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Lino Ferreira (LF) is an Investigator Coordinator (equivalent to Full Professor) at the Faculty of Medicine, University of Coimbra, and a senior researcher at the Associate Laboratory Center for Innovation in Biomedicine and Biotechnology (CIBB) at the same University. His academic background combines biomaterials and stem cell biology, providing a strong interdisciplinary foundation for research at the interface of ageing and regenerative medicine. Throughout his career, he has developed and led innovative research programs focused on human in vitro disease models, extracellular vesicles, nano- and biomaterial-based therapeutic platforms, and mechanisms of ageing and regeneration. Since the beginning of his career he gathered more than 17500 citations by peers, endowing him an h-index of 66. LF is the inventor of more than 25 international patents, 10 of which have been licensed to companies. LF was also involved in the design of the first researcher-driven clinical trial with human cells in Portugal. Beyond research, LF has a strong record of leadership and service to the scientific community. He served as President of the Portuguese Society of Stem Cells and Cell Therapies (2013–2015) and currently holds governance roles within several entities at the University of Coimbra, including membership on the Board of the Center for Neuroscience and Cell Biology (CNC) and the Board of CIBB. He served as a member of the Scientific Councils of the Organic Unit 3Is (2020-2023) and the Faculty of Medicine (2019-2023). Since 2021, he is the coordinator of the collaborative laboratory called Colab4Ageing that joins several stakeholders in the chain value, to develop, test and implement innovative products and services in the area of ageing. Since 2019 until now, he is associate editor of the journal Biomaterials Science. He has been actively involved since their inception in two scientific societies: the Portuguese Society of Stem Cells and Cell-Based Therapies and the Portuguese Network on Extracellular Vesicles. He is actively involved in graduate and postgraduate teaching, contributing to courses and supervision in biomedical sciences, regenerative medicine, and advanced therapies. LF has been the primary supervisor of 20 postdoctoral researchers, six of whom have obtained principal investigator (PI) positions. He has also served as the primary supervisor of 24 PhD students and co-supervisor of 7 additional PhD students, all of whom successfully defended their theses. In addition, LF has been the primary supervisor or co-supervisor of 24 MSc students who successfully defended their theses. Members of LF’s research group have founded several companies (e.g., Matera, Curemat, Tissium, Exogenus Therapeutics, and DoDoc), collectively attracting more than €150 million in venture capital. LF has secured substantial competitive funding at national and international levels. In the last 10 years, he attracted more than 15 million euros of competitive funding including 1 ERA Chair project, 1 Twinning project, 1 Marie Curie ITN project, 5 Marie Curie International fellowships, 2 pathfinder open projects, 5 Horizon European projects, as well as several FCT and industry projects. In the last 5 years, he has: (i) published more than 65 articles in international peer-reviewed journals, (ii) disseminated his work in more than 50 international conferences and (iii) acted as co-chair of 6 symposia in high profile conferences (TERMIS, ESB, ESCI). He was the recipient of several awards/prizes including the Portuguese Society of Stem Cell Therapies (2022), Bluepharma innovation (2016), FCT Investigation (2013 and 2015) and the Crioestaminal prizes (2008).
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Identificação

Identificação pessoal

Nome completo
Lino Ferreira

Nomes de citação

  • Ferreira, Lino

Identificadores de autor

Ciência ID
7213-B63A-ECA6
ORCID iD
0000-0001-8985-9302
Google Scholar ID
https://scholar.google.com/citations?user=WNUIcigAAAAJ&hl=pt-PT

Moradas

  • Faculty of Medicine Pólo das Ciências da Saúde, Unidade Central Azinhaga de Santa Comba, 3000-354, Coimbra, Coimbra, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Engenharia Médica - Engenharia Médica
  • Ciências da Engenharia e Tecnologias - Nanotecnologia
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
  • Ciências Médicas e da Saúde - Biotecnologia Médica - Diagnóstico e Terapias de Base Genética

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Formação
Grau Classificação
1999/09/01 - 2003/11/24
Concluído
 PhD in Chemical Engineering (Doutoramento)
Especialização em Biotecnologia- PhD degree performed in a sandwich program between Rensselaer Polytechnic Institute (New York, USA) and University of Coimbra (Portugal)
Universidade de Coimbra, Portugal
 Distinção e Louvor
1995/09/01 - 1998/03/06
Concluído
 MSc in Biochemistry (Mestrado)
Universidade de Coimbra Departamento de Ciências da Terra, Portugal
"Enzymatic modification of sacharides" (TESE/DISSERTAÇÃO)
 Very Good
1989/09/01 - 1994/07/20
Concluído
 BSc in Biochemistry (Licenciatura)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
 Good
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2021/05/01 - Atual Investigador Coordenador (carreira) (Investigação) Universidade de Coimbra, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
2016/11/01 - 2021/04/30 Investigador Coordenador Convidado (carreira) (Investigação) Universidade de Coimbra Faculdade de Medicina, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
2015/05/01 - 2016/11/01 Investigador Coordenador (carreira) (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/01/01 - 2015/05/01 Investigador principal (carreira) (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2007/09/01 - 2012/12/31 Investigador Auxiliar (carreira) (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2004/09/01 - 2007/08/31 Pós-doutorado (Investigação) Massachusetts Institute of Technology, Estados Unidos
2003/09/01 - 2004/08/31 Pós-doutorado (Investigação) Instituto Nacional de Engenharia Biomédica, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2001/09/01 - 2002/03/31 Assistente convidado (Docente Ensino Superior Politécnico) Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2021/12/12 - Atual Presidente Colab4Ageing, Portugal
Colab4Ageing, Portugal
2019/06/01 - Atual Member of Centro de Neurociências e Biologia Celular Board Universidade de Coimbra, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2022/01/19 - 2022/12/11 Colab4Ageing- Member of Installation Committee Universidade de Coimbra, Portugal
2010/12/01 - 2010/12/31 Invited Professor Université d'Artois Bibliothèque de Lens, França

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2018/02/01 - Atual Coordinator of one of the three thematic strands ("Innovation Therapies") of the research center CIBB Universidade de Coimbra, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/01/01 - Atual Head of the laboratory Advanced Therapies at CNC Universidade de Coimbra, Portugal
2019/05/01 - 2023/07/31 Member of the Scientific Counsel of Medicine Faculty Universidade de Coimbra, Portugal
Universidade de Coimbra Faculdade de Medicina, Portugal
2020/09/01 - 2023/02/22 Member of the Scientific Counsel of 3Is Universidade de Coimbra, Portugal
2009/01/01 - 2022/09/30 Founder of Matera, a biomaterial-based company Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2007/09/01 - 2018/07/31 CNC coordinator of MIT-Portugal Program, focus in bioengineering Universidade de Coimbra, Portugal
2015/01/01 - 2018/01/01 Coordinator of the group Therapy 2 –Stem cell biotechnology, Strategic project of the consortium CNC.IBILI (Ref: UID/NEU/04539/2013), funded by Fundação para a Ciência e a Tecnologia Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/06/01 - 2015/10/01 President of the Portuguese Society of Stem Cells and Cell Therapies Universidade de Coimbra, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009/01/01 - 2010/12/31 Member of the Board of Directors of the Portuguese Society of Stem Cells and Cell Therapies Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2007/01/01 - 2008/12/31 Member of the General Assembly of the Portuguese Society of Stem Cells and Cell Therapies Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
1999/01/01 - 2003/08/31 PhD fellow at Chemical Engineering department, University of Coimbra Fundação para a Ciência e a Tecnologia, Portugal
1995/09/01 - 1997/08/31 Msc fellow at Biochemistry department of University of Coimbra Fundação para a Ciência e a Tecnologia, Portugal
Projetos

Bolsa

Designação Financiadores
2023/01/01 - 2026/12/31 Piezo-driven theramesh: A revolutionary multifaceted actuator to repair the injured spinal cord
101098597
Investigador responsável
Horizon 2020
Em curso
2023/01/01 - 2026/12/31 REMODELLING OF THE INFARCTED HEART: PIEZOELECTRIC MULTIFUNCTIONAL PATCH ENABLING THE SEQUENTIAL RELEASE OF THERAPEUTIC FACTORS
101091852
Investigador responsável
Horizon 2020
Em curso
2025/02/20 - 2026/08/19 A nanotherapeutic strategy to tackle vascular cell senescence
2023.12423.PEX
10.54499/2023.12423.PEX
Universidade de Coimbra, Portugal

Institut d'Investigacions Biomèdiques August Pi i Sunyer, Espanha
Fundação para a Ciência e a Tecnologia
Em curso
2023/01/01 - 2025/12/31 Heat-induced epithelial permeability: a nanoscale-based solution for the treatment of fungal keratitis
na
Centro Hospitalar e Universitário de Coimbra EPE, Portugal
 Centro Hospitalar e Universitário de Coimbra EPE
Em curso
2023/03/01 - 2025/02/28 Targeted senolytic delivery system to treat liver cirrhosis
2022.02783.PTDC
10.54499/2022.02783.PTDC
Universidade de Coimbra, Portugal

Institut d'Investigacions Biomèdiques August Pi i Sunyer, Espanha
Fundação para a Ciência e a Tecnologia
Concluído
2021/03/01 - 2024/08/31 A therapeutic strategy to fight blood-brain-barrier (BBB) ageing
PTDC/BTM-SAL/5174/2020
10.54499/PTDC/BTM-SAL/5174/2020
Universidade de Coimbra, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2021/01/01 - 2023/12/31 RESETAgeing
952266
Universidade de Coimbra, Portugal
 European Commission
Concluído
2020/11/01 - 2022/10/31 COVIRNA: a diagnostic test to improve surveillance and care of COVID-19 patients
101016072
Investigador responsável
European Commission
2018/06/01 - 2022/05/31 NANOSTEM: new nanomaterials for neural stem cells drug delivery
721468
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 European Commission
Em curso
2020/05/01 - 2022/04/30 LIGHTEST: LIght-responsive GrapHene-based inTerfaces for Electrical Stimulation
101003413
Investigador responsável
European Commission
2018/07/01 - 2022/03/30 An iPSC-derived vascular model of Progeria to identify mediators for smooth muscle loss
029229
Investigador responsável
Fundação para a Ciência e a Tecnologia
2017/08/01 - 2021/03/01 Towards personalized beta-cell mass imaging in type 2 Diabetes
40-41200-98-9307
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 ZonMw
Em curso
2017/01/01 - 2020/12/31 Tackling CANcer STEM CELls: a challenge and an opportunity to advance in anti-cancer therapy
POCI-01-0145-FEDER-016390
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2016/12/01 - 2020/12/31 NETDIAMOND: new targets in diastolic heart failure, from comorbidities to personalized medicine
10.3030/952266
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2015/07/01 - 2020/12/31 ERA at UC: Enhancing Research in Ageing at the University of Coimbra
669088
Investigador responsável
Universidade de Coimbra, Portugal
 EU Framework Programme for Research and Innovation Spreading Excellence and Widening Participation
Em curso
2016/03/01 - 2020/03/01 StrokeTherapy: Plataformas terapêuticas para acidentes vasculares cerebrais
POCI-01-0247-FEDER-003386
Investigador responsável
Universidade de Coimbra, Portugal
Concluído
2016/07/01 - 2019/12/31 Unraveling the Rules of Passive Permeation Through the Blood-Brain Barrier
PTDC/DTP-FTO/2784/2014
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2017/04/01 - 2019/03/31 TRoMBONE: Therapy for regeneration of Heart Muscle based on targeted delivery of exosomes
748583
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 European Commission
Concluído
2014/12/01 - 2017/11/30 CARDIOSTEM- Engineered cardiac tissues and stem cell-based therapies for cardiovascular applications
MITP-TB/ECE/0013/2013
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2012/11/01 - 2017/10/31 Triggerable nanomaterials to modulate cell activity
info:eu-repo/grantAgreement/EC/FP7/307384/EU
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 European Research Council
Concluído
2015/02/18 - 2017/02/17 Inducing hemogenesis: mechanisms underlying hemogenic induction in human fibroblasts
628761
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 European Commission
Concluído
2014/01/01 - 2016/12/31 Innovative antifouling materials for maritime applications
FP7_OCEAN-2013.3
Investigador responsável
Biocant Associação de Transferência de Tecnologia, Portugal
Concluído
2013/07/01 - 2016/06/30 Combinatorial approaches to promote cell survival - PROSURVIVAL
info:eu-repo/grantAgreement/FCT/COMPETE/125994/PT
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2012/07/01 - 2016/06/30 NANODRUG - NOVEL NANOPARTICLES FOR DRUG DELIVERY TO THE SKIN
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBI2%F519042%F2012/PT
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 European Commission
Concluído
2012/05/01 - 2016/04/30 Modulation of hematopoietic stem cell (HSC) activity by transcription factor-releasing nanoparticles- STEMCELLMODULATORS
info:eu-repo/grantAgreement/FCT/COMPETE/120552/PT
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2012/03/01 - 2016/02/29 Modulation of induced pluripotent stem cells differentiation by carbon nanotube templates - StemCelCan
info:eu-repo/grantAgreement/FCT/COMPETE/119184/PT
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2012/01/01 - 2015/12/31 PERSONALIZED 3D VASCULAR CONSTRUCTS FOR TOXICITY ASSESSMENT- VASCTOX
PTDC/SAU-TOX/121887/2010
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2014/03/01 - 2015/05/31 To unravel the vulnerability of Progeria smooth muscle cells- Smooth_Progeria
info:eu-repo/grantAgreement/FCT/COMPETE/135292/PT
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2011/01/01 - 2014/12/31 Generation of hematopoietic-compartment-derived Induced Pluripotent Stem cells using a non-viral approach and their differentiation into cardiomyocytes- iPSCardio
PTDC/SAU-ENB/113696/2009
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2013/07/01 - 2014/09/30 Human cardiac engineered tissue for toxicity assessment- CARDIOTOX
info:eu-repo/grantAgreement/FCT/COMPETE/126384/PT
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2010/09/01 - 2013/12/31 Heart regeneration by embryonic vascular cells and a biomimetic scaffold
PTDC/SAU-BEB/098468/2008
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2010/01/01 - 2013/12/31 Nanomaterials for cell tracking
PTDC/CTM/099659/2008
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2010/01/01 - 2013/12/31 Antimicrobial coatings- Killmicrob
PTDC/ Qui-Qui / 105000 / 2008
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2010/01/01 - 2013/12/31 HISTAMINE VERSUS ANTIHISTAMINES: NEW MODULATORS OF NEUROGENESIS?
PTDC/SAU-NEU/104415/2008
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2009/01/01 - 2013/12/31 Heart regeneration
PIRG03-GA-2008-230929
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 European Commission
Concluído

Projeto

Designação Financiadores
2022/01/01 - 2023/12/31 A gene-editing nanoparticle formulation for retinal degeneration diseases
EXPL/BIA-CEL/0989/2021
10.54499/EXPL/BIA-CEL/0989/2021
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal

Universidade de Coimbra, Portugal

Universidade Nova de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2021 - 2023/06/30 New imaging biomarkers in the assessment of chronic total coronary occlusion (Novos biomarcadores de imagem na avaliação das oclusões coronárias crónicas totais)
BioImage2CTO - 39698
Universidade de Coimbra, Portugal

Universidade do Minho Centro de Química, Portugal

Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal
Agência Nacional de Inovação SA
Concluído
2018/06/22 - 2022/06/21 A novel mechanism to re-pair Heart Failure with preserved Ejection Fraction (HFpEF) and endothelial damage
PTDC/MED-PAT/32179/2017
Universidade de Coimbra, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2018/06/22 - 2021/06/21 BrainEdition: controlo remoto da edição genética em células estaminais neurais
PTDC/NAN-MAT/28060/2017
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2017/01/01 - 2021/03/31 Estaminalidade das células do cancro: um desafio e uma oportunidade para avançar no tratamento em Oncologia
SAICTPAC/0022/2015
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra, Portugal

Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal

Fundação Calouste Gulbenkian, Portugal

Instituto de Engenharia Biomédica, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2014/01/01 - 2015/12/31 Exocord – Exosomas de células estaminais e seus derivados para tratamento de feridas crónicas em pacientes diabéticos
FCOMP-01-0202-FEDER-038631
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Concluído
2010/01/01 - 2013/12/31 Antimicrobial coatings and materials based in polycationic polymers
IAMPMEI_2
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Concluído
2011 - 2013 I want more and better cells! Stem cells: What are they? Where are they? What can they be used for?
FCOMP - 01 - 0124 - FEDER – 016898
FCOMP - 01 - 0124 - FEDER 016898
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2009/01/01 - 2012/12/31 Development of materials and coatings with antifungal properties
IAPMEI
Investigador responsável
Concluído
2008/01/01 - 2011/12/31 Design of biomimetic scaffolds from umbilical cord blood
38631
Investigador responsável
Concluído

Outro

Designação Financiadores
2009/09/01 - 2011/08/31 MATERAFUNGICIDA - Development of materials and coatings with antifungal properties
AAC 21/2008 project number 5402
Matera Lda, Portugal
 Autoridade de Gestão do Programa Operacional Competitividade e Internacionalização
Concluído
Produções

Publicações

Artigo em conferência
  1. Albino, Inês; Lino, Miguel; Ferreira, Lino. "Improved Uptake of Extracellular Vesicles in Ischemia". Trabalho apresentado em 31st Conference of the European Society for Biomaterials (ESB), Porto, 2021.
    Aceite para publicação
  2. Pitrez, Patricia R.; Vazão, Helena; Nissan, Xavier; Ferreira, Lino; Rocha, I.. "Vascular cells derived from Hutchinson-Gilford progeria syndrome (HGPS) inducible pluripotent stem cells". 2014.
Artigo em revista
  1. Magalhães, Mariana; Spigarelli, Renato; Domínguez-Martín, Eva María; Ferreira, Lino; Efferth, Thomas; Rijo, Patrícia; Spisni, Enzo; Cabral, Célia. "7a-acetoxy-6ß-hydroxyroyleanone (Roy) modulates IL-6/STAT3/JAK2 mRNA expression and suppresses tumor growth in glioblastoma cell models". Frontiers in Pharmacology 17 (2026): https://doi.org/10.3389/fphar.2026.1728792.
    10.3389/fphar.2026.1728792
  2. Salih, Abdul Rahim Chethikkattuveli; Peirsman, Arne; Khorsandi, Danial; Ferrao, Rafaela; Ferreira, Lino; Kamaraj, Meenakshi; John, Johnson V.; Baquerizo, Angeles; Jucaud, Vadim. "Liver Tissueoid on-a-Chip Modeling Liver Regeneration and Allograft Rejection". Advanced Materials (2026): https://doi.org/10.1002/adma.202521178.
    10.1002/adma.202521178
  3. Ferreira, Lino. "CASPR2 Autoimmune Antibodies Induce Neuronal Hyperactivity in Human Brain Organoids". Journal of Neurochemistry 170 2 (2026): e70.
    Publicado
  4. Elsa D Silva; Inês Tomé; Francisco Vasques-Nóvoa; Glória Conceição; Andreia Silva; António S Barros; Pedro Mendes-Ferreira; et al. "Pharmacological clearance of senescent cells reduces inflammation, endothelial damage and cardiac fibrosis in HFpEF". Cardiovascular Research (2025): http://dx.doi.org/10.1093/cvr/cvaf208.
    10.1093/cvr/cvaf208
  5. Danial Khorsandi; Jia-Wei Yang; Luis Trabucco; Rafaela Ferrao; Lino Ferreira; Mehmet Remzi Dokmeci; Ali Khademhosseini; Jing Yong Ye; Vadim Jucaud. "Real-time and label-free monitoring of monoclonal antibody secretion rates using a PC-TIR biosensor". Biosensors and Bioelectronics (2025): http://dx.doi.org/10.1016/j.bios.2025.117979.
    10.1016/j.bios.2025.117979
  6. Maria Mendes; José Sereno; Maria Luísa Ramos; Ana Fortuna; Rui Oliveira; Susana Simões; Lino Ferreira; et al. "Dual-targeted hyaluronic acid conjugates on lipid nanoparticles improve delivery and efficacy against glioblastoma: The linkage leads the fate". International Journal of Biological Macromolecules (2025): http://dx.doi.org/10.1016/j.ijbiomac.2025.148404.
    10.1016/j.ijbiomac.2025.148404
  7. Heloísa Gerardo; Tânia Lourenço; Júlio Torres; Manuela Ferreira; Célia Aveleira; Susana Simões; Lino Ferreira; et al. "Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux". European Journal of Clinical Investigation (2025): http://dx.doi.org/10.1111/eci.70051.
    10.1111/eci.70051
  8. Sandra Sofia Pinhanços; João Teixeira de Oliveira; C. Henrique Alves; Cláudia M. Deus; Twan J.J. de Winter; Sofia Viana; Flávio Reis; et al. "miRNA-642a-3p protects ß cells from glucolipotoxicity". Molecular Therapy Nucleic Acids (2025): http://dx.doi.org/10.1016/j.omtn.2025.102498.
    10.1016/j.omtn.2025.102498
  9. Luís M. Monteiro; Pedro J. Gouveia; Francisco Vasques-Nóvoa; Susana Rosa; Ifigeneia Bardi; Rita N. Gomes; Simão Correia-Santos; et al. "Nanoscale piezoelectric patches preserve electrical integrity of infarcted hearts". Materials Today Bio (2025): http://dx.doi.org/10.1016/j.mtbio.2025.101742.
    10.1016/j.mtbio.2025.101742
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  161. Ferreira, L.; Pedroso, D.C.S.; Vazão, H.; Gomes, R.S.M.. "Stem cell-based therapies for heart regeneration: What did the bench teach us?". Cardiovascular and Hematological Disorders - Drug Targets 10 3 (2010): 173-185. http://www.scopus.com/inward/record.url?eid=2-s2.0-78549255903&partnerID=MN8TOARS.
  162. Paulo, C.S.O.; Vidal, M.; Ferreira, L.S.. "Antifungal nanoparticles and surfaces". Biomacromolecules 11 10 (2010): 2810-2817. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957868674&partnerID=MN8TOARS.
    10.1021/bm100893r
  163. Ferreira, L.; Zumbuehl, A.. "Non-leaching surfaces capable of killing microorganisms on contact". Journal of Materials Chemistry 19 42 (2009): 7796-7806. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350722395&partnerID=MN8TOARS.
    10.1039/b905668h
  164. Ferreira, L.. "Nanoparticles as tools to study and control stem cells". Journal of Cellular Biochemistry 108 4 (2009): 746-752. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350435073&partnerID=MN8TOARS.
    10.1002/jcb.22303
  165. Kraehenbuehl, T.P.; Ferreira, L.S.; Zammaretti, P.; Hubbell, J.A.; Langer, R.. "Cell-responsive hydrogel for encapsulation of vascular cells". Biomaterials 30 26 (2009): 4318-4324. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650596617&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2009.04.057
  166. Fuller, J.E.; Zugates, G.T.; Ferreira, L.S.; Ow, H.S.; Nguyen, N.N.; Wiesner, U.B.; Langer, R.S.. "Intracellular delivery of core-shell fluorescent silica nanoparticles". Biomaterials 29 10 (2008): 1526-1532. http://www.scopus.com/inward/record.url?eid=2-s2.0-38549088954&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2007.11.025
  167. Mahdavi, A.; Ferreira, L.; Sundback, C.; Nichol, J.W.; Chan, E.P.; Carter, D.J.D.; Bettinger, C.J.; et al. "A biodegradable and biocompatible gecko-inspired tissue adhesive". Proceedings of the National Academy of Sciences of the United States of America 105 7 (2008): 2307-2312. http://www.scopus.com/inward/record.url?eid=2-s2.0-40649128784&partnerID=MN8TOARS.
    10.1073/pnas.0712117105
  168. Ferreira, L.; Karp, J.M.; Nobre, L.; Langer, R.. "New Opportunities: The Use of Nanotechnologies to Manipulate and Track Stem Cells". Cell Stem Cell 3 2 (2008): 136-146. http://www.scopus.com/inward/record.url?eid=2-s2.0-48349135069&partnerID=MN8TOARS.
    10.1016/j.stem.2008.07.020
  169. Ferreira, L.; Squier, T.; Park, H.; Choe, H.; Kohane, D.S.; Langer, R.. "Human embryoid bodies containing nano- And microparticulate delivery vehicles". Advanced Materials 20 12 (2008): 2285-2291. http://www.scopus.com/inward/record.url?eid=2-s2.0-48349136691&partnerID=MN8TOARS.
    10.1002/adma.200702404
  170. Ferreira, L.S.; Gerecht, S.; Fuller, J.; Shieh, H.F.; Vunjak-Novakovic, G.; Langer, R.. "Bioactive hydrogel scaffolds for controllable vascular differentiation of human embryonic stem cells". Biomaterials 28 17 (2007): 2706-2717. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947253443&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2007.01.021
  171. Ferreira, L.S.; Gerecht, S.; Shieh, H.F.; Watson, N.; Rupnick, M.A.; Dallabrida, S.M.; Vunjak-Novakovic, G.; Langer, R.. "Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle-like cells and form vascular networks in vivo". Circulation Research 101 3 (2007): 286-294. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548335261&partnerID=MN8TOARS.
    10.1161/CIRCRESAHA.107.150201
  172. Gerecht, S.; Burdick, J.A.; Ferreira, L.S.; Townsend, S.A.; Langer, R.; Vunjak-Novakovic, G.. "Hyaluronic acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells". Proceedings of the National Academy of Sciences of the United States of America 104 27 (2007): 11298-11303. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547479732&partnerID=MN8TOARS.
    10.1073/pnas.0703723104
  173. Nijst, C.L.E.; Bruggeman, J.P.; Karp, J.M.; Ferreira, L.; Zumbuehl, A.; Bettinger, C.J.; Langer, R.. "Synthesis and characterization of photocurable elastomers from poly(glycerol-co-sebacate)". Biomacromolecules 8 10 (2007): 3067-3073. http://www.scopus.com/inward/record.url?eid=2-s2.0-35548988907&partnerID=MN8TOARS.
    10.1021/bm070423u
  174. Zumbuehl, A.; Ferreira, L.; Kuhn, D.; Astashkina, A.; Long, L.; Yeo, Y.; Iaconis, T.; et al. "Antifungal hydrogels". Proceedings of the National Academy of Sciences of the United States of America 104 32 (2007): 12994-12998. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548767010&partnerID=MN8TOARS.
    10.1073/pnas.0705250104
  175. Ferreira, L.; Figueirecio, M.M.; Gil, M.H.; Ramos, M.A.. "Structural analysis of dextran-based hydrogels obtained chemoenzymatically". Journal of Biomedical Materials Research - Part B Applied Biomaterials 77 1 (2006): 55-64. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645418697&partnerID=MN8TOARS.
    10.1002/jbm.b.30394
  176. Khademhosseini, A.; Ferreira, L.; Blumling III, J.; Yeh, J.; Karp, J.M.; Fukuda, J.; Langer, R.. "Co-culture of human embryonic stem cells with murine embryonic fibroblasts on microwell-patterned substrates". Biomaterials 27 36 (2006): 5968-5977. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748769776&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2006.06.035
  177. Karp, J.M.; Ferreira, L.S.; Khademhosseini, A.; Kwon, A.H.; Yeh, J.; Langer, R.S.. "Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro". Stem Cells 24 4 (2006): 835-843. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745504422&partnerID=MN8TOARS.
    10.1634/stemcells.2005-0383
  178. Maia, J.; Ferreira, L.; Carvalho, R.; Ramos, M.A.; Gil, M.H.. "Synthesis and characterization of new injectable and degradable dextran-based hydrogels". Polymer 46 23 (2005): 9604-9614. http://www.scopus.com/inward/record.url?eid=2-s2.0-26844528911&partnerID=MN8TOARS.
    10.1016/j.polymer.2005.07.089
  179. Ferreira, L.; Evangelista, M.B.; Martins, M.C.L.; Granja, P.L.; Esteves, J.L.; Barbosa, M.A.. "Improving the adhesion of poly(ethylene terephthalate) fibers to poly(hydroxyethyl methacrylate) hydrogels by ozone treatment: Surface characterization and pull-out tests". Polymer 46 23 (2005): 9840-9850. http://www.scopus.com/inward/record.url?eid=2-s2.0-26844540116&partnerID=MN8TOARS.
    10.1016/j.polymer.2005.08.033
  180. Ferreira, L.; Gil, M.H.; Cabrita, A.M.S.; Dordick, J.S.. "Biocatalytic synthesis of highly ordered degradable dextran-based hydrogels". Biomaterials 26 23 (2005): 4707-4716. http://www.scopus.com/inward/record.url?eid=2-s2.0-14844303889&partnerID=MN8TOARS.
    10.1016/j.biomaterials.2004.11.051
  181. Ferreira, L.; Rafael, A.; Lamghari, M.; Barbosa, M.A.; Gil, M.H.; Cabrita, A.M.S.; Dordick, J.S.. "Biocompatibility of chemoenzymatically derived dextran-acrylate hydrogels". Journal of Biomedical Materials Research - Part A 68 3 (2004): 584-596. http://www.scopus.com/inward/record.url?eid=2-s2.0-1342280525&partnerID=MN8TOARS.
  182. Ferreira, L.; Ramos, M.A.; Dordick, J.S.; Gil, M.H.. "Influence of different silica derivatives in the immobilization and stabilization of a Bacillus licheniformis protease (Subtilisin Carlsberg)". Journal of Molecular Catalysis B: Enzymatic 21 4-6 (2003): 189-199. http://www.scopus.com/inward/record.url?eid=2-s2.0-0347297355&partnerID=MN8TOARS.
    10.1016/S1381-1177(02)00223-0
  183. Ferreira, L.; Gil, M.H.; Dordick, J.S.; Carvalho, R.. "Enzymatic synthesis of dextran-containing hydrogels". Biomaterials 23 19 (2002): 3957-3967. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036020043&partnerID=MN8TOARS.
    10.1016/S0142-9612(02)00132-1
  184. Ferreira, L.; Gil, M.H.; Carvalho, R.; Geraldes, C.F.G.C.; Kim, D.-Y.; Dordick, J.S.. "Biocatalytic polytransesterification of inulin with divinyladipate". Chemistry of Materials 14 10 (2002): 4009-4011. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036799646&partnerID=MN8TOARS.
    10.1021/cm020393w
  185. Ferreira, L.; Ramos, M.A.; Gil, M.H.; Dordick, J.S.. "Exquisite regioselectivity and increased transesterification activity of an immobilized Bacillus subtilis protease". Biotechnology Progress 18 5 (2002): 986-993. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036753108&partnerID=MN8TOARS.
    10.1021/bp0255457
  186. Ferreira, Lino. "Design of a drug-delivery system based on polyacrylamide hydrogels. Evaluation of structural properties". Chemical educator (2001): http://link.springer.com/article/10.1007%2Fs00897010461a.
    10.1007/s00897010461a
  187. Ferreira, L.; Vidal, M.M.; Gil, M.H.. "Evaluation of poly(2-hydroxyethyl methacrylate) gels as drug delivery systems at different pH values". International Journal of Pharmaceutics 194 2 (2000): 169-180. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033968976&partnerID=MN8TOARS.
    10.1016/S0378-5173(99)00375-0
  188. Ferreira, L.; Vidal, M.M.; Geraldes, C.F.G.C.; Gil, M.H.. "Preparation and characterization of gels based on sucrose modified with glycidyl methacrylate". Carbohydrate Polymers 41 1 (2000): 15-24. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033908440&partnerID=MN8TOARS.
    10.1016/S0144-8617(99)00064-8
Artigo em revista (magazine)
  1. Silva, Elsa D.; Nascimento, Diana S; Ferreira, Lino. "Investigadores de Coimbra e Porto rejuvenescem coração para combater insuficiência cardíaca", Diário as Beiras, 2025, https://www.asbeiras.pt/tag/esrudo/.
  2. Silva, Elsa D.; Nascimento, Diana S; Ferreira, Lino. "Investigadores do Porto e Coimbra rejuvenescem coração para combater insuficiência cardíaca", Porto Canal, 2025, https://portocanal.sapo.pt/noticia/370494.
  3. Silva, Elsa D.; Nascimento, Diana S; Ferreira, Lino. "Investigadores do Porto e Coimbra rejuvenescem coração", Jornal de Notícias, 2025
  4. Silva, Elsa D.; Nascimento, Diana S; Ferreira, Lino. "Investigadores rejuvenescem coração para combater insuficiência cardíaca", Sábado, 2025, https://www.sabado.pt/ciencia---saude/detalhe/investigadores-rejuvenescem-coracao-para-combater-insuficiencia-cardiaca.
  5. Silva, Elsa D.; Nascimento, Diana S; Ferreira, Lino. "Os investigadores usaram um modelo animal que mimetiza a HFpEF humana em contexto cardiometabólico e observaram "uma acumulação de células senescentes no sistema imunitário, nos vasos sanguíneos e no coração".", SIC Notícias, 2025, https://sicnoticias.pt/saude-e-bem-estar/2025-12-08-descoberta-forma-de-rejuvenescer-o-coracao-para-combater-insuficiencia-cardiaca-7d298398.
  6. Silva, Elsa D.; Nascimento, Diana S; Ferreira, Lino. "Investigadores do Porto e Coimbra descobrem forma de "rejuvenescer" o coração para combater insuficiência cardíaca grave", A Verdade, 2025, https://averdade.com/4008376867/investigadores-do-porto-e-coimbra-descobrem-forma-de-rejuvenescer-o-coracao-para-combater-insuficiencia-cardiaca-grave/.
  7. Silva, Elsa D.; Ferreira, Lino; Nascimento, Diana S. "Investigadores descobrem abordagem que pode “rejuvenescer o coração” e travar forma grave de insuficiência cardíaca", Mercado, 2025, https://mercado.co.ao/investigadores-descobrem-abordagem-que-pode-rejuvenescer-o-coracao-e-travar-forma-grave-de-insuficiencia-cardiaca/.
Capítulo de livro
  1. Deolinda Santinha, Andreia Vilaça, Alessandro Ori, Lino Ferreira. Autor correspondente: Deolinda Santinha, Andreia Vilaça, Alessandro Ori, Lino Ferreira. "The Extracellular Matrix in Cardiovascular Aging¿". In ¿Aging: From Fundamental Biology to Societal Impact, editado por Paulo Oliveira and João Malva. Elsevier, 2022.
    No prelo
  2. Rodrigues, Artur Filipe; Rebelo, Catarina; Reis, Tiago; Sousa, João André; Pinho, Sónia L. C.; Sargento-Freitas, João; Peça, João; Ferreira, Lino. "Therapeutic Approaches for Stroke: A Biomaterials Perspective". In Engineering Biomaterials for Neural Applications, 185-218. Springer International Publishing, 2021.
    10.1007/978-3-030-81400-7_8
  3. Rai, Akhilesh; Comune, Michela; Ferreira, Lino. "Nanoparticle-Based Drug Delivery Systems: Promising Approaches Against Bacterial Infections". In Antibacterial Drug Discovery to Combat MDR, 605-633. Springer Singapore, 2019.
    10.1007/978-981-13-9871-1_27
  4. Pitrez, Patrícia R.; Aires, Helena R.; Tomé, Inês; Ferreira, Rita Sá; Ferreira, Lino. "Physiological and Pathological Vascular Aging". In Biophysical Regulation of Vascular Differentiation and Assembly, 51-72. Springer International Publishing, 2018.
    10.1007/978-3-319-99319-5_3
  5. Estronca, L.; Ferreira, L.. "Stem Cells for the Regeneration of Chronic Wounds". In Stem Cell Manufacturing, 291-312. Elsevier, 2016.
    10.1016/b978-0-444-63265-4.00013-3
  6. Maia, João; Evangelista, Marta; Gil, M. Helena; Ferreira, Lino. "Dextran-based materials for biomedical applications". In Carbohydrates Applications in Medicine, 31-53. Kerala, Índia: Research Signpost, 2014.
    Publicado
Livro
  1. Luo, Y.; Engelmayr, G.; Auguste, D.T.; da Silva Ferreira, L.; Karp, J.M.; Saigal, R.; Langer, R.. 3D Scaffolds. 2013.
    10.1016/B978-0-12-398358-9.00024-0
  2. Spelke, D.P.; Ortmann, D.; Khademhosseini, A.; Ferreira, L.; Karp, J.M.. Methods for embryoid body formation: The microwell approach. 2011.
    10.1007/978-1-60761-962-8_10
  3. Karp, J.M.; Mahdavi, A.; Ferreira, L.S.; Khademhosseini, A.; Langer, R.. Part C: Directed Differentiation of Human Embryonic Stem Cells into Osteoblasts Cells. 2007.
    10.1002/9780470511619.ch13c
  4. Khademhosseini, A.; Karp, J.M.; Gerecht, S.; Ferreira, L.; Vunjak-Novakovic, G.; Langer, R.; Gerecht-Nir, S.; et al. Embryonic stem cells as a cell source for tissue engineering. Academic Press. 2007.
    10.1016/B978-012370615-7/50036-6
  5. Luo, Y.; Engelmayr, G.; Auguste, D.T.; Ferreira, L.D.S.; Karp, J.M.; Saigal, R.; Langer, R.. Three-dimensional scaffolds. 2007.
    10.1016/B978-012370615-7/50029-9
Poster em conferência
  1. Santos, Carolina; Campos, Elisa J.; Miguel C. Seabra; Ferreira, Lino. "A non-viral nanoformulation for mRNA delivery to the retina". Trabalho apresentado em XVI Spanish-Portuguese Conference on Controlled Drug Delivery, 2026.
  2. Rosa, Susana; Santos, Carolina; Ferreira, Lino. "Dissecting Lysosomal Dysfunction in Pompe Disease Through iPSC-Derived Muscle Models". Trabalho apresentado em Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC), 2025.
  3. Santos, Carolina; Rosa, Susana; Barreto, VM; Ferreira, Lino. "Generation of new cellular models using CRISPR-Cas9 gene editing technology for rare neuromuscular diseases". Trabalho apresentado em Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC), 2025.
  4. Helena R. Aires; Pitrez, Patricia R.; Francisco, Vitor; Ferreira, Lino; Domingues, Neuza; Raimundo, Nuno. "Nanoparticles as detonators of the senescent lysosome ticking time bomb". Trabalho apresentado em Innovative Therapies 5th CiBB Retreat, 2025.
  5. Novo, João Pedro; Thomas von Zglinicki; Rosa, Susana; Ferreira, Lino. "Unravelling and treating the ageing phenotype of the blood-brain barrier". Trabalho apresentado em BEB DAY 2025 - FROM MICRO-SCALES TO MACRO-WORLDS: TRANSCENDING THE LIMITS OF SCIENCE, 2025.
  6. A. Sofia Pinho; Renato Pereira; Pereira, Mariana; Akhilesh Rai; Ferreira, Lino; M. Cristina L. Martins; Parreira, Paula. "Breaking bad: turning the “villain” cholesterol into a hero nanotherapeutic for gastric infection management". Trabalho apresentado em 12th Galenus International Workshop, 2025.
  7. Preto, António J.; Caniceiro, Ana B.; Duarte, Francisco; Fernandes, Hugo; Ferreira, Lino; Mourão, Joana; Moreira, Irina S.. "A Data-Driven Approach to Enhancing Cell Penetrating Peptide Uptake Predictions". Trabalho apresentado em 2nd BioExcel Conference on Advances in Biomolecular Simulations, 2024.
  8. Preto, António J.; Caniceiro, Ana B.; Duarte, Francisco; Fernandes, Hugo; Ferreira, Lino; Mourão, Joana; Moreira, Irina S.. "Unveiling CPP Behavior Through Machine Learning". Trabalho apresentado em Innovative Therapies 4th CiBB Retreat, 2024.
  9. Ribeiro, Quélia; Vilaça, Andreia; Abrunhosa, Antero; Banerjee, Arnab; Ferreira, Lino. "Development of a therapeutic targeted delivery strategy to the heart". Trabalho apresentado em 2nd Portuguese Network on Extracellular Vesicles (PNEV) meeting, Lisbon, 2023.
  10. Guímaro, Carolina; Sá Ferreira, Rita; Padrão, Joana; Barão, Marta; Pitrez, Patricia R.; Ferreira, Lino. "Intracellular Delivery of Non-coding RNAs by Extracellular Vesicles". Trabalho apresentado em 3rd RESETAgeing, 2023.
  11. Lino, Miguel; Catapano, Francesco; Albino, Inês; Emanueli, Costanza; Ferreira, Lino; Ambrosetti, Elena; Teixeira, Ana. "Engineered extracellular vesicles targeting ischemic endothelial cells". Trabalho apresentado em 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC), 2022.
  12. Tenreiro, Miguel; Almeida, Henrique; Louro, Ana Filipa; Ferreira, Lino; Alves, Paula; Serra, Margarida. "Human Extracellular-Matrix Functionalization of Alginate-based Cardiac Tissues Derived from Pluripotent Stem Cells". Trabalho apresentado em Termis-EU 2020, 2020.
  13. Silva, Elsa; Silva, AM; Pereira-Sousa, Daniel; Vasques-Nóvoa, Francisco; Conceição, Gloria; Miranda-Silva, D; Pires, IF; et al. "The contribution of immune senescence to endothelial dysfunction in Heart Failure with preserved Ejection Fraction (HFpEF)". Trabalho apresentado em Winter Meeting 2020, 2020.
  14. Rodrigues, Artur Filipe; Catarina Rebelo; Pinho, Sonia L. C:; Francisco, Vitor; Ferreira, Lino. Autor correspondente: Francisco, Vitor. "High-throughput screening of combinatorial polymer library of nanoparticles for controlled delivery of mRNA". Trabalho apresentado em XIII Spanish-Portuguese Conference on Controlled Drug Delivery, 2020.
  15. Tenreiro, Miguel; Almeida, Henrique; Louro, Ana Filipa; Abecasis, Bernardo; Ferreira, Lino; Alves, Paula; Serra, Margarida. "Extracellular Matrix Functionalization of Human Cardiac Models". Trabalho apresentado em 11th International Meeting of the Portuguese Society For Stem Cells and Cell Therapies, 2019.
  16. Ana Carolina Silva Caetano; Susana Carvalho Rosa; Catarina Praça; Diana Jurk; Ferreira, Lino. "The BBB during ageing: Development of a potential in vitro BBB model.". Trabalho apresentado em iMed Conference, 2019.
Pré-impressão
  1. Lino Ferreira; Vitor Francisco; Andreia Marques; David Sanfeliu-Redondo; Ines Tome; Susana Rosa; João Pitrez; Peio Aristu-Zabalza Aristu-Zabalza; Jordi Gracia-Sancho. "Enhancing Safety and Efficacy of Senolytic Therapies with Advanced Controlled Release Strategies". 2025. https://doi.org/10.21203/rs.3.rs-5442026/v1.
    10.21203/rs.3.rs-5442026/v1
  2. Anna-Sophie Zimmermann; Sonia Sabate-Soler; Alise Zagare; Kyriaki Barmpa; Kristian Haendler; Susana Rosa; Lino Ferreira; et al. "Vascularized midbrain assembloids show neuroinflammation and dopaminergic neuron vulnerability in Parkinson’s Disease". 2025. https://doi.org/10.1101/2025.08.06.668815.
    10.1101/2025.08.06.668815
  3. Roberta Bilardo; Adele Leggieri; Francesca Tomatis; Federico Traldi; Alena Vdovchenko; Eleonora Rizzi; Miguel Lino; et al. "N-isopropylacrylamide based nanogels crossing the blood-brain barrier: evidence of high in vitro internalization in human endothelial cells and in vivo permeation in zebrafish". 2025. https://doi.org/10.26434/chemrxiv-2025-hpfg1-v2.
    10.26434/chemrxiv-2025-hpfg1-v2
  4. Sá Ferreira, Rita; Aires, Helena; Rebelo, Catarina; Passos, João F.; Ori, Alessandro; Pitrez, Patricia R.; Ferreira, Lino. "Extracellular Matrix-Associated Molecules of Senescent Cells Induce a Senescence Phenotype in Proliferative Cells Via Tgf-¿ Signaling Pathway". 2025. https://doi.org/10.2139/ssrn.5320790.
    10.2139/ssrn.5320790
  5. Magalhães, Mariana; Spigarelli, Renato; Domínguez-Martín, Eva María; Ferreira, Lino; Efferth, Thomas; Rijo, Patrícia; Spisni, Enzo; Cabral, Célia. "7a-Acetoxy-6ß-Hydroxyroyleanone (Roy) Mediates Neuroinflammatory Inhibition and Tumor Suppression in Glioblastoma". 2025. https://doi.org/10.2139/ssrn.5173448.
    10.2139/ssrn.5173448
  6. Gerardo, Heloísa; Lourenço, Tânia; Torres, Júlio; Ferreira, Manuela; Aveleira, Célia; Simões, Susana; Ferreira, Lino; et al. "Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux". 2025. https://doi.org/10.1101/2025.01.09.631485.
    10.1101/2025.01.09.631485
  7. Magalhães, Mariana; Domínguez-Martín, Eva María; Jorge, Joana; Gonçalves, Ana Cristina; Massenzio, Francesca; Spigarelli, Renato; Ribeiro-Rodrigues, Teresa; et al. "Unveiling the Antitumor Mechanism of 7a-Acetoxy-6ß-Hydroxyroyleanone from<em> Plectranthus hadiensis</em> in Glioblastoma". 2024. https://doi.org/10.20944/preprints202405.0775.v1.
    10.20944/preprints202405.0775.v1
Resumo em conferência
  1. Silva, Elsa; Tomé, Inês; Vasques-Nóvoa, Francisco; Glória Conceição; Falcão-Pires, Inês; Ferreira, Lino; Diana Nascimento. "Targeting premature aging to improve HFpEF". Trabalho apresentado em Annual Meeting of the European Tissue Repair Society (ETRS) and the Portuguese Society of Stem Cells and Cell Therapies (SPCE-TC), Coimbra, 2023.
    Publicado
  2. Silva, Elsa; Tomé, Inês; Francisco Vasques-Nóvoa; Glória Conceição; Andreia Silva; António S. Barros; Daniela Miranda-Silva; et al. "The senolyitc drug ABT-263 reverses HFpEF-associated inflammation, endothelial inflammation and fibrosis". Trabalho apresentado em Heart Failure 2021, 2022.
    Submetido

Propriedade Intelectual

Patente
  1. Rodrigues, Artur Filipe; Ferreira, Lino. 2023. "Polymeric nanoparticle formulations for targeted mRNA delivery". Portugal.
    Pendente
  2. Ferreira, Lino. 2020. "Light triggerable gene editing formulation, in vivo editing method, and used thereof".
    Pendente
  3. Ferreira, Lino. 2020. "A light-triggerable nanoparticle library of formulations for the controlled release of RNAs".
    Pendente
  4. Ferreira, Lino. 2018. "Composition and method of stem cells for preservation of cardiac tissue".
  5. Ferreira, Lino. 2017. "Use of umbilical cord blood derived exosomes for tissue repair".
    Concedida/Emitida
  6. Ferreira, Lino. 2015. "Antimicrobial complexes".
    Pendente
  7. Ferreira, Lino. 2014. "A human blood-brain barrier model derived from stem cells".
    Concedida/Emitida
  8. Ferreira, Lino. 2014. "Antimicrobial coating compositions".
    Concedida/Emitida
  9. Ferreira, Lino. 2013. "Differentiated cell population of endothelial cells derived from human pluripotent stem cells, composition, system, kit and uses thereof".
    Concedida/Emitida
  10. Ferreira, Lino. 2012. "Nanoparticles and uses thereof".
    Concedida/Emitida
  11. Ferreira, Raquel Margarida da Silva; Malva, João O.; Santos, Tiago; Bernardino, Liliana; Ferreira, Lino. 2012. "Use of histamine receptor 4 agonists and biocompatible histaminergic-loaded microparticles for the treatment of inflammatory diseases". Portugal.
  12. Ferreira, Lino. 2011. "Composition and method to improve the therapeutic effect of stem cells".
    Concedida/Emitida
  13. Ferreira, Lino. 2010. "Antimicrobial nanoparticle conjugate".
    Retirada
  14. Ferreira, Lino. 2009. "Adhesive articles".
    Concedida/Emitida
  15. Ferreira, Lino. 2009. "Particulate delivery vehicles for embryoid bodies".
    Concedida/Emitida
  16. Ferreira, Lino. 2007. "Development of Multifunctional Photocurable Degradable Elastomers".
    Concedida/Emitida
  17. Ferreira, Lino. 2007. "Amplification of cell populations from embryonic stem cells".
    Concedida/Emitida
  18. Ferreira, Lino. 2007. "Coating of devices with effector compounds".
    Concedida/Emitida
  19. Ferreira, Lino. 2007. "Formation of vascular networks using human embryonic stem cells".
    Retirada
  20. Ferreira, Lino. 2007. "Medical devices and coatings with non-leaching bioactive peptides".
    Concedida/Emitida
Pedido provisório de patente
  1. 2026. "A room-temperature 89Zr4+ radiolabelling strategy for small extracellular vesicles with enhanced plasma stability for PET Imaging".
    Divulgado
  2. 2025. "Senescence-associated nanoparticle formulations, methods and uses thereof".
    Divulgado
  3. 2024. "Polynucleotide construct for gene editing".
    Divulgado

Outros

Outra produção
  1. Differentiation of human induced-pluripotent stem cells into smooth muscle cells. 2021. Patricia R. Pitrez; Lino Ferreira. https://doi.org/10.21203/rs.3.pex-964/v1.
    10.21203/rs.3.pex-964/v1
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2025/09/07 Nanoparticles as detonators of the senescent lysosome ticking time bomb 34th Annual Conference of the European Society for Biomaterials
(Torino, Itália)
2025/09/07 The Extracellular Matrix as a Driver of Cellular Senescence 34th Annual Conference of the European Society for Biomaterials
(Torino, Itália)
2025/09/07 Overcoming biological barriers using biological and synthetic nanoparticles 34th Annual Conference of the European Society for Biomaterials
(Torino, Itália)
2025/09/07 Rejuvenating coating for bone prosthesis that improve osteogenesis 34th Annual Conference of the European Society for Biomaterials
(Torino, Itália)
2025/09/07 mRNA formulation for fibroblast targeting in the context of spinal cord injury 34th Annual Conference of the European Society for Biomaterials
(Torino, Itália)
2025/09/07 Stimuli-responsive biomaterials for tissue regeneration 34th Annual Conference of the European Society for Biomaterials
(Torino, Itália)
2025/09/07 Spatially Controlled Release of CRISPR/Cas9 formulation for Brain Gene Editing 34th Annual Conference of the European Society for Biomaterials
(Torino, Itália)
2024/06/25 Light-triggerable and other stimuli-responsive nanomaterials for targeted cardiovascular therapies 7th Termis World Congress
(Seatle, Estados Unidos)
2024/02/14 Near infrared light-activated formulation for the spatial controlled release of CRISPR-Cas9 ribonucleoprotein for brain gene editing XVI Spanish-Portuguese Conference on Controlled Drug Delivery
(Lisbon, Portugal)
2023/10/11 Efficient senotherapeutic nanoparticles targeting senescent cells European Tissue Repair Society (ETRS) & Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC)
(coimbra, Portugal)
2023/10/11 Nanoformulation with spatio-temporal control for brain gene editing European Tissue Repair Society (ETRS) & Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC)
(Coimbra, Portugal)
2023/10/11 The transition from a young to aged BBB is mediated in part by a senescence brain endothelial cell program European Tissue Repair Society (ETRS) & Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC)
(Coimbra, Portugal)
2023/10/11 Small extracellular vesicles for neuroprotection and modulation of microglia reactivity in stroke European Tissue Repair Society (ETRS) & Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC)
(Coimbra, Portugal)
2023/10/11 Disease modeling and compound screening on cardiomyocytes derived from Hutchinson-Gilford Progeria Syndrome-Induced Pluripotent Stem Cells European Tissue Repair Society (ETRS) & Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC)
(Coimbra, Portugal)
2023/10/11 Development of an in vitro human blood-brain barrier model with ageing properties European Tissue Repair Society (ETRS) & Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC)
(Coimbra, Portugal)
2023/10/11 Engineered extracellular vesicles for brain targeting European Tissue Repair Society (ETRS) & Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC)
(Coimbra, Portugal)
2023/10/11 Senotherapeutic nanoparticles to target the senescence program in the blood-brain barrier European Tissue Repair Society (ETRS) & Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC)
(Coimbra, Portugal)
2023/10/11 Engineered extracellular vesicles to modulate the blood brain barrier European Tissue Repair Society (ETRS) & Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC)
(Coimbra, Portugal)
2023/10/11 A gene editing formulation for retinal degenerative diseases European Tissue Repair Society (ETRS) & Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC)
(Coimbra, Portugal)
2023/10/11 Scalable production of Extracellular Vesicles from Mesenchymal Stem Cells using a Hollow Fiber Bioreactor European Tissue Repair Society (ETRS) & Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC)
(Coimbra, Portugal)
2023/10/11 Gene editing of aged cells with polymeric nanoparticles European Tissue Repair Society (ETRS) & Portuguese Society for Stem Cells and Cell Therapy (SPCE-TC)
(Coimbra, Portugal)
2023/09/04 Near infrared light-activated formulation for the spatial controlled release of CRISPR-Cas9 ribonucleoprotein for brain gene editing 33rd Annual Conference of the European Society for Biomaterials
(Davos, Suiça)
2023/09/04 Piezoelectric patches preserve electrical integrity of cardiac tissue 33rd Annual Conference of the European Society for Biomaterials
(Davos, Suiça)
2023/09/04 Targeting the senescence program in the blood brain barrier with senotherapeutic nanoparticles 33rd Annual Conference of the European Society for Biomaterials
(Davos, Suiça)
2023/06/29 Extracellular matrix during chronological and pathological cardiac ageing: a proteomic study DGfA - German Society for Aging Research
(Jena, Alemanha)
2023/06/29 Senotherapeutic nanoparticles to target senescent cells in the liver DGfA - German Society for Aging Research
(Jena, Alemanha)
2023/06/29 The transition from a young to aged BBB is mediated in part by a senescence brain endothelial cell program DGfA - German Society for Aging Research
(Jena, Portugal)
2023/06/22 Development of a therapeutic targeted delivery strategy to the heart 2nd Portuguese Network on Extracellular Vesicles (PNEV) meeting, Lisbon
(Lisbon, Portugal)
2023/06/22 A new radiolabeling strategy for extracellular vesicles (EVs) using 89Zr4+ for in vivo monitoring via PET Imaging 2nd Portuguese Network on Extracellular Vesicles (PNEV) meeting, Lisbon
(Lisbon, Portugal)
2023/06/07 Nanoformulation with spatio-temporal control for brain gene editing 57th Annual Scientific Meeting of the European Society for Clinical Investigation
(Prague, República Checa)
2023/06/07 Targeted delivery of therapeutic agents to the heart 57th Annual Scientific Meeting of the European Society for Clinical Investigation
(Prague, República Checa)
2023/06/07 Engineered extracellular vesicles for the treatment of ischemic diseases 57th Annual Scientific Meeting of the European Society for Clinical Investigation
(Prague, República Checa)
2023/06/07 An improved radiolabeling strategy of small extracellular vesicles (sEVs) employing 89Zr4+ for prolonged in vivo monitoring using PET imaging 57th Annual Scientific Meeting of the European Society for Clinical Investigation
(Prague, Portugal)
2023/06/07 Synergistic antimicrobial effect between antimicrobial peptides conjugated nanoparticles 57th Annual Scientific Meeting of the European Society for Clinical Investigation
(Prague, República Checa)
2023/05/03 Engineering extracellular vesicles to cross the blood-brain barrier FENS Regional Meeting
(Algarve, Portugal)
2021/09/05 Modulation of stem cells using nanotechnologies
31st Conference of the European Society for Biomaterials (ESB) together with the 43rd Annual Congress of the Iberian Society of Biomechanics and Biomaterials (SIBB) (Virtually)
2020/12/18 Non-coding RNA-engineered extracellular vesicles for cardiac regeneration
Portuguese Network of Extracellular Vesicles (Porto)
2020/12/04 O envelhecimento visto sobre o olhar da medicina regenerativa EMBS
(Coimbra, Portugal)
2020/06/23 O envelhecimento visto sobre o olhar da medicina regenerativa Ciclo de conferencias CULTURGEST sobre a temática “LIFE>TIME: a vida maior que o tempo”
Culturgest (Lisboa, Portugal)
2019/11/22 Physiological and pathological cardiovascular ageing: models and therapies
Sociedade Portuguesa de Cirurgia Cardiotorácica e Vascular (Albufeira, Portugal)
2019/11/06 The kinetics of small extracellular vesicle delivery impacts skin tissue regeneration
5th GEIVEX Symposium (Granada, Espanha)
2019/10/10 Prolonged intracellular accumulation of light inducible nanoparticles in leukemia cells allows their remote activation
SPCE-TC (Lisboa, Portugal)
2019/07/23 Light-activatable (nano)materials for cell regulation
41st Annual International conference of the IEEE Engineering in Medicine and Biology Society (Berlin, Alemanha)
2019/06/28 Physiological and pathological cardiovascular ageing: models and therapies Ageing conference
(Coimbra, Portugal)
2019/06/28 Physiological and pathological cardiovascular ageing: models and therapies Ageing: models, mechanisms and therapies
(Coimbra, Portugal)
2019/06/23 Light-activatable (nano)materials for cell regulation Nanofar: European doctorate in nanomedicine
(Angers, França)
2019/05/22 Therapies and stem cell-based models for cardiovascular applications 53rd ESCI2019
Annual scientific meeting of the European Society for Clinical Investigation (Coimbra, Portugal)
2019/04/01 Mechanical forces in vascular cell maturation and disease Mechanobiology of migrating cells: from basic science to the clinic
Cost Action CA15214 (EuroCellNet) working group meeting (Coimbra, Portugal)
2019/01/31 Light-activatable (nano)materials for cell regulation Advanced theranostic nanomedicine in oncology
ERC Starting Grant SLaMM Workshop (Pisa, Itália)
2019/01/16 Light-activatable (nano)materials for cell regulation Nanotechnology for therapy and diagnostics
International Iberian nanotechnology Laboratory (Braga, Portugal)
2018/11/07 Induced pluripotent stem cell-derived tissues for drug screening and disease modeling
Sociedade Portuguesa de Biologia de Desenvolvimento (Porto, Portugal)
2018/10/11 Engineered cardiac tissues and stem cell-based therapies for cardiovascular applications Reunião Anual da APIC'18
(Troia, Portugal)
2018/09/09 Light-activatable (nano)materials for cell regulation
European Society of Biomaterials (Maastricht, Países Baixos)
2018/07/04 Innovative therapies for age-associated diseases Programa Ciencia
(Lisboa, Portugal)
2018/06/27 Ageing vascular model from iPSCs for the identification of new therapies Workshop ERA Chair
(Coimbra, Portugal)
2018/02/05 Peptide-conjugated nanomaterials for biomedical applications
16th Iberian Peptide Meeting/ 4th ChemBio Group meeting (Barcelona, Espanha)
2018/01/14 Drug delivery in regenerative medicine Tailoring drug delivery systems to the patients needs
XII Spanish-Portuguese conference on controlled drug delivery (Coimbra, Portugal)
2017/09/30 ERA@UC: Enhancing research in aging at the University of Coimbra Congresso Nacional de Medicina Geral e Familiar
(Vila Real, Portugal)
2017/04/08 Stem cell-based models for cardiovascular diseases Symposium on bioengineering
Universidade do Porto (Porto, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2025/09/01 - 2029 Development of non-viral delivery formulations to reprogram glial cells into neurons
Orientador
2025/09/01 - 2029 A non-viral system to rejuvenate and reprogram aged glial cells
Orientador
2025/09/01 - 2029 miRNAs-EVs as a Targeted Anti-Senescence Therapy
Orientador
2024/09/01 - 2028 Cellular reprogramming of brain tissue monitored by spatial transcriptomics
Orientador
2019/09/01 - 2026/02/13 Engineering strategies for the delivery of extracellular vesicles into the heart
Orientador
2022/01/01 - 2026 Targeted Formulations for Cell Senescence
Orientador de Andreia Marques
Universidade de Coimbra, Portugal
2021/11/01 - 2026 Unravelling and treating blood-brain barrier dysfunction upon ageing
Orientador de João Pedro Ferreira da Costa Novo
Universidade de Coimbra, Portugal
2020/09/01 - 2026 Engineering extracellular vesicles to enhance wound healing
Orientador
2019/04/01 - 2026 Engineered formulations for gene editing
Orientador de Angela Barrera
Universidade de Coimbra Faculdade de Medicina, Portugal
2019/09/01 - 2025/12/31 New pharmacological interventions to eliminate senescent cells
Orientador
2018/09/01 - 2025/07/02 New platforms for brain targeting and modulation
Orientador de Ines Maria Cunha Albino
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/10 - 2025/05/30 Remodeling of the cardiac extracelular matrix during aging
Orientador de Deolinda da Conceição Ribafeita Santinha
 Envelhecimento e Doenças Crónicas (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2021/01/01 - 2025/03/18 Scarless healing: harnessing the wound healing potential of the oral mucosa
Coorientador
2020/09/01 - 2025/01/17 Enzymatic synthesis of RNA-peptide conjugates as potential therapeutics for Covid-19
Coorientador
2019/09/01 - 2024/12/18 The missing link between the immune system and endothelial/myocardial dysfunction in HFpEF, from patients to models and back
Coorientador
2019/09/01 - 2024/12/09 Pharmacological strategies to target cellular senescence
Orientador
2018/09/01 - 2024/07/22 Gene editing nanoformulations for brain applications
Orientador de Francesca Tomatis
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/12/01 - 2023/12/11 Engineering an aged cardiac tissue from human pluripotent stem cells
Orientador de Luís Miguel de Almeida Monteiro
 Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2016/08 - 2022/10/18 A multi-approach platform to identify biomolecules for cardiac regeneration
Orientador de Andreia Pinheiro Vilaça
 Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2015/02/10 - 2022/07/13 Bioactive nanovesicles from umbilical cord blood to treat diabetic chronic wounds
Orientador
2016/08/01 - 2022/03/29 Vascular cell senescence: triggers and therapeutic strategies
Orientador de Rita Rodrigues Sá Ferreira
 Biotecnologia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2016/08/01 - 2022/02/21 Extracellular vesicles as platforms for therapeutic microRNA delivery
Orientador de Ricardo Cerqueira de Abreu
 Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2012/03 - 2021/01/11 Biocompatible nanoparticles to modulate cell activity
Orientador de Josephine Blersch
 Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2015/01 - 2019/12 Light-triggerable delivery of a gene edition system
Orientador de Catarina Araujo Gomes Rebelo
Bioengenharia (Doutoramento)
Universidade Nova de Lisboa, Portugal
2018/06 - 2019/09 Investigation of the Blood-Brain Barrier ageing for the development of an in vitro model
Orientador de Ana Carolina Silva Caetano
 Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/03 - 2018/12 Modulation of the hematopoietic stem cell niche by photo-triggerable nanoparticles
Coorientador de Emanuel Nery de Oliveira Quartin Costa
 Bioengenharia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011/08 - 2018/11 Endothelial precursor cells in neoangiogenesis of acute ischemiq stroke
Orientador de João André Sargento Araujo de Freitas
 Ciências da Saúde
Universidade de Coimbra Faculdade de Medicina, Portugal
2013/09 - 2018/10 Engineering human in vitro cardiac tissue models for preclinical research
Coorientador de Bernardo Martins da Cunha Abecasis
 Engenharia Biológica (Doutoramento)
Universidade Nova de Lisboa, Portugal
2017/07 - 2018/09 Urine extracellular vesicles: waste or a powerful tool?
Coorientador de Carlos Alberto Gaspar de Jesus
 Investigação Biomédica (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2017/05 - 2018/09 Breaking the barriers of HFpEF: a New "Blood Vessel on a Chip" Model
Coorientador de Ines Tomé Ribeiro
 Investigação Biomédica (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2017/05 - 2018/09 High-throughput identification of polymeric compounds that affect human vascular cell senescence
Coorientador de Helena Isabel Reis Aires
 Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/09 - 2018/07 Encapsulation of vascular cells in fibrin gels: assessment of cell viability, proliferation, migration and organization
Orientador de Rita Alexandra Lopes dos Santos
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/01/01 - 2017/12/01 MicroRNA-124-loaded nanoparticles as a new promising therapeutic tool for neural stem cell-based brain repair strategies
Coorientador
2012/07 - 2017/12 Vascular organ-on-a-chip platforms for disease modeling
Orientador de João Carlos Ribas de Almeida
 Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2012/09 - 2017/10 Stem cell and stem cell-free based therapeutics against myocardial infarction
Orientador de Ivana Kostic
 Bioengenharia (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016/05 - 2017/06 Exosomes-based therapy for stroke
Coorientador de Antonio José da Silva Santinha
 Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012/02 - 2017/06 Light-triggerable nanomaterials for the delivery of biomolecules
Orientador de Miguel Maria da Fonseca Miranda Ferreira Lino
 Biociências (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011/09 - 2017/02 Brain-like endothelial cells derived from stem cells to study BBB development and targeting
Orientador
 Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2015/05 - 2016/10 Development of a photo-triggerable nanoparticle for efficient intracellular delivery of siRNA
Orientador
 Bioengenharia (Mestrado)
Universidade do Porto, Portugal
2015/05 - 2016/10 Evaluation of the therapeutic potential of piezoelectric fibers-coated thin films for the treatment of myocardial infarction
Coorientador de Luis Miguel de Almeida Monteiro
 Bioengenharia (Mestrado)
Universidade do Porto, Portugal
2015/05 - 2016/07 Prevention of Intravascular Catheter-Related Infections
Coorientador de Micaela Alexandra Machado Querido
 Engenharia Biomédica (Mestrado)
Universidade do Porto, Portugal
2011/12 - 2016/06 Wound healing and pro-angiogenic properties of LL37-conjugated nanoparticles
Orientador de Michela Comune
 Biociências (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010/09 - 2016/06 Cardiac tissue constructs for drug screening
Orientador de Pedro José Azeredo de São Bento Gouveia
 Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2010/09 - 2016/06 Bioengineering platform to modulate the activity of smooth muscle cells derived from Progeria induced pluripotent stem cells
Orientador de Patrícia Raquel Pinheiro Pitrez Pereira
Bioengenharia (Doutoramento)
Universidade do Minho, Portugal
2009/09 - 2015/01 Leukemia cells modulation by light-activatable nanoparticles
Coorientador de Carlos Samuel Marques Boto
Engenharia Química (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008/09 - 2013/12 Nanomaterials for Mirna Delivery and Non-Invasive Imaging in Cardiovascular Regeneration
Orientador de Renata Sofia Mota Gomes
 Bioquímica (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008/09 - 2013/12 Platforms to modulate the activity of hematopoietic stem cells and their progenies
Orientador de Sezin Aday
 Bioengenharia (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2008/09 - 2013/07 Platforms for tissue reconstruction: compliant biomaterials for local drug delivery and tissue adhesion
Orientador de Maria José Maio Nunes Pereira
 Bioengenharia (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2011/11 - 2013/04 High-throughput screening to discover compounds that enhance the proliferative and metabolic activity of tendon or ligament cells and improve the proliferation of endothelial cells
Coorientador de Tânia Luisa Barbosa Barata
 Biotecnologia para as Ciências da Saúde (Mestrado)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2008/03 - 2012/12 Approaches to improve the differentiation, maturation and biological activity of vascular cells derived from stem cells
Orientador de Helena Sofia Esmeraldo de Campos Vazão
 Biologia (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007/09 - 2012/11 Permanent antifungal materials and coatings: bioactivity and cytotoxicity characterization
Orientador
 Biotecnologia (Doutoramento)
Universidade de Lisboa, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2025/09/07 - 2025/09/11 Symposium "Drug delivery systems: overcoming biological barriers", 34th Annual Conference of ESB, 7-11th September 2025, Torino, Italy (2025/09/07 - 2025/09/11)
Congresso (Coorganizador)
2025/04/23 - 2025/04/27 Symposium “EVs for drug delivery in the context of regeneration and organ rejuvenation”, ISEV2025 Annual Meeting, 23 – 27 April 2025, Vienna, Austria (2025/04/23)
Congresso (Coorganizador)
2024/06/25 - 2024/06/28 Symposium “Biophysical Stimuli and Stimuli-Responsive Materials for Drug Delivery and Tissue Regeneration”, 7th TERMIS World Congress, June 25-28, Seattle, WA, USA (2024/06/25)
Congresso (Coorganizador)
2023/09/04 - 2023/09/08 Chair of the symposium “Drug delivery for tissue regeneration and reset aging”, 33rd Annual Conference of ESB, 4-8th September 2023, Davos, Switzerland (2023/09/04 - 2023/09/08)
Congresso (Coorganizador)
2023/06/07 - 2023/06/08 Symposium “Regenerative Medicine and Gene/Cell therapy”, 57th Annual Meeting of ESCI, June 7-8th, Prague, Czech Republique (2023/06/07)
Congresso
2022/06/08 - 2022/06/10 Symposium “Gene and Cell therapy: from fundamental science to the clinic”, 56th Annual Meeting of ESCI, June 8-10th, Bari, Italy (2022/06/08)
Congresso (Coorganizador)
2021/09/05 - 2021/09/09 Symposium “Nanostructure-based biomaterials: design and biological interactions”, 31st conference of the European Society of Biomaterials (ESB), September 5-9th, online (2021/09/05 - 2021/09/09)
Conferência (Outra)
 European Society of Biomaterials, França
2021/06/09 - 2021/06/11 Symposium “Regenerative and genomic medicine”, 55th annual ESCI scientific meeting, 9-11 June, online (2021/06/09 - 2021/06/11)
Conferência (Outra)
 European Society for Clinical Investigation, Países Baixos
2021/06/01 - 2021/06/04 Symposium “Cardiovascular ageing and regenerative medicine”, 6th World congress of TERMIS, June 1-4th, online (2021/06/01 - 2021/06/04)
Conferência (Outra)
 Tissue Engineering and Regenerative Medicine International Society, Estados Unidos
2020/05/27 - 2020/05/29 Symposium entitled "Stem cells & cell therapies" (2020/05/27 - 2020/05/29)
Conferência (Outra)
 European Society for Clinical Investigation, Países Baixos
2019/06/28 - 2019/06/29 International conference on “Ageing: models, mechanisms and therapies” (2019/06/28 - 2019/06/29)
Conferência (Presidente da Comissão Organizadora)
 Universidade de Coimbra Faculdade de Medicina, Portugal
2019/05/22 - 2019/05/24 Symposium “Gene and Cell therapy: from fundamental science to the clinic”, European Society for Clinical Investigation, May 22-24th, Coimbra (2019/05/22 - 2019/05/24)
Conferência (Outra)
 European Society for Clinical Investigation, Países Baixos
2018/09/10 - 2018/09/13 Symposium “Nanostructured biomaterials for cell regulation”, European Society of Biomaterials, September 10-13th, Maastricht, Netherlands (2018/09/10 - 2018/09/13)
Conferência (Outra)
 European Society of Biomaterials, França
2018/06/27 - 2018/06/27 Workshop on “Ageing: models and therapies” (2018/06/27 - 2018/06/27)
Oficina (workshop) (Presidente da Comissão Organizadora)
 Universidade de Coimbra Faculdade de Medicina, Portugal
2016/07/07 - 2016/07/08 German-Portuguese student Workshop on “Translation in Biomaterials and Stem Cell Research” (2016/07/07 - 2016/07/08)
Oficina (workshop) (Presidente da Comissão Organizadora)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/06/27 - 2016/06/27 Stem cell workshop: from basic research to clinical applications (2016/06/27 - 2016/06/27)
Oficina (workshop) (Membro da Comissão Organizadora)
 Centro Hospitalar e Universitario de Coimbra EPE Campus dos Hospitais da Universidade de Coimbra, Portugal
2014/12/17 - 2014/12/20 Symposium entitled "Tissue engineering and regenerative medicine"- XVIII Congress of the Portuguese Biochemical Society, 17-20 December, Coimbra, Portugal (2014/12/17 - 2014/12/20)
Congresso (Outra)
 Sociedade Portuguesa de Bioquímica, Portugal
2014/11/28 - 2014/11/29 “Heart without Borders”- International conference in cardiovascular development, disease and repair (2014/11/28 - 2014/11/29)
Conferência (Membro da Comissão Organizadora)
2014/03/24 - 2014/03/24 Workshop on Stem cells: from basic research to therapeutic applications, Centro do Sangue e Transplantação de Coimbra (2014/03/24 - 2014/03/24)
Oficina (workshop) (Presidente da Comissão Organizadora)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/09/09 - 2013/09/10 German-Portuguese student Workshop on “Matrix Engineering meets Stem Cell Therapy” (2013/09/09 - 2013/09/10)
Oficina (workshop) (Presidente da Comissão Organizadora)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/07/19 - 2013/07/20 First International Conference on Stem Cells for Drug Screening and Regenerative Medicine (2013/07/19 - 2013/07/20)
Conferência (Presidente da Comissão Organizadora)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2011/04/28 - 2011/04/29 6th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies (2011/04/28 - 2011/04/29)
Congresso (Presidente da Comissão Organizadora)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2010/06/18 - 2010/06/18 Fourth Annual Workshop on the Business-Government Interface: Personalized Medicine (2010/06/18 - 2010/06/18)
Oficina (workshop) (Presidente da Comissão Organizadora)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009/06/02 - 2009/06/02 Third Annual Workshop on the Business-Government Interface: Challenges in Cell and Gene Therapies (2009/06/02 - 2009/06/02)
Oficina (workshop) (Presidente da Comissão Organizadora)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2003/06/28 - 2003/07/04 4th Advanced Course in Cell-Material Interactions
Outro
 4th Advanced Course in Cell-Material Interactions

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2025/12/10 Understanding the aging process: from DNA damage to stem cells
Arguente
 Bruno Bernardes de Jesus (Agregação)
Universidade de Aveiro, Portugal
2024/11/08 A Bridge Between Development and Engineering: Creating Liver Organoids from Human Induced Pluripotent Stem Cells
Arguente principal
 João Pedro Brinquete Cotovio (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2024/07/08 Bioengineering Approaches for Cell Based Products
Arguente
 Paula Maria Marques Leal Sanches Alves (Agregação)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal
2024/04/29 The role of protein quality control and intercellular communication in cardiovascular diseases
Arguente
 Teresa Margarida Ribeiro Rodrigues (Doutoramento)
Universidade de Coimbra, Portugal
2023/07/24 Metabolic Regulation of Neural Stem Cells for Brain Regeneration
Arguente
 Susana Zeferino Solá da Cruz (Agregação)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/04/25 Nose-to-brain delivery of nanomedicine to stimulate remyelination in the scope of multiple sclerosis
Arguente principal
 Ariane Mwema (Doutoramento)
Université catholique de Louvain, Bélgica
2023/02/01 Design, preparation and characterization of synthetic and physiological nanovectors for the diagnosis and therapy of cancer and neurological diseases
Arguente
 Federica Rizzi (Doutoramento)
Università degli Studi di Bari Aldo Moro, Itália
2023/01/30 A 3D graphene composite scaffold with a combinatorial fibrous-porous architecture for neural repair in the injured spinal cord
Arguente principal
 André Francisco Oliveira Girão (Doutoramento)
Universidade de Aveiro, Portugal
2022/11/25 An Innovative Therapeutic Approach For Infected Chronic Wounds
Arguente principal
 Ana Isabel da Silva Mendes (Doutoramento)
Universidade do Minho Escola de Medicina, Portugal
2022/10/24 Cancer epigenetics: from the laboratory bench to the clinic
Arguente
 Pedro Jorge Gomes Teodósio Castelo Branco (Agregação)
Universidade do Algarve, Portugal
2022/09/01 Diverse applications of cell-based assays for drug discovery
Arguente principal
 André Lopes Rodrigues (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/07/11 Transcription Factors, microRNAs and Extracellular Vesicles at the crossroad of right and left heart failure
Arguente
 Raquel Figuinha Videira (Doutoramento)
Universiteit Maastricht Department of International Health, Países Baixos
2022/03/21 “Forever young”: Targeting cellular senescence for healthspan and lifespan extension
Arguente
 Rui Sérgio Ribeiro (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/01/07 Bioengineering an Immunomodulatory Microenvironment for Bone Healing
Arguente principal
 Mafalda Bessa Martins Gonc¸alves (Doutoramento)
Universidade do Porto, Portugal
2021/05/28 Extracellular vesicles at the heart of cell-cell communication
Arguente principal
 Lara Ottaviani (Doutoramento)
Universiteit Maastricht Department of Pharmacology and Toxicology, Países Baixos
2021/05/25 Role of cholesteryl-hemiesters in the etiology of atherogenesis
Arguente principal
 Liliana Teresa da Silva Alves (Doutoramento)
Universidade Nova de Lisboa, Portugal
2021/04/27 Development of theranostic nanostructures for early stages of Alzheimer ´s Disease
Arguente principal
 Manuel Rodríguez Pérez (Doutoramento)
Universidade de Santiago de Compostela, Espanha
2021/03/19 Development of Human Pluripotent Stem Cell-derived Cardiovascular Microtissues for Cardiotoxicity Screening
Arguente principal
 Mariana da Mota Veiga de Araujo Branco (Doutoramento)
Universidade de Lisboa, Portugal
2021/01/19 Bioprocess development for scalable generation of functional liver micro- tissues/organoids from human pluripotent stem cells
Arguente principal
 Saeed Abbasalizadeh (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/01/13 New cells to mend an old heart
Arguente
 José Eduardo Marques Bragança (Agregação)
Universidade do Algarve, Portugal
2020/06/26 New Active Nanomaterials for Stem Cell Differentiation in Bone Regeneration
Arguente principal
 Márcia Tojeira Tavares (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/05/22 Developing cellular models for hypertrophic cardiomyopathy
Arguente principal
 Marta de Jesus Ribeiro (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/04/28 Tuning extracellular cues to regulate epithelial cell phenotype
Arguente principal
 Maria João Pardelha da Cruz (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/03/23 Molecular mechanism of horizontal mitochondrial transfer from stroll cells to cancer cells with damaged mitochondrial DNA
Arguente
 Ana Raquel Ligeiro Coelho (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/02/14 Induced pluripotent stem cells as a new approach in therapy for stroke
Arguente principal
 Esteban López Arias (Doutoramento)
Universidade de Santiago de Compostela, Espanha
2020/01/07 Three-dimensional culture systems for the study of human pluripotent stem cells: microarrays and spheroids
Arguente
 Jorge Filipe da Conceição Pascoal (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/12/12 Gold Nanoparticles to Tackle Drug Resistance in Cancer
Arguente principal
 Pedro Miguel Pinto Gonçalves Gouveia Pedrosa (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/05/28 Novel therapeutic approach to amyotrophic lateral sclerosis: targeting neurotoxic astrocytes before transplantation
Arguente
 Cátia Sofia Vicente Gomes (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/05/15 Modeling Radiation Injury and Countermeasure Drug Responses in a Human Intestine Chip
Arguente principal
 Sasan Jalili Firoozinezhad (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/04/05 Study of Biophysical Interactions and Antibody Bioactivity of Bevacizumab Encapsulated into Nanoparticles Towards its Controlled Release
Arguente principal
 Flavia Sousa (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/12/21 Insights into gold nanoparticles functionalized with cysteine-terminated cecropia mellitus and cathelicidin-derived antimicrobial peptides- a computational approach
Vogal
 André Filipe Simões Ferreira (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/09/18 A therapeutic epicardial reservoir for the treatment of cardiac disease
Arguente principal
 William White (Doutoramento)
Trinity College Dublin School of Medicine, Irlanda
2018/07 Identification of native cardiogenic niche-feature(s) for improved cardiac cell response: the role of the extracellular matrix
Arguente principal
 Ana Catarina de Andrade e Silva (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/05 CLAMP - CLick chemistry as a tool to create AntiMicrobial Peptide-based materials
Arguente principal
 Mariana Moreira da Silva Alves Barbosa (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2017/12 VASCULAR ORGAN-ON-A-CHIP PLATFORMS FOR DISEASE MODELING
Orientador
 João Carlos Ribas de Almeida (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2017/12 Effect of industrial GMP human plasma derived supplement on hMSC behaviour
Vogal
 Maura Cimino (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2017/10 Stem cell and stem cell-free based therapeutics against myocardial infarction
Orientador
 Ivana Kostic (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/07 Novel nanoparticle-based drug delivery system for neural stem cell targeting and differentiation
Arguente principal
 Dario Carradori (Doutoramento)
Université catholique de Louvain - Mons, Bélgica

Université d'Angers, França
2017/06 Light-triggerable nanomaterials for the delivery of biomolecules
Orientador
 Miguel Maria da Fonseca Miranda Ferreira Lino (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/03 Tribos transformation of Escherichia coli JM109
Arguente principal
 Gabriel Pinto Mendes (Doutoramento)
Universidade do Minho, Portugal
2017/02 Bioprocessing of human pluripotent stem cells for cardiac cell therapy and pre-clinical research
Arguente principal
 Claudia Susana Pedreira Correia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/02 Brain-like endothelial cells derived from stem cells to study BBB development and targeting
Orientador
 Catarina Oliveira Praça de Almeida (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2017/01 Scalable manufacturing of mesenchymal stem/stromal cells for cell therapies and the role of the Notch signaling pathway in the human hematopoietic system
Arguente principal
 Antonio Maria Santa Marta de Soure (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016/09 Cicatrização de feridas de pele e actividade pro-angiogénica das nanopartículas conjugadas com LL37
Orientador
 Michela Comune (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016/07 Development of an injectable dextrin hydrogel for bone regeneration
Arguente principal
 Dina Maria Morais da Silva (Doutoramento)
Universidade do Minho, Portugal
2016/07 Role of Ccbe1 during cardiac differentiation of mouse ESCs
Arguente principal
 Tiago Manuel Santos Justo (Doutoramento)
Universidade do Algarve, Portugal
2016/06 Cardiac tissue constructs for drug screening
Orientador
 Pedro José Azeredo de São Bento Gouveia (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2016/06 Bioengineering platforms to modulate the activity of smooth muscle cells derived from progeria-induced pluripotent stem cells
Orientador
 Patricia Raquel Pinheiro Pitrez Pereira (Doutoramento)
Universidade do Minho, Portugal
2016/05 Human Pluripotent Stem Cell Signaling and Cardiac Lineage Commitment
Arguente principal
 Tiago Miguel Peixoto Dias (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2015/12 Fine-tuning neurogenesis: microRNA regulatory networks
Arguente principal
 Ana Luisa Silva Neves Morgado (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015/12 Oxazoline-based Antimicrobial Platforms for Water Treatment
Arguente principal
 Vanessa Fernandes Gomes Correia (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/11 Surface-immobilized Antimicrobial Peptides (AMPs) for prevention of implant-related osteomyelitis
Arguente principal
 Fabíola Maria Tavares Alves da Costa Moutinho (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2015/11 Engineered MRI nanoprobes based on superparamagnetic iron oxide nanoparticles
Arguente principal
 Susana Isabel Conde Jesus Palma (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015/01 Endothelial Progenitor Cells of Diabetic Patients with Acute Coronary Syndromes: Effects of Antidiabetic and Lipid Lowering Drugs
Vogal
 Natália Sofia Claudio António (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015/01 Leukemia Cells Modulation By Light-Activatable Nanoparticles
Orientador
 Carlos Samuel Marques Boto (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014/12 Polyurea-based Dendrimers Therapeutics
Vogal
 Ana Rita Bernardo Restani Silva (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2014/12 Mecanismos moleculares subjacentes à biologia da pluripotência induzida
Vogal
 Rodrigo Luiz dos Santos (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2014/11 Deconstruction CD44 - Engineering 3 D matrices to elucidate CD44 modulation in gastric malignancy
Arguente principal
 Cristiana Tavares Branco da Cunha (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
2014/10 Desenvolvimento de Materiais Poliméricos para Inibição de Quorum Sensing
Arguente principal
 Eliana Marisa dos Santos (Doutoramento)
Universidade de Aveiro, Portugal
2014/05 STUDY OF THE APPLICATION POTENTIAL OF SYNTHETIC AND NATURAL POLYMERIC COATINGS IN STEM CELL RESEARCH
Arguente principal
 Ana Rubina Nóbrega Perestrelo (Doutoramento)
Universidade do Algarve, Portugal
2013/12 Desenvolvimento de Matrizes Biomiméticas como Substitutos de Pele Destinados ao Tratamento de Queimaduras
Arguente principal
 Susana Raquel Rodrigues Gomes (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013/12 Migration and differentiation of neuronal precursors in the postnatal brain: insights from the subventricular zone and cerebellum
Vogal
 Maria Francisca Eiriz (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2013/12 PLATFORMS TO MODULATE THE ACTIVITY OF HEMATOPOIETIC STEM CELLS AND THEIR PROGENIES
Orientador
 Sezin Aday (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013/12 Nanomateriais, miRNA, imagem não-invasiva na regeneração cardiovascular
Orientador
 Renata Sofia Mota Gomes (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/09 Studies on high molecular weight poly(lactic acid) synthesis
Vogal
 Dina Augusta Simões Marques (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/07 Platforms for tissue reconstruction: compliant biomaterials for local drug delivery and tissue adhesion
Orientador
 Maria José Maio Nunes Pereira (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2013/01 Protease-sensitive hydrogels as 3D cellular microenvironments
Arguente principal
 Keila Beltrame Fonseca (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2012/12 Approaches to Improve the Differentiation, Maturation and Biological Activity of Vascular Cells Derived from Stem Cells.
Orientador
 Helena Sofia Esmeraldo de Campos Vazão (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012/11 PERMANENT ANTIFUNGAL MATERIALS AND COATINGS: BIOACTIVITY AND CYTOTOXICITY CHARACTERIZATION
Orientador
 Cristiana da Silva Oliveira Paulo (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012/07 Molecular design of surfaces towards more effective anticoagulation strategies for blood-contacting medical devices
Arguente principal
 Sidónio Ricardo da Cunha Freitas (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2012/07 Electrospun fibrous mats for skin and abdominal wall repair
Arguente principal
 Maria Beatriz da Rocha Veleirinho (Doutoramento)
Universidade de Aveiro, Portugal
2012/04 Development of Bio-Hybrid Actuators
Arguente principal
 Leonardo Ricotti (Doutoramento)
Scuola Superiore Sant'Anna, Itália
2012/04 EX VIVO ENGINEERED COMBINATORIAL u-ENVIRONMENTS FOR STEM CELL FATE STUDIES: THE BALANCE BETWEEN STEM CELL SELF-RENEWAL AND DIFFERENTIATION
Arguente principal
 David Fernandes Braga Malta (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2012/02 Process Engineering of Liver Cells for Drug Testing Applications
Arguente principal
 Rui Manuel Lucas Gameiro Domingues Tostões (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011/12 Bioactive Beads for Local Modulation and Sensing of Cell Mechanical Environment in 3d Engineered Tissues
Arguente principal
 Eunice Margarida Santos Costa (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2011/11 Exploring the crosstalk between mesenchymal stem cells and endothelial cells in bone tissue engineering
Arguente principal
 Silvia Joana Bidarra dos Santos Lourenço (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
2011/10 Recombinant expression and Activity of cationic antimicrobial peptides
Arguente principal
 Reinaldo Rodrigues Ramos (Doutoramento)
Universidade do Minho, Portugal
2011/07/01 Role of the notch-delta signalling pathway on bone marrow-derived cells function during wound healing and tumor progression
Arguente
 Francisco Landeck Moreira Manso Caiado (Doutoramento)
Universidade de Lisboa, Portugal
2011/07/01 Novel Approaches for the Isolation and Ex-vivo Expansion of Hematopoietic stem cells from human umbilical cord blood for Cell Therapy
Arguente
 Pedro Miguel Zacarias Andrade (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2011/04/01 Drug Delivery Systems for Tissue Engineering Applications
Arguente
 João Reina Maia e Silva (Doutoramento)
Universidade de Coimbra, Portugal
2011/02/11 Process Engineering of Stem Cells for Clinical Application
Arguente principal
 Maria Margarida de Carvalho Negrão Serra (Doutoramento)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2010/01/12 Development of Structures Based on Bacterial Cellulose for the Production of Vascular Prostheses
Arguente
 Fábia Karine Andrade (Doutoramento)
Universidade do Minho, Portugal
2009/12/01 Cell-Based Microarray Systems for Stem Cell Expansion and Differentiation
Arguente
 Tiago Paulo Gonçalves Fernandes (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2008/01/12 Development and Characterization of Dextrin Based Hydrogels Use of Non-catalityc Domains for the Modification of Polysaccharides
Arguente principal
 Joana Maria Freitas Carvalho (Doutoramento)
Universidade do Minho, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2025/06/26 - 2025/06/27 3rd PNEV Meeting 2025
2020/09/13 - 2020/09/14 First Meeting of the Portuguese Network on Extracellular Vesicles Universidade do Porto
2019/10/10 - 2019/10/12 11st Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade de Lisboa
2017/10/12 - 2017/10/14 10th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade da Beira Interior
2017/02/16 - 2017/02/18 IEEE ENBENG'2017 - 5th Portuguese Meeting in Bioengineering Universidade de Coimbra
2015/10/15 - 2015/10/16 9th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade Nova de Lisboa
2013/09/08 - 2013/09/09 8th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies
2012/05/26 - 2012/05/27 7th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade do Porto
2011/04/28 - 2011/04/29 6th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade de Coimbra Centro de Neurociências e Biologia Celular
2010/05/20 - 2010/05/21 5th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade do Minho
2009/04/29 - 2009/04/30 4th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade de Lisboa Instituto Superior Tecnico
2008/04/23 - 2008/04/24 3rd Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies Universidade do Algarve

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2019/11/01 - Atual Biomaterials Science RSC
2018 - 2018 Bioconjugate Chemistry (1520-4812) American Chemical Society
2018 - 2018 Nanoscale (2040-3372) The Royal Society of Chemistry
2018 - 2018 Theranostics (1838-7640) Ivyspring International Publisher
2017 - 2018 Small (1613-6829) WILEY-VCH
2016 - 2018 Advanced Materials (1521-4095) Wiley (John Wiley & Sons)
2017 - 2017 Advanced Functional Materials (1616-3028) Wiley (John Wiley & Sons)
2016 - 2017 Journal of Controlled Release (0168-3659) Elsevier
2011 - 2017 ACS Nano (1936-086X) American Chemical Society
2013 - 2016 Biomaterials (0142-9612) Elsevier
2012 - 2015 Acta Biomaterialia (1742-7061) Elsevier
2013 - 2013 Proceedings of the National Academy of Sciences (1091-6490) Proceedings of the National Academy of Sciences
2012 - 2012 Experimental Dermatology (1600-0625) Wiley (Blackwell Publishing)
2012 - 2012 Langmuir (1520-5827) American Chemical Society
2012 - 2012 Nature Methods (1548-7105) Springer Science and Business Media LLC
2012 - 2012 PLoS ONE (1932-6203) Public Library of Science
2011 - 2011 Journal of Cardiovascular Translational Research (1937-5395) Springer-Verlag
2009 - 2011 Journal of Biomaterials Science Polymer Edition (1568-5624) Informa UK (Taylor & Francis)
2009 - 2011 Journal of Tissue Engineering and Regenerative Medicine (1932-7005) Wiley (John Wiley & Sons)
2010 - 2010 Nature Materials (1476-4660) Springer Science and Business Media LLC
2009 - 2009 Current Stem Cell Research & Therapy (1574-888X) Bentham Science
2009 - 2009 Stem Cells International (1687-9678) Hindawi Publishing Corporation (Sage-Hindawi Access to Research)
2008 - 2008 Biotechnology Progress (1520-6033) Wiley (John Wiley & Sons)
2008 - 2008 Tissue Engineering (1076-3279) Mary Ann Liebert
2001 - 2007 Biotechnology and Bioengineering (1097-0290) Wiley (John Wiley & Sons)

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2018/09/15 - 2030/09/15 Coordinator of the mandatory module (5th year; branch: biomaterials) “Regenerative Medicine” in the Integrated Master of Biomedical Engineering (Curso de mestrado (conclusão do curso de especialização)) Universidade de Coimbra, Portugal
2025/01/27 - 2030/07/31 Coordinator of the mandatory module (5th year) “Regenerative Medicine” in the Master of Cell and Molecular Biology (Mestrado)
2012/05/02 - 2022/05/02 Co-coordinator of the “Advanced Therapies” educational module (a 1 week-module per year) at the Experimental Biology and Biomedicine Program (2012- present) Universidade de Coimbra, Portugal

Tissue Engineering and Regenerative Medicine International Society, Estados Unidos
2006/05/02 - 2018/05/02 Co-coordinator of the “Cell and Tissue Engineering” educational module (a 2 week-module per year) at the MIT-Portugal Program (2006-2018) Universidade de Coimbra, Portugal

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2024/10/29 “Portuguese scientists are trying to create a way to regenerate the brain after a stroke” Journal Publico
2024/08/29 "Reinvented cells": Researchers at the University of Coimbra aim to discover new ways to overcome stroke injuries. Expresso
2021/08/03 Contribution for the article entitled "Medicina anti-envelhecimento: mito, ciencia ou futuro?" about anti-ageing strategies in Noticias Magazine. Diario Noticias
2020/12/03 Press releases about the attraction of two European projects “COVIRNA” and “RESETageing” (Twinning project) in the most important National journals such as Publico and Diario de Noticias and advertised in the radio and TV. Publico
2020/08/17 Press article about a study published in Nature Communications entitled: "Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13" Publico
2020/01/20 Article press about a study published in Angewandte Chemie entitled: “A light-activatable nanoparticle library for the controlled release of non-coding RNAs”. Publico
2018/10/18 Press article about a study published in ACS Nano entitled: “Modulation of angiogenic activity by light-activatable miRNA-loaded nanocarriers”. The article has been published in Diario de Noticias and advertised in the radio and TV. Diario de Noticias

Entrevista / Programa (rádio / tv)

Programa Tema
2017/08/04 - 2017/08/04 RTP1 ERA Chair project
2017/01/31 - 2017/01/31 Dias do Futuro, Antena 1 Premio Inovação Bluepharma
2014/01/13 - 2014/01/13 RTP1 Cientistas portugueses descobrem adesivo para reparar 'corações partidos'

Tutoria

Tópico Nome do aluno
2018/08 - Atual Cardiovascular ageing Ana Filipa Roque Branco
2018/03 - Atual Tiago Batista Abrantes Rondão
2018/02 - Atual Ines Maria Cunha Albino
2017/07 - Atual Nanomedicine Miguel Maria da Fonseca Miranda Ferreira Lino
2017/01 - Atual Nanomedicine Arnab Banerjee
2016/11 - Atual Cardiovascular ageing Patrícia Raquel Pinheiro Pitrez Pereira
2015/05 - Atual Remotely controlling gene editing in neural stem cells Susana Margarida Neto Simões
2014/08 - Atual Nanomedicine and ageing Luis Miguel Beicinha Branco Estronca
2014/04 - Atual Light-triggerable nanoparticles for non-coding RNA delivery Vitor Manuel dos Santos Francisco
2013/01 - Atual Cellular reprogramming by near infrared (NIR)-activatable nanoparticles containing transcription factors Sonia Luzia Claro de Pinho
2011/06 - Atual Differentiation of human pluripotent stem cells into endothelial cells using bioengineering tools Susana Carvalho Rosa
2017/08 - 2019/03 Nanomedicine Andreia Marques Ribeiro
2018/03 - 2018/09 Filipe Diogo Sousa Coelho
2017/06 - 2018/03 Antonio José da Silva Santinha
2017/09 - 2018/01 Mehrzad Zargarzadeh
2017/01 - 2017/12 Vanessa Pinto
2016/11 - 2017/11 Malwina Kotowicz
2016/04 - 2017/09 Bioengineering of mature cardiac constructs from human induced pluripotent stem cells (iPSC-derived) cardiomiocytes for drug screening and disease modeling Henrique Miguel Martiniano Vazão de Almeida
2015/05 - 2017/03 Stroke therapy based on exosomes Alessandra Arcoverde Cavalcanti Zonari
2017 - 2017 Supervision of short-term lab tranings for students enrolled in PhD programs Mariana Branco
2017 - 2017 Supervision of short-term lab tranings for students enrolled in PhD programs Rita Rodrigues Sá Ferreira
2016/05 - 2016/12 Nanomedicine Sandra Cristina Norte Pinto
2013/01 - 2016/08 Nanoparticles conjugated with photo-clevable linkers for the intracellular delivery of biomolecules Adrián Jiménez- Balsa
2012/09 - 2016/04 Sandra Pinto
2014/01 - 2016/01 Synthetic microparticles conjugated with VEGF165 improve the survival and function of endothelial progenitor cells via microRNA17 inhibition Sezin Aday
2014/03 - 2015/12 Enhanced diabetic wound healing by small extracellular vesicles controlled released by a light-triggerable hydrogel Renato Manuel Soares Cardoso
2015/01 - 2015/09 Tania Barata
2013/03 - 2015/06 Enhanced diabetic wound healing by small extracellular vesicles controlled released by a light-triggerable hydrogel Joana Rita Simões Correia
2012/12 - 2015/05 High-throughput identification of small molecules that affect human embryonic vascular development Helena Sofia Esmeraldo de Campos Vazão
2010/09 - 2015/05 José Miguel de Jesus Paiva
2014/01 - 2015/03 Diana Catarina Santos
2015 - 2015 Supervision of short-term lab tranings for students enrolled in PhD programs Claudia Fernandes
2014/04 - 2014/12 João Pedro Alves Lopes
2014/01 - 2014/09 João Santos
2014 - 2014 Supervision of short-term lab tranings for students enrolled in PhD programs Catarina Araujo Gomes Rebelo
2014 - 2014 Supervision of short-term lab tranings for students enrolled in PhD programs Bernardo Martins da Cunha Abecassis
2013/08 - 2013/12 Catarina Araujo Gomes Rebelo
2011/01 - 2013/12 Nanomedicine João Reina Maia e Silva
2010/03 - 2013/07 Nanomedicine Akhilesh Rai
2011/10 - 2013/05 Nanomedicine Marta Lima Evangelista
2010/06 - 2012/06 David José Roxo Botequim
2012 - 2012 Supervision of short-term lab tranings for students enrolled in PhD programs Inês Agapito Honório
2010/11 - 2011/11 Lysophosphatidic acid enhances survival of human CD34+ cells in ischemic conditions Isabel Maria Fidalgo Silva Carvalho
2009/01 - 2011/08 Nanomedicine Paula Sofia Sarrico Lacerda
2011/01 - 2011/07 Supervision of short-term lab tranings for students enrolled in PhD programs Leonardo Ricotti
2011 - 2011 Supervision of short-term lab tranings for students enrolled in PhD programs Patrícia Raquel Pinheiro Pitrez Pereira
2007/11 - 2010/11 Improved Survival, Vascular Differentiation and Wound Healing Potential of Stem Cells Co-cultured with Endothelial Cells Dora Cristina dos Santos Pedroso
2010 - 2010 Supervision of short-term lab tranings for students enrolled in PhD programs Carlos Samuel Marques Boto
2009 - 2009 Supervision of short-term lab tranings for students enrolled in PhD programs Maria Nunes Pereira
2009 - 2009 Supervision of short-term lab tranings for students enrolled in PhD programs Sezin Aday
2008 - 2008 Supervision of short-term lab tranings for students enrolled in PhD programs David Fernandes Braga Malta
Distinções

Prémio

2025 Award in Innovation granted by the University of Coimbra
2024 Award in Innovation granted by the University of Coimbra
2022 Award of Regenerative Medicine granted by Portuguese Society for Stem Cells and Cell Therapies
2020 Best poster award, XIII Spanish-Portuguese Conference on Controlled Drug Delivery, Santiago de Compostela, 2020
2018 Best poster award, EMBO advanced course in extracellular vesicles, Heidelberg, Germany, April 2018
2017 Premio de Boas Práticas de Envelhecimento Ativo e Saudável na Região Centro: Conhecimento
Comissão de Coordenação e Desenvolvimento Regional do Centro, Portugal
2017 Best poster award, Sociedade Portuguesa de Células Estaminais e Terapias Celulares, Covilhã, Portugal, October 2017
2017 Best poster award, 6th China-Europe Symposium on Biomaterials in Regenerative Medicine (CESB2017), May 21-24, 2017, Porto
2017 Best poster award, V Jornadas de Química e Bioquímica, UBI, May 3-4, 2017, Covilhã
2016 ERA-CHAIR award, project: "Enhancing research in ageing at the university of Coimbra”
European Commission Sixth Framework Programme, Bélgica
2016 Bluepharma innovation award
Bluepharma, Portugal
2016 BIG innovation award, project “NoMicro”, Lisbon, July 2016
2016 World biomaterials congress travel award, for the abstract entitled "¿Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation" (Emanuel Quartin)
2015 FCT Investigator award (“advanced grant”)
Fundação para a Ciência e a Tecnologia, Portugal
2015 Medal of Honor L´Oreal Portugal for Women in Science (11th edition)(Raquel Ferreira)
2015 Forbes Magazine as “30 under 30” in Healthcare (Maria Pereira)
2014 Bristol Cardiovascular Early career research event, to the abstract "VEGF-bound beads modulate endothelial cell survival and microRNA expression" (Sezin Aday)
2014 MIT Technology Review¿s Annual Innovators under 35 (Maria Pereira)
2013 FCT Investigator award (“development grant”)
Fundação para a Ciência e a Tecnologia, Portugal
2013 Best poster award, Dresden School on Functional Nanomaterials (Dresden, October 2013). Poster entitled: “Light-activatable polymeric nanoparticles for intracellular delivery in cancer stem cells”. (Carlos Boto)
2013 Pulido Valente Ciencia 2013 prize (Tiago Santos)
2013 Best poster award
2013 Best oral communication, Sociedade Portuguesa de Células Estaminais e Terapias Celulares for the oral communication: "A stable and reproducible human blood-brain barrier model derived from stem cells" (Sezin Aday)
2012 European Research Council- Starting Independent Researcher Grant (StG, Grant nº 307384)
2012 Science, Engineering and Technology (SET) award, Silver prize in the Biological Sciences section (UK, 2012) attributed to Renata Gomes with the work entitled: “Nanoparticles for simultaneous MRI tracking and microRNA delivery"
2011 Science communication award, Mending Broken Hearts award (British Heart Foundation) (Renata Gomes)
2011 Best oral communication, 6th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Biocant, 28 e 29 de Abril, 2011 (Tiago Santos)
2010 Best poster award, TNT Conference- Trends in nanotechnology, Braga, 2010 (Cristiana Paulo)
2010 Best oral communication, 5th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Caldas das Taipas, May 2010 (Francisca Eiriz)
2008 Crioestaminal Prize
2005 First Prize, Current Progress in Tissue Engineering Conference (MIT, Boston, Massachusetts, USA) (Jeffrey Karp)
2005 First Prize, MIT Chemical Engineering Poster Competition (Boston, Massachusetts, USA) (Jeffrey Karp)

Outra distinção

2012 Member of the Jury of Pulido Valente Ciencia 2012 prize