???global.info.a_carregar???
Célia got her PhD degree in Biomedical Sciences at the Faculty of Medicine, University of Coimbra, in 2010. Her PhD research project clarified the role of inflammatory mediators in retinal microvascular dysfunction in diabetic retinopathy. She spent 2 years at the Penn State Hershey Retina Research Group, Department of Cellular and Molecular Physiology, Penn State University College of Medicine, Hershey, Pennsylvania, USA, to develop complementary studies for her PhD. After that, Célia Aveleira became a postdoctoral researcher at the Center for Neuroscience and Cell Biology, University of Coimbra. Her research was focused on the role of caloric restriction mimetics as therapeutics targets to delay the aging process of normal and premature aging diseases, such as Hutchinson-Gilford progeria syndrome (HGPS). In 2011, Célia Aveleira was granted with a FCT Post-Doctoral fellowship to study the potential role of neuropeptide Y (NPY) as a mimetic of caloric restriction to reduce aging and ameliorate age-related diseases. In 2013 she got a position at CNC, as an Invited Scientist under the project “Aging, Stress and Chronic Diseases: From Mechanisms to Therapeutics”, supported by QREN - Mais Centro: Programa Operacional Regional do Centro. In line with her research, Celia was awarded in April 2015 with an Innovator Research Grant as Principal Investigator from Progeria Research Foundation (USA) to study the therapeutic potential of ghrelin to rescue HGPS premature aging phenotype. In January 2017 Célia was enrolled in the FCT Investigator Programme and started her appointment as Assistant Investigator at CNC. For the past years, Celia has been working within the Aging and Neuroscience fields, particularly focused on aging mechanisms and how the hypothalamus regulates whole-body aging as well as on the potential of neuroendocrine peptides to delay the aging process of normal and age-related diseases. In April 2022 Celia joined the Multidisciplinary Institute of Ageing (MIA-Portugal), University of Coimbra, as an Assistant investigator. Her research has been focused on understanding the mechanisms underlying brain ageing and neurodegenerative diseases. The ultimate goal is to develop novel therapeutic strategies to delay/ameliorate age-related diseases and improve quality of life. Célia A. Aveleira is the author/co-author of 25 scientific articles (7 as 1st and 3 as senior author; 19 published in Q1 journals, 2275 citations, and h-factor 16 (Scopus). She is also co-author of 2 book chapters. As an important component of the dissemination of her research outputs, she participated in several national and international meetings being an author/coauthor of 138 presentations: 60 oral communications (22 as 1st author and 11 as senior author) and 82 poster presentations (29 as 1st author and 13 as senior author). She has participated in 18 research projects (2 as PI and 1 as Co-PI) and has been responsible for student training and supervision: 5 MSc and 4 BSc students as principal supervisor, 4 PhD (ongoing) and 4 MSc students as co-supervisor, and collaborated in the supervision of 2 PhD, 2 MSc, and 7 undergraduate students. Célia A. Aveleira was granted 13 awards/grants. She has participated as a lecturer in several MSc and PhD programs of the University of Coimbra and other Portuguese Universities and in several academic examining committees of MSc and PhD Thesis. She is a Review Editor of Frontiers in Aging and peer-reviewed in several international journals. In addition to her scientific activity, Célia has also participated in several science communication activities, particularly, in Brain Awareness Week, European Researchers Night, and Ciência Viva summer program, as well as other activities related to science dissemination to high school students and teachers. In 2020 Celia become a mother of twins and had a career break due to high-risk pregnancy leave and maternity leave which impacted her scientific productivity.
Ler resumo completo ↓
Identificação

Identificação pessoal

Nome completo
Célia Alexandra Ferreira de Oliveira Aveleira

Nomes de citação

  • Aveleira, Célia
  • Aveleira C
  • Aveleira CA

Identificadores de autor

Ciência ID
651B-75AE-BD02
ORCID iD
0000-0002-2191-0682
Researcher Id
L-1325-2014
Scopus Author Id
16052066600

Endereços de correio eletrónico

  • celia.aveleira@uc.pt (Profissional)
  • celia.aveleira@gmail.com (Pessoal)

Moradas

  • Multidisciplinary institute of Ageing (MIA-Portugal), Universidade de Coimbra, Faculdade de Medicina, Pólo I, 3º andar, 3004-504, Coimbra, Coimbra, Portugal (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências
  • Ciências Médicas e da Saúde - Medicina Clínica - Endocrinologia e Metabolismo
  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia
  • Ciências Médicas e da Saúde - Medicina Básica - Patologia
  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2016/01 - 2016/12
Concluído
 Ghrelin: a new therapeutic strategy to delay aging through hypothalamic control (Pós-doutoramento)
Especialização em Aging; Neurosciences
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 N/A
2015/10 - 2015/12
Concluído
 Ghrelin: a novel therapeutic intervention to rescue the phenotype of Hutchinson-Gilford Progeria Syndrome (Pós-doutoramento)
Especialização em Aging; Neurosciences
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 N/A
2013/10 - 2015/09
Concluído
 Aging, Stress and Chronic Diseases: From Mechanisms to Therapeutics (Pós-doutoramento)
Especialização em Aging; Neurosciences
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 N/A
2011/04 - 2013/09
Concluído
 Neuropeptide Y as a caloric restriction mimetic: a new target for aging? (Pós-doutoramento)
Especialização em Neurosciences
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 N/A
2010/04 - 2011/03
Concluído
 Caloric restriction increases lifespan: role of neuropeptide Y on autophagy (Pós-doutoramento)
Especialização em Neurosciences
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 N/A
2010/04/26 - 2010/05/07
Concluído
 IX Course on Laboratory Animal Science - FELASA C Level (Outros)
Especialização em FELASA C Level
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal

Universiteit Utrecht, Países Baixos
2010/01
Concluído
 Doutoramento em Ciências Biomédicas (PhD in Biomedical Sciences) (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
"The role of inflammatory mediators in retinal microvascular dysfunction: implications for the blood-retinal barrier breakdown in diabetic retinopathy" (TESE/DISSERTAÇÃO)
 Aprovada com Distinção e Louvor/Aproved with Disti
2002/07
Concluído
 Biologia (Licenciatura)
Especialização em Ramo Científico
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"NAT2 polymorphisms and the susceptibility for the microvascular complications of diabetes mellitus type 1" (TESE/DISSERTAÇÃO)
 Sixteen (16/20)
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/04 - Atual Investigador Auxiliar (carreira) (Investigação) Universidade de Coimbra, Portugal
Universidade de Coimbra - Instituto Multidisciplinar do Envelhecimento (MIA-PORTUGAL), Portugal
2017/01/01 - 2021/12/31 Investigador Auxiliar (carreira) (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2017/01/01 - 2021/12/31 Assistant Investigator, under the FCT Investigator Programme Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
CNC.IBILI, Portugal
2016/01/01 - 2016/12/31 Post-Doc fellow - Post-Doc fellowship of Foundation for Science and Technology, Portugal (Ref: SFRH/BPD/111710/2015). Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/10/01 - 2015/12/31 Post-Doc fellow. Research Project: Ghrelin: a novel therapeutic intervention to rescue the phenotype of Hutchinson-Gilford Progeria Syndrome, supported by the Progeria Research Foundation, Boston, USA Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/10/01 - 2015/09/30 Invited Scientist researcher. Project “Aging, Stress and Chronic Diseases: From Mechanisms to Therapeutics” (Project reference: CENTRO-07-ST24-FEDER-002006). Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2011/04/01 - 2013/09/30 Post-Doc fellow - Post-Doctoral fellowship of the Foundation for Science and Technology (FCT), Portugal (Ref: SFRH/BPD/73942/2010). Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2010/04/01 - 2011/03/01 Postdoctoral fellow. Project “Caloric restriction increases lifespan: role of neuropeptide Y on autophagy”, Foundation for Science and Technology (FCT), Portugal Ref: PTDC/SAU-FCF/099082/2008. Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2005/02/01 - 2010/01/31 PhD student. PhD fellowship of the Foundation for Science and Technology (FCT), Portugal (Ref: SFRH/BD/18727/2004). Universidade de Coimbra Faculdade de Medicina, Portugal
Institute of Biomedical Research in Light and Image (IBILI), Portugal
2007/03/01 - 2008/12/01 Visiting PhD student. Department of Cellular and Molecular Physiology, Penn State College of Medicine, Pennsylvania State University, Hershey, Pennsylvania, USA. Universidade de Coimbra Faculdade de Medicina, Portugal
Penn State College of Medicine, Estados Unidos
2003/02/01 - 2005/01/31 Research fellow in the project “Mechanisms of cell degeneration in diabetic retinopathy”, supported by the Foundation for Science and Technology (FCT), Portugal (Ref: POCTI/CBO/38545/01). Universidade de Coimbra Faculdade de Medicina, Portugal
Institute of Biomedical Research in Light and Image (IBILI), Portugal
2001/09/01 - 2002/09/01 Undergraduate training. Research project: “NAT2 polymorphisms and the susceptibility for the microvascular complications of diabetes mellitus type 1”. Universidade de Coimbra Faculdade de Medicina, Portugal
Projetos

Bolsa

Designação Financiadores
2021/01 - 2025/12 Centro de Inovação em Biomedicina e Biotecnologia - Laboratório Associado
168189UID
 Fundação para a Ciência e a Tecnologia
2016/01/01 - 2016/12/31 Ghrelin: a new therapeutic strategy to delay aging through hypothalamic control
SFRH/BPD/111710/2015
Bolseiro de Pós-Doutoramento
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2013/01 - 2014/12 Heatlh Sciences (Institutional strategic project)
PEst-C/SAU/LA0001/2013e2014
Investigador
Fundação para a Ciência e a Tecnologia, Portugal
Concluído
2011/04/01 - 2013/09/30 Neuropeptide Y as a caloric restriction mimetic: a new target for aging?
SFRH/BPD/73942/2010
Bolseiro de Pós-Doutoramento
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
2011/01 - 2012/12 Heatlh Sciences (Institutional strategic project)
PEst-C/SAU/LA0001/2011
Investigador
Fundação para a Ciência e a Tecnologia, Portugal
Concluído
2005/02/01 - 2009/01/31 The role of interleukin-1 beta in blood-retinal barrier breakdown in the early stages of Diabetic Retinopathy
SFRH/BD/18727/2004
Bolseiro de Doutoramento
Universidade de Coimbra Faculdade de Medicina, Portugal

Institute of Biomedical Research in Light and Image (IBILI), Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2020/01 - 2024/12 CIBB (Center for Innovative Biotecnology and Biomedicine) - Institutional Strategic Project
UIDB/04539/2020
Investigador
Fundação para a Ciência e a Tecnologia, Portugal
Em curso
2017/01/01 - 2021/12/31 Ghrelin: a new therapeutic strategy to delay aging through hypothalamic control
IF/00825/2015
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/07/06 - 2021/07/05 Ostructive Sleep Apnea early diagnosis as a new strategy to delay ageing
PTDC/MEC-MCI/29002/2017
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2018/06 - 2021/05 NiNjA - New Neuroendocrine Strategy for healthy Aging (Co-Principal Investigator)
POCI-01-0145-FEDER-030167
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2017/01 - 2020/12 HEALTHY AGING 2020
CENTRO-01-0145-FEDER-000012
Investigador
Universidade de Coimbra, Portugal
 Centro2020 - Programa Operacional Centro 2020 (FEDER/FSE)
Em curso
2016/06/01 - 2019/12/31 Imaging Gene Therapy in the Brain
PTDC/BBB-NAN/0932/2014
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2015/01 - 2018/12 CNC.IBILI - Institutional strategic project
POCI-01-0145-FEDER-007440
Investigador
European Regional Development Fund, Bélgica
Concluído
2015/04 - 2016/12 Ghrelin: a novel therapeutic intervention to rescue the phenotype of Hutchinson-Gilford Progeria Syndrome
PRF2014-53
Investigador responsável
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Progeria Research Foundation
Concluído
2013/10 - 2015/09 Aging, Stress and Chronic Diseases: From Mechanisms to Therapeutics
CENTRO-07-ST24-FEDER-002006
Bolseiro de Cientista Convidado
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 QREN - Mais Centro: Programa Operacional Regional do Centro 2007-2013
Concluído
2010/04/01 - 2013/09/30 Impact of methamphetamine on the blood-brain barrier: unmasking the underlying mechanisms and the role of neuroinflammation
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/98685/PT
Investigador
Universidade de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade do Algarve Faculdade de Ciências e Tecnologia
Concluído
2010/04/01 - 2011/03/31 Caloric restriction increases lifespan: role of neuropeptide Y on autophagy
PTDC/SAU-FCF/099082/2008
Bolseiro de Pós-Doutoramento
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2007/06/01 - 2010/12/31 Regulation of AMPA receptors by hyperglycemia in the retina
PTDC/SAU-NEU/71228/2006
Investigador
Universidade de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2007/05/01 - 2010/11/30 Neuropeptide Y in the retina: Why? What for?
PTDC/SAU-NEU/73119/2006
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2005/01 - 2005/12 Regulation of the expression of the type I IL-1 receptor in the retina
GAI 10/05
Investigador
Universidade de Coimbra Faculdade de Medicina, Portugal

Institute of Biomedical Research in Light and Image (IBILI), Portugal
Faculdade de Medicina, Universidade de Coimbra
Concluído
2002/02/01 - 2005/01/31 Mechanisms of cell degeneration in diabetic retinopathy
POCTI/CBO/38545/2001
Bolseiro de Investigação
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Ferreira-Marques, M (EA15-6C9F-F15E); Cortes, Luisa; Valero, Jorge; Pereira, Dina; Almeida, Luís Pereira de; Cavadas, Cláudia (D413-2E77-4BDE); Aveleira, Célia A (651B-75AE-BD02). Autor correspondente: Aveleira, Célia A (651B-75AE-BD02). "Human Progeria fibroblasts in culture to study new strategies to delay aging". Trabalho apresentado em JRC Summer School on Non-Animal Approaches in Science: The Three R...evolution, 2021.
    Publicado
  2. Leal, Helena; Ferreira-Marques, M (EA15-6C9F-F15E); Aveleira, Célia; Gomes, Pedro; Cavadas, Cláudia (D413-2E77-4BDE). Autor correspondente: Cavadas, Cláudia (D413-2E77-4BDE). "Experimental models to evaluate hypothalamic insulin signaling in metabolic dysfunctions". Trabalho apresentado em JRC Summer School on Non-Animal Approaches in Science: The Three R...evolution, 2021.
    Publicado
  3. Cavadas, Claudia; Ferreira-Marques, Marisa; Carmo-Silva, Sara; Botelho, Mariana; Aveleira, Célia. "Neuropeptide Y stimulates autophagy in hypothalamic neurons.". Trabalho apresentado em 30th ECNP Congress, Paris, 2017.
    Publicado • 10.1016/s0924-977x(17)31002-7
  4. Botelho, Mariana; Aveleira, Célia; Carmo-Silva, Sara; Pascoal, Jorge; Ferreira-Marques, Marisa; Nóbrega, Clévio; Cortes, Luísa; et al. "Neuropeptide Y1 and Y5 receptors activation stimulate autophagic flux in mouse hypothalamic neurons.". Trabalho apresentado em 11th NPY-PYY-PP International Meeting, Leipzig, 2016.
    Publicado • 10.1016/j.npep.2015.11.035
  5. Domingues, Maria do Rosário; Faria, Renata; Simões, Cláudia; Aveleira, Célia; Santana, Magda; Cavadas, Claudia. "Alteration in brain phospholipid profile after chronic stress: a lipidomic study.". Trabalho apresentado em Society for Free Radical Research International 16th Biennial Meeting, Londres, 2012.
    Publicado • 10.1016/j.freeradbiomed.2012.08.380
  6. Felinski, E. A.; Smith, C. D.; Aveleira, Célia; Lin, C. M.; Antonetti, David A.. "Atypical PKC inhibitors block both VEGF and TNF-alpha induced endothelial permeability.". Trabalho apresentado em 69th Annual Meeting of the American Diabetes Association, Nova Oleães, 2009.
    Publicado
  7. Aveleira, Célia; Wolpert, Ellen B.; Ambrósio, António F.; Antonetti, David A.. "TNF signals through NF-kB to induce retinal endothelial cell permeability.". Trabalho apresentado em ARVO Annual Meeting 2009, Fort Lauderdale, 2009.
    Publicado
  8. Ambrósio, António F.; Aveleira, Célia; Wolpert, Ellen B.; Antonetti, David A.. "The action of pro-inflammatory cytokines on retinal endothelial cell barrier permeability: protective effect of corticosteroids.". Trabalho apresentado em European Association for Vision and Eye Research - EVER 2008, Portoroz, 2008.
    Publicado • 10.1111/j.1755-3768.2008.5325.x
  9. Ambrósio, António F.; Leal, Ermelindo C.; Aveleira, Célia; Castilho, Áurea F.; Baptista, Filipa I.. "Müller cells do not influence leukocyte adhesion to retinal endothelial cells.". Trabalho apresentado em ARVO Annual Meeting 2008, Fort Lauderdale, 2008.
    Publicado
  10. Aveleira, Célia; Wolpert, Ellen B.; Ambrósio, António F.; Antonetti, David A.. "Pro-inflammatory cytokines increase retinal endothelial cell permeability: protective effect of dexamethasone.". Trabalho apresentado em ARVO Annual Meeting 2008, 2008.
  11. Leal, Ermelindo C.; Aveleira, Célia; Castilho, Áurea F.; Hosoya, K.-I.; Ambrósio, António F.; Forrester, John V.. "High glucose, oxidative and nitrosative stress increase leukocyte adhesion to retinal endothelial cells in culture.". Trabalho apresentado em ARVO Annual Meeting 2006, Fort Lauderdale, 2006.
    Publicado
  12. Ambrósio, António F.; Castilho, Áurea F.; Aveleira, Célia; Leal, Ermelindo C.; Fernandes, Carolina R.; Meirinhos, Rita I.; Simões, Núria F.; Terasaki, T.; Hosoya, K.-I.. "Protective role of Heme Oxygenase-1 against high glucose and oxidative nitrosative stress in retinal endothelial cells.". Trabalho apresentado em ARVO Annual Meeting 2006, Fort Lauderdale, 2006.
    Publicado
  13. Aveleira, Célia; Simões, Núria F.; Fernandes, Carolina R.; Meirinhos, Rita I.; Leal, Ermelindo C.; Hosoya, K.-I.; Ambrósio, António F.. "Interleukin-1 beta type I receptor (IL-1RI) regulation in retinal endothelial cells.". Trabalho apresentado em ARVO Annual Meeting 2006, Fort Lauderdale, 2006.
    Publicado
  14. Leal, Ermelindo C.; Manivannan, A.; Aveleira, Célia; Serra, Andreia M.; Castilho, Áurea F.; Terasaki, T.; Hosoya, K.-I.; et al. "Leukocyte adhesion and blood retinal barrier (BRB) breakdown in Diabetic Retinopathy (DR): Role of nitric oxide (NO).". Trabalho apresentado em ARVO Annual Meeting 2005, Fort Lauderdale, 2005.
    Publicado
  15. Castilho, Áurea F.; Aveleira, Célia; Leal, Ermelindo C.; Serra, Andreia M.; Fernandes, Carolina R.; Meirinhos, Rita I.; Ambrósio, António F.. "Heme oxigenase-1: a defense against stress conditions in retinal endothelial cells.". Trabalho apresentado em 15th Meeting of European Association for the Study of Diabetes Eye Complications Study Group – Eye Complications Study Group (EASDec), Coimbra, 2005.
    Publicado
  16. Aveleira, Célia; Castilho, Áurea F.; Leal, Ermelindo C.; Serra, Andreia M.; Álvaro, Ana Rita ; Fernandes, Carolina R.; Meirinhos, Rita I.; Ambrósio, António F.. "Interleukin-1 beta synthesis and Interleukin-1 receptor type I expression in retinal cells: effect of high glucose and interleukin-1 beta.". Trabalho apresentado em 15th Meeting of European Association for the Study of Diabetes Eye Complications Study Group – Eye Complications Study Group (EASDec), Coimbra, 2005.
    Publicado
  17. Ambrósio, António F.; Leal, Ermelindo C.; Manivannan, A.; Aveleira, Célia; Serra, Andreia M.; Castilho, Áurea F.; Terasaki, T.; Hosoya, K.-I.; Forrester, John V.. "The involvement of nitric oxide in leukocyte adhesion and blood-retinal barrier breakdown.". Trabalho apresentado em 15th Meeting of European Association for the Study of Diabetes Eye Complications Study Group – Eye Complications Study Group (EASDec), Coimbra, 2005.
    Publicado
  18. Castilho, Áurea F.; Aveleira, Célia; Leal, Ermelindo C.; Serra, Andreia M.; Fernandes, Carolina R.; Meirinhos, Rita I.; Ambrósio, António F.. "Heme oxygenase-1: a defense against oxidative stress in rat retinal endothelial cells.". Trabalho apresentado em 9th Meeting of the Portuguese Society of Neurosciences, Coimbra, 2005.
    Publicado
  19. Aveleira, Célia; Castilho, Áurea F.; Leal, Ermelindo C.; Serra, Andreia M.; Álvaro, Ana Rita ; Fernandes, Carolina R.; Meirinhos, Rita I.; Ambrósio, António F.. "Interleukin-1 receptor type I is regulated by high glucose and interleukin-1 beta in retinal cells.". Trabalho apresentado em 9th Meeting of the Portuguese Society of Neurosciences, Coimbra, 2005.
    Publicado
  20. Ambrósio, António F.; Leal, Ermelindo C.; Manivannan, A.; Cotter, M.; Aveleira, Célia; Serra, Andreia M.; Castilho, Áurea F.; Hosoya, K.-I.; Forrester, John V.. "Inhibition of nitric oxide synthase prevents leukocyte adhesion and blood-retinal barrier breakdown in diabetic retinas.". Trabalho apresentado em 9th Meeting of the Portuguese Society of Neurosciences, Coimbra, 2005.
    Publicado
  21. Ambrósio, António F.; Aveleira, Célia; Leal, Ermelindo C.; Castilho, Áurea F.; Serra, Andreia M.. "Downregulation of interleukin-1 type-I receptor protein expression by hyperglycemia and interleukin-1 beta in retinal endothelial cells.". Trabalho apresentado em Society for Neuroscience 34th Annual Meeting, San Diego, 2004.
    Publicado
  22. Castilho, Áurea F.; Serra, Andreia M.; Leal, Ermelindo C.; Aveleira, Célia; Ambrósio, António F.. "Retinal endothelial cell dysfunction caused by hyperglycemia and oxidative stress.". Trabalho apresentado em EVER 2004 Annual Meeting, Algarve, 2004.
    Publicado
  23. Aveleira, Célia; Leal, Ermelindo C.; Castilho, Áurea F.; Serra, Andreia M.; Ambrósio, António F.. "Heme oxygenase-1 response to diabetes, hyperglycemia and oxidative stress in retinas and endothelial cells.". Trabalho apresentado em EVER 2004 Annual Meeting, Algarve, 2004.
    Publicado
  24. Leal, Ermelindo C.; Aveleira, Célia; Sá, M.; Serra, Andreia M.; Castilho, Áurea F.; Terasaki, T.; Hosoya, K.-I.; Cunha-Vaz, José; Ambrósio, António F.. "Rat retinal endothelial cell dysfunction induced by hyperglycemia and oxidative stress: additive effects?". Trabalho apresentado em ARVO Annual Meeting 2004, Fort Lauderdale, 2004.
    Publicado
  25. Leal, Ermelindo C.; Aveleira, Célia; Serra, Andreia M.; Castilho, Áurea F.; Hosoya, K.-I.; Cotter, M.; Forrester, John V.; Ambrósio, António F.. "Nitric oxide downregulates tight junction proteins and increases blood-retinal barrier permeability.". Trabalho apresentado em Society for Neuroscience 35th Annual Meeting, Washington, 1999.
    Publicado
Artigo em revista
  1. Lucas, V.; Cavadas, C.; Aveleira, C.A.. "Cellular Senescence: From Mechanisms to Current Biomarkers and Senotherapies". Pharmacological Reviews 75 4 (2023): 675-713. http://www.scopus.com/inward/record.url?eid=2-s2.0-85163864527&partnerID=MN8TOARS.
    10.1124/pharmrev.122.000622
  2. Carmo-Silva, S.; Ferreira-Marques, M.; Nóbrega, C.; Botelho, M.; Costa, D.; Aveleira, C.A.; Pulst, S.M.; de Almeida, L.P.; Cavadas, C.. "Ataxin-2 in the hypothalamus at the crossroads between metabolism and clock genes". Journal of Molecular Endocrinology 70 1 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85143645604&partnerID=MN8TOARS.
    10.1530/JME-21-0272
  3. Ferreira-Marques, M.; Carvalho, A.; Franco, A.C.; Leal, A.; Botelho, M.; Carmo-Silva, S.; Águas, R.; et al. "Ghrelin delays premature aging in Hutchinson-Gilford progeria syndrome". Aging Cell 22 12 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85174420928&partnerID=MN8TOARS.
    10.1111/acel.13983
  4. Franco, A.C.; Aveleira, C.; Cavadas, C.. "Skin senescence: mechanisms and impact on whole-body aging". Trends in Molecular Medicine 28 2 (2022): 97-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-85122623473&partnerID=MN8TOARS.
    10.1016/j.molmed.2021.12.003
  5. Ferreira-Marques, Marisa (EA15-6C9F-F15E); Carvalho, A; Cavadas, Cláudia (D413-2E77-4BDE); Aveleira, Célia A (651B-75AE-BD02); Ferreira-Marques, M.; Carvalho, A.; Cavadas, C.; Aveleira, C.A.. "PI3K/AKT/MTOR and ERK1/2/MAPK signaling pathways are involved in autophagy stimulation induced by caloric restriction or caloric restriction mimetics in cortical neurons.". Aging 13 6 (2021): 7872-7882. http://www.scopus.com/inward/record.url?eid=2-s2.0-85103994461&partnerID=MN8TOARS.
    Aceite para publicação • 10.18632/aging.202805
  6. Klionsky D J; Abdel-Aziz A K; ...; Aveleira C; Chun-Kit Tong. "Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)". Autophagy (2021): https://www.tandfonline.com/doi/full/10.1080/15548627.2020.1797280.
    Publicado
  7. Aveleira, Célia A; Ferreira-Marques, Marisa; Cortes, Luísa; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luís; Cavadas, Cláudia. "Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells.". The Journals of Gerontology: Series A (2020): http://dx.doi.org/10.1093/gerona/glz280.
    Publicado • 10.1093/gerona/glz280
  8. Baptista, Filipa I.; Aveleira, Célia A.; Castilho, Áurea F.; Ambrósio, António F.. "Elevated Glucose and Interleukin-1ß Differentially Affect Retinal Microglial Cell Proliferation". Mediators of Inflammation 2017 (2017): 1-11. http://dx.doi.org/10.1155/2017/4316316.
    Publicado • 10.1155/2017/4316316
  9. Ferreira-Marques, Marisa; Aveleira, Célia A.; Carmo-Silva, Sara; Botelho, Mariana; Pereira de Almeida, Luís; Cavadas, Cláudia. "Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation". Aging 8 7 (2016): 1470-1484. http://dx.doi.org/10.18632/aging.100996.
    Publicado • 10.18632/aging.100996
  10. Cavadas, Cláudia; Aveleira, Célia A.; Souza, Gabriela F. P.; Velloso, Lício A.. "The pathophysiology of defective proteostasis in the hypothalamus - from obesity to ageing". Nature Reviews Endocrinology 12 12 (2016): 723-733. http://dx.doi.org/10.1038/nrendo.2016.107.
    Publicado • 10.1038/nrendo.2016.107
  11. Santana, Magda M.; Rosmaninho-Salgado, Joana; Cortez, Vera; Pereira, Frederico C.; Kaster, Manuella P.; Aveleira, Célia A.; Ferreira, Marisa; Álvaro, Ana Rita; Cavadas, Cláudia. "Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress". European Neuropsychopharmacology 25 10 (2015): 1753-1766. http://dx.doi.org/10.1016/j.euroneuro.2015.06.013.
    Publicado • 10.1016/j.euroneuro.2015.06.013
  12. Baptista, Filipa I.; Castilho, Áurea F.; Gaspar, Joana M.; Liberal, Joana T.; Aveleira, Célia A.; Ambrósio, António F.. "Long-term exposure to high glucose increases the content of several exocytotic proteins and of vesicular GABA transporter in cultured retinal neural cells". Neuroscience Letters 602 (2015): 56-61. http://dx.doi.org/10.1016/j.neulet.2015.06.044.
    Publicado • 10.1016/j.neulet.2015.06.044
  13. Aveleira, Célia A; Botelho, Mariana; Cavadas, Cláudia. "NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging?". Autophagy 11 8 (2015): 1431-1433. http://dx.doi.org/10.1080/15548627.2015.1062202.
    10.1080/15548627.2015.1062202
  14. Aveleira, Célia A.; Botelho, Mariana; Carmo-Silva, Sara; Pascoal, Jorge F.; Ferreira-Marques, Marisa; Nóbrega, Clévio; Cortes, Luísa; et al. "Neuropeptide Y stimulates autophagy in hypothalamic neurons". Proceedings of the National Academy of Sciences 112 13 (2015): E1642-E1651. http://dx.doi.org/10.1073/pnas.1416609112.
    Publicado • 10.1073/pnas.1416609112
  15. Faria, R.; Santana, M.M.; Aveleira, C.A.; Simões, C.; Maciel, E.; Melo, T.; Santinha, D.; et al. "Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress". Neuroscience 273 (2014): 1-11. http://dx.doi.org/10.1016/j.neuroscience.2014.04.042.
    Publicado • 10.1016/j.neuroscience.2014.04.042
  16. Sousa-Ferreira, Lígia; Aveleira, Célia; Botelho, Mariana; Álvaro, Ana Rita; Pereira de Almeida, Luís; Cavadas, Cláudia. "Fluoxetine Induces Proliferation and Inhibits Differentiation of Hypothalamic Neuroprogenitor Cells In Vitro". PLoS ONE 9 3 (2014): e88917. http://dx.doi.org/10.1371/journal.pone.0088917.
    Publicado • 10.1371/journal.pone.0088917
  17. Nascimento-Ferreira, Isabel; Nóbrega, Clévio; Vasconcelos-Ferreira, Ana; Onofre, Isabel; Albuquerque, David; Aveleira, Célia; Hirai, Hirokazu; Déglon, Nicole; Pereira de Almeida, Luís. "Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado–Joseph disease". Brain 136 7 (2013): 2173-2188. http://dx.doi.org/10.1093/brain/awt144.
    Publicado • 10.1093/brain/awt144
  18. Santos-Carvalho, Ana; Aveleira, Célia A.; Elvas, Filipe; Ambrósio, António Francisco; Cavadas, Cláudia. "Neuropeptide Y Receptors Y1 and Y2 are Present in Neurons and Glial Cells in Rat Retinal Cells in Culture". Investigative Opthalmology & Visual Science 54 1 (2013): 429. http://dx.doi.org/10.1167/iovs.12-10776.
    Publicado • 10.1167/iovs.12-10776
  19. Castilho, Áurea F.; Aveleira, Célia A.; Leal, Ermelindo C.; Simões, Núria F.; Fernandes, Carolina R.; Meirinhos, Rita I.; Baptista, Filipa I.; Ambrósio, António F.. "Heme Oxygenase-1 Protects Retinal Endothelial Cells against High Glucose- and Oxidative/Nitrosative Stress-Induced Toxicity". PLoS ONE 7 8 (2012): e42428. http://dx.doi.org/10.1371/journal.pone.0042428.
    Publicado • 10.1371/journal.pone.0042428
  20. Sousa-Ferreira, Lígia; Álvaro, Ana Rita; Aveleira, Célia; Santana, Magda; Brandão, Inês; Kügler, Sebastian; Pereira de Almeida, Luís; Cavadas, Cláudia. "Proliferative Hypothalamic Neurospheres Express NPY, AGRP, POMC, CART and Orexin-A and Differentiate to Functional Neurons". PLoS ONE 6 5 (2011): e19745. http://dx.doi.org/10.1371/journal.pone.0019745.
    Publicado • 10.1371/journal.pone.0019745
  21. Aveleira, C. A.; Lin, C.-M.; Abcouwer, S. F.; Ambrosio, A. F.; Antonetti, D. A.. "TNF-  Signals Through PKCz /NF- kB to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability". Diabetes 59 11 (2010): 2872-2882. http://dx.doi.org/10.2337/db09-1606.
    Publicado • 10.2337/db09-1606
  22. Aveleira, Célia; Castilho, Áurea; Baptista, Filipa; Simões, Núria; Fernandes, Carolina; Leal, Ermelindo; Ambrósio, António Francisco. "High glucose and interleukin-1ß downregulate interleukin-1 type I receptor (IL-1RI) in retinal endothelial cells by enhancing its degradation by a lysosome-dependent mechanism". Cytokine 49 3 (2010): 279-286. http://dx.doi.org/10.1016/j.cyto.2009.11.014.
    Publicado • 10.1016/j.cyto.2009.11.014
  23. Leal, Ermelindo C.; Aveleira, Célia A.; Castilho, Áurea F.; Serra, Andreia M.; Baptista, Filipa I.; Hosoya, Ken-Ichi; Forrester, John V.; Ambrósio, António F.. "High glucose and oxidative/nitrosative stress conditions induce apoptosis in retinal endothelial cells by a caspase-independent pathway". Experimental Eye Research 88 5 (2009): 983-991. http://dx.doi.org/10.1016/j.exer.2008.12.010.
    Publicado • 10.1016/j.exer.2008.12.010
  24. Leal, Ermelindo C.; Aveleira, Célia A.; Castilho, Aurea F.; Baptista, Filipa I.; Ambrósio, António F.. "Müller Cells Do Not Influence Leukocyte Adhesion to Retinal Endothelial Cells". Ocular Immunology and Inflammation 16 4 (2008): 173-179. http://dx.doi.org/10.1080/09273940802204535.
    Publicado • 10.1080/09273940802204535
  25. Álvaro, Ana Rita; Rosmaninho-Salgado, Joana; Santiago, Ana Raquel; Martins, João; Aveleira, Célia; Santos, Paulo F.; Pereira, Tiago; et al. "NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells". Neurochemistry International 50 5 (2007): 757-763. http://dx.doi.org/10.1016/j.neuint.2007.01.010.
    Publicado • 10.1016/j.neuint.2007.01.010
Capítulo de livro
  1. Albuquerque, David; Carmo-Silva, Sara; Álvarez-Vaca D; Aveleira C; Nóbrega, Clévio. "Role of Mitochondrial Dysfunction in Human Obesity.". In Handbook of Mitochondrial Dysfunction: a volume in the Evolutionary Cell Biology Series. CRC Press, 2019.
    Publicado
  2. Santana, Magda M.; Cortez, Vera; Aveleira, Célia; Kaster, Manuella; Rosmaninho-Salgado, Joana; Cavadas, Cláudia. "Chronic Unpredictable Stress Induces Catecholaminergic System Changes in Mouse Adrenal Gland". In Catecholamine Research in the 21st Century, editado por Lee E. Eiden, 205. Elsevier, 2014.
    10.1016/b978-0-12-800044-1.00184-7
Poster em conferência
  1. Ferreira-Marques, Marisa; Aveleira, Célia; Xavier, Nissan; Cavadas, Claudia. "Neuroendocrine modulation: a path to youthful pluripotent stem cell-derived phenotypes from progeria". Trabalho apresentado em 3rd RESETageing Conference, 2023.
  2. Aveleira, Célia; Gaspar, Rita; Thibaud Martial; Raimundo, Nuno; Milosevic, Ira. "Loss of dynamin triggers cell senescence, nuclear envelope abnormalities and accumulation of DNA damage". Trabalho apresentado em 3rd RESETageing Conference, 2023.
  3. Ferreira-Marques, Marisa; André Carvalho; Ana Catarina Franco; Ana Leal; Botelho, Mariana; Carmo-Silva, Sara; Águas, Rodolfo; et al. Autor correspondente: Aveleira, Célia. "Ghrelin delays premature and accelerated aging phenotype in progeria experimental models". Trabalho apresentado em Pharma PhD Day – Annual meeting of PhD students in Pharmaceutical Sciences, 2023.
  4. Ferreira-Marques, Marisa; André Carvalho; Botelho, Mariana; Carmo-Silva, Sara; Cavadas, Claudia; Aveleira, Célia. Autor correspondente: Aveleira, Célia. "Caloric restriction, and caloric restriction mimetics: unveiling the signaling pathways underlying autophagy induction in primary rodent brain cortical neurons". Trabalho apresentado em EMBO Workshop Autophagy in brain health and disease, 2022.
  5. Ferreira-Marques, Marisa; André Carvalho; Ana Catarina Franco; Botelho, Mariana; Carmo-Silva, Sara; Águas, Rodolfo; Lucas, Vasco; et al. Autor correspondente: Aveleira, Célia. "Targeting the neuroendocrine system prolongs survival in a mouse model of human aging". Trabalho apresentado em 1st MIA Ageing Spring School & Symposium, 2022.
  6. Real, Ana Carolina; Ferreira-Marques, M (EA15-6C9F-F15E); Cavadas, Cláudia (D413-2E77-4BDE); Aveleira, Célia A (651B-75AE-BD02). Autor correspondente: Aveleira, Célia A (651B-75AE-BD02). "Innovative therapeutical approach to slow down aging in Hutchinson-Gilford Progeria Syndrome". Trabalho apresentado em Innovate Competition | iMed Lisbon 2021, 2021.
  7. Gomes, Marcos; Pereira, Marta; Laranjo, Mariana; Reis, Tiago; Cardoso, Ana Maria; Ferreira, Pedro; Ferreira-Marques, M (EA15-6C9F-F15E); et al. "GRASP2 (dys)function in metabolismo and obesity". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience – SPN2021, 2021.
  8. Ferreira-Marques, M (EA15-6C9F-F15E); Carvalho, André; Arjona, Maria; Oliveira, Inês; Aveleira, Célia; Cavadas, Cl. "Human accelerated aging syndrome: looking at hypothalamic dysfunction for disease onset and progression". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience – SPN2021, 2021.
  9. Aveleira, Célia; Ferreira-Marques, M (EA15-6C9F-F15E); Vinhas, Ana Catarina; Carvalho, André; Nóbrega, Clévio David Rodrigues ; Cavadas, Claudia. "The effect of a novel caloric restriction mimetic on neurogenesis regulation in the hypothalamus". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience – SPN2021, 2021.
  10. Ferreira-Marques, Marisa; Carvalho, André; Botelho, Mariana; Carmo-Silva, Sara; Aveleira, Célia A (651B-75AE-BD02); Cavadas, Cláudia (D413-2E77-4BDE). "Caloric Restriction, and Caloric Restriction Mimetics Induce Autophagy In Cortical Neurons Through PI3K/AKT And ERK1/2-MAPK Signaling Pathways". Trabalho apresentado em Virtual Keystone eSymposia, Autophagy: Mechanisms and Disease, 2020.
  11. Ferreira-Marques, Marisa; Carvalho, André; Franco, Ana Catarina da Silva; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia. "Targeting the neuroendocrine system to delay aging phenotype in Progeria.". Trabalho apresentado em Centre of Innovative Biomedicine and Biotechnology (CIBB) Annual Meeting, University of Coimbra, Coimbra, Portugal., 2019.
  12. Franco, Ana Catarina da Silva; Ferreira-Marques, Marisa; Carvalho, André; Carmo-Silva, Sara; Botelho, Mariana; Claudia Cavadas; Aveleira, Célia. "Neuroendocrine peptide as a novel therapeutic strategy to delay skin aging.". Trabalho apresentado em Centre of Innovative Biomedicine and Biotechnology (CIBB) Annual Meeting, University of Coimbra, Coimbra, Portugal., 2019.
  13. Franco, Ana Catarina da Silva; Ferreira-Marques, Marisa; Carvalho, André; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia A (651B-75AE-BD02). "A neuroendocrine strategy to slow down the clock on skin aging.". Trabalho apresentado em BEB day 2019, University of Coimbra, Coimbra, Portugal, 2019.
  14. Ferreira-Marques, Marisa; Carvalho, André; Franco, Ana Catarina da Silva; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia. "Neuroendocrine peptide as a novel strategy to delay aging in HGPS.". Trabalho apresentado em 1st Annual Meeting in Pharmaceutical Sciences, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal., 2019.
  15. Franco, Ana Catarina da Silva; Ferreira-Marques, Marisa; Carvalho, André; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia. "Neuroendocrine peptide as a novel strategy to delay skin aging.". Trabalho apresentado em 1st Annual Meeting in Pharmaceutical Sciences, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal., 2019.
  16. Aveleira, Célia; Ferreira-Marques, Marisa; Cortes, Luísa; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Neuropeptide Y enhances progerin clearance and delays cellular senescence in human Hutchinson-Gilford Progeria Syndrome cells.". Trabalho apresentado em 3rd Molecular Biology of Ageing Meeting, European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen, Groningen, The Netherlands., 2019.
  17. Ferreira-Marques, Marisa; Carvalho, André; Franco, Ana Catarina da Silva; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia. "A new neuroendocrine strategy to delay aging in HGPS.". Trabalho apresentado em 3rd Molecular Biology of Ageing Meeting, European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen, Groningen, The Netherlands., 2019.
  18. Ferreira-Marques, Marisa; Carvalho, André; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia. "Hutchinson-Gilford Progeria Syndrome (HGPS): exploring a neuroendocrine strategy to delay aging.". Trabalho apresentado em Ageing: models, mechanisms and therapies Conference, Faculty of Medicine, University of Coimbra, Coimbra, Portugal., 2019.
  19. Aveleira, Célia; Ferreira-Marques, Marisa; Cortes, Luísa; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Neuropeptide Y ameliorates the aging phenotype of Hutchinson-Gilford Progeria Syndrome cells.". Trabalho apresentado em Ageing: models, mechanisms and therapies Conference, Faculty of Medicine, University of Coimbra, Coimbra, Portugal., 2019.
  20. Franco, Ana Catarina da Silva; Ferreira-Marques, Marisa; Carvalho, André; Carmo-Silva, Sara; Botelho, Mariana; Cavadas, Claudia; Aveleira, Célia. "Ghrelin as a potential therapeutic strategy to delay skin aging and hair loss in Hutchinson-Gilford Progeria Syndrome.". Trabalho apresentado em Ageing: models, mechanisms and therapies Conference, Faculty of Medicine, University of Coimbra, Coimbra, Portugal., 2019.
  21. Ferreira, Inês João Dinis; Ferreira-Marques, Marisa; Carvalho, André; Carmo-Silva, Sara; Botelho, Mariana; Aveleira, Célia; Cavadas, Claudia. "Gut alterations in a mouse model of Progeria.". Trabalho apresentado em Ageing: models, mechanisms and therapies Conference, Faculty of Medicine, University of Coimbra, Coimbra, Portugal., 2019.
  22. Aveleira, Célia; Botelho, Mariana; Cortes, Luísa; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Neuropeptide Y rescues the senescent phenotype of human Hutchinson-Gilford Progeria Syndrome cells.". Trabalho apresentado em Cell Symposia – Aging and Metabolism, Sitges, Spain., 2016.
  23. Carmo-Silva, Sara; Nóbrega, Clévio; Ferreira-Marques, Marisa; Botelho, Mariana; Aveleira, Célia; Pulst, Stefan; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Hypothalamic ataxin-2: a new player in central regulation of regulation of energy balance.". Trabalho apresentado em EMBO Workshop – Neural control of metabolism and eating behavior, Cascais, Portugal., 2016.
  24. Aveleira, Célia; Cortes, Luísa; Ferreira-Marques, Marisa; Leal, Ana; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Ghrelin enhances progerin clearance and rescues the senescent phenotype of human Hutchinson-Gilford Progeria Syndrome cells.". Trabalho apresentado em 8th Progeria Research Foundation International Scientific Workshop – Across the Table, Around the Globe, Cambridge, MA, USA., 2016.
  25. Aveleira, Célia; Cortes, Luísa; Pereira, Joana; Leal, Ana; Pereira, Dina; Valero, Jorge; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Neuropeptide Y rescues the senescent phenotype of human Hutchinson-Gilford Progeria Syndrome cells.". Trabalho apresentado em XIII CNC Annual Meeting, Coimbra, Portugal., 2015.
  26. Carmo-Silva, Sara; Nóbrega, Clévio; Ferreira-Marques, Marisa; Botelho, Mariana; Aveleira, Célia; Álvaro, Ana Rita ; Pulst, Stefan; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Ataxin-2 in the hypothalamus: a novel regulator of energy balance and metabolism.". Trabalho apresentado em XIII CNC Annual Meeting, Coimbra, Portugal., 2015.
  27. Botelho, Mariana; Aveleira, Célia; Carmo-Silva, Sara; Pascoal, Jorge; Ferreira-Marques, Marisa; Nóbrega, Clévio; Cortes, Luísa; et al. "Neuropeptide Y1 and Y5 receptors activation stimulate autophagic flux in mouse hypothalamic neurons.". Trabalho apresentado em 11th NPY-PYY-PP International Meeting, Leipzig, Germany., 2015.
  28. Botelho, Mariana; Aveleira, Célia; Carmo-Silva, Sara; Pascoal, Jorge; Ferreira-Marques, Marisa; Nóbrega, Clévio; Cortes, Luísa; et al. "Autophagy in the hypothalamus: the role of Neuropeptide Y.". Trabalho apresentado em 9th IBRO World Congress on Neuroscience, Rio de Janeiro, Brazil., 2015.
  29. Carmo-Silva, Sara; Nóbrega, Clévio; Ferreira-Marques, Marisa; Botelho, Mariana; Álvaro, Ana Rita ; Aveleira, Célia; Pulst, Stefan; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Impact of hypothalamic ataxin-2 on energy balance and metabolic profile.". Trabalho apresentado em 9th IBRO World Congress on Neuroscience, Rio de Janeiro, Brazil., 2015.
  30. Aveleira, Célia; Cortes, Luísa; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Neuropeptide Y enhances progerin clearance and rescues the senescent phenotype of human Hutchinson-Gilford Progeria Syndrome fibroblasts.". Trabalho apresentado em The Translational Science of Aging: From Functional Pathways to Interventions Gordon Research Conference on Biology of Aging, Sunday River, Newry, USA., 2015.
  31. Aveleira, Célia; Carmo-Silva, Sara; Botelho, Mariana; Ferreira-Marques, Marisa; Nóbrega, Clévio; López-Ótin, Carlos; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Neuropeptide Y rescues the aging phenotype of a mouse model of human premature aging.". Trabalho apresentado em The Translational Science of Aging: From Functional Pathways to Interventions Gordon Research Conference on Biology of Aging, Sunday River, Newry, USA., 2015.
  32. Carmo-Silva, Sara; Nóbrega, Clévio; Botelho, Mariana; Ferreira-Marques, Marisa; Aveleira, Célia; Pulst, Stefan; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Hypothalamic ataxin-2 regulates energy balance and metabolism.". Trabalho apresentado em Neural Control of Metabolic Physiology and Diseases Keystone Symposia on Molecular and Cellular Biology, Snowbird, Utah, USA., 2015.
  33. Aveleira, Célia; Carmo-Silva, Sara; Botelho, Mariana; Ferreira-Marques, Marisa; Nóbrega, Clévio; López-Otín, Carlos; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Neuropeptide Y rescues the aging phenotype of a mouse model of human premature aging.". Trabalho apresentado em XII CNC Annual Meeting, Coimbra, Portugal, 2015.
  34. Álvaro, Ana Rita ; Aveleira, Célia; Martins, Helena; Sousa-Ferreira, Lígia; Botelho, Mariana; Carmo-Silva, Sara; Cavadas, Claudia. "A differential effect of neuropeptide y and caloric restriction on hypothalamus neurogenesis.". Trabalho apresentado em XII CNC Annual Meeting, Coimbra, Portugal, 2014.
  35. Botelho, Mariana; Aveleira, Célia; Pascoal, Jorge; Carmo-Silva, Sara; Nóbrega, Clévio; Cortes, Luísa; Valero, Jorge; et al. "Neuropeptide Y stimulates autophagy in hypothalamic neurons.". Trabalho apresentado em FENS Forum 2014, Milan, Italy, 2014.
  36. Ambrósio, António F.; Baptista, Filipa I.; Aveleira, Célia; Castilho, Áurea F.; Fernandes, Carolina; Simões, Núria. "Effects of high glucose and interleukin-1ß in the different retinal neural cells in culture.". Trabalho apresentado em European Retina Meeting 2013, Alicante, Spain, 2013.
  37. Aveleira, Célia; Botelho, Mariana; Pascoal, Jorge; Carmo-Silva, Sara; Nóbrega, Clévio; Sousa-Ferreira, Lígia; Álvaro, Ana Rita ; et al. "Neuropeptide Y, a caloric restriction mimetic, induces autophagy in hypothalamic neurons.". Trabalho apresentado em EMBO Young Scientists’ Forum, Lisbon, Portugal, 2013.
  38. Aveleira, Célia; Botelho, Mariana; Carmo-Silva, Sara; Sousa-Ferreira, Lígia; Ferreira-Marques, Marisa; Nóbrega, Clévio; López-Otín, Carlos; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Neuropeptide Y ameliorates the phenotype of a mouse model of human premature aging.". Trabalho apresentado em 7th Progeria Research Foundation International Workshop – Hand in Hand: Basic and Clinical Science Working Together Toward the Cure, Bethesda, MD, USA, 2013.
  39. Ambrósio, António F.; Baptista, Filipa I.; Aveleira, Célia; Castilho, Áurea F.; Fernandes, Carolina; Simões, Núria. "Cell-specific effects of high glucose and interleukin-1ß in retinal neural cell cultures.". Trabalho apresentado em Annual meeting of the Portuguese Society of Diabetology, Tomar, Portugal,, 2013.
  40. Botelho, Mariana; Aveleira, Célia; Pascoal, Jorge; Carmo-Silva, Sara; Sousa-Ferreira, Lígia; Nóbrega, Clévio; Álvaro, Ana Rita ; et al. "Neuropeptide Y, an autophagy inducer in hypothalamic neurons.". Trabalho apresentado em X CNC Annual Meeting, Cantanhede, Portugal,, 2012.
  41. Botelho, Mariana; Aveleira, Célia; Sousa-Ferreira, Lígia; Jorge, Pascoal; Nóbrega, Clévio; Álvaro, Ana Rita ; Pereira de Almeida, Luis Fernando Morgado; Cavadas, Claudia. "Role of NPY on autophagy in hypothalamus: a caloric restriction mimetic?". Trabalho apresentado em 10th International NPY-PYY-PP Meeting, Montreal, Canada, 2012.
  42. Baptista, Filipa I.; Aveleira, Célia; Castilho, Áurea F.; Fernandes, Carolina; Ambrósio, António F.. "Interleukin-1 beta affects the expression of IL-1RI and induces proliferation of glial cells in retinal cell cultures.". Trabalho apresentado em III Annual Meeting of IBILI, Coimbra, Portugal, 2011.
  43. Baptista, Filipa I.; Aveleira, Célia; Castilho, Áurea F.; Fernandes, Carolina; Ambrósio, António F.. "Interleukin-1 beta affects the expression of IL-1RI and induces proliferation of glial cells in retinal cell cultures.". Trabalho apresentado em 1st PF2MUC Symposium, Coimbra, Portugal, 2011.
  44. Baptista, Filipa I.; Castilho, Áurea F.; Gaspar, Joana M.; Liberal, Joana; Aveleira, Célia; Ambrósio, António F.. "Chronic high glucose does not affect the content and distribution of several exocytotic and vesicular proteins in primary retinal cell cultures.". Trabalho apresentado em 8th IBRO world Congress of Neuroscience, Florence, Italy, 2011.
  45. Ambrósio, António F.; Aveleira, Célia; Baptista, Filipa I.; Castilho, Áurea F.; Fernandes, Carolina. "Interleukin-1 beta affects the expression of IL-1RI and induces proliferation of glial cells in retinal cell cultures.". Trabalho apresentado em 36th FEBS Congress, Torino, Italy, 2011.
  46. Ambrósio, António F.; Baptista, Filipa I.; Castilho, Áurea F.; Gaspar, Joana M.; Liberal, Joana; Aveleira, Célia. "Chronic high glucose does not induce changes in the content and distribution of exocytotic and vesicular proteins in retinal cells.". Trabalho apresentado em XII Meeting of the Portuguese Society for Neuroscience, Lisbon, Portugal, 2011.
  47. Aveleira, Célia; Ambrósio, António F.; Wolpert, Ellen B.; Antonetti, David A.. "Dexamethasone prevents retinal endothelial cell barrier breakdown induced by pro-inflammatory cytokines.". Trabalho apresentado em 11th International Symposium on Signal Transduction in the Blood-Brain Barriers”, Amsterdam, Netherlands, 2008.
  48. Aveleira, Célia; Wolpert, Ellen B.; Ambrósio, António F.; Antonetti, David A.. "Comparative Study of the Effect of IL-1 ß, TNF-a and MCP-1 on Retinal Endothelial Cell Permeability". Trabalho apresentado em ARVO Summer Eye Research Conference – Preventing Vision Loss in Diabetic Retinopathy, Providence/Warwick, Rhode Island, USA, 2007.
  49. Leal, Ermelindo C.; Aveleira, Célia; Serra, Andreia M.; Castilho, Áurea F.; Forrester, John V.; Ambrósio, António F.. "Apoptosis inducing factor (AIF) pathway is involved in high glucose and oxidative stress-induced apoptosis in retinal endothelial cells.". Trabalho apresentado em XV National Congress of Biochemistry, Aveiro, Portugal,, 2006.
  50. Aveleira, Célia; Castilho, Áurea F.; Simões, Núria F.; Fernandes, Carolina R.; Leal, Ermelindo C.; Ambrósio, António F.. "Interleukin-1 type I receptor downregulation induced by high glucose and interleukin-1 beta in retinal endothelial cells.". Trabalho apresentado em XV National Congress of Biochemistry, Aveiro, Portugal, 2006.
  51. Leal, Ermelindo C.; Aveleira, Célia; Castilho, Áurea F.; Serra, Andreia M.. "High glucose, nitric oxide and H2O2 induce apoptosis in retinal endothelial cells through the apoptosis inducing factor (AIF) pathway.". Trabalho apresentado em V Congresso de Investigação em Medicina, Pedagogia e Ciência, Coimbra, Portugal, 2006.
  52. Castilho, Áurea F.; Aveleira, Célia; Leal, Ermelindo C.; Fernandes, Carolina R.; Meirinhos, Rita I.; Simões, Núria F.; Ambrósio, António F.. "Heme Oxygenase-1 protects retinal endothelial cells against high glucose and oxidative-nitrosative stress.". Trabalho apresentado em V Congresso de Investigação em Medicina, Pedagogia e Ciência, Coimbra, Portugal, 2006.
  53. Aveleira, Célia; Castilho, Áurea F.; Simões, Núria F.; Fernandes, Carolina R.; Leal, Ermelindo C.; Ambrósio, António F.. "High glucose and IL-1beta downregulate interleukin-1 type I receptor in retinal endothelial cells.". Trabalho apresentado em V Congresso de Investigação em Medicina, Pedagogia e Ciência, Coimbra, Portugal, 2006.
  54. Leal, Ermelindo C.; Aveleira, Célia; Serra, Andreia M.; Castilho, Áurea F.; Forrester, John V.; Ambrósio, António F.. "High glucose and oxidative stress induce apoptosis in rat retinal endothelial cells through the Apoptosis Inducing Factor (AIF) pathway.". Trabalho apresentado em International Free Radical Summer School 2006: Biomarkers of oxidative stress and responses, Spetses, Greece, 2006.
  55. Figueiredo, A.; Dias, N.; Aveleira, Célia; Fernandes, Carolina R.; Meirinhos, Rita I.; Ambrósio, António F.. "Avaliação da inserção do módulo de cuidados paliativos na grade curricular formal de alunos de medicina da Faculdade de Ciências Médicas da UNICAMP". Trabalho apresentado em Dia da Faculdade de Medicina da Universidade de Coimbra – Mostra Científica do Gabinete de Apoio à Investigação, Coimbra, Portugal,, 2005.
  56. Leal, Ermelindo C.; Manivannan, A.; Aveleira, Célia; Serra, Andreia M.; Castilho, Áurea F.; Terasaki, T.; Hosoya, K.; et al. "Leukocyte Adhesion and Blood-retinal Barrier (BRB) Breakdown in Diabetic retinopathy (DR): Role of Nitric Oxide (NO).". Trabalho apresentado em III Encontro Anual do Centro de Neurociências e Biologia Celular de Coimbra, Coimbra Portugal, 2005.
  57. Aveleira, Célia; Castilho, Áurea F.; Leal, Ermelindo C.; Álvaro, Ana Rita ; Fernandes, Carolina R.; Meirinhos, Rita I.; Ambrósio, António F.. "Interleukin-1 type I receptor regulation by high glucose and interleukin-1 beta in retinal cells.". Trabalho apresentado em FENS/Blacwell Summer School - Neuro-glia interaction in aging and disease, Ofir, Esposende, Portugal, 2005.
  58. Serra, Andreia M.; Castilho, Áurea F.; Aveleira, Célia; Leal, Ermelindo C.; Ambrósio, António F.. "Retinal endothelial cell dysfunction caused by hyperglycemia and oxidative stress.". Trabalho apresentado em IV Congresso de Investigação em Medicina-Pedagogia e Ciência, Coimbra, Portugal, 2004.
  59. Aveleira C. "Hyperglycemia and oxidative stress cause retinal endothelial cell dysfunction.". Trabalho apresentado em 1st Neuroscience Symposium - International Institute for Neuroscience of Natal, Natal, Brazil, 2004.
  60. Leal, Ermelindo C.; Aveleira, Célia; Sá, M.; Ambrósio, António F.; Cunha-Vaz, José. "Endothelial cell dysfunction caused by hyperglycemia, nitric oxide and H2O2.". Trabalho apresentado em 6th Portuguese Congress on Free Radicals in Chemistry, Biology and Medicine / 1st Luso-Spanish Congress on Free Radicals, Coimbra, Portugal, 2003.
Tese / Dissertação
  1. Aveleira, Célia Alexandra Ferreira de Oliveira. "The role of inflammatory mediators in retinal microvascular dysfunction: implications for the blood-retinal barrier breakdown in diabetic retinopathy". Doutoramento, Universidade de Coimbra Faculdade de Medicina, 2010. http://hdl.handle.net/10316/12268.

Outros

Outra produção
  1. Nuclear aging in polyglutamine-induced neurodegeneration. 2023. Pereira, D.; Cunha-Santos, J.; Vasconcelos-Ferreira, A.; Duarte-Neves, J.; Onofre, I.; Carmona, V.; Aveleira, C.A.; et al. http://www.scopus.com/inward/record.url?eid=2-s2.0-85165916137&partnerID=MN8TOARS.
    10.1101/2023.06.09.544056
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2024/02/09 Neuropeptide Y mitigates the aging phenotype of progeria mesenchymal stem cells: potential implications for therapeutic interventions LIV Meeting of the Portuguese Society of Pharmacology
NOVA Medical School, Faculdade de Ciências Médicas-Universidade NOVA de Lisboa (Lisboa, Portugal)
2023/08/25 Creating a spatial map of cellular senescence in human skin aging 13th Annual Alliance for Healthy Aging Conference,
(Copenhagen, Dinamarca)
2022/12/06 Ghrelin enhances progerin clearance and promotes healthspan in a progeria mouse model Ageing Without Borders
University of Algarve (Faro)
2022/04/04 Targeting the neuroendocrine system prolongs survival in a mouse model of human aging 1st MIA Ageing Spring School & Symposium
Multidisciplinary Institute for Ageing (MIA-Portugal) University of Coimbra (Coimbra, Portugal)
2022 Innovative therapeutical strategy to slow down aging in Hutchinson-Gilford progeria syndrome LII Meeting of the Portuguese Society of Pharmacology
2022 Boosting hypothalamic neurogenesis: toward a novel caloric restriction mimetic LII Meeting of the Portuguese Society of Pharmacology
2021 A neuroendocrine peptide as a novel strategy to delay aging in Hutchinson-Gilford Progeria Syndrome Aging – Unveiling the mysteries of time
2021 A neuroendcrine peptide as a skin anti-ageing strategy LI Meeting of the Portuguese Society of Pharmacology
2021 Hypothalamic Neuropeptide Y (NPY) ameliorates the aging phenotype of a mouse model of human aging LI Meeting of the Portuguese Society of Pharmacology
2020/02 Targeting the neuroendocrine system to slow down skin aging L Meeting of the Portuguese Society of Pharmacology
(Coimbra, Portugal)
2020/02 Development of in vitro approaches to evaluate hypothalamic insulin signaling in metabolic dysfunctions L Meeting of the Portuguese Society of Pharmacology
(Coimbra, Portugal)
2020/02 Overexpression of a specific rna-binding protein ameliorates several abnormalities in cellular models of progeria L Meeting of the Portuguese Society of Pharmacology
(Coimbra, Portugal)
2019/05/17 Progeria: pathophysiology and potential therapies Dr. Lopes Dias School of Health (ESALD) Seminars
Polytechnic Institute of Castelo Branco (Castelo Branco, Portugal)
2019/04/01 How to monitor autophagy in biological systems? Mechanobiology of Migrating Cells: From Basic Science to the Clinic Workshop, COST Action CA15214 (EuroCellNet)
University of Coimbra (Coimbra, Portugal)
2019/04 Autophagy and Aging Mechanobiology of Migrating Cells: From Basic Science to the Clinic Workshop, COST Action CA15214 (EuroCellNet)
University of Coimbra (Coimbra, Portugal)
2019/02 A neuroendocrine strategy to delay aging of Hutchinson-Gilford Progeria Syndrome XLIX Meeting of the Portuguese Society of Pharmacology
(Porto, Portugal)
2018/06/13 Ghrelin delays aging in a mouse model of human accelerated aging syndrome iCBR – Coimbra Institute for Clinical and Biomedical Research Seminars
University of Coimbra, Faculty of Medicine (Coimbra, Portugal)
2018/02 Ghrelin administration as a novel strategy to delay aging in Hutchinson-Gilford Progeria Syndrome XLVIII Meeting of the Portuguese Society of Pharmacology
(Lisbon, Portugal)
2018/02 Caloric restriction activates autophagy in mouse cerebral cortex XLVIII Meeting of the Portuguese Society of Pharmacology
(Lisbon, Portugal)
2017/09 Neuropeptide Y stimulates autophagy in hypothalamic neurons 30th ECNP Congress
(Paris, França)
2017/02 Ghrelin ameliorates the senescent phenotype of human Hutchinson-Gilford Progeria Syndrome cells XLVII Meeting of the Portuguese Society of Pharmacology
(Coimbra, Portugal)
2017/02 Caloric restriction stimulates autophagy in rat cortical neurons through ghrelin receptor activation XLVII Meeting of the Portuguese Society of Pharmacology
(Coimbra, Portugal)
2017/02 Autophagy is stimulated by NPY Y1 and Y5 receptors activation in hypothalamic neurons XLVII Meeting of the Portuguese Society of Pharmacology
(Coimbra, Portugal)
2017/02 Hypothalamic ataxin-2 modulates body weight and insulin sensitivity XLVII Meeting of the Portuguese Society of Pharmacology
(Coimbra, Portugal)
2016/05 NPY reverts HGPS phenotype 8th Progeria Research Foundation International Scientific Workshop – Across the Table, Around the Globe
(Boston, Estados Unidos)
2016/02 Neuropeptide Y rescues the aging phenotype of Human Hutchinson-Gilford Progeria Syndrome cells XLVI Meeting of the Portuguese Society of Pharmacology
(Porto, Portugal)
2016/02 Hypothalamic ataxin-2 contributes to energy balance regulation and metabolism XLVI Meeting of the Portuguese Society of Pharmacology
(Porto, Portugal)
2015/08 Neuropeptide Y1 and Y5 receptors activation stimulate autophagic flux in mouse hypothalamic neurons 11th NPY-PYY-PP International Meeting
(Leipzig, Alemanha)
2014/12 Autophagic flux is stimulated by NPY in hypothalamic neurons and is relevant to synaptic plasticity of POMC hypothalamic neurons XII CNC Annual Meeting
(Coimbra, Portugal)
2014/02 Hypothalamic Neuropeptide Y ameliorates the phenotype of a mouse model of human premature aging XLIII Meeting of the Portuguese Society of Pharmacology
(Coimbra, Portugal)
2014/02 Caloric restriction and Neuropeptide Y induce autophagy in rat cortical neurons XLIII Meeting of the Portuguese Society of Pharmacology
(Coimbra, Portugal)
2014/02 Neuropeptide Y induces autophagy in hypothalamic neurons, independently of MTOR inhibition XLIII Meeting of the Portuguese Society of Pharmacology
(Coimbra, Portugal)
2014/02 Role of chromaffin progenitor cells on adrenal medulla response to stress XLIII Meeting of the Portuguese Society of Pharmacology
(Coimbra, Portugal)
2013/03 Autophagy and neurodegeneration: when the housekeeper takes off! Cellular and Molecular Biology II, Biochemistry II and Neurosciences Integrated Seminars” of the Integrated Master in Medicine, Faculty of Medicine, University of Coimbra
(Coimbra, Portugal)
2013/02 Neuropeptide Y, a caloric restriction mimetic, promotes autophagy in hypothalamic neurons XLIII Meeting of the Portuguese Society of Pharmacology
(Porto, Portugal)
2013/02 Blood-retinal barrier Brain and ocular diseases: How to overcome the barriers? From basic science to imaging approaches”, Doctoral Programme in Health Sciences advanced course, Faculty of Medicine, University of Coimbra
(Coimbra, Portugal)
2013/02 The putative application of neuroprotective strategies with NPY and replacement therapy with induced pluripotent stem cells in retinal diseases XLIII Meeting of the Portuguese Society of Pharmacology
(Porto, Portugal)
2013/02 Chronic unpredictable stress, as a model of depression, induces changes in mouse adrenal gland XLIII Meeting of the Portuguese Society of Pharmacology
(Porto, Portugal)
2012/12 Neuropeptide Y as a caloric restriction mimetic: a new target for aging? “Neuroendocrinology, Aging and Obesity”, Doctoral Program in Experimental Biology and Biomedicine advanced course, Centre for Neuroscience and Cell Biology, University of Coimbra
(Coimbra, Portugal)
2012/02 Neuropeptide Y as a caloric restriction mimetic XLII Meeting of the Portuguese Society of Pharmacology
(Lisboa, Portugal)
2012/02 The role of Neuropeptide Y on autophagy in hypothalamus XLII Meeting of the Portuguese Society of Pharmacology
(Lisbon, Portugal)
2012/02 Fluoxetine promotes the proliferation of hypothalamic neuroprogenitor cells and modifies the expression of neuropeptides that regulate appetite XLII Meeting of the Portuguese Society of Pharmacology
(Lisboa, Portugal)
2011/09 Blood-brain barriers “Introduction to Neurosciences”, Doctoral Programme in Experimental Biology and Biomedicine advanced course, Centre for Neuroscience and Cell Biology, University of Coimbra
(Coimbra, Portugal)
2011/05 PKCz at the crossroad of TNF-a and VEGF signaling pathways: a novel therapeutic strategy to prevent retinal vascular permeability Symposium “Barrier systems in health and disease”, Faculty of Pharmacy, University of Lisbon
(Lisbon, Portugal)
2011/04 Hypothalamic progenitor cells differentiate into functional neurons XLI Meeting of the Portuguese Society of Pharmacology
(Coimbra, Portugal)
2011/04 Fluoxetine promotes hypothalamic progenitor cells proliferation by increasing BDNF and NPY expression 6th Internation Meeting of the Portuguese Society for Stem Cells and Cell Therapies
(Cantanhede, Portugal)
2011/02 Hypothalamic neurospheres: what for? “Adult stem cells - from basic biology to cell replacement therapies”, Doctoral Programme in Experimental Biology and Biomedicine advanced course, Centre for Neuroscience and Cell Biology, University of Coimbra
(Coimbra, Portugal)
2010/12 Modulation of Neuropeptide Y in the adult hypothalamus and hypothalamic neurospheres – Role on feeding behavior VIII CNC Meeting
(Coimbra)
2009/12 Mechanisms and targets of cytokine-induced retinal endothelial cell permeability 1st Annual Meeting of IBILI
Institute of Biomedical Research in Light and Image (IBILI), Faculty of Medicine, University of Coimbra (Coimbra, Portugal)
2009/06 TNF-a increases retinal endothelial cell permeability through PKCz/NF-kB activation 11th Meeting of the Portuguese Society for Neurosciences
(Braga, Portugal)
2008/12 Mechanisms and targets of cytokine-induced retinal endothelial cell permeability Graduate students seminars series, Department of Cellular and Molecular Physiology, Penn State College of Medicine
(Hershey, Pennsylvania, Estados Unidos)
2008/10 The action of pro-inflammatory cytokines on retinal endothelial cell barrier permeability: protective effect of corticosteroids Special Interest Symposium: The role of inflammation in diabetic retinopathy session at the “European Association for Vision and Eye Research - EVER 2008
(Portoroz, Eslovénia)
2008/06/05 Pro-Inflammatory cytokines increase retinal rndothelial cell permeability: Protective effect of dexamethasone "Penn State Hershey Eye and Vision Research Day”, Penn State College of Medicine
(Hershey, Pennsylvania, Estados Unidos)
2008/02 Mechanisms of cell dysfunction in early Diabetic Retinopathy Young Scientists Seminar, Center for Neurosciences and Cell Biology
(Coimbra, Portugal)
2007/12 Pro-inflammatory cytokines-induced increase in retinal endothelial cell permeability: protective effect of dexamethasone V CNC Annual Meeting
(Coimbra, Portugal)
2006/12 High glucose, nitric oxide and H2O2 induce apoptosis by a caspase-independent pathway in retinal endothelial cells IV Encontro Annual do CNC – Reunião Annual do Programa Doutoral em Biologia Experimental e Biomedicina
(Cantanhede, Portugal)
2004/12 Mechanisms of cellular dysfunction in Diabetic Retinopathy: Involvement of inflammatory mediators 1st Annual Meeting of Graduate Programs in Biosciences
(Porto, Portugal)
2004/11 Heme oxygenase-1 response to diabetes, hyperglycemia and oxidative stress in retinas and endothelial cells IV Congresso de Investigação em Medicina, Pedagogia e Ciência
(Coimbra, Portugal)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2023/11 - Atual The links between BAR domain proteins endophilin-A and BIN1 and neurodegeneration.
Coorientador
 Pharmaceutical Sciences (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/01 - Atual The role of skin senescence to whole body ageing
Coorientador
 Ciências Farmacêuticas (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/03 - Atual Neuropeptide Y (NPY) system as a new target to delay aging
Coorientador de Marisa Ferreira Marques
 Ciências Farmacêuticas (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/01 - 2022/06 Mechanotransduction meets autophagy: implications and opportunities in Alzheimer's disease
Coorientador de Heloísa Salguinho Gerardo
 Ciências Farmacêuticas (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2020/09 - 2021/12 Targeting the endocrine system to slow down aging in Hutchinson-Gilford Progeria Syndrome
Orientador de Ana Carolina Real
 Investigação Biomédica (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2021/01 - 2021/07 The hypothalamus as a key player in the metabolic dysfunction of Hutchinson-Gilford progeria syndrome
Orientador
 ERASMUS BSc student of Health Biology bachelor degree (Licenciatura/Bacharelato)
Universidad de Alcalá Facultad de Ciencias, Espanha
2019/09 - 2020/11 A neuroendocrine strategy to delay aging
Orientador
 Ciências Biomédicas (Mestrado)
Universidade do Algarve Centro de Investigação em Biomedicina, Portugal

Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2018/09 - 2020/01 Silencing of CYPX gene in the hypothalamus and its impact on whole-body metabolism
Coorientador de Adriana Arrulo Pereira
 Oncobiologia (Mestrado)
Universidade do Algarve Centro de Investigação em Biomedicina, Portugal

Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2018/09 - 2019/07 Neuroendocrine peptide as a novel therapeutic strategy to delay skin aging
Coorientador de Ana Catarina da Silva Franco
 Biotecnologia Farmacêutica (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/09 - 2019/07 Gastrointestinal Tract Alterations In A Mouse Model Of Progeria
Coorientador de Inês João Dinis Ferreira
 Farmacologia Aplicada (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/04 - 2018/07 The effect of a novel caloric restriction mimetic on neurogenesis regulation in the hypothalamus
Orientador de Ana Catarina Paulino do Ó Vinhas
 Ciências Biomédicas (Licenciatura/Bacharelato)
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2016/07 - 2017/09 Ghrelin administration as a novel strategy to delay aging in Hutchinson-Gilford Progeria Syndrome
Orientador de André Carlos Silva Ferreira de Carvalho
 Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/01 - 2017/07 Age-related alterations in the liver of a mouse model of Hutchinson-Gilford Progeria Syndrome
Orientador de Carolina Eugénia Soares Cordeiro Marcelino Pinto
 Ciências Biomédicas (Licenciatura/Bacharelato)
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2017/01 - 2017/07 Age-related histopathological alterations in the skin of a mouse model of Hutchinson-Gilford Progeria Syndrome
Orientador de Cláudia Rego Rodrigues
 Biotecnologia (Licenciatura/Bacharelato)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2015/09 - 2016/09 Strategies to reverse cellular senescence and enhance progerin clearance in Hutchinson-Gilford progeria syndrome cells
Orientador de Ana Sofia Marques Leal
 Investigação Biomédica (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015/09 - 2016/09 Neuropeptide Y: a novel therapeutic strategy to ameliorate age-related diseases and increase lifespan
Coorientador de Joana Filipa Costa Pereira
 Biotecnologia Farmacêutica (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2011/09 - 2013/09 Autophagy in cortical neurons: role of caloric restriction and neuropeptide Y
Orientador
 Bioquímica (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2023/06/26 - 2023/07/07 Ageing: from fundamental biology to societal impact", EIT Health Ageing PhD School advanced course (2023/06/26 - 2023/07/07)
Outro (Membro da Comissão Organizadora)
 Universidade de Coimbra, Portugal
2017/10/30 - 2017/10/30 Postdoc@UC Day 2016 - Engage and connect. Rómulo Centro Ciência Viva, Physics Department, University of Coimbra, Portugal. Website: https://www.uc.pt/iii/postdoc/postdocday2017 (2017/10/30 - 2017/10/30)
Outro (Membro da Comissão Organizadora)
 Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2016/11/10 - 2016/11/10 Postdoc@UC Day 2016 - Stir up the initiative. Institute for Interdisciplinary Research, Casa Costa Alemão, University of Coimbra, Portugal Website: https://www.uc.pt/iii/postdoc/postdocday2016 (2016/11/10 - 2016/11/10)
Outro (Membro da Comissão Organizadora)
 Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2016/09/30 - 2016/09/30 1st Symposium on Aging Research @CNC - Molecular Mechanisms of Aging and Age-Related Diseases. Center for Neuroscience and Cell Biology, University of Coimbra, Portugal Website: http://agingsymposium.wixsite.com/2016 (2016/09/30 - 2016/09/30)
Simpósio (Membro da Comissão Organizadora)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/10/30 - 2015/10/30 Postdoc@UC Day 2015 – Crossing borders. Faculty of Arts and Humanities, University of Coimbra, Portugal Website: http://www.uc.pt/en/iii/postdoc/postdocday2015 (2015/10/30 - 2015/10/30)
Outro (Membro da Comissão Organizadora)
 Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2022/09/30 - Atual Participation in scientific divulgation related activities, as part of the International Researchers Night 2022
Outro
Universidade de Coimbra - Instituto Multidisciplinar do Envelhecimento (MIA-PORTUGAL), Portugal
2019 - Atual Participation in society-targeted video interview “ASK (Always Seeking Knowledge) Researchers”, organized by organization of Center for Neuroscience and Cell Biology, University of Coimbra, Portugal.
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/07/16 - Atual Biostastistics for Research Workshop
Oficina (workshop)
Universidade de Coimbra Faculdade de Medicina, Portugal
2023/03 - 2023/03 Participation in scientific divulgation related activities, as part of the Program Brain Awareness Week 2023
Outro
Universidade de Coimbra - Instituto Multidisciplinar do Envelhecimento (MIA-PORTUGAL), Portugal
2022/06/27 - 2022/07/08 Ageing: from fundamental biology to societal impact - EIT Health Ageing PhD School advanced course
Outro
University of Coimbra - EIT Health Ageing PhD School, Portugal
2022/04/02 - 2022/04/08 1st Ageing Spring School 2022
Simpósio
Universidade de Coimbra Multidisciplinary Institute of Ageing, Portugal
2017/09/29 - 2017/09/29 Participation in scientific divulgation related activities, as part of the “International Researchers’ Night 2017”.
Outro
 Noite Europeia dos Investigadores 2017
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2017/03/13 - 2017/03/19 Participation in scientific divulgation related activities, as part of the Program "Brain Awareness Week 2017".
Outro
 Brain Awareness Week 2017
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2016/03/13 - 2016/03/19 Participation in scientific divulgation related activities, as part of the Program “Brain Awareness Week 2016”.
Outro
 Brain Awareness Week 2016
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/03/14 - 2015/03/21 Participation in scientific divulgation related activities, as part of the Program “Brain Awareness Week 2015".
Outro
 Brain Awareness Week 2015
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/02/18 - 2015/03/20 IneoStart (Curso de Especialização Tecnológica)
Oficina (workshop)
Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal
2014/09/26 - 2014/09/26 Participation in scientific divulgation related activities, as part of the “International Researchers’ Night 2014”.
Outro
 International Researchers’ Night 2014
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014/03/29 - 2014/03/29 Participation in scientific divulgation related activities, as part of the Program “Conversas com Cientistas”.
Outro
 Conversas com Cientistas
Instituto de Educação e Cidadania (IEC), Portugal
2014/03/12 - 2014/03/14 Hands-On Course on Microscopy Imaging Analysis
Oficina (workshop)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/03/11 - 2013/03/17 Participation in scientific divulgation related activities, as part of the Program “Brain Awareness Week 2013”.
Outro
 Brain Awareness Week 2013
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2010/04/26 - 2010/05/07 IX Course on Laboratory Animal Science, FELASA level C certification
Outro
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal

Universiteit Utrecht, Países Baixos
2009/02/09 - 2009/02/13 "Visual Neuroscience: From photons to perception" - Doctoral Programme in Experimental Biology and Biomedicine advanced course
Outro
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2005/07/05 - 2005/07/10 FENS/Blackwell Summer School - Neuro-glia interaction in aging and disease
Outro
Federation of European Neuroscience Societies, Bélgica

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2023/12/12 In vivo reversion of progeria phenotypes by cyclic induction of the FOXM1 transcription factor
Arguente
 Maria Inês Cabral Ala (Mestrado)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2023/12/11 BIOENGINEERED APPROACHES FOR STUDYING AND TREATING CARDIAC DISEASE OR AGEING
Arguente
 Luís Miguel de Almeida Monteiro (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2023/11/10 Modulation of a RBP as potential therapeutic strategy for SCA2
Arguente principal
 Filipa Lopes Couto (Mestrado)
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2023/09/21 EXPLORING THE PERIPHERAL CROSSTALK BETWEEN DOPAMINE AND NPY IN THE REGULATION OF ENERGY BALANCE
Arguente
 Eduardo José Baptista Lopes (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022/11/03 Obstructive Sleep Apnea as an Aging Trigger: from Mechanisms to Biomarkers
Arguente
 Laetitia da Silva Gaspar (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2022/02/28 Selection of Purification Methods and AAV Serotypes for CNS Transduction
Arguente principal
 Beatriz Sofia Leal da Silva (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022/02/25 Effect of blueberry juice supplementation in a rat model of prediabetes: control diets and molecular mechanisms
Arguente principal
 Gonçalo da Costa Rodrigues Ferreira (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/12/16 TARGETING THE ENDOCRINE SYSTEM TO SLOW DOWN AGING IN HUTCHINSON-GILFORD PROGERIA SYNDROME
Orientador
 Ana Carolina Martins Real (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2021/12/10 Estudos Para Estabelecimento de um Modelo de Senescência Celular adequado a Screening Farmacológico
Arguente principal
 Eliana Rita de Almeida Barbosa (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/12/09 JOURNEY TO THE CENTER OF THE CELL: TARGETING THE NUCLEUS IN FAMILIAL DILATED CARDIOMYOPATHY
Arguente principal
 Tatiana Patrícia Ferreira Estima (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2021/12/03 NOVEL MOLECULAR TARGETS AND THERAPEUTIC STRATEGIES FOR HUTCHINSON-GILFORD PROGERIA SYNDROME’S CARDIOVASCULAR SYSTEM
Arguente principal
 Simão Correia Brás dos Santos (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/01/09 The role of ageing in polyglutamine-induced neurodegeneration. A study in Machado-Joseph disease models
Vogal
 Dina Maria da Silva Rodrigues Pereira (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2019/09/27 The role of neuropeptide Y in articular chondrocyte functions
Arguente principal
 Caren Jane Rodrigues (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2019/09/13 Prenatal glucocorticoids and physical exercise in adolescence: effects on behaviour and hypothalamic microglia
Arguente principal
 Sofia dos Reis Galvão (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2019/09/10 Talk Your Heart Out: Unveiling the Path Between Endothelial Cells and Cardiomyocytes Communication in HFpEF
Arguente principal
 Catarina do Nascimento Jorge (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2019/07/30 Neuroendocrine peptide as a novel therapeutic strategy to delay skin aging
Orientador
 Ana Catarina da Silva Franco (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/07/29 Gastrointestinal tract alterations in a mouse model of progeria
Orientador
 Inês João Dinis Ferreira (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/07/24 Effect of dual therapy with liraglutide and ghrelin on brain metabolism and intracellular stress in the Huntington's disease R6/2 mouse model
Arguente
 Débora Tatiana de Sousa Mena (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/09/26 Autophagy activation by let-7 alleviates motor and neuropathological deficits in a transgenic mice model of Machado-Joseph disease
Arguente
 Beatriz Filipa Varela Estremores (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/09/25 Impact of maternal diabetes on offspring memory
Arguente principal
 Fábio de Jesus Ribeiro de Sousa (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/09/15 Ghrelin administration as a novel strategy to delay aging in Hutchinson-Gilford Progeria Syndrome
Orientador
 André Carlos Silva Ferreira de Carvalho (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/07/28 Identification of Neuropeptide Y receptors in human articular cartilage: influence of gender and osteoarthritis
Arguente principal
 Inês Sofia dos Santos Rodrigues Ferreira (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2016/09/23 PERK inhibition role in Spinocerebellar ataxias
Arguente principal
 Marco António Rodrigues Ferreira (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2016/09/09 Strategies to reverse cellular senescence and enhance progerin clearance in Hutchinson-Gilford Progeria Syndrome cells
Orientador
 Ana Sofia Marques Leal (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2016/09/08 Insights into the role of stress granules in spinocerebellar ataxias
Arguente principal
 Sandra Marisa Oliveira Tomé (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016/09/08 Autophagy dysregulation in models of Machado-Joseph disease and Parkinson's disease
Arguente principal
 Chiara Soricelli (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016/02/16 Neuropeptide Y gene transfer for neuroprotection in Machado-Joseph disease
Vogal
 Joana Filipa Duarte das Neves (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2015/09/11 Pharmacological modulation of mutant ataxin-3 translation and it potential therapeutic effect in Machado-Joseph disease
Arguente principal
 Filipa Alexandra Ferreira de Brito (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2015/07/14 4-hydroxynonenal - a product of lipid peroxidation as a histone modifier
Arguente principal
 João Pedro Santiago de Jesus (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015/07/02 Interaction between Cx43 and LC3 directs gap junctions to ubiquitin-independent autophagy degradation
Arguente principal
 Rita Rodrigues Sá Ferreira (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2014/09/26 Multipotent mesenchymal stromal cells for Machado-Joseph disease therapy
Arguente principal
 Teresa Maria Pereira da Silva (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2014/09/22 Involvement of NPY system in the inflammatory responses mediated by retinal microglial cells: Modulation by itagliptin
Arguente principal
 Sandra Raquel Félix Guimarães Correia (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2014/09/11 Berberine modulation on doxorubicin-induced cell death and autophagy
Arguente principal
 Tatiana Isabel Rodrigues Martins (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014/07/15 Modulation of the Wnt/ß-Catenin pathway in obesity - a role for bile acid metabolic improvement
Arguente principal
 Inês Catarina Marouvo Simões (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/09/30 Modulation of pro-inflammatory respondes in the retina by Neuropeptide Y – the role of NPY Y1 receptor
Arguente
 Filipe Manuel Rijo Mendes Martins Elvas (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2013/09/18 Autophagy in cortical neurons: role of caloric restriction and neuropeptide Y
Orientador
 Marisa Ferreira Marques (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/07/30 Effects of ghrelin on hippocampal glutamate receptors and neuronal morphology
Arguente
 Joni Fiona Van Leeuwen (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012/07/23 Impact of methamphetamine on astrocytes and endothelial cells: role of aquaporin-4
Arguente principal
 Ricardo Alexandre Gomes Leitão (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010/11/19 Looking at tricellulin expression in the brain
Arguente principal
 Cibelle Neiva Cavalcanti Mariano (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2022 - Atual Frontiers in Aging - Guest Editor
2022 - Atual Frontiers in Cellular Neuroscience - Guest Editor
2022 - Atual Frontiers in Pharmacology
2020/11 - Atual Frontiers in Aging - Review Editor
2020 - Atual Aging Cell (1474-9718) John Wiley & Sons on behalf of the Anatomical Society
2017 - Atual Scientific Reports (2045-2322) Springer Science and Business Media LLC
2021 - 2021 Frontiers in Neuroscience (1662-4548)
2020 - 2020 BioMed Research International (2314-6141) Hindawi Publishing Corporation
2011 - 2020 Investigative Ophthalmology & Visual Science (0146-0404) Association for Research in Vision and Ophthalmology
2019 - 2019 Journal of Endocrinology (1479-6805) Bioscientifica on behalf of the Society for Endocrinology
2018 - 2018 Diabetes Care (0149-5992) American Diabetes Association
2012 - 2016 Diabetes American Diabetes Association
2010 - 2016 Ophthalmic Research (1423-0259) S. Karger AG
2012 - 2012 Nutrients (2072-6643) MDPI AG
2011 - 2011 FEBS Letters (1873-3468) Wiley (John Wiley & Sons)
2009 - 2009 Journal of Biomedicine and Biotechnology (1110-7251) Hindawi Limited

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2023/01/04 - Atual Hypothalamus: a target to delay aging? Lecturer in Seminars in Biomedicine advanced course. Master in Molecular Biomedicine. (Mestrado) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2022/12/05 - Atual Defective synaptic vesicle endocytosis: a trigger for neuronal senescence? Lecturer in Cell Regulation and Signalling advanced course. PhD on Health Science. (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal
2022/11/26 - Atual Autophagy: a driver of aging and age-related diseases.Lecturer in Molecular mechanisms of the diseases and biological models advanced course. Master in Pharmaceutical Biotechnology. (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2023/05/08 - 2023/07/09 Role of the hypothalamus in ageing. Lecturer in Ageing advanced course. Master of Cellular and Molecular Biology. (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2023/05/08 - 2023/06/09 Caloric restriction and longevity. Lecturer in "Ageing" advanced course - Master in Cellular and Molecular Biology. (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022/05/02 - 2022/06/03 Caloric restriction and longevity. Lecturer in "Ageing" advanced course - Master in Cellular and Molecular Biology. Master in Cellular and Molecular Biology (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022/05/02 - 2022/06/03 Role of the hypothalamus in ageing. Lecturer in Ageing advanced course. Master of Cellular and Molecular Biology. Master in Cellular and Molecular Biology (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022/01/26 - 2022/01/26 Hypothalamus: a target to delay aging. Lecturer advanced course Seminars in Biomedicine Master in Molecular Biomedicine (Mestrado) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2021/11/30 - 2021/11/30 Targeting the proteostasis network to delay premature aging in Progeria. Lecturer advanced course “Cell Regulation and Signalling" PhD Program on Health Science (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal
2021/11/20 - 2021/11/20 Autophagy: a driver of aging and age-related diseases. Lecturer advanced course ¿Molecular mechanisms of the diseases and biological models" Master in Pharmaceutical Biotechnology (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/02/01 - 2021/02/19 Caloric restriction and longevity. Lecturer - advanced course Ageing. Master in Cellular and Molecular Biology/Neurasmus (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021/02/01 - 2021/02/19 Role of the hypothalamus in ageing. Lecturer - advanced course "Ageing". Master in Cellular and Molecular Biology/Neurasmus (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/11/25 - 2020/11/25 Targeting the proteostasis network to delay premature aging in Progeria. Lecturer - advanced course Cell Regulation and Signalling. PhD Program on Health Sciences (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal
2019/11/25 - 2019/11/25 Targeting the proteostasis network to delay premature aging in Progeria. Lecture - advanced course Cell Regulation and Signalling. PhD Program on Health Sciences (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal
2019/11/16 - 2019/11/16 Molecular mechanisms of aging and aging experimental models. Lecture - advanced course Molecular mechanisms of the diseases and biological models. Master in Pharmaceutical Biotechnology (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/11/13 - 2019/11/13 Cellular senescence. Lecture - advanced course Cellular Regulation. High school "Escola Secundária Marques de Castilho", Águeda, Portugal. (Ensino secundário) Instituto de Educação e Cidadania (IEC), Portugal
2019/10/25 - 2019/10/25 Hypothalamus: a target to delay aging. Lecture - advanced course Foundations of Science. Master in Biomedical Research (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2019/10/24 - 2019/10/24 Hypothalamus: a target to delay aging. Lecture - advanced course Neuroscience. Master in Molecular Biomedicine (Mestrado) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2019/05/21 - 2019/05/21 Caloric restriction and longevity and Role of the hypothalamus in ageing. Lectures - advanced course Ageing. Master in Cellular and Molecular Biology/Neurasmus (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/03/08 - 2019/03/08 Cellular senescence. Lecture - advanced course Cellular Regulation. High school "Escola Secundária de Anadia". Anadia, Portugal. (Ensino secundário) Instituto de Educação e Cidadania (IEC), Portugal
2018/12/07 - 2018/12/07 Cellular senescence. Lecture - advanced course Cellular Regulation. High school "Escola Secundária Adolfo Portela". Águeda, Portugal. (Ensino secundário) Instituto de Educação e Cidadania (IEC), Portugal
2018/05/25 - 2018/05/25 Caloric restriction and longevity. Lecture - advanced course Ageing. Master in Cellular and Molecular Biology/Neurasmus (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/04/07 - 2018/05/24 Coordinator and principal lecturer of the Advanced course “Metabolism and Aging: searching for the elixir of youth” (7 theoretical/practical classes; 2.5h each) to undergraduate students, high school students and teachers, under the program “Science in Action”. (Outros) Instituto de Educação e Cidadania (IEC), Portugal
2018/03/13 - 2018/03/13 Potential of (neuro)peptides for treatment of Progeria patients. Lecture - advanced course Ageing: from cellular processes to the organism. Doctoral Programme in Experimental Biology and Biomedicine (Doutoramento) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2018/02/24 - 2018/02/24 Cellular senescence. Lecture - advanced course ¿Cellular Regulation. High school "Instituto Educativo de Souselas", Souselas, Coimbra, Portugal. (Ensino secundário) Instituto de Educação e Cidadania (IEC), Portugal
2018/02/21 - 2018/02/21 New therapeutic strategies to delay premature aging in Progeria. Lecture - Theoretical/practical classes of Pharmacology II, Medicinal Chemistry BSc degree. Medicinal Chemistry (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal

Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/11/24 - 2017/11/24 "Progeria: an accelerated aging disease". Seminar - Gene and Cell Therapy curricular unit Seminars. Biomedical Sciences (Bacharelato) Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2017/11/11 - 2017/11/11 Autophagy and neurodegenerative diseases. Lecture - advanced course Molecular mechanisms of the diseases and biological models. Master in Pharmaceutical Biotechnology (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/06/16 - 2017/06/16 Progeria: pathophysiology and potential therapies. Lecture - Thematic Seminars curricular unit, Master in Applied Pharmacology. Master in Applied Pharmacology (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/04/15 - 2017/04/15 Cellular senescence. Lecture - advanced course Cellular Regulation. High school "Escola Secundária Marques de Castilho", Águeda, Portugal. (Ensino secundário) Instituto de Educação e Cidadania (IEC), Portugal
2017/04/06 - 2017/04/06 Caloric restriction and longevity. Lecture - advanced course Ageing. Master in Cellular and Molecular Biology/Neurasmus Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/01/19 - 2017/01/19 Cellular senescence. High school "Agrupamento de escolas de Penacova", Penacova, Coimbra, Portugal. (Ensino secundário) Agrupamento de escolas de Penacova, Portugal
2016/11/26 - 2016/11/26 Autophagy and neurodegenerative diseases. Lecture - advanced course Molecular mechanisms of the diseases and biological models. Master in Pharmaceutical Biotechnology (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2016/11/11 - 2016/11/11 Cellular senescence. Lecture - advanced course Cellular Regulation. High school "Instituto Educativo de Souselas", Souselas, Portugal. (Ensino secundário) Instituto de Educação e Cidadania (IEC), Portugal
2016/04/21 - 2016/04/21 “Caloric restriction and longevity”. Llecture - advanced course “Ageing”. Master in Cellular and Molecular Biology/Neurasmus (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016/02/23 - 2016/02/23 “Progeria: pathophysiology and potential therapies”. Lecture - Thematic Seminars curricular unit, Master in Applied Pharmacology. Master in Applied Pharmacology (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2015/04/27 - 2015/04/27 “Caloric restriction and longevity” . Lecture - advanced course “Ageing”. Master in Cellular and Molecular Biology/Neurasmus (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015/04/10 - 2015/04/10 “Experimental models to study Aging”. Lecture - Theoretical/practical classes of Pharmacology II, Medicinal Chemistry BSc degree. Medicinal Chemistry (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal

Universidade de Coimbra Faculdade de Medicina, Portugal

Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015/03/06 - 2015/03/06 “Progeria: an accelerated aging disease”. Lecture - Thematic Seminars curricular unit, Master in Applied Pharmacology. Master in Applied Pharmacology (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2014/04/29 - 2014/04/29 “Caloric restriction and longevity” . Lecture - advanced course “Ageing”. Master in Cellular and Molecular Biology/Neurasmus (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/10 - 2013/12 Pratical classes of Histology, Integrated Master in Pharmaceutical Sciences. Integrated Master in Pharmaceutical Sciences (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2013/04/29 - 2013/04/29 “Caloric restriction and lifespan”. Lecture - advanced course “Ageing”. Master in Cellular and Molecular Biology (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011/11 - 2011/11 Pratical classes of Histology, Integrated Master in Pharmaceutical Sciences. Integrated Master in Pharmaceutical Sciences (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2010/11/10 - 2010/11/10 “Autophagy and neurodegeneration”. Lecture - advanced course “Molecular mechanisms of the diseases and biological models”. Master in Pharmaceutical Biotechnology (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2010/11 - 2010/11 Pratical classes of Histology, Integrated Master in Pharmaceutical Sciences. Integrated Master in Pharmaceutical Sciences (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2009/02 - 2009/02 “Mechanisms and targets of TNF-a-induced retinal endothelial cell permeability”. Lecture - advanced course “Visual Neuroscience: From photons to perception”. Doctoral Programme in Experimental Biology and Biomedicine (Doutoramento) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2005/05 - 2005/05 “Retinal neurodegenerative diseases – Glaucoma”. Lecture - advanced course Visual Neurobiology, Master in Vision Sciences. Master in Vision Sciences (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2004/02 - 2004/02 “Retinal neurodegenerative diseases – Glaucoma”. Lecture - advancd course Visual Neurobiology, Master in Vision Sciences. Master in Vision Sciences (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal

Membro de associação

Nome da associação Tipo de participação
2017 - Atual Portuguese Society of Pharmacology Full member

Tutoria

Tópico Nome do aluno
2020/02/03 - Atual Biochemistry and Molecular and Cell Biology Master Student Laboratory Supervision Ana Cláudia Bessa
2018/09/01 - Atual Pharmaceutical Sciences Master Student Laboratory Supervision Inês Oliveira
2020/01/06 - 2020/01/24 Biomedical Research Master Student Laboratory Supervision Carolina Santos
2018/09/03 - 2018/09/07 Laboratory Supervision Ciência Viva no Laboratório - Ocupação Científica de Jovens nas Férias 2018
2017/07/24 - 2017/07/28 Laboratory Supervision Ciência Viva no Laboratório - Ocupação Científica de Jovens nas Férias 2017
2012/04 - 2017/06 PhD Student Laboratory Supervision Sara Carmo Silva
2017/04/10 - 2017/04/12 Laboratory Supervision Estágios Científicos do IEC
2016/12/21 - 2016/12/23 Laboratory Supervision Estágios de Natal no CNC
2011/01 - 2016/03 PhD Student Laboratory Supervision Mariana Botelho da Rocha
2012/07/09 - 2012/07/20 Laboratory Supervision Ciência Viva no Laboratório - Ocupação Científica de Jovens nas Férias 2012
2012/04 - 2012/07 Biochemistry BSc Student Laboratory Supervision Helena Martins
2010/09 - 2011/09 Biomedical Sciences Master Student Laboratory Supervision Jorge Filipe da Conceição Pascoal
2011/07/11 - 2011/07/22 Laboratory Supervision Ciência Viva no Laboratório - Ocupação Científica de Jovens nas Férias 2011
2010/07/12 - 2010/07/23 Laboratory Supervision Ciência Viva no Laboratório - Ocupação Científica de Jovens nas Férias 2010
2006/09 - 2007/09 Pharmaceutical Sciences BSc Student Laboratory Supervision Luzia Margarida Tavares
2005/09 - 2006/09 Biochemistry BSc Student Laboratory Supervision Núria Filipa Serrador Simões
2004/09 - 2005/09 Biochemistry BSc Student Laboratory Supervision Carolina Rita Sousa Fernandes
2004/09 - 2005/09 Biology BSc Student Laboratory Supervison Rita Isabel de Morais Meirinhos
2003/09 - 2004/09 Biochemistry BSc Student Laboratory Supervision Áurea Filipa de Aguiar Castilho
2003/09 - 2004/09 Biochemistry BSc Student Laboratory Supervision Andreia Mónica Pedrosa Correia Serra
Distinções

Prémio

2018 2nd edition Janssen Innovation Award - Neuroscience. Carmo-Silva S, Nóbrega C, Ferreira-Marques M, Botelho M, Aveleira CA, Pereira de Almeida L, Cavadas C.
2016 FCT Investigator Programme. Foundation for Science and Technology (FCT), Portugal. Célia Aveleira. Research project: Ghrelin: a new therapeutic strategy to delay aging through hypothalamic control.
2015 Progeria Research Foundation Innovator Award Research Grant. Aveleira, CA. Research project: Ghrelin: a novel therapeutic intervention to rescue the phenotype of Hutchinson-Gilford Progeria Syndrome.
Progeria Research Foundation, Estados Unidos
2015 Post-Doctoral fellowship. Foundation for Science and Technology (FCT), Portugal. Célia Aveleira. Research Project: Ghrelin: a new therapeutic strategy to delay aging through hypothalamic control.
2011 Post-Doctoral fellowship. Foundation for Science and Technology (FCT), Portugal. Célia Aveleira. Research project: Neuropeptide Y as a caloric restriction mimetic: a new target for aging?
2005 Best Poster Award. 15th Meeting of the European Association for the Study of Diabetes - Eye Complications Study Group (EASDec). Aveleira CA, Castilho A Leal E, Serra A, Álvaro AR, Fernandes C, Meirinhos R, AmbrósioAF.
2004 PhD fellowship. Foundation for Science and Technology (FCT), Portugal. Célia Aveleira. Research Project: The role of interleukin-1 beta in blood-retinal barrier breakdown in the early stages of Diabetic Retinopathy.

Outra distinção

2004 Best Poster Award. Annual Meeting of the European Association for Vision and Eye Research – EVER. C.A. Aveleira, E.C. Leal, A. Castilho, A. Serra and A.F. Ambrósio.
2002 Dr. Ernesto Roma Award - Honorable Mention. Ernesto Roma Awards - Roche Diagnostics 2002. Manuel Carlos Lemos, Célia Aveleira, Leonor Gomes, Fernando Jesus Regateiro e Manuela Carvalheiro.