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Mara G. Freire graduated in Chemistry in 2003 by the University of Aveiro, Portugal, receiving the “Best Chemistry Student Award” from Dow Portugal. In 2007 she completed her PhD in Chemical Engineering, branch of Bioengineering, by the University of Aveiro, with trainees at Federal University of Rio de Janeiro, Brazil, and Claude Bernard University, Lyon, France, followed by post-doctoral activities at ITQB2, New University of Lisbon, Portugal. In 2012, Freire was an invited professor at Tiradentes University, Sergipe, Brazil. In 2013, Freire returned as an Assistant Researcher to the University of Aveiro, and from 2014-2025 she was a Coordinating Researcher at CICECO - Aveiro Institute of Materials, Chemistry Department, University of Aveiro, Portugal. Currently, Freire is Full Professor and Deputy Chair of the Scientific Council of the University of Aveiro. She is the Vice-Director of CICECO. Freire is member of the European Academy of Sciences and of the Lisbon Academy of Sciences. In addition to being member of several journal editorial boards, Freire is Subject Chair of the Content Selection Advisory Board (CSAB) from Scopus. Freire published +370 papers in peer reviewed journals, +30 book chapters and two books, and has +23,000 citations and h-index of 82. She coordinated/participated in +30 R&D projects, among which two European Research Council (ERC) grants and 2 PathFinder projects from the European Innovation Council (EIC). She has filled 19 national/international patents (9 already granted; 4 licensed). She is the co-founder of the RYAPURTECH spin-off. In addition to other awards and recognitions, Freire received the ECTP-NETZSCH Young Scientist Award in 2014, was recognized amongst the top 20 “Women in Science” in Portugal in 2016, was recognized as one of the 14 rising stars in the Green Chemistry field by the Green Chemistry journal in 2017, was recognized as one of the 100 women in Chemistry by the Royal Society of Chemistry in 2018, was awarded with the “Vicente de Seabra Medal” in 2018, received the Best Researcher Award from the University of Aveiro in 2021, and received the award “Professor Almiro e Castro” in 2023. Related to technology transfer and business ideas, she received the Born from Knowledge award by Agência Nacional de Inovação in the Health field in 2018, was finalist in the Everis Awards (2019) with the RYAPURTECH business case, was awarded (2021) with the spin-off RYAPURTECH by the Macao Young Entreperneur Incubation Centre (MYECI), and was one of the Women TechEU awardees in 2024. Up to date, Freire has completed the supervision of 25 junior researchers or post-doctoral researchers, and 28 PhD, 72 MSc and 53 BSc students.
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Identificação

Identificação pessoal

Nome completo
Mara Guadalupe Freire Martins

Nomes de citação

  • Mara G. Freire

Identificadores de autor

Ciência ID
6718-1145-692F
ORCID iD
0000-0001-8895-0614
Researcher Id
B-8458-2008
Scopus Author Id
7102299235

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Engenharia Química
  • Ciências da Engenharia e Tecnologias - Biotecnologia Industrial
  • Ciências Médicas e da Saúde - Biotecnologia Médica
  • Ciências Exatas - Química - Química Física
  • Ciências Exatas - Química
  • Ciências da Engenharia e Tecnologias - Biotecnologia Industrial - Tecnologias de BioProcessamento

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Inglês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Francês Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2020/12/23
Concluído
 Biotecnologia (Título de Agregado)
Universidade de Aveiro, Portugal
 Aprovado
2007
Concluído
 Engenharia Química (Doutoramento)
Universidade de Aveiro, Portugal
"Arejamento e Extracção em Reactores Biológicos Multifásicos / Aeration and Extraction in Multiphase Biological Reactors" (TESE/DISSERTAÇÃO)
 Aprovado
2003
Concluído
 Química, Ramo de Química Analítica (Licenciatura)
Universidade de Aveiro, Portugal
"n/a" (TESE/DISSERTAÇÃO)
 16
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2014/02 - 2025/12 Investigador Coordenador (carreira) (Investigação) Universidade de Aveiro, Portugal
Universidade de Aveiro CICECO, Portugal
(...)
2013/06/11 - 2014/01/31 Assistente de Investigação (carreira) (Investigação) Universidade de Aveiro, Portugal
Universidade de Aveiro CICECO, Portugal
(...)
2008/01/01 - 2013/06/10 Pós-doutorado (Investigação) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2003/10/01 - 2007/09/24 Investigador (Investigação) Universidade de Aveiro, Portugal
Universidade de Aveiro CICECO, Portugal
(...)
2005/01/06 - 2005/08/31 Investigador (Investigação) Universidade Federal do Rio de Janeiro, Brasil
2004/02/01 - 2004/05/31 Investigador (Investigação) Universidade Claude Bernard-Lyon, França
2003/01/01 - 2003/06/30 Estagiário de Investigação (Investigação) Universidade Federal do Rio de Janeiro, Brasil

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2026/04 - Atual Professor Catedrático (Docente Universitário) Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2012/08/01 - 2012/09/30 Professor Visitante (Docente Universitário) Universidade de Tiradentes, Brasil

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2025/01 - Atual Vice-Director of CICECO-Aveiro Institute of Materials Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2022/09/01 - Atual Election/Member European Academy of Sciences, Bélgica
2022/09/01 - Atual Director of the MSc degree in Biotechnology Universidade de Aveiro, Portugal
2019/03 - Atual Deputy Chair of the Scientific Council of University of Aveiro Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2015/01 - 2024/12 Coordinator of Group 5 (Biomedical and Biomimetic Materials) of CICECO Universidade de Aveiro CICECO, Portugal
2016/01 - 2021/12/31 Member of the Cooperation and Scientific Dissemination Committee Universidade de Aveiro Departamento de Química, Portugal
Universidade de Aveiro, Portugal
2016/01 - 2021/12/31 UATEC (Technology Transfer Unit of University of Aveiro) Pivot Universidade de Aveiro Departamento de Química, Portugal
2017/01 - 2020/12/31 Member of the Young Scientists Seminar Lisbon Academy of Sciences, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/09/01 - Atual Election/Member Academia das Ciências de Lisboa, Portugal
Projetos

Projeto

Designação Financiadores
2017/04 - 2024/03 Implementation of The Discoveries Centre for Regenerative and Precision Medicine, a new Centre of Excellence in Portugal
grant.739572
Investigador
European Commission
2020/06/01 - 2021/12/31 PureIgY: Towards the use of IgY antibodies as alternative therapeutics
Grant Agreement Nº 899921
Investigador responsável
Universidade de Aveiro, Portugal
 European Research Council
Em curso
2018/08/01 - 2021/07/31 Development of Ionic-Liquid-based Devices for the Removal of Cytostatic Drugs From Urine Excreted by Cancer Patients
IonCytDevice
Investigador responsável
Universidade de Aveiro CICECO, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018 - 2021 NanoPurAsp - Development of Sustainable Nanomaterials for the Purification of Antileukemic Drugs
POCI-01-0145-FEDER-031268
Investigador
Universidade de Aveiro, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018 - 2021 PUREmiRSILs - Ionic Liquid-based supports for pre-miRNAs purification targeting Alzheimer's disease
POCI-01-0145-FEDER-029496
Investigador
Fundação para a Ciência e a Tecnologia
Em curso
2018 - 2021 IL2BioPro - Towards the Improvement of Recombinant Proteins Bioprocessing using Ionic Liquids
POCI-01-0145-FEDER-030840
Investigador
Fundação para a Ciência e a Tecnologia
Em curso
2018 - 2021 PUREmiRSILs - Ionic Liquid-based supports for pre-miRNAs purification targeting Alzheimer's disease
POCI-01-0145-FEDER-029496
 Fundação para a Ciência e a Tecnologia
2018 - 2021 NanoPurAsp - Development of Sustainable Nanomaterials for the Purification of Antileukemic Drugs
POCI-01-0145-FEDER-031268
 Fundação para a Ciência e a Tecnologia
2018 - 2021 IL2BioPro - Towards the Improvement of Recombinant Proteins Bioprocessing using Ionic Liquids
POCI-01-0145-FEDER-030840
 Fundação para a Ciência e a Tecnologia
2017/01 - 2020/12 Multi-Purpose Strategies for Broadband Agro-Forest and Fisheries By-Products Valorization: a Step Forward for a Truly Integrated Biorefinery – MultiBiorefinery
POCI-01-0145-FEDER-016403
Investigador
Ministério da Ciência, Tecnologia e Ensino Superior
Em curso
2016/10 - 2020/09 Smart Green Homes – BOSCH
POCI-01-0247-FEDER-007678
Investigador
Bosch
2014/02 - 2019/01 IgY Technology: A Purification Platform using Ionic-Liquid-Based Aqueous Biphasic Systems
grant.337753
Investigador responsável
European Research Council
2016/01 - 2018/12 Natural Deep Eutectic Solvents: A platform to Boost Eucalyptus globulus and Quercus suber cork integrated Biorefineries
grant.Provided by PTCRIS: 139816
Investigador
Foundation for Science and Technology
2015/10 - 2018/09 Optimization and Scale-up of Novel Ionic-Liquid-based Purification Processes for Recombinant Green Fluorescent Protein produced by Escherichia coli
grant.Provided by PTCRIS: 147652
Investigador
Foundation for Science and Technology
2014/03/01 - 2015/02/28 Development of a sustainable technology for the extraction and purification of chlorophylls from biomass
EXPL/QEQ-PRS/0224/2013
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2014/03 - 2015/02 Development of a sustainable technology for the extraction and purification of chlorophylls from biomass
EXPL/QEQ-PRS/0224/2013
 Fundação para a Ciência e a Tecnologia
2012/01/01 - 2015 Ionic Liquids as Promoters of Aqueous Biphasic Systems: The Role of van der Waals and Coulomb Interactions
PTDC/QUI-QUI/121520/2010
Investigador responsável
Fundação para a Ciência e a Tecnologia
Concluído
2012/01 - 2015 Ionic Liquids as Promoters of Aqueous Biphasic Systems: The Role of van der Waals and Coulomb Interactions
PTDC/QUI-QUI/121520/2010
 Fundação para a Ciência e a Tecnologia
2012 - 2015 Development of New Oxygen Therapeutics using Fluorinated Ionic Liquids
PTDC/EQU-FTT/118800/2010
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2012 - 2015 Development of New Oxygen Therapeutics using Fluorinated Ionic Liquids
PTDC/EQU-FTT/118800/2010
 Fundação para a Ciência e a Tecnologia
2012 - 2014 Extração e Purificação de Biomoléculas
n.a.
Investigador
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Concluído
2010 - 2012 Aplicação de Sistemas Aquosos Bifásicos Constituídos por Líquidos Iónicos no Desenvolvimento de Diagnósticos de Câncer do Sistema Adrenalina
n.a.
Investigador
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Concluído
2009 - 2011 The Best of Two Worlds: Ionic liquids as Active Pharmaceutical Ingredients
PTDC/EQU-EPR/104554/2008
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2009 - 2011 The Best of Two Worlds: Ionic liquids as Active Pharmaceutical Ingredients
PTDC/EQU-EPR/104554/2008
 Fundação para a Ciência e a Tecnologia
2007 - 2009 Anchoring Basic Parameters for Fundamental Predictive Models in Liquid Salt Systems
PTDC/QUI/72903/2006
Investigador
Universidade de Aveiro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2007 - 2009 Anchoring Basic Parameters for Fundamental Predictive Models in Liquid Salt Systems
PTDC/QUI/72903/2006
 Fundação para a Ciência e a Tecnologia
2005 - 2007 Equilibrium and Interfacial Properties of Water + Oil Systems
POCI/EQU/58239/2004
Investigador
Universidade de Aveiro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2005 - 2007 Equilibrium and Interfacial Properties of Water + Oil Systems
POCI/EQU/58239/2004
 Fundação para a Ciência e a Tecnologia
Produções

Publicações

Artigo em conferência
  1. Cátia Venâncio; Bruna Monteiro; Rafael Francisco; Márcia C. Neves; Mara G. Freire; Ana Catarina A. Sousa; Isabel Lopes. "Ecotoxicological Tools to Assess Cytostatic Effects in Freshwater Environments: Aiding Drug Prioritization". 2022.
    10.3390/ECMC2022-13246
  2. Ferreira, A.R.; Freire, M.G.; Crespo, J.G.; Coutinho, J.A.P.. "Prediction of liquid-liquid equilibria of (ionic liquid + hydrocarbon) systems by COSMO-RS". 2010.
  3. Amaral, P.F.F.; Freire, M.G.; Rocha-Leão, M.H.M.; Marrucho, M.; Coelho, M.A.Z.; Coutinho, J.A.P.. "Study of mass transfer performance in a multiphase bioreactor for lipase production by Yarrowia lipolytica". 2006.
Artigo em revista
  1. Matheus M. Pereira; Sónia N. Pedro; Francisca A. e Silva; João A.P. Coutinho; Mara G. Freire. "Unlocking chromatographic quantification of serum lactate dehydrogenase via ionic-liquid-based aqueous biphasic system pretreatment". Journal of Ionic Liquids (2026): https://doi.org/10.1016/j.jil.2026.100197.
    10.1016/j.jil.2026.100197
  2. Maria S.M. Mendes; Inês B. Santana; Mara G. Freire; Francisca A. e Silva. "Controlling serum protein depletion in aqueous biphasic systems: interphase precipitation versus bottom phase retention for bisphenol A monitoring". Analytica Chimica Acta (2026): https://doi.org/10.1016/j.aca.2026.345346.
    10.1016/j.aca.2026.345346
  3. Bojan Kopilovic; Nabila Laroui; João A.P. Coutinho; Chantal Pichon; Mara G. Freire. "Nasal Delivery of mRNA Using Thermoresponsive Gellable Aqueous Biphasic Systems". Small (2026): https://doi.org/10.1002/smll.202409527.
    10.1002/smll.202409527
  4. Dajana Lazarevic; Bojan Kopilovic; Sanja J. Armakovic; Stevan Armakovic; Bruno M. Baptista; Fani Sousa; Mara G. Freire; Slobodan B. Gadžuric; Tatjana Trtic-Petrovic. "Integrated Extraction, Enrichment, and Formulation of Parthenolide Using Thermoreversible Aqueous Biphasic Systems toward Antitumoral Applications". ACS Sustainable Chemistry & Engineering (2026): https://doi.org/10.1021/acssuschemeng.5c10881.
    10.1021/acssuschemeng.5c10881
  5. Maria S.M. Mendes; Virginia Chu; Mara G. Freire; Francisca A. e Silva; João P. Conde. "Ionic-liquid-based aqueous biphasic systems meet microfluidics: from antibodies to aptamers in prostate-specific antigen detection". Analytica Chimica Acta (2026): https://doi.org/10.1016/j.aca.2025.345001.
    10.1016/j.aca.2025.345001
  6. Filipe S. Buarque; Cariny Polesca; Bernardo D. Ribeiro; Maria Alice Z. Coelho; Mara G. Freire. "From textile waste to sustainable biomaterials: the role of ionic liquids and deep eutectic solvents in protein-based textile waste valorization". Green Chemistry (2026): https://doi.org/10.1039/D5GC06719G.
    10.1039/D5GC06719G
  7. Maria S. M. Mendes; Inês Agostinho; Maria C. Souza; Virginia Chu; Mara G. Freire; Francisca A. e Silva; João P. Conde. "Integrated strategy for breast cancer biomarker analysis using dual ionic liquid aqueous biphasic systems and microfluidic immunoassays". Lab on a Chip (2026): https://doi.org/10.1039/D5LC01010A.
    10.1039/D5LC01010A
  8. Maria S. M. Mendes; Sofia Pedro; Mara G. Freire; Francisca A. e Silva. "Adapting aqueous biphasic systems to solid-phase extraction for bioanalytical applications: high-abundance protein depletion and prostate-specific antigen extraction from human serum". Analytical Methods (2026): https://doi.org/10.1039/D5AY02123E.
    10.1039/D5AY02123E
  9. Rita Carapito; José Bento; Mattia Sponchioni; Mara G. Freire; Fani Sousa. "Multimodal chromatography for the selective capture of pre-miRNA-29b therapeutics". Separation and Purification Technology (2025): https://doi.org/10.1016/j.seppur.2025.134887.
    10.1016/j.seppur.2025.134887
  10. Cariny Polesca; Rita Sobreiro-Almeida; Helena Passos; João A. P. Coutinho; Jason P. Hallett; João F. Mano; Mara G. Freire. "Engineered from Waste: Ionic Liquid Processing of Keratin for 3D Printing Biomedical Scaffolds". ACS Materials Letters (2025): https://doi.org/10.1021/acsmaterialslett.5c00629.
    10.1021/acsmaterialslett.5c00629
  11. Bojan Kopilovic; Nabila Laroui; Mathieu Berchel; Paul-Alain Jaffrès; Patrick Midoux; Mara G. Freire; Chantal Pichon. "Maltodextrin-modified lipoplexes for enhanced mucosal penetration and efficient mRNA delivery". Materials Today Bio (2025): https://doi.org/10.1016/j.mtbio.2025.101975.
    10.1016/j.mtbio.2025.101975
  12. Raquel O. Cristóvão; Rita A.M. Barros; Teresa P. Marramaque; Gonçalo G. Aguiar; Mafalda R. Almeida; Sónia A.C. Carabineiro; Gabriela B. de Paiva; et al. "One-step purification of L-asparaginase from cell extracts using carbon xerogels". Separation and Purification Technology (2025): https://doi.org/10.1016/j.seppur.2024.128969.
    10.1016/j.seppur.2024.128969
  13. Ana F. C. S. Rufino; Emanuel V. Capela; Maria V. Quental; João A. P. Coutinho; Milan B. Vraneš; Slobodan B. Gadžuric; Francisca A. e Silva; Mara G. Freire. "Widening the Stimuli-Responsiveness of Aqueous Biphasic Systems by Changing the Ionic Liquid Cation Basicity". Chemistry – A European Journal (2025): https://doi.org/10.1002/chem.202403605.
    10.1002/chem.202403605
  14. Cariny Polesca; Helena Passos; Ana C. A. Sousa; Nguyen Minh Tue; João A. P. Coutinho; Tatsuya Kunisue; Mara G. Freire. "Sustainable pretreatment of blood samples using hydrophobic eutectic solvents to improve the detection of bisphenol A". Green Chemistry (2025): https://doi.org/10.1039/D4GC03396E.
    10.1039/D4GC03396E
  15. Rafael Francisco; Bruna Monteiro; Maria J. Santos; Francisca A. e Silva; Catia Venancio; Marcia C. Neves; Isabel Lopes; Ana C.A. Sousa; Mara G. Freire. "Tackling water contamination by oncologic drugs: Supported ionic liquids as sustainable adsorbents for cyclophosphamide removal". Journal of Environmental Management (2024): https://doi.org/10.1016/j.jenvman.2024.122995.
    10.1016/j.jenvman.2024.122995
  16. Joana C. Almeida; Celso E. D. Cardoso; Márcia Neves; Tito Trindade; Mara G. Freire; Eduarda Pereira. "Ionic-Liquid-Supported Magnetic Nanoparticles: Synthesis, Characterization, and Their Use for the Separation of Co and Ni from Li in Aqueous Solutions". European Journal of Inorganic Chemistry (2024): https://doi.org/10.1002/ejic.202400237.
    10.1002/ejic.202400237
  17. Rita A. M. Barros; Raquel O. Cristóvão; Inês. G. Carneiro; Maria A. Barros; Matheus M. Pereira; Sónia A. C. Carabineiro; Mara G. Freire; et al. "Improved L-Asparaginase Properties and Reusability by Immobilization onto Functionalized Carbon Xerogels". ChemPlusChem (2024): https://doi.org/10.1002/cplu.202400025.
    10.1002/cplu.202400025
  18. Cátia F. Monteiro; Maria C. Gomes; Pankaj Bharmoria; Mara G. Freire; João A. P. Coutinho; Catarina A. Custódio; João F. Mano. "Human Platelet Lysate-Derived Nanofibrils as Building Blocks to Produce Free-Standing Membranes for Cell Self-Aggregation". ACS Nano (2024): https://doi.org/10.1021/acsnano.4c02790.
    10.1021/acsnano.4c02790
  19. Marguerita E. Rosa; Maria S.M. Mendes; Diana C.V. Belchior; João A.P. Coutinho; Francisca A. e Silva; Mara G. Freire. "Enhancing biomarker detection in human serum for lung cancer diagnosis: Aqueous biphasic systems for simultaneous depletion of high-abundance proteins and efficient extraction of CYFRA 21–1". Advances in Sample Preparation (2024): https://doi.org/10.1016/j.sampre.2024.100116.
    10.1016/j.sampre.2024.100116
  20. Pankaj Bharmoria; Alesia A. Tietze; Dibyendu Mondal; Tejwant Singh Kang; Arvind Kumar; Mara G Freire. "Do Ionic Liquids Exhibit the Required Characteristics to Dissolve, Extract, Stabilize, and Purify Proteins? Past-Present-Future Assessment". Chemical Reviews (2024): https://doi.org/10.1021/acs.chemrev.3c00551.
    10.1021/acs.chemrev.3c00551
  21. Joana C. Almeida; Márcia C. Neves; Tito Trindade; Mara G. Freire; Eduarda Pereira. "Silica Supported Ionic Liquids for the Efficient and Selective Recovery of Platinum and Palladium from Aqueous Media". ACS Sustainable Chemistry & Engineering (2024): https://doi.org/10.1021/acssuschemeng.3c06263.
    10.1021/acssuschemeng.3c06263
  22. Ana M. Ferreira; Isabela Sales; Sónia A. O. Santos; Tiago Santos; Fátima Nogueira; Silvana Mattedi; Simão P. Pinho; João A. P. Coutinho; Mara G. Freire. "Enhanced Antimalarial Activity of Extracts of Artemisia annua L. Achieved with Aqueous Solutions of Salicylate Salts and Ionic Liquids". Chem & Bio Engineering (2024): https://doi.org/10.1021/cbe.3c00005.
    10.1021/cbe.3c00005
  23. Cariny Polesca; Helena Passos; Pedro Y. S. Nakasu; João A. P. Coutinho; Mara G. Freire; Jason P. Hallett. "Ionic-liquid-processed keratin-based biocomposite films with cellulose and chitin for sustainable dye removal". RSC Sustainability (2024): https://doi.org/10.1039/D4SU00179F.
    10.1039/D4SU00179F
  24. Leonardo M. de Souza Mesquita; Leticia S. Contieri; Francisca A. e Silva; Rafael Henrique Bagini; Felipe S. Bragagnolo; Monique M. Strieder; Filipe H. B. Sosa; et al. "Path2Green: introducing 12 green extraction principles and a novel metric for assessing sustainability in biomass valorization". Green Chemistry (2024): https://doi.org/10.1039/D4GC02512A.
    10.1039/D4GC02512A
  25. Inês S. Cardoso; Filipe H.B. Sosa; Armando J.D. Silvestre; Anthony Robert; Mara G. Freire; Aminou Mohamadou. "Aqueous biphasic systems comprising analogues of glycine-betaine ionic liquids: Toward greener separation platforms". Sustainable Chemistry and Pharmacy (2023): https://doi.org/10.1016/j.scp.2023.101132.
    10.1016/j.scp.2023.101132
  26. Ana M. Ferreira; Maria V. Quental; Mukesh Sharma; Dibyendu Mondal; Augusto Q. Pedro; João A.P. Coutinho; Mara G. Freire. "Towards the improved monitoring of bacterial infections by the isolation of DNA from human serum using ionic-liquid-based aqueous biphasic systems". Separation and Purification Technology (2023): https://doi.org/10.1016/j.seppur.2023.123801.
    10.1016/j.seppur.2023.123801
  27. Emanuel V. Capela; Ilaria Magnis; Ana F.C.S. Rufino; Mario A. Torres-Acosta; M. Raquel Aires-Barros; João A.P. Coutinho; Ana M. Azevedo; Francisca A. e Silva; Mara G. Freire. "Using three-phase partitioning for the purification and recovery of antibodies from biological media". Separation and Purification Technology (2023): https://doi.org/10.1016/j.seppur.2023.123823.
    10.1016/j.seppur.2023.123823
  28. Teresa B.V. Dinis; Ana I. Valente; Ana P.M. Tavares; Fani Sousa; Mara G. Freire. "Integrated platform resorting to ionic liquids comprising the extraction, purification and preservation of DNA". Separation and Purification Technology (2023): https://doi.org/10.1016/j.seppur.2023.123646.
    10.1016/j.seppur.2023.123646
  29. Ana F.C.S. Rufino; Joana M. Bola; Emanuel V. Capela; João A. P. Coutinho; Francisca A. e Silva; Mara G. Freire. "Double-Stimuli-Responsive (Temperature and pH) Aqueous Biphasic Systems Comprising Ionic Liquids". ACS Sustainable Chemistry & Engineering (2023): https://doi.org/10.1021/acssuschemeng.3c00059.
    10.1021/acssuschemeng.3c00059
  30. Filipa C. Flora; Sofia B. Relvas; Francisca A. e Silva; Mara G. Freire; Virginia Chu; João Pedro Conde. "Combined Use of Ionic Liquid-Based Aqueous Biphasic Systems and Microfluidic Devices for the Detection of Prostate-Specific Antigen". Biosensors (2023): https://doi.org/10.3390/bios13030334.
    10.3390/bios13030334
  31. Carlos M. N. Mendonça; Nathalia V. Veríssimo; Wellison A. Pereira; Paula M. Cunha; Michele Vitolo; Attilio Converti; Kiki Adi Kurnia; et al. "Use of Tunable Copolymers in Aqueous Biphasic Systems for Extractive Bioconversion Aimed at Continuous Fructooligosaccharide Production". ACS Sustainable Chemistry & Engineering (2023): https://doi.org/10.1021/acssuschemeng.2c04147.
    10.1021/acssuschemeng.2c04147
  32. Cariny Polesca; Helena Passos; Bruno M. Neves; João A. P. Coutinho; Mara G. Freire. "Valorization of chicken feathers using aqueous solutions of ionic liquids". Green Chemistry (2023): https://doi.org/10.1039/D2GC04477C.
    10.1039/D2GC04477C
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  262. Freire, M.G.; Ventura, S.P.M.; Santos, L.M.N.B.F.; Marrucho, I.M.; Coutinho, J.A.P.. "Evaluation of COSMO-RS for the prediction of LLE and VLE of water and ionic liquids binary systems". Fluid Phase Equilibria 268 1-2 (2008): 74-84. http://www.scopus.com/inward/record.url?eid=2-s2.0-54249108531&partnerID=MN8TOARS.
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  263. Amaral, P.F.F.; Freire, M.G.; Rocha-Leão, M.H.M.; Marrucho, I.M.; Coutinho, J.A.P.; Coelho, M.A.Z.. "Optimization of oxygen mass transfer in a multiphase bioreactor with perfluorodecalin as a second liquid phase". Biotechnology and Bioengineering 99 3 (2008): 588-598. http://www.scopus.com/inward/record.url?eid=2-s2.0-38449113596&partnerID=MN8TOARS.
    10.1002/bit.21640
  264. Freire, M.G.; Carvalho, P.J.; Gardas, R.L.; Santos, L.M.N.B.F.; Marrucho, I.M.; Coutinho, J.A.P.. "Solubility of water in tetradecyltrihexylphosphonium-based ionic liquids". Journal of Chemical and Engineering Data 53 10 (2008): 2378-2382. http://www.scopus.com/inward/record.url?eid=2-s2.0-55349119561&partnerID=MN8TOARS.
    10.1021/je8002805
  265. Tomé, L.I.N.; Carvalho, P.J.; Freire, M.G.; Marrucho, I.M.; Fonseca, I.M.A.; Ferreira, A.G.M.; Coutinho, J.A.P.; Gardas, R.L.. "Measurements and correlation of high-pressure densities of imidazolium-based ionic liquids". Journal of Chemical and Engineering Data 53 8 (2008): 1914-1921. http://www.scopus.com/inward/record.url?eid=2-s2.0-54249138161&partnerID=MN8TOARS.
    10.1021/je800316b
  266. Gardas, R.L.; Costa, H.F.; Freire, M.G.; Carvalho, P.J.; Marrucho, I.M.; Fonseca, I.M.A.; Ferreira, A.G.M.; Coutinho, J.A.P.. "Densities and derived thermodynamic properties of imidazolium-, pyridinium-, pyrrolidinium-, and piperidinium-based ionic liquids". Journal of Chemical and Engineering Data 53 3 (2008): 805-811. http://www.scopus.com/inward/record.url?eid=2-s2.0-49549122979&partnerID=MN8TOARS.
    10.1021/je700670k
  267. Freire, M.G.; Ferreira, A.G.M.; Fonseca, I.M.A.; Marrucho, I.M.; Coutinho, J.A.P.. "Viscosities of liquid fluorocompounds". Journal of Chemical and Engineering Data 53 2 (2008): 538-542. http://www.scopus.com/inward/record.url?eid=2-s2.0-41749101588&partnerID=MN8TOARS.
    10.1021/je700632z
  268. Freire, M.G.; Carvalho, P.J.; Gardas, R.L.; Marrucho, I.M.; Santos, L.M.N.B.F.; Coutinho, J.A.P.. "Mutual solubilities of water and the [Cnmim][Tf2N] hydrophobic ionic liquids". Journal of Physical Chemistry B 112 6 (2008): 1604-1610. http://www.scopus.com/inward/record.url?eid=2-s2.0-39849096285&partnerID=MN8TOARS.
    10.1021/jp7097203
  269. Freire, M.G.; Santos, L.M.N.B.F.; Fernandes, A.M.; Coutinho, J.A.P.; Marrucho, I.M.. "An overview of the mutual solubilities of water-imidazolium-based ionic liquids systems". Fluid Phase Equilibria 261 1-2 (2007): 449-454. http://www.scopus.com/inward/record.url?eid=2-s2.0-35348925299&partnerID=MN8TOARS.
    10.1016/j.fluid.2007.07.033
  270. Gardas, R.L.; Freire, M.G.; Caryalho, P.J.; Marrucho, I.M.; Fonseca, I.M.A.; Ferreira, A.G.M.; Coutinho, J.A.P.. "High-pressure densities and derived thermodynamic properties of imidazolium-based ionic liquids". Journal of Chemical and Engineering Data 52 1 (2007): 80-88. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847072279&partnerID=MN8TOARS.
    10.1021/je060247x
  271. Oliveira, M.B.; Freire, M.G.; Marrucho, I.M.; Kontogeorgis, G.M.; Queimada, A.J.; Coutinho, J.A.P.. "Modeling the liquid-liquid equilibria of water + fluorocarbons with the cubic-plus-association equation of state". Industrial and Engineering Chemistry Research 46 4 (2007): 1415-1420. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847682680&partnerID=MN8TOARS.
    10.1021/ie061147n
  272. Freire, M.G.; Carvalho, P.J.; Fernandes, A.M.; Marrucho, I.M.; Queimada, A.J.; Coutinho, J.A.P.. "Surface tensions of imidazolium based ionic liquids: Anion, cation, temperature and water effect". Journal of Colloid and Interface Science 314 2 (2007): 621-630. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548032548&partnerID=MN8TOARS.
    10.1016/j.jcis.2007.06.003
  273. Freire, M.G.; Santos, L.M.N.B.F.; Marrucho, I.M.; Coutinho, J.A.P.. "Evaluation of COSMO-RS for the prediction of LLE and VLE of alcohols + ionic liquids". Fluid Phase Equilibria 255 2 (2007): 167-178. http://www.scopus.com/inward/record.url?eid=2-s2.0-34249281602&partnerID=MN8TOARS.
    10.1016/j.fluid.2007.04.020
  274. Freire, M.G.; Neves, C.M.S.S.; Carvalho, P.J.; Gardas, R.L.; Fernandes, A.M.; Marrucho, I.M.; Santos, L.M.N.B.F.; Coutinho, J.A.P.. "Mutual solubilities of water and hydrophobic ionic liquids". Journal of Physical Chemistry B 111 45 (2007): 13082-13089. http://www.scopus.com/inward/record.url?eid=2-s2.0-36649021322&partnerID=MN8TOARS.
    10.1021/jp076271e
  275. Gardas, R.L.; Freire, M.G.; Carvalho, P.J.; Marrucho, I.M.; Fonseca, I.M.A.; Ferreira, A.G.M.; Coutinho, J.A.P.. "P¿T measurements of imidazolium-based ionic liquids". Journal of Chemical and Engineering Data 52 5 (2007): 1881-1888. http://www.scopus.com/inward/record.url?eid=2-s2.0-34948868461&partnerID=MN8TOARS.
    10.1021/je700205n
  276. Freire, M.G.; Carvalho, P.J.; Queimada, A.J.; Marrucho, I.M.; Coutinho, J.A.P.. "Surface tension of liquid fluorocompounds". Journal of Chemical and Engineering Data 51 5 (2006): 1820-1824. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749835714&partnerID=MN8TOARS.
    10.1021/je060199g
  277. Freire, M.G.; Gomes, L.; Santos, L.M.N.B.F.; Marrucho, I.M.; Coutinho, J.A.P.. "Water solubility in linear fluoroalkanes used in blood substitute formulations". Journal of Physical Chemistry B 110 45 (2006): 22923-22929. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751206835&partnerID=MN8TOARS.
    10.1021/jp0622942
  278. Freire, M.G.; Dias, A.M.A.; Coutinho, J.A.P.; Coelho, M.A.Z.; Marrucho, I.M.. "Enzymatic method for determining oxygen solubility in perfluorocarbon emulsions". Fluid Phase Equilibria 231 1 (2005): 109-113. http://www.scopus.com/inward/record.url?eid=2-s2.0-17644415395&partnerID=MN8TOARS.
    10.1016/j.fluid.2005.01.008
  279. Freire, M.G.; Razzouk, A.; Mokbel, I.; Jose, J.; Marrucho, I.M.; Coutinho, J.A.P.. "Solubility of hexafluorobenzene in aqueous salt solutions from (280 to 340) K". Journal of Chemical and Engineering Data 50 1 (2005): 237-242. http://www.scopus.com/inward/record.url?eid=2-s2.0-12344300603&partnerID=MN8TOARS.
    10.1021/je049707h
  280. Freire, M.G.; Dias, A.M.A.; Coelho, M.A.Z.; Coutinho, J.A.P.; Marrucho, I.M.. "Aging mechanisms of perfluorocarbon emulsions using image analysis". Journal of Colloid and Interface Science 286 1 (2005): 224-232. http://www.scopus.com/inward/record.url?eid=2-s2.0-17644389912&partnerID=MN8TOARS.
    10.1016/j.jcis.2004.12.036
  281. Dias, A.M.A.; Freire, M.; Coutinho, J.A.P.; Marrucho, I.M.. "Solubility of oxygen in liquid perfluorocarbons". Fluid Phase Equilibria 222-223 (2004): 325-330. http://www.scopus.com/inward/record.url?eid=2-s2.0-4344701296&partnerID=MN8TOARS.
    10.1016/j.fluid.2004.06.037
Capítulo de livro
  1. Cardoso, Inês S.; Pedro, Augusto Q.; Silvestre, Armando J. D.; Freire, Mara G.. "Ionic Liquids and Deep Eutectic Solvents in the Field of Environmental Monitoring". In Green Chemistry and Sustainable Technology, 203-240. Springer Singapore, 2019.
    10.1007/978-981-13-9105-7_8
  2. Bernardo, Sandra C.; Sousa, Ana C. A.; Neves, Márcia C.; Freire, Mara G.. "Use of Nanomaterials in the Pretreatment of Water Samples for Environmental Analysis". In Nanomaterials for Healthcare, Energy and Environment, 103-142. Springer Singapore, 2019.
    10.1007/978-981-13-9833-9_6
  3. Pedro, Augusto Q.; Coutinho, João A. P.; Freire, Mara G.. "Immobilization of Ionic Liquids, Types of Materials, and Applications". In Encyclopedia of Ionic Liquids, 1-12. Springer Singapore, 2019.
    10.1007/978-981-10-6739-6_86-1
  4. Capela, Emanuel V.; Coutinho, João A. P.; Freire, Mara G.. "Application of Ionic Liquids in Separation and Fractionation Processes". In Green Chemistry and Chemical Engineering, 637-665. Springer New York, 2019.
    10.1007/978-1-4939-9060-3_1005
  5. Neves, Catarina M.S.S.; Barbosa, Luís; Coutinho, João A.P.; Freire, Mara G.. "Aqueous biphasic systems formed by cholinium-based ionic liquids and mixtures of polymers". In Ionic Liquids, 29-54. De Gruyter, 2019.
    10.1515/9783110583632-003
  6. Capela, Emanuel V.; Coutinho, João A. P.; Freire, Mara G.. "Application of Ionic Liquids in Separation and Fractionation Processes". In Encyclopedia of Sustainability Science and Technology, 1-29. Springer New York, 2018.
    10.1007/978-1-4939-2493-6_1005-1
  7. Belchior, Diana C. V.; Duarte, Iola F.; Freire, Mara G.. "Ionic Liquids in Bioseparation Processes". In Advances in Biochemical Engineering/Biotechnology, 1-29. Springer International Publishing, 2018.
    10.1007/10_2018_66
  8. Lima, Á.S.; Placido, N.S.O.; França, R.L.S.; Reis, I.A.O.; Pereira, M.M; Mara G. Freire. "Aplicação de Sistemas Aquosos Bifásicos na Purificação de Biomoléculas". In Processos de Extração e Purificação de Biomoléculas, editado por Á.S. Lima; C.C. Santana. 2017.
  9. Quental, M.V.; Almeida, M.R.; Gomes, J.; Resende, J.; Domigues, P.; Mara G. Freire. "Imunoglobulina Y (IgY): uma Alternativa Promissora aos Anticorpos de Mamíferos". In Bioquímica e Bem-Estar, editado por Manuel A. Coimbra. Edições Afrontamento, 2017.
  10. Capela, E.V.; Aires-Barros, M.R.; Mara G. Freire; Azevedo, A.M.. "Monoclonal Antibodies – Addressing the Challenges on the Manufacturing Processing of an Advanced Class of Therapeutic Agents". In Frontiers in Clinical Drug Research-Anti-Infectives. Bentham Science, 2017.
  11. Freire, Mara G.. "Introduction to Ionic-Liquid-Based Aqueous Biphasic Systems (ABS)". In Ionic-Liquid-Based Aqueous Biphasic Systems, 1-25. Springer Berlin Heidelberg, 2016.
    10.1007/978-3-662-52875-4_1
  12. Pereira, Matheus M.; Coutinho, João A. P.; Freire, Mara G.. "Ionic Liquids as Efficient Tools for the Purification of Biomolecules and Bioproducts from Natural Sources". In Ionic Liquids in the Biorefinery Concept, 227-257. Royal Society of Chemistry, 2016.
    10.1039/9781782622598-00227
  13. Marrucho, Isabel M.; Freire, Mara G.. "Aqueous Biphasic Systems Based on Ionic Liquids for Extraction, Concentration and Purification Approaches". In Ionic Liquids for Better Separation Processes, 91-119. Springer Berlin Heidelberg, 2015.
    10.1007/978-3-662-48520-0_5
  14. Freiré, M. G.; Santos, L. M. N. B. F.; Marrucho, I. M.; Coutinho, J. A. P.. "Predicting the Thermodynamic Behaviour of Water + Ionic Liquids Systems Using COSMO-RS". In Molten Salts and Ionic Liquids, 101-121. John Wiley & Sons, Inc., 2012.
    10.1002/9780470947777.ch8
Edição de livro
  1. Mara G. Freire, ed. Ionic-Liquid-Based Aqueous Biphasic Systems. Springer Berlin Heidelberg. 2016.
    10.1007/978-3-662-52875-4
Livro
  1. Pereira, M.M.; Coutinho, J.A.P.; Freire, M.G.. CHAPTER 8: Ionic liquids as efficient tools for the purification of biomolecules and bioproducts from natural sources. 2016.
    10.1039/9781782622598-00227
  2. Freiré, M.G.; Santos, L.M.N.B.F.; Marrucho, I.M.; Coutinho, J.A.P.. Predicting the Thermodynamic Behaviour of Water + Ionic Liquids Systems Using COSMO-RS. 2012.
    10.1002/9780470947777.ch8
Pré-impressão
  1. Adriana Olejniczak; Mara G. Freire; Michal Niemczak. "Structure–Permeability Relationships of Vitamin-B-Based Quaternary Ammonium Salts for Oral Drug Development". 2026. https://doi.org/10.2139/ssrn.6225237.
    10.2139/ssrn.6225237
  2. Adriana Olejniczak; Daniela Gwiazdowska; Krzysztof Jus; Anna Olejnik; Mara G. Freire; Michal Niemczak. "Quaternary ammonium salts derived from Vitamin B as multifunctional (anti-inflammatory and antimicrobial) therapeutic agents ¿". 2026. https://doi.org/10.2139/ssrn.6428126.
    10.2139/ssrn.6428126

Propriedade Intelectual

Pedido provisório de patente
  1. 2018. "Kit Diagnóstico de Câncer através da Urina por Meio de Sistemas Aquosos Bifásicos baseados em Líquidos Iónicos".
    Divulgado
  2. 2018. "Processo para extrair, concentrar e purificar um antigénio a partir de uma amostra biológica não invasiva, composição e seus usos".
    Divulgado
  3. 2018. "Adsorvente magnético para remover um composto púrico de uma matriz líquida e método para a sua preparação".
    Divulgado
  4. 2018. "Purificação de imunoglobulina Y".
    Divulgado
  5. 2018. "Processo para purificar um anticorpo a partir da gema de ovo".
    Divulgado
  6. 2018. "Separação de Ácidos Nucleicos utilizando Líquidos Iónicos como Ligandos Cromatográficos Multimodais em Matrizes Macroporosas".
    Divulgado
  7. 2017. "Kit Diagnóstico de Câncer através da Urina por Meio de Sistemas Aquosos Bifásicos baseados em Líquidos Iónicos".
    Divulgado
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2019 Downstream of Biopharmaceuticals using Ionic-Liquid-based Strategies BPP 2019 - Biopartitioning & Purification Conference
(Guarujá, Brasil)
2019 Purification of Biopharmaceuticals using Ionic-Liquid-based Strategies ILSILSEPT - 4th International Conference on Ionic Liquids in Separation and Purification Technology
(Sitges, Espanha)
2019 Water, Ionic Liquids and Salts: From the salting-out phenomenon to the formation of aqueous two-phase systems XXVI Encontro Nacional da Sociedade Portuguesa de Química
2018 Purification of Biopharmaceuticals using Ionic-Liquid-based Strategies ”, III Encontro Biotecnologia Medicinal/1st Iberian Congress on Medicinal Biotechnology
2017 Purification of Bioactive and Value-added Compounds using Ionic-Liquid-based Strategies Microbiotec 2017
2017 Cost-Efficient Extraction and Purification Technologies for Proteins based on Ionic Liquids CNC/UC-Biotech Fall Series 2017
2017 Ionic-Liquid-Based Separation Processes for Bioactive and Value-Added Compounds XXV Encontro Nacional da Sociedade Portuguesa de Química
2017 Design of Effective Purification Platforms for Biopharmaceuticals EurASc 2017 Symposium
2017 Ionic-Liquid-based Strategies for the Purification and Concentration of Proteins III Encontro Nacional de Estudantes de Biotecnologia
2016 Boosting the Applications of (Ionic-Liquid-based) Aqueous Biphasic Systems: from the Purification of Biopharmaceuticals towards the Concentration of Cancer Biomarkers 26th EUCHEM Conference on Molten Salts and Ionic Liquids
(Viena, Áustria)
2016 Thorough the Thrilling World of Ionic Liquids by the Combination of Experimental and Computational Approaches XII Encontro Nacional de Química-Física
2015 Ionic Liquids as Alternative Solvents for the Extraction, Purification and Concentration of High-Value Proteins: from Biopharmaceuticals to Cancer Biomarkers Iberoamerican Meeting on Ionic Liquids (IMIL 2015)
(Madrid, Espanha)
2015 Aqueous Biphasic Systems Composed of Ionic Liquids for Pharmaceutical- and Biotechnological-related Separations 6th Congress on Ionic Liquids, COIL-5
(Jeju, Coreia do Sul)
2015 Extraction, Purification and Concentration of Value-Added Proteins: Recent Advances using Ionic-Liquid-based Aqueous Biphasic Systems EXIL Workshop
(Praga, República Checa)
2015 Purification and Concentration of Proteins using Ionic Liquids: From Diagnostic to Biopharmaceutical Applications 2nd EuCheMS Congress on Green and Sustainable Chemistry
2014 Liquid-Liquid Phase Behavior of Ionic Liquids and Aqueous Solutions NETZSCH Young Scientist Award, 20th European Conference on Thermophysical Properties, ECTP 2014
(Porto, Portugal)
2014 Aqueous Biphasic Systems Composed of Ionic Liquids: Towards the Understanding of their Formation Ability Liquid/liquid extraction with Ionic Liquids Workshop
(Strasbourg, França)
2014 Ionic Liquids in Pharmaceutical and Biotechnological Applications Workshop Nano14 - Shaping the Future
2014 Extraction and Purification of Value-Added Biomolecules using Ionic Liquids 4th Portuguese Young Chemists Meeting: 4 PYCheM
2013 Aqueous biphasic systems composed of ionic liquids: formation ability and extractive performance Lectures in Physical-Chemistry
2011 Phase Equilibria of Ionic Liquids in Aqueous Environments XXI Encontro Nacional da Sociedade Portuguesa de Química (SPQ)
2011 Do We Already Know Everything? 4th Congress on Ionic Liquids
2011 Biomolecules Separation using Aqueous Biphasic Systems Composed of Polyethylene Glycols and Ionic Liquids 1st International Conference on Ionic Liquids in Separation and Purification Technology
2011 Biphasic Liquid-Liquid Systems based on Ionic Liquids and Polyethylene Glycols 241st ACS National Meeting
2009 On the Molecular Basis of the Salting-in of Ionic Liquids (and Other Molecules) in Aqueous Solution Seventeenth Symposium on Thermophysical Properties

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2019/09 - Atual Integrated process for the production and purification of monoclonal antibodies fragments
Orientador de Correia, A. S.
 Bioquímica (Mestrado)
Universidade de Aveiro, Portugal
2019/06/01 - Atual Development of ionic-liquid-based devices for the removal of cytostatic drugs from urine excreted by cancer patients (researcher contract)
Orientador de Silva, A. F. O. A. C.
Universidade de Aveiro, Portugal
2018/10/01 - Atual Magnetic-responsive Aqueous Biphasic Systems as Alternative Pretreatment Strategies of Biological Fluids
Orientador de Rufino, A. F.
 Engenharia Química (Doutoramento)
Universidade de Aveiro, Portugal
2018/10/01 - Atual Pretreatment of Human Serum using Ionic-Liquid-based Three-Phase Partition Systems to Improve Diagnosis and Prognosis
Orientador de Rosa, M. E.
 Engenharia Química (Doutoramento)
Universidade de Aveiro, Portugal
2018/10 - Atual Integrated Recovery Processes of High-Value Bioactive Compounds from Agroforest By-Products using Aqueous Solutions of Bio-based Ionic Liquids
Orientador de Cardoso, I. S.
Universidade de Aveiro, Portugal
2018/10 - Atual Development of Ionic-Liquid-based Devices for the Removal of Cytostatic Drugs from Urine Excreted by Cancer Patients
Orientador de Francisco, R.
Universidade de Aveiro, Portugal
2018/10 - Atual Ionic-Liquid-Supported Magnetic Nanomaterials for the Recovery of High Economic Value Elements
Coorientador de Almeida, J. C.
Universidade de Aveiro, Portugal
2017/09/01 - Atual Deep Eutectic Solvents as Efficient Media for the Extraction of Polysaccharides in Biorefinery Processes
Coorientador de Morais, E.
 Engenharia Química (Doutoramento)
Universidade de Aveiro, Portugal
2017/09 - Atual Deep Eutectic Solvents as Acctive Pharmaceutical Ingredients in Biopolymer-based Drug Delivery Systems
Coorientador de Pedro, S. I. N.
Universidade de Aveiro, Portugal
2017/05/01 - Atual Purification of Monoclonal Antibodies (Immunoglobulin G, IgG) using Aqueous Biphasic Systems composed of Bio-based Ionic Liquids
Orientador de Capela, E. V.
 Engenharia Química (Doutoramento)
Universidade de Aveiro, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal
2015/10 - Atual Development of Ionic-Liquid-based Supported Materials for the Purification of Ribonucleic Acid (RNA)
Orientador de Dinis, T. V.
Universidade de Aveiro, Portugal

Universidade da Beira Interior, Portugal
2019/09/01 - 2020/07/13 Nox1-inhibitor-based therapeutic approach to prevent Parkinson’s Disease progression
Coorientador de Diogo, J.
 Biotecnologia (Mestrado)
Universidade da Beira Interior, Portugal

Universidade de Aveiro, Portugal
2018/09/15 - 2019/12/19 Removal of purines with sustainable magnetic materials
Orientador de Santos, A. C. A.
 Bioquímica (Mestrado)
Universidade de Aveiro, Portugal
2018/09/01 - 2019/12/19 Removal of cytostatics using supported ionic liquids
Orientador de Santos, M. J. G.
 Bioquímica (Mestrado)
Universidade de Aveiro, Portugal
2018/09 - 2019/12/19 Supported ionic liquids for purines removal: a healthier beer
Orientador de Simões, J. M.
 Biotecnologia (Mestrado)
Universidade de Aveiro, Portugal
2018/09/01 - 2019/12/15 Production and purification of anti-human interleukin-8 monoclonal antibodies
Orientador de Bairos, J. C. B.
 Bioquímica (Mestrado)
Universidade de Aveiro, Portugal
2018/09/01 - 2019/12/05 Purification of microRNAs using chromatographic supports modified with ionic liquids
Coorientador de Carapito, R.
 Bioquímica (Mestrado)
Universidade da Beira Interior, Portugal

Universidade de Aveiro, Portugal
2019/02/01 - 2019/07/15 Development of thermoreversible aqueous biphasic systems for the processing of biopharmaceuticals
Coorientador de Silva, R. G.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2019/02 - 2019/05 Development of new integrated platforms for the production and purification of biopharmaceuticals (post-doctoral fellow)
Orientador de Silva, A. F. O. A. C.
Universidade de Aveiro, Portugal
2015/10 - 2019/03 Post-doctoral grant on the characterization of novel reversible ionic-liquid-based aqueous biphasic systems and their use for fractionation of complex mixtures
Coorientador de Neves, C. M. S. S.
Universidade de Aveiro, Portugal
2018/10/01 - 2019/01/30 Lliquid-liquid phase equilibria of aqueous biphasic systems composed of mixtures of ionic liquids and their application in the separation of antibodies (post-doctoral fellow)
Orientador de Passos, H.
Universidade de Aveiro, Portugal
2018/10 - 2019/01 Stability of antibodies in aqueous solutions of ionic liquids (post-doctoral fellow)
Orientador de Silva, A. F. O. A. C.
Universidade de Aveiro, Portugal
2019 - 2019 Purification of therapeutic antibodies from human serum using pear graphene aerogels
Orientador de Fonseca, A. B. L.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2018 - 2019 Application of newly synthesized ionic liquids for the extraction of selected pharmaceuticals
Coorientador de Kopilovic, B.
Universidade de Novi Sad, Sérvia

Universidade de Aveiro, Portugal
2015 - 2019 Application of aqueous biphasic systems for the separation of amino acids and proteins
Orientador de Belchior, D. C. V.
Universidade de Aveiro, Portugal
2015 - 2019 Aqueous biphasic systems for the purification and preservation of biologically active compounds
Orientador de Quental, M. V.
Universidade de Aveiro, Portugal
2015 - 2019 Extraction of value-added compounds from biomass using alternative solvents
Orientador de Faria, E. L. P.
Universidade de Aveiro, Portugal
2018/04/01 - 2018/12/31 Development of new filters (single and double layer) for application in taps of domestic use aiming water treatment (post-doctoral fellow)
Orientador de Rocha, L. S.
Universidade de Aveiro, Portugal
2016/01 - 2018/12 Post-doctoral grant on the development of a cost-effective kit for the extraction and preservation of RNA using ionic liquids
Coorientador de Madeira, P. P.
Universidade de Aveiro, Portugal
2014/02 - 2018/12 Post-doctoral grant on Supported Ionic Liquids for the Purification of Immunoglobulin Y (IgY)
Orientador de Neves, M. C.
Universidade de Aveiro, Portugal
2016/10 - 2018/10 Post-doctoral grant on the synthesis and use of bio-based ionic liquids for the selective extraction and purification of antibodies
Orientador de Sharma, M.
Universidade de Aveiro, Portugal

Central Salt & Marine Chemicals Research Institute, Índia
2017/10 - 2018/09 MultiRespira - Multidisciplinary approach to understand the role of environmental contaminants in respiratory diseases in Estarreja Region (post-doctoral fellow)
Coorientador de Sousa, A. C. A.
Aix-Marseille Université, França

Universidade do Porto Instituto de Saúde Pública, Portugal

Universidade da Beira Interior, Portugal

Universidade de Aveiro, Portugal
2018/02/01 - 2018/07/15 Purification of Therapeutic Monoclonal Antibodies using Alternative Platforms
Orientador de Santiago, A. F. E.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2018/02/01 - 2018/07/15 New Liquid Carriers based on Ionic Liquids and Water for Oxidative Enzymes Reuse
Coorientador de Valente, A. I.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2017/09 - 2018/07 Cultivation of Mediterranean Plants in Technosols from Mining Areas and their Exploration as Sources of Natural Value-Added Compounds (post-doctoral fellow)
Orientador de Santos, E. S.
Universidade de Aveiro, Portugal

Universidade de Lisboa Instituto Superior de Agronomia, Portugal

Universidade de Santiago de Compostela, Espanha
2016/09 - 2018/03 Post-Doctoral grant on recombinant expression of different Campylobacter jejuni colonization-associated proteins and their purification for hen immunization
Orientador de Pedro, A. Q. H.
Universidade de Aveiro, Portugal
2018 - 2018 Aqueous Biphasic Systems as Alternative Platforms for Antioxidants Recovery from Food Residues
Coorientador de Ferreira, M.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2018 - 2018 Removal of Bisphenol A with Supported Ionic liquids
Coorientador de Sousa, G. L.
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2018 - 2018 Integrated Technology with Biocatalysis for the Removal and Treatment of Persistent Pollutants from Aqueous Effluents
Coorientador de Bento, R. M. F.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2018 - 2018 Concentration of cortisol using aqueous biphasic systems formed by ionic liquids
Orientador de Silva, F.
 Química (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2017 - 2018 Testing the Application of New Chemical Formulations for Neurological Disease Therapies
Coorientador de David, E. S.
Universidade da Beira Interior, Portugal

Universidade de Aveiro, Portugal
2017 - 2018 Novel Purification Strategies for microRNAs using Ionic Liquid
Coorientador de Rodrigues, I.
Universidade da Beira Interior, Portugal

Universidade de Aveiro, Portugal
2017 - 2018 Removal of Cytostatic Drugs from Urine using Ionic-Liquid-based Materials
Orientador de Rocha, B.
Universidade de Aveiro, Portugal
2014 - 2018 Development of Purification Platforms for Immunoglobulin Y using Aqueous Biphasic Systems
Orientador de Almeida, A. M. R.
Universidade de Aveiro, Portugal
2014 - 2018 Purification Strategies for Polyclonal Antibodies from Egg Yolk
Orientador de Bernardo, S. C. S.
Universidade de Aveiro, Portugal
2014 - 2018 Ionic Liquids Aqueous Solutions as Sustainable Solvents in Separation Processes
Orientador de Ferreira, A. M.
Universidade de Aveiro, Portugal
2015/12 - 2017/08 Post-doctoral grant on the study of antibodies stability in the presence of ionic liquids
Orientador de Mondal, D.
Universidade de Aveiro, Portugal
2017/02/01 - 2017/07/15 Purification of Antibodies (Imunoglobulina G, IgG) using Hybrid Biopolymer-based Nanomaterials (Fe3O4@SiO2/SiCRG)
Orientador de Magalhães, F.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2014/07 - 2017/06 Post-doctoral grant on the Purification of Antibodies (Immunoglobulin Y, IgY) using Aqueous Biphasic Systems Composed of Novel Ionic Liquids with Buffering Characteristics
Orientador de Tavares, A. P. M.
Universidade de Aveiro, Portugal
2016/01 - 2017/01 Post-Doctoral grant on the Extraction of Egg White Proteins using Ionic-Liquid-based Aqueous Biphasic Systems
Coorientador de Sousa, R. C. S.
Universidade de Aveiro, Portugal
2017 - 2017 Purification and Stabilization of DNA using Ionic-Liquid-based Aqueous Biphasic Systems
Orientador de Machado, A. R. P.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2017 - 2017 Concentration of cortisol from biological fluids applying aqueous biphasic systems
Orientador de Mendes, C. S. M.
 Bioquí­mica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2017 - 2017 Purification of Immunoglobulin G from Human Plasma using Aqueous Micellar Two-Phase Systems
Orientador de Barros, J. C. B.
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2017 - 2017 Development of Biocompatible Aqueous Biphasic Systems for the Purification of Biopharmaceuticals
Orientador de Santos, R. F.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2016 - 2017 Formation of Protein Aggregates in Presence of Ionic Liquids and Application of Dynamic Molecular Simulations
Coorientador de Rufino, A.
Universidade de Aveiro, Portugal
2016 - 2017 Purification of miRNA using Ionic-Liquid-based Strategies
Coorientador de Martins, J. C.
Universidade da Beira Interior, Portugal

Universidade de Aveiro, Portugal
2016 - 2017 Production and Purification of Interferon alpha-2b from Escherichia coli Cultures using Alternative Platforms
Orientador de Antunes, J. R. M.
Universidade de Aveiro, Portugal
2016 - 2017 Production and Purification of IgY Antibodies with Antimicrobial Properties
Orientador de Rosa, M. E.
Universidade de Aveiro, Portugal

Biocant Associação de Transferência de Tecnologia, Portugal
2016 - 2017 Antibodies Purification using Centrifugal Partition Chromatograph
Orientador de Ferreira, F.
Universidade de Aveiro, Portugal
2016 - 2017 Extraction and Purification of Immunoglobulin G using Aqueous Biphasic Systems Constituted by Ionic Liquids as Adjuvants
Orientador de Amorim, A. P. D.
Universidade de Aveiro, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal
2013 - 2017 Ionic-Liquid-based Aqueous Biphasic Systems as Concentration and Purification Platforms of Cancer Biomarkers
Orientador de Pereira, M. M.
Universidade de Aveiro, Portugal
2013 - 2017 Treatment of Aqueous Effluents Contaminated with Active Pharmaceutical Ingredients
Coorientador de Almeida, H. F. D.
Universidade de Aveiro, Portugal

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2013 - 2017 Development and Characterization of New Extraction Platforms using Ionic-Liquid-based Aqueous Biphasic Systems
Coorientador de Passos, H. I. S.
Universidade de Aveiro, Portugal
2015/06 - 2016/06 Post-doctoral grant on the Purification of Anthocyanins from Grape Pomace
Coorientador de Lima, A. S.
Universidade de Aveiro, Portugal

Technische Universitat Wien TVFA GmbH, Áustria
2015/01 - 2016/06 Post-doctoral grant on the Purification of Antibodies using Aqueous Biphasic Systems
Orientador de Pankaj, B.
Universidade de Aveiro, Portugal
2014/10 - 2016/05 Post-doctoral grant on the Extraction and Purification of High-Value Bioactive Compounds from Agroforestry Biomass Residues using Aqueous Solutions of Ionic Liquids
Coorientador de Cláudio, A. F. M.
Universidade de Aveiro, Portugal
2016 - 2016 Solubility of Proteins in Aqueous Solutions of Ionic Liquids
Orientador de de Sá, I. M.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2016 - 2016 Development of Biocompatible Aqueous Biphasic Systems for the Purification of Biopharmaceuticals
Orientador de Ramalho, A. C. C.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2016 - 2016 Purification of Antibodies using Carbon-based Nanomaterials
Orientador de Marques, A. M. F.
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2016 - 2016 Purification of Antibodies (Immunoglobulin Y, IgY) using Carbon Nanomaterials
Orientador de Ribeiro, D. R. P.
 Química (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2016 - 2016 Purification of Oxidative Enzymes using Aqueous Biphasic Systems
Orientador de Santos, J. P. F.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2015 - 2016 Development of aqueous micellar two-phase systems for the selective extraction and purification of IgG from real matrices
Orientador de Costa, S. H. S.
Universidade de Aveiro, Portugal
2015 - 2016 Removal of Persistent Pollutants using Silica Modified with Ionic Liquids
Orientador de Azevedo, S. C. S.
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade de Aveiro, Portugal
2015 - 2016 Cynaropicrin Extraction from Cultivated Cardoon using Deep Eutectic Solvents
Orientador de Carmo, R. S.
Universidade de Aveiro, Portugal
2015 - 2016 Extraction and Recovery of Cynaropicrin from Cynara cardunculus L. using Ionic Liquids Aqueous Solutions
Orientador de Gomes, M. V
Universidade de Aveiro, Portugal
2015 - 2016 Purification of IgY and Evaluation of its Activity/Stability in aqueous Solutions of Polymers, Salts and Ionic Liquids
Orientador de Calheiros, J.
Universidade de Aveiro, Portugal
2015 - 2016 Development of Novel Biomaterials Incorporating Antioxidant and Anti-Inflammatory Ionic Liquids for Topic Applications
Orientador de Morais, E. S.
Universidade de Aveiro, Portugal
2015 - 2016 Purification of Antibodies using Aqueous Biphasic Systems
Orientador de Castro, L. S. O.
Universidade de Aveiro, Portugal
2015 - 2016 Concentration of Cancer Biomarkers using Ionic Liquids
Orientador de Pedro, S. N.
Universidade de Aveiro, Portugal
2015 - 2016 Purification of Immunoglobulin G using Aqueous Biphasic Systems formed by Ionic Liquids
Orientador de Capela, E. V.
Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade de Aveiro, Portugal
2012/01 - 2015/05 Post-doctoral grant on the Comprehensive Study on Ionic-Liquids-Water Interactions
Coorientador de Kurnia, K. A.
Universidade de Aveiro, Portugal
2015 - 2015 New Aqueous Biphasic Systems for Biomolecules Fractionation/Purification
Orientador de Barbosa, L. M. M.
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2015 - 2015 Extraction and Stability of Egg Yolk Antibodies (IgY) using Aqueous Biphasic Systems
Orientador de Ferreira, F. M.
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2015 - 2015 Purification of Antibodies (Immunoglobullin Y, IgY) using Carbon Nanotubes
Orientador de Lameirinhas, N.
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2014 - 2015 Extraction and Purification of Theobromine using Ionic Liquids
Orientador de Esteves, P. D. O.
Universidade de Aveiro, Portugal

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2014 - 2015 Characterization of Mixtures of Fluorinated Ionic Liquids
Orientador de Correia, H. V. T.
Universidade de Aveiro, Portugal

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2014 - 2015 Isolation of Triterpenic Acids from Eucalyptus globulus (bark) using Ionic Liquids
Coorientador de Shabudin, S.
Universidade de Aveiro, Portugal
2014 - 2015 Extraction of Caffeine from Spent Coffee using Aqueous Solutions of Ionic Liquids
Coorientador de Gomes, H.
Universidade de Aveiro, Portugal
2014 - 2015 Solubilization of Membrane Proteins using Ionic Liquids
Orientador de Francisco, R.
Universidade de Aveiro, Portugal

Biocant Associação de Transferência de Tecnologia, Portugal
2014 - 2015 Production of Hyperimmune Egg Samples followed by Fractionation
Orientador de Silva, D. P. G.
Universidade de Aveiro, Portugal

Biocant Associação de Transferência de Tecnologia, Portugal
2014 - 2015 Purification of IgY using Aqueous Biphasic Systems Composed of Good’s Buffers Ionic Liquids
Orientador de Gomes, J. M. M.
Universidade de Aveiro, Portugal
2014 - 2015 Impacto do pH na Purificação de IgY com Sistemas Aquosos Bifásicos
Orientador de Resende, J. S. S.
Universidade de Aveiro, Portugal
2014 - 2015 Extraction and Purification of Immunoglobulin G with Aqueous Biphasic Systems
Orientador de Faustino, V. F. M.
Universidade de Aveiro, Portugal
2014 - 2015 Concentration of Human Pollution Tracers with Ionic Liquids
Orientador de Dinis, T. B. V.
Universidade de Aveiro, Portugal
2014 - 2015 Concentration of tumor biomarkers using aqueous biphasic systems
Orientador de Calixto, J. P. D.
Universidade de Aveiro, Portugal
2014 - 2015 Extraction of Proteins using IL-containing Aqueous Biphasic Systems (ABS)
Coorientador de Hübner, M.
Technische Universität Dortmund, Alemanha

Universidade de Aveiro, Portugal
2012/01 - 2014/12 Post-doctoral grant on the Biomimetic CO2 Sequestration Using Carbonic Anhydrase, Amine-Based Buffers, and Ionic Liquids
Coorientador de Taha, M.
Universidade de Aveiro, Portugal
2014 - 2014 Characterization of Aqueous Two-Phase Systems using Deep-Eutectic Solvents
Coorientador de Tavares, D. J. P.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2014 - 2014 Extraction and Selective Separation of Dyes with Aqueous Multiphasic Systems
Coorientador de Costa, S. H. S.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2014 - 2014 Purification of Antibodies using Aqueous Biphasic Systems
Orientador de Capela, E. A. V.
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2014 - 2014 Aqueous Biphasic Systems composed of Ionic Liquids and Carbohydrates
Orientador de Esteves, P. D. O.
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2014 - 2014 Concentration of Prostate Cancer Biomarkers using Aqueous Biphasic Systems
Orientador de Pedro, S. I. N.
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2013 - 2014 Application of Ionic Liquids in the Concentration of Cancer Biomarkers
Orientador de Quental, M. J. V.
Universidade de Aveiro, Portugal
2013 - 2014 Extraction of Antioxidants with Aqueous Biphasic Systems
Orientador de Vaz, T. S. M.
Universidade de Aveiro, Portugal
2013 - 2014 Identification and Characterization of Eutetic Mixtures Composed of Ionic Liquids
Coorientador de Santos, R. J. B. N
Universidade de Aveiro, Portugal
2010 - 2014 Extraction of Added-Value Products from Biomass using Ionic Liquids
Coorientador de Cláudio, A. F. M.
Universidade de Aveiro, Portugal
2010 - 2014 Evaluation of Environmental Impact and Treatment of Aqueous Effluents Contaminated with Ionic Liquids
Coorientador de Neves, C. M. S. S.
Universidade de Aveiro, Portugal
2013 - 2013 Aqueous Biphasic Systems with Ionic Liquids: Characterization and Application in the Concentration of Synthetic Hormones
Orientador de Dinis, T. B. V.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2012 - 2013 Separation of Dyes with Reversible Aqueous Biphasic Systems
Orientador de Ferreira, A. M.
Universidade de Aveiro, Portugal
2012 - 2013 Aqueous Biphasic Systems Composed of Ionic Liquids and Polysaccharides
Orientador de Carvalho, S. F.
Universidade de Aveiro, Portugal
2012 - 2013 Purification of antibodies using aqueous two-phase systems
Orientador de Almeida, A. M. R.
Universidade de Aveiro, Portugal
2009 - 2013 A Tail of Two Bioprocesses
Coorientador de Pereira, J. F. B.
Universidade de Aveiro, Portugal
2012 - 2012 Solubility of Carbohydrates in Ionic Liquids
Coorientador de Henriques, B. J. M.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2012 - 2012 Extraction and Purification of Antibiotics using Aqueous Two-Phase System
Coorientador de Vicennte, F. A.
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2012 - 2012 Application of Aqueous Two-Phase Systems for the Analysis of Doping Substances
Orientador de Trindade, M. J. de M. S. P.
 Química (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2012 - 2012 Application of Aqueous Two-Phase Systems for the Analysis of Doping Substances
Orientador de Vaz, T. S. M.
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2012 - 2012 Antioxidant Activity and Solubility of Ionic Liquids in Water
Orientador de Rodrigues, A. R. G.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2012 - 2012 Evaluation of the Ionic Liquids Antioxidant Activity and Solubility in Water
Orientador de Pereira, L. S. O.
 Bioquímica (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2011 - 2012 Extraction of bioactive compounds with aqueous solutions of ionic liquids
Coorientador de Passos, H. I. S.
Universidade de Aveiro, Portugal
2011 - 2012 Treatment of Aqueous Effluents Contaminated with Ionic Liquids
Coorientador de Marques, C. F. C.
Universidade de Aveiro, Portugal
2011 - 2011 Production of Polymeric Fibers through Electrospinning using Ionic Liquids
Coorientador de Sardo, N. M. G.
 Biotecnologia (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal
2009 - 2010 Extraction of Phenolic Compounds with Aqueous Two Phase Systems
Coorientador de Cláudio, A. F. M.
Universidade de Aveiro, Portugal
2008 - 2009 Extraction of Biomolecules with Aqueous Two Phases Systems
Coorientador de Louros, C. S.
Universidade de Aveiro, Portugal
2007 - 2007 Mutual Solubilities between Water and Ionic Liquids
Coorientador de Neves, C. M. S. S.
 Química (Licenciatura/Bacharelato)
Universidade de Aveiro, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2024/01/29 Semifluorinated Soft­-Matter: towards triphilic fluids and nano compartmentalised systems
Arguente principal
 Eduardo Jorge Morilla Filipe (Agregação)
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2023/04/01 Hydrophobic eutectic solvents: characterization and application
Arguente principal
 F. B. Peña (Doutoramento)
Universidad de Zaragoza, Espanha
2022/01/02 Potential of Ionic Liquids as Protein Drug Delivery Systems
Arguente principal
 M.M.S. Alves (Doutoramento)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2021/06/06 Development of new strategies for the extraction of biomolecules using aqueous biphasic systems based on ionic liquids
Arguente principal
 F.S. Buarque (Doutoramento)
Universidade de Tiradentes, Brasil
2021/05/05 Characterization of the self-assembling of antimicrobial D,L-a-cyclic peptides at bacterial model membranes
Vogal
 B.M.A.G.M. Claro (Doutoramento)
2021/04/04 Development of microscale immunoassays using aqueous two-phase systems
Arguente principal
 A.G. Teixeira (Doutoramento)
Dalhousie University, Canadá
2021/03/03 NMR investigation of ion-pair modulation of protein structure and dinaymics and their relation to protein stability
Arguente principal
 M.C. Silva (Doutoramento)
Universidade Nova de Lisboa, Portugal
2020/05/05 Development of sustainable platforms for the stabilization and purification of the recombinant Green Fluorescent Protein produced by Escherichia coli
Arguente principal
 N.V. Santos (Doutoramento)
Universidade Estadual Paulista Júlio de Mesquita Filho, Brasil
2020/05/05 Analysis of solute-water interactions by partitioning in multiple aqueous two-phase systems
Arguente principal
 N.M.S.R.M. Silva (Doutoramento)
Universidade do Minho, Portugal
2020/04/03 Development of quaternary aqueous biphasic systems for biomolecules separation and purification
Arguente principal
 M.K. Marchel (Doutoramento)
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2019 Study of plasmid DNA purification conditions in its biological activity for cancer therapy Junior, G.M.A. (Doutoramento)
Universidade da Beira Interior, Portugal
2019 PEGylation strategy to the development of analytical and therapeutic proteins Santos, J.H.P.M. (Doutoramento)
Universidade de Aveiro, Portugal
2019 Using alternative solvents for the extraction of bioactive compounds from Juglans regia L. Vieira, V.A.A. (Doutoramento)
Universidade de Aveiro, Portugal
2019 Exploring the photochromism of Gemini Diarylethene-based Ionic Liquids as a switch of the physico-chemical properties of solutions Soromenho, M.R.C. (Doutoramento)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019 Integrative platforms for downstream processing and detection of viral particles Jacinto, M.J.C. (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019 Fluorinated Ionic Liquids for the Development of New Drug Delivery Systems Vieira, N.S.M. (Doutoramento)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019 Lignocellulosic biomass fractionation with deep eutectic solvents 1. Carvalho, A. M. (Mestrado)
Universidade de Aveiro, Portugal
2019 Implementation and Validation of the Total Organic Carbon Determination Method in Liquid Matrices from the Pulp and Paper Industry
Presidente do júri
 Sacramento, M. M. A. (Mestrado)
Universidade de Aveiro, Portugal
2019 Cascas de frutos secos usadas na recuperação da qualidade de águas
Presidente do júri
 Dias, M. A. S. (Mestrado)
Universidade de Aveiro, Portugal
2018 Affinity purification and delivery of a p53-enconding plasmid DNA foe gene mediated cancer therapy Valente, J.F.P. (Doutoramento)
Universidade da Beira Interior, Portugal
2018 Development of Redox Electrolytes and their Application in New Electrochemical Energy Storage Devices Molina, P.N. (Doutoramento)
Universidad Autónoma de Madrid, Espanha
2018 Capture strategies of human catechol-O-methyltransferase from Komagataella pastoris lysates by gellan microspheres Gonçalves, C. A. G. (Mestrado)
Universidade da Beira Interior, Portugal
2018 High pressure extraction of diterpenes from the seaweed Bifurcaria bifurcata
Presidente do júri
 Pais, A. C. S. (Mestrado)
Universidade de Aveiro, Portugal
2018 Impact of addition of pomegranate peel extract and high-pressure on carrot juice preservation: quality and safety aspects
Presidente do júri
 Trigo, J.P. (Mestrado)
Universidade de Aveiro, Portugal
2018 Differential DNA methylation in Aging: In Silico Exploration using High-Throughput Datasets
Presidente do júri
 Conceição, C.N. (Mestrado)
Universidade de Aveiro, Portugal
2017 Development of Novel Microextraction Analytical Methodologies using New Materials based on Ionic Liquids and their Derivatives Rodríguez, M.J.T. (Doutoramento)
Universidad de La Laguna, Espanha
2017 Multiscale Modeling anf Experimental Studies on Bio-Oil Upgradation Bharti, A. (Doutoramento)
Indian Institute of Technology Guwahati, Índia
2017 Investigation of Assorted Interactions of Vital Compounds in Aqueous Ionic Liquid and Vitamin Solutions and Solvent Arrangements Roy, M.C. (Doutoramento)
University of North Bengal, Índia
2017 Polymorphism in Pharmaceuticals: Avoiding it or Controlling it Recurring to Ionic Liquids Martins, I.C.B. (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 Platelet Lysates Loaded Laminarin Microparticles for Cell Expansion and Attachment
Presidente do júri
 Martins, C.I.R. (Mestrado)
Universidade de Aveiro, Portugal
2017 Bioreactor de perfusão para a análise high-throughput de combinações de biomaterias/células estaminais
Presidente do júri
 Lopes, D.D. (Mestrado)
Universidade de Aveiro, Portugal
2017 Computational Optimization of Bio-Adsorbents for the Removal of Pharmaceuticals from Water
Presidente do júri
 Pereira, J.M.S. (Mestrado)
Universidade de Aveiro, Portugal
2017 Development of a CNVs detection method through qPCR
Presidente do júri
 Eulálio, I.M.C. (Doutoramento)
Universidade de Aveiro, Portugal
2016 Ionic Liquid Pre-Treatment of Microalgae and Extraction of Biomolecules Desai, R.K. (Doutoramento)
Wageningen University and Research Research Institutes, Países Baixos
2016 Magnetic Purification of Antibodies Dhadge, V.L. (Doutoramento)
Universidade Nova de Lisboa, Portugal
2016 Monoliths for purification of a DNA vaccine against Influenza Bicho, D.S.F. (Doutoramento)
Universidade da Beira Interior, Portugal
2016 Synthesis and Purification of Xanthohumol C from Xanthohumol Hop Extract Ramires, M.A.B. (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 Effect of Reactor Configuration in the Acidogenic Fermentation Profile
Presidente do júri
 Runa, V.M.R. (Mestrado)
Universidade de Aveiro, Portugal
2016 New Aqueous Two-Phase Mixed Micellar Systems with Ionic Liquids for the extraction of Phycobiliproteins from Macroalgae
Presidente do júri
 Cardoso, I.C.S. (Mestrado)
Universidade de Aveiro, Portugal
2015 Azeotropic Separation: Playing with the Ionicity of Ionic Liquids Oliveira, F.S.S. (Doutoramento)
Universidade Nova de Lisboa, Portugal
2015 Novel Ionic Liquids for a Sustainable Development Aguete, M.V. (Doutoramento)
Universidade de Vigo, Espanha
2015 Macroalgae as Feedstock for Cultivation of Marine Bacteria
Presidente do júri
 França, L.V. (Mestrado)
Universidade de Aveiro, Portugal
2015 Estudo da Imobilização da Lacase em Nanopartículas Magnéticas e sua Aplicação
Presidente do júri
 Fernandes, A.R.A. (Mestrado)
Universidade de Aveiro, Portugal
2014 Aqueous Biphasic Systems Formed by Non-Conventional Phase-Forming Components for the Purification of Lipolytic Enzymes Souza, R.L. (Doutoramento)
Universidade de Tiradentes, Brasil
2014 Novel Process for Lactoferrin Recovery: Ionic Liquid-based Three Phase Partitioning (ILTPP) Guerra, E.A. (Doutoramento)
Universidad de Cantabria, Espanha
2014 Mercaptans Extraction from Jet-Fuel Streams with Ionic Liquids Ferreira, A.R.M. (Doutoramento)
Universidade de Aveiro, Portugal
2014 Caracterización Fisicoquímica y Ecotoxicológica de Disolventes Procedentes de la Biomasa Eraso, L.L. (Doutoramento)
Universidad San Jorge, Espanha
2014 Caracterização de Diferentes Variedades de Arroz – Efeito de Diferentes Métodos de Cozedura
Presidente do júri
 Cardoso, I.N. (Mestrado)
Universidade de Aveiro, Portugal
2014 Caracterização de Variedades de Arroz: Aspectos Nutricionais
Presidente do júri
 Soares, A.R.A. (Mestrado)
Universidade de Aveiro, Portugal
2012 Essays on Ionic Liquid/Activated Carbon Systems and their Application to Pollutants Removal Lemus, J. (Doutoramento)
Universidad Autónoma de Madrid, Espanha
2012 Extraction of added value products from black condensate Mourão, T.M.M. (Mestrado)
Universidade de Aveiro, Portugal
2011 Lipase Production for Extractive Fermentation with Ionic Liquids Ventura, S.P.M. (Doutoramento)
Universidade de Aveiro, Portugal
2010 Aseguramiento de Flujo en Crudos de Petróleo: Estudio de la Precipitación de Parafinas Fuentes, M.D.R. (Doutoramento)
Universidad Rey Juan Carlos, Espanha
2010 Pre-treatment of Lignocellulosic Biomass with Ionic Liquids Oliveira, A.T. (Mestrado)
Universidade de Aveiro, Portugal
2010 CO2/CH4 Separation with Ionic Liquids Ferreira, C.I.F. (Mestrado)
Universidade de Aveiro, Portugal
2010 Development of a Solubility Parameter Scale for Ionic Liquids Batista, M.L.S. (Mestrado)
Universidade de Aveiro, Portugal
2010 Electrospinning of Cellulose from Ionic Liquids Solutions Teles, A.R.R. (Mestrado)
Universidade de Aveiro, Portugal
2009 Extracção de Hemiceluloses com Líquidos Iónicos Ferreira, J.P.S. (Mestrado)
Distinções

Prémio

2023 Award Professor Almiro e Castro
2021 Best Researcher Award by the University of Aveiro
Universidade de Aveiro, Portugal

Outra distinção

2022 Member of the Lisbon Academy of Sciences
Lisbon Academy of Sciences, Portugal
2022 Member of the European Academy of Sciences
2019 “Vicent de Seabra” Medal 2019
2018 Best Poster Award in the Jornadas CICECO 2018.
2018 Recognition by the Royal Society of Chemistry as one of the 100 selected women in Chemistry, a themed collection entitled “Celebrating excellence in research: 100 women of chemistry”
Royal Society of Chemistry, Reino Unido
2018 PurAvTec Business idea awarded at "Born from Knowledge" competition, promoted by the Ministry of Science, Technology and Higher Education, through the National Agency of Innovation (ANI), in the Health field.
2017 Elected member of the Young Scientists Seminar of the Lisbon Academy of Sciences in 2017
2017 Best Poster Award in the III Encontro Nacional de Estudantes de Biotecnologia in 2017
2017 Best Poster Award in the Biopartitioning and Purification (BPP) Conference
2017 Recognition by journal “Green Chemistry” in the “Emerging Investigators” themed issue as amongst the top 14 Rising Stars in the Green Chemistry field in 2017
2016 Best Poster Award
2016 Best Poster Award Honorable Mention
2016 Best Poster Award
2016 Best Poster Award
2016 Best PhD thesis (Jorge F. B. Pereira; co-supervior)
2015 Best Poster Award
2015 Top 20 “Women in Science” in Portugal
2014 ECTP-NETZSCH Young Scientist Award
2014 Advisor of the winner MSc thesis (Sara F. Carvalho) in the Industrial and Technology Category
2013 Principal Investigator of an European Research Council (ERC) Starting Grant
2012 Best Poster Award
2008 Best Poster Award
2006 Best Poster Award
2004 Best Poster Award
2003 Best Chemistry Student in the University of Aveiro in 2002-2003