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Guillermin Agüero Chapin. Auxiliary Researcher (PhD) at CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto (UP), Portugal (2018-up to the present). Majored in Pharmaceutical Sciences (1998) at the Universidad Central de Las Villas (UCLV), (Cuba & Spain). Master degree (2009) in Biochemistry from the Medicine School "Dr. Zerafin de Zarate Ruiz", Cuba (Excellent). PhD in Biology awarded with honours by UP, Portugal (2009-2013). The PhD thesis was focused on the development of graphical-numerical method called TI2BioP for detecting remote functional and evolutionary signals in gene/protein/peptide classes of interest for drug discovery. Postdoc fellow (2014-2018) funded by the FCT at CIIMAR, UP, in the topic: "EvoNeering: An Evolutionary Platform to Engineer the Synthesis of Bioactive Peptides" that leveraged previous expertise in alignment-free (AF) methodologies to unravel enzymatic activities of ancestral A-domains and how they could be used for innovating bioactive peptides. My overall research expertise has been related to the (i) molecular biology and genetic engineering techniques applied to plant and microbial biotechnology (ii) chemo/bioinformatics applied to drug discovery/design, (iii) machine learning and big data-based classifiers (iv) integration of heterogeneous data and algorithms to address evolutionary topics (v) complex networks to analyse/predict AMP classes. The research in these areas and the stays at Universities from Italy, Belgium, Spain, Ecuador; Mexico, Cuba and Portugal motivated my current research interest: The integration of Omics Data from Marine Invertebrates and Screening Tools to Unveil promising AMPs to develop a Next Generation of Antibiotics. My research experience is mainly gathered in 46 publications in the WoS (20 in the last 5 years), 90% of them are placed in Q1 peer-reviewed journals that have received > 660 citations (h-index of 12). In the last 5 years, have been first and corresponding author in 16 and 6 papers, respectively. Have two books published (1) ¿Alignment-Free Models in Plant Genomics (2010)¿ at Nova Science Publishers, USA and (2) Computational Approaches in Discovery & Design of Antimicrobial Peptides (2023)¿ at the MDPI publisher (Switzerland). Have attended to > 30 scientific conferences either by oral invitation or poster presentation. Recently has been scientific member and chairperson of the sessions in MOL2NET online conference (2020-2024). Guest Editor in the Current Topics in Medicinal Chemistry (2015), Antibiotics (2021-2024) and Frontiers in Bioinformatics (2022-2024) journals and received the Annual Award of the Cuban Academy of Sciences (2015). Co-directed PhD and MSc. theses on orthologs detection (2016) and new algorithms for functional enzyme classification (2021), respectively. Currently, I am co-supervising two PhD theses: (i) Computational Intelligence at the Computer Science Department of the University of Granada, Spain, and (ii) Sea Venoms: molecular and ecological innovations of cnidarians and mollusks at Biology program of FCUP (U. Porto). In the last 5 years, have participated in 4 FCT projects being Co-PI in the PTDC/CTA-AMB/31774/2017 project and PI at the COB 2023 project entitled "Computer-Aided Search for Next Generation Antibiotics from Cephalopods' Salivary Glands Proteomes", recently funded by CIIMAR with 10 000¿. Have attended in Academic Boards in Portugal (Master, 2021), Spain and Italy (PhD, 2022-2023, 2022). Member of the Topic and Reviewer Board in Marine Drugs and Antibiotics Journals (2020-2024). Reviewer of prestigious journals like Scientific Reports, BMC Bioinformatics and J. Proteome Res.; and evaluator of national projects in Ecuador and Chile. My current research interest is in the field of discovery/design of peptide drugs assisted by classical and emerging computational tools from marine sources.
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Identificação

Identificação pessoal

Nome completo
Guillermin Agüero Chapin

Nomes de citação

  • Agüero-Chapin, G

Identificadores de autor

Ciência ID
6A1E-E706-A0F1
ORCID iD
0000-0002-9908-2418
Google Scholar ID
user=3_E35bkAAAAJ&hl
Researcher Id
C-8067-2019
Scopus Author Id
57194289684

Endereços de correio eletrónico

  • gchapin@ciimar.up.pt (Profissional)

Telefones

Telefone
  • 223401800 (Profissional)

Moradas

  • Terminal de Cruzeiros de Leixões. Av. General Norton de Matos s/n, Matosinhos, 4450-208, Porto, Matosinhos, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências Exatas - Ciências da Computação e da Informação - Bioinformática
  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Médicas e da Saúde - Medicina Básica - Química Médica
  • Ciências da Engenharia e Tecnologias - Biotecnologia Industrial - Biocombustíveis
  • Ciências Agrárias - Biotecnologia Agrária e Alimentar - Biotecnologia Agrária e Biotecnologia Alimentar

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Espanhol; Castelhano (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Português Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Formação
Grau Classificação
2014/04 - 2018/08
Concluído
 An Evolution-Based Framework to Engineer the Synthesis of Biologically Active Oligopeptides (Pós-doutoramento)
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2013/11/07
Concluído
 Programa Doutoral em Biologia, UP (Doutoramento)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
"A Graphical and Numerical Approach for Functional Annotation and Phylogenetic Inference" (TESE/DISSERTAÇÃO)
 Aprovado com Distinção
2009/01/28
Concluído
 Master in General Biochemistry (Master)
Universidad de Ciencias Médicas de Villa Clara, Cuba
"Application of the MARCH-INSIDE methodolgy to search more efficient cellulase complexes " (TESE/DISSERTAÇÃO)
 excellente (5 in 5) or 20 values
1998/07/17
Concluído
 Pharmaceutical Sciences (Bachelor)
Universidad Central Marta Abreu de las Villas, Cuba
"Study of parameters influencing on banano genetic transformation using gene gun" (TESE/DISSERTAÇÃO)
 Excellent (4.88 out of 5) or 19.52 in 20
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2018/09/01 - Atual Investigador Auxiliar (carreira) (Investigação) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2019/03/01 - 2019/06/30 Investigador visitante (Investigação) Universitat de València, Espanha
Universitat de València Facultat de Medicina i Odontologia, Espanha
2014/04 - 2018/08 Pós-doutorado (Investigação) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2018/05 - 2018/07 Investigador visitante (Investigação) Universidad Central Marta Abreu de las Villas - Centro de Bioactivos Químicos, Cuba
2016/05 - 2016/08 Investigador visitante (Investigação) Universidad Técnica Particular de Loja Área Biológica y Biomédica, Equador
2016/01 - 2016/04 Investigador visitante (Investigação) Universidad de Granada Escuela Técnica Superior de Ingenierías Informática y de Telecomunicación, Espanha
2012/06 - 2012/09 Investigador visitante (Investigação) Katholieke Universiteit Leuven Centrum voor Microbiële en Plantengenetica, Bélgica
2008/09 - 2008/12 Investigador visitante (Investigação) Universidad de Santiago de Compostela Departamento de Química Orgánica, Espanha
2008/05 - 2008/07 Investigador visitante (Investigação) Universidade de Vigo, Espanha
2006/09 - 2008/04 Assistente de Investigação (carreira) (Investigação) Universidad Central Marta Abreu de las Villas - Centro de Bioactivos Químicos, Cuba
2006/03 - 2006/06 Investigador visitante (Investigação) Università degli Studi di Cagliari Dipartimento Farmaco Chimico Tecnologico, Itália
2002 - 2006 Assistente de Investigação (carreira) (Investigação) Universidad Central Marta Abreu de las Villas - CAP/Facultad de Química y Farmacia, Cuba
2000 - 2002 Estagiário de Investigação (Investigação) Universidad Central Marta Abreu de las Villas - Instituto de Biotecnología de las Plantas, Cuba
1998 - 2000 Estagiário de Investigação (Investigação) Centro de Ingenieria Genetica y Biotecnologia, Cuba

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/01 - 2022/03 Visiting Researcher at Universidad Nacional Autónoma de México (Instituto de Química) Fundação para a Ciência e a Tecnologia, Portugal
Universidad Nacional Autónoma de México Instituto de Quimica, México
2013/11 - 2014/03 Research fellow (project) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2009/09 - 2013/11 PhD student Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2008 - 2009 Research fellow (project) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Projetos

Bolsa

Designação Financiadores
2023/02/28 - 2024/05/31 Computer-Aided Search for Next Generation Antibiotics from Cephalopods' Salivary Glands Proteomes.
UIDB_(COB)
Investigador responsável
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental
Em curso
2018/07 - 2021/07 SYMBIOMICS - Omics of marine symbioses: Metabarcoding and metagenomics characterization of host - microbe adaptation and novel biosynthetic gene clusters
PTDC/BIA-BMA/29985/2017
NORTE/01/0145/FEDER/029985
Investigador
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia

European Regional Development Fund
Concluído
2018/07 - 2021/07 SEXOMICS- Sex and the environment: Genomic decoding and the perpetuation of animal life in a changing world
PTDC/CTA-AMB/31774/2017
POCI-01-0145-FEDER/031774/2017
PTDC/CTA-AMB/31774/2017
Co-Investigador Responsável (Co-IR)
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia

European Regional Development Fund
Concluído
2016/06 - 2019/06 Animal sensory diversity: innovative genomic solutions to enhance perception of environmental stimuli
PTDC/AAG-GLO/6887/2014
Investigador
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2014/04/01 - 2018/08 EvoNeering: An Evolution-Based Framework to Engineer the Synthesis of Biologically Active Oligopeptides
SFRH/BPD/92978/2013
Bolseiro de Pós-Doutoramento
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2013/10 - 2014/03 Estudo da modelação das vias de sinalização dos retinóides e das hormonas da tiróide, por disruptores endócrinos, em invertebrados
PTDC/MAR/115199/2009
Bolseiro de Investigação
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2009/09 - 2013/08 Development of an alignment-free tool based on Quantitative Sequence Function Relationship (QSFR) studies to screen genomes and proteomes of microorganisms: Genomic and proteomic analyses of polyketide synthases and nonribosomal peptide synthetases
SFRH/BD/47256/2008
Bolseiro de Doutoramento
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2008/04 - 2008/09 Phenogenetic drift in evolution: insights into the genetic basis of vertebrate developmental genes
PTDC/BIA-BDE/69144/2006
Bolseiro de Investigação
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2006 - 2008 Searching for efficient cellulase complexes to improve ethanol production from lignocellulosic wastes
CYTED IV.21
Bolseiro de Investigação
Universidad Central Marta Abreu de las Villas - CAP/Facultad de Química y Farmacia, Cuba
 Ciencia y Tecnología para el Desarrollo

Ministerio de Educacion Superior Republica Cuba
Concluído
2000 - 2002 Lengthening of post-harvest life of tropical fruits through the manipulation of genes involved in ripening process
TCP/PER/6713
Bolseiro de Iniciação Científica
Universidad Central Marta Abreu de las Villas - Instituto de Biotecnología de las Plantas, Cuba
 Food and Agriculture Organization of the United Nations

Ministerio de Ciencia Tecnologia y Medio Ambiente
Concluído

Projeto

Designação Financiadores
2020/09/15 - 2026/09/14 EvoNeering: An Evolution-Motivated Genetic Engineering for the Biosynthesis of Antitumor Peptides derived from Marine Cyanobacteria
CEECIND/00543/2018/CP1574/CT0002
10.54499/CEECIND/00543/2018/CP1574/CT0002
Investigador responsável
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2021/01/01 - 2025/12/31 Centro de Investigação Marinha e Ambiental
10.54499/LA/P/0101/2020
Centro de Ciências do Mar, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
Produções

Publicações

Artigo em conferência
  1. Castillo-Mendieta, Kevin; Marrero-Ponce, Yovani; Agüero-Chapin, Guillermin; Pérez-Cárdenas, Mariela. Autor correspondente: Agüero-Chapin, Guillermin. "In Silico Discovery of Hemolytic Peptides Through a Novel Approach Based on Network Science and Similarity Searching Methods". Trabalho apresentado em 1st International Electronic Conference on Toxics, Basel, 2024.
  2. Agüero-Chapin, G. "Emerging Computational Approaches for Antimicrobial Peptide Discovery". Trabalho apresentado em MOL2NET'22, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 8th ed., Cambridge, 2022.
    Publicado • https://doi.org/10.3390/mol2net-08-13484
  3. Agüero-Chapin, Guillermin; García-Hernández, Enrique; Ruiz-Blanco, Yasser; Ávila-Barrientos, Luis; Hernández-García, Enrique; Antunes, Agostinho. "Engineering protein fragments via evolutionary and protein-protein interaction algorithms: De novo design of peptide inhibitors for FOF1-ATP synthase.". Trabalho apresentado em MOL2NET'22, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 8th ed., 2022.
    Publicado • 10.3390/mol2net-08-13936
  4. Marrero-Ponce, Yovani; Romero, Maylin; Rodríguez, Hortensia; Agüero-Chapin, G; Antunes, Agostinho; Aguilera-Mendoza, Longendri; Martinez-Rios, Felix. "A Novel Network Science and Similarity-Searching-Based Approach for Discovering Potential Tumor-Homing Peptides from Antimicrobials". Trabalho apresentado em MOL2NET'22, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 8th ed., 2022.
    Publicado • 10.3390/mol2net-08-13937
  5. Agüero-Chapin, G. "MOL2NET Highlights on: Graph Theory-Based Sequence Descriptors as Remote Homology Predictors". Trabalho apresentado em MOL2NET 2020, International Conference on Multidisciplinary Sciences, 6th edition, Bilbao, 2020.
    Publicado • 10.3390/mol2net-06-06819
  6. Agüero-Chapin, G; Pérez-Machado, G; Antunes, Agostinho; Vitor Vasconselos. "The RNase III substrate specificity from that the E. coli’s to the Humans’". Trabalho apresentado em MOL2NET 2020, International Conference on Multidisciplinary Sciences, 6th edition: session USEDAT-08: USA-Europe Data Analysis Training Program Workshop, Miami, 2020.
    Publicado • 10.3390/mol2net-06-06887
  7. Agüero-Chapin, G. "SeqDivA: Sequence Diversity Analysis Tool for Detecting the Twilight Zone of Alignment Algorithms". Trabalho apresentado em MOL2NET 2020, International Conference on Multidisciplinary Sciences, 6th edition, Bilbao, 2020.
    Publicado • 10.3390/mol2net-06-06883
  8. Agüero-Chapin, G. "Ensemble K-means for semi-supervised learning in enzymatic activity classification of GH-70 enzymes". Trabalho apresentado em MOL2NET 2020, International Conference on Multidisciplinary Sciences, 6th edition, Valencia, 2020.
    Publicado • 10.3390/mol2net-06-06891
  9. Galpert Cañizares, D; Fernández, A; Herrera, F; Antunes, A; Molina Ruiz, R; Agüero-Chapin, G. "Surveying Alignment-free Features for Ortholog Detection in Related Yeast Proteomes by using Supervised Big Data Classifiers". Trabalho apresentado em MOL2NET 2018, International Conference on Multidisciplinary Sciences, 4th edition, 2018.
    10.3390/mol2net-04-05468
  10. Galpert Cañizares, D; del Río García, S; Herrera, F; Ancede Gallardo, E; Antunes, A; Agüero-Chapin, G. "Pairwise Ortholog Detection in Related Yeast Species by Using Big Data Supervised Classifications". Trabalho apresentado em MOL2NET, International Conference on Multidisciplinary Sciences, 2015.
    Publicado • 10.3390/mol2net-1-e002
  11. Agüero-Chapin, G; Molina Ruiz, R; Antunes, A. "TI2BioP: Topological Indices to BioPolymers". Trabalho apresentado em MOL2NET, International Conference on Multidisciplinary Sciences, 2015.
    Publicado • 10.3390/mol2net-1-f011
  12. Teijeira, M; Pérez González, M; Morales Helguera, A; Agüero-Chapin, G; Perez Machado, G; Terán, C. "A new approach of the substructural analysis toward the design of A (1) adenosine receptor agonists". Trabalho apresentado em Third Join Italian-German Purine Club Meeting, Camerino, 2009.
    Publicado • 10.1007/s11302-009-9170-2
Artigo em revista
  1. Castillo-Mendieta, Kevin; Agüero-Chapin, G; Marquez, Edgar; Perez-Castillo, Yunierkis; Barigye, Stephen J.; Pérez-Cárdenas, Mariela; Peréz-Giménez, Facundo; Marrero-Ponce, Yovani. Autor correspondente: Marrero-Ponce, Yovani. "Multiquery Similarity Searching Models: An Alternative Approach for Predicting Hemolytic Activity from Peptide Sequence". Chemical Research in Toxicology (2024): http://dx.doi.org/10.1021/acs.chemrestox.3c00408.
    10.1021/acs.chemrestox.3c00408
  2. Mora, Jose R.; Marquez, Edgar A.; Pérez-Pérez, Noel; Contreras-Torres, Ernesto; Perez-Castillo, Yunierkis; Agüero-Chapin, G; Martinez-Rios, Felix; Marrero-Ponce, Yovani; Barigye, Stephen J.. "Rethinking the applicability domain analysis in QSAR models". Journal of Computer-Aided Molecular Design 38 1 (2024): http://dx.doi.org/10.1007/s10822-024-00550-8.
    10.1007/s10822-024-00550-8
  3. Mateo S. Andino; José R. Mora; José L. Paz; Edgar A. Márquez; Yunierkis Perez-Castillo; Guillermin Agüero-Chapin. "Elucidating the Racemization Mechanism of Aliphatic and Aromatic Amino Acids by In Silico Tools". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms241511877.
    10.3390/ijms241511877
  4. Guillermin Agüero-Chapin; Agostinho Antunes; Yovani Marrero-Ponce. "A 2022 Update on Computational Approaches to the Discovery and Design of Antimicrobial Peptides". Antibiotics (2023): https://doi.org/10.3390/antibiotics12061011.
    10.3390/antibiotics12061011
  5. Guillermin Agüero-Chapin; Agostinho Antunes; José R. Mora; Noel Pérez; Ernesto Contreras-Torres; José R. Valdes-Martini; Felix Martinez-Rios; Cesar H. Zambrano; Yovani Marrero-Ponce. "Complex Networks Analyses of Antibiofilm Peptides: An Emerging Tool for Next-Generation Antimicrobials’ Discovery". Antibiotics (2023): https://doi.org/10.3390/antibiotics12040747.
    10.3390/antibiotics12040747
  6. Sebastián Ayala-Ruano; Yovani Marrero-Ponce; Longendri Aguilera-Mendoza; Noel Pérez; Guillermin Agüero-Chapin; Agostinho Antunes; Ana Cristina Aguilar. "Network Science and Group Fusion Similarity-Based Searching to Explore the Chemical Space of Antiparasitic Peptides". ACS Omega (2022): https://doi.org/10.1021/acsomega.2c03398.
    10.1021/acsomega.2c03398
  7. Yasser B. Ruiz-Blanco; Guillermin Agüero-Chapin; Sandra Romero-Molina; Agostinho Antunes; Lia-Raluca Olari; Barbara Spellerberg; Jan Münch; Elsa Sanchez-Garcia. "ABP-Finder: A Tool to Identify Antibacterial Peptides and the Gram-Staining Type of Targeted Bacteria". Antibiotics (2022): https://doi.org/10.3390/antibiotics11121708.
    10.3390/antibiotics11121708
  8. Contreras-Torres, Ernesto; Marrero-Ponce, Yovani; Terán, Julio E.; Agüero-Chapin, G; Antunes, Agostinho; García-Jacas, César R.. Autor correspondente: Marrero-Ponce, Yovani. "Fuzzy spherical truncation-based multi-linear protein descriptors: From their definition to application in structural-related predictions". Frontiers in Chemistry 10 (2022): http://dx.doi.org/10.3389/fchem.2022.959143.
    Acesso aberto • Publicado • 10.3389/fchem.2022.959143
  9. Guillermin Agüero-Chapin; Deborah Galpert-Cañizares; Dany Domínguez-Pérez; Yovani Marrero-Ponce; Gisselle Pérez-Machado; Marta Teijeira; Agostinho Antunes. "Emerging Computational Approaches for Antimicrobial Peptide Discovery". Antibiotics 11 7 (2022): 936-936. https://doi.org/10.3390/antibiotics11070936.
    10.3390/antibiotics11070936
  10. Luis Pablo Avila-Barrientos; Luis Fernando Cofas-Vargas; Guillermin Agüero-Chapin; Enrique Hernández-García; Sergio Ruiz-Carmona; Norma A. Valdez-Cruz; Mauricio Trujillo-Roldán; et al. "Computational Design of Inhibitors Targeting the Catalytic ß Subunit of Escherichia coli FOF1-ATP Synthase". Antibiotics 11 5 (2022): 557-557. https://doi.org/10.3390/antibiotics11050557.
    10.3390/antibiotics11050557
  11. Maylin Romero; Yovani Marrero-Ponce; Hortensia Rodríguez; Agüero-Chapin G; Agostinho Antunes; Longendri Aguilera-Mendoza; FELIX MARTINEZ-RIOS. "A Novel Network Science and Similarity-Searching-Based Approach for Discovering Potential Tumor-Homing Peptides from Antimicrobials". Antibiotics (2022): https://www.mdpi.com/2079-6382/11/3/401.
    10.3390/antibiotics11030401
  12. Agüero-Chapin, G. "DISTATIS: A Promising Framework to Integrate Distance Matrices in Molecular Phylogenetics.". Current Topics in Medicinal Chemistry (2021): https://doi.org/10.2174/1568026621666210113164605.
    10.2174/1568026621666210113164605
  13. Agüero-Chapin, G. "Promising Probiotic Food Supplement Based on Combination of Yeast Beta-Glucan, Bioselenium and Lactoferrin for Animal Health". Biomedical Journal of Scientific & Technical Research (2020): https://biomedres.us/fulltexts/BJSTR.MS.ID.005271.php.
    10.26717/BJSTR.2020.32.005271
  14. Daniela Almeida; Dany Domínguez-Pérez; Ana Matos; Guillermin Agüero-Chapin; Yuselis Castaño; Vitor Vasconcelos; Alexandre Campos; Agostinho Antunes. "Data Employed in the Construction of a Composite Protein Database for Proteogenomic Analyses of Cephalopods Salivary Apparatus". Data 5 4 (2020): 110-110. https://doi.org/10.3390/data5040110.
    10.3390/data5040110
  15. Agüero-Chapin, G. "Engineering protein fragments via evolutionary and protein-protein interaction algorithms: De novo design of peptide inhibitors for F O F 1 -ATP synthase". FEBS Letters (2020): http://dx.doi.org/10.1002/1873-3468.13988.
    10.1002/1873-3468.13988
  16. Daniela Almeida; Dany Domínguez-Pérez; Ana Matos; Guillermin Agüero-Chapin; Hugo Osório; Vitor Vasconcelos; Alexandre Campos; Agostinho Antunes. "Putative Antimicrobial Peptides of the Posterior Salivary Glands from the Cephalopod Octopus vulgaris Revealed by Exploring a Composite Protein Database". Antibiotics 9 11 (2020): 757-757. https://doi.org/10.3390/antibiotics9110757.
    10.3390/antibiotics9110757
  17. González Valle, Y; Galpert Cañizares, D.; Molina-Ruiz, Reinaldo; Agüero-Chapin, G. "Integración de rasgos y aprendizaje semi-supervisado para la clasificación funcional de enzimas utilizando K-medias de Spark". Revista Cubana de Ciencias Informáticas 14 4 (2020): 134-161. https://rcci.uci.cu/?journal=rcci&page=article&op=view&path[]=2021&path[]=834.
    Publicado
  18. Ana Matos; Dany Domínguez-Pérez; Daniela Almeida; Guillermin Agüero-Chapin; Alexandre Campos; Hugo Osório; Vitor Vasconcelos; Agostinho Antunes. "Shotgun Proteomics of Ascidians Tunic Gives New Insights on Host–Microbe Interactions by Revealing Diverse Antimicrobial Peptides". Marine Drugs (2020): https://doi.org/10.3390/md18070362.
    10.3390/md18070362
  19. Daniela Sánchez-Soto; Guillermin Agüero-Chapin; Vinicio Armijos-Jaramillo; Yunierkis Perez-Castillo; Eduardo Tejera; Agostinho Antunes; Aminael Sánchez-Rodríguez. "ShadowCaster: Compositional Methods under the Shadow of Phylogenetic Models to Detect Horizontal Gene Transfers in Prokaryotes". Genes (2020): https://doi.org/10.3390/genes11070756.
    10.3390/genes11070756
  20. Agüero-Chapin; Galpert; Molina-Ruiz; Ancede-Gallardo; Pérez-Machado; de la Riva; Antunes. "Graph Theory-Based Sequence Descriptors as Remote Homology Predictors". Biomolecules 10 1 (2019): 26. http://dx.doi.org/10.3390/biom10010026.
    10.3390/biom10010026
  21. de la Riva, G.A; Mendoza, F.L; Agüero-Chapin, G. "Known Hepatoprotectors Act as Antioxidants and Immune Stimulators in Stressed Mice. Perspectives in Animal Health Care". Current Pharmaceutical Design 25 (2019): http://dx.doi.org/10.2174/1381612825666190116151628.
    10.2174/1381612825666190116151628
  22. Domínguez-Pérez, D; Durban, J; Agüero-Chapin, G; López, J.T; Molina-Ruiz, R; Almeida, D; Calvete, J. J; Vasconcelos, Vítor; Antunes, A. "The Harderian gland transcriptomes of Caraiba andreae, Cubophis cantherigerus and Tretanorhinus variabilis, three colubroid snakes from Cuba". Genomics (2018): http://dx.doi.org/10.1016/j.ygeno.2018.11.026.
    Acesso aberto • Publicado • 10.1016/j.ygeno.2018.11.026
  23. Deborah Galpert; Alberto Fernández; Francisco Herrera; Agostinho Antunes; Reinaldo Molina-Ruiz; Guillermin Agüero-Chapin. "Surveying alignment-free features for Ortholog detection in related yeast proteomes by using supervised big data classifiers". BMC Bioinformatics (2018): https://doi.org/10.1186/s12859-018-2148-8.
    10.1186/s12859-018-2148-8
  24. Ruiz-Blanco, Y.B; Agüero-Chapin, G; García-Hernández, E; Álvarez, O; Antunes, A; Green, J. "Exploring general-purpose protein features for distinguishing enzymes and non-enzymes within the twilight zone". BMC Bioinformatics 18 1 (2017): https://doi.org/10.1186/s12859-017-1758-x.
    10.1186/s12859-017-1758-x
  25. Colli Mull, J. G; de la Riva, G.A; Vargas Samano, C.D; Perez Machado, G; Agüero-Chapin, G. "Plant Growth Promoting Bacteria Isolated From a Mexican Natural Ecosystem Induce Water Stress Resistance in Maize and Sorghum Plants". Journal of Microbial & Biochemical Technology 9 5 (2017): http://dx.doi.org/10.4172/1948-5948.1000367.
    10.4172/1948-5948.1000367
  26. Agüero-Chapin, G. "Métodos grafo-numéricos de relevancia para la bioinformática. Aplicaciones en la biotecnología vegetal y en el descubrimiento de fármacos.". Anales de la Academia de Ciencias de Cuba 69 2 (2017): http://www.revistaccuba.cu/index.php/revacc/article/view/263/0.
    Publicado
  27. Agüero-Chapin, G; Pérez-Machado, G; Colli Mull, J. G; Ancede-Gallardo, E; Antunes, A; de la Riva, G.A. "How the Protein Architecture of RNases III Influences their Substrate Specificity?". Current Pharmaceutical Design 22 33 (2016): 5065-5071. http://dx.doi.org/10.2174/1381612822666160511150416.
    10.2174/1381612822666160511150416
  28. Diaz-Garcia, C; Agüero-Chapin, G; Antunes, A; Vasconcelos, V. "Editorial (Thematic Issue: Biological Toxins and Medicinal Chemistry: Research and Therapeutic Tools)". Current Topics in Medicinal Chemistry 15 7 (2015): 580-580. http://dx.doi.org/10.2174/1568026615666150217110223.
    Publicado • 10.2174/1568026615666150217110223 • Editor
  29. Galpert, D; del Río, S ; Herrera, F; Ancede-Gallardo, E; Antunes, A; Agüero-Chapin, G. "An Effective Big Data Supervised Imbalanced Classification Approach for Ortholog Detection in Related Yeast Species". BioMed Research International 2015 (2015): 1-12. http://dx.doi.org/10.1155/2015/748681.
    Acesso aberto • 10.1155/2015/748681
  30. de la Riva, G.A; Mull-Collí, J; Ramón-Quiroz, R; García-Ramírez, L; Agüero-Chapin, G. "A Bacterial Strain that Affects Lifecycle of Whiteflies (Bemisia tabaci G, Hemiptera: Aleyrodidae) Isolated from the Charco Azul, Xichú, Guanajuato (Mexico)". Journal of Pure and Applied Microbiology 8 2 (2014): 1031-1042.
    Publicado
  31. Agüero-Chapin, G; Molina-Ruiz, R; Maldonado, E; de la Riva, G; Sánchez-Rodríguez, A; Vasconcelos, V; Antunes, A. "Exploring the Adenylation Domain Repertoire of Nonribosomal Peptide Synthetases Using an Ensemble of Sequence-Search Methods". PLoS ONE 8 7 (2013): e65926. http://dx.doi.org/10.1371/journal.pone.0065926.
    10.1371/journal.pone.0065926
  32. Chapin, Guillermin Agüero. "A graphical and numerical approach for functional annotation and phylogenetic inference". Universidade do Porto (Portugal) (2013): https://publons.com/wos-op/publon/17638569/.
  33. Agüero-Chapin, G; Sánchez-Rodríguez, A; Hidalgo-Yanes, P.I.; Pérez-Castillo, Y; Molina-Ruiz, R; Marchal, K; Vasconcelos, V; Antunes, A. "An Alignment-Free Approach for Eukaryotic ITS2 Annotation and Phylogenetic Inference". PLoS ONE 6 10 (2011): e26638. http://dx.doi.org/10.1371/journal.pone.0026638.
    10.1371/journal.pone.0026638
  34. Agüero-Chapin, G; de la Riva, G.A; Molina-Ruiz, R; Sánchez-Rodríguez, A; Pérez-Machado, G; Vasconcelos, Vítor; Antunes, A. "Non-linear models based on simple topological indices to identify RNase III protein members". Journal of Theoretical Biology 273 1 (2011): 167-178. http://dx.doi.org/10.1016/j.jtbi.2010.12.019.
    Publicado • 10.1016/j.jtbi.2010.12.019
  35. Agüero-Chapin, G; Pérez-Machado, G; Molina-Ruiz, R; Pérez-Castillo, Y; Morales-Helguera, A; Vasconcelos, V; Antunes, A. "TI2BioP: Topological Indices to BioPolymers. Its practical use to unravel cryptic bacteriocin-like domains". Amino Acids 40 2 (2010): 431-442. http://dx.doi.org/10.1007/s00726-010-0653-9.
    10.1007/s00726-010-0653-9
  36. González-Díaz, H; Dea-Ayuela, M.A; Pérez-Montoto, L.G; Prado-Prado, F.J; Agüero-Chapin, G; Bolas-Fernández, F; Vazquez-Padrón, R.I; Ubeira, F. "QSAR for RNases and theoretic–experimental study of molecular diversity on peptide mass fingerprints of a new Leishmania infantum protein". Molecular Diversity 14 2 (2009): 349-369. http://dx.doi.org/10.1007/s11030-009-9178-0.
    Publicado • 10.1007/s11030-009-9178-0
  37. Agüero-Chapin, G; Varona-Santos, Javier; de la Riva, G.A; Antunes, A; González-Villa, T; Uriarte, E; González-Díaz, H. "Alignment-Free Prediction of Polygalacturonases with Pseudofolding Topological Indices: Experimental Isolation fromCoffea arabicaand Prediction of a New Sequence". Journal of Proteome Research 8 4 (2009): 2122-2128. http://dx.doi.org/10.1021/pr800867y.
    Publicado • 10.1021/pr800867y
  38. González-Díaz, H; Cabrera-Pérez, M.A; Agüero-Chapín, G; Cruz-Monteagudo, M; Castañeda-Cancio, N; del Río, M.A; Uriarte, E. "Multi-target QSPR assemble of a Complex Network for the distribution of chemicals to biphasic systems and biological tissues". Chemometrics and Intelligent Laboratory Systems 94 2 (2008): 160-165. http://dx.doi.org/10.1016/j.chemolab.2008.07.006.
    Publicado • 10.1016/j.chemolab.2008.07.006
  39. Agüero-Chapín, G; Antunes, A; Ubeira, F.M; Chou, KC; González-Díaz, H. "Comparative Study of Topological Indices of Macro/Supramolecular RNA Complex Networks". Journal of Chemical Information and Modeling 48 11 (2008): 2265-2277. http://dx.doi.org/10.1021/ci8001809.
    10.1021/ci8001809
  40. Agüero-Chapín, G; González-Díaz, H; de la Riva, G.A; Rodríguez, E; Sánchez-Rodríguez, A; Podda, G; Vazquez-Padrón, R.I. "MMM-QSAR Recognition of Ribonucleases without Alignment:¿ Comparison with an HMM Model and Isolation from Schizosaccharomyces pombe, Prediction, and Experimental Assay of a New Sequence". Journal of Chemical Information and Modeling 48 2 (2008): 434-448. http://dx.doi.org/10.1021/ci7003225.
    10.1021/ci7003225
  41. Cruz-Monteagudo, M; González-Díaz, H; Agüero-Chapín, G; Santana, L; Borges, F; Domínguez, E.R; Podda, G; Uriarte, E. "Computational chemistry development of a unified free energy Markov model for the distribution of 1300 chemicals to 38 different environmental or biological systems". Journal of Computational Chemistry 28 11 (2007): 1909-1923. http://dx.doi.org/10.1002/jcc.20730.
    10.1002/jcc.20730
  42. González-Díaz, H; Agüero-Chapin, G; Varona, J; Molina, R; Delogu, G; Santana, L; Uriarte, E; Podda, G. "2D-RNA-coupling numbers: A new computational chemistry approach to link secondary structure topology with biological function". Journal of Computational Chemistry 28 6 (2007): 1049-1056. http://dx.doi.org/10.1002/jcc.20576.
    10.1002/jcc.20576
  43. Agüero-Chapin, G; González-Díaz, H; Molina, R; Varona-Santos, J; Uriarte, E; González-Díaz, Y. "Novel 2D maps and coupling numbers for protein sequences. The first QSAR study of polygalacturonases; isolation and prediction of a novel sequence fromPsidium guajavaL.". FEBS Letters 580 3 (2006): 723-730. http://dx.doi.org/10.1016/j.febslet.2005.12.072.
    10.1016/j.febslet.2005.12.072
  44. Agüero-Chapin, G; Fouad Sarrouh, B; Jover de la Prida, J; González Suarez, E. "Estudio de la hidrólisis del bagazo con ácido sulfúrico concentrado utilizando dos variantes de una sola etapa y una sola etapa modificada para la obtención de etanol y análisis técnico-económico de dicho proceso". Revista Cubana de Química 18 1 (2006): 95. https://www.redalyc.org/pdf/4435/443543688040.pdf.
  45. González-Díaz, H; Agüero-Chapin, G; Cabrera, M.A; Molina, R; Santana, L; Uriarte, E; Delogu, G; Castañedo, N. "Unified Markov thermodynamics based on stochastic forms to classify drugs considering molecular structure, partition system, and biological species:". Bioorganic & Medicinal Chemistry Letters 15 3 (2005): 551-557. http://dx.doi.org/10.1016/j.bmcl.2004.11.059.
    10.1016/j.bmcl.2004.11.059
  46. Fouad Sarrouh, B; Agüero-Chapin, G; Jover de la Prida, J; González Suarez, E. "Estudio de la hidrólisis del bagazo con ácido sulfúrico concentrado para la obtención de etanol". Centro Azúcar 32 2 (2005): 39-42. http://centroazucar.uclv.edu.cu/media/articulos/PDF/2009/4/6.pdf.
  47. Mesa Garriga, L; González Suarez, E; González Cortés, M; Agüero-Chapin, G. "La producción de etanol: alternativas de materias primas". Revista Cubana de Química 17 1 (2005): 129-137. https://www.redalyc.org/pdf/4435/443543685055.pdf.
  48. Vazquez-Padrón, R.I; de la Riva, G.A; Agüero, Guillermin; Silva, Yussun; Pham, Si.M; Soberón, M; Bravo, A; Abdelouahab, A. "Cryptic endotoxic nature of Bacillus thuringiensis Cry1Ab insecticidal crystal protein". FEBS Letters 570 1-3 (2004): 30-36. http://dx.doi.org/10.1016/j.febslet.2004.06.021.
    10.1016/j.febslet.2004.06.021
  49. Agüero-Chapin, G; Jover de la Prida, J; Mesa Garriga, L; González Suarez, E. "Avances en la producción de bioetanol a partir de residuos lignocelulósicos.". Centro Azúcar 31 4 (2004): 28-30. http://centroazucar.uclv.edu.cu/media/articulos/PDF/2009/4/6.pdf.
  50. Mesa Garriga, L; Agüero-Chapin, G; González Suarez, E. "Obtención de coproductos a partir de residuos de tecnologías utilizadas para obtener biocombustibles.". Centro Azúcar 31 3 (2004): 38-40. http://centroazucar.uclv.edu.cu/media/articulos/PDF/2009/4/6.pdf.
  51. Agüero-Chapin, G; Rodríguez, E; Díaz, L; Bacallao, N; Jiménez, Elio. "Aislamiento de un fragmento del ADNc ACC Oxidasa expresado durante la maduración del fruto de Guayaba Enana". Biotecnología Vegetal 3 2 (2003): 187-189. https://revista.ibp.co.cu/index.php/BV/article/view/259/868.
    Publicado
  52. Mas, L; Agüero-Chapin, G; Gil, V; Reyes, M; Gómez Kosky, R; Ocaña, Bárbara; Martínez, S. "Optimización de parámetros en la transformación de embriones somáticos de banano utilizando pistola de genes". Revista Biotecnología Vegetal 1 (2000): 51-54. https://biblat.unam.mx/es/revista/biotecnologia-vegetal/articulo/optimizacion-de-parametros-en-la-transformacion-de-embriones-somaticos-de-banano-utilizando-pistola-de-genes.
Capítulo de livro
  1. Galpert-Cañizares, D; del Río, S ; Herrera, F; Ancede-Gallardo, Evys; Antunes, A; Agüero-Chapin, G. "Big Data Supervised Pairwise Ortholog Detection in Yeasts". In Yeast - Industrial Applications, 42-63. Croácia: InTech, 2017.
    10.5772/intechopen.70479
  2. Agüero-Chapin, G; Molina-Ruiz, R; Pérez-Machado, G; Vasconcelos, Vítor; Rodríguez-Negrin, Z; Antunes, A. "TI2BioP — Topological Indices to BioPolymers. A Graphical– Numerical Approach for Bioinformatics". In Recent Advances in Biopolymers, 254-277. Croácia: InTech, 2016.
    10.5772/61887
  3. Agüero-Chapin, G; Pérez-Machado, G; Sánchez-Rodríguez, A; Santos, M; Antunes, A. "Alignment-Free Methods for the Detection and Specificity Prediction of Adenylation Domains". In Nonribosomal Peptide and Polyketide Biosynthesis, 253-272. Estados Unidos: Springer New York, 2016.
    10.1007/978-1-4939-3375-4_16
  4. González-Díaz, H; Agüero-Chapin, G; Munteanu, C; Prado-Prado, F.J; Chou, KC; Duardo-Sanchez, A; Patlewicz, G; López-Díaz, Antonio. "Alignment-free models in Plant Genomics: Theoretical, Experimental, and Legal issues". In Advances in Genetics Research, editado por Maria A. Osborne. New York, Estados Unidos: Nova Science Publisher, 2011.
    Publicado
Livro
  1. Agüero-Chapin, G. Computational Approaches in Discovery & Design of Antimicrobial Peptides. Basel, Suiça: MDPI. 2023.
    Publicado • 10.3390/books978-3-0365-7960-3 • Editor
  2. González-Díaz, H; Agüero-Chapin, G; Munteanu, C; Prado-Prado, F.J; Chou, Kuo-Chen; Patlewicz, G; López-Díaz, A. Alignment-free models in plant genomics: Theoretical, experimental, and legal issues. New York, Estados Unidos: Nova Science Publisher. 2010.
    Publicado
Poster em conferência
  1. Agüero-Chapin, G. "ProtDCal aplicación 3: Desarrollo de modelos de identificación de enzimas mediante nuevos descriptores 3D de proteínas.". Trabalho apresentado em VI International Symposium of Chemistry, Villa Clara. Cuba, 2016.
Pré-impressão
  1. Guillermin Agüero-Chapin; Agostinho Antunes; José R. Mora; Noel Pérez; Ernesto Contreras-Torres; José R. Valdes-Martini; Felix Martinez-Rios; Cesar H. Zambrano; Yovani Marrero-Ponce. "Complex Networks Analyses of Antibiofilm Peptides: An Emerging Tool for Next Generation Antimicrobials Discovery". 2023. https://doi.org/10.20944/preprints202303.0193.v1.
    10.20944/preprints202303.0193.v1
  2. Kevin Castillo-Mendieta; Guillermin Agüero-Chapin; Nelson Santiago Vispo; Edgar A. Márquez; Yunierkis Perez-Castillo; Stephen J. Barigye; Yovani Marrero-Ponce. "Peptide Hemolytic Activity Analysis using Visual Data Mining of Similarity-based Complex Networks". 2023. https://doi.org/10.20944/preprints202303.0322.v1.
    10.20944/preprints202303.0322.v1
  3. Castillo-Mendieta, Kevin; Agüero-Chapin, G; Marquez, Edgar A.; Perez-Castillo, Yunierkis; Barigye, Stephen J.; Pérez-Cárdenas, Mariela; Peréz-Giménez, Facundo; Marrero-Ponce, Yovani. Autor correspondente: Marrero-Ponce, Yovani. "A New Robust Method for Predicting Hemolytic Toxicity from Peptide Se-quence". 2023. http://dx.doi.org/10.26434/chemrxiv-2023-1zqzf.
    10.26434/chemrxiv-2023-1zqzf
  4. Guillermin Agüero-Chapin; Dany Domínguez-Pérez; Yovani Marrero-Ponce; Kevin Castillo-Mendieta; Agostinho Antunes. "Unveiling Encrypted Antimicrobial Peptides from Cephalopods' Salivary Glands: A Proteolysis-Driven Virtual Approach". 2023. https://doi.org/10.26434/chemrxiv-2023-rqqqb.
    10.26434/chemrxiv-2023-rqqqb
  5. Ayala-Ruano, Sebastián; Marrero-Ponce, Yovani; Aguilera-Mendoza, Longendri; Pérez, Noel; Agüero-Chapin, Guillermin; Antunes, Agostinho; Aguilar, Ana Cristina. "Exploring the Chemical Space of Antiparasitic Peptides and Discovery of New Promising Leads through a Novel Approach based on Network Science and Similarity Searching". 2022. http://dx.doi.org/10.26434/chemrxiv-2021-tgv69-v2.
    10.26434/chemrxiv-2021-tgv69-v2
  6. Maylin Romero; Yovani Marrero-Ponce; Hortensia Rodríguez; Guillermin Agüero-Chapin; Agostinho Antunes; Longendri Aguilera-Mendoza; Felix Martinez-Rios. "A Novel Network Science and Similarity Searching-Based Approach for Discovering Potential Tumor Homing Peptides from Antimicrobials". 2022. https://doi.org/10.20944/preprints202202.0046.v1.
    10.20944/preprints202202.0046.v1
Tese / Dissertação
  1. Chapin, Guillermin. "A Graphical and Numerical Approach for Functional Annotation and Phylogenetic Inference". Doutoramento, Universidade do Porto Faculdade de Ciências, 2013. https://repositorio-aberto.up.pt/bitstream/10216/69300/2/24615.pdf.

Outros

Outra produção
  1. Sequence Diversity Analysis - SeqDivA version 1.0 (software). SeqDivA is a python-based tool with a friendly GUI designed for Linux and Mac OS. It runs alignment algorithms (water, needle, and blast) to compare all-vs.-all protein, DNA, and RNA sequences.. 2019. Ancede-Gallardo, E; Agüero-Chapin, G. https://github.com/eancedeg/SeqDivA.
  2. ShadowCaster: compositional methods under the shadow of phylogenetic models for the detection of horizontal gene transfer events in prokaryotes (Software).. ShadowCaster is a hybrid approach that sequentially combines a parametric method that incorporates two types of compositional features (k-mers and codon usage) under the shadow of an implicit phylogenetic model built on the basis that the number of orthologs shared between two species is a proxy of the phylogenetic distance.. 2019. Agüero-Chapin, G; Sánchez-Rodríguez, A. http://dx.doi.org/10.1101/684704.
    10.1101/684704
  3. Sequencevectorization Phylogenetic Analysis (SVPhylA 2.0) - Software. SVPhylA is a python tool for the calculation of several alignment-free distances for phylogenetics analysis from the most popular alignment-free approaches. Such alignment-free distances are combined into a consensus/compromise matrix by usingalgorithms like DISTATIS based on Multidimensional Scaling (MSD), LinealPrincipal Component Analysis (PCA) and PCA-Kernel (non-lineal).. 2019. Molina-Ruiz, Reinaldo; Agüero-Chapin, G; Sánchez-Rodríguez, A. https://sourceforge.net/projects/svphyla/.
  4. BigD_ProtDescriptors 2.0 (Big Data for Protein Descriptors Calculations) - Software. This sofware is written on the Big Data PySpark platform for the massive calculation of alignment-free protein descriptors and pairwise similarity/distance metrics.. 2019. Molina-Ruiz, Reinaldo; Galpert Cañizares, D; Agüero-Chapin, G. Not public available until publication.
  5. Software: TI2BioP (Topological indices tobiopolymers) version 3.0 (latest). TI2BioP software allows mainly the calculation oftopological indices (spectral moments) derived from inferred and artificial 2Dstructures of DNA, RNA and proteins being possible to carry out a structure-function correlation irrespective of sequence alignments. TI2BioP version 3.0 is a python platform with a graphical interface designed for Linux OS. https://sourceforge.net/projects/ti2biop/.. 2019. Molina-Ruiz, Reinaldo; Agüero-Chapin, G. https://sourceforge.net/projects/ti2biop/.
  6. Software: Sequence vectorization Phylogenetic Analysis (SVPhylA 2.0). SVPhylA is a python tool for the calculation of several alignment-free distances for phylogenetics analysis from the most popular alignment-free approaches. Such alignment-free distances are combined into a consensus/compromise matrix by using algorithms like DISTATIS based on Multidimensional Scaling (MSD), Lineal Principal Component Analysis (PCA) and PCA-Kernel (non-lineal).. 2019. Molina-Ruiz, Reinaldo; Agüero-Chapin, G. https://sourceforge.net/projects/svphyla/.
  7. Software: BigD_ProtDescriptors 2.0 (Big Data for Protein Descriptors Calculations). This sofware is written on the Big Data PySpark platform for the massive calculation of alignment-free protein descriptors. 2019. Molina-Ruiz, Reinaldo; Agüero-Chapin, G.
  8. TI2BioP (Topological indices to biopolymers) version 2.1 - Software. TI2BioP software allows mainly the calculation of topological indices (spectral moments) derived from inferred and artificial 2D structures of DNA, RNA and proteins being possible to carry out a structure-function correlation irrespective of sequence alignments. TI2BioP version 2.1 is a python platform with a graphical interface designed for Linux OS.. 2017. Molina-Ruiz, R; Agüero-Chapin, G; Pérez González, M. https://sourceforge.net/projects/ti2biop/.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/05/17 Webinar: Integration of Artificial Intelligence-based Tools into Biodiscovery of AMPs with Antibiotic Potential from Cephalopods. Seminars of Advanced Studies on Molecular Design and Bioinformatics.
Universidad San Francisco de Quito (Quito, Equador)
2022/05 Hands-on training sessions for undergraduate students from the University of Porto (Portugal) and the Universidad San Francisco de Quito and Yachay Tech University in Ecuador. Training focused on equipping students with essential skills in utilising bioinformatics tools for sequence analyses. Seminars of Advanced Studies on Molecular Design and Bioinformatics.
(Porto, Portugal)
2019/09 BigDataProtDescriptors, pHCode: High Performance Computer and Spark paradigm in the efficient manipulation of biomolecules. SIGESTIC’ 2019
BioCubaFarma (Varadero, Cuba)
2015/10/27 Evaluación de algoritmos supervisados y no supervisados de detección de genes ortólogos manejando el desbalance de los datos. XIII Congreso Nacional de Reconocimiento de Patrones (RECPAT 2015)
(Santiago de Cuba, Cuba)
2013/06/06 A Computational Chemistry Approach for ITS2 Annotation and Phylogenetic Inference. V International Symposium on Chemistry
Universidad Central de Las Villas - Sociedad Cubana de Química (Santa Clara, Cuba)
2013/03/19 An alignment-free approach for eukaryotic ITS2 annotation and phylogenetic inference International Work-Conference on Bioinformatics and Biomedical Engineering (IWBBIO)
IEEE (Granada, Espanha)
2013/03/14 An alignment-free approach for eukaryotic ITS2 annotation and phylogenetic inference ISCB Africa ASBCB Conference on Bioinformatics (2013)
African Society for Bioinformatics and Computational Biology (Casablanca, Marrocos)
2013/02/20 TI2BioP: Topological Indices to Biopolymers. Its practical use to unravel cryptic bacteriocin-like domains. 2nd BioSyst. EU (2013)
Federation of European Biological Systematic Societies (Vienna, Áustria)
2011/07 Alignment-free Models supported on the TI2BioP methodology to Identify RNase III Protein Members. 8th Seminars of Advanced Studies on Molecular Design and Bioinformatics.
Universidad de La Habana (Havana, Cuba)
2011/05 Péptidos No ribosomales y sus sintetasa: genes y productos 1er Congreso Multidisciplinario de las Ingenierías
(Morelia, México)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2022 - Atual Sea venoms: molecular and ecological innovations of cnidarians and mollusks
Coorientador
 Biologia (Doutoramento)
Universidade do Porto Faculdade de Ciências, Portugal
2021/09 - Atual Protein Structural Classes Identification with AI Combining Alignment-based and Alignment-free Protein Features
Coorientador
 Computational Intelligence (Doutoramento)
Universidad de Granada Departamento de Ciencias de la Computación e Inteligencia Artificial, Espanha
2022/10 - 2023/06 In Silico Discovery of Hemolytic Peptides Through a Novel Approach Based on Network Science and Similarity Searching Methods.
Orientador
 Bachelor in Biology Sciences (Licenciatura/Bacharelato)
Yachay Tech University, Equador
2019/09/01 - 2021/11/09 Functional classification of enzymes using semi-supervised learning and Apache Spark
Coorientador
 Master in Computer Science (Mestrado)
Universidad Central Marta Abreu de las Villas Facultad de Matemática Física y Computación, Cuba
2014/01 - 2016/07 Contribuciones al enfoque de comparación par a par en la detección de genes ortologos.
Coorientador
 Ciencias Técnicas (Doutoramento)
Universidad Central Marta Abreu de las Villas, Cuba
2011/09 - 2012/07 Caracterización de secuencias de ADN y proteínas a través del cálculo de los momentos espectrales
Orientador de Antonio Bouza Pérez
 Licenciatura en Ciencia de la Computación (Licenciatura/Bacharelato)
Universidad Central Marta Abreu de las Villas, Cuba
2009/09 - 2010/07 Desarrollo y Aplicación de la metodología TI2BioP a la identificación de proteínas tipo bacteriocinas
Orientador de Maylín Rodríguez Pérez
 General Biochemistry (Mestrado)
Instituto Superior de Ciencias Médicas de Villa Clara Dr Serafín Ruíz Facultad de Estomatologia de Villa Clara, Cuba
2004/10 - 2005/07 Estudio de alternativas para la obtención de bioetanol a partir de bagazo de caña.
Coorientador de Naudys Garcia Navarro
 Ingeniería Química (Licenciatura/Bacharelato)
Universidad Central Marta Abreu de las Villas, Cuba

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2023/01 - 2023/12 Chairperson of the Session BIOMODE.ECO-08: Biotechnology, Molecular Engineering, Natural Products Development, and Ecology Congress, From Forest to Oceans. Paris, France - Ohio, USA, 2023 . MOL2NET 2023 Conference on Molecular, Biomed, Comput. & Network Science and Engineering, 9th ed. (2023/01 - 2023/12)
Conferência (Membro da Comissão Organizadora)
 Multidisciplinary Digital Publishing Institute AG, Suiça

Ikerbasque, Espanha
2022/01 - 2022/12 Chairperson of the Session MODECO-07, Molecular Sciences, Development, Environmental Sustainability, and Economy Congress, From Amazon to Oceans, Paris, France, EPA, USA,, 2022 . MOL2NET 2022, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 8th ed. (2022/01 - 2022/12)
Conferência (Membro da Comissão Organizadora)
 Multidisciplinary Digital Publishing Institute AG, Suiça

Ikerbasque, Espanha
2021/01/25 - 2022/01/30 Chairperson of the Session 06 . BIOMEDIT-02; ITCs & Biomol. Biomed. Eng. Works., Lund, Sweden-Chengdu, China-New Orleans, USA, 2021 . MOL2NET 2021, International Conference on Multidisciplinary Sciences, 7th edition. (2021/01/30 - 2022/01/30)
Conferência (Membro da Comissão Organizadora)
 Multidisciplinary Digital Publishing Institute AG, Suiça
2020/01/30 - 2021/01/30 Session Chair in MOL2NET-06, International Conference on Multidisciplinary Sciences, ISSN: 2624-5078, MDPI SciForum, Basel, Switzerland, 2020 - Session 06. MODECO-05: Molec. Diversity, Energy, & Ecosystems, Puyo, Ecuador-Porto, Portugal-Paris, France, EPA, USA, 2020 (2020/01 - 2021/01)
Conferência (Membro da Comissão Organizadora)
 Multidisciplinary Digital Publishing Institute AG, Suiça

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2024/03/20 - 2024/03/22 Poster Presentation "In Silico Discovery of Hemolytic Peptides Through a Novel Approach Based on Network Science and Similarity Searching Methods"
Conferência
 The 1st International Electronic Conference on Toxics
Multidisciplinary Digital Publishing Institute AG, Suiça
2020/09/17 - 2020/09/17 Blue Think Conference (Porto, CIIMAR-2020). Three Ascidians Tunic from a Metaproteomic Perspective. Ana Matos, Dany Domínguez-Pérez, Daniela Almeida, Guillermin Agüero-Chapin, Alexandre Campos, Hugo Osório, Vitor Vasconcelos and Agostinho Antunes
Conferência
 Blue Think Conference - FIRST CIIMAR STUDENTS' MEETING (BTC-2020)
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2018/09/09 - 2018/09/12 From Metabarcoding to Metagenomics: Unraveling the evolutionary genomics of host-microbe interactions and search for potential secondary metabolites (Poster). Authors: Anoop Alex, Guillermin Agüero Chapin, Agostinho Antunes.
Congresso
 31st Congress ESPB -European Society for Comparative Physiology & Biochemistry
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2018/06 - 2018/08/01 Surveying Alignment-free Features for Ortholog Detection in Related Yeast Proteomes by using Supervised Big Data Classifiers (doi: 10.3390/mol2net-04-05468; Conference Paper). Authors: Deborah Galpert Cañizares; Alberto Fernández; Francisco Herrera; Agostinho Antunes; Reinaldo Molina Ruiz; Guillermin Agüero-Chapin.
Conferência
 Proceedings of MOL2NET 2018, International Conference on Multidisciplinary Sciences, 4th edition
Ikerbasque, Espanha

Multidisciplinary Digital Publishing Institute AG, Suiça

Universidad del País Vasco Facultad de Ciencia y Tecnología, Espanha
2016/09/18 - 2016/09/23 Exploring the toxin expression in the Harderian gland’s transcriptome of three Cuban snakes (Colubroidea) (Poster) Authors: Dany Domínguez-Pérez, Jordi Durban, Guillermin Agüero-Chapin, Javier Torres Lopez, Reinaldo Molina Ruiz, Bruno Reis, Juan Calvete, Vítor Vasconcelos and Agostinho Antunes
Congresso
 XII Congress of the Pan American Section of the International Society on Toxinology
International Society on Toxinology, Estados Unidos
2016/06/07 - 2016/06/10 Topological Indices to Biopolymers (TI2BioP) and Sequence Vectorization for Phylogenetic Analysis (SVPhyLA). Graphical-Numerical tools for Sequence Encoding (Poster) Authors: Reinaldo Molina, Evys Ancede, Guillermin Agüero, Gisselle Pérez, Agostinho Antunes
Simpósio
 VI International Symposium of Chemistry (SIQ 2016)
Universidad Central Marta Abreu de las Villas, Cuba

Sociedad Cubana de Química, Cuba
2015/12/05 - 2015/12/15 Pairwise Ortholog Detection in Related Yeast Species by Using Big Data Supervised Classifications (doi:10.3390/MOL2NET-1-e002; Conference paper). Authors: Galpert Cañizares, D.; del Río García, S.; Herrera, F.; Ancede Gallardo, E.; Antunes, A.; Agüero-Chapin, G.
Conferência
 Proceedings of MOL2NET 2015, International Conference on Multidisciplinary Sciences
Multidisciplinary Digital Publishing Institute AG, Suiça

Universidad del País Vasco Facultad de Ciencia y Tecnología, Espanha

Ikerbasque, Espanha
2015/12/05 - 2015/12/15 TI2BioP: Topological Indices to BioPolymers (doi:10.3390/MOL2NET-1-F011; Conference paper). Authors: Agüero-Chapin, G.; Molina Ruiz, R.; Antunes, A.
Conferência
 Proceedings of MOL2NET 2015, International Conference on Multidisciplinary Sciences
Ikerbasque, Espanha

Multidisciplinary Digital Publishing Institute AG, Suiça

Universidad del País Vasco Facultad de Ciencia y Tecnología, Espanha
2015/11/25 - 2015/11/27 Esquema de evaluación de algoritmos supervisados y no supervisados de detección de genes ortólogos en levaduras Saccharomycete manejando el desbalance de los datos. Companioni Brito, C.; Galpert Cañizares, D.; Ancede Gallardo, E.; Antunes, A.; Agüero-Chapin, G.
Congresso
 Congreso Internacional de la Sociedad Cubana de Matemática y Computación
Universidad de la Habana, Cuba
2015/06/26 - 2015/06/30 Alignment-free methods for the detection and specificity prediction of Adenylation domains (Poster). Agostinho Antunes, Guillermin Agüero-Chapin, Gisselle Pérez-Machado, Aminael Sánchez-Rodríguez and Miguel Santos.
Encontro
 Evolution 2015
American Society of Naturalists, Estados Unidos

Society of Systematic Biologists, Estados Unidos
2014/12/03 - 2014/12/05 Exploring Adenylation Domains Repertoire Of Nonribosomal Peptide Synthetases Using Four-Color Maps (Poster Presentation). Authors: Guillermin Aguero, Reinaldo Molina, Gisselle Perez, Agostinho Antunes
Conferência
 21 Conferencia de Química
Universidad de Oriente, Cuba

Sociedad Cubana de Química, Cuba
2011/06/12 - 2011/06/15 Alignment-free Models based on the TI2BioP methodology to identify Rnase III protein members (Poster). Guillermin Agüero-Chapin, Gustavo A de la Riva, Reinaldo Molina-Ruiz, Aminael Sánchez-Rodríguez, Gisselle Pérez-Machado, Vítor Vasconcelos and Agostinho Antunes
Encontro
 2nd Iberic Meeting on Medicinal Chemistry
Universidade do Porto, Portugal
2010/10/13 - 2010/10/15 Comparative enzymatic activity of three recombinant RNAse III and effect of bacterial RNAse III expressed in transformed yeasts (Poster). Authors: de la Riva G.A, Agüero–Chapin G, Morales-Aragón JC, Pérez-Machado G, Vasconcelos V and Antunes A
Congresso
 3er Congreso Internacional de Investigación CIPITECH
Instituto Tecnológico de Parral, México
2010/09/19 - 2010/09/24 A general QSAR methodology to predict telomerase inhibition by G-quadruplex stabilization (Poster). Authors: Castillo-González Daimel, Perez-Machado Gisselle, Agüero-Chapin Guillermin, Morales-Helguera Aliuska, Teijeira-Bautista Marta, Cabrera-Perez Miguel Angel
Simpósio
 18th European Symp osium on Quantitative Structure–Activity Relationships -EuroQSAR (2010) “Discovery Informatics & Drug Design” (Rhodes, Greece)
European Federation for Medicinal Chemistry, Itália
2010/06/01 - 2010/06/04 A QSFR-like model to detect proteinaceous bacteriocins. Its practical application to the discovery of new bacteriocin-like domains (Poster). Authors: Guillermin Agüero-Chapin, Gisselle Pérez-Machado, Reinaldo Molina-Ruiz, Yunierkis Pérez-Castillo, Aliuska Morales-Helguera, Victor Vasconcelos and Agostinho Antunes
Simpósio
 IV International Symposium on Chemistry
Universidad Central Marta Abreu de las Villas, Cuba

Sociedad Cubana de Química, Cuba
2009/11/09 - 2009/11/13 QSAR study to polymeric sequences embedded in a novel 2D lattice. "Sesión Omica de Plantas." (Poster). Authors: Guillermin Agüero Chapin, Humberto González-Díaz, Gustavo A de La Riva, Gisselle Pérez-Machado, Agostinho Antunes
Congresso
 XIII Congreso Nacional de Bioquímica y Biología Molecular de Plantas
Centro de Investigación y de Estudios Avanzados Unidad Irapuato, México
2009/11/02 - 2009/11/05 Telomerase inhibitors by G-quadruplex stabilization: A QSAR approach (Poster). Authors: Daimel Castillo González, Miguel Ángel Cabrera Pérez, Gisselle Pérez Machado, Guillermin Agüero Chapin, Aliuska Morales Helguera
Congresso
 Biotecnología Habana 2009 "Aplicaciones Médicas de la Biotecnología"
Centro de Ingenieria Genetica y Biotecnologia, Cuba
2009/07/17 - 2009/07/20 A new approach of the sub-structural analysis toward the design of A1 Adenosine Receptors Agonists (Conference paper). Authors: Marta Teijeria Bautista, Maykel Pérez González, Aliuska Morales Helguera, Guillermin Agüero Chapin, Gisselle Pérez Machado, Carmen Terán Moldes.
Encontro
 Third Join Italian-German Purine Club Meeting Purinergic Receptors. "New Frontiers for Novel Therapies"
Università degli Studi di Camerino, Itália

European Federation for Medicinal Chemistry, Itália
2007/06/05 - 2007/06/08 Computacional design of cellulolytics complexes for improving enzymatic hydrolysis in ethanol production (Poster). Authors: Guillermin Agüero Chapin, Humberto González-Díaz, Gustavo A de La Riva, Agostinho Antunes.
Simpósio
 III Simposio Internacional de Química
Universidad Central Marta Abreu de las Villas, Cuba

Sociedad Cubana de Química, Cuba
2005/12/07 - 2005/12/09 "Study of bagasse hydrolysis using concentrated sulfuric acid for etanol obtaining and technical-economical analysis of this process" (Chemical Engineering Workshop) - "2D RNA-QSAR: assigning ACC oxidase family membership with stochastic molecular descriptors; isolation and prediction of a sequence from Psidium guajava L" (Bioinformatics Workshop)
Conferência
 18 International Conference of Chemistry
Universidad de Oriente Departamento de Química, Cuba

Sociedad Cubana de Química, Cuba
2004/11/18 - 2004/11/22 "Isolation of a ACC Oxidase cDNA fragment expressed during Dwarf Guava’s (Psidium guajava L) fruit ripening" (Poster). Authors: Guillermin Agüero, Edrey Rodríguez, Lisbet Diaz, Neyda Bacallao y Elio Jiménez "Study of bagasse hydrolysis using concentrated sulfuric acid for etanol obtaining and technical-economical analysis of this process" (Poster). Authors: Guillermin Agüero, Boutros Fouad Sarrouh, Josefina Jover
Conferência
 Vl International Conference of Chemistry and Chemical Engineering - II Simposio Internacional de Bioquímica y Biología Molecular
Universidad de la Habana Facultad de Biologia, Cuba
2004/06/14 - 2004/06/18 Study of bagasse hydrolysis using concentrated sulfuric acid for etanol obtaining (Poster). Authors: Boutros Fouad Sarrouh, Guillermin Agüero, Josefina Jover and Erenio González
Conferência
 VIII International Conference on sugar and its derived products “Diversificación 2004”
Asociación de Técnicos Azucareros de Cuba, Cuba
2003/06 - 2003/06 "Advances in bioethanol’s production starting from lignocellulosic material" (Poster). Authors: Guillermin Agüero, Josefina Jover, Erenio Suárez "Alternatives for by-products coming from bio-fuel technology obtaining" (Poster). Authors: Leyanis Mesa, Guillermin Agüero, Erenio Suárez
Conferência
 II Conferencia Internacional de Química
Universidad Central Marta Abreu de las Villas, Cuba

Sociedad Cubana de Química, Cuba
2002/06 - 2002/06 Isolation of a ACC Oxidase cDNA fragment expressed during Dwarf Guava (Psidium guajava L.) fruit ripening (Poster). Authors: Guillermin Agüero, Edrey Rodríguez, Neyda Bacallao and Elio Jiménez
Encontro
 6th Coloquio Internacional de Biotecnología de las Plantas
Universidad Central Marta Abreu de las Villas - Instituto de Biotecnología de las Plantas, Cuba
2001/04/16 - 2001/04/20 Isolation of a ACC Oxidase cDNA fragment expressed during Dwarf Guava ( Psidium guajava L.) fruit ripening (Poster)
Congresso
 Congreso Internacional de Biotecnología de las Plantas, BioVeg 2001
Universidad de Ciego de Avila, Cuba
1999/06/16 - 1999/06/19 "Studies of parameters affecting genetic transformation of banana somatic embryos cv. Gran Enano by gene gun" (Poster) "The inmunopotenciar properties characterization of the Cry 1Ac toxin: possible use of these proteins as adjuvant source in the oral-vaccines preparation" (Poster)
Simpósio
 5to Coloquio Internacional de Biotecnología Vegetal
Universidad Central Marta Abreu de las Villas - Instituto de Biotecnología de las Plantas, Cuba

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2023/05 Identification of epigenetic mechanisms related to immunosuppression phenomena in sepsis and their use as prognostic biomarkers.
Vogal
 REBECA OSCA VERDEGAL (Doutoramento)
Universitat de València Facultat de Medicina i Odontologia, Espanha
2022/11 Deep Learning applications over Heterogeneous Networks: from Multimedia to Genes.
Arguente
 Jesús Fernando Cevallos Moreno (Doutoramento)
Dipartimento di Ingegneria Informatica Automatica e Gestionale, SAPIENZA – Università di Roma, Itália
2022/01/20 Use of circulating histones and their post-translational modifications as biomarkers in sepsis and septic shock.
Vogal
 Jesús Beltrán García (Doutoramento)
Universitat de València Facultat de Medicina i Odontologia, Espanha
2021/11/30 Ecophysiological and transcriptomic response of two intertidal mollusc species to thermal stress
Arguente principal
 Harold Casalís Cantalló (Mestrado)
Universidade de Aveiro, Portugal
2015 Development of reductionist energy models applied to the folding of globular proteins and their generalization into protein descriptors.
Arguente principal
 Yasser Ruiz-Blanco (Doutoramento)
Universidad Central Marta Abreu de las Villas, Cuba

Arbitragem científica em conferência

Nome da conferência Local da conferência
2023/01 - 2023/12 NICE.XSM-09: North-Ibero-America Congress on EXperimental & Simulation Methods, Valencia, Bilbao, Spain - Miami, USA, MOL2NET 2023 University of Valencia, Spain; Miami Dade College, USA; Tulane University, USA.
2022/01 - 2022/12 MOL2NET'22, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 8th ed Multidisciplinary Digital Publication Institute (MDPI)
2020/01/30 - 2021/01/30 Workshop Series on Nanotechnology and Material Sciences (NANOBIOMATJND), Jackson State University (JSU) and North Dakota State University (NDSU), USA MOL2NET 2020, International Conference on Multidisciplinary Sciences, 6th edition
2020/01/30 - 2021/01/30 USEDAT: USA-Europe Data Analysis Training Program Workshop, UPV/EHU, Bilbao, Basque Country-MDC, Miami, USA, 2020 MOL2NET 2020, International Conference on Multidisciplinary Sciences, 6th edition
2020/01/30 - 2021/01/30 USINEWS-04: US-IN-EU Worldwide Science Workshop Series, UMN, Duluth, USA, 2020 MOL2NET 2020, International Conference on Multidisciplinary Sciences, 6th edition
2020/01/30 - 2021/01/30 BIOMEDIT-01; BioMedical & Information Technologies Worldwide Workshop, Chengdu, China, 2020 MOL2NET 2020, International Conference on Multidisciplinary Sciences, 6th edition
2020 - 2021 IWIMSM-04: Iberoamerican Workshop on Model. and Simulation Methods, Valencia, Spain, 2020 MOL2NET 2020, International Conference on Multidisciplinary Sciences, 6th edition

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2020/11 - Atual Antibiotics (Topic Board) (2079-6382) MDPI AG
2020/08 - Atual Marine Drugs (Reviewer Board) (1660-3397) MDPI AG
2021/09/27 - 2023/12 Antibiotics (Guest Editor) ( 2079-6382) MDPI
2022/11/01 - 2023 Frontiers in Bioinformatics (Guest Editor) (2673-7647) Frontiers
2015 - 2015 Current Topics in Medicinal Chemistry (Guest Editor) (1568-0266) Bentham Science

Comissão de avaliação

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2022/08 - Atual Concurso - Bolsas de Iniciação à Investigação (BII) -Verão com Ciência
Avaliador
 Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal Fundação para a Ciência e a Tecnologia
2023/08/10 - 2023/08/24 Jury Member to Assign a Research Grant in the framework of the project ¿AFRICoV - Genomic surveillance of SARS-CoV-2(-like) viruses in African bushmeat markets, and perceptions of health risks related to COVID-19 and bushmeat consumption
Avaliador
 Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal Agence nationale de la recherche
2021/07/19 - 2021/08/17 Concurso - Bolsas de Iniciação à Investigação (BII) -Verão com Ciência
Avaliador
 Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal Fundação para a Ciência e a Tecnologia

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2013 - 2016 Invited Professor in the Master Program Research and Drug Development¿. Subject: Biotechnology Applied to Drug Production. Research and Drug Development (Master) Universidad Central Marta Abreu de las Villas - Centro de Bioactivos Químicos, Cuba
2005 - 2008 Professor of Biochemistry in the Chemical Engineering university course Chemical Engineering (Bachelor) Universidad Central Marta Abreu de las Villas - CAP/Facultad de Química y Farmacia, Cuba
2003 - 2005 Professor of Biochemistry in the Chemistry university course Biochemistry (Bachelor) Universidad Central Marta Abreu de las Villas - CAP/Facultad de Química y Farmacia, Cuba
2002 - 2004 Assistant professor of Microbiology Laboratory in the Chemical Engineering course Chemical Engineering (University degree) (Bachelor) Universidad Central Marta Abreu de las Villas - CAP/Facultad de Química y Farmacia, Cuba

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2011/12/15 Agostinho Antunes e Guillermin Aguero-Chapin, do Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto, desenvolveram com uma equipa de oito cientistas internacionais uma nova metodologia para o estudo de Biopolímeros. Revista Digital Ciencia Hoje (Fonte: https://biologiaesalv12a.blogspot.com/search?q=Guillermin) Ciência Hoje/cienciahoje.pt (https://biologiaesalv12a.blogspot.com/search?q=Guillermin)

Membro de associação

Nome da associação Tipo de participação
2024/01 - Atual PagBiOmicS: Personalised Academic Guidance and Biodiscovery-integrated OMICs Solutions (https://www.pagbiomics.com). Co-Founder
2017 - Atual Ecuatorian Bioinformatics Network Member
2004 - Atual Cuban Chemistry Society Member
2002/09 - Atual Cuban Society of Pharmacology Member

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2014 - 2020 Reviewer of the journals - https://publons.com/researcher/1403725/ (1) Current Bioinformatics (2) Chemical Biology and Drug Design (3) Molecular Biosystem (4) Chemometrics and Intelligent Laboratory Systems (5) Amino Acids (6) BMC Bioinformatics (7) Journal of Proteome Research (8) Computational Biology and Chemistry (9) Current Topics in Medicinal Chemistry (10) Journal of Theoretical Biology (11) Scientific Reports (12) Data (13) Computer Methods and Programs in Biomedicine Springer International Publishing AG, Suiça

Elsevier BV, Países Baixos

Biomed Central Ltd, Reino Unido

American Chemical Society, Estados Unidos

Bentham Science Publishers Ltd, Emiratos Árabes Unidos

John Wiley & Sons Inc, Reino Unido

Royal Society of Chemistry, Reino Unido

Multidisciplinary Digital Publishing Institute AG, Suiça

Springer Nature, Luxemburgo
2019/05 - 2019/05 External Evaluator - Internal Projects of Universidad de Las Américas (Ecuador): Descubrimiento de nuevos estabilizadores del cuarteto-G con actividad antitumoral. Universidad de Las Américas, Equador
2018/11 - 2018/12 External Evaluator of National Projects in Chile: Concurso Nacional de Proyectos FONDECYT (Fondo Nacional de Desarrollo Científico y Tecnológico) Regular 2019. Comisión Nacional de Investigación Científica y Tecnológica, Chile
2018/05/01 - 2018/05/21 External Evaluator - Internal Projects of Universidad de Las Américas (Ecuador) : Desarrollo e implementación computacional de descriptores moleculares y líneas celulares con su posterior aplicación en diversos problemas biológicos Universidad de Las Américas, Equador
2016/06 - 2016/08 External Evaluator of National Projects in Ecuador: “Formación del Grupo de Integración de Datos Quimio-Genómicos del Ecuador” for the Red Nacional de Investigación y Educacion del Ecuador (REDCEDIA): Call Name: Concurso Ecuatoriano de Proyectos en Redes Avanzadas - CEPRA 2016. CEDIA, Equador

Tutoria

Tópico Nome do aluno
2023/11 - 2024/06 Virtual Proteolysis Strategy to Explore the Repertoire of Antimicrobial Peptides from Cnidaria Rita Maria Silva de Sousa
2022/11 - 2023/06 Computer-Aided Search for Next Generation Antibiotics from Cephalopods Salivary Glands Proteomes Júlia Moreira Trancho
Distinções

Prémio

2024 Best Poster Award - The 1st International Electronic Conference on Toxics
Multidisciplinary Digital Publishing Institute AG, Suiça
2018 Annual Regional Award (Coauthor). Combinación de medidas de similitud para la detección escalable de genes ortólogos en especies de levaduras.
Ministerio de Ciencia Tecnologia y Medio Ambiente, Cuba
2015 Annual Award of the Cuban Academy of Sciences (Main Author). "Métodos grafo-numéricos de relevancia para la bioinformática. Aplicaciones en la biotecnología vegetal y en el descubrimiento de fármácos"
Academia de Ciencias de Cuba, Cuba
2013 Annual Regional Award (Main Author) “Development of a graphical and numerical approach for functional annotation and phylogenetic inference in gene/protein families involved in drug discovery”
Ministerio de Ciencia Tecnologia y Medio Ambiente, Cuba
2005 Anual Award of the Cuban Academy of Sciences (Collaborator). "From molecular structure biological activity: Applications and potentialities of novel computational design methods in QSAR, QSPR, QSPkR, QSTR studies, proteomic and bioinformatics"
Academia de Ciencias de Cuba, Cuba
2002 Premio Alvaro Reynoso
Asociación de Técnicos Azucareros de Cuba, Cuba

Outra distinção

2014 Medal of Recognition and Merit for PhD Graduates. Thesis – A Graphical and Numerical Approach for Functional Annotation and Phylogenetic Inference
Universidade do Porto Faculdade de Ciências, Portugal
2006 Top-50 most cited article 2005-2008. "Novel 2D maps and coupling numbers for protein sequences. The first QSAR study of polygalacturonases; isolation and prediction of a novel sequence from Psidium guajava L. FEBS Letters 580 (2006)"
The Federation of European Biochemical Societies, Reino Unido