Liane Moura (8110-8802-8E65)

Curriculum Vitae

Liane Moura

Liane Moura obtained her Ph.D. in Biotechnology in 2013 (University of Coimbra). Liane is a member of the BioNanoSciences group at iMed.ULisboa. From 2014-2019, Liane was a Post-Doctoral fellow and used a rational approach to design multifunctional poly (glutamic acid)-dendrimers to target dendritic cells and co-deliver antigens and adjuvants for the activation of APC. Since 2019, Liane is a Junior Researcher in the Faculty of Pharmacy, University of Lisbon. Understanding the complexity of tumor microenvironment (TME) and how tumor-stromal-microbiota-neuro-immune cell interplay impacts the efficacy of cancer nanovaccines are major research interests of Liane. In parallel, Liane is working on the development of polypeptide-based nanocarriers as immunotherapeutic approaches, able to conjugate and deliver different active biomolecules to immune and cancer cells, for cancer treatment. Liane has developed nano-engineered vaccines to modulate of the tumor-associated microbiota and TME immune profiling for different cancers. Liane is the PI of a project “Nano-immunotherapy to regulate immune profiling and microbiome in pancreatic cancer”. Recently, Liane is interested in deepening the impact of tumor-associated nerves in tumor progression. Liane has been a core member within the team of other cancer nanoimmune-related research projects ongoing in the lab. Since 2018, Liane is involved in the support of practical classes teaching in the FFUL, having a postgraduate course in Pedagogy in Higher Education. Since 2023, Liane is a Guest Editor of Pharmaceutics Journal. Liane is the first author of 1 invited book chapter and 9 peer-reviewed international papers (plus 1 under revision) and co-author of the other 12 (plus 1 under revision; 2 submitted). She has 1627 citations and an h-index of 17 (by Scopus). The list includes top specialty journals (Nature Nanotechnology, Advanced Science, Seminars in Immunology). Liane has 19 communication abstracts published in international journals with impact factor, 28 selected oral communications, and 67 presentations as poster (2 as corresponding author). Liane has developed various collaborations and participated actively in laboratory management. She was awarded 12 grants from renowed scientific societies. She was involved in the organization of scientific meetings for the dissemination of science and she is a member of various national/international scientific societies. Liane is an external reviewer of Cost Action proposals and various scientific journals. Liane has participated in diverse national and international funded projects (as Co-PI and team member). She supervises various undergraduate students (2 ongoing; 9 finished), master students (4 finished) as well as ERASMUS students (2 ongoing; 3 finished). Liane also participated as Jury member in Master Thesis.

Ler resumo completo ↓

Identificação

Identificação pessoal

Nome completo: Liane Moura
Data de nascimento: 1986/04/01
Género: Feminino

Nomes de citação

Moura, Liane I F

Identificadores de autor

Ciência ID: 8110-8802-8E65
ORCID iD: 0000-0003-4264-6865
Google Scholar ID: https://scholar.google.pt/citations?hl=ptBR&user=iZwCbtwAAAAJ
Researcher Id: F-6534-2015
Scopus Author Id: 37661789300

Endereços de correio eletrónico

lmoura@ff.ulisboa.pt (Profissional)
moura.liane@gmail.com (Pessoal)

Telefones

Telefone

217946400 (Profissional)

Moradas

iMed.ULisboa. Avenida Professor Gama Pinto, 1649-003, Lisboa – Portugal, Lisboa, Portugal (Profissional)

Domínios de atuação

Ciências Médicas e da Saúde - Biotecnologia Médica - Biotecnologia Aplicada à Saúde

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão	Peer-review
Inglês	Utilizador independente (B1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador independente (B1)	Utilizador independente (B1)
Espanhol; Castelhano	Utilizador elementar (A1)	Utilizador elementar (A1)	Utilizador elementar (A1)	Utilizador elementar (A1)	Utilizador elementar (A1)
Português (Idioma materno)

Formação

	Grau	Classificação
2021/10 - 2022/07/30 Concluído	Pedagogy for the Higher Education (Pós-Graduação) Universidade de Lisboa Instituto da Educação, Portugal	Approved
2009/10/01 - 2013/11/05 Concluído	Engenharia Química - Biotecnologia (Doutoramento) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Development of novel therapeutic approaches for wound healing in diabetes" (TESE/DISSERTAÇÃO)	Summa cum laude
2004 - 2008 Concluído	Bioquímica (Licenciatura) Universidade do Porto Faculdade de Ciências, Portugal "Effects of natural polyphenols in angiogenesis and inflammation" (TESE/DISSERTAÇÃO)	15

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2019/03/01 - Atual	Investigador Auxiliar (carreira) (Investigação)	Universidade de Lisboa Faculdade de Farmácia, Portugal

2014/12/01 - 2019/02/28	Pós-doutorado (Investigação)	Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
	Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/10/01 - 2016/12/30	Investigador visitante (Investigação)	Biomaterials Biodegradables and Biomimetics, Portugal
	Universidade do Minho, Portugal
2015/07/01 - 2016/06/30	Investigador visitante (Investigação)	University of Hertfordshire Department of Pharmacy, Reino Unido

Docência no Ensino Superior

	Categoria Profissional Instituição de acolhimento	Empregador
2018/02/01 - Atual	Assistente Estagiário (Docente Universitário)	Universidade de Lisboa Faculdade de Farmácia, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2023 - Atual	Guest Editor Pharmaceutics	Universidade de Lisboa Faculdade de Farmácia, Portugal

2014 - Atual	Laboratory Management	Universidade de Lisboa Faculdade de Farmácia, Portugal

2022/10 - 2023/05	Maternity Leave	Universidade de Lisboa Faculdade de Farmácia, Portugal

2019/10/01 - 2020/04/26	Maternity Leave	Universidade de Lisboa Faculdade de Farmácia, Portugal

2009 - 2013	Laboratory Management	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

2009/04/01 - 2009/09/30	Graduate Research fellow	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

2008/02/01 - 2008/10/31	Undergraduated training	Universidade do Porto Faculdade de Medicina, Portugal

Projetos

Bolsa

	Designação	Financiadores
2022 - 2025	Multifunctional nano-immunotherapy for melanoma brain metastases treatment PTDC/BTM-SAL/4350/2021 member of the Research Team	Fundação para a Ciência e a Tecnologia Em curso
2022/09/01 - 2024/03/31	Nano-immunotherapy to regulate immune profiling and microbiome in pancreatic cancer Exploratory Research Projects - 2022.04506.PTDC Investigador responsável	Fundação para a Ciência e a Tecnologia Em curso
2022/01/01 - 2023/06/30	Next-generation nanomaterials to sensitize breast cancer to immunotherapy UTAP-EXPL/NPN/0041/2021 Outra The University of Texas at Austin College of Pharmacy, Estados Unidos	Fundação para a Ciência e a Tecnologia Concluído
2020 - 2023	Instituto de Investigação do Medicamento UIDP/04138/2020 Outra	Em curso
2019/11 - 2020/11	HybExo-ALS - Engineering hybrid exosomes as microRNAs nanocarriers to microglia in Amyotrophic Lateral Sclerosis 100021-UID/DTP/04138/2019 Investigador responsável Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal	Universidade de Lisboa Instituto de Investigação do Medicamento Concluído
2013 - 2013	Promoting endothelial progenitor cell function in diabetic wound healing EFSD/JDRF Bolseiro de Doutoramento Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	European Foundation for the Study of Diabetes Concluído

Projeto

	Designação	Financiadores
2018 - Atual	MultiNano@MBM: Modulation of melanoma-stroma interactions using a rationally-designed nanomedicine combining BRAFi-, MEKi- and immune-therapies ENMed/0051/2016 Investigador Pós-doutorado Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2018 - Atual	POLYMMUNE: Off-the-Shelf Polypeptide-based Immunotherapy for Advanced Melanoma Treatment ERC-POC: SEP-210512889 Investigador Pós-doutorado Centro de Investigacion Principe Felipe, Espanha	European Research Council Concluído
2018 - Atual	Boronated Cytotoxic Multivalent Platforms - A New Concept to Fight Cancer PTDC/QUI-QOR/29967/2017 Investigador Pós-doutorado Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2023/03/12 - 2024/09/11	Nano-imunoterapia para regular o perfil imunológico e o microbioma no cancro pancreático 2022.04506.PTDC 10.54499/2022.04506.PTDC Fundación de la Comunidad Valenciana Centro de Investigación Príncipe Felipe, Espanha Universidade NOVA de Lisboa NOVA Medical School, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2020 - 2021	Nanomateriais para desenho de novas vacinas UTA-EXPL/NPN/0082/2019 10.54499/UTA-EXPL/NPN/0082/2019 Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2019/01/01 - 2019/12/31	Research Institute for Medicines UID/DTP/04138/2019 Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal Instituto Politécnico de Coimbra Centro de Estudos de Recursos Naturais Ambiente e Sociedade, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2015 - 2018	Multidisciplinary Strategy to Develop Novel Multicomponent Nanoscale Systems for Immune Modulation. UTAP-ICDT/DTP-FTO/0016/2014 Investigador Pós-doutorado	Fundação para a Ciência e a Tecnologia Concluído
2012/10/01 - 2014/11/30	Unlocking the research potential of 3Bs Group, University of Minho, in Nanomedicine field to strengthen its competitive position at the European level info:eu-repo/grantAgreement/EC/FP7/316331/EU Bolseiro de Pós-Doutoramento Biomaterials Biodegradables and Biomimetics, Portugal	European Commission Concluído
2013/06/01 - 2013/11	Anticipating diabetes and diabetic wounding for siblings of Type 2 diabetics. EXCL/DTP-PIC/0069/2012 Bolseiro de Doutoramento	Fundação para a Ciência e a Tecnologia
2013/01/01 - 2013	MECHANISMS AND TREATMENT STRATEGIES OF IMPAIRED WOUND HEALING IN DIABETES EXPL/BIM-MED/0492/2012 Bolseiro de Doutoramento Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2012 - 2013	Neuropeptide release in wounds: a new therapeutic approach for the treatment of diabetic foot ulceration PTDC/SAU-FAR/121109/2010 Bolseiro de Doutoramento Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2011/01/01 - 2012/12/31	Strategic Project - LA 1 - 2011-2012 PEst-C/SAU/LA0001/2011 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2009 - 2012	Dissecting the molecular mechanisms of wound healing in diabetes - the role of neuropeptides PTDC/SAU-MII/098567/2008 Bolseiro de Investigação Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluído

Produções

Publicações

Artigo em conferência	Carreira B; Acúrcio R; Pozzi S; Moura, Liane I F; Vaskovich D; Peres C; Fernandes A; et al. "Translational nanotechnology-based cancer vaccine to re-educate host immune response against metastatic cancers". Trabalho apresentado em Proceedings of the American Association for Cancer Research Annual Meeting 2023, 2023. 10.1158/1538-7445.AM2023-835 C Peres; AI Matos; Moura, Liane I F; B Carreira; M Verdial; J Conniot; MB Afonso; et al. Autor correspondente: H Florindo. "Multifunctional nanovaccine synergizes with OX40 agonist in triple-negative breast cancer". Trabalho apresentado em 46th FEBS Congress, 2022. Publicado • - Moura, LIF; Duro-Castano A; Peres C; Gallon E; Sainz V; Vicent MJ; Florindo H. "A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma". Trabalho apresentado em 25th Biennial Congress of the European Association for Cancer Research, 2018. Moura, L; Duro-Castano, A; Peres, C; Gallon, E; Matos, A; Vicent, MJ; Florindo, H. "PO-416 A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma". 2018. 10.1136/esmoopen-2018-eacr25.927 Moura, Liane I F; Martinho, N; Florindo, H; Zloh, M.. "Multifunctional poly (glutamic acid) dendrimer as delivery system of tumor associated antigens for cancer immunotherapy-a computational design approach". Trabalho apresentado em 42nd FEBS Congress, 2017, Jerusalem, 2017. Publicado Leal, EC; Pirzgalska, R; Marques da Silva, D; Moura, Liane I F; Espinoza, D; Ledent C; Koffalvi A; Carvalho, E.. "Early skin aging in diabetes is associated with a decrease in CB1 cannabinoid receptor expression". Trabalho apresentado em 53rd EASD Annual Meeting, 2017. Publicado Moura, Liane I F. "Early skin aging in diabetes is associated with a decrease in CB1 cannabinoid receptor expression". 2017. Moura, Liane I F; Martinho, N; Florindo, H; Zloh, M. "Computational design of a novel poly-glutamic dendrimer-based platform as an anticancer therapeutic approach". Trabalho apresentado em 41st FEBS Congress, 2016. Leal, EC; Pirzgalska, R; Marques da Silva, D; Moura, LIF; Espinoza, D; Ledent C; Koffalvi A; Carvalho, E.. "Diabetes Decreases CB1 Cannabinoid Receptor Expression Promoting Early Skin Aging". Trabalho apresentado em 75th Scientific Sessions of the American Diabetes Association, 2015. Carvalho, Lina; Moura, Liane I F; Ferreira Teresa; Aguiar MJ; Dinis A; Dias, Ana M. A.; Suesca, Edward; et al. "Collagen-based dressings loaded with neurotensin repair ulcers in diabetic mice". Trabalho apresentado em 24th European Congress of Pathology, 2013. Moura, Liane I F; Dias, AM; Suesca, E; Casadiegos, S.; Duque, MF; de Sousa, H.C.; Carvalho, Eugénia. "Neurotensin and collagen dressings improve diabetic wound healing". Trabalho apresentado em Annual Meeting of Portuguese Society of Diabetology, 2013, 2013. Pirgsgalska, R; Moura, Liane I F; Espinoza, D; Koffalvi, A; Leal, EC; Carvalho, Eugénia. "CB1 cannabinoid receptor can contribute to early skin aging in diabetes". Trabalho apresentado em Anual Meeting of Portuguese Society of Diabetology, 2013, 2013. Moura, Liane I F; Dias, AM; Suesca, E.; Casadiegos, S.; Duque MF; de Sousa, H.C.; Carvalho, E. "Neurotensin and collagen dressings improve diabetic wound healing". Trabalho apresentado em 48th EASD Annual Meeting, 2012. Carvalho, Lina; Moura, Liane I F; Dias, Ana M.A.; de Sousa, H.C.; Carvalho, Eugénia. "Neurotensin and Chitosan-based dressings repair ulcers of diabetic mice". Trabalho apresentado em European Conference of Pathology, 2012. Moura, Liane I F; Morgado, C; Pedro, JR; Lemos, C; Carvalho, Eugénia; Kofalvi, A. "Streptozotocin-induced type-1 diabetes triggers deregulation of cerebral glucose metabolism identical to genetic deletion of the CB1 cannabinoid receptor". Trabalho apresentado em 8th FENS Forum of Neuroscience 2012, 2012. Moura, Liane I F; Dias, AM; Leal, EC; de Sousa, HC; Carvalho, Eugénia. "Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment". Trabalho apresentado em 10º Congresso Português de Diabetes, 2012, 2012. Pedroso, D.C.S.; Tellechea, A.; Moura, L.; Fidalgo-Carvalho, I.; Duarte, J.; Carvalho, E.; Ferreira, L.. "Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells in a fibrin gel". 2011. Moura, Liane I F; Dias, AM; Leal, EC; de Sousa, H.C.; Carvalho, E.. "Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment". Trabalho apresentado em 47th EASD Annual Meeting, 2011, 2011. Leal, EC; Tellechea, A; Moura, Liane I F; Veves, A; Carvalho, E. "The role of neurotensin in wound healing in diabetic and iNOS knockout mice". Trabalho apresentado em 70th Scientific Sessions of the American Diabetes Association, 2010.
Artigo em revista	Matos, Ana I. I.; Peres, Carina; Carreira, Barbara; Moura, Liane I. F.; Acurcio, Rita C. C.; Vogel, Theresa; Wegener, Erik; et al. "Polyoxazoline-Based Nanovaccine Synergizes with Tumor-Associated Macrophage Targeting and Anti-PD-1 Immunotherapy against Solid Tumors". Advanced Science (2023): https://publons.com/wos-op/publon/55939439/. 10.1002/ADVS.202300299 Peres, C.; Matos, A. I.; Moura, L. I. F.; Carreira, B.; Verdial, M.; Conniot, J.; Afonso, M. B.; et al. "Multifunctional nanovaccine synergizes with OX40 agonist in triple-negative breast cancer". FEBS Open Bio (2022): https://publons.com/wos-op/publon/53912188/. C. Leal, Ermelindo; F. Moura, Liane I.; Pirzgalska, Roksana M.; Marques-da-Silva, Dorinda; Ledent, Catherine; Köfalvi, Attila; Carvalho, Eugenia. "Diabetes and Cannabinoid CB1 receptor deficiency promote similar early onset aging-like changes in the skin". Experimental Gerontology 154 (2021): 111528. http://dx.doi.org/10.1016/j.exger.2021.111528. 10.1016/j.exger.2021.111528 Peres, Carina; Matos, Ana I.; Moura, Liane I.F.; Acúrcio, Rita C.; Carreira, Barbara; Pozzi, Sabina; Vaskovich-Koubi, Daniella; et al. "Preclinical models and technologies to advance nanovaccine development". Advanced Drug Delivery Reviews 172 (2021): 148-182. http://dx.doi.org/10.1016/j.addr.2021.03.001. 10.1016/j.addr.2021.03.001 Pedro, Joana Reis; Moura, Liane I.F.; Valério-Fernandes, Ângela; Baptista, Filipa I.; Gaspar, Joana M.; Pinheiro, Bárbara S.; Lemos, Cristina; et al. "Transient gain of function of cannabinoid CB1 receptors in the control of frontocortical glucose consumption in a rat model of Type-1 diabetes". Brain Research Bulletin 161 (2020): 106-115. http://dx.doi.org/10.1016/j.brainresbull.2020.05.004. 10.1016/j.brainresbull.2020.05.004 Conniot, João; Scomparin, Anna; Peres, Carina; Yeini, Eilam; Pozzi, Sabina; Matos, Ana I.; Kleiner, Ron; et al. "Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators". Nature Nanotechnology 14 9 (2019): 891-901. http://dx.doi.org/10.1038/s41565-019-0512-0. 10.1038/s41565-019-0512-0 Matos, Ana I.; Carreira, Barbara; Peres, Carina; Moura, Liane I.F.; Conniot, João; Fourniols, Thibaut; Scomparin, Anna; et al. "Nanotechnology is an important strategy for combinational innovative chemo-immunotherapies against colorectal cancer". Journal of Controlled Release 307 (2019): 108-138. http://dx.doi.org/10.1016/j.jconrel.2019.06.017. 10.1016/j.jconrel.2019.06.017 Liane I.F. Moura; Cristina Lemos; Catherine Ledent; Eugénia Carvalho; Attila Köfalvi. "Chronic insulinopenia/hyperglycemia decreases cannabinoid CB1 receptor density and impairs glucose uptake in the mouse forebrain". Brain Research Bulletin 147 (2019): 101-109. https://doi.org/10.1016/j.brainresbull.2019.01.024. Publicado • 10.1016/j.brainresbull.2019.01.024 Liane I. F. Moura; Alessio Malfanti; Carina Peres; Ana I. Matos; Elise Guegain; Vanessa Sainz; Mire Zloh; María J. Vicent; Helena F. Florindo. "Functionalized branched polymers: promising immunomodulatory tools for the treatment of cancer and immune disorders". Materials Horizons 6 10 (2019): 1956-1975. https://doi.org/10.1039/C9MH00628A. Publicado • 10.1039/C9MH00628A Moura, Liane I F; Sains, V; Peres, C; Matos, AI; Viana, AS; Wagner, AM; Ramirez, JV; et al. "a-Galactosylceramide and peptide-based nano-vaccine synergistically induced a strong tumor suppressive effect in melanoma". Acta Biomaterialia 76 (2018): 193-207. Publicado • 10.1016/j.actbio.2018.06.029 Silva, Ana Luísa; Peres, Carina; Conniot, João; Matos, Ana I.; Moura, Liane; Carreira, Bárbara; Sainz, Vanessa; et al. "Nanoparticle impact on innate immune cell pattern-recognition receptors and inflammasomes activation". Seminars in Immunology 34 (2017): 3-24. http://dx.doi.org/10.1016/j.smim.2017.09.003. 10.1016/j.smim.2017.09.003 Moura, L. I. F.; Martinho, N.; Silva, L. C.; Barata, T. S.; Brocchini, S.; Florindo, H. F.; Zloh, M.; et al. "Poly-glutamic dendrimer-based conjugates for cancer vaccination – a computational design for targeted delivery of antigens". Journal of Drug Targeting 25 9-10 (2017): 873-880. http://dx.doi.org/10.1080/1061186x.2017.1363213. Publicado • 10.1080/1061186x.2017.1363213 Moura, L.; Martinho, N.; Florindo, H.; Zloh, M.. "Multifunctional poly (glutamic acid) dendrimer as delivery system of tumor associated antigens for cancer immunotherapy - a computational design approach". The FEBS Journal (2017): https://publons.com/wos-op/publon/10909664/. Leal, E. C.; Pirzgalska, R.; Marques-da-Silva, D.; Moura, L.; Espinoza, D.; Ledent, C.; Kofalvi, A.; Carvalho, E.. "Early skin aging in diabetes is associated with a decrease in CB1 cannabinoid receptor expression". Diabetologia (2017): https://publons.com/wos-op/publon/18569683/. Sainz, Vanessa; Conniot, João; Matos, Ana I.; Peres, Carina; Zupanoio, Eva; Moura, Liane; Silva, Liana C.; Florindo, Helena F.; Gaspar, Rogério S.. "Regulatory aspects on nanomedicines". Biochemical and Biophysical Research Communications 468 3 (2015): 504-510. http://dx.doi.org/10.1016/j.bbrc.2015.08.023. 10.1016/j.bbrc.2015.08.023 Moura, Liane I F; Dias, Ana M A; Suesca, Edward; Casadiegos, Sergio; Leal, Ermelindo C; Fontanilla, Marta R; Carvalho, Lina; et al. "Neurotensin-loaded collagen dressings reduce inflammation and improve wound healing in diabetic mice". Biochimica et Biophysica Acta - Molecular Basis of Disease 1842 1 (2014): 32-43. http://hdl.handle.net/10316/80404. 10.1016/j.bbadis.2013.10.009 Moura, L.I.; Cruz, M.T.; Carvalho, E.. "The effect of neurotensin in human keratinocytes - implication on impaired wound healing in diabetes". Experimental Biology and Medicine 239 1 (2014): 6-12. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891928865&partnerID=MN8TOARS. 10.1177/1535370213510665 Pereira da Silva, Lucília; Miguel Neves, Bruno; Moura, Liane; Cruz, Maria Teresa; Carvalho, Eugénia. "Neurotensin Decreases the Proinflammatory Status of Human Skin Fibroblasts and Increases Epidermal Growth Factor Expression". International Journal of Inflammation 2014 (2014): 1-9. http://dx.doi.org/10.1155/2014/248240. Publicado • 10.1155/2014/248240 Moura, L.I.F.; Dias, A.M.A.; Leal, E.C.; Carvalho, L.; De Sousa, H.C.; Carvalho, E.. "Chitosan-based dressings loaded with neurotensin - An efficient strategy to improve early diabetic wound healing". Acta Biomaterialia 10 2 (2014): 843-857. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896548394&partnerID=MN8TOARS. 10.1016/j.actbio.2013.09.040 Moura, Liane I F; Dias, Ana M A; Carvalho, Eugénia; de Sousa, Hermínio C; Moura, L.I.F.; Dias, A.M.A.; Carvalho, E.; De Sousa, H.C.. "Recent advances on the development of wound dressings for diabetic foot ulcer treatment--a review". Acta Biomaterialia 9 7 (2013): 7093-7114. http://hdl.handle.net/10316/80328. 10.1016/j.actbio.2013.03.033 Moura, Liane I. F.; Silva, Lucília; Leal, Ermelindo C.; Tellechea, Ana; Cruz, Maria Teresa; Carvalho, Eugénia. "Neurotensin Modulates the Migratory and Inflammatory Response of Macrophages under Hyperglycemic Conditions". BioMed Research International 2013 (2013): 1-13. http://dx.doi.org/10.1155/2013/941764. 10.1155/2013/941764 Carvalho, L.; Moura, L.; Ferreira, T.; d'Aguiar, M. J.; Dinis, A.; Suesca, E.; Casadiegas, S.; Fontanilla Duque, M.; de Sousa, H. C.. "Collagen-based dressings loaded with neurotensin repair ulcers in diabetic mice". Virchows Archiv (2013): https://publons.com/wos-op/publon/10403277/. Moura, L.; Dias, A.; Suesca, E.; Casadiegos, S.; Duque, M. F.; Sousa, H.; Carvalho, E.. "Neurotensin and collagen dressings improve diabetic wound healing". Diabetologia (2012): https://publons.com/wos-op/publon/5975838/. Carvalho, L.; Moura, L.; Dias, A.; Sousa, H.; Carvalho, E.. "Neurotensin and Chitosan-based dressings repair ulcers of diabetic mice". Virchows Archiv (2012): https://publons.com/wos-op/publon/10403276/. Pedroso, D.C.S.; Tellechea, A.; Moura, L.; Fidalgo-Carvalho, I.; Duarte, J.; Carvalho, E.; Ferreira, L.. "Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells". PLoS ONE 6 1 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-79551528768&partnerID=MN8TOARS. 10.1371/journal.pone.0016114 da Silva, L.; Moura, L.; Neves, B. M.; Cruz, M. T.; Carvalho, E.; Neves, B.M.; Cruz, M.T.. "Neurotensin downregulates the pro-inflammatory properties of skin-dendritic cells and increases epidermal growth factor expression". Diabetologia 1813 10 (2011): 1863-1871. https://publons.com/wos-op/publon/10403304/. 10.1016/j.bbamcr.2011.06.018 Moura, L.; Dias, A.; Leal, E.; Sousa, H.; Carvalho, E.. "Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment". Diabetologia (2011): https://publons.com/wos-op/publon/5975822/. Negrão, R.; Costa, R.; Duarte, D.; Taveira Gomes, T.; Mendanha, M.; Moura, L.; Vasques, L.; Azevedo, I.; Soares, R.. "Angiogenesis and inflammation signaling are targets of beer polyphenols on vascular cells". Journal of Cellular Biochemistry 111 5 (2010): 1270-1279. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649890064&partnerID=MN8TOARS. 10.1002/jcb.22850 Leal, Ermelindo; Tellechea, Ana; Moura, Liane; Veves, Aristidis; Carvalho, Eugenia. "The Role of Neurotensin in Wound Healing in Diabetic and iNOS Knockout Mice". Diabetes (2010): https://publons.com/wos-op/publon/6216558/. Negrao, Rita; Moura, Liane; Duarte, Delfim; Silva, Rafael; Soares, Raquel. "Modulation effect of catechin in angiogenesis and inflammation". The FASEB Journal (2009): https://publons.com/wos-op/publon/10403305/. Negrao, Rita; Moura, Liane; Soares, Raquel. "Establishing the molecular modulation of the inflammation by xanthohumol and its metabolites in endothelial and smooth muscle cells". The FASEB Journal (2009): https://publons.com/wos-op/publon/10403306/.
Capítulo de livro	Moura, Liane I F; Silva, Ana Luísa; Carreira, Barbara; Conniot, J; Matos, AI; Peres, C; Sainz, V.; et al. "Functional moieties for intracellular traffic of nanomaterials.". In Biomedical Applications of Functionalized Nanomaterials. Elsevier, 2018. Aceite para publicação
Poster em conferência	Ana I. Matos; Carina Peres; Bárbara Carreira; Moura, Liane I F; Rita C. Acúrcio; Ana S. Viana; Luís Graça; Ronit Satchi-Fainaro ; Helena F. Florindo. "Polyoxazoline Nanovaccine Synergizes with Tumor-Associated Macrophage Targeting and PD-1 blockade against Solid Tumors". Trabalho apresentado em XV Spanish-Portuguese Conference on Controlled Drug Delivery, 2024. R.C. Acúrcio; I. C. Sanchez; Moura, Liane I F; M. J. Vicent; R. Satchi-Fainaro ; H.F. Florindo. "From cold to hot: Nanotechnology-based immunotherapy driving effective PDAC anti-tumor response". Trabalho apresentado em XV Spanish-Portuguese Conference on Controlled Drug Delivery, 2024. Jéssica Cordeiro; Immaculada Conejos-Sánchez; Ana I Matos; Moura, Liane I F; María J. Vicent; Helena Florindo. Autor correspondente: Moura, Liane I F. "Combined nano-immunotherapy to regulate immune profiling and tumor-associated stroma in breast cancer". Trabalho apresentado em XV Spanish-Portuguese Conference on Controlled Drug Delivery, 2024. Silva M; Carreira B; Acúrcio R; Bonomo A; Matos AI; Moura LIF; Florindo HF. "Nano-immunotherapy for melanoma – a window of translation oncology". Trabalho apresentado em III ASPIC-ASEICA International Meeting, 2023. Cordeiro, Jéssica; CONEJOS-SANCHEZ, INMACULADA; Acúrcio, Rita C; Moura, Liane I F; María J. Vicente; Helena F Florindo. Autor correspondente: Moura, Liane I F. "Nano-immunotherapy to modulate immune cells in pancreatic cancer". Trabalho apresentado em "O Futuro Hoje: Novas Terapêuticas Moleculares e Biológicas¿, 2023. Carreira, Barbara; Acúrcio, Rita C; Pozzi, Sabina; Moura, Liane I F; Ana I. Matos; Kleiner, Ron; Vaskovich-Koubi, Daniella; et al. Autor correspondente: Helena F Florindo. "Translational nanotechnology-based cancer nanovaccine to re-educate host immune response against melanoma brain metastases". Trabalho apresentado em Gordon Research Conference on Cancer Nanotechnology and Gordon Research Seminar on Cancer Nanotechnology, 2023. Carreira, Bárbara; Rita Acúrcio; Sabina Pozzi; Moura, Liane I F; Peres, Carina; Fernandes, Adelaide; Xapelli Sara; Satchi-Fainaro, Ronit; Helena F Florindo. "Precision Nanomedicine-based Immunotherapy to Overcome Immunosuppression Against Metastatic Melanoma.". Trabalho apresentado em Champalimaud Research Symposium: Tumor Microenvironment (from cancer initiation to metastasis), 2022. Bento M; Mendes N; Moura, Liane I F; Wegener E; Jordan R, ; Conejos-Sánchez I; Vicent MJ,; Satchi-Fainaro R; Florindo HF. Autor correspondente: Florindo HF. "Multifunctional Nano-therapy to Overcome Pancreatic Cancer Immune Evasion". Trabalho apresentado em 13th iMed.ULisboa – Postgraduate Students Meeting, 2022. Peres C; Matos A; Moura, Liane I F; Carreira B; Graça L; Préat V; Satchi-Fainaro R; Florindo HF. "Targeted nanovaccine as a powerfull platform to improve immune modulation and checkpoint therapies in colorectal cancer". Trabalho apresentado em 28th Congress of the European Association for Cancer Research, 2022. Matos A; Peres C; Moura, Liane I F; Carreira B; Viana AS; Graça L; Satchi-Fainaro R; Florindo HF. "Multifunctional nanovaccine synergizes with OX40 agonist in triple-negative breast cancer". Trabalho apresentado em 28th Congress of the European Association for Cancer Research, 2022. Ana I. Matos; Peres, Carina; Moura, Liane I F; Carreira, Bárbara; Viana, A. S.; Graca, Luis; Satchi-Fainaro, Ronit; Helena F Florindo. "Targeted nanovaccine as a powerful platform to improve immune modulation and checkpoint therapies in colorectal cancer". Trabalho apresentado em EACR 2022 Congress - Innovative Cancer Science: Translating Biology to Medicine, 2022. Moura, LIF; Manfanti A; Vicent MJ; Florindo H. "Multivalent branched poly-l-glutamic acid-based nanovaccine sensitizes melanoma to anti-PD1 therapy". Trabalho apresentado em 13th International Symposium on Polymer Therapeutics: from Laboratory to Clinical Practice, 2022. Bento M; Moura, Liane I F; Florindo HF. "Multifunctional Polymeric Nanoplatform to Overcome Pancreatic Cancer Immune Evasion". Trabalho apresentado em 13th International Symposium on Polymer Therapeutics: from Laboratory to Clinical Practice, 2022. Moura, Liane I F; Florindo H. "Student centered teaching towards critical thinking in pharmaceutical technology". Trabalho apresentado em Jornadas Pedagógicas da Universidade de Lisboa - Ensino 4.0: Transição Digital, 2022. "Multivalent branched polypeptide-based nanovaccine as a novel immunotherapeutic approach for melanoma". Trabalho apresentado em LPCC_Cutaneous Melanoma: From Where to Where?, 2021. - "Precision Nanomedicine-based therapeutics to regulate immunosuppression against metastatic melanoma". Trabalho apresentado em Virtual iMed.ULisboa Meeting 2021, 2021. - "Multifunctional nanovaccine synergizes with OX-40 agonist in triple-negative breast cancer". Trabalho apresentado em EACR2021, 2021. - Carreira, Barbara; Acúrcio, Rita C; Pozzi, Sabina; Moura, Liane I F; Ana I. Matos; Satchi-Fainaro, Ronit; Helena F Florindo. Autor correspondente: Helena F Florindo. "Precision Multifunctional Nanomedicines to Regulate Immunosuppression Against Melanoma Brain Metastasis". Trabalho apresentado em Cutaneous Melanoma: From Where to Where?,, 2021. Ana I. Matos; Pena, Sandra; Mateus, Mariana; Carreira, Bárbara; Peres, Carina; Moura, Liane I F; Viana, Ana S. or Viana, Ana; et al. "Targeted nanovaccine as a powerful platform to improve immune modulation therapy in colorectal cancer". Trabalho apresentado em EACR-AACR-ASPIC Conference: Tumor Microenvironment, 2020. "Multifunctional nanovaccine synergizes with immune checkpoint therapy against triple-negative breast cancer". Trabalho apresentado em EACR-AACR Basic and Translational Research Conference in partnership with ASPIC Tumor Microenvironment, 2020. - "Targeted nanovaccine as a powerfull platform to improve immune modulation therapy in colorectal cancer". Trabalho apresentado em EACR-AACR Basic and Translational Research Conference in partnership with ASPIC Tumor Microenvironment, 2020. - "Functionalized nanobiomaterials as novel combination immunotherapies in cancer.". Trabalho apresentado em EACR-AACR-ASPIC Conference: Tumor Microenvironment, 2020. - Moura, Liane I F; Duro-Castano A; Malfanti A; Peres, C; Gallon E; Matos, AI; Benito AA; Vicent, MJ; Florindo, HF. "Multivalent polypeptide-based nanovaccine as anti-cancer immunotherapeutic strategy for melanoma". Trabalho apresentado em 17th Annual Meeting of the Association for Cancer Immunotherapy - CIMT, 2019. Aguiam N; Moura, Liane I F; Florindo, HF; Lopes JA. "Nanotechnology in medicine and challenges for the manufacturing of nanomedicines.". Trabalho apresentado em 14th Meeting of the Spanish Society of Pharmaceutics and Pharmaceutical Technology, 2019. Matos, AI; Carreira, Barbara; Moura, Liane I F; Peres, Carina; Viana, AS; Conde, JP; Graca, Luis; Satchi-Fainaro, Ronit; Helena F Florindo. Autor correspondente: Helena F Florindo. "Targeted nanovaccine as a powerfull platform to treat colorectal cancer.". Trabalho apresentado em EACR-AACR-ASPIC Conference: Nanotechnology in Cancer: Engineering for Oncology,, 2019. Moura, L; Duro-Castano, A; Peres, C; Gallon, E; Matos, A; Vicent, MJ; Florindo, H. "PO-416 A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma". Trabalho apresentado em 25th Biennial Congress of the European Association for Cancer Research., 2018. 10.1136/esmoopen-2018-eacr25.927 Peres, C; Matos, AI; Moura, Liane I F; Conniot, João; Carreira, Bárbara; Préat, V.; Satchi-Fainaro, R.; Florindo, H.F.; Graça, L. "Nanoparticle- based vaccine improved OX40 anti-tumor efficacy in breast cancer". Trabalho apresentado em 10th iMed.ULisboa Postgraduate Students Meeting & 3rd i3DU Meeting, 2018. Peres, Carina; Ana I. Matos; Moura, Liane I F; Conniot, João; Carreira, Bárbara; Viana, Ana S. or Viana, Ana; Graca, Luis; et al. "Nanoparticle-based vaccine improved the anti-tumor efficacy of the immune checkpoint co-stimulator OX40 in breast carcinoma". Trabalho apresentado em 10th iMed.ULisboa Postgraduate Students Meeting & 3rd i3DU Meeting, 2018. Florindo, H.F.; Peres, C; Conniot, J.; Moura, Liane I F; Matos, AI; Satchi-Fainaro, R.. "Polymeric nano-vaccines improved OX40 anti-tumor efficacy against breast cancer". Trabalho apresentado em Controlled Release Society Annual Meeting and Exposition., 2018. Moura, Liane I F; Duro-Castano, A; Peres, Carina; Gallon, Elena; Sainz, Vanessa; Ana I. Matos; Vicent, María J.; Helena F Florindo. "A novel multifunctional polypeptide-based platform as an immunotherapeutic approach for melanoma". Trabalho apresentado em Frontiers in Immunomodulation and Cancer Therapy, 2018. Matos, AI; Peres, C; Moura, L; Carreira, B; Viana, AS; Graça, L; Gaspar, R; Conde, JP; Florindo, HF. "PO-415 Multivalent polymeric nanoparticles as an innovative cancer immunotherapy for colorectal cancer". Trabalho apresentado em 25th Biennial Congress of the European Association for Cancer Research, 2018. 10.1136/esmoopen-2018-eacr25.926 Ana I. Matos; Peres, Carina; Moura, Liane I F; Carreira, Bárbara; Viana, Ana S. or Viana, Ana; Graca, Luis; Gaspar, Rogerio S; Conde, J.P.; Helena Florindo. "Multivalent polymeric nanoparticles as an innovative cancer immunotherapy for colorectal cancer". Trabalho apresentado em EACR25: From Fundamental Insight to Rational Cancer Treatment, 2018. Moura, Liane I F; Duro-Castano, A; Vicent, MJ; Florindo, HF. "A novel multifunctional polypeptide-based nanosystem as an anti-cancer immunotherapeutic approach for melanoma.". Trabalho apresentado em 12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice, 2018. Matos, AI; Moura, Liane I F; Conde, JP; Florindo, HF. "Multivalent polymeric nanoparticles for combinatorial innovative colorectal cancer immunotherapy and immunomodulation.". Trabalho apresentado em 16th CIMT Annual Meeting – Pushing Frontiers in Cancer Immunotherapy, 2018. Matos, AI; Peres, C; Moura, Liane I F; Conde, JP; Florindo, HF. "PLGA-based nanoparticles for combinatorial innovative colorectal cancer immunotherapy and immunomodulation.". Trabalho apresentado em 3rd ASPIC International Congress, 2018. Ana I. Matos; Peres, Carina; Moura, Liane I F; Carreira, Bárbara; Viana, Ana S. or Viana, Ana; Graca, Luis; Gaspar, Rogério; Conde, J.P.; Helena Florindo. "Multivalent PLGA-based nanoparticles for combinatorial innovative colorectal cancer immunotherapy and immunomodulation". Trabalho apresentado em 3rd ASPIC International Congress, 2018. Moura, Liane I F; Duro-Castano, A; Peres, C; Vicent, MJ; Florindo, H. F.. "Multifunctional polypeptide-based platform as an anti-cancer immunotherapeutic approach for melanoma.". Trabalho apresentado em XII Spanish-Portuguese Conference on Controlled Drug Delivery, 2018. Moura, Liane I F; Duro-Castano, A; Peres, C; Gallon E; Vicent, MJ; Florindo, HF. "A novel multifunctional polypeptide-based nanosystem as an anti-cancer immunotherapeutic approach for melanoma". Trabalho apresentado em Frontiers in Immunomodulation and Cancer Therapy, 2018. Moura, Liane I F; Martinho, N; Florindo, HF; Zloh, M. "Multifunctional poly (glutamic acid) dendrimer as delivery system of tumor associated antigens for cancer immunotherapy – a computational design approach". Trabalho apresentado em 42nd FEBS Conference, 2017. Peres, Carina; Moura, Liane I F; Ana I. Matos; Sainz, Vanessa; Viana, Ana S. or Viana, Ana; Gaspar, Rogério; Graca, Luis; Préat, Véronique; Helena F Florindo. "Polymeric nanoparticles as cancer vaccines and immunomodulators". Trabalho apresentado em 9th iMed.ULisboa Postgraduate Students Meeting & 2nd i3DU Meeting, 2017. Sainz, Vanessa; Peres, Carina; Moura, Liane I F; Ana I. Matos; Viana, Ana S. or Viana, Ana; Lopes, João; Gaspar, Maria Manuela; et al. "Hybrid Lipid-Polymeric Nanoparticles for the Treatment of Melanoma by Strengthening the Host Immune Response". Trabalho apresentado em 9th iMed.ULisboa Postgraduate Students Meeting & 2nd i3DU Meeting, 2017. Moura, Liane I F; Duro-Castano, A; Vicent, MJ. "A novel multifunctional star-shaped polypeptide-based platform as an anti-cancer immunotherapeutic approach". Trabalho apresentado em Gordon Research Conference “Cancer Nanotechnology - Multimodal Nano-Therapies Against Cancer”, 2017. Peres, Carina; Moura, Liane I F; Ana I. Matos; Sainz, Vanessa; Viana, Ana S. or Viana, Ana; Gaspar, Rogério; Graca, Luis; Préat, Véronique; Helena F Florindo. "Polymeric nanoparticles as breast cancer vaccines and immunomodulators". Trabalho apresentado em GRC Cancer Nanotechnology - Multimodal Nano-Therapies Against Cancer, 2017. Sainz, V.; Peres, C; Moura, Liane I F; Zloh, M; Florindo, HF. "A novel nanoplatform as metastatic melanoma cancer vaccine". Trabalho apresentado em 1st SPLC-CRS Young Scientist Meeting, 2017. Helena F Florindo; Zupancic, Eva; Peres, Carina; Sainz, Vanessa; Ana I. Matos; Moura, Liane I F; Curato, Caterina; et al. "Multicomponent Nanoscale Systems for Immune Modulation Against Solid Tumors.". Trabalho apresentado em Frontiers in Cancer Immunotherapy, 2017. Peres, Carina; Sainz, Vanessa; Ana I. Matos; Viana, Ana S. or Viana, Ana; Moura, Liane I F; Graca, Luis; Préat, Véronique; Helena F Florindo. "Multicomponent aliphatic polyester-based nanoparticles for antigen delivery and immune modulation against cancer disease". Trabalho apresentado em NanoBio&Med2016, 2016. Moura, Liane I F; Martinho, N; Florindo, H.F.; Zloh, M. "Computational design of a novel poly–glutamic dendrimer-based platform as an anticancer therapeutic approach". Trabalho apresentado em 41th FEBS Congress, 2016. Sainz, V.; Moura, Liane I F; Florindo HF. "Multicomponent nanoscale systems as metastatic melanoma therapeutic cancer vaccines". Trabalho apresentado em UT Austin\|Portugal Annual Conference, 2016. Moura, Liane I F; Aroso, I; Reis, RL; Pires, RA. "Cork extracts induce a cytoprotective effect against H2O2 oxidative damage in SH--SY5Y cells". Trabalho apresentado em IV ICVS/3B´S Meeting, 2014. Moura, Liane I F; Dias, AM; de Sousa, H.C.; Carvalho, E. "Neurotensin and collagen dressings improve diabetic wound healing". Trabalho apresentado em Annual Meeting of Portuguese Society of Diabetology, 2013. Pirsgalska, R; Moura, Liane I F; Espinoza, D; Leal, EC; Carvalho, E. "CB1 cannabinoid receptor can contribute to early skin aging in diabetes". Trabalho apresentado em CISE 2012 Conference, 2012. Moura, Liane I F; Dias, AM; de Sousa, H.C.; Carvalho, E. "Neurotensin and collagen dressings improve diabetic wound healing". Trabalho apresentado em 8th EASD Annual Meeting, 2012. Moura, Liane I F; Dias, AM; de Sousa, H.C.; Carvalho, E. "Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment". Trabalho apresentado em 47th EASD Annual Meeting, 2011. Moura, Liane I F; Soares Raquel; Negrão, Rita. "Effects of natural polyphenols on angiogenesis and inflammation". Trabalho apresentado em XVI National Congress of Biochemistry, 2008.
Resumo em conferência	Carreira, Bárbara; Acúrcio, Rita C; Pozzi, Sabina; Ron Kleiner; Moura, Liane I F; Ana I. Matos; Daniella Vaskovich-Koubi; et al. Autor correspondente: Ronit Satchi. "Abstract 835: Translational nanotechnology-based cancer vaccine to re-educate host immune response against metastatic cancers". Trabalho apresentado em AACR Annual Meeting 2023, Orlando, 2023. Publicado • 10.1158/1538-7445.AM2023-835
Tese / Dissertação	Moura, Liane. "Development of novel therapeutic approaches for wound healing in diabetes". Doutoramento, 2013. http://hdl.handle.net/10316/23741.

Propriedade Intelectual

Pedido provisório de patente

2019. "Cross-linked star-shaped self-assembled polypeptides as immunotherapies".
Protegido

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2024/02/15	Personalized neoantigen cancer nanovaccine to guide host immune response against melanoma brain metastases	XV Spanish-Portuguese Conference on Controlled Drug Delivery
2022/05/23	Multivalent branched poly-l-glutamic acid-based nanovaccine sensitizes melanoma to anti-PD1 therapy	13th International Symposium on Polymer Therapeutics: from Laboratory to Clinical Practice (Valencia, Espanha)
2022/05/23	Multifunctional Polymeric Nanoplatform to Overcome Pancreatic Cancer Immune Evasion	13th International Symposium on Polymer Therapeutics: from Laboratory to Clinical Practice (Valencia, Espanha)
2022/04/22	Multivalent polypetide-based nanovaccine as anti-cancer immunotherapeutic strategy for melanoma	International Conference on Pharmaceutics and Novel Drug Delivery Systems
2021/10/15	Precision Multifunctional Nanomedicines to regulate immunosuppression against melanoma brain metastasis	LPCC Cutaneous Melanoma: From Where to Where? (Portugal)
2021/03	Immuno-engineering: nanodelivery systems as tools for immune modulation in cancer	PhD Programme in Pharmacy - PhD Advanced Course in “Advanced Drug Delivery” (Portugal)
2021/01/21	Multivalent branched polypeptide-based nanovaccine as promising immunotherapeutic strategy for melanoma	3rd SPLC-CRS Young Scientists Virtual Meeting
2020/09/23	Nanotechnological approaches for immune modulation against solid cancers.	NanoPT 2020
2020/06/29	Nanovaccines as modulators of germinal center responses against cancer	CRS Virtual Meeting 2020
2019/09/12	Multi-targeting nano-based platform as an effective immunotherapy against solid tumors.	Nanotechnology in Cancer: Engineering for Oncology (Cambridge, Reino Unido)
2019/05/22	Multivalent polypeptide-based nanovaccine as anti-cancer immunotherapeutic strategy for melanoma	17th Annual Meeting of the Association for Cancer Immunotherapy - CIMT (Mainz, Alemanha)
2018/11/22	Polymeric nano-vaccines improved immune checkpoint anti-tumor efficacy against breast cancer	NanoBio&Med 2018 (Barcelona, Espanha)
2018/09/18	Polymer conjugates as cancer vaccines	FCT PhD Programme i3DU Course on “Advanced Drug Delivery” Universidade de Lisboa Faculdade de Farmácia (Portugal)
2018/05/28	A novel multifunctional polypeptide-based nanosystem as an anti-cancer immunotherapeutic approach for melanoma	12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice (Valencia, Espanha)
2017/11/24	Impact of multicomponent nano-vaccine on immune modulation against solid tumors	NanoBio&Med2017 (Barcelona, Espanha)
2017/09/14	Multifunctional poly (glutamic acid) dendrimer as delivery system of tumor associated antigens for cancer immunotherapy – a computational design approach	42nd FEBS Conference (Jerusalem, Israel)
2017/06/18	Insights on the Impact of Controlled Multicomponent Nanoscale Systems on Immune Modulation Against Solid Tumors	Gordon Research Conference “Cancer Nanotechnology - Multimodal Nano-Therapies Against Cancer” (Mount Snow, Estados Unidos)
2016/01/23	Melanoma cancer vaccine based on multifunctional nanoparticles for antigen delivery and immunomodulation	XI Spanish-Portuguese Conference on Controlled Drug Delivery; (Granada, Espanha)
2012/01/27	Neurotensin and chitosan-based dressings: a new approach for diabetic wound healing treatment	V SPB Clinical Biochemistry Workshop (Coimbra, Portugal)
2011/12/19	Neurotensin improves diabetic wound healing via inducible nitric oxide synthase	IX Annual Meeting of Center for Neuroscience and Cell Biology (Coimbra, Portugal)
2011/09/13	Neurotensin downregulates the pro-inflammatory properties of skin-dendritic cells and increases epidermal growth factor expression	47th EASD Annual Meeting (Lisbon, Portugal)
2010/03/10	Wound healing in diabetic and iNOS knockout mice: the role of Neurotensin	9º Congresso Português de Diabetes (Vilamoura, Portugal)
2010/01/28	Neurotensin improves wound healing in diabetic and iNOS knockout mice	IV SPB Clinical Biochemistry Workshop (Faro, Portugal)

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2024/01 - Atual	Modulation of tumor-immune microenvironment against cancer Coorientador	Ciências Farmacêuticas Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/01 - Atual	The Neuro-immune Axis in the Tumor Microenvironment Orientador	Ciências Farmacêuticas Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/01 - Atual	The impact of microbiome in immunotherapy for breast cancer Orientador	Ciências Farmacêuticas (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/01 - Atual	Collagen as a wound healing material Orientador	Ciências Farmacêuticas (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/01 - Atual	Sphingosomes: A modified Lipid nanoparticle platform for mRNA delivery Orientador	Ciências Farmacêuticas (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/10 - Atual	Nano-immunotherapy to regulate immune profiling and microbiome in pancreatic cancer Orientador
2022/09/01 - 2023	Recent nanotechnological approaches for immunotherapy in type 1 diabetes Orientador
2022/09/01 - 2022/12/15	Liposomal siRNA Formulation for the Treatment of rheumatoid arthritis Orientador
2022/02/01 - 2022/06	Cyclodextrins associated to polymeric nanovaccines for immune cell targeting Coorientador
2022/02/01 - 2022/06	Cyclodextrins associated nanocarriers for immune modulation. Coorientador
2022/02/01 - 2022/06	Nanovaccines for immune modulation in pancreatic cancer Coorientador	Univerza v Ljubljani, Eslovénia
2021/09/01 - 2022	Impact of microbiome in cancer nano-immunotherapy Orientador
2021/09/01 - 2022	PLGA in situ forming microparticles loaded with nanosized dexamethasone as long-term drug delivery carriers Orientador
2020/09/01 - 2021/12	Combination of a multifunctional nanovaccine with modulators of pancreatic cancer microenvironment Coorientador	M.Sc. in BioPharmaceutical Sciences (FFUL) (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/01 - 2021/04	Nanovaccines for immune modulation in pancreatic cancer Coorientador
2021 - 2021	Recent nanotechnological approaches for immunotherapy in type 1 diabetes Orientador	Master Thesis in Pharmaceutical Sciences at FFUL (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 - 2021	Impact of microbiome in cancer nano-immunotherapy Orientador	Master Thesis in Pharmaceutical Sciences at FFUL (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 - 2021	Detection of mannose moieties on the surface of nanoparticle-based immunotherapy Coorientador	Biologia Celular e Molecular (Licenciatura/Bacharelato) Universidade Nova de Lisboa, Portugal
2020 - 2021	Development of PCL-based nanovaccine for DC-targeting Orientador
2020 - 2021	PCL-based nanovaccines for pancreatic cancer Coorientador
2019/10 - 2020/09	Nanoplatform to modulate dendritic cells and tumor microenvironment against Triple negative breast cancer Coorientador	Master Thesis in Biopharmaceutical Sciences (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/02 - 2019/12	Nanovaccines as tumor microenvironment modulators Coorientador	Thesis (2nd semester) in Pharmaceutical Sciences(FFUL) (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/10 - 2019/12	Multi-functional nanovaccine modulates dendritic cell effector function against melanoma Coorientador	Master Thesis in Biopharmaceutical Sciences (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/10 - 2019/12	Impact of the modulation of tumor vasculature on cancer vaccine efficacy against colorectal cancer Coorientador	Master Thesis in Biopharmaceutical Sciences (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/02 - 2019/07	Development of polysaccharide-based biodegradable nanovaccines for dendritic cell targeting Coorientador	Project II (2nd semester) Pharmaceutical Sciences(FFUL) (Outra) Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/09 - 2019/02	Optimization of Dendritic Cell- targeting nanovaccines Coorientador	Project III (1st semester) Pharmaceutical Sciences(FFUL) (Outra) Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/09 - 2019/02	Optimization of polymeric based-nanovaccines for dendritic cell targeting Coorientador	Project I (1st semester) Pharmaceutical Sciences(FFUL) (Outra) Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/09 - 2018/02	Combination of ß-glucan and mannose as immunomodulators in a multicomponent nanoscale therapeutic cancer vaccine Coorientador	Project I (1st semester) Pharmaceutical Sciences(FFUL) (Outra) Universidade de Lisboa Faculdade de Farmácia, Portugal

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2019/01/23 - 2019/01/23	2nd SPLC-CRS Young Scientist Meeting (2019/01/23 - 2019/01/23) Conferência (Membro da Comissão Científica)
2012/12/19 - 2012/12/19	IX Annual Meeting of Center for Neuroscience and Cell Biology (2012 - 2012) Encontro (Membro da Comissão Organizadora)

Participação em evento

	Descrição da atividade Tipo de evento	Nome do evento Instituição / Organização
2018/07/10 - 2018/07/12	Training School “Behavioural Phenotyping in mice: Focus on longitudinal studies in ageing”, Madrid, Spain Oficina (workshop)
2017/10/04 - 2017/10/06	Training School “Drug Discovery and Development”, Novartis Campus, Basel, Switzerland Oficina (workshop)
2017/01/17 - 2017/01/19	Training School “Introduction to Mathematical and Computational Modelling: from mouse to computer and back”, Eindhoven, Netherlands Oficina (workshop)
2011/11/14 - 2011/11/18	Course of “International de la Red Iberoamericana de Nuevos Materiales para el Diseño de Sistemas Avanzados de Liberación de Fármacos en Enfermedades de Alto Impacto Socioeconómico (RIMADEL)”, Santiago de Compostela, Spain Oficina (workshop)
2011/02/28 - 2011/03/04	Course of “Fluorescence/ Confocal Microscopy and Flow Cytometry – An integrative approach to cell analysis”, Braga, Portugal Oficina (workshop)
2010/04/19 - 2010/04/30	Course of “Laboratory Animal Science - Category C”, accredited by FELASA, Coimbra, Portugal
2009/03/09 - 2009/03/13	Course of “Obesity and Type II Diabetes”, Coimbra, Portugal

Júri de grau académico

	Tema Tipo de participação	Nome do candidato (Tipo de grau) Instituição / Organização
2023/12/15	Characterization of breast cancer immunity Arguente	Raquel Ventura Rebordão Gouveia (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/12	Alginate Rubber Mask as a Double Friend: Cosmetic and Skin Barrier Protector Arguente principal	Maria Rita Ramos Curva (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/11/20	Formulation and characterization of drug-loaded PLGA nanoparticles Imaging capabilities of Raman-bas Arguente principal	Teresa Ramires Ruas (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/11/15	Formulações Lipossomais de Glucocorticóides para o tratamento da Artrite Reumatóide: Preparação, caracterização e avaliação in vitro. Arguente principal	Tatiana Filipa Rebelo Pereira (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/11/18	Evaluation of neuron/glia network signals using 2D/3D platforms and ALS experimental models Arguente	Beatriz da Cunha Suyumov (Mestrado)
2022/11/16	Investigation of a correlation between the stability of polymeric NPs towards temperature and gene knockdown efficiency Arguente principal	Daniela Azedo (Mestrado)
2022/07/22	Pancreatic Ductal Adenocarcinoma (PDAC): Modulation of Cathepsin S Arguente	Ana Marta Reinold´s Nunes (Outro)

Arbitragem científica em conferência

	Nome da conferência	Local da conferência
2018/09 - 2020/08	SPLC-CRS Young Scientist Meeting

Arbitragem científica em revista

	Nome da revista (ISSN)	Editora
2021 - Atual	Pharmaceutics

Comissão de avaliação

	Descrição da atividade Tipo de assessoria	Instituição / Organização	Entidade financiadora
2021 - Atual	COST Association External Reviewer Avaliador

Membro de associação

	Nome da associação	Tipo de participação
2018 - Atual	Association for Cancer Immunotherapy (CIMT)
2016 - Atual	European Association for Cancer Research (EACR)
2016 - Atual	Portuguese Association for Cancer Research (ASPIC)
2015 - Atual	The Spanish Portuguese Local Chapter of the Controlled Release Society (SPLC-CRS)
2015 - Atual	Portuguese Society of Biochemistry (SPB)
2015 - Atual	Federation of European Biochemical Societies (FEBS)
2012 - 2013	Grupo de Investigação Fundamental e Translacional (GIFT)
2012 - 2013	Grupo de Estudos de Pé Diabético em Portugal (GREPED)
2009 - 2013	Portuguese Society of Diabetology (SPD)
2009 - 2013	European Association for the Study of Diabetes (EASD)

Outro júri / avaliação

	Descrição da atividade	Instituição / Organização
2023/08 - Atual	President of the Jury - call for the award of 1 (One) Master Research Grant within the scope of the project 2022.04506.PTDC, titled “Nano-imunoterapia para regular o perfil imunológico e o microbioma no cancro pancreático Reference: BICNCG/14/FARM-ID/2023	Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 - 2019	Jury of undergraduated student research project - Project II (2nd semester) Pharmaceutical Sciences(FFUL)	Universidade de Lisboa Faculdade de Farmácia, Portugal

Revisão ad hoc de artigos em revista

	Nome da revista (ISSN)	Editora
2024 - Atual	Genes
2024 - Atual	Cells
2022 - Atual	Viruses
2021 - Atual	Materials Today Bio
2021 - Atual	Vaccines
2020 - Atual	DDTR
2020 - Atual	Pharmaceutics

Tutoria

	Tópico	Nome do aluno
2023/07/01 - 2023/07/06	OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2023 – programa Ciência Viva no Laboratório CRIAR FUTURO	Célia Borges
2023/07 - 2023/07	OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2023 – programa Ciência Viva no Laboratório CRIAR FUTURO -Project “De nanopartículas a uma vacina para o cancro”	Katarina Coelho
2023/07 - 2023/07	OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2023 – programa Ciência Viva no Laboratório CRIAR FUTURO -Project “De nanopartículas a uma vacina para o cancro”	Luana Favaro
2022/06/27 - 2022/07/01	OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2022 – programa Ciência Viva no Laboratório	Letícia Soares Barcelos
2022/06/27 - 2022/07/01	OCUPAÇÃO CIENTÍFICA DE JOVENS NAS FÉRIAS 2022 – programa Ciência Viva no Laboratório	João Carneiro
2011/02 - 2012/02	A cicatrização de feridas está comprometida durante a fase inicial de cura em ratinhos Balb/c/Rag2-/-IL2R-/-	Jenifer Gonçalves
2010/09 - 2011/04	Role of neurotensin in diabetic wound healing	Valentina Maio
2009/10 - 2010/07	Neurotensin effect on skin dendritic cells and fibroblasts: repercussions in wound healing and diabetic wound healing	Lucilia Pereira da Silva

Distinções

Prémio

2022	ERASMUS + - mobility grant, for 13th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice
2011	Bolsa Dr. M. M. Almeida Ruas - S.P.D. / Novo Nordisk - "Promoting endothelial progenitor cell function in diabetic wound healing" Sociedade Portuguesa de Diabetologia, Portugal

Outra distinção

2020	Topic Editor - Journal Pharmaceutics
2019	Travel Grant fellowship for 17th CIMT Annual Meeting; Mainz, Germany, 21st – 23rd May 2019
2018	Grant by Cost Action for Training School “Behavioural Phenotyping in mice: Focus on longitudinal studies in ageing”, Madrid, Spain, 10th-12th July 2018
2018	Travel Grant fellowship for 12th International Symposium on Polymer Therapeutics: From Laboratory to Clinical Practice. Valencia, Spain; 28th-30th May 2018
2017	Grant by Cost Action for Training School “Drug Discovery and Development”, Novartis Campus, Basel, Switzerland, 4th-6th October 2017
2017	FEBS Bursary for 42nd FEBS Congress; Jerusalem, 10-14 September 2017
2017	Grant by Cost Action for Training School “Introduction to Mathematical and Computational Modelling: from mouse to computer and back”; Eindhoven, Netherlands, 17th-19th January 2017
2016	Travel Grant fellowship for 16th YSF and 41st FEBS Congress; Kusadasi, Turkey; 30 August - 9 September 2016
2014	Post-Doctoral fellowship reference SFRH/BPD/94111/2013 from the Portuguese Foundation for Science and Technology (FCT) Fundação para a Ciência e a Tecnologia, Portugal
2014	Post-Doctoral fellowship funded by the European project Ref: REGPOT-CT2012-316331-POLARIS Biomaterials Biodegradables and Biomimetics, Portugal
2012	Travel grant fellowship for 48th EASD Annual Meeting; Berlim; Germany; 1st-5th October 2012
2009	PhD Fellowship reference SFRH/BD/60837/2009 from the Portuguese Foundation for Science and Technology (FCT) Fundação para a Ciência e a Tecnologia, Portugal
2009	Graduate Research fellowship funded by the FCT project Ref: POCI/SAU-MMO/57598/2004 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008	Grant by IBeSa to attend XVI National Congress of Biochemistry, Ponta Delgada, Portugal, 22th – 25th October 2008