiro; Lisete M. Silva; et al. "Structural differences on cell wall polysaccharides of brewer's spent Saccharomyces and microarray binding profiles with immune receptors". Carbohydrate Polymers (2023): http://dx.doi.org/10.1016/j.carbpol.2022.120325.
    10.1016/j.carbpol.2022.120325
  2. Marie N. Sorin; Antonio Di Maio; Lisete M. Silva; Domenic Ebert; Clément P. Delannoy; Ngoc-Khanh Nguyen; Yann Guerardel; et al. "Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus". Cell Reports (2023): http://dx.doi.org/10.1016/j.celrep.2023.112114.
    10.1016/j.celrep.2023.112114
  3. Meriam Shahin; Devon Sheppard; Claire Raynaud; Jamie-Lee Berry; Ishwori Gurung; Lisete M. Silva; Ten Feizi; Yan Liu; Vladimir Pelicic. "Characterisation of a glycan-binding complex of minor pilins completes the analysis of Streptococcus sanguinis type 4 pili subunits". Proceedings of the National Academy of Sciences (2023): http://dx.doi.org/10.1073/pnas.2216237120.
    10.1073/pnas.2216237120
  4. Sofia F. Reis; Vítor J. Martins; Rita Bastos; Tânia Lima; Viviana G. Correia; Benedita Pinheiro; Lisete M. Silva; et al. "Feasibility of Brewer's Spent Yeast Microcapsules as Targeted Oral Carriers". Foods (2023): http://dx.doi.org/10.3390/foods12020246.
    10.3390/foods12020246
  5. Yukie Akune; Sena Arpinar; Lisete M Silva; Angelina S Palma; Virginia Tajadura-Ortega; Kiyoko F Aoki-Kinoshita; René Ranzinger; Yan Liu; Ten Feizi. "CarbArrayART: a new software tool for carbohydrate microarray data storage, processing, presentation, and reporting". Glycobiology (2022): https://doi.org/10.1093/glycob/cwac018.
    10.1093/glycob/cwac018
  6. Valente, Sara A.; Silva, Lisete M.; Lopes, Guido R.; Sarmento, Bruno; Coimbra, Manuel A.; Passos, Cláudia P.. "Polysaccharide-based formulations as potential carriers for pulmonary delivery - A review of their properties and fates". Carbohydrate Polymers 277 (2022): 118784. http://dx.doi.org/10.1016/j.carbpol.2021.118784.
    Publicado • 10.1016/j.carbpol.2021.118784
  7. Viviana G. Correia; Filipa Trovão; Benedita A. Pinheiro; Joana L. A. Brás; Lisete M. Silva; Cláudia Nunes; Manuel A. Coimbra; et al. "Mapping Molecular Recognition of ß1,3-1,4-Glucans by a Surface Glycan-Binding Protein from the Human Gut Symbiont Bacteroides ovatus". Microbiology Spectrum 9 3 (2021): https://doi.org/10.1128/Spectrum.01826-21.
    Publicado • 10.1128/Spectrum.01826-21
  8. Li, Chunxia; Palma, Angelina S; Zhang, Pengtao; Zhang, Yibing; Gao, Chao; Silva, Lisete M; Li, Zhen; et al. "Noncovalent microarrays from synthetic amino-terminating glycans: Implications in expanding glycan microarray diversity and platform comparison". Glycobiology 31 8 (2021): 931-946. http://dx.doi.org/10.1093/glycob/cwab037.
    Acesso aberto • Publicado • 10.1093/glycob/cwab037
  9. Lisete M. Silva; Viviana G. Correia; Ana S.P. Moreira; Maria Rosário M. Domingues; Rui M. Ferreira; Céu Figueiredo; Nuno F. Azevedo; et al. Autor correspondente: Lisete M. Silva. "Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays". Carbohydrate Polymers (2020): 117350-117350. https://doi.org/10.1016/j.carbpol.2020.117350.
    Acesso aberto • Publicado • 10.1016/j.carbpol.2020.117350
  10. Nicole McAllister; Yan Liu; Lisete M. Silva; Anthony J. Lentscher; Wengang Chai; Nian Wu; Kira A. Griswold; et al. "Chikungunya virus strains from each genetic clade bind sulfated glycosaminoglycans as attachment factors". Journal of Virology (2020): https://doi.org/10.1128/JVI.01500-20.
    Publicado • 10.1128/JVI.01500-20
  11. Vendele, Ingrida; Willment, Janet A.; Silva, Lisete M.; Palma, Angelina S.; Chai, Wengang; Liu, Yan; Feizi, Ten; et al. "Mannan detecting C-type lectin receptor probes recognise immune epitopes with diverse chemical, spatial and phylogenetic heterogeneity in fungal cell walls". PLOS Pathogens 16 1 (2020): e1007927. http://dx.doi.org/10.1371/journal.ppat.1007927.
    Publicado • 10.1371/journal.ppat.1007927
  12. Wu, N.; Silva, L.M.; Liu, Y.; Zhang, Y.; Gao, C.; Zhang, F.; Fu, L.; et al. "Glycan markers of human stem cells assigned with beam search arrays". Molecular and Cellular Proteomics 18 10 (2019): 1981-2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072849227&partnerID=MN8TOARS.
    Publicado • 10.1074/mcp.RA119.001309
  13. Chandra, N.; Liu, Y.; Liu, J.-X.; Frängsmyr, L.; Wu, N.; Silva, L.M.; Lindström, M.; et al. "Sulfated glycosaminoglycans as viral decoy receptors for human adenovirus type 37". Viruses 11 3 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85062951333&partnerID=MN8TOARS.
    Publicado • 10.3390/v11030247
  14. Rudkin, F.M.; Raziunaite, I.; Workman, H.; Essono, S.; Belmonte, R.; MacCallum, D.M.; Johnson, E.M.; et al. "Single human B cell-derived monoclonal anti-Candida antibodies enhance phagocytosis and protect against disseminated candidiasis". Nature Communications 9 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85058242231&partnerID=MN8TOARS.
    Publicado • 10.1038/s41467-018-07738-1
  15. Loureiro, L.R.; Sousa, D.P.; Ferreira, D.; Chai, W.; Lima, L.; Pereira, C.; Lopes, C.B.; et al. "Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2–6 sialic acids". Scientific Reports 8 1 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85051658578&partnerID=MN8TOARS.
    Publicado • 10.1038/s41598-018-30421-w
  16. Li, Z.; Gao, C.; Zhang, Y.; Palma, A.S.; Childs, R.A.; Silva, L.M.; Liu, Y.; et al. "O-glycome beam search arrays for carbohydrate ligand discovery". Molecular and Cellular Proteomics 17 1 (2018): 121-133. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040257214&partnerID=MN8TOARS.
    Publicado • 10.1074/mcp.RA117.000285
  17. Liu, Y.; McBride, R.; Stoll, M.; Palma, A.S.; Silva, L.; Agravat, S.; Aoki-Kinoshita, K.F.; et al. "The minimum information required for a glycomics experiment (MIRAGE) project: Improving the standards for reporting glycan microarray-based data". Glycobiology 27 4 (2017): 280-284. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019624012&partnerID=MN8TOARS.
    Publicado • 10.1093/glycob/cww118
  18. Nunes, C.; Silva, L.; Fernandes, A.P.; Guiné, R.P.F.; Domingues, M.R.M.; Coimbra, M.A.. "Occurrence of cellobiose residues directly linked to galacturonic acid in pectic polysaccharides". Carbohydrate Polymers 87 1 (2012): 620-626. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054737677&partnerID=MN8TOARS.
    Publicado • 10.1016/j.carbpol.2011.08.027
  19. Silva, Lisete M.; Pinto, Joana; Carrola, Joana; Paiva-Martins, Fátima. "Oxidative stability of olive oil after food processing and comparison with other vegetable oils". Food Chemistry 121 4 (2010): 1177-1187. http://dx.doi.org/10.1016/j.foodchem.2010.02.001.
    Publicado • 10.1016/j.foodchem.2010.02.001
  20. Paiva-Martins, F.; Fernandes, J.; Santos, V.; Silva, Lisete; Borges, F.; Rocha, S.; Belo, L.; Santos-Silva, A.. "Powerful Protective Role of 3,4-Dihydroxyphenylethanol-Elenolic Acid Dialdehyde against Erythrocyte Oxidative-Induced Hemolysis". Journal of Agricultural and Food Chemistry 58 1 (2010): 135-140. http://dx.doi.org/10.1021/jf9031052.
    Publicado • 10.1021/jf9031052
  21. Silva, L.; Garcia, B.; Paiva-Martins, F.. "Oxidative stability of olive oil and its polyphenolic compounds after boiling vegetable process". LWT - Food Science and Technology 43 9 (2010): 1336-1344. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954027971&partnerID=MN8TOARS.
    Publicado • 10.1016/j.lwt.2010.05.013
Capítulo de livro
  1. Silva, Lisete; Shahidi, Fereidoon; Coimbra, Manuel A.. "Dried Pears: Phytochemicals and Potential Health Effects". In Dried Fruits, 325-356. Blackwell Publishing Ltd., 2013.
    Publicado • 10.1002/9781118464663.ch18
  2. Ferreira, José; Silva, Lisete; Monteiro, Mario; Coimbra, Manuel A.. "Helicobacter pylori cell-surface glycans structural features: Role in gastric colonization, pathogenesis, and carbohydrate-based vaccines". 160-193. 2011.
    Publicado • 10.1039/9781849732765-00160
  3. Silva, Lisete M.. "Isolamento e caracterização estrutural de polissacarídeos pécticos da pêra passa de Viseu". In Secagem de Peras. Da tradição à ciência, 205-2014. Viseu, Portugal: CI&DETS, Viseu, 2010.
    Publicado
Poster em conferência
  1. Bárbara Oliveira; Silva, Lisete M.; Coimbra, Manuel A.. "THE NATURE OF CARBOHYDRATES AND PHENOLIC COMPOUNDS IN POMEGRANATE SKINS". Trabalho apresentado em XV Portuguese Meeting in Food Chemistry, 2021.
  2. Trovão, Filipa; Correia, Viviana G.; Lourenço, Frederico; Brás, Joana L. A.; Silva, Lisete M.; Paulsen, Berit S.; Feizi, Ten; et al. "Characterisation of a novel CBM from human gut microbiota provides further insight into the bacterial degradation of complex pectic polysaccharides.". Trabalho apresentado em 22nd EMBL PhD Symposium: The Roaring 20s, 2020.
  3. Passos, Cláudia; Silva, Lisete M.. "Preparation of microparticles for pulmonary administration of insulin using coffee polysaccharides as protein carriers.". Trabalho apresentado em 6th EPNOE International Polysaccharide Conference, 2019.
  4. Silva, Lisete M.; Rocha, Júlio; Lopes, Guido R.; Bastos, Ana; Almeida, Margarida; Coimbra, Manuel A.; Passos, Claudia P.. "Microwave effect on the physicochemical properties of Locust bean gum microparticles - preparation for application in pulmonary drug delivery". Trabalho apresentado em 6th EPNOE - International Polysaccharide Conference, 2019.
  5. Correia, Viviana G.; Lourenço, Frederico; Trovão, Filipa; Brás, Joana L. A.; Andrade Pinheiro, Benedita; Silva, Lisete M.; Feizi, Ten; et al. "A novel pectin binding protein from the human gut microbiota". Trabalho apresentado em 7th National Meeting of Portuguese Users of Synchrotron Radiation (ENURS), 2018.
  6. Silva, Lisete; Moreira, Ana S. P.; Domingues, M. Rosário M.; Palma, A.; José Alexandre Ferreira; Coimbra, M. A.. "Helicobacter pylori cell-surface glycans: Occurrence and structural insights towards development of a novel pathogen microarray". Trabalho apresentado em International conference on challenges in chemistry and biology of carbohydrates (CARBO-XXVIII), 2014.
Pré-impressão
  1. Nils H. Rustmeier; Lisete M. Silva; Antonio Di Maio; Joshua C. Müller; Alexander Herrmann; Ten Feizi; Yan Liu; Thilo Stehle. "A novel and highly specific Forssman antigen-binding protein from sheep polyomavirus". 2023. https://doi.org/10.1101/2023.04.10.536218.
    10.1101/2023.04.10.536218
Resumo em conferência
  1. Valente, Sara; Lopes, Guido R.; Silva, Lisete; Almeida, Margarida; Ferreira, Paula; Coimbra, Manuel A.; Passos, Cláudia. "Spent coffee grounds as a food byproducts source of polysaccharide with application as carriers for pulmonary insulin delivery". Trabalho apresentado em Dare2Change conference, Porto, 2021.
  2. Valente, Sara; Lopes, Guido R.; Silva, Lisete; Almeida, Margarida; Ferreira, Paula; Coimbra, Manuel A.; Passos, Cláudia. "FROM SPENT COFFEE GROUNDS TO POLYSACCHARIDE-BASED MICROPARTICLES FOR PULMONARY INSULIN DELIVERY". Trabalho apresentado em Waste2Value International Congress, Online, 2021.
  3. Valente, Sara A.; Silva, Lisete M.; Lopes, Guido R.; Almeida, Margarida; Coimbra, Manuel A.; Passos, Claudia P.. "Development of galactomannan-based microparticles for pulmonary insulin delivery". Trabalho apresentado em 7th Portuguese Young Chemists Meeting, Online, 2021.
  4. Valente, Sara A.; Silva, Lisete M.; Lopes, Guido R.; Almeida, Margarida; Coimbra, Manuel A.; Passos, Claudia P.. "Development of polysaccharide-based carriers for pulmonary insulin delivery". Trabalho apresentado em 4th EPNOE Junior Scientist Meeting, Online, 2021.
Tese / Dissertação
  1. Silva, Lisete Machado e. "Structural analysis of glycans and development of microarrays from Helcobacter pylori cell surface glycome". Doutoramento, 2014. http://hdl.handle.net/10773/15453.
  2. Silva, Lisete Machado e. "Determinação da estabilidade de óleos e de compostos com actividade anti-aterosclerótica do azeite durante o processamento de alimentos". Mestrado, 2008. http://hdl.handle.net/10216/64173.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2019/07 The biochemical principles and applications of carbohydrate microarrays XXVI Portuguese Chemical Society meeting 2019
(Porto, Portugal)
2017 Glycan microarrays in biological and medical research. 12th Meeting of the Portuguese Carbohydrate Group (Glupor 12)
Portuguese Carbohydrate Group (Aveiro, Portugal)
2016/06/03 Neoglycolipid-based carbohydrate microarray technology: principles and applications
Universidade de Aveiro (Aveiro, Portugal)
2015 Insights into Helicobacter pylori lipopolysaccharide structural domains using a pathogen carbohydrate microarray. 11th International Meeting of the Portuguese Carbohydrate Group – GLUPOR 11 – and 6th Iberian Carbohydrate Meeting
(Viseu, Portugal)
2014 Probing structural domains of H. pylori lipopolysaccharides with glycan binding proteins using microarrays. Glyco-T 2014, 9th International Symposium on Glycosyltransferases
(Porto, Portugal)
2014 Helicobacter pylori cell-surface glycans: Isolation and structural characterization towards development of a novel pathogen microarray. Glyco-T 2014, 9th International Symposium on Glycosyltransferases.
(Porto)
2013 Helicobacter pylori cell surface glycans: Isolation and structural characterization towards development of a novel pathogen microarray. REQUIMTE research group of Chemistry Department of FCT-UNL, Lisbon
2013 Helicobacter pylori cell-surface glycans: Isolation and structural characterization towards development of a novel pathogen microarray. GLUPOR 10 and 1st Workshop of Carbohydrates
(Covilhã, Portugal)
2013 GC-MS as a tool towards identification of typical sugars occurred in Helicobacter pylori lipopolysaccharides. 8º Encontro Nacional de Cromatografia
(Covilhã, Portugal)
2013 Evaluation of the stress-induced growth of the Portuguese clinical isolate Helicobacter pylori CI-5 strain - a structural characterization of cell-surface lipopolysaccharides. MicroBiotec 13
(Aveiro, Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2020/09 - 2021/12/06 Interaction study between carob galactomannans and proteins using carbohydrate microarray tecnology
Orientador
Biochemistry (Mestrado)
Universidade de Aveiro, Portugal
2021/02 - 2021/09/17 Água da demolha: o subproduto das leguminosas.
Coorientador
Biochemistry (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2021/02 - 2021/07/23 Improving aquafaba production: The effect of sodium bicarbonate.
Coorientador
Biotechnology (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2020/02 - 2020/07 Aquafaba - uma alternativa vegan às claras do ovo: estudo das propriedades físico-químicas visando a formulação e desenvolvimento de novos produtos.
Orientador
Biochemistry (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2020/02 - 2020/07 Microcápsulas de levedura para aplicações biomédicas.
Coorientador
Biochemistry (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2019/10/10 - 2019/10/12 Demonstration of galactomannan-based microparticles for insulin pulmonary delivery
Exposição
TechDays 2019
Universidade de Aveiro, Portugal
2019/09/27 - 2019/09/27 Demonstration of pulmonary insulin delivery using polysaccharide-based carriers.
Exposição
European Researchers’ Night
Universidade de Aveiro, Portugal
2018 - 2018 Glycosciences Laboratory (UK)_ Demonstration on how viruses seek out their sugar chain code. "Sugar maker" interactive activities with the public.
Festival
White City Mash Up
Imperial College London, Reino Unido
2017 - 2017 Glycosciences Laboratory (UK)_Demonstration entitled "Microchips to tell how viruses seek out their sugar chain code" and consisting of: poster, microarray slides demonstration and interactive activities with the public (age 3+) such as "Sugar maker": build "sugar receptors" of different viruses using foam stickers of different shapes and colours; 2018's update of the "Sugar maker" activity: production of sugar chains bracelets, necklaces or keyrings made out of beads to take home.
Festival
Imperial College Festival
Imperial College London, Reino Unido
2013 - 2013 Helicobacter pylori polysaccharides: occurrence and structural features.
Oficina (workshop)
2nd Workshop in Mass Spectrometry and Carbohydrates
Universidade de Aveiro, Portugal

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2019/04 - Atual Providing consultancy advice to the Glycosciences Lab regarding microarray equipment and training to the new staff members, assisting them with glycan microarray experiments and protein binding data analysis. Imperial College London - Hammersmith Campus, Reino Unido
2018 - Atual Peer-reviewing in international journals: Carbohydrate Polymers, Molecular Oncology and Pharmaceutical Biology.

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2021/03 - 2021/07 Practical modules of the Curricular Unit of General Chemistry (Licenciatura) Universidade de Aveiro, Portugal
2021/05/13 - 2021/05/14 Training course on Glycan Microarrays: practical aspects of neoglycolipid (NGL)-based microarrays. Glycosciences Laboratory, Imperial College London
2018/12/11 - 2018/12/11 Invited lecture on Glycobiology (MODULE 4: IMMUNE REGULATION) as part of MSc Immunology Course (Master) Imperial College London - Hammersmith Campus, Reino Unido
2017/12/12 - 2017/12/12 Invited lecture on Glycobiology (MODULE 4: IMMUNE REGULATION) as part of MSc Immunology Course (Master) Imperial College London - Hammersmith Campus, Reino Unido
2015/12/11 - 2015/12/11 Invited lecture on Glycobiology (MODULE 4: IMMUNE REGULATION) as part of MSc Immunology Course (Master) Imperial College London - Hammersmith Campus, Reino Unido

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2021 - Atual Member of Thesis Advisory Committee of the PhD student Viviana G. Correia.
Consultor
Distinções

Prémio

2015 Travel award ($500)
Society for Glycobiology, Estados Unidos
2010 4-year post-graduate PhD research fellowship funded by FCT (SFRH/BD/71455/2010)
Fundação para a Ciência e a Tecnologia, Portugal