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Andrea Patricia Ribeiro da Cruz. Concluiu o(a) Doutoramento em Ciências da Saúde em 2007 pelo(a) Universidade do Minho.
Identificação

Identificação pessoal

Nome completo
Andrea Patricia Ribeiro da Cruz

Nomes de citação

  • Cruz, Andrea
  • Andrea P Cruz
  • Andrea Cruz
  • Cruz, A

Identificadores de autor

Ciência ID
5215-C811-51C2
ORCID iD
0000-0002-1662-3072

Endereços de correio eletrónico

  • andreaprcruz@gmail.com (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Ciências da Saúde
  • Ciências da Engenharia e Tecnologias - Nanotecnologia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Francês Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2)
Formação
Grau Classificação
2007
Concluído
 Ciências da Saúde (Doutoramento)
Especialização em Ramo: Ciências Biológicas e Biomédicas
Universidade do Minho, Portugal
"Understanding Bcg Vaccination:implications for the Design of New Preventive Strategies Against Mycrobacteriosis" (TESE/DISSERTAÇÃO)
2000/07/30
Concluído
 Biomedial Sciences (Master)
The Montfort University, Reino Unido
1999/06/30
Concluído
 Microbiologia (Licenciatura)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/06/01 - Atual Investigador Auxiliar (carreira) (Investigação) International Iberian Nanotechnology Laboratory, Portugal
International Iberian Nanotechnology Laboratory, Portugal
2020/01/01 - 2022/05/31 Investigador Auxiliar (carreira) (Investigação) Prochild CoLab Against Poverty ans Social Exclusion, Portugal
Prochild CoLab Against Poverty ans Social Exclusion, Portugal
2016/03/01 - 2019/12/31 Investigador (Investigação) International Iberian Nanotechnology Laboratory, Portugal
International Iberian Nanotechnology Laboratory, Portugal
2013/05/01 - 2016/02/27 Pós-doutorado (Investigação) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2007/04/01 - 2013/04/30 Pós-doutorado (Investigação) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2009/01/01 - Atual Professor Adjunto Convidado (Docente Ensino Superior Politécnico) Universidade do Minho, Portugal
Universidade do Minho Escola Superior de Enfermagem, Portugal
Projetos

Projeto

Designação Financiadores
2022 - 2025 Lifesaver Project
Agreement Number: 101036702
Investigador
International Iberian Nanotechnology Laboratory, Portugal
 Horizon 2020 Framework Programme
Em curso
2018 - 2019 Develop a biosensor for coloretal cancer diagnosis and monitoring
INTERREG V-A España-Portugal (POCTEP)
INTERREG V-A España-Portugal (POCTEP)
Investigador
Concluído
2017 - 2019 Uncovering the mechanistic assembly and function of actin ring networks in axonal biology and pathology
PTDC/MED-NEU/28623/2017
Investigador
International Iberian Nanotechnology Laboratory, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2016 - 2019 FP7-COF-NANOTRAIN
refª 600375
Investigador
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Concluído
2017/09 - 2018/09 Tears4life - a biosensor for glioma detection
Tears4life
Investigador responsável
Life and Health Sciences Research Institute (ICVS) and International Iberian Nanotechnology Laboratory (INL)
Concluído
2013/06 - 2016/02 Cell homeostasis tissue organisation and organism biology
NORTE-07-0124-FEDER-000003
Bolseiro de Pós-Doutoramento
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 FEDER ON.2-QREN
Concluído
2009 - 2013 BCG vaccination: a tool to identify new correlates of protection and pathology in experimental infection with Mycobacterium tuberculosis
PTDC/SAU-MII/101977/2008
Investigador
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2006 - 2011 Role of Interleukin-23 (IL-23) and IL-17 in the regulation of the immune response to the infection by Mycobacterium tuberculosis Infection
PTDC/SAU-MII/70895/2006
Investigador
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para Ciência e Tecnologia
Concluído
2007 - 2010 Reconstitution and homeostasis of the immune system following HIV-infection
PIC/IC/83313/2007
Investigador
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Teixeira, Diogo; Cruz, Andrea; Bráz, Sandra; Moreira, Alexandra; Relvas, João; Camacho, Rui. "PBS Finder". Trabalho apresentado em 30th Annual ACM Symposium on Applied Computing, Salamanca, 2015.
    Publicado
  2. Teixeira, Diogo; Cruz, Andrea; Bráz, Sandra; Moreira, Alexandra; Relvas, João; Camacho, Rui. "PBS Finder: a tool to assist RNA Binding Proteins studies". 2015.
    10.1145/2695664.2695865
  3. Cruz, Andrea; Carmona, Jenny; Carole Sousa, Nuno S. Osório, Ana L. Saraiva, Stefan Svenson, Gunilla Kallenius, Jorge Pedrosa, Fernando Rodrigues, Antó; Carmona, J.; Fraga, AG; Sousa, C.; Costa, P; et al. "Mycobacterium tuberculosis strains are differentially recognized by TLRs with an impact on innate immune responses and the outcome of infection". Trabalho apresentado em European Congress of Immunology, 2012.
  4. Marcos, N; Pinho, S.; Grandela, C.; Cruz, Andrea; Samyn-Petit, B.; Harduin-Lepers, A.; Silva, F; et al. "Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen". Trabalho apresentado em Mucins in Health and Disease 7th International Workshop on Carcinoma associated Mucins, 2004.
    Publicado
  5. Cruz, Andrea; Pearl, John; Khader, S.A.; Solache, A; Pedrosa, J; Castro, AG; Cooper, Andrea M.. "BCG Infection Induces IL-17 Producing Antigen-Specific T cells". Trabalho apresentado em 12th Annual International Congress of Immunology/4th Annual Conference of the Federation-of-Clinical-Immunology-Societies (FOCIS), 2004.
Artigo em revista
  1. Francisca Melo-Fonseca; Michael Gasik; Andrea Cruz; Daniel Moreira; Filipe S. Silva; Georgina Miranda; Inês Mendes Pinto. "Engineering a Hybrid Ti6Al4V-Based System for Responsive and Consistent Osteogenesis". ACS Omega (2024): http://dx.doi.org/10.1021/acsomega.3c07232.
    10.1021/acsomega.3c07232
  2. Melo-Fonseca, Francisca ; Gasik, Michael; Cruz, Andrea; Moreira, Daniel; Silva, Filipe Samuel; Miranda, Georgina; Mendes Pinto, Inês. Autor correspondente: Mendes Pinto, Inês. "Engineering a hybrid Ti6Al4V-based system for responsive and consistent osteogenesis". ACS Omega (2024): doi: 10.1021/acsomega.3c07232.
    Publicado
  3. Andrea Cruz; Elisabete Fernandes; Raquel O. Rodrigues; Susana O. Catarino; Diana Pinho. "Editorial: Disease-on-a-chip: from point-of-care to personalized medicine". Frontiers in Pharmacology (2023): http://dx.doi.org/10.3389/fphar.2023.1344379.
    10.3389/fphar.2023.1344379
  4. Cruz, Andrea; Vieira, Maria; Mesquita, Ana R; Sampaio, Adriana; Mendes Pinto, Inês; Soares, Isabel; Freitas, Paulo. "Non-invasive diagnosis and monitoring tool of children’s mental health: A point-of-care immunosensor for IL-6 quantification in saliva samples". Frontiers in Neuroscience 16 (2022): http://dx.doi.org/10.3389/fnins.2022.919551.
    Publicado
  5. Andrea Cruz; Maria Vieira; Ana R. Mesquita; Adriana Sampaio; Inês Mendes-Pinto; Isabel Soares; Paulo P. Freitas. "Non-invasive diagnosis and monitoring tool of children’s mental health: A point-of-care immunosensor for IL-6 quantification in saliva samples". Frontiers in Neuroscience 16 (2022): http://dx.doi.org/10.3389/fnins.2022.919551.
    10.3389/fnins.2022.919551
  6. Andrea Cruz; Carla M. Carvalho; Alexandra Cunha; Anais Crespo; Águeda Iglesias; Laura García-Nimo; Paulo P. Freitas; Joaquín Cubiella. "Faecal Diagnostic Biomarkers for Colorectal Cancer". Cancers (2021): https://doi.org/10.3390/cancers13215568.
    10.3390/cancers13215568
  7. Sousa, Flávia; Costa-Pereira, Ana Isabel; Cruz, Andrea; Ferreira, Fábio Júnio; Gouveia, Marcos; Bessa, José; Sarmento, Bruno; Travasso, Rui D.M.; Mendes Pinto, Inês. "Intratumoral VEGF nanotrapper reduces gliobastoma vascularization and tumor cell mass". Journal of Controlled Release 339 (2021): 381-390. http://dx.doi.org/10.1016/j.jconrel.2021.09.031.
    10.1016/j.jconrel.2021.09.031
  8. Abreu, Catarina M.; Thomas, Victoria; Knaggs, Paul; Bunkheila, Adnan; Cruz, Andrea; Teixeira, Sofia R.; Alpuim, Pedro; et al. "Non-invasive molecular assessment of human embryo development and implantation potential". Biosensors and Bioelectronics (2020): 112-144. http://dx.doi.org/10.1016/j.bios.2020.112144.
    Publicado • 10.1016/j.bios.2020.112144
  9. Cruz, Andrea; Peng, Weng Kung. "Perspective: Cellular and Molecular Profiling Technologies in Personalized Oncology". Journal of Personalized Medicine 9 3 (2019): 44. http://dx.doi.org/10.3390/jpm9030044.
    10.3390/jpm9030044
  10. Cruz, Andrea; Queirós, Raquel; Abreu, Catarina M.; Barata, Catarina; Fernandes, Rosa; Silva, Rufino; Ambrósio, Antonio F.; et al. "Electrochemical Immunosensor for TNFa-Mediated Inflammatory Disease Screening". ACS Chemical Neuroscience 10 6 (2019): 2676-2682. http://dx.doi.org/10.1021/acschemneuro.9b00036.
    10.1021/acschemneuro.9b00036
  11. Sousa, Flávia; Cruz, Andrea; Pinto, Inês Mendes; Sarmento, Bruno. "Nanoparticles provide long-term stability of bevacizumab preserving its antiangiogenic activity". Acta Biomaterialia 78 (2018): 285-295. http://dx.doi.org/10.1016/j.actbio.2018.07.040.
    10.1016/j.actbio.2018.07.040
  12. Abreu, Catarina M.; Soares-dos-Reis, Ricardo; Melo, Pedro N.; Relvas, João B.; Guimarães, Joana; Sá, Maria José; Cruz, Andrea P.; Mendes Pinto, Inês. "Emerging Biosensing Technologies for Neuroinflammatory and Neurodegenerative Disease Diagnostics". Frontiers in Molecular Neuroscience 11 (2018): http://dx.doi.org/10.3389/fnmol.2018.00164.
    10.3389/fnmol.2018.00164
  13. Bouçanova, Filipa; Maia, André Filipe; Cruz, Andrea; Millar, Val; Mendes Pinto, Inês; Relvas, João Bettencourt; Domingues, Helena Sofia. "Collar occupancy: A new quantitative imaging tool for morphometric analysis of oligodendrocytes". Journal of Neuroscience Methods 294 (2018): 122-135. http://dx.doi.org/10.1016/j.jneumeth.2017.11.014.
    10.1016/j.jneumeth.2017.11.014
  14. Domingues, Helena S.; Cruz, Andrea; Chan, Jonah R.; Relvas, João B.; Rubinstein, Boris; Pinto, Inês Mendes. "Mechanical plasticity during oligodendrocyte differentiation and myelination". Glia 66 1 (2017): 5-14. http://dx.doi.org/10.1002/glia.23206.
    10.1002/glia.23206
  15. Sousa, Flávia; Cruz, Andrea; Fonte, Pedro; Pinto, Inês Mendes; Neves-Petersen, Maria Teresa; Sarmento, Bruno. "A new paradigm for antiangiogenic therapy through controlled release of bevacizumab from PLGA nanoparticles". Scientific Reports 7 1 (2017): http://dx.doi.org/10.1038/s41598-017-03959-4.
    10.1038/s41598-017-03959-4
  16. Braz, Sandra Oliveira; Cruz, Andrea; Lobo, Andrea; Bravo, Joana; Moreira-Ribeiro, Joana; Pereira-Castro, Isabel; Freitas, Jaime; et al. "Expression of Rac1 alternative 3' UTRs is a cell specific mechanism with a function in dendrite outgrowth in cortical neurons.". Biochimica et biophysica acta (2017): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:28274785&KeyUID=MEDLINE:28274785.
    10.1016/j.bbagrm.2017.03.002
  17. Cruz, Andrea; Torrado, Egídio; Carmona, Jenny; Fraga, Alexandra G.; Costa, Patrício; Rodrigues, Fernando; Appelberg, Rui; et al. "BCG vaccination-induced long-lasting control of Mycobacterium tuberculosis correlates with the accumulation of a novel population of CD4+IL-17+TNF+IL-2+ T cells". Vaccine 33 1 (2015): 85-91. http://dx.doi.org/10.1016/j.vaccine.2014.11.013.
    10.1016/j.vaccine.2014.11.013
  18. Cruz, Andrea; Ludovico, Paula; Torrado, Egidio; Gama, Jose Bernardo; Sousa, Jeremy; Gaifem, Joana; Appelberg, Rui; et al. "IL-17A promotes intracellular growth of Mycobacterium by inhibiting apoptosis of infected macrophages". Frontiers in Immunology 6 (2015): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000362114800001&KeyUID=WOS:000362114800001.
    10.3389/fimmu.2015.00498
  19. Curinha A; Oliveira Braz S; Pereira-Castro I; Cruz A; Moreira A. "Implications of polyadenylation in health and disease.". (2014): http://europepmc.org/abstract/med/25484187.
    10.4161/nucl.36360
  20. Carmona, J.; Cruz, A.; Moreira-Teixeira, L.; Sousa, C.; Sousa, J.; Osorio, N.S.; Saraiva, A.L.; et al. "Mycobacterium tuberculosis Strains Are Differentially Recognized by TLRs with an Impact on the Immune Response". PLoS ONE 8 6 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84879468975&partnerID=MN8TOARS.
    10.1371/journal.pone.0067277
  21. Fraga, A.G.; Cruz, A.; Martins, T.G.; Torrado, E.; Saraiva, M.; Pereira, D.R.; Meyers, W.M.; et al. "Mycobacterium ulcerans triggers T-cell immunity followed by local and regional but not systemic immunosuppression". Infection and Immunity 79 1 (2011): 421-430. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650893587&partnerID=MN8TOARS.
    10.1128/IAI.00820-10
  22. Teixeira-Coelho, M.; Cruz, A.; Carmona, J.; Sousa, C.; Ramos-Pereira, D.; Saraiva, A.L.; Veldhoen, M.; et al. "TLR2 deficiency by compromising p19 (IL-23) expression limits Th 17 cell responses to Mycobacterium tuberculosis". International Immunology 23 2 (2011): 89-96. http://www.scopus.com/inward/record.url?eid=2-s2.0-79551636533&partnerID=MN8TOARS.
    10.1093/intimm/dxq459
  23. Lima-Rodrigues, M.; Lamas, N.; Valle-Fernandes, A.; Cruz, A.; Vieira, A.; Oliveira, P.; Pedrosa, J.; et al. "The selective COX-2 inhibitor Etoricoxib reduces acute inflammatory markers in a model of neurogenic laryngitis but loses its efficacy with prolonged treatment". Inflammation Research 59 9 (2010): 743-753. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955652845&partnerID=MN8TOARS.
    10.1007/s00011-010-0185-5
  24. Cruz, A.; Fraga, A.G.; Fountain, J.J.; Rangel-Moreno, J.; Torrado, E.; Saraiva, M.; Pereira, D.R.; et al. "Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis". Journal of Experimental Medicine 207 8 (2010): 1609-1616. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955390095&partnerID=MN8TOARS.
    10.1084/jem.20100265
  25. Lima-Rodrigues, M.; Valle-Fernandes, A.; Lamas, N.; Cruz, A.; Baltazar, F.; Milanezi, F.; Nunes, R.; et al. "A new model of laryngitis: Neuropeptide, cyclooxygenase, and cytokine profile". Laryngoscope 118 1 (2008): 78-86. http://www.scopus.com/inward/record.url?eid=2-s2.0-37549072217&partnerID=MN8TOARS.
    10.1097/MLG.0b013e3181492400
  26. Gaspar, M.M.; Cruz, A.; Penha, A.F.; Reymão, J.; Sousa, A.C.; Eleutério, C.V.; Domingues, S.A.; et al. "Rifabutin encapsulated in liposomes exhibits increased therapeutic activity in a model of disseminated tuberculosis". International Journal of Antimicrobial Agents 31 1 (2008): 37-45. http://www.scopus.com/inward/record.url?eid=2-s2.0-37049038233&partnerID=MN8TOARS.
    10.1016/j.ijantimicag.2007.08.008
  27. Gaspar, M.M.; Cruz, A.; Fraga, A.G.; Castro, A.G.; Cruz, M.E.M.; Pedrosa, J.. "Developments on drug delivery systems for the treatment of mycobacterial infections". Current Topics in Medicinal Chemistry 8 7 (2008): 579-591. http://www.scopus.com/inward/record.url?eid=2-s2.0-44949217601&partnerID=MN8TOARS.
    10.2174/156802608783955629
  28. Cruz, A.; Khader, S.A.; Torrado, E.; Fraga, A.; Pearl, J.E.; Pedrosa, J.; Cooper, A.M.; Castro, A.G.. "Cutting edge: IFN-¿ regulates the induction and expansion of IL-17-producing CD4 T cells during mycobacterial infection". Journal of Immunology 177 3 (2006): 1416-1420. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746215298&partnerID=MN8TOARS.
  29. Marcos, N.T.; Pinho, S.; Grandela, C.; Cruz, A.; Samyn-Petit, B.; Harduin-Lepers, A.; Almeida, R.; et al. "Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated Sialyl-Tn antigen". Cancer Research 64 19 (2004): 7050-7057. http://www.scopus.com/inward/record.url?eid=2-s2.0-4944265751&partnerID=MN8TOARS.
    10.1158/0008-5472.CAN-04-1921
  30. Marcos NT; Cruz A; Silva F; Almeida R; David L; Mandel U; Clausen H; Von Mensdorff-Pouilly S; Reis CA. "Polypeptide GalNAc-transferases, ST6GalNAc-transferase I, and ST3Gal-transferase I expression in gastric carcinoma cell lines.". (2003): http://europepmc.org/abstract/med/12754287.
    10.1177/002215540305100607
Capítulo de livro
  1. Andrea Cruz; Catarina M. Abreu; Paulo P. Freitas; Inês Mendes Pinto. "Impedimetric Immunosensing for Neuroinflammatory Biomarker Profiling". 347-359. Springer {US, 2022.
    10.1007/978-1-0716-1712-0_14
  2. Cruz, Andrea; Abreu, Catarina ; Freitas, Paulo ; Mendes Pinto, Inês. Autor correspondente: Mendes Pinto, Inês. "Impedimetric Immunosensing for Neuroinflammatory Biomarker Profiling". In Neurodegenerative Diseases Biomarkers, 347-359. Springer Nature, 2021.
    Publicado
  3. Sousa, Flávia; Fonte, Pedro; Cruz, Andreia; Kennedy, Patrick J.; Pinto, Inês Mendes; Sarmento, Bruno. "Polyester-Based Nanoparticles for the Encapsulation of Monoclonal Antibodies". In Recombinant Glycoprotein Production, 239-253. Springer New York, 2017.
    Publicado • 10.1007/978-1-4939-7312-5_20
Poster em conferência
  1. Cruz, Andrea; Caldas, José; Abreu, Catarina; Freitas, Paulo; Oliveira, Arlindo; Mendes Pinto, Inês. "Mechanical traits uncover functional plasticity and identity of tissue-specific macrophages". Trabalho apresentado em American Society for Cell Biology and European Molecular Biology Organization Meeting (ASCB EMBO Meeting), USA, 2018.
  2. Flavia Sousa; Cruz, Andrea; Pedro Fonte, Inês Mendes Pinto, Maria Teresa Neves-Petersen, Bruno Sarmento. "An improvement of anti-angiogenic therapy achieved by bevacizumab delivery through PLGA nanocarriers". Trabalho apresentado em CRS Annual Meeting & Exposition New York, 2018.
  3. S Braz; Andrea P Cruz; Andrea Lobo; Joana Bravo; J Moreira-Ribeiro; Pereira, Joana; Isabel Pereira-Castro; et al. "Alternative 3' UTRs expression of Rac1 is a cell-type specific mechanism that controls neurite outgrowth". Trabalho apresentado em Regulation of RNA 3’end formation across eukaryotic genomes - EMBO Workshop, 2017.
  4. Cruz, Andrea; Raquel Queirós, Catarina Barata, Paulo P. Freitas, and Inês Mendes Pinto. "Electrochemical-based sensing device for the detection of inflammatory cytokines". Trabalho apresentado em 43rd International Conference on Micro and Nanoengineering, 18-22 Sep 2017, 2017.
  5. Cruz, Andrea; Helena Sofia Domingues, André Filipe Maia, João Bettencourt Relvas, Inês Mendes Pinto. "Identification of actomyosin-based biomarkers relevant for microglia activation". Trabalho apresentado em XIII European Meeting on Glial Cells in Health and Disease.8-11 July 2017, Edinburg, 2017.
  6. Flavia Sousa; Cruz, Andrea; Maria Teresa Neves-Petersen, Inês Mendes Pinto, Bruno Sarmento. "Study of stability and bioactivity of bevacizumab- loaded PLGA nanoparticles towards its controlled release". Trabalho apresentado em 43rd International Conference on Micro and Nanoengineering, 18-22 Sep 2017, Braga, 2017.
  7. Cruz, Andrea; Flavia Sousa; Pedro Fonte, Inês Mendes Pinto, Maria Teresa Neves-Petersen, Bruno Sarmento. "A new paradigm for antiangiogenic therapy through controlled release of bevacizumab". Trabalho apresentado em First SPLC-CRS Young Scientist Meeting, 23-24 April 2017, Santiago de Compostela, Spain, 2017.
  8. Andrea P Cruz; Helena Sofia Domingues; Braz, Sandra O.; Filipa Bouçanova; Alexandra Moreira; João B. Relvas. "The role of PABPC1 and YBX1 in Oligodendrocyte differentiation". Trabalho apresentado em XIV Meeting of the Portuguese Society for Neuroscience, 2015.
  9. Helena Sofia Domingues; Cruz, Andrea; Filipa Boucanova, Maria Azevedo, Ana Seixas, Sandra Braz, João Relvas. "The oligodendrocyte “processosome”: identification of new regulators of differentiation and myelination". Trabalho apresentado em The XII European Meeting on Glial Cell Function in Health and Disease, Bilbao, Spain, July 15 - 18, 2015, 2015.
  10. Cruz, Andrea; Sofia Domingues, Sandra Braz, Alexandra Moreira, João B Relvas. "Role of PABPC1 and YBX1 in oligodendrocyte differentiation". Trabalho apresentado em XIV Meeting of the Portuguese Society for neurosciences, 2015.
  11. Braz, Sandra O.; João B. Relvas; Alexandra Moreira; Andrea P Cruz. "Alternative polyadenylation of Rho GTPases in central nervous system cells". Trabalho apresentado em I3S 4th Annual Meeting, 2014.
  12. Andrea P Cruz; Helena Sofia Domingues; Braz, Sandra O.; Alexandra Moreira; João B. Relvas. "Role of RNA-binding proteins in oligodendrocyte differentiation". Trabalho apresentado em I3S 4th Annual Meeting, 2014.
  13. Braz, Sandra O.; João B. Relvas; Alexandra Moreira; Andrea P Cruz. "Alternative Polyadenylation of Rho GTPases: a gene/cell specific process". Trabalho apresentado em The complex life of mRNA, EMBL, 2014.
  14. Cruz, Andrea; Sofia Domingues, Sandra Braz, Alexandra Moreira, João B Relvas. "Role of PABPC1 and YBX1 in oligodendrocyte differentiation". Trabalho apresentado em The EMBO | EMBL Symposium “Complex Life of mRNA”, Heidelberg, Germany, 5-8 October 2014, 2014.
  15. Sandra O. Braz, João Relvas, Alexandra Moreira; Cruz, Andrea. "Alternative polyadenylation of Rho GTPases: a gene and cell specific process". Trabalho apresentado em The EMBO | EMBL Symposium “Complex Life of mRNA”, Heidelberg, Germany, 5-8 October 2014, 2014.
  16. Cruz, Andrea; Sandra Braz; João Relvas and Alexandra Moreira. "Expression Regulation of Rho GTPases family members during oligodendrocytes differentiation and myelination". Trabalho apresentado em 7º Encontro Investigação Jovem da Universidade do Porto, Porto, Portugal, 12 -14 February 2014, 2014.
  17. Ana Cláudia Leite; Cruz, Andrea; Vítor Espírito Santo, Lúcia Moreira-Teixeira, Manuela Gomes, Rui L. Reis, Maria Alice Carvalho and Jorge Pedrosa. "Development of purine derivatives with activity against Mycobacterium tuberculosis Infections: potential of chitosan-coated magnetic nanoparticles for controlled delivery". Trabalho apresentado em III ICVS/3B's - Associate Laboratory Meeting - June 28th 2013, Braga, 2013.
  18. Jenny Carmona; Cruz, Andrea; Carole Sousa, Nuno S. Osório, Ana L. Saraiva, Stefan Svenson, Gunilla Kallenius, Jorge Pedrosa, Fernando Rodrigues; António G. Castro and Margarida Saraiva. "Mycobacterium tuberculosis strains are differentially recognized by TLRs with an impact on innate immune responses and the outcome of infection". Trabalho apresentado em European Congress of Immunology, Glasgow, 5-8 Set 2012, 2012.
    10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3166
  19. Jenny Carmona; Cruz, Andrea; Carole Sousa, Nuno S. Osório, Ana L. Saraiva, Stefan Svenson, Gunilla Kallenius, Jorge Pedrosa, Fernando Rodrigues; António G. Castro and Margarida Saraiva. "Differential recognition of Mycobacterium tuberculosis strains by TLRs impacts innate immune responses and the outcome of infection". Trabalho apresentado em Jenny Carmona, Andrea Cruz, Carole Sousa, Nuno S. Osório, Ana L. Saraiva, Stefan Svenson, Gunilla Kallenius, Jorge Pedrosa, Fernando Rodrigues, António G. Castro and Margarida Saraiva., 2012.
  20. Cruz, Andrea; Carole Sousa, Fernando Rodrigues, Paula Ludovico, Andrea Cooper, Jorge Pedrosa, António G. Castro and Margarida Saraiva. "IL-17 and IL-10 cooperate to prevent apoptosis of Mycobacterium-infected macrophages". Trabalho apresentado em 6th National Meeting on Cell Signaling, Braga, Portugal, 2012, 2012.
  21. Cruz, Andrea; Jenny Carmona, Alexandra G. Fraga, Carole Sousa, Daniela Pereira, Patrício Costa; Fernando Rodrigues, Rui Appelberg, Margarida Correia-Neves, Andrea M. Cooper, Margarida Saraiva; Jorge Pedrosa, and António G. Castro. "BCG vaccination inducing long-term protection against Mycobacterium tuberculosis correlates with the differentiation of IL-17/IL-2/TNF producing T cells". Trabalho apresentado em SPI simpósio -Tuberculosis From the hospital to the bench and back, Life and Health Sciences Research Institute, School of Health Science, Minho University, Braga, Portugal, 2012, 2012.
  22. Cruz, Andrea; Maria Teixeira-Coelho, Pedro Ferreirinha. "Mycobacterium tuberculosis and M. bovis BCG differentially trigger IL-10 production by dendritic cells with an impact on IL-12". Trabalho apresentado em SPI simpósio -Tuberculosis From the hospital to the bench and back, Life and Health Sciences Research Institute, School of Health Science, Minho University, Braga, Portugal, 2012, 2012.
  23. Jenny Carmona; Cruz, Andrea; Carole Sousa, Ana L. Saraiva, Gunilla Källenius, Stefan Svenson, Jorge Pedrosa, Fernando Rodrigues, António G. Castro; Margarida Saraiva. "Differential TLR usage by Mycobacterium tuberculosis strains modulates innate immune responses with an impact on the outcome of infection". Trabalho apresentado em Poster presented in the SPI simpósio -Tuberculosis From the hospital to the bench and back, Life and Health Sciences Research Institute, School of Health Science, Minho University, Braga, Portugal, 2012., 2012.
  24. Maria Teixeira-Coelho, Pedro Ferreirinha; Cruz, Andrea; Carole Sousa, Joana Alves, Jorge Pedrosa, Margarida Saraiva, António Gil Castro. "Mycobacterium tuberculosis or M. bovis BCG regulate IL-12 expression differently in infected Dendritic Cells". Trabalho apresentado em 8th International Conference on the Pathogenesis of Mycobacterial Infection, Stockholm, June 30 - July 3 2011, 2011.
  25. Cruz, Andrea; Carole Sousa, Maria Teixeira-Coelho, Joana Alves, Jorge Pedrosa, A. Gil Castro and Margarida Saraiva. "IL-17 interferes with p53 and prevents apoptosis of Mycobacterium-infected macrophages". Trabalho apresentado em Poster presented in the XXXVI Reunião anual da Sociedade Portuguesa de Imunologia, Braga, 2010., 2010.
  26. Cruz, Andrea; Alexandra G. Fraga, Daniela Pereira, Ana L. Saraiva, Margarida Saraiva, Margarida Correia- Neves, Andrea M Cooper; Jorge Pedrosa, and António G. Castro. "Control of Mycobacterium tuberculosis infection depends on the time of previous exposure to BCG vaccination". Trabalho apresentado em Poster presented in the MicroBiotec09, Vilamoura, 2009, 2009.
  27. Margarida Saraiva; Cruz, Andrea; Maria Teixeira-Coelho, Jenny Carmona, Carole Sousa, Daniela Ramos-Pereira, Jorge Pedrosa and António G. Castro. "TLR2 controls IL-17 responses to Mycobacterium tuberculosis". Trabalho apresentado em Poster presented in the MicroBiotec09, Vilamoura, 2009, 2009.
  28. Margarida Saraiva; Cruz, Andrea; Carole Sousa, Jenny Carmona, Jorge Pedrosa and António G. Castro. "Mycobacterium tuberculosis and M. bovis BCG induce a differential expression of IL-12 family of cytokines on BMDC". Trabalho apresentado em Margarida Saraiva, Andrea Cruz, Carole Sousa, Jenny Carmona, Jorge Pedrosa and António G. Castro, 2009.
  29. Daniela Ramos-Pereira, Maria Teixeira-Coelho; Cruz, Andrea; Alexandra Fraga, Carole Sousa, Jenny Carmona, Margarida Saraiva, Paulo Vieira, Jorge Pedrosa and António G. Castro. "Over-expression of IL-10 increases resistance to Mycobacterium tuberculosis infection". Trabalho apresentado em Poster presented XXXV Reunião anual da Sociedade Portuguesa de Imunologia, Lisboa, 2009., 2009.
  30. Carole Sousa, Maria Teixeira-Coelho; Cruz, Andrea; Jenny Carmona, Jorge Pedrosa, A. Gil Castro and Margarida Saraiva. "Dendritic cells exposed to Mycobacterium tuberculosis and Mycobacterium. bovis BCG induce a distinct balance of T helper responses". Trabalho apresentado em Poster presented in the XXXV Reunião anual da Sociedade Portuguesa de Imunologia, Lisboa, 2009, 2009.
  31. Cruz, Andrea; Alexandra G. Fraga, Daniela Pereira, Ana L. Saraiva, Margarida Saraiva, Margarida Correia- Neves; Andrea M Cooper, Jorge Pedrosa and António G. Castro. "Dynamics of Th1 and Th17 cells varies with time post-BCG vaccination: implications on protection conferred to Mycobacterium tuberculosis infection". Trabalho apresentado em Poster presented in the XXXIV Reunião da Sociedade Portuguesa de Imunologia, Porto, 2008., 2008.
  32. Cruz, Andrea; Egídio Torrado, António Barroso, Jenny Carmona, Andrea Cooper, Jorge Pedrosa and António G. Castro. "IL-17 inhibits IFN-g inducing bactericidal activity on macrophages infected with mycobacteria". Trabalho apresentado em Poster presented in the 1st Mediterranean Workshop Clinical Immunology, Évora, 2006., 2006.
  33. Manuel Lima-Rodrigues, Nuno Lamas, Artur Vieira, Ana Valle Fernandes; Cruz, Andrea; Fernanda Milanezi, António G. Castro, Jorge Pedrosa, Fátima Baltazar, Rui M. Reis,Armando Almeida. "Changes in the expression of inflammatory mediators following neurogenic laryngitis: therapeutical trial with etoricoxib". Trabalho apresentado em Poster presented in the XLI Congresso da Sociedade Portuguesa de Microscopia, Braga, 2006., 2006.
  34. Cruz, Andrea; António Barroso, Jenny Carmona, Andrea Cooper, Jorge Pedrosa and A. G. Castro. "IL-17 inhibits the bactericidal activity of macrophages infected with Mycobacterium by preventing cell death". Trabalho apresentado em Poster presented in the XXXII Reunião da Sociedade Portuguesa de Imunologia, Braga, 2006., 2006.
  35. Cruz, Andrea; Alexandra Fraga, Egídio Torrado, Andrea Cooper, Jorge Pedrosa and A. G. Castro. "Th17 cells inducing a massive recruitment of neutrophils may play a role in Koch´s reaction". Trabalho apresentado em XXXII Reunião da Sociedade Portuguesa de Imunologia, Braga, 2006., 2006.
  36. Manuel Lima-Rodrigues, Ana ValleFernandes, Nuno Lamas, Artur Vieira; Cruz, Andrea; Jorge Pedrosa, António G Castro, Fátima Baltazar, Rui M Reis, Rui Nunes, Armando Almeida. "Possible alternative therapies to chronic laryngitis and laryngeal cancer: the use of COX-2 specific inhibitors and detection of tumoral markers". Trabalho apresentado em Poster presented in the XXXII Reunião da Sociedade Portuguesa de Imunologia, Braga, 2006., 2006.
  37. Alexandra G. Fraga, Egidio Torrado, Daniela Pereira, Jenny Carmona; Cruz, Andrea; António G. Castro, and Jorge Pedrosa. "IFNg induces LRG-47 and Nitric Oxide in macrophages, playing a protective role in infection by a mycolactone-negative strain of Mycobacterium ulcerans". Trabalho apresentado em ”. Poster presented in the XXXII Reunião da Sociedade Portuguesa de Imunologia, Braga, 2006., 2006.
  38. Cruz, Andrea; Shabaana A. Khader , Egidio Torrado, Alexandra Fraga, John E. Pearl, Jorge Pedrosa, Andrea M. Cooper, António G. Castro. "IL-17-producing CD4 T cells induced during mycobacterial infection are regulated by IFNg”". Trabalho apresentado em ”. Poster presented in the II Simpósio Nacional de Citocinas, Coimbra, 2006, 2006.
  39. Cruz, Andrea; Shabaana A. Khader , Egidio Torrado, Alexandra Fraga, John E. Pearl, Jorge Pedrosa; Andrea M. Cooper, António G. Castro. "IFNg regulates the induction and expansion of IL-17-producing CD4 T cells during mycobacterial infection". Trabalho apresentado em Poster presented in the Keystone Symposium Determinants of Host Resistance from Experimental Models to Human Disease, Colorado-USA, 2006, 2006.
  40. Cruz, Andrea; John E. Pearl, Shabaana A. Khader, Alejandra Solache, Jorge Pedrosa, António G. Castro and Andrea M. Cooper. "BCG Infection Induces IL-17 Producing Antigen-specific T cells". Trabalho apresentado em Poster presented in the 12th International Congress of Immunology and 4th Annual Conference of FOCIS, Montreal- Canada, 2004, 2004.
  41. Nuno Marcos, Catarina Grandela; Cruz, Andrea; Anne Harduin-Lepers, Leonor David, Filipe Silva, Raquel Almeida, Jan Kihlberg, Celso A. Reis. "Expression and characterisation of recombinant human ST6GalNAc-I and ST6GalNAc-II". Trabalho apresentado em Poster presented in the Mucins in Health and Disease 7th International Workshop on Carcinoma associated Mucins, Crete - Grécia, 2003, 2003.
  42. Maria Gonzalez-Pajuelo, José Andrade; Cruz, Andrea; Carlos Monagas, Isabel Vasconcelos. "1,3 – Propanediol continuous production by Clostridium butyricum VPI1718: Effect of dilution rate and substrate concentration". Trabalho apresentado em Poster presented in the IXth International Congress of Bacteriology & Applied Microbiology, Sydney-Austrália, 16-20 Agosto, 1999., 1999.
Resumo em conferência
  1. Carmona, Jenny; Cruz, Andrea; Sousa, Carole; Osório, Nuno S.; Saraiva, Ana L.; Svenson, Stefan; Kallenius, Gunilla; et al. "Mycobacterium tuberculosis strains are differentially recognized by TLRs with an impact on innate immune responses and the outcome of infection: P1313". Trabalho apresentado em Immunology Journal, 2012.
    Publicado
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2017/05/24 Identification of actomyosin-based biomarkers relevant for microglia activation II symposium Portuguese Glial Network
(Portugal)
2017 Study of stability and bioactivity of bevacizumab- loaded PLGA nanoparticles towards its controlled release 43rd International Conference on Micro and Nanoengineering
(Portugal)
2017 A new paradigm for antiangiogenic therapy through controlled release of bevacizumab First SPLC-CRS Young Scientist Meeting
(Espanha)
2012 BCG vaccination induced IL-17+TNF+IL-2+ polyfunctional memory T cells correlated with increased protection against M. tuberculosis XXXVIII Reunião Anual da Sociedade Portuguesa de Imunologia
SPI (Portugal)
2009 Development of an adaptive immune response in the draining lymph node during Mycobacterium ulcerans infection 30th Annual Congress of European Society for Mycobacteriology,
2009 IL-17 responses to Mycobacterium tuberculosis are compromised in the absence of TLR-2 XXXV Reunião Anual da Sociedade Portuguesa de Imunologia
2008 IL-17 inhibits the bactericidal activity of macrophages infected with Mycobacterium by preventing apoptosis, through an IL-10 dependent mechanism course Immunoregulation in Infectious Diseases: From Immunity to Bugs and Back
2008 Koch like reaction associates with an increased number of IL-17 producing T cells 7th International Conference of Pathogenesis of Mycobacterial Infections7th International Conference of Pathogenesis of Mycobacterial Infections
2006 IL-17-producing CD4 T cells induced during mycobacterial infection are regulated by IFNg II Simpósio Nacional de Citocinas
2004 IFNg regulates the production of IL-17 by antigen-specific T cells following infection by M. bovis BCG XXX Reunião Anual da Sociedade Portuguesa de Imunologia

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2014 - 2014 Role of RNA-Binding Proteins in Microglia Activation/Deactivation
Orientador de Ana Keating
Mestrado em Investigação Biomédica (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2014 - 2014 Expression Regulation of Rho GTPases family members during olygodendrocytes differentiation and myelination
Orientador de Sandra Braz
Universidade de Aveiro, Portugal
2012 - 2012 Regulation of macrophages apoptosis: role of IL-17 e IL-10
Orientador
 Mestrado Integrado em Medicina (Mestrado)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2011 - 2011 Orientation of the experimental phase of the “Projectos de Opção III” – of the Medicine Master's student Sara Monteiro – “The role of IL-17 and IL-10 in the regulation of apoptosis of infected macrophages by mycobacterias”
Orientador
 Mestrado Integrado Medicina (Outra)
Universidade do Minho Escola de Medicina, Portugal
2009 - 2009 Regulation of macrophages apoptosis infected with mycobacterias: role of IL-17
Orientador de Rafael Velho
 Mestrado Integrado em Medicina (Mestrado)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2009 - 2009 Orientation of the experimental phase of the “Projectos de Opção I” – of the Medicine Master's student Nuno Oliveira – “Effect of IL-17 in the gene expression of macrophages of infected with Mycobacterium bovis BCG”, conducted at Life and Health Sciences Research Institute, School Medicine
Orientador
Universidade do Minho Escola de Medicina, Portugal
2008 - 2008 Orientation of the laboratorial rotation of the student Teresa Pinto integrated in the MD-PhD program of the Life and Health Sciences Research Institute, School of Health Science, Minho University
Orientador
Universidade do Minho Escola de Medicina, Portugal
2008 - 2008 Orientation of the experimental phase of the “Projectos de Opção V” – of the Medicine Master's student Rafael Velho – “Role of IL-17 in the bactericide activity of macrophages of infected with mycobacterias” conducted at Life and Health Sciences Research Institute, School of Health Science, Minho University
Orientador de Rafael Velho
Universidade do Minho Escola de Medicina, Portugal
2007 - 2007 Co-Orientation of the experimental phase of the “Projectos de Opção IV” – of the Medicine Master's student Eduardo Ferreira - “The Role of IL-17 in Tuberculosis” conducted at Life and Health Sciences Research Institute, School of Medicine, Minho University
Coorientador
Universidade do Minho Escola de Medicina, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2006 - 2013 Co-organization at the Life and Health Sciences Research Institute, School of Medicine, Minho University of "Semana da Epidemia de Ciência" (2006 - 2013)
Simpósio (Coorganizador)
 Universidade do Minho Escola de Medicina, Portugal
2006 - 2013 Semana da Ciência e da Tecnologia promovida pela Agência Nacional para a Cultura Científica e Tecnológica, Ciência Viva; being scientific coordinator of the activities "Acids and Bases" and "Harmful Effects of UV Radiation (2006 - 2013)
Encontro (Coorganizador)
 Universidade do Minho Escola de Medicina, Portugal
2006/10 - 2006/10 Co-organization at Life and Health Sciences Research Institute, School of Medicine, Minho University together with Jorge Pedrosa and António Gil Castro (ECS) e Manuel Vilanova (ICBAS), of the XXXII Reunião da Sociedade Portuguesa de Imunologia (SPI): “Innate and Acquired Immunity: evolution and regulation (2006)
Conferência (Coorganizador)

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2009 - Atual Fundamentos de Biopatologia, Farmacologia e Terapêutica Licenciatura em Enfermagem (Licenciatura) Universidade do Minho, Portugal
2009 - Atual Graduate courses: “Host Pathogen Interaction” and “Fundamentals in Immunology and Infection.” PhD program in Health Sciences, School of Medicine, Minho University Biomedical Engendering Master, from School of Engendering, Minho University Bioengineering Master, from School of Engendering, Minho University School of Medicine (Doutoramento) Universidade do Minho, Portugal
2009 - 2010 Unidade Curricular Biologia Celular e Molecular Licenciatura em Enfermagem (Licenciatura) Universidade do Minho, Portugal
2004 - 2010 "Biopatologia e Introdução Terapeutica" (Mestrado) Universidade do Minho Escola de Medicina, Portugal

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2004 - 2013 Responsible together with Jorge Pedrosa and Alexandra Fraga, of the security and maintenance of the Laboratory Safety Level 3 (BSL3) of Life and Health Sciences Research Institute, School of Health Sciences, Minho University
Outro

Tutoria

Tópico Nome do aluno
2019 - Atual Biosensors, Nanotechnology and Molecular Medicine Maria Vieira
2016 - Atual Computational Modelling Diogo Fernandes
2016 - 2019 Biosensors, Nanotechnology and Molecular Medicine Catarina Abreu
2016 - 2018 Biosensors, Nanotechnology and Molecular Medicine Flávia Sousa
2016 - 2017 Biosensors, Nanotechnology and Molecular Medicine Ana Catarina de Almeida Barata
Distinções

Prémio

2012 Award for the Best Poster in the SPI symposium
Sociedade Portuguesa de Imunologia, Portugal
2010 Excellence Award in Immunology Pulido Valente Ciência 2010 - Execellence in Science
Fundação para a Ciência e a Tecnologia, Portugal

Fundação Pulido Valende, Portugal
2010 Award for Best SPI Paper Award 2010
Sociedade Portuguesa de Imunologia, Portugal
2009 Award for the Best Poster in congress MicroBiotec09
Sociedade Portuguesa de Microbiologia, Portugal

Sociedade Portuguesa de Biotecnologia, Portugal
2006 Excellence Award in Immunology Mário Arala Chaves 2006
Sociedade Portuguesa de Imunologia, Portugal
2006 Award for the Best Poster in II Simpósio Nacional de Citocinas 2006
Universidade de Coimbra, Portugal
2006 Scholarships Award to attend the Keystone Symposium
Keystone Symposia, Estados Unidos

Outra distinção

2016 Marie Curie Fellow
European Union, Bélgica