Luis Graca has an MD from the University of Lisbon, Portugal, and a PhD in transplant immunology from the University of Oxford, UK. He developed his post-doctoral research first in Oxford and later at the Institute for Child Health Research in Perth, Australia. He is currently Professor of Immunology and Vice-Dean at the University of Lisbon Medical School, directing a research group in Cellular Immunology at the Instituto de Medicina Molecular. My research's primary focus has been understanding the regulation of immune pathology. I acquired unique expertise with therapeutic monoclonal antibodies (under H. Waldmann) and regulatory T (Treg) cells, which I have used to study human immunology and immune pathology. Recently I made significant contributions related to the regulation of humoral responses in human individuals, and in the pathogenesis of human autoimmunity. I have been exploring the concept that in the same way that specialized inflammatory responses are necessary for optimal immunity, specialized regulatory mechanisms ought to be also present. While probing this concept, I discovered the existence of Foxp3+ iNKT cells and, more recently, T follicular regulatory (Tfr) cells specialized in regulating humoral responses. The recognition of my research has led to invitations to review the field, presentations in major conferences, election to editor-in-chief of the European Federation of Immunology Societies (EFIS) official journal, as well as election as president of the Portuguese Society of Immunology and more recently as president of the Portuguese Medical Sciences Society (the oldest medical society in Europe). Given my expertise in immunology and vaccination, I have been serving as co-chair of the National Advisory Group for COVID-19 Vaccination since 2020, representing the country in meetings of the Strategic Advisory Group on Immunization (SAGE) of the WHO, and National Immunization Technical Advisory Groups (NITAG) of the ECDC. One highlight of my career was the definition of a COVID-19 vaccination plan incorporating the best immunology evidence and transparent public communication, leading to overall population acceptance and broad vaccination coverage, recognized as one of the best vaccination programs in the World. I have been hosting several artists from different countries, including a long-term relationship with Marta de Menezes (www.martademenezes.com), a pioneer in the field of bioart. Artworks developed by different artists in collaboration with Graca's laboratory have been exhibited in major venues worldwide and included in books and articles reviewing the leading edge of science/art collaborations.

Identificação pessoal

Nome completo
Luis Ricardo Silva Graca

Nomes de citação

  • Graca, Luis

Identificadores de autor

Ciência ID
Google Scholar ID
Researcher Id
Scopus Author Id


  • 217999467 (Profissional)


  • Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Avenida Professor Egas Moniz, 1649-028, Lisbon, Lisbon, Portugal (Profissional)


Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Imunologia


Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Espanhol; Castelhano Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador independente (B2) Utilizador proficiente (C2) Utilizador proficiente (C1)
Francês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B1) Utilizador independente (B2) Utilizador independente (B1)
Grau Classificação
Habilitation (Título de Agregado)
Universidade de Lisboa Faculdade de Medicina, Portugal
"Immune tolerance" (TESE/DISSERTAÇÃO)
D.Phil. in Medical Sciences - Immunology (Doutoramento)
University of Oxford, Reino Unido
"Mechanisms of Peripheral Tolerance in Transplantation" (TESE/DISSERTAÇÃO)
Medicine (M.D.) (Licenciatura)
Universidade de Lisboa Faculdade de Medicina, Portugal
Percurso profissional


Categoria Profissional
Instituição de acolhimento
2005/03/01 - Atual Investigador principal (carreira) (Investigação) Instituto de Medicina Molecular, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
2019/11/11 - Atual Professor Catedrático (Docente Universitário) Universidade de Lisboa - Faculdade de Medicina, Portugal
Universidade de Lisboa - Faculdade de Medicina, Portugal
2013/09/10 - 2019/10/31 Professor Associado (Docente Universitário) Universidade de Lisboa - Faculdade de Medicina, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
2022/06/30 - Atual Vice-Presidente Universidade de Lisboa - Faculdade de Medicina, Portugal


Categoria Profissional
Instituição de acolhimento
2004/03/01 - 2013/08/31 Assistant Professor of Immunology Universidade de Lisboa Faculdade de Medicina, Portugal
2004/08/01 - 2005/03/31 Visiting post-doctoral Fellow at the Cell Biology Group (head: Professor Patrick G. Holt) Telethon Institute for Child Health Research, University of Western Australia, Austrália
2002/07/01 - 2004/07/30 Post-doctoral Fellow at the Therapeutic Immunology Group (head: Professor Herman Waldmann) University of Oxford - Sir William Dunn School of Pathology, Reino Unido
2002/10/01 - 2004/06/30 Lecturer (class A) in Medicine University of Oxford - St. Catherine's College, Reino Unido
2000/10/01 - 2003/06/30 Tutorials in Pathology and Immunology University of Oxford - Sir William Dunn School of Pathology, Reino Unido
1998/10/01 - 2002/06/30 PhD (DPhil) student University of Oxford - Sir William Dunn School of Pathology, Reino Unido
1997/09/01 - 1998/09/30 Gulbenkian PhD Program in Biology and Medicine Instituto Gulbenkian de Ciência, Portugal
1996/01/01 - 1997/09/01 Medical Internship Centro Hospitalar Universitário Lisboa Norte EPE, Portugal


Designação Financiadores
2023 - 2026 Modulation of human antibody responses by T follicular helper subsets
Fundação para a Ciência e Tecnologia
2023 - 2025 Reconstructing immune dysregulation leading to therapeutic resistance in Crohn’s disease
MISP 101328
Merck Sharp & Dohme UK Ltd
2022 - 2025 Harnessing germinal centre regulation for improved vaccines
Caixabank SA
2021/01/01 - 2024/12/31 Enlight-ten+: European Network Linking Informatics and Genomics of Helper T cells in tissues
Investigador responsável
Instituto de Medicina Molecular, Portugal
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Em curso
2020/03/01 - 2023/02/28 Thymic Abnormalities in Rare Immunological Diseases (TARID)
Investigador responsável
Instituto de Medicina Molecular, Portugal
European Union
Em curso
2020/10/01 - 2021/09/30 Nanomaterials to design new vaccines
Investigador responsável
Instituto de Medicina Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2020/07/09 - 2021/01/08 Immune senescence in COVID-19
Investigador responsável
Instituto de Medicina Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2020/05/15 - 2020/08/14 Repository of single cell transcriptomes of COVID-19 immune cell subsets.
Investigador responsável
Instituto de Medicina Molecular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2015/10/01 - 2019/09/30 Enlight-ten: European Network Linking Informatics and Genomics of Helper T cells comprising TEN beneficiaries
Investigador responsável
Instituto de Medicina Molecular, Portugal
2015/09 - 2018/08 Characterization of T follicular helper (Tfh) cells and B cell isotype switching induced by type 1 and type 2 adjuvants
Fundação para a Ciência e Tecnologia
2015/01 - 2017/12 Targeting germinal centre dysregulation in allergy
Fundação para a Ciência e Tecnologia
2013/04 - 2016/04 Animal models of human disease: refinement of strategies and implementation of new technologies Fundação para a Ciência e a Tecnologia, I.P.
2012/01 - 2014/12 Regulation of germinal centre reaction by Foxp3+ follicular T cells Fundação para a Ciência e a Tecnologia, I.P.
2011/01 - 2013/12 Cellular therapy for liver-specific immune suppression Fundação para a Ciência e a Tecnologia, I.P.
2010/01 - 2013/06 Tolerance induction to recombinant clotting factors in a murine model of hemophilia Fundação para a Ciência e a Tecnologia, I.P.
2009/01 - 2011/12 Invariant Natural Killer T Cells in Allergic Asthma and Tolerogenic Therapy. Fundação para a Ciência e a Tecnologia, I.P.
2007/07 - 2009/12 Co-receptor and co-stimulation blockade for the induction of regulatory T cells in allergic airways disease. Fundação para a Ciência e a Tecnologia, I.P.
2005/05 - 2007/01 Tolerance induction in autoimmunity: reprogramming the immune system with monoclonal antibodies Fundação para a Ciência e a Tecnologia, I.P.


Artigo em revista
  1. Kevin Y Yang; Jinyue Liao; Zhangjing Ma; Hung Fat Tse; Liwei Lu; Luis Graca; Kathy O Lui. "Single-cell transcriptomics of Treg reveals hallmarks and trajectories of immunological aging". Journal of Leukocyte Biology (2024): https://doi.org/10.1093/jleuko/qiad104.
  2. Gertrudis Rojas; Relova-Hernández E; Pérez-Riverón A; Castro-Martínez C; Diaz-Bravo O; Infante YC; Gómez T; et al. "Molecular reshaping of phage-displayed Interleukin-2 at beta chain receptor interface to obtain potent super-agonists with improved developability profiles.". Communications biology (2023): https://europepmc.org/articles/PMC10412584.
  3. Catarina Tomé; Filipa Oliveira Ramos; Raquel Marques Ruivo; Ana Filipa Mourão; Sousa S; Marques C; Melo AT; et al. "Children with extended oligoarticular and polyarticular juvenile idiopathic arthritis have alterations in B and T follicular cell subsets in peripheral blood and a cytokine profile sustaining B cell activation.". RMD open (2023): https://europepmc.org/articles/PMC10476142.
  4. Tiago Dias Domingues; Malato J; Anna D. Grabowska; Lee JS; Ameijeiras-Alonso J; Biecek P; Graça L; et al. "Association analysis between symptomology and herpesvirus IgG antibody concentrations in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and multiple sclerosis.". Heliyon (2023): https://europepmc.org/articles/PMC10372404.
  5. Matos AI; Peres C; Carreira B; Moura, Liane; Rita C Acúrcio; Vogel T; Wegener E; et al. "Polyoxazoline-Based Nanovaccine Synergizes with Tumor-Associated Macrophage Targeting and Anti-PD-1 Immunotherapy against Solid Tumors.". Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023): https://europepmc.org/articles/PMC10477894.
  6. Luis Graca; Ana Caetano Faria; Ruy M. Ribeiro. "Illuminating a blind spot in SARS-CoV-2 immunity". Nature Immunology (2023): https://doi.org/10.1038/s41590-023-01518-w.
  7. Luis Graca; Johanne Jacobsen; Saumya Kumar. "The expanding family of T follicular regulatory cells". Science Immunology (2023): https://doi.org/10.1126/sciimmunol.adg7526.
  8. João Malato; Luís Graça; Nuno Sepúlveda. "Impact of Misdiagnosis in Case-Control Studies of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Diagnostics (2023): https://doi.org/10.3390/diagnostics13030531.
  9. Malato J; Ribeiro RM; Fernandes E; Leite PP; Casaca P; Antunes C; Fonseca VR; Gomes MC; Graca L. "Stability of hybrid versus vaccine immunity against BA.5 infection over 8 months.". The Lancet. Infectious diseases (2023): http://europepmc.org/abstract/med/36620968.
  10. Ribeiro F; Romão VC; Rosa S; Jesus K; Água-Doce A; Barreira SC; Martins P; et al. "Different antibody-associated autoimmune diseases have distinct patterns of T follicular cell dysregulation.". Scientific reports (2022): http://europepmc.org/abstract/med/36271118.
  11. João Malato; Ruy M. Ribeiro; Pedro P. Leite; Pedro Casaca; Eugénia Fernandes; Carlos Antunes; Válter R. Fonseca; Manuel C. Gomes; Luis Graca. "Risk of BA.5 Infection among Persons Exposed to Previous SARS-CoV-2 Variants". New England Journal of Medicine 387 10 (2022): 953-954. https://doi.org/10.1056/NEJMc2209479.
  12. Carmenate T; Montalvo G; Lozada SL; Rodriguez Y; Ortiz Y; Díaz C; Avellanet J; et al. "The antitumor effect induced by an IL-2 'no-alpha' mutein depends on changes in the CD8+ T lymphocyte/Treg cell balance.". Frontiers in immunology (2022): http://europepmc.org/abstract/med/36059465.
  13. Acúrcio RC; Pozzi S; Carreira B; Pojo M; Gómez-Cebrián N; Casimiro S; Fernandes A; et al. "Therapeutic targeting of PD-1/PD-L1 blockade by novel small-molecule inhibitors recruits cytotoxic T cells into solid tumor microenvironment.". Journal for immunotherapy of cancer (2022): http://europepmc.org/abstract/med/35863821.
  14. Sepúlveda N; Malato J; Sotzny F; Grabowska AD; Fonseca A; Cordeiro C; Graça L; et al. "Revisiting IgG Antibody Reactivity to Epstein-Barr Virus in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Its Potential Application to Disease Diagnosis.". Frontiers in medicine (2022): http://europepmc.org/abstract/med/35814774.
  15. Filipa Ribeiro; Esperanza Perucha; Luis Graca. "T follicular cells: The regulators of germinal center homeostasis". Immunology Letters 244 (2022): 1-11. https://doi.org/10.1016/j.imlet.2022.02.008.
  16. Pedroso R; Ribeiro F; Pires AR; Graca L; Fonseca VR. "Identification of Human T Follicular Cells in Ectopic Lymphoid Structures.". Methods in molecular biology (Clifton, N.J.) (2022): http://europepmc.org/abstract/med/34802135.
  17. Ribeiro F; Ávila-Ribeiro P; Fonseca JE; Graca L. "Identification of Human Blood and Tissue T Follicular Regulatory (Tfr) Cells by Flow Cytometry.". Methods in molecular biology (Clifton, N.J.) (2022): http://europepmc.org/abstract/med/34802120.
  18. Malato J; Sotzny F; Bauer S; Freitag H; Fonseca A; Grabowska AD; Graça L; et al. "The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in myalgic encephalomyelitis/chronic fatigue syndrome: A meta-analysis of public DNA methylation and gene expression data.". Heliyon (2021): http://europepmc.org/abstract/med/34341773.
  19. Graca, Luis. "Developmental bifurcation of human T follicular regulatory cells.". Science immunology (2021): https://doi.org/10.1126/sciimmunol.abd8411.
  20. Graca, Luis. "Peptidylprolyl isomerase C (Ppic) regulates invariant Natural Killer T cell (iNKT) differentiation in mice.". European journal of immunology (2021): https://doi.org/10.1002/eji.202048924.
  21. Afonso P. Basto; Luis Graca. "Micro RNAs in Tfh regulation: Small molecules with a big impact". European Journal of Immunology (2021): https://doi.org/10.1002/eji.202049086.
  22. Graca, Luis. "Immunophenotype of Gastric Tumors Unveils a Pleiotropic Role of Regulatory T Cells in Tumor Development.". Cancers (2021): https://europepmc.org/articles/PMC7865950.
  23. Afonso P Basto; Luis Graca. "Regulation of antibody responses against self and foreign antigens by Tfr cells: implications for vaccine development". Oxford Open Immunology (2021): https://doi.org/10.1093/oxfimm/iqab012.
  24. Luis Graca. "The contribution of B cells to transplantation tolerance". Journal of Clinical Investigation (2020): https://doi.org/10.1172/JCI138122.
  25. Ruy M Ribeiro; Luis Graca. "Untangling the immune basis of disease susceptibility". eLife (2020): https://doi.org/10.7554/eLife.56886.
  26. Rodriguez-Barbosa, Jose-Ignacio; Schneider, Pascal; Graca, Luis; Bühler, Leo; Perez-Simon, Jose-Antonio; del Rio, Maria-Luisa. "The Role of TNFR2 and DR3 in the In Vivo Expansion of Tregs in T Cell Depleting Transplantation Regimens". International Journal of Molecular Sciences 21 9 (2020): 3347. http://dx.doi.org/10.3390/ijms21093347.
  27. Calado, Rita; Duarte, Joana; Borrego, Pedro; Marcelino, José Maria; Bártolo, Inês; Martin, Francisco; Figueiredo, Inês; et al. "A Prime-Boost Immunization Strategy with Vaccinia Virus Expressing Novel gp120 Envelope Glycoprotein from a CRF02_AG Isolate Elicits Cross-Clade Tier 2 HIV-1 Neutralizing Antibodies". Vaccines 8 2 (2020): 171. http://dx.doi.org/10.3390/vaccines8020171.
    Publicado • 10.3390/vaccines8020171
  28. Graca, Luis. "Maturation and Phenotypic Heterogeneity of Human CD4+ Regulatory T Cells From Birth to Adulthood and After Allogeneic Stem Cell Transplantation.". Frontiers in immunology (2020): https://europepmc.org/articles/PMC7848157.
  29. Graca, Luis. "Dendritic Cells Expressing MyD88 Molecule Are Necessary and Sufficient for CpG-Mediated Inhibition of IgE Production In Vivo.". Cells (2019): https://doi.org/10.3390/cells8101165.
  30. Freitas, Raquel Filipa; Basto, Afonso; Almeida, Silvia C.P.; Santos, Rita F.; Gonçalves, Carine M.; Corria-Osorio, Jesus; Carvalho, Tânia; et al. "Modulation of CD4 T cell function via CD6-targeting". EBioMedicine 47 (2019): 427-435. http://dx.doi.org/10.1016/j.ebiom.2019.08.008.
  31. Jun Deng; Yunbo Wei; Válter R. Fonseca; Luis Graca; Di Yu. "T follicular helper cells and T follicular regulatory cells in rheumatic diseases". Nature Reviews Rheumatology (2019): https://doi.org/10.1038/s41584-019-0254-2.
  32. V. R. Fonseca; L. Graca. "Contribution of FoxP3+ Tfr cells to overall human blood CXCR5+ T cells". Clinical & Experimental Immunology (2019): https://doi.org/10.1111/cei.13245.
  33. Válter R. Fonseca; Filipa Ribeiro; Luis Graca. "T follicular regulatory (Tfr) cells: Dissecting the complexity of Tfr-cell compartments". Immunological Reviews (2019): https://doi.org/10.1111/imr.12739.
  34. Rojas, Gertrudis; Carmenate, Tania; Santo-Tomás, Julio Felipe; Valiente, Pedro A.; Becker, Marlies; Pérez-Riverón, Annia; Tundidor, Yaima; et al. "Directed evolution of super-secreted variants from phage-displayed human Interleukin-2". Scientific Reports 9 1 (2019): http://dx.doi.org/10.1038/s41598-018-37280-5.
  35. Stebegg, Marisa; Kumar, Saumya D.; Silva-Cayetano, Alyssa; Fonseca, Valter R.; Linterman, Michelle A.; Graca, Luis. "Regulation of the Germinal Center Response". Frontiers in Immunology 9 (2018): http://dx.doi.org/10.3389/fimmu.2018.02469.
  36. Romão, Vasco C.; Fonseca, João Eurico; Agua-Doce, Ana; Graca, Luis. "T Follicular Regulatory Cells Are Decreased in Patients With Established Treated Rheumatoid Arthritis With Active Disease: Comment on the Article by Liu et al". Arthritis & Rheumatology 70 11 (2018): 1893-1895. http://dx.doi.org/10.1002/art.40586.
  37. Fonseca, Valter R.; Romão, Vasco C.; Fonseca, João Eurico; Agua-Doce, Ana; Graca, Luis. "Two independent studies show blood follicular T cell subsets allow the stratification of Sjögren's syndrome patients". Arthritis & Rheumatology 70 8 (2018): 1355-1356. http://dx.doi.org/10.1002/art.40487.
  38. Carmenate, Tania; Ortíz, Yaquelín; Enamorado, Michel; García-Martínez, Karina; Avellanet, Janet; Moreno, Ernesto; Graça, Luis; León, Kalet. "Blocking IL-2 Signal In Vivo with an IL-2 Antagonist Reduces Tumor Growth through the Control of Regulatory T Cells". The Journal of Immunology 200 10 (2018): 3475-3484. http://dx.doi.org/10.4049/jimmunol.1700433.
  39. Fonseca, Valter R.; Romão, Vasco C.; Agua-Doce, Ana; Santos, Mara; López-Presa, Dolores; Ferreira, Ana Cristina; Fonseca, João Eurico; Graca, Luis. "The Ratio of Blood T Follicular Regulatory Cells to T Follicular Helper Cells Marks Ectopic Lymphoid Structure Formation While Activated Follicular Helper T Cells Indicate Disease Activity in Primary Sjögren's Syndrome". Arthritis & Rheumatology 70 5 (2018): 774-784. http://dx.doi.org/10.1002/art.40424.
  40. Ana Agua-Doce; Marta Caridade; Vanessa G. Oliveira; Lisa Bergman; Maria C. Lafaille; Juan J. Lafaille; Jocelyne Demengeot; Luis Graca. "Route of Antigen Presentation Can Determine the Selection of Foxp3-Dependent or Foxp3-Independent Dominant Immune Tolerance". The Journal of Immunology 200 1 (2018): 101-109. https://doi.org/10.4049/jimmunol.1601886.
  41. Ana Raquel Maceiras; Valter R. Fonseca; Ana Agua-Doce; Luis Graca. "T follicular regulatory cells in mice and men". Immunology (2017): https://doi.org/10.1111%2Fimm.12774.
  42. Fonseca, Valter R.; Agua-Doce, Ana; Maceiras, Ana Raquel; Pierson, Wim; Ribeiro, Filipa; Romão, Vasco C.; Pires, Ana Rita; et al. "Human blood T fr cells are indicators of ongoing humoral activity not fully licensed with suppressive function". Science Immunology 2 14 (2017): eaan1487. http://dx.doi.org/10.1126/sciimmunol.aan1487.
  43. Barcia, Rita N.; Santos, Jorge M.; Teixeira, Mariana; Filipe, Mariana; Pereira, Ana Rita S.; Ministro, Augusto; Agua-Doce, Ana; et al. "Umbilical cord tissue-derived mesenchymal stromal cells maintain immunomodulatory and angiogenic potencies after cryopreservation and subsequent thawing". Cytotherapy 19 3 (2017): 360-370. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000394730300003&KeyUID=WOS:000394730300003.
  44. Peres, Carina; Matos, Ana I.; Conniot, Joao; Sainz, Vanessa; Zupancic, Eva; Silva, Joana M.; Graca, Luis; et al. "Poly(lactic acid)-based particulate systems are promising tools for immune modulation". Acta Biomaterialia 48 (2017): 41-57. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000393247000003&KeyUID=WOS:000393247000003.
  45. Almeida, Silvia C P; Graca, Luis. "IL-9 Production by Nonconventional T helper Cells.". Methods in molecular biology (Clifton, N.J.) 1585 (2017): 93-109. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:28477190&KeyUID=MEDLINE:28477190.
  46. Maceiras, Ana Raquel; Paiva Almeida, Silvia Cristina; Mariotti-Ferrandiz, Encarnita; Chaara, Wahiba; Jebbawi, Fadi; Six, Adrien; Hori, Shohei; et al. "T follicular helper and T follicular regulatory cells have different TCR specificity". Nature Communications 8 (2017): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000399984000001&KeyUID=WOS:000399984000001.
  47. Graca, Luis. "In vivo delivery of peptides and Toll-like receptor ligands by mannose-functionalized polymeric nanoparticles induces prophylactic and therapeutic anti-tumor immune responses in a melanoma model". Journal of Controlled Release (2015):
  48. Maceiras, Ana Raquel; Graca, Luis. "Identification of foxp3(+) T follicular regulatory (tfr) cells by flow cytometry.". Methods in molecular biology (Clifton, N.J.) 1291 (2015): 143-50. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:25836308&KeyUID=MEDLINE:25836308.
  49. Monteiro, Marta; Agua-Doce, Ana; Almeida, Catarina F.; Fonseca-Pereira, Diogo; Veiga-Fernandes, Henrique; Graca, Luis. "IL-9 Expression by Invariant NKT Cells Is Not Imprinted during Thymic Development". Journal of Immunology 195 7 (2015): 3463-3471. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000361741200051&KeyUID=WOS:000361741200051.
  50. Graca, Luis. "Transplantation tolerance: Context matters". European Journal of Immunology 45 7 (2015): 1921-1925. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000357687700006&KeyUID=WOS:000357687700006.
  51. Bárcia, R. N.; Santos, J. M.; Filipe, M.; Teixeira, M.; Martins, J. P.; Almeida, J.; Água-Doce, A.; et al. "What Makes Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells Superior Immunomodulators When Compared to Bone Marrow Derived Mesenchymal Stromal Cells?". Stem Cells International 2015 (2015): 1-14. http://dx.doi.org/10.1155/2015/583984.
  52. Silva, Joana M.; Vandermeulen, Gaelle; Oliveira, Vanessa G.; Pinto, Sandra N.; Rodrigues, Catarina; Salgado, Ana; Afonso, Carlos A.; et al. "Development of functionalized nanoparticles for vaccine delivery to dendritic cells: a mechanistic approach". Nanomedicine 9 17 (2014): 2639-2656.
  53. Martins, Jose Paulo; Santos, Jorge Miguel; de Almeida, Joana Marto; Filipe, Mariana Alves; Teixeira de Almeida, Mariana Vargas; Paiva Almeida, Silvia Cristina; Agua-Doce, Ana; et al. "Towards an advanced therapy medicinal product based on mesenchymal stromal cells isolated from the umbilical cord tissue: quality and safety data". Stem Cell Research & Therapy 5 (2014):
  54. Monteiro, Marta; Graca, Luis. "iNKT Cells: Innate Lymphocytes with a Diverse Response". Critical Reviews in Immunology 34 1 (2014): 81-90. http://dx.doi.org/10.1615/critrevimmunol.2014010088.
  55. Caridade, M.; Oliveira, V.G.; Agua-Doce, A.; Graca, L.; Ribeiro, R.M.. "The fate of CD4+ T cells under tolerance-inducing stimulation: a modeling perspective". Immunology and Cell Biology (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84885825144&partnerID=MN8TOARS.
  56. Monteiro, M.; Graca, L.. "Response to Comment on "Induced IL-17-producing invariant NKT cells require activation in presence of TGF-ß and IL-1ß"". Journal of Immunology 190 12 (2013): 5910-5911. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879119919&partnerID=MN8TOARS.
  57. Moura, R.A.; Canhão, H.; Polido-Pereira, J.; Rodrigues, A.M.; Navalho, M.; Mourão, A.F.; Resende, C.; et al. "BAFF and TACI gene expression are increased in patients with untreated very early rheumatoid arthritis". Journal of Rheumatology 40 8 (2013): 1293-1302. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881462125&partnerID=MN8TOARS.
  58. Santos, J.M.; Bárcia, R.N.; Simões, S.I.; Gaspar, M.M.; Calado, S.; Água-Doce, A.; Almeida, S.C.P.; et al. "The role of human umbilical cord tissue-derived mesenchymal stromal cells (UCX®) in the treatment of inflammatory arthritis". Journal of Translational Medicine 11 1 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84872268288&partnerID=MN8TOARS.
  59. Oliveira, V.G.; Agua-Doce, A.; Curotto de Lafaille, M.A.; Lafaille, J.J.; Graca, L.. "Adjuvant facilitates tolerance induction to factor VIII in hemophilic mice through a Foxp3-independent mechanism that relies on IL-10.". Blood 121 19 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84880459064&partnerID=MN8TOARS.
  60. Monteiro, M.; Almeida, C.F.; Agua-Doce, A.; Graca, L.. "Induced IL-17-producing invariant NKT cells require activation in presence of TGF-ß and IL-1ß". Journal of Immunology 190 2 (2013): 805-811. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872175916&partnerID=MN8TOARS.
  61. Caridade, Marta; Graca, Luis; Ribeiro, Ruy M.. "Mechanisms Underlying CD4+ Treg Immune Regulation in the Adult: From Experiments to Models". Frontiers in Immunology 4 (2013): http://dx.doi.org/10.3389/fimmu.2013.00378.
  62. Graca, Luis. "Regulatory T cells and the control of the allergic response". J Allergy (2012):
  63. Duarte, J.; Carrié, N.; Oliveira, V.G.; Almeida, C.; Agua-Doce, A.; Rodrigues, L.; Simas, J.P.; Mars, L.T.; Graca, L.. "T cell apoptosis and induction of foxp3 + regulatory T cells underlie the therapeutic efficacy of CD4 blockade in experimental autoimmune encephalomyelitis". Journal of Immunology 189 4 (2012): 1680-1688. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864827341&partnerID=MN8TOARS.
  64. Moura, R.A.; Graca, L.; Fonseca, J.E.. "To B or not to B the conductor of rheumatoid arthritis orchestra". Clinical Reviews in Allergy and Immunology 43 3 (2012): 281-291. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871664898&partnerID=MN8TOARS.
  65. Duarte, J.; Caridade, M.; Graca, L.. "CD4-blockade can induce protection from peanut-induced anaphylaxis". Frontiers in Immunology 2 OCT (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-84864813649&partnerID=MN8TOARS.
  66. Agua-Doce, A.; Graca, L.. "Prevention of house dust mite induced allergic airways disease in mice through immune tolerance". PLoS ONE 6 7 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-79960790263&partnerID=MN8TOARS.
  67. Wollenberg, I.; Agua-Doce, A.; Hernández, A.; Almeida, C.; Oliveira, V.G.; Faro, J.; Graca, L.. "Regulation of the germinal center reaction by Foxp3 + follicular regulatory T cells". Journal of Immunology 187 9 (2011): 4553-4560. http://www.scopus.com/inward/record.url?eid=2-s2.0-80555133319&partnerID=MN8TOARS.
  68. Moura, R.A.; Cascão, R.; Perpétuo, I.; Canhão, H.; Vieira-sousa, E.; Mourão, A.F.; Rodrigues, A.M.; et al. "Cytokine pattern in very early rheumatoid arthritis favours B-cell activation and survival". Rheumatology 50 2 (2011): 278-282. http://www.scopus.com/inward/record.url?eid=2-s2.0-78751692218&partnerID=MN8TOARS.
  69. Oliveira, V.G.; Caridade, M.; Paiva, R.S.; Demengeot, J.; Graca, L.. "Sub-optimal CD4+ T-cell activation triggers autonomous TGF-ß-dependent conversion to Foxp3+ regulatory T cells". European Journal of Immunology 41 5 (2011): 1249-1255. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952915024&partnerID=MN8TOARS.
  70. Graca, Luis. "Modulation of synovial IL-17 and Foxp3 expression in the prevention of autoimmune arthritis". PLoS ONE (2010):
  71. Curotto de Lafaille, M.A.; Lafaille, J.J.; Graça, L.. "Mechanisms of tolerance and allergic sensitization in the airways and the lungs". Current Opinion in Immunology 22 5 (2010): 616-622. http://www.scopus.com/inward/record.url?eid=2-s2.0-78049309522&partnerID=MN8TOARS.
  72. Cascão, R.; Moura, R.A.; Perpétuo, I.; Canhão, H.; Vieira-Sousa, E.; Mourão, A.F.; Rodrigues, A.M.; et al. "Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis". Arthritis Research and Therapy 12 5 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77958006636&partnerID=MN8TOARS.
  73. Monteiro, M.; Almeida, C.F.; Caridade, M.; Ribot, J.C.; Duarte, J.; Agua-Doce, A.; Wollenberg, I.; Silva-Santos, B.; Graca, L.. "Identification of regulatory Foxp3+ invariant NKT cells induced by TGF-ß". Journal of Immunology 185 4 (2010): 2157-2163. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956943528&partnerID=MN8TOARS.
  74. Raposo, B.R.; Rodrigues-Santos, P.; Carvalheiro, H.; Água-Doce, A.M.; Carvalho, L.; Pereira Da Silva, J.A.; Graça, L.; Souto-Carneiro, M.M.. "Monoclonal anti-CD8 therapy induces disease amelioration in the K/BxN mouse model of spontaneous chronic polyarthritis". Arthritis and Rheumatism 62 10 (2010): 2953-2962. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957678588&partnerID=MN8TOARS.
  75. Caetano-Lopes, J.; Nery, A.M.; Canhão, H.; Duarte, J.; Cascão, R.; Rodrigues, A.; Perpétuo, I.P.; et al. "Chronic arthritis leads to disturbances in the bone collagen network". Arthritis Research and Therapy 12 1 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77649302076&partnerID=MN8TOARS.
  76. Moura, R.A.; Weinmann, P.; Pereira, P.A.; Caetano-Lopes, J.; Canhão, H.; Sousa, E.; Mourão, A.F.; et al. "Alterations on peripheral blood B-cell subpopulations in very early arthritis patients". Rheumatology 49 6 (2010): 1082-1092. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953487867&partnerID=MN8TOARS.
  77. Mancuso, M.E.; Graca, L.; Auerswald, G.; Santagostino, E.. "Haemophilia care in children - Benefits of early prophylaxis for inhibitor prevention". Haemophilia 15 SUPPL. 1 (2009): 8-14. http://www.scopus.com/inward/record.url?eid=2-s2.0-62149132517&partnerID=MN8TOARS.
  78. Caetano-Lopes, J.; Nery, A.M.; Henriques, R.; Canhão, H.; Duarte, J.; Amaral, P.M.; Vale, M.; et al. "Chronic arthritis directly induces quantitative and qualitative bone disturbances leading to compromised biomechanical properties". Clinical and Experimental Rheumatology 27 3 (2009): 475-482. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349116274&partnerID=MN8TOARS.
  79. Graca, L.. "CTLA4Ig and the therapeutic potential of T cell co-stimultion blockade | CTLA4Ig e o potencial terapêutico do bloqueio da co-estimulação das células T". Acta Reumatologica Portuguesa 33 3 (2008): 267-276. http://www.scopus.com/inward/record.url?eid=2-s2.0-58849120142&partnerID=MN8TOARS.
  80. Moura, R.; Água-Doce, A.; Weinmann, P.; Graça, L.; Fonseca, J.E.. "B cells: From the bench to the clinical practice". Acta Reumatologica Portuguesa 33 2 (2008): 137-154. http://www.scopus.com/inward/record.url?eid=2-s2.0-53749095047&partnerID=MN8TOARS.
  81. Água-Doce, A.; Graça, L.. "Induction of dominant tolerance using monoclonal antibodies". Methods in Molecular Biology 380 (2007): 405-429. http://www.scopus.com/inward/record.url?eid=2-s2.0-36549008540&partnerID=MN8TOARS.
  82. Oliveira, V.; Água-Doce, A.; Duarte, J.; Soares, M.P.; Graca, L.. "Regulatory T cell maintenance of dominant tolerance: Induction of tissue self-defense?". Transplant Immunology 17 1 (2006): 7-10. http://www.scopus.com/inward/record.url?eid=2-s2.0-35748956936&partnerID=MN8TOARS.
  83. Graca, L.; Waldmann, H.. "Reprogramming the immune system using antibodies.". Methods in molecular biology (Clifton, N.J.) 333 (2006): 247-268. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746450135&partnerID=MN8TOARS.
  84. Cobbold, S.P.; Adams, E.; Graca, L.; Daley, S.; Yates, S.; Paterson, A.; Robertson, N.J.; et al. "Immune privilege induced by regulatory T cells in transplantation tolerance". Immunological Reviews 213 1 (2006): 239-255. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748743615&partnerID=MN8TOARS.
  85. Graça, L.; Silva-Santos, B.; Coutinho, A.. "The blind-spot of regulatory T cells". European Journal of Immunology 36 4 (2006): 802-805. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645938618&partnerID=MN8TOARS.
  86. Graca, L.; Daley, S.; Fairchild, P.J.; Cobbold, S.P.; Waldmann, H.. "Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning". BMC Immunology 7 (2006): http://www.scopus.com/inward/record.url?eid=2-s2.0-33646671989&partnerID=MN8TOARS.
  87. Waldmann, H.; Chen, T.-C.; Graca, L.; Adams, E.; Daley, S.; Cobbold, S.; Fairchild, P.J.. "Regulatory T cells in transplantation". Seminars in Immunology 18 2 (2006): 111-119. http://www.scopus.com/inward/record.url?eid=2-s2.0-32644478231&partnerID=MN8TOARS.
  88. Waldmann, H.; Graca, L.; Adams, E.; Fairchild, P.; Cobbold, S.. "Regulatory T cells in transplantation tolerance". Current Topics in Microbiology and Immunology 293 (2005): 249-264. http://www.scopus.com/inward/record.url?eid=2-s2.0-20344369543&partnerID=MN8TOARS.
  89. Benghiat, F.S.; Graca, L.; Braun, M.Y.; Detienne, S.; Moore, F.; Buonocore, S.; Flamand, V.; et al. "Critical influence of natural regulatory CD25+ T cells on the fate of allografts in the absence of immunosuppression". Transplantation 79 6 (2005): 648-654. http://www.scopus.com/inward/record.url?eid=2-s2.0-20144386868&partnerID=MN8TOARS.
  90. Graca, L.. "New tools to identify regulatory T cells". European Journal of Immunology 35 6 (2005): 1678-1680. http://www.scopus.com/inward/record.url?eid=2-s2.0-20844449950&partnerID=MN8TOARS.
  91. Graca, L.; Chen, T.-C.; Moine, A.L.; Cobbold, S.P.; Howie, D.; Waldmann, H.. "Dominant tolerance: Activation thresholds for peripheral generation of regulatory T cells". Trends in Immunology 26 3 (2005): 130-135. http://www.scopus.com/inward/record.url?eid=2-s2.0-14644388075&partnerID=MN8TOARS.
  92. Graca, L.; Le Moine, A.; Lin, C.-Y.; Fairchild, P.J.; Cobbold, S.P.; Waldmann, H.. "Donor-specific transplantation tolerance: The paradoxical behavior of CD4+CD25+ T cells". Proceedings of the National Academy of Sciences of the United States of America 101 27 (2004): 10122-10126. http://www.scopus.com/inward/record.url?eid=2-s2.0-3042800728&partnerID=MN8TOARS.
  93. Waldmann, H.; Graca, L.; Cobbold, S.; Adams, E.; Tone, M.; Tone, Y.. "Regulatory T cells and organ transplantation". Seminars in Immunology 16 2 (2004): 119-126. http://www.scopus.com/inward/record.url?eid=2-s2.0-1242295283&partnerID=MN8TOARS.
  94. Cobbold, S.P.; Castejon, R.; Adams, E.; Zelenika, D.; Graca, L.; Humm, S.; Waldmann, H.. "Induction of foxP3+ Regulatory T Cells in the Periphery of T Cell Receptor Transgenic Mice Tolerized to Transplants". Journal of Immunology 172 10 (2004): 6003-6010. http://www.scopus.com/inward/record.url?eid=2-s2.0-2442425262&partnerID=MN8TOARS.
  95. Graca, L.; Le Moine, A.; Cobbold, S.P.; Waldmann, H.. "Antibody-Induced Transplantation Tolerance: The Role of Dominant Regulation". Immunologic Research 28 3 (2003): 181-191. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141713778&partnerID=MN8TOARS.
  96. Graca, L.; Le Moine, A.; Cobbold, S.P.; Waldmann, H.. "Dominant transplantation tolerance: Opinion". Current Opinion in Immunology 15 5 (2003): 499-506. http://www.scopus.com/inward/record.url?eid=2-s2.0-0141629548&partnerID=MN8TOARS.
  97. Fairchild, P.J.; Nolan, K.F.; Cartland, S.; Graça, L.; Waldmann, H.. "Stable lines of genetically modified dendritic cells from mouse embryonic stem cells". Transplantation 76 3 (2003): 606-608. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042967965&partnerID=MN8TOARS.
  98. Cobbold, S.P.; Adams, E.; Graca, L.; Waldmann, H.. "Serial analysis of gene expression provides new insights into regulatory T cells". Seminars in Immunology 15 4 (2003): 209-214. http://www.scopus.com/inward/record.url?eid=2-s2.0-0842281753&partnerID=MN8TOARS.
  99. Cobbold, S.P.; Nolan, K.F.; Graca, L.; Castejon, R.; Le Moine, A.; Frewin, M.; Humm, S.; et al. "Regulatory T cells and dendritic cells in transplantation tolerance: Molecular markers and mechanisms". Immunological Reviews 196 (2003): 109-124. http://www.scopus.com/inward/record.url?eid=2-s2.0-10744226541&partnerID=MN8TOARS.
  100. Cobbold, S.P.; Graca, L.; Lin, C.-Y.; Adams, E.; Waldmann, H.. "Regulatory T cells in the induction and maintenance of peripheral transplantation tolerance". Transplant International 16 2 (2003): 66-75. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037783493&partnerID=MN8TOARS.
  101. Graca, L.; Cobbold, S.P.; Waldmann, H.. "Identification of regulatory T cells in tolerated allografts". Journal of Experimental Medicine 195 12 (2002): 1641-1646. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037124359&partnerID=MN8TOARS.
  102. Lin, C.-Y.; Graca, L.; Cobbold, S.P.; Waldmann, H.. "Dominant transplantation tolerance impairs CD8+ T cell function but not expansion". Nature Immunology 3 12 (2002): 1208-1213. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036911130&partnerID=MN8TOARS.
  103. Zelenika, D.; Adams, E.; Humm, S.; Graca, L.; Thompson, S.; Cobbold, S.P.; Waldmann, H.. "Regulatory T cells overexpress a subset of Th2 gene transcripts". Journal of Immunology 168 3 (2002): 1069-1079. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036467347&partnerID=MN8TOARS.
  104. Graca, L.; Thompson, S.; Lin, C.-Y.; Adams, E.; Cobbold, S.P.; Waldmann, H.. "Both CD4+CD25+ and CD4+CD25- regulatory cells mediate dominant transplantation tolerance". Journal of Immunology 168 11 (2002): 5558-5565. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036604283&partnerID=MN8TOARS.
  105. Graca, L.; Honey, K.; Adams, E.; Cobbold, S.P.; Waldmann, H.. "Cutting edge: Anti-CD154 therapeutic antibodies induce infectious transplantation tolerance". Journal of Immunology 165 9 (2000): 4783-4786. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034327171&partnerID=MN8TOARS.
  106. Fairchild, P.J.; Brook, F.A.; Gardner, R.L.; Graça, L.; Strong, V.; Tone, Y.; Tone, M.; Nolan, K.F.; Waldmann, H.. "Directed differentiation of dendritic cells from mouse embryonic stem cells". Current Biology 10 23 (2000): 1515-1518. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034735918&partnerID=MN8TOARS.
  107. Graca, L.; Nery, S.; Bettencourt Dias, M.; Magalhaes, T.. "Weak euro hits PhDs too [2]". Nature 408 6812 (2000): http://www.scopus.com/inward/record.url?eid=2-s2.0-0034735796&partnerID=MN8TOARS.
  108. Pereira Da Silva, J.A.; Fonseca, J.E.; Graça, L.; Moita, L.; Carmo-Fonseca, M.. "Reinnervation of post-arthritic joints in the rat". Clinical and Experimental Rheumatology 14 1 (1996): 43-51. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029878532&partnerID=MN8TOARS.
Capítulo de livro
  1. João Malato; Luís Graça; Nuno Sepúlveda. "Impact of Misclassification and Imperfect Serological Tests in Association Analyses of ME/CFS Applied to COVID-19 Data". 2022.
  1. Nuno Sepúlveda; João Malato; Franziska Sotzny; Anna D Grabowska; André Fonseca; Clara Cordeiro; Luís Graça; et al. "Revisiting IgG antibody reactivity to Epstein-Barr virus in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and its potential application to disease diagnosis". 2022. https://doi.org/10.1101/2022.04.20.22273990.
  2. João Malato; Luís Graça; Nuno Sepúlveda. "Impact of imperfect diagnosis in ME/CFS association studies". 2022. https://doi.org/10.1101/2022.06.08.22276100.
  3. João Malato; Ruy M. Ribeiro; Eugénia Fernandes; Pedro Pinto Leite; Pedro Casaca; Carlos Antunes; Válter R. Fonseca; Manuel Carmo Gomes; Luis Graca. "Rapid waning of protection induced by prior BA.1/BA.2 infection against BA.5 infection". 2022. https://doi.org/10.1101/2022.08.16.22278820.
  4. João Malato; Ruy M. Ribeiro; Pedro Pinto Leite; Pedro Casaca; Eugénia Fernandes; Carlos Antunes; Válter R. Fonseca; Manuel Carmo Gomes; Luis Graca. "Risk of BA.5 infection in individuals exposed to prior SARS-CoV-2 variants". 2022. https://doi.org/10.1101/2022.07.27.22277602.


Outra produção
  1. The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: analysis of high-throughput epigenetic and gene expression studies. 2021. João Malato; Franziska Sotzny; Sandra Bauer; Helma Freitag; André Fonseca; Anna D Grabowska; Luís Graça; et al. https://doi.org/10.1101/2021.03.23.21254175.
  2. Statistical challenges of investigating a disease with a complex diagnosis. 2021. João Malato; Luís Graça; Luís Nacul; Eliana Lacerda; Nuno Sepúlveda. https://doi.org/10.1101/2021.03.19.21253905.

Arbitragem científica em conferência

Nome da conferência Local da conferência
2019/10/01 - Atual European Congress of Immunology 2021 European Federation of Immunology Societies (EFIS)

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2005/12/01 - Atual ACTIVITIES - ACADEMIC: • 2019- Member of the Scientific Council, Faculty of Medicine, Universidade de Lisboa (FMUL) • 2017- Member of the Academic Council, FMUL • 2017-18 Member of the Scientific Council, • 2013- Board Member, IMM PhD Program (Lisbon BioMed) • 2016- Member of the General Assembly of IMM (in representation of the researchers) • 2014-17 Member of Conselho de Escola (Supervisory Council), FMUL • 2009-14 Member of the Scientific Council, FMUL • 2006- Member of several committees at IMM (flow cytometry, animal house, seminars,..
2005/11/01 - Atual ACTIVITIES - SCIENCE: Journal editor: Journal of Immunology, Frontiers of Immunology (official journal of IUIS - international union of immunology societies). Reviewer of grants: ERC, MRC, Inserm, AICR, NH-MRC, among others. Reviewer for scientific journals: Cell, Science, Immunity, Nature Immunol, Nature Commun, Science Immunol, PNAS, J Exp Med, J Clin Invest, Blood,... Organization of international conferences: Portugal, Spain, France. Invited speaker: major conferences and academic institutions in all continents except Africa & Antarctica.
2005/10/01 - Atual ACTIVITY - SCIENCE COMMUNICATION: Active participation in activities to increase scientific literacy, especially among young people. This has included open days, public lectures, and appearances in the media (radio, television and printed press). Long-standing collaboration with visual artists interested in developing artworks exploring the interface between art and biomedical sciences.
2005/09/01 - Atual ACTIVITY - ART & SCIENCE: Graca has hosted over 10 visual artists in the lab over the years, and participated in collaborative artworks with artist Marta de Menezes subsequently exhibited internationally. Graca was scientific advisor for several cultural initiatives including Guimarães European Capital of Culture, international art-science festivals and conferences, and authored several articles on art and biology.

Membro de associação

Nome da associação Tipo de participação
2021/01/01 - Atual Editor-in-Chief of Immunology Letters - the official journal of EFIS (European Federation of Immunology Societies) Editor-in-Chief
2017/10/01 - Atual President of the Medical Sciences Society of Lisbon (Sociedade das Ciências Médicas de Lisboa). This is the oldest medical society in Europe, established in 1822. President
2015/07/01 - 2018/06/30 President of the Portuguese Society for Immunology (Sociedade Portuguesa de Imunologia) President

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2020/08/01 - Atual Co-coordinator - Experts Commission on COVID-19 Vaccines (definition of the national COVID-19 vaccination plan).
Direção Geral da Saúde, Portugal
2020/01/10 - Atual Experts Commission of COVID-19 testing
Direção Geral da Saúde, Portugal
2013/07/01 - 2016/06/30 Board of scientific counselors for Health Sciences (Conselho científico para as ciências da vida e saúde).
Fundação para a Ciência e Tecnologia, Portugal


2023 Pfizer Award in Clinical Research
2019 Prémio de Investigação U. Lisboa / Caixa Geral de Depósitos (Research Excelence Award)
2019 Prémio de Mérito em Saúde
Câmara Municipal de Odemira, Portugal
2017 iMM Innovators Award
2011 NEDAI Prize in Autoimmunity Research
2010 BES - National Innovation Prize in Health Sciences
Banco Espírito Santo e Comercial de Lisboa, Portugal
2009 CSL Behring - Prof. Heimburger Award

Outra distinção

2009 McCombs School of Business Global Championship at the Idea to Product® 2009 competition, 2nd place in the international final.
2004 Travel Award
Federation Of Clinical Immunology Societies, Estados Unidos
2004 Travel Award
2003 Travel Award
Federation Of Clinical Immunology Societies, Estados Unidos
2002 Best Poster Award
2001 Junior Research Fellowship
1997 PhD Scholarship
1995 Pfizer Research Award