???global.info.a_carregar???
I am a Research Assistant Professor at NOVA School of Science and Technology (FCT-NOVA), Portugal, and an integrated member of the UCIBIO (Research Unit on Applied Molecular Biosciences). I am also an Honorary Research Fellow at Imperial College London. I obtained my degree in Biochemistry in 2001 from the University of Algarve, Portugal, and completed a Ph.D. degree in Biochemistry in 2007 from ITQB-NOVA. RESEARCH MOTIVATION Glycans are ubiquitous molecules and their structures and functions are highly diverse, representing a largely undiscovered resource for biological applications and novel therapeutic opportunities. Glycan microarrays are now state-of-the-art methods in modern Glycosciences to identify novel glycan-binding proteins and pinpoint glycan function. The focus of my research has been on developing glycome-based microarrays for interrogating glycomes and proteomes leading to: 1) glycan ligand discovery and function; and 2) unraveling of glycan-recognition systems. I am following structure-function integrative approaches combining glycan-microarrays with complementary methodologies such as X-Ray crystallography, NMR and other biophysical techniques. These have been applied to study endogenous and microbial glycan recognition systems, glycan-mediated pathogen-host interactions and antibodies for cancer diagnosis and therapy. OUTPUTS OF SCIENTIFIC ACTIVITY 52 peer-reviewed journal articles, including 7 book chapters, and 13 conference papers (C=1970, WOS h-index 21, as of Feb 2021); 1 patent; CRA with Siamab Therapeutics ; 13 Invited Lectures (international conferences, workshops, schools and seminars); 8 oral communications. FUNDING - 3 FCT individual fellowships/contract (PhD and Post-doc, FCT investigator); 9 FCT research grants (3 PI, 1 co-PI, 5 core CV); Santander Totta 2013 and Bluepharma 2014 Awards; 1 UCIBIO exploratory project; CellMAbs and Siamab funds; total 610K. SUPERVISION Trained and supervised 5 MSc students; 8 PhD students (6 ongoing) and 1 Junior Researcher (DL57/transitional rule contract, ongoing). THE JOURNEY INTO THE GLYCOSCIENCES FIELD I joined the Glycosciences Laboratory of Prof. Ten Feizi (Imperial College London), first as visiting scholar (2004-2005) during my PhD and thereafter as a post-doctoral fellow (2007-2009), funded by the Portuguese FCT. While at the Glycosciences Lab, I developed pioneering work in designer glycan microarray approaches to study glycan recognition systems of biological and biomedical impact and in the setting-up of a state-of-the-art glycan microarray and in its application to glycan-ligand discovery. I returned to Portugal end 2009 and joined the protein crystallography group of Prof. Maria João Romão at FCT-NOVA. Here I implemented the glycan microarray technology combined with X-Ray crystallography to study endogenous lectin recognition systems (e.g. malectin, Dectin-1) and microbial glycan degradation of complex polysaccharides (bacterial cellulosomes). In 2013, I was awarded a 5-year Starting Grant under the highly competitive FCT Investigator international call, which allowed me to start my independent journey and set-up a glycan microarray laboratory, supported by 2 research project grants from Portuguese FCT. This enabled me to train Master and PhD students in Glycosciences, establish key collaborations and attract competitive funds to establish a line of research in Functional Glycobiology at UCIBIO. TEACHING Since 2010, I have been enrolled in teaching Biochemistry and Metabolism at the Biochemistry Section at FCT-NOVA. I am also a scientific advisor and teacher of the e-learning course Glycobiology and Glycochemistry and I started in 2017 the Curricular Unit Glycobiology and Disease, which is given to the Master programs in Biochemistry and Molecular Genetics and Biomedicine.
Identificação

Identificação pessoal

Nome completo
MARIA ANGELINA DE SA PALMA

Nomes de citação

  • Palma, Angelina S.
  • Palma, A.S.

Identificadores de autor

Ciência ID
6719-0FF9-816A
ORCID iD
0000-0001-5797-6555
Google Scholar ID
u0jbW0QAAAAJ
Researcher Id
D-2052-2013
Scopus Author Id
55729139000

Endereços de correio eletrónico

  • angelina.palma@fct.unl.pt (Profissional)

Websites

  • https://www.requimte.pt/ucibio/research-groups/lab/glycolab-functional-glycobiology (Profissional)

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Exatas - Química

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Espanhol; Castelhano Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2)
Formação
Grau Classificação
2009 - 2013
Concluído
Structural biology to study endogenous and microbial recognition systems (Pós-doutoramento)
NOVA University of Lisbon- School of Science and Technology , Portugal
2007 - 2009
Concluído
Novel glycotechnologies to study glycan-protein interactions - Specialization in Glycosciences (Pós-doutoramento)
Imperial College London Glycosciences Laboratory, Reino Unido
2002 - 2007
Concluído
Biochemistry (Doutoramento)
Especialização em Especialidade: Bioquímica
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
"Amyotrophic Lateral Sclerosis: Identification and Characterisation of Biochemical and Molecular Marker" (TESE/DISSERTAÇÃO)
Approved by unanimity
1995 - 2001
Concluído
Biochemistry (Licenciatura)
Universidade do Algarve, Portugal
" "Purification and Enzymatic Characterization of human alpha3/4-Fucosyltransferase III (EC 2.4.1.65)"" (TESE/DISSERTAÇÃO)
19/20
Percurso profissional

Ciência

2019 - Atual Investigador visitante (Investigação)
Empregador
Imperial College London Glycosciences Laboratory, Reino Unido
2018 - Atual Investigador Auxiliar (carreira) (Investigação)
Instituição de acolhimento Empregador
Applied Molecular Biosciences Unit (UCIBIO), Portugal Applied Molecular Biosciences Unit (UCIBIO), Portugal
2013 - 2018 Investigador Auxiliar (carreira) (Investigação)
Instituição de acolhimento Empregador
NOVA University of Lisbon- School of Science and Technology , Portugal NOVA University of Lisbon- School of Science and Technology , Portugal
2009 - 2013 Pós-doutorado (Investigação)
Empregador
NOVA University of Lisbon- School of Science and Technology , Portugal
2007 - 2009 Pós-doutorado (Investigação)
Empregador
Imperial College London Glycosciences Laboratory, Reino Unido
2000 - 2002 Estagiário de Investigação (Investigação)
Empregador
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Docência no Ensino Superior

2016 - 2017 Professor Auxiliar Convidado (Docente Universitário)
Instituição de acolhimento Empregador
NOVA University of Lisbon- School of Science and Technology , Portugal NOVA University of Lisbon- School of Science and Technology , Portugal

Cargos e Funções

2019 - Atual Member of the Executive Committee of the Portuguese Carbohydrate Research Group
Empregador
Portuguese Chemical Society (SPQ), Portugal
2016 - Atual Member of the Commission for the Management of Equipment and other Resources
Instituição de acolhimento Empregador
Applied Molecular Biosciences Unit (UCIBIO), Portugal Applied Molecular Biosciences Unit (UCIBIO), Portugal
2018 - 2020 Member of the Scientific Council of UCIBIO
Empregador
Applied Molecular Biosciences Unit (UCIBIO), Portugal

Outros

2020/01/01 - Atual Group Leader - GlycoLab- Functional Glycobiology Laboratory
Empregador
Applied Molecular Biosciences Unit (UCIBIO), Portugal
Projetos

Bolsa

Designação Financiadores
2020 - Atual GLYCOVID-19 Testing existing glycan-based drugs to neutralize SARS-CoV- 2
140_596817822
Investigador
Applied Molecular Biosciences Unit (UCIBIO), Portugal
Fundação para a Ciência e a Tecnologia, I.P.
2021 - 2024/02/29 Targeting human macrophage galactose C-type lectin towards the development of innovative and alternative cancer therapies
PTDC/QUI-OUT/2586/2020
Associação para a Inovação e Desenvolvimento da FCT, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
2018 - 2021/09 GLYCANTIGENS: Advances in MUC1 Glycan Cancer Antigens: From structure to function in the fight against cancer
PTDC/BIA-MIB/31028/2017
Outra
Fundação para a Ciência e a Tecnologia, I.P. (Lisbon)
2018 - 2021/08 GLYCOINTERACT: Glycan-human microbiome interaction: glycan diversity and recognition in the human gut with impact on health and nutrition
PTDC/BIA-MIB/31730/2017
Investigador responsável
Fundação para a Ciência e a Tecnologia, I.P. (Lisbon)
2018 - 2021 Marine Biotechnology: Prospecting new drugs with antitumor and immunomodulatory activity
FCT/CAPES 2017
Investigador
Fundação para a Ciência e a Tecnologia, I.P. (Lisbon)
2018 - 2021 Yeast4FoodMed: Valuation of brewers spent yeast polysaccharides for food and biomedical applications
PTDC/BAA-AGR/30936/2017
Investigador
Fundação para a Ciência e a Tecnologia, I.P.
2016 - 2019/12 An integrative structural biology approach to characterise the protein-carbohydrate microbial recognition
Provided by PTCRIS: 139494
Investigador
Fundação para a Ciência e a Tecnologia, I.P.
2013 - 2016/12 Development of cohesin- microarrays for determining cohesin-dockerin specificities of novel cellulolytic species
Provided by PTCRIS: 126085
Investigador
Fundação para a Ciência e a Tecnologia, I.P.
2013 - 2016/06 Modern Structural Biology: Resources for the advancement of in-house X-ray Crystallography
Provided by PTCRIS: 125363
Investigador
Fundação para a Ciência e a Tecnologia, I.P.
2013 - 2014/12 Pylori GlycoArrays: Development of microarrays from Helicobacter pylori cell surface glycome toward immunological and serological studies
Provided by PTCRIS: 127236
Investigador responsável
Fundação para a Ciência e a Tecnologia, I.P.
2011 - 2014/08 A carbohydrate microarray platform for discovery of ligands in polysaccharides recognised by microbial carbohydrate-binding modules.
Provided by PTCRIS: 112537
Investigador responsável
Fundação para a Ciência e a Tecnologia, I.P.

Projeto

Designação Financiadores
2013 - 2018 Elucidation of microbial protein-carbohydrate recognition in plant cell wall biodegradation using carbohydrate microarrays and protein X-ray crystallography
IF/00033/2012
Investigador responsável
NOVA University of Lisbon- School of Science and Technology , Portugal
Fundação para a Ciência e a Tecnologia, I.P. (Lisbon)

Outro

Designação Financiadores
2019 - 2023 COST Action CA18103- Innovation with Glycans: new frontiers from synthesis to new biological targets
CA18103
Outra
European Cooperation in Science and Technology
2018 - 2018 Targeting glycan specificity of tumor-specific antibodies for development of effective anti-cancer strategies
CRA Siamab
Investigador responsável
Siamab Therapeutics
2016 - 2016 Assessment of natural compounds as novel anti-diabetic drugs
UCIBIO-REQUIMTE
Investigador responsável
Applied Molecular Biosciences Unit (UCIBIO), Portugal
Applied Molecular Biosciences Unit (UCIBIO)
2014 - 2014 Fighting Fungal Pathogens: Molecular recognition of ß-glucans by the immune receptor Dectin-1
DQ/REQUIMTE-CQFB
Investigador responsável
REQUIMTE
Produções

Publicações

Artigo em revista
  1. Li, Chunxia; Palma, Angelina S; Zhang, Pengtao; Zhang, Yibing; Gao, Chao; Silva, Lisete M; Li, Zhen; et al. "Noncovalent microarrays from synthetic amino-terminating glycans: Implications in expanding glycan microarray diversity and platform comparison". Glycobiology (2021): http://dx.doi.org/10.1093/glycob/cwab037.
    10.1093/glycob/cwab037
  2. Lopes, Nuno; Correia, Viviana G.; Palma, Angelina S.; Brito, Catarina. "Cracking the Breast Cancer Glyco-Code through Glycan-Lectin Interactions: Targeting Immunosuppressive Macrophages". International Journal of Molecular Sciences 22 4 (2021): 1972. http://dx.doi.org/10.3390/ijms22041972.
    10.3390/ijms22041972
  3. Murugesan, G.; Correia, V.G.; Palma, A.S.; Chai, W.; Li, C.; Feizi, T.; Martin, E.; et al. "Siglec-15 recognition of sialoglycans on tumor cell lines can occur independently of sialyl Tn antigen expression". Glycobiology 31 1 (2021): 44-54. http://www.scopus.com/inward/record.url?eid=2-s2.0-85100069840&partnerID=MN8TOARS.
    10.1093/glycob/cwaa048
  4. Silva, L.M.; Correia, V.G.; Moreira, A.S.P.; Domingues, M.R.M.; Ferreira, R.M.; Figueiredo, C.; Azevedo, N.F.; et al. "Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays". Carbohydrate Polymers 253 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85095844367&partnerID=MN8TOARS.
    10.1016/j.carbpol.2020.117350
  5. Vendele, Ingrida; Willment, Janet A.; Silva, Lisete M.; Palma, Angelina S.; Chai, Wengang; Liu, Yan; Feizi, Ten; et al. "Mannan detecting C-type lectin receptor probes recognise immune epitopes with diverse chemical, spatial and phylogenetic heterogeneity in fungal cell walls". PLOS Pathogens 16 1 (2020): e1007927. http://dx.doi.org/10.1371/journal.ppat.1007927.
    10.1371/journal.ppat.1007927
  6. Campanero-Rhodes, M.A.; Palma, A.S.; Menéndez, M.; Solís, D.. "Microarray Strategies for Exploring Bacterial Surface Glycans and Their Interactions With Glycan-Binding Proteins". Frontiers in Microbiology 10 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85078803680&partnerID=MN8TOARS.
    Publicado • 10.3389/fmicb.2019.02909
  7. Brás, N.F.; Neves, R.P.P.; Lopes, F.A.A.; Correia, M.A.S.; Palma, A.S.; Sousa, S.F.; Ramos, M.J.. "Combined in silico and in vitro studies to identify novel antidiabetic flavonoids targeting glycogen phosphorylase". Bioorganic Chemistry (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85098077714&partnerID=MN8TOARS.
    10.1016/j.bioorg.2020.104552
  8. Ribeiro DO; Viegas A; Pires VMR; Medeiros-Silva J; Bule P; Chai W; Marcelo F; et al. "Molecular basis for the preferential recognition of ß1,3-1,4-Glucans by the Family 11 Carbohydrate-Binding Module from Clostridium thermocellum.". The FEBS journal (2019): http://europepmc.org/abstract/med/31794092.
    10.1111/febs.15162
  9. Gao T; Yan J; Liu CC; Palma AS; Guo Z; Xiao M; Chen X; et al. "Chemoenzymatic Synthesis of O-Mannose Glycans Containing Sulfated or Nonsulfated HNK-1 Epitope.". Journal of the American Chemical Society (2019): http://europepmc.org/abstract/med/31738061.
    10.1021/jacs.9b08964
  10. Pandeirada CO; Maricato É; Ferreira SS; Correia VG; Pinheiro BA; Evtuguin DV; Palma AS; et al. "Structural analysis and potential immunostimulatory activity of Nannochloropsis oculata polysaccharides.". Carbohydrate polymers (2019): http://europepmc.org/abstract/med/31320077.
    10.1016/j.carbpol.2019.06.001
  11. Rudkin FM; Raziunaite I; Workman H; Essono S; Belmonte R; MacCallum DM; Johnson EM; et al. "Single human B cell-derived monoclonal anti-Candida antibodies enhance phagocytosis and protect against disseminated candidiasis.". Nature communications (2018): http://europepmc.org/abstract/med/30538246.
    10.1038/s41467-018-07738-1
  12. Li Z; Gao C; Zhang Y; Palma AS; Childs RA; Silva LM; Liu Y; et al. "O-Glycome Beam Search Arrays for Carbohydrate Ligand Discovery.". Molecular & cellular proteomics : MCP (2018): http://europepmc.org/abstract/med/29183914.
    10.1074/mcp.ra117.000285
  13. Loureiro, Liliana R.; Sousa, Diana P.; Ferreira, Dylan; Chai, Wengang; Lima, Luis; Pereira, Carina; Lopes, Carla B.; et al. "Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2-6 sialic acids". Scientific Reports 8 (2018): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000441625500019&KeyUID=WOS:000441625500019.
    10.1038/s41598-018-30421-w
  14. Liu Y; McBride R; Stoll M; Palma AS; Silva L; Agravat S; Aoki-Kinoshita KF; et al. "The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data.". Glycobiology (2016): http://europepmc.org/abstract/med/27993942.
    10.1093/glycob/cww118
  15. Palma, Angelina S.. "Generation and characterization of ß1,2-gluco-oligosaccharide probes from Brucella abortus cyclic ß-glucan and their recognition by C-type lectins of the immune system". Glycobiology (2016): https://www.ncbi.nlm.nih.gov/pubmed/27053576.
    10.1093/glycob/cww041
  16. Palma, Angelina S.; Liu, Yan; Zhang, Hongtao; Zhang, Yibing; McCleary, Barry V.; Yu, Guangli; Huang, Qilin; et al. "Unravelling Glucan Recognition Systems by Glycome Microarrays Using the Designer Approach and Mass Spectrometry". Molecular & Cellular Proteomics 14 4 (2015): 974-988. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000352194400014&KeyUID=WOS:000352194400014.
    10.1074/mcp.M115.048272
  17. Gao, Chao; Liu, Yan; Zhang, Hongtao; Zhang, Yibing; Fukuda, Michiko N.; Palma, Angelina S.; Kozak, Radoslaw P.; et al. "Carbohydrate Sequence of the Prostate Cancer-associated Antigen F77 Assigned by a Mucin O-Glycome Designer Array". Journal of Biological Chemistry 289 23 (2014): 16462-16477.
    10.1074/jbc.M114.558932
  18. Palma, Angelina S.; Feizi, Ten; Childs, Robert A.; Chai, Wengang; Liu, Yan. "The neoglycolipid (NGL)-based oligosaccharide microarray system poised to decipher the meta-glycome". Current Opinion in Chemical Biology 18 (2014): 87-94.
    10.1016/j.cbpa.2014.01.007
  19. Suits, M.D.L.; Pluvinage, B.; Law, A.; Liu, Y.; Palma, A.S.; Chai, W.; Feizi, T.; Boraston, A.B.. "Conformational analysis of the Streptococcus pneumoniae hyaluronate lyase and characterization of its hyaluronanspecific carbohydrate-binding module". Journal of Biological Chemistry 289 39 (2014): 27264-27277. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907587727&partnerID=MN8TOARS.
    10.1074/jbc.M114.578435
  20. Neu, U.; Khan, Z.M.; Schuch, B.; Palma, A.S.; Liu, Y.; Pawlita, M.; Feizi, T.; Stehle, T.. "Structures of B-Lymphotropic Polyomavirus VP1 in Complex with Oligosaccharide Ligands". PLoS Pathogens 9 10 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84887269915&partnerID=MN8TOARS.
    10.1371/journal.ppat.1003714
  21. Crusat, M.; Liu, J.; Palma, A.S.; Childs, R.A.; Liu, Y.; Wharton, S.A.; Lin, Y.P.; et al. "Changes in the hemagglutinin of H5N1 viruses during human infection - Influence on receptor binding". Virology 447 1-2 (2013): 326-337. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886397294&partnerID=MN8TOARS.
    10.1016/j.virol.2013.08.010
  22. Neu, Ursula; Allen, Stacy-Ann A; Blaum, Barbel S; Liu, Yan; Frank, Martin; Palma, Angelina S; Stroh, Luisa J; et al. "A Structure-Guided Mutation in the Major Capsid Protein Retargets BK Polyomavirus.". PLoS pathogens 9 10 (2013): e1003688-e1003688.
    10.1371/journal.ppat.1003688
  23. Graham, L.M.; Gupta, V.; Schafer, G.; Reid, D.M.; Kimberg, M.; Dennehy, K.M.; Hornsell, W.G.; et al. "The C-type lectin receptor CLECSF8 (CLEC4D) is expressed by myeloid cells and triggers cellular activation through syk kinase". Journal of Biological Chemistry 287 31 (2012): 25964-25974. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864389223&partnerID=MN8TOARS.
    10.1074/jbc.M112.384164
  24. Møllegaard, K.M.; Duus, K.; Træholt, S.D.; Thaysen-Andersen, M.; Liu, Y.; Palma, A.S.; Feizi, T.; et al. "The interactions of calreticulin with immunoglobulin G and immunoglobulin y". Biochimica et Biophysica Acta - Proteins and Proteomics 1814 7 (2011): 889-899. http://www.scopus.com/inward/record.url?eid=2-s2.0-79957619270&partnerID=MN8TOARS.
    10.1016/j.bbapap.2011.03.015
  25. Watson, A.A.; Lebedev, A.A.; Hall, B.A.; Fenton-May, A.E.; Vagin, A.A.; Dejnirattisai, W.; Felce, J.; et al. "Structural flexibility of the macrophage dengue virus receptor CLEC5A: Implications for ligand binding and signaling". Journal of Biological Chemistry 286 27 (2011): 24208-24218. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959904816&partnerID=MN8TOARS.
    10.1074/jbc.M111.226142
  26. Feizi, T.; Liu, Y.; Palma, A.S.. "Bacterial, fungal, and algal lectins: Combatants in tug of war against HIV". Structure 19 8 (2011): 1035-1037. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051540436&partnerID=MN8TOARS.
    10.1016/j.str.2011.07.006
  27. Capodicasa, C.; Chiani, P.; Bromuro, C.; De Bernardis, F.; Catellani, M.; Palma, A.S.; Liu, Y.; et al. "Plant production of anti-ß-glucan antibodies for immunotherapy of fungal infections in humans". Plant Biotechnology Journal 9 7 (2011): 776-787. http://www.scopus.com/inward/record.url?eid=2-s2.0-79961172241&partnerID=MN8TOARS.
    10.1111/j.1467-7652.2010.00586.x
  28. Lai, L.; Bumstead, J.; Liu, Y.; Garnett, J.; Campanero-Rhodes, M.A.; Blake, D.P.; Palma, A.S.; et al. "The role of Sialyl glycan recognition in host tissue tropism of the avian parasite Eimeria Tenella". PLoS Pathogens 7 10 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-80055079573&partnerID=MN8TOARS.
    10.1371/journal.ppat.1002296
  29. Palma, A.S.; Liu, Y.; Childs, R.A.; Herbert, C.; Wang, D.; Chai, W.; Feizi, T.. "The human epithelial carcinoma antigen recognized by monoclonal antibody AE3 is expressed on a sulfoglycolipid in addition to neoplastic mucins". Biochemical and Biophysical Research Communications 408 4 (2011): 548-552. http://www.scopus.com/inward/record.url?eid=2-s2.0-79956196885&partnerID=MN8TOARS.
    10.1016/j.bbrc.2011.04.055
  30. Friedrich, N.; Santos, J.M.; Liu, Y.; Palma, A.S.; Leon, E.; Saouros, S.; Kiso, M.; et al. "Members of a novel protein family containing microneme adhesive repeat domains act as sialic acid-binding lectins during host cell invasion by apicomplexan parasites". Journal of Biological Chemistry 285 3 (2010): 2064-2076. http://www.scopus.com/inward/record.url?eid=2-s2.0-76249095009&partnerID=MN8TOARS.
    10.1074/jbc.M109.060988
  31. Dunlop, D.C.; Bonomelli, C.; Mansab, F.; Vasiljevic, S.; Doores, K.J.; Wormald, M.R.; Palma, A.S.; et al. "Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans". Glycobiology 20 7 (2010): 812-823. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956366187&partnerID=MN8TOARS.
    10.1093/glycob/cwq020
  32. Neu, U.; Maginnis, M.S.; Palma, A.S.; Ströh, L.J.; Nelson, C.D.S.; Feizi, T.; Atwood, W.J.; Stehle, T.. "Structure-function analysis of the human JC polyomavirus establishes the LSTc pentasaccharide as a functional receptor motif". Cell Host and Microbe 8 4 (2010): 309-319. http://www.scopus.com/inward/record.url?eid=2-s2.0-77958084582&partnerID=MN8TOARS.
    10.1016/j.chom.2010.09.004
  33. Liu, Y.; Childs, R.A.; Matrosovich, T.; Wharton, S.; Palma, A.S.; Chai, W.; Daniels, R.; et al. "Altered receptor specificity and cell tropism of D222G hemagglutinin mutants isolated from fatal cases of pandemic A(H1N1) 2009 influenza virus". Journal of Virology 84 22 (2010): 12069-12074. http://www.scopus.com/inward/record.url?eid=2-s2.0-78049516347&partnerID=MN8TOARS.
    10.1128/JVI.01639-10
  34. Liu, Y.; Palma, A.S.; Feizi, T.. "Carbohydrate microarrays: Key developments in glycobiology". Biological Chemistry 390 7 (2009): 647-656. http://www.scopus.com/inward/record.url?eid=2-s2.0-68149101314&partnerID=MN8TOARS.
    10.1515/BC.2009.071
  35. Childs, R.A.; Palma, A.S.; Wharton, S.; Matrosovich, T.; Liu, Y.; Chai, W.; Campanero-Rhodes, M.A.; et al. "Receptor-binding specificity of pandemic influenza A (H1N1) 2009 virus determined by carbohydrate microarray". Nature Biotechnology 27 9 (2009): 797-799. http://www.scopus.com/inward/record.url?eid=2-s2.0-70249103855&partnerID=MN8TOARS.
    10.1038/nbt0909-797
  36. Torosantucci, A.; Chiani, P.; Bromuro, C.; De Bernardis, F.; Palma, A.S.; Liu, Y.; Minogna, G.; et al. "Protection by anti-ß-glucan antibodies is associated with restricted ß-1,3 glucan binding specificity and inhibition of fungal growth and adherence". PLoS ONE 4 4 (2009): http://www.scopus.com/inward/record.url?eid=2-s2.0-65449157222&partnerID=MN8TOARS.
    10.1371/journal.pone.0005392
  37. Gomes, C.; Palma, A.S.; Almeida, R.; Regalla, M.; McCluskey, L.F.; Trojanowski, J.Q.; Costa, J.. "Establishment of a cell model of ALS disease: Golgi apparatus disruption occurs independently from apoptosis". Biotechnology Letters 30 4 (2008): 603-610. http://www.scopus.com/inward/record.url?eid=2-s2.0-43149109289&partnerID=MN8TOARS.
    10.1007/s10529-007-9595-z
  38. Schallus, T.; Jaeckh, C.; Fehér, K.; Palma, A.S.; Liu, Y.; Simpson, J.C.; Mackeen, M.; et al. "Malectin: A novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation". Molecular Biology of the Cell 19 8 (2008): 3404-3414. http://www.scopus.com/inward/record.url?eid=2-s2.0-54249136020&partnerID=MN8TOARS.
    10.1091/mbc.E08-04-0354
  39. Palma, A.S.; De Carvalho, M.; Grammel, N.; Pinto, S.; Barata, N.; Conradt, H.S.; Costa, J.. "Proteomic analysis of plasma from Portuguese patients with familial amyotrophic lateral sclerosis". Amyotrophic Lateral Sclerosis 9 6 (2008): 339-349. http://www.scopus.com/inward/record.url?eid=2-s2.0-54049158488&partnerID=MN8TOARS.
    10.1080/17482960801934239
  40. Palma, A.S.; Feizi, T.; Zhang, Y.; Stoll, M.S.; Lawson, A.M.; Díaz-Rodríguez, E.; Campanero-Rhodes, M.A.; et al. "Ligands for the ß-glucan receptor, dectin-1, assigned using "designer" microarrays of oligosaccharide probes (neoglycolipids) generated from glucan polysaccharides". Journal of Biological Chemistry 281 9 (2006): 5771-5779. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646843444&partnerID=MN8TOARS.
    10.1074/jbc.M511461200
  41. Palma, A.; De Carvalho, M.; Barata, N.; Evangelista, T.; Chicau, P.; Regalla, M.; Costa, J.. "Biochemical characterization of plasma in amyotrophic lateral sclerosis: Amino acid and protein composition". Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders 6 2 (2005): 104-110. http://www.scopus.com/inward/record.url?eid=2-s2.0-21344455102&partnerID=MN8TOARS.
    10.1080/14660820410021320
  42. Palma, A.S.; Morais, V.A.; Coelho, A.V.; Costa, J.. "Effect of the manganese ion on human a3/4 fucosyltransferase III activity". BioMetals 17 1 (2004): 35-43. http://www.scopus.com/inward/record.url?eid=2-s2.0-0742286872&partnerID=MN8TOARS.
    10.1023/A:1024485718843
  43. V A Morais; Jacinta Serpa; Angelina de Sá Palma; Teresa Costa; L Maranga; Julia Costa. "Expression and characterization of recombinant human alpha-3/4-fucosyltransferase III from Spodoptera frugiperda (Sf9) and Trichoplusia ni (Tn) cells using the baculovirus expression system". Biochemical Journal 353 Pt 3 (2001): 719-25. https://novaresearch.unl.pt/en/publications/cf1789f7-f59a-4ddd-ab57-09e577c41a58.
  44. Sousa, V.L.; Costa, M.T.; Palma, A.S.; Enguita, F.; Costa, J.. "Localization, purification and specificity of the full-length membrane-bound form of human recombinant a1,3/4-fucosyltransferase from BHK-21B cells". Biochemical Journal 357 3 (2001): 803-810. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035425330&partnerID=MN8TOARS.
    10.1042/0264-6021:3570803
  45. Morais, V.A.; Serpa, J.; Palma, A.S.; Costa, T.; Maranga, L.; Costa, J.. "Expression and characterization of recombinant human a-3/4-fucosyltransferase III from Spodoptera frugiperda (Sf9) and Trichoplusia ni (Tn) cells using the baculovirus expression system". Biochemical Journal 353 3 (2001): 719-725. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035252762&partnerID=MN8TOARS.
    10.1042/0264-6021:3530719
  46. Palma, A.S.; Vila-Verde, C.; Pires, A.S.; Fevereiro, P.S.; Costa, J.. "A novel plant a4-fucosyltransferase (Vaccinium myrtillus L.) synthesises the Lewisa adhesion determinant". FEBS Letters 499 3 (2001): 235-238. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035933278&partnerID=MN8TOARS.
    10.1016/S0014-5793(01)02568-6
Capítulo de livro
  1. Palma, Angelina S.; Chai, Wengang. "Glycan Microarrays with Semi-synthetic Neoglycoconjugate Probes in Understanding Glycobiology". In Synthetic Glycomes, 421-446. Royal Society of Chemistry, 2019.
    10.1039/9781788016575-00421
  2. Correia, Viviana G.; Pinheiro, Benedita A; Carvalho, Ana Luísa; Palma, Angelina S.. "Resistance to Aminoglycosides Glycomics and the Link to the Human Gut Microbiome". In Antibiotic Drug Resistance. Wiley, 2019.
    Publicado
  3. PALMA, MARIA. "Targeting protein-carbohydrate interactions in plant cell-wall biodegradation: the power of carbohydrate microarrays". 159-176. The Royal Society of Chemistry, 2018.
    10.1039/9781788010641-00159
  4. Liu Y; Palma AS; Feizi T; Chai W. "Insights Into Glucan Polysaccharide Recognition Using Glucooligosaccharide Microarrays With Oxime-Linked Neoglycolipid Probes.". In Methods in enzymology. 2018.
    10.1016/bs.mie.2017.09.001
  5. Liu, Y.; Childs, R.A.; Palma, A.S.; Campanero-Rhodes, M.A.; Stoll, M.S.; Chai, W.; Feizi, T.. "Neoglycolipid-based oligosaccharide microarray system: Preparation of ngls and their noncovalent immobilization on nitrocellulose-coated glass slides for microarray analyses". In Methods in Molecular Biology, 117-136. 2012.
    10.1007/978-1-61779-373-8_8
  6. Palma, Angelina S.; Zhang, Yibing; Childs, Robert A.; Campanero-Rhodes, Maria A.; Liu, Yan; Feizi, Ten; Chai, Wengang. "Neoglycolipid-based "designer" oligosaccharide microarrays to define ß-glucan ligands for dectin-1". In Methods in Molecular Biology, 337-359. 2012.
    10.1007/978-1-61779-373-8_23
  7. Palma, A.S.; Liu, Y.; Muhle-Goll, C.; Butters, T.D.; Zhang, Y.; Childs, R.; Chai, W.; Feizi, T.. "Multifaceted approaches including neoglycolipid oligosaccharide microarrays to ligand discovery for malectin". In Methods in Enzymology, 265-286. 2010.
    10.1016/S0076-6879(10)78013-7
Resumo em conferência
  1. Palma, Angelina S.. "CarbArrayART: Carbohydrate Array Analysis and Reporting Tool New software for glycan array for data processing, storage and presentation". Trabalho apresentado em Annual Meeting of the Society-for-Glycobiology, 2018.
    Publicado
  2. Palma, Angelina S.. "New software for glycan array for data processing, storage and presentation". Trabalho apresentado em Annual Meeting of the Society-for-Glycobiology, 2017.
    Aceite para publicação
  3. Palma, Angelina S.. "Probing the unique molecular mechanisms used by Clostridium thermocellum for Cellulosome function". Trabalho apresentado em EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2017.
  4. Palma, Angelina S.. "An integrative strategy to decipher glycan recognition in the human gut microbiome". Trabalho apresentado em Annual Meeting of the Society-for-Glycobiology, Publisher: OXFORD UNIV PRESS, 2016.
    Publicado
  5. Palma, Angelina S.. "Oligosaccharide Microarrays with Neoglycolipid Probes Prepared from Synthetic Amino-Terminating and Naturally-Derived Amino Acid-Terminating Oligosaccharides". Trabalho apresentado em Annual Meeting of the Society-for-Glycobiology, Publisher: OXFORD UNIV PRESS INC, 2016.
    Publicado
  6. Palma, Angelina S.. "Influence of carrier lipid composition on glycan recognition in NGL-based microarrays". Trabalho apresentado em Annual Meeting of the Society-for-Glycobiology on Glycobiology - Accelerating Impact across the Biomedical Sciences, Publisher: OXFORD UNIV PRESS INC,, 2015.
    Publicado
  7. Palma, Angelina S.. "The Structural Basis of the Recognition of Di-glucosylated N-glycans by the ER Lectin Malectin". Trabalho apresentado em Annual Conference of the Society-for-Glycobiology, 2013.
    Publicado
  8. Angelina de Sá Palma; Yan Liu; Yibing Zhang; Hongtao Zhang; Ana S. Luis; Ana Luísa Carvalho; Harry J. Gilbert; et al. "Designer-oligosaccharide microarrays to decipher ligands in mammalian and prokaryotic glucan-recognition systems". 2012.
  9. Palma, Angelina S.. "Designer-oligosaccharide microarrays to decipher ligands in mammalian and prokaryotic glucan-recognition systems". Trabalho apresentado em oint Meeting of the Society-for-Glycobiology and American Society for Matrix Biology , Publisher: OXFORD UNIV PRESS INC, 2012.
    Publicado
  10. Palma, Angelina S.. "Structural flexibility and ligand-binding characteristics of the macrophage dengue virus receptor CLEC5A". Trabalho apresentado em Annual Congress of the British-Society-for-Immunology, Publisher: WILEY-BLACKWELL, 2012.
    Publicado
  11. Palma, Angelina S.. "Observations on Receptor-Binding by Influenza Viruses using the Neoglycolipid (NGL)-Based Carbohydrate Microarray System". Trabalho apresentado em , Annual Conference of the Society-for-Glycobiology Publisher: OXFORD UNIV PRESS INC, 2011.
    Publicado
  12. Palma, Angelina S.. "Neoglycolipid (NGL)-Based Microarrays Toward Defining the Recognition Sequence for Malectin: An ER-Resident Potential Regulator of N-Glycan Processing". Trabalho apresentado em Annual Conference of the Society-for-Glycobiology, Publisher: OXFORD UNIV PRESS INC, 2010.
    Publicado
  13. Palma, Angelina S.. "The Latest on Malectin - A Lectin of the Endoplasmic Reticulum". Trabalho apresentado em Annual Meeting of the Society-for-Glycobiology, Publisher: OXFORD UNIV PRESS INC, 2009.
    Publicado
  14. Palma, Angelina S.. "Malectin- a Novel Lectin of the Endoplasmic Reticulum and a Candidate New Player in the Early Steps Of Protein N-Glycosylation". Trabalho apresentado em Annual Meeting of the Society-for-Glycobiology, Publisher: OXFORD UNIV PRESS INC, 2008.
    Publicado

Propriedade Intelectual

Patente
  1. Paula Videira; Carlos Novo; Liliana Loureiro; Mylene Carrascal; Jose Alexandre Ferreira; Palma, Angelina S.; Lucio Lara Santos; et al. 2019. "L2A5 antibody or functional fragment thereof against tumour antigens (WO/2019/147152, PCT/PT2019/000001)". Portugal.
    Permitida

Outros

Norma técnica
  1. 2016. MIRAGE Initiative for Glycan Microarray data. I am committed to data sharing of curated glycan microarray with the aim to create glycan microarray data public repositories, compliant with MIRAGE (Minimum Information Required for A Glycomics Experiment) initiative. At present the data is shared through the web site of the carbohydrate microarray facility at Imperial College London (https://glycosciences.med.ic.ac.uk/data.html).. DOI: 10.1093/glycob/cww118.
Outra produção
  1. Palma, Angelina S.. 2021. Glycans as Players in Host-Microbe Interactions: A Structural Perspective" in Frontiers Molecular Biosciences. Topic Editor. https://www.frontiersin.org/research-topics/15570/glycans-as-players-in-host-microbe-interactions-a-structural-perspective.
  2. Diana O. Ribeiro. 2020. Protein-carbohydrate recognition in the biodegradation of plant cell wall: Functional and structural studies using carbohydrate microarrays and X-ray crystallography. PhD student Diana de Oliveira Ribeiro Thesis. http://hdl.handle.net/10362/100951.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2020/10/09 Sialyl ligands other than the a2,6-sialyl-Tn O-glycan identified for human Siglec-15 COST INNOGLY WG1-WG3 Joint Meeting : “Glycosylation in Cancer and Tumour Immunology”
i3S – Instituto de Investigação e Inovação em Saúde da University of Porto
2019 At last, functional glycomics: The promise of glycan arrays for deciphering microbial-host interactions 13th International Meeting of the Portuguese Carbohydrate Group – GLUPOR 13
(Porto, Portugal)
2019 Using glycan microarrays in understanding anticancer immunity INNOGLY 1st SIMPOSIUM
(Santiago de Compostela, Espanha)
2018 Targeting protein-carbohydrate interactions in plant cell-wall biodegradation: the power of carbohydrate microarrays 29th International Carbohydrate Symposium – ICS 2018, Young Invited Lecture
(Lisbon, Portugal)
2018 At last, functional glycomics - the promise of glycan arrays for deciphering microbial-host interactions. 8th LAQV-UCIBIO Conference Cycle
Applied Molecular Biosciences Unit (Lisbon, Portugal)
2018 Assessing Human Microbiota Systems for Glycan recognition in the Gut., Lisboa, Portugal, Oral presentation by Viviana Correia, PhD student under my Supervision Young Researcher Workshop, ICS2018
(Lisbon, Portugal)
2018 Unravelling Family 50 CBMs of Clostridium thermocellum: Structural-functional Characterization of a New LysM Domain - Oral presentation by Diana Ribeiro, PhD student under my Supervision 29th International Carbohydrate Symposium – ICS 2018
(Lisbon, Portugal)
2018 Glycoscience: a journey into sweet molecules of life: these are to Biology what dark matter is to the Universe Public talk in the International AstroCamp 2018 sponsored by Ciência Viva
CEIA (Centro de Educação e Interpretação Ambiental), Paredes de Coura (Portugal)
2016 Unravelling glucan recognition systems by glycome microarrays and mass spectrometry 5th Workshop of MS and Carbohydrates,
University of Aveiro, (Aveiro, Portugal)
2016 An integrative strategy to unravel carbohydrate:protein interactions in the Human Gut Microbiome - Oral presentation by Viviana Correia, PhD student under my Supervision (BEST Poster Award) Summer Course on Glycosciences
(Groningen, Países Baixos)
2015 Glycan microarrays as tools for Glycobiology: current applications and future challenges Glycobiology Summer School
(Braga, Portugal)
2015 Unravelling glucan recognition systems by glucome-derived ‘designer’ oligosaccharide microarrays 11th International Meeting GLUPOR 11
(Viseu, Portugal)
2015 Carbohydrate chips to identify protein binders. , Protein school 6th European Conference of Chemistry (EuChem) in Life Sciences
(Lisbon, Portugal)
2014 Glycan microarrays to decipher roles for glycans, challenging molecules of life. EMBO Workshop Glycobiology and Glycochemistry: Applications to human health and disease
(Lisbon, Portugal)
2014 Deciphering glucan-recognition in immunity to fungal pathogens: the role of designer oligosaccharide microarrays. , Seminar at CERMAV
(Grenoble, França)
2013 Ligand discovery of carbohydrate recognition systems: the role of glycan microarrays Invited seminar of Systems Biology Program
University of Aveiro (Aveiro, Portugal)
2011 Insights into host glycan ‘receptors’ for human viruses: The role of glycan microarrays. , Invited lecture at the II Post-Doc Symposium: Glycobiology and Disease
IPATIMUP (Porto, Portugal)
2011 Glycan microarrays. Invited tutorial lecture at the Workshop entitled Glycans in Cell Communication. What kind of Science is Glycoscience?
NOVA University of Lisbon - Faculty of Medical Sciences (Lisbon, Portugal)
2011 Patterns of carbohydrate recognition by glucan-binding proteins: Observations using neoglycolipid (NGL)-based microarrays 9th Carbohydrate Bioengineering Meeting (CBM9)
(Lisbon, Portugal)
2010 Studies of glucan-recognition systems with ‘designer’ oligosaccharide microarrays ESF- EuroGlycoScience Forum Scientific Meeting
(Lisbon, Portugal)
2008 Malectin - a novel lectin of the endoplasmic reticulum and a candidate new player in the early steps of protein N-glycosylation. Annual Meeting of the Society for Glycobiology
(Texas, Estados Unidos)
2008 Studies of glucan-recognition systems with designer oligosaccharide microarrays.Sweden Plant Polysaccharide Workshop
(Suécia)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2020 - Atual Exploring Klebsiella pneumoniae surface polysaccharides signatures and host-pathogen recognition patterns: towards understanding human and environmental persistence
Coorientador
Microbiology (Doutoramento)
2020 - Atual GLYCO-Interact: defining triple negative breast cancer glycan signatures to target tumour-associated macrophages
Coorientador
Biology (Doutoramento)
2019 - Atual Translating the human-microbiome molecular cross-talk using glycan microarray and structural biology strategies (SFRH/BD/143494/2019)
Orientador de Filipa Trovão
PhD programme in Biochemistry (Doutoramento)
NOVA University of Lisbon- School of Science and Technology , Portugal
2019 - Atual Carbohydrate-recognition in the Human Gut – Are Bacteria friends or foes?
Orientador de André Favinha
Master in Biochemistry (Mestrado)
NOVA University of Lisbon- School of Science and Technology , Portugal
2019 - Atual Designing new proteins for human health by capitalising on the unique glycan binding specificity of Malectin
Coorientador de Liliana Ringler
Master of Biochemistry for Health (Mestrado)
NOVA University of Lisbon- School of Science and Technology , Portugal
2019 - Atual Assessment of Natural Compounds as novel anti-diabetic drugs
Coorientador
Biochemistry (Mestrado)
NOVA University of Lisbon- School of Science and Technology , Portugal
2018 - Atual A library of colorectal cancer immunogenic glycopeptides: a step towards novel theragnostics applications (SFRH/BD/142479/2018)
Coorientador de Janine Soares
PhD programme in Molecular Oncology (Doutoramento)
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2018 - Atual Deciphering human-microbiome glyco-code: an integrative approach to uncover protein-glycan interactions in the gut environment (PD/BD/135517/2018)
Orientador de Raquel Costa
PhD programme in Molecular Biosciences
NOVA University of Lisbon- School of Science and Technology , Portugal
2015 - 2020 Deciphering carbohydrate:protein interactions in the Human Microbiome – A combined high-throughput and structural approach (PD/BD/105727/2014)
Orientador de Viviana Correia
PhD programme in Molecular Biosciences (Doutoramento)
NOVA University of Lisbon- School of Science and Technology , Portugal
2015 - 2020 Protein-carbohydrate recognition in the biodegradation of plant cell wall: Functional and structural studies using carbohydrate microarrays and X-ray crystallography (SFRH/BD/100569/2014)
Orientador de Diana Ribeiro
PhD programme in Biochemistry (Doutoramento)
NOVA University of Lisbon- School of Science and Technology , Portugal
2017 - 2019 Targeting glycans as novel players in tumour microenvironment
Orientador
Master in Biochemistry (Mestrado)
NOVA University of Lisbon- School of Science and Technology , Portugal
2016 - 2017 Intestinal Microbiota and recognition to carbohydrates
Orientador de Catarina Leote
Biochemistry (Licenciatura/Bacharelato)
NOVA University of Lisbon- School of Science and Technology , Portugal
2015 - 2016 Protein-carbohydrate recognition in polysaccharide biodegradation: characterization studies using carbohydrate microarrays and macromolecular crystallography
Orientador de Raquel Costa
Master in Biochemistry
NOVA University of Lisbon- School of Science and Technology , Portugal
2014 - 2015 Carbohydrate Microarrays to study protein modules in polysaccharide biodegradation
Orientador de Susana Oliveira
Biochemistry (Licenciatura/Bacharelato)
NOVA University of Lisbon- School of Science and Technology , Portugal
2010 - 2014 Structural characterization and generation of microarrays of Helicobacter pylori cell surface glycans (SFRH/BD/71455/2010)
Coorientador de Lisete Silva
PhD programme in Biochemistry
University of Aveiro - Department of Chemistry, Portugal
2011 - 2012 Structural characterization of human MAlectin in complex with oligosaccharide ligands
Orientador
Biochemistry (Licenciatura/Bacharelato)
NOVA University of Lisbon- School of Science and Technology , Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2017 - Atual Founder of the Works4U project “Funding Applications and Career Development” for Biosciences researchers Workshop Series /training sessions in soft skills and research career management (11 sessions, >600 participants) (2017)
Oficina (workshop) (Coorganizador)
NOVA University of Lisbon- School of Science and Technology , Portugal
2018 - 2018 UCIBIO Annual Meeting (2018 - 2018)
Encontro (Coorganizador)
Applied Molecular Biosciences Unit (UCIBIO), Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2018 - 2018 Chair of the Young Researcher Workshop at ICS 2018 conference
Conferência
29th International Carbohydrate Symposium – ICS 2018
2014 - 2014 Chair of the Glycomics Session at the EMBO Workshop in Glycobiology and Glycochemistry
Conferência
EMBO Workshop Glycobiology and Glycochemistry: Applications to human health and disease

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2018 Chemical Tools For The Study Of N-Glycosylation In Protozoan Parasites
Arguente principal
Jessica Grace Morgan Bevan (Doutoramento)
Universidade de Lisboa Faculdade de Medicina, Portugal
2018 Novel anti-carbohydrate antibodies and T-cell based technologies: a combined approach to cancer therapy
Arguente principal
Liliana Raquel Rodrigues Loureiro (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 Molecular and biochemical studies of a mycobacterial maltokinase and a unique octanoyltransferase: Towards reconstruction of the pathway for methylglucose lipopolysaccharides biosynthesis
Arguente principal
Ana Branco Maranha Tiago (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016 Elucidating the Role of Glycans in Leucocyte Function
Arguente
Mariana Araújo Alves Martins da Silva (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2015 Thomsen-friedenreich Antigens in Bladder Cancer: Evaluation of Their Prognostic Value
Vogal
Paulo Filipe Severino (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Arbitragem científica em conferência

Nome da conferência Local da conferência
2017 - Atual 12th International Meeting of the Portuguese Carbohydrate Group (Glupor12)
2014 - 2014 EMBO Workshop Glycobiology & Glycochemistry

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2017 - Atual Member of Admission Committee for the first stage selection of candidates for the PhD Program in Molecular Biosciences (MolBioS).
Avaliador
NOVA University of Lisbon - ITQB, Portugal

Consultoria / Parecer

Descrição da atividade Instituição / Organização
2010 - Atual Peer-reviewing in international journals: Glycobiology, Journal of Biological Chemistry, Medicinal Chemistry, Carbohydrate Polymers; Biotechnology

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2017 - Atual Curricular Unit in Glycobiology and Disease Glycobiology and Disease (Mestrado) NOVA University of Lisbon- School of Science and Technology , Portugal
2013 - Atual Glycobiology and Glycochemistry international e-learning course - Lecturer and Scientific Advisor Glycobiology and Glycochemistry (Outros) NOVA University of Lisbon- School of Science and Technology , Portugal
2010 - Atual Chemistry and Glycobiology 2nd cycle Master Programme - Lecturer Glycosciences (Mestrado) University of Lisbon, Portugal
2010 - Atual Cell Therapies and Regenerative Medicine Doctoral Programme - Lecturer (Curso de doutoramento (conclusão de unidades curriculares)) NOVA University of Lisbon - ITQB, Portugal
2016 - 2017 Practical modules of the Curricular Unit of Biochemistry (Licenciatura) NOVA University of Lisbon- School of Science and Technology , Portugal
2011 - 2017 Practical modules of the Curricular Unit of Metabolism and Regulation (Licenciatura) NOVA University of Lisbon- School of Science and Technology , Portugal
2015 - 2015 INSTRUCT ISBio 2015 international course for researchers: Integrative Structural Biology tools for the study of protein-ligand interactions - Instructor of Glyco-Array Module (Outros) NOVA University of Lisbon- School of Science and Technology , Portugal
2014 - 2014 INSTRUCT ISBio 2014 international course for researchers: Integrative Structural Biology tools for the study of protein-ligand interactions - Instructor of Glyco-Array Module (Outros) NOVA University of Lisbon- School of Science and Technology , Portugal

Membro de associação

Nome da associação Tipo de participação
2017 - Atual Portuguese Chemical Society (SPQ) Member
2011 - Atual Member of INSTRUCT network Member
2008 - Atual Member of the Society for Glycobiology Member
1999 - Atual Member of the Portuguese Biochemical Society (SPB) Member

Tutoria

Tópico Nome do aluno
2017 - Atual Glycobiology and Glycan microarrays to study microbial proteins Benedita Pinheiro - Junior researcher, under DL57/transitional rule contract
2019 - 2019 Glycobiology and glycotecnhologies Filipa Trovão (Siamab research Fellow)
2016 - 2018 Training in glycan microarrays Frederico Lourenço (MSC student); Carolina Pandeirada (MSC student); Liliana Loureiro (PhD student)
2016 - 2017 Assignment of carbohydrate ligands for bacterial carbohydrate binding modules Raquel Costa MSc BI research Fellow funded by a FCT Grant
2013 - 2014 Implementation of carbohydrate microarray protocols to study bacterial recognition systems Diana Ribeiro MSc BI research Fellow funded by a FCT Grant
Distinções

Prémio

2014 Bluepharma/University of Coimbra Innovation Award
Bluepharma - University of Coimbra, Portugal
2013 Santander-Totta/NOVA Scientific Merit Prize
Santander/NOVA University of Lisbon, Portugal
2008 Travel Fund Award from the Society of Glycobiology
American Society for Glycobiology, Estados Unidos

Outra distinção

2019 Honorary Research Fellow (Department of Surgery & Cancer)
Imperial College London, Reino Unido
2014 Career Accomplishment Honor
City Hall of Paredes de Coura, Portugal
2013 Scientific Merit Honor by the NOVA University of Lisbon
NOVA University of Lisbon, Portugal